MCID: ADL069
MIFTS: 20

Adult Intestinal Botulism

Categories: Eye diseases, Gastrointestinal diseases, Infectious diseases, Neuronal diseases, Rare diseases
Data Licensing
For inquiries, contact:

Aliases & Classifications for Adult Intestinal Botulism

MalaCards integrated aliases for Adult Intestinal Botulism:

Name: Adult Intestinal Botulism 58
Adult Intestinal Toxin-Mediated Botulism 58
Adult Intestinal Colonization Botulism 58
Adult Intestinal Toxemia Botulism 58
Infant-Like Botulism 58

Characteristics:


Age Of Onset:

Adult 58

Age Of Death:

adult 58

Classifications:

Orphanet: 58  
Rare neurological diseases
Rare eye diseases
Rare infectious diseases


External Ids:

ICD10 via Orphanet 32 A05.1
Orphanet 58 ORPHA178487

Summaries for Adult Intestinal Botulism

Orphanet: 58 A very rare form of botulism, a rare acquired neuromuscular junction disease with descending flaccid paralysis caused by botulinum neurotoxins (BoNTs), and is due to intestinal colonization by Clostridium botulinum leading to toxin-mediated infection with toxemia.

MalaCards based summary: Adult Intestinal Botulism, also known as adult intestinal toxin-mediated botulism, is related to intestinal botulism and toxin-mediated infectious botulism. Affiliated tissues include eye and brain, and related phenotypes are ptosis and diplopia

Related Diseases for Adult Intestinal Botulism

Diseases in the Intestinal Botulism family:

Adult Intestinal Botulism

Diseases related to Adult Intestinal Botulism via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 intestinal botulism 11.3
2 toxin-mediated infectious botulism 11.2
3 adult syndrome 10.2
4 wound botulism 10.2
5 infant botulism 10.2
6 crohn's disease 10.2
7 foodborne botulism 10.0
8 short bowel syndrome 10.0

Graphical network of the top 20 diseases related to Adult Intestinal Botulism:



Diseases related to Adult Intestinal Botulism

Symptoms & Phenotypes for Adult Intestinal Botulism

Human phenotypes related to Adult Intestinal Botulism:

58 30 (show all 9)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 ptosis 58 30 Hallmark (90%) Very frequent (99-80%)
HP:0000508
2 diplopia 58 30 Hallmark (90%) Very frequent (99-80%)
HP:0000651
3 cranial nerve paralysis 58 30 Hallmark (90%) Very frequent (99-80%)
HP:0006824
4 cerebral palsy 58 30 Hallmark (90%) Very frequent (99-80%)
HP:0100021
5 diaphragmatic paralysis 58 30 Hallmark (90%) Very frequent (99-80%)
HP:0006597
6 respiratory insufficiency due to muscle weakness 58 30 Frequent (33%) Frequent (79-30%)
HP:0002747
7 dyspnea 58 30 Frequent (33%) Frequent (79-30%)
HP:0002094
8 diarrhea 58 30 Frequent (33%) Frequent (79-30%)
HP:0002014
9 muscle weakness 58 Very frequent (99-80%)

Drugs & Therapeutics for Adult Intestinal Botulism

Search Clinical Trials, NIH Clinical Center for Adult Intestinal Botulism

Genetic Tests for Adult Intestinal Botulism

Anatomical Context for Adult Intestinal Botulism

Organs/tissues related to Adult Intestinal Botulism:

MalaCards : Eye, Brain

Publications for Adult Intestinal Botulism

Articles related to Adult Intestinal Botulism:

(show all 14)
# Title Authors PMID Year
1
Regulatory Networks Controlling Neurotoxin Synthesis in Clostridium botulinum and Clostridium tetani. 62
35737025 2022
2
Adult Intestinal Toxemia Botulism in a Patient With Crohn's Disease. 62
34977262 2022
3
Effects of antibiotics on the viability of and toxin production by Clostridium botulinum. 62
34219270 2021
4
Clinical Guidelines for Diagnosis and Treatment of Botulism, 2021. 62
33956777 2021
5
Adult Intestinal Toxemia Botulism. 62
31991691 2020
6
Adult Intestinal Botulism: A Rare Presentation in an Immunocompromised Patient With Short Bowel Syndrome. 62
30225463 2018
7
Identification of Cross Reactive Antigens of C. botulinum Types A, B, E & F by Immunoproteomic Approach. 62
29332140 2018
8
A Case of Adult Intestinal Toxemia Botulism During Prolonged Hospitalization in an Allogeneic Hematopoietic Cell Transplant Recipient. 62
29293935 2017
9
Adult intestinal colonization botulism mimicking brain death. 62
28500638 2017
10
Intestinal toxemia botulism in 3 adults, Ontario, Canada, 2006-2008. 62
22257757 2012
11
[Practice of botulism]. 62
21747147 2011
12
Intestinal toxemia botulism in Italy, 1984-2005. 62
17516104 2007
13
Botulism. 62
16163636 2005
14
Classic and emergent forms of botulism: the current status in Italy. 62
12631918 1999

Variations for Adult Intestinal Botulism

Expression for Adult Intestinal Botulism

Search GEO for disease gene expression data for Adult Intestinal Botulism.

Pathways for Adult Intestinal Botulism

GO Terms for Adult Intestinal Botulism

Sources for Adult Intestinal Botulism

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 24-Oct-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....