MCID: ADL014
MIFTS: 25

Adult Mesoblastic Nephroma

Categories: Cancer diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Adult Mesoblastic Nephroma

MalaCards integrated aliases for Adult Mesoblastic Nephroma:

Name: Adult Mesoblastic Nephroma 12 15
Benign Mixed Epithelial and Stromal Tumor of Kidney 73
Mixed Epithelial and Stromal Tumour of Kidney 12
Benign Mest 12
Mest 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2678
SNOMED-CT 68 388985009
UMLS 73 C1272677

Summaries for Adult Mesoblastic Nephroma

Disease Ontology : 12 A mixed neoplasm that is seen mostly in early infancy and that consists of classic and cellular (atypical) variants.

MalaCards based summary : Adult Mesoblastic Nephroma, also known as benign mixed epithelial and stromal tumor of kidney, is related to silver-russell syndrome and arts syndrome, and has symptoms including flank pain An important gene associated with Adult Mesoblastic Nephroma is NTRK3 (Neurotrophic Receptor Tyrosine Kinase 3). Affiliated tissues include kidney, and related phenotypes are Decreased shRNA abundance and Decreased shRNA abundance

Related Diseases for Adult Mesoblastic Nephroma

Diseases in the Adult Mesoblastic Nephroma family:

Congenital Mesoblastic Nephroma

Diseases related to Adult Mesoblastic Nephroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
# Related Disease Score Top Affiliating Genes
1 silver-russell syndrome 11.2
2 arts syndrome 11.0
3 diabetes mellitus, transient neonatal, 1 11.0
4 retinitis pigmentosa 4 11.0
5 childhood-onset schizophrenia 11.0
6 cystic nephroma 11.0
7 mixed epithelial stromal tumour 11.0
8 hepatosplenic t-cell lymphoma 10.0
9 connective tissue cancer 10.0 CD34 NTRK3
10 pediatric fibrosarcoma 10.0 ETV6 NTRK3
11 cellular congenital mesoblastic nephroma 10.0 ETV6 NTRK3
12 angiomyolipoma 10.0
13 congenital fibrosarcoma 10.0 ETV6 NTRK3
14 adult fibrosarcoma 10.0 ETV6 NTRK3
15 congenital mesoblastic nephroma 9.9 ETV6 NTRK3
16 breast secretory carcinoma 9.9 ETV6 NTRK3
17 acinar cell carcinoma 9.9 ETV6 NTRK3
18 malignant mesenchymoma 9.9 ETV6 NTRK3
19 hepatocellular carcinoma 9.8
20 autism 9.8
21 lung cancer susceptibility 3 9.8
22 diabetes mellitus 9.8
23 male infertility 9.8
24 gestational diabetes 9.8
25 adenocarcinoma 9.8
26 infertility 9.8
27 neuronitis 9.8
28 glioma 9.8
29 differentiated thyroid carcinoma 9.8 ETV6 NTRK3
30 precursor t-cell acute lymphoblastic leukemia 9.8 CD34 ETV6
31 acute leukemia 9.8 CD34 ETV6
32 bone marrow cancer 9.7 CD34 ETV6
33 gastrointestinal stromal tumor 9.7 CD34 NTRK3
34 nephrogenic adenofibroma 9.7 CD34 CHL1
35 fibrosarcoma 9.7 ETV6 NTRK3
36 peripheral nervous system neoplasm 9.6 CD34 CHL1
37 leukemia, chronic myeloid 9.5 CD34 ETV6
38 hematologic cancer 9.2 CD34 ETV6

Graphical network of the top 20 diseases related to Adult Mesoblastic Nephroma:



Diseases related to Adult Mesoblastic Nephroma

Symptoms & Phenotypes for Adult Mesoblastic Nephroma

UMLS symptoms related to Adult Mesoblastic Nephroma:


flank pain

GenomeRNAi Phenotypes related to Adult Mesoblastic Nephroma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance GR00251-A-1 9.4 NTRK3 CD34 CHL1
2 Decreased shRNA abundance GR00251-A-2 9.4 NTRK3 CD34 CHL1

Drugs & Therapeutics for Adult Mesoblastic Nephroma

Search Clinical Trials , NIH Clinical Center for Adult Mesoblastic Nephroma

Genetic Tests for Adult Mesoblastic Nephroma

Anatomical Context for Adult Mesoblastic Nephroma

MalaCards organs/tissues related to Adult Mesoblastic Nephroma:

41
Kidney

Publications for Adult Mesoblastic Nephroma

Articles related to Adult Mesoblastic Nephroma:

# Title Authors Year
1
Multiphasic contrast-enhanced CT and MRI findings of adult mesoblastic nephroma: A report of two cases. ( 23986620 )
2013
2
Mixed epithelial and stromal tumor of the kidney or adult mesoblastic nephroma: an update. ( 20845287 )
2010
3
Adult mesoblastic nephroma: a case with fatal recurrence. ( 18592471 )
2008
4
Adult mesoblastic nephroma: appearances on magnetic resonance imaging. ( 15288147 )
2004
5
Adult mesoblastic nephroma. ( 10707372 )
2000
6
Adult mesoblastic nephroma with ciliated epithelium. A case report. ( 10782471 )
2000
7
Adult mesoblastic nephroma: expansion of the morphologic spectrum and review of literature. ( 9669345 )
1998
8
A case of adult mesoblastic nephroma: ultrastructure and discussion of histogenesis. ( 2160549 )
1990

Variations for Adult Mesoblastic Nephroma

Expression for Adult Mesoblastic Nephroma

Search GEO for disease gene expression data for Adult Mesoblastic Nephroma.

Pathways for Adult Mesoblastic Nephroma

GO Terms for Adult Mesoblastic Nephroma

Biological processes related to Adult Mesoblastic Nephroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell differentiation GO:0030154 9.33 CHL1 ETV6 NTRK3
2 neuron migration GO:0001764 8.96 CHL1 NTRK3
3 hematopoietic stem cell proliferation GO:0071425 8.62 CD34 ETV6

Sources for Adult Mesoblastic Nephroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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