MCID: ADL045
MIFTS: 15

Adult Ependymoblastoma

Categories: Cancer diseases, Fetal diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Adult Ependymoblastoma

MalaCards integrated aliases for Adult Ependymoblastoma:

Name: Adult Ependymoblastoma 12 71

Classifications:



External Ids:

Disease Ontology 12 DOID:7631
NCIt 49 C8290
UMLS 71 C0281330

Summaries for Adult Ependymoblastoma

MalaCards based summary : Adult Ependymoblastoma and has symptoms including vomiting and headache. The drugs Donepezil and Fentanyl have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and t cells.

Related Diseases for Adult Ependymoblastoma

Diseases in the Ependymoblastoma family:

Adult Ependymoblastoma

Symptoms & Phenotypes for Adult Ependymoblastoma

UMLS symptoms related to Adult Ependymoblastoma:


vomiting, headache

Drugs & Therapeutics for Adult Ependymoblastoma

Drugs for Adult Ependymoblastoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 116)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Donepezil Approved Phase 3 120014-06-4 3152
2
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
3
Dopamine Approved Phase 3 51-61-6, 62-31-7 681
4
Methylphenidate Approved, Investigational Phase 3 113-45-1 4158
5 Pancreatic Polypeptide Investigational Phase 3 59763-91-6
6 Central Nervous System Depressants Phase 3
7 Analgesics Phase 3
8 Nootropic Agents Phase 3
9 Cholinergic Agents Phase 3
10 Cholinesterase Inhibitors Phase 3
11 Liver Extracts Phase 3
12 Cola Phase 3
13 Narcotics Phase 3
14 Anesthetics Phase 3
15 Analgesics, Opioid Phase 3
16 Anesthetics, General Phase 3
17 Adjuvants, Anesthesia Phase 3
18 Anesthetics, Intravenous Phase 3
19 Central Nervous System Stimulants Phase 3
20 Dexmethylphenidate Hydrochloride Phase 3
21 Dopamine Uptake Inhibitors Phase 3
22 Neurotransmitter Agents Phase 3
23 Dopamine Agents Phase 3
24
Pregabalin Approved, Investigational Phase 2 148553-50-8 5486971
25
Levetiracetam Approved Phase 2 102767-28-2 441341
26
Methotrexate Approved Phase 2 59-05-2, 1959-05-2 126941
27
Cisplatin Approved Phase 2 15663-27-1 84093 441203 2767
28
leucovorin Approved Phase 2 58-05-9 6006 143
29
Cyclophosphamide Approved, Investigational Phase 2 6055-19-2, 50-18-0 2907
30
Etoposide Approved Phase 2 33419-42-0 36462
31
Vincristine Approved, Investigational Phase 2 57-22-7, 2068-78-2 5978
32
Aldesleukin Approved Phase 2 85898-30-2, 110942-02-4
33
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
34
Iodine Approved, Investigational Phase 2 7553-56-2 807
35
Acetaminophen Approved Phase 2 103-90-2 1983
36
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 2 1177-87-3
37
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
38
Diphenhydramine Approved, Investigational Phase 2 58-73-1, 147-24-0 3100
39
Promethazine Approved, Investigational Phase 2 60-87-7 4927
40
Calcium Approved, Nutraceutical Phase 2 7440-70-2 271
41
Folic acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
42 Antineoplastic Agents, Immunological Phase 1, Phase 2
43 Hormones Phase 2
44 Anticonvulsants Phase 2
45 Anti-Anxiety Agents Phase 2
46 Tranquilizing Agents Phase 2
47 Psychotropic Drugs Phase 2
48 Calcium, Dietary Phase 2
49 calcium channel blockers Phase 2
50 Anti-Retroviral Agents Phase 1, Phase 2

Interventional clinical trials:

(show all 33)
# Name Status NCT ID Phase Drugs
1 Phase III Double Blind, Placebo Controlled Study of Donepezil in the Irradiated Brain Completed NCT00369785 Phase 3 donepezil hydrochloride;Placebo
2 A Randomized, Double-blind, Placebo-controlled Multi-center Study to Evaluate the Safety and Efficacy of Fentanyl Sublingual Spray (Fentanyl SL Spray) for the Treatment of Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
3 A Phase III, Double-Blind, Prospective Randomized Clinical Trial of the Effect of D-threo-methylphenidate HCl (d-MPH) on Quality of Life in Brain Tumor Patients Receiving Radiation Therapy Terminated NCT00031798 Phase 3 methylphenidate hydrochloride
4 PHASE I STUDY OF ANTI-TENASCIN MONOCLONAL ANTIBODY 131I 81C6 VIA SURGICALLY CREATED CYSTIC RESECTION CAVITY IN THE TREATMENT OF PATIENTS WITH PRIMARY OR METASTATIC MALIGNANT BRAIN TUMORS Completed NCT00002752 Phase 1, Phase 2
5 Levetiracetam and Pregabalin for Monotherapy in Patients With Brain Tumors and Seizures. A Phase II Randomized Study. Completed NCT00629889 Phase 2 levetiracetam;pregabalin
6 A Phase I/II Study of Local Field Irradiation and Temozolomide Followed by Continuous Infusion Plerixafor as an Upfront Therapy for Newly Diagnosed Glioblastoma GBM Completed NCT01977677 Phase 1, Phase 2 temozolomide;plerixafor
7 Phase I Study of Intra-Tumoral, Radiolabeled, Anti-Tenascin Monoclonal Antibody 81C6 in the Treatment of Patients With Malignant Primary Brain Tumors Completed NCT00003478 Phase 1, Phase 2
8 Dose Intensive Chemotherapy for Patients Greater Than or Equal To 10 Years of Age With Newly Diagnosed High Stage Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumors (PNET) and Ependymoma: A Feasibility Study of an Intensive Induction Chemotherapy Regimen Followed by Standard Irradiation Completed NCT00006258 Phase 2 cisplatin;cyclophosphamide;etoposide;methotrexate;vincristine sulfate
9 Donepezil and EGb761 in Improving Neurocognitive Function in Patients Who Have Previously Undergone Radiation Therapy for Primary Brain Tumor or Brain Metastases Completed NCT00070161 Phase 2 donepezil hydrochloride
10 Phase II Trial Of High Dose Cyclophosphamide, Cisplatin And Carmustine With Stem Cell Reconstitution Followed By Specific Cellular Therapy In Patients With Recurrent Or Refractory Brain Tumors Completed NCT00014573 Phase 2 carmustine;cisplatin;cyclophosphamide;paclitaxel
11 Phase II Study of Intrathecal I-3F8 in Patients With GD2-Expressing Central Nervous System and Leptomeningeal Neoplasms Active, not recruiting NCT00445965 Phase 2
12 Defining Functional Tissue in Brain Tumors With Integrated Neuroimaging (Pilot Study) Withdrawn NCT00005083 Phase 2
13 Photodynamic Therapy For Childhood Brain Tumors, A Phase I Study Unknown status NCT00002647 Phase 1 verteporfin
14 PROTOCOL FOR A PHASE I STUDY OF INTRACYSTIC ANTI-TENASCIN MONOCLONAL ANTIBODY 131I 81C6 IN THE TREATMENT OF PATIENTS WITH RECURRENT CYSTIC GLIOMAS Completed NCT00002753 Phase 1
15 PHASE I, OPEN LABEL, MULTICENTER DOSE ESCALATION STUDY OF GLIADEL IN PATIENTS WITH RECURRENT MALIGNANT GLIOMA Completed NCT00004028 Phase 1 carmustine
16 A Phase I Trial Of A Thalidomide Analog, CC-5013, For The Treatment Of Patients With Recurrent High-Grade Gliomas Completed NCT00036894 Phase 1 lenalidomide
17 Phase I Study of Intrathecal 131-I-3F8 Monoclonal Antibody in Patients With GD2 Positive Leptomeningeal Neoplasms Completed NCT00003022 Phase 1
18 Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2 Completed NCT01082926 Phase 1
19 A Pilot Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors Completed NCT00784914 Phase 1 temsirolimus
20 A Phase I Trial of Subcutaneous And/Or Oral Calcitriol [(1,25-COH)2D3] and Carboplatin in Advanced Solid Tumors Completed NCT00008086 Phase 1 carboplatin
21 A Phase I Study of Bortezomib and Temozolomide in Patients With Refractory Solid Tumors Completed NCT00544284 Phase 1 bortezomib;temozolomide
22 A PHASE I STUDY OF THE COMBINATION OF CAI AND PACLITAXEL IN ADULT PATIENTS WITH REFRACTORY CANCERS OR LYMPHOMA Completed NCT00019019 Phase 1 carboxyamidotriazole;paclitaxel
23 A Phase I, Open-Label, Maximum Tolerated Single-Cycle and Four-Cycle Dose-Finding Study to Evaluation the Safety and Tolerability of 90Y-SMT 487 Administered by Intravenous Infusion to Subjects With Refractory Somatostatin-Receptor Positive Tumors Completed NCT00006368 Phase 1
24 Phase I Pharmacokinetic Trial of Thalidomide and Docetaxel: A Regimen Based on Anti-Angiogenic Therapeutic Principles Completed NCT00049296 Phase 1 docetaxel;thalidomide
25 A Phase I Study of an Oral Histone Deacetylase Inhibitor, MS-275, in Refractory Solid Tumors and Lymphomas Completed NCT00020579 Phase 1 entinostat
26 Mutant MGMT Gene Transfer Into Human Hematopoietic Progenitors to Protect Hematopoiesis During O6-Benzylguanine (BG, NSC 637037) and Carmustine Followed by Temozolomide Therapy of Advanced Solid Tumors Terminated NCT00003567 Phase 1 O6-benzylguanine;carmustine;temozolomide
27 Identification of Genes Involved in the Pathogenesis of Gliomas by Transcriptome Analysis Completed NCT00967200
28 Temozolomide Induced Changes in Semen/Sperm Analysis in Men With Newly Diagnosed, Progressive or Recurrent Primary Malignant Brain Tumors Completed NCT00499798
29 Magnetic Resonance Correlates of Glioma Tumor Burden Completed NCT00005082
30 Prospective Study on the Short-Term Adverse Effects From Gamma Knife Radiosurgery Completed NCT00255671
31 San Francisco Bay Area Adult Glioma Prognosis Study Protocol Completed NCT01009307
32 A Pharmacokinetic Participation Questionnaire Study Completed NCT00890435
33 Perfusion Magnetic Resonance Imaging of Brain Tumors: Correlation With Indicators of Angiogenesis Withdrawn NCT00005790

Search NIH Clinical Center for Adult Ependymoblastoma

Genetic Tests for Adult Ependymoblastoma

Anatomical Context for Adult Ependymoblastoma

MalaCards organs/tissues related to Adult Ependymoblastoma:

40
Brain, Liver, T Cells

Publications for Adult Ependymoblastoma

Variations for Adult Ependymoblastoma

Expression for Adult Ependymoblastoma

Search GEO for disease gene expression data for Adult Ependymoblastoma.

Pathways for Adult Ependymoblastoma

GO Terms for Adult Ependymoblastoma

Sources for Adult Ependymoblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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