MCID: ADL056
MIFTS: 15

Adult Pineal Parenchymal Tumor

Categories: Cancer diseases

Aliases & Classifications for Adult Pineal Parenchymal Tumor

MalaCards integrated aliases for Adult Pineal Parenchymal Tumor:

Name: Adult Pineal Parenchymal Tumor 12 15 70
Adult Pineal Parenchymal Neoplasm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5031
NCIt 50 C8273
UMLS 70 C0280794

Summaries for Adult Pineal Parenchymal Tumor

MalaCards based summary : Adult Pineal Parenchymal Tumor, also known as adult pineal parenchymal neoplasm, is related to pineal parenchymal tumor of intermediate differentiation and hydrolethalus syndrome 1. An important gene associated with Adult Pineal Parenchymal Tumor is ZNF789 (Zinc Finger Protein 789). The drugs Immunoglobulins and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include pineal and liver.

Related Diseases for Adult Pineal Parenchymal Tumor

Diseases related to Adult Pineal Parenchymal Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 pineal parenchymal tumor of intermediate differentiation 9.8 ZNF789 ACOT6
2 hydrolethalus syndrome 1 9.5 PDE4DIP NBPF26
3 adult pineoblastoma 8.5 ZNF789 SEC22B PDE4DIP NBPF26 DCHS2 ACOT6

Symptoms & Phenotypes for Adult Pineal Parenchymal Tumor

Drugs & Therapeutics for Adult Pineal Parenchymal Tumor

Drugs for Adult Pineal Parenchymal Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Immunoglobulins Phase 1, Phase 2
2 Immunologic Factors Phase 1, Phase 2
3 Antibodies Phase 1, Phase 2
4 Antibodies, Monoclonal Phase 1, Phase 2
5
Carmustine Approved, Investigational Phase 1 154-93-8 2578
6
Irinotecan Approved, Investigational Phase 1 97682-44-5, 100286-90-6 60838
7
Iodine Approved, Investigational Phase 1 7553-56-2 807
8
Parathyroid hormone Approved, Investigational Phase 1 9002-64-6
9
Cadexomer iodine Experimental Phase 1 94820-09-4
10
Entinostat Investigational Phase 1 209783-80-2
11 topoisomerase I inhibitors Phase 1
12 Alkylating Agents Phase 1
13 Cola Phase 1
14 Liver Extracts Phase 1
15 Histone Deacetylase Inhibitors Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Phase I Study of At-Labeled Anti-Tenascin Human/Mouse Chimeric Monoclonal Antibody 81C6 (ch81C6) Via Surgically Created Cystic Resection Cavity in the Treatment of Patients With Primary or Metastatic Brain Tumors Completed NCT00003461 Phase 1, Phase 2
2 Phase I Pilot Study of Stereotaxic Radiosurgery in Patients With Intracranial Neoplasms Completed NCT00019578 Phase 1
3 Phase I Study of Anti-Tenascin Monoclonal Antibody I-Labeled 81C6 Via Surgically Created Cystic Resection Cavity in the Treatment of Patients With Primary Brain Tumors After External Beam Radiotherapy Completed NCT00003484 Phase 1 carmustine;irinotecan hydrochloride
4 A Phase I Study of an Oral Histone Deacetylase Inhibitor, MS-275, in Refractory Solid Tumors and Lymphomas Completed NCT00020579 Phase 1 entinostat
5 A Population Based Study of Genetic Predisposition and Gene-Environment Interactions in Cancer in East Anglia, Trent and West Midlands Unknown status NCT00757614
6 A Pharmacokinetic Participation Questionnaire Study Completed NCT00890435
7 Perfusion Magnetic Resonance Imaging of Brain Tumors: Correlation With Indicators of Angiogenesis Withdrawn NCT00005790

Search NIH Clinical Center for Adult Pineal Parenchymal Tumor

Genetic Tests for Adult Pineal Parenchymal Tumor

Anatomical Context for Adult Pineal Parenchymal Tumor

MalaCards organs/tissues related to Adult Pineal Parenchymal Tumor:

40
Pineal, Liver

Publications for Adult Pineal Parenchymal Tumor

Variations for Adult Pineal Parenchymal Tumor

Expression for Adult Pineal Parenchymal Tumor

Search GEO for disease gene expression data for Adult Pineal Parenchymal Tumor.

Pathways for Adult Pineal Parenchymal Tumor

GO Terms for Adult Pineal Parenchymal Tumor

Sources for Adult Pineal Parenchymal Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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