MCID: ADL045
MIFTS: 16

Adult Ependymoblastoma

Categories: Cancer diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Adult Ependymoblastoma

MalaCards integrated aliases for Adult Ependymoblastoma:

Name: Adult Ependymoblastoma 12 74

Classifications:



External Ids:

Disease Ontology 12 DOID:7631
NCIt 51 C8290
UMLS 74 C0281330

Summaries for Adult Ependymoblastoma

MalaCards based summary : Adult Ependymoblastoma and has symptoms including vomiting and headache. The drugs Fentanyl and Donepezil have been mentioned in the context of this disorder. Affiliated tissues include brain, bone and liver.

Related Diseases for Adult Ependymoblastoma

Diseases in the Ependymoblastoma family:

Adult Ependymoblastoma

Symptoms & Phenotypes for Adult Ependymoblastoma

UMLS symptoms related to Adult Ependymoblastoma:


vomiting, headache

Drugs & Therapeutics for Adult Ependymoblastoma

Drugs for Adult Ependymoblastoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 134)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
2
Donepezil Approved Phase 3,Phase 2 120014-06-4 3152
3
Methylphenidate Approved, Investigational Phase 3 113-45-1 4158
4
Dopamine Approved Phase 3 62-31-7, 51-61-6 681
5 Pancreatic Polypeptide Investigational Phase 3,Phase 1 59763-91-6
6 Narcotics Phase 3
7 Adjuvants, Anesthesia Phase 3
8 Analgesics Phase 3,Phase 2,Phase 1
9 Anesthetics, Intravenous Phase 3
10 Liver Extracts Phase 3,Phase 1
11 Anesthetics, General Phase 3
12 Anesthetics Phase 3
13 Analgesics, Opioid Phase 3
14 Central Nervous System Depressants Phase 3,Phase 2
15 Peripheral Nervous System Agents Phase 3,Phase 2,Phase 1
16 Cola Phase 3,Phase 1
17 Cholinesterase Inhibitors Phase 3,Phase 2
18 Neurotransmitter Agents Phase 3,Phase 2
19 Nootropic Agents Phase 3,Phase 2
20 Cholinergic Agents Phase 3,Phase 2
21 Dexmethylphenidate Hydrochloride Phase 3
22 Dopamine Agents Phase 3
23 Central Nervous System Stimulants Phase 3
24 Dopamine Uptake Inhibitors Phase 3
25 Neurotransmitter Uptake Inhibitors Phase 3
26
Temozolomide Approved, Investigational Phase 1, Phase 2 85622-93-1 5394
27
Pregabalin Approved, Illicit, Investigational Phase 2 148553-50-8 5486971
28
Levetiracetam Approved, Investigational Phase 2 102767-28-2 441341
29
Aldesleukin Approved Phase 2,Phase 1 110942-02-4, 85898-30-2
30
Paclitaxel Approved, Vet_approved Phase 2,Phase 1 33069-62-4 36314
31
Carmustine Approved, Investigational Phase 2,Phase 1 154-93-8 2578
32
Lenograstim Approved, Investigational Phase 2,Phase 1 135968-09-1
33
Cyclophosphamide Approved, Investigational Phase 2 50-18-0, 6055-19-2 2907
34
Sargramostim Approved, Investigational Phase 2,Phase 1 123774-72-1, 83869-56-1
35
Cisplatin Approved Phase 2 15663-27-1 2767 441203 84093
36
Vincristine Approved, Investigational Phase 2 2068-78-2, 57-22-7 5978
37
Etoposide Approved Phase 2 33419-42-0 36462
38
Methotrexate Approved Phase 2 1959-05-2, 59-05-2 126941
39
leucovorin Approved Phase 2 58-05-9 143 6006
40
Iodine Approved, Investigational Phase 1, Phase 2,Phase 2 7553-56-2 807
41
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 2 1177-87-3
42
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
43
Promethazine Approved, Investigational Phase 2 60-87-7 4927
44
Diphenhydramine Approved, Investigational Phase 2 147-24-0, 58-73-1 3100
45
Acetaminophen Approved Phase 2 103-90-2 1983
46
Calcium Approved, Nutraceutical Phase 2,Phase 1 7440-70-2 271
47
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
48 Dermatologic Agents Phase 2,Phase 1
49 Anti-Infective Agents Phase 1, Phase 2,Phase 2
50 Anti-HIV Agents Phase 1, Phase 2,Phase 2

Interventional clinical trials:

(show all 39)
# Name Status NCT ID Phase Drugs
1 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
2 Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors Completed NCT00369785 Phase 3 donepezil hydrochloride;Placebo
3 Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors Terminated NCT00031798 Phase 3 methylphenidate hydrochloride
4 Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma Completed NCT01977677 Phase 1, Phase 2 temozolomide;plerixafor
5 Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors Completed NCT00629889 Phase 2 levetiracetam;pregabalin
6 Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer Completed NCT00014573 Phase 2 carmustine;cisplatin;cyclophosphamide;paclitaxel
7 Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma Completed NCT00006258 Phase 2 cisplatin;cyclophosphamide;etoposide;methotrexate;vincristine sulfate
8 Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor Completed NCT00070161 Phase 2 donepezil hydrochloride
9 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Cancers Completed NCT00002752 Phase 1, Phase 2
10 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain Tumors Completed NCT00003478 Phase 1, Phase 2
11 Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer Active, not recruiting NCT00445965 Phase 2
12 Functional Magnetic Resonance Imaging and 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Treating Patients With Newly Diagnosed Brain Tumors Withdrawn NCT00005083 Phase 2
13 Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors Unknown status NCT00002647 Phase 1 verteporfin
14 RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma Completed NCT01119599 Phase 1 Gamma-Secretase Inhibitor RO4929097;Temozolomide
15 Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction Completed NCT00030498 Phase 1 erlotinib hydrochloride
16 Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2 Completed NCT01082926 Phase 1
17 A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors Completed NCT00784914 Phase 1 temsirolimus
18 Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment Completed NCT00544284 Phase 1 bortezomib;temozolomide
19 Monoclonal Antibody Therapy in Treating Patients With Recurrent Gliomas Completed NCT00002753 Phase 1
20 Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent Cancer Completed NCT00006368 Phase 1
21 CC-5013 in Treating Patients With Recurrent Glioma Completed NCT00036894 Phase 1 lenalidomide
22 Calcitriol Plus Carboplatin in Treating Patients With Advanced Solid Tumors Completed NCT00008086 Phase 1 carboplatin
23 Thalidomide and Docetaxel in Treating Patients With Advanced Cancer Completed NCT00049296 Phase 1 docetaxel;thalidomide
24 MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma Completed NCT00020579 Phase 1 entinostat
25 Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory Lymphomas Completed NCT00019019 Phase 1 carboxyamidotriazole;paclitaxel
26 Carmustine in Treating Patients With Recurrent Malignant Glioma Completed NCT00004028 Phase 1 carmustine
27 Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal Cancer Completed NCT00003022 Phase 1
28 Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors Terminated NCT00110032 Phase 1 EF5
29 Gene Therapy and Chemotherapy in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma Terminated NCT00003567 Phase 1 O6-benzylguanine;carmustine;temozolomide
30 Study of Blood and Cheek Cell Samples From Patients With Glioma Completed NCT01009307
31 Study of Tissue Samples From Patients With Glioma or Other Brain Tumors Completed NCT00967200
32 Decision Making About Participating in Pharmacokinetic Studies in Patients Enrolled in a Phase I Treatment Clinical Trial Completed NCT00890435
33 Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors Completed NCT00499798
34 Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders Completed NCT00255671
35 Magnetic Resonance Imaging in Determining Extent of Cancer in Patients With Newly Diagnosed Glioma Completed NCT00005082 Not Applicable
36 Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases Terminated NCT02967380 Not Applicable Gadobenate Dimeglumine;Gadobutrol
37 Yoga Therapy in Treating Patients With Malignant Brain Tumors Terminated NCT01234805 Not Applicable
38 Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors Withdrawn NCT02194452 Not Applicable
39 Perfusion Magnetic Resonance Imaging in Measuring the Growth of Blood Vessels in Newly Diagnosed Brain Tumors Withdrawn NCT00005790 Not Applicable

Search NIH Clinical Center for Adult Ependymoblastoma

Genetic Tests for Adult Ependymoblastoma

Anatomical Context for Adult Ependymoblastoma

MalaCards organs/tissues related to Adult Ependymoblastoma:

42
Brain, Bone, Liver, Kidney, Bone Marrow, T Cells

Publications for Adult Ependymoblastoma

Variations for Adult Ependymoblastoma

Expression for Adult Ependymoblastoma

Search GEO for disease gene expression data for Adult Ependymoblastoma.

Pathways for Adult Ependymoblastoma

GO Terms for Adult Ependymoblastoma

Sources for Adult Ependymoblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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