ARDS
MCID: ADL010
MIFTS: 64

Adult Respiratory Distress Syndrome (ARDS)

Categories: Blood diseases, Cardiovascular diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Adult Respiratory Distress Syndrome

MalaCards integrated aliases for Adult Respiratory Distress Syndrome:

Name: Adult Respiratory Distress Syndrome 39 12 15
Respiratory Distress Syndrome, Adult 77 45 74
Ards 12 15 64
Non-Cardiogenic Pulmonary Edema 12 74
Respiratory Distress Syndrome Adult 56
Shock Lung 12
Adult Rds 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11394
MeSH 45 D012128
NCIt 51 C3353
SNOMED-CT 69 67782005
ICD10 34 J80

Summaries for Adult Respiratory Distress Syndrome

PubMed Health : 64 About ards: ARDS, or acute respiratory distress syndrome, is a lung condition that leads to low oxygen levels in the blood. ARDS can be life threatening because your body's organs need oxygen-rich blood to work well.People who develop ARDS often are very ill with another disease or have major injuries. They might already be in the hospital when they develop ARDS.

MalaCards based summary : Adult Respiratory Distress Syndrome, also known as respiratory distress syndrome, adult, is related to acute respiratory distress syndrome and respiratory distress syndrome in premature infants, and has symptoms including dyspnea, respiratory distress and apnea. An important gene associated with Adult Respiratory Distress Syndrome is ELANE (Elastase, Neutrophil Expressed), and among its related pathways/superpathways are Toll-like Receptor Signaling Pathway and Allograft rejection. The drugs Midazolam and Propofol have been mentioned in the context of this disorder. Affiliated tissues include Lung and Lung, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Disease Ontology : 12 A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.

Wikipedia : 77 Acute respiratory distress syndrome (ARDS) is a type of respiratory failure characterized by rapid onset... more...

Related Diseases for Adult Respiratory Distress Syndrome

Diseases in the Adult Respiratory Distress Syndrome family:

Acute Respiratory Distress Syndrome Adult Acute Respiratory Distress Syndrome

Diseases related to Adult Respiratory Distress Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 428)
# Related Disease Score Top Affiliating Genes
1 acute respiratory distress syndrome 32.2 CXCL8 ELANE IL6 SFTPB SFTPC TNF
2 respiratory distress syndrome in premature infants 31.9 SFTPB SFTPC
3 disseminated intravascular coagulation 30.4 ELANE F2 SERPINE1
4 acute pyelonephritis 30.4 CXCL8 IL10 IL6
5 typhoid fever 30.4 F2 IL6 TNF
6 arthritis 30.4 CXCL8 IL10 IL6 TNF
7 pulmonary edema 30.4 ACE CXCL8 F2 IL10 TNF
8 pustular psoriasis 30.3 ELANE TNF
9 cardiogenic shock 30.2 IL6 TNF
10 acute pancreatitis 30.2 CXCL8 ELANE IL10 IL6
11 spotted fever 30.2 F2 IL10 TNF
12 acquired immunodeficiency syndrome 30.2 IL10 IL6 TNF
13 bacterial pneumonia 30.2 CXCL8 ELANE IL6 SFTPB
14 aseptic meningitis 30.2 CXCL8 IL10 TNF
15 pyelonephritis 30.2 ACE CXCL8 IL10 IL6 TNF
16 malaria 30.2 ANGPT2 CXCL8 IL10 IL6 TNF
17 avian influenza 30.1 CXCL8 IL6 TNF
18 q fever 30.1 IL10 IL6 TNF
19 capillary leak syndrome 30.1 C4A CXCL8 ELANE IL6
20 chorioamnionitis 30.0 CXCL8 ELANE IL6 TNF
21 pertussis 30.0 IL10 IL6 TNF
22 bronchiolitis 30.0 CXCL8 IL10 IL6 TNF
23 bronchiolitis obliterans 30.0 CXCL8 IL10 IL6 TNF
24 meningitis 30.0 CXCL8 IL10 IL6 TNF
25 chlamydia 30.0 CXCL8 IL10 IL6 TNF
26 pneumonia 30.0 CXCL8 ELANE IL10 IL6 SFTPB SFTPC
27 plasmodium vivax malaria 30.0 ANGPT2 IL10 IL6 TNF
28 kawasaki disease 30.0 ELANE IL10 IL6 TNF
29 hematopoietic stem cell transplantation 29.9 IL10 IL6 TNF
30 intracranial hypertension 29.9 F2 SERPINE1 TNF
31 diabetes mellitus 29.9 ACE C4A IL6 SERPINE1 TNF
32 toxoplasmosis 29.9 IL10 IL6 TNF
33 extrinsic allergic alveolitis 29.9 CXCL8 IL10 IL6
34 bacterial sepsis 29.8 CXCL8 ELANE IL10 TNF
35 surfactant dysfunction 29.8 SFTPB SFTPC
36 bronchopulmonary dysplasia 29.8 CXCL8 ELANE SFTPB
37 aspergillosis 29.8 ELANE IL10 TNF
38 myocardial infarction 29.6 ACE F2 IL10 IL6 SERPINE1 TNF
39 endocarditis 29.6 CXCL8 F2 IL10 IL6 TNF
40 leptospirosis 29.6 CXCL8 F2 IL10 IL6 TNF
41 peritonitis 29.6 CXCL8 F2 IL10 IL6 TNF
42 hemorrhagic fever 29.6 F2 IL10 IL6 TNF
43 respiratory failure 29.6 ACE CXCL8 ELANE SFTPB SFTPC TNF
44 cholangitis 29.4 F2 IL6 TNF
45 dengue hemorrhagic fever 29.4 CXCL8 F2 IL10 IL6 TNF
46 pulmonary fibrosis, idiopathic 29.4 CXCL8 ELANE SFTPB SFTPC TNF
47 systemic lupus erythematosus 29.0 ACE C4A C5 ELANE F2 IL10
48 lung disease 28.2 CXCL8 ELANE ELN IL10 IL6 SFTPB
49 refsum disease, classic 11.8
50 pulmonary edema of mountaineers 11.5

Graphical network of the top 20 diseases related to Adult Respiratory Distress Syndrome:



Diseases related to Adult Respiratory Distress Syndrome

Symptoms & Phenotypes for Adult Respiratory Distress Syndrome

UMLS symptoms related to Adult Respiratory Distress Syndrome:


dyspnea, respiratory distress, apnea, hemoptysis, cheyne-stokes respiration, coughing, hoarseness, labored breathing

GenomeRNAi Phenotypes related to Adult Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.7 ACE CXCL8 F2 IL10 SERPINB2 TNF
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.7 ACE CXCL8 F2 IL10 SERPINB2 TNF

MGI Mouse Phenotypes related to Adult Respiratory Distress Syndrome:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.1 ACE ANGPT2 C5 ELANE F2 IL10
2 immune system MP:0005387 10.03 ACE ANGPT2 C5 ELANE F2 IL10
3 cardiovascular system MP:0005385 9.97 ACE ANGPT2 F2 IL10 IL6 SERPINE1
4 mortality/aging MP:0010768 9.97 ACE ANGPT2 C5 ELANE F2 IL10
5 neoplasm MP:0002006 9.56 ACE ELANE IL10 IL6 SERPINB2 SERPINE1
6 respiratory system MP:0005388 9.28 ANGPT2 C5 F2 IL10 IL6 SERPINE1

Drugs & Therapeutics for Adult Respiratory Distress Syndrome

PubMedHealth treatment related to Adult Respiratory Distress Syndrome: 64

ARDS is treated in a hospital's intensive care unit. Current treatment approaches focus on improving blood oxygen levels and providing supportive care. Doctors also will try to pinpoint and treat the underlying cause of the condition.

Drugs for Adult Respiratory Distress Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 513)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Midazolam Approved, Illicit Phase 4,Phase 3,Not Applicable 59467-70-8 4192
2
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Not Applicable 2078-54-8 4943
3
Remifentanil Approved Phase 4,Not Applicable,Early Phase 1 132875-61-7 60815
4
Cisatracurium Approved Phase 4,Phase 3,Early Phase 1 96946-41-7
5
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
6
Hydrocortisone acetate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-03-3
7
Racepinephrine Approved Phase 4,Phase 3,Phase 2 329-65-7 838
8
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-23-7 5754
9
Budesonide Approved Phase 4,Phase 2,Not Applicable 51333-22-3 63006 5281004
10 Beractant Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 108778-82-1
11 Poractant alfa Approved Phase 4,Phase 2,Phase 3,Not Applicable 129069-19-8
12
Acetaminophen Approved Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1 103-90-2 1983
13
Clonidine Approved Phase 4 4205-90-7 2803
14
Tramadol Approved, Investigational Phase 4,Not Applicable 27203-92-5 33741
15
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
16
Sufentanil Approved, Investigational Phase 4,Early Phase 1 56030-54-7 41693
17
Nefopam Approved, Investigational Phase 4 13669-70-0
18
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 83-43-2 6741
19
Methylprednisolone hemisuccinate Approved Phase 4,Phase 2,Phase 3,Not Applicable 2921-57-5
20
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 302-25-0
21
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 50-24-8 5755
22
Povidone-iodine Approved Phase 4,Phase 3,Phase 2 25655-41-8
23
Metformin Approved Phase 4,Phase 2,Phase 3,Not Applicable 657-24-9 14219 4091
24
Atracurium Approved, Experimental, Investigational Phase 4,Not Applicable 64228-79-1 47319
25
Carbon monoxide Approved, Investigational Phase 4,Phase 2,Phase 1 630-08-0 281
26
Atropine Approved, Vet_approved Phase 4,Phase 1,Not Applicable 51-55-8, 5908-99-6 174174
27
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 94-09-7, 1994-09-7 2337
28
tannic acid Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 1401-55-4
29
Desflurane Approved Phase 4,Not Applicable 57041-67-5 42113
30
Ketamine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 6740-88-1 3821
31
Progesterone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 57-83-0 5994
32
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 378-44-9 9782
33
Zinc Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 7440-66-6 32051
34
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 1177-87-3
35
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-02-2 5743
36
Morphine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 57-27-2 5288826
37
Sevoflurane Approved, Vet_approved Phase 4,Not Applicable,Early Phase 1 28523-86-6 5206
38
Rocuronium Approved Phase 4,Not Applicable,Early Phase 1 119302-91-9, 143558-00-3 441290
39
Succinylcholine Approved Phase 4 306-40-1 5314
40
Cetrorelix Approved, Investigational Phase 4 120287-85-6 25074887 16129715
41
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1 113775-47-6 68602 5311068
42
Nifedipine Approved Phase 4,Phase 3,Not Applicable 21829-25-4 4485
43
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 1,Not Applicable,Early Phase 1 437-38-7 3345
44
Sodium Citrate Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 68-04-2
45
Iron Approved, Experimental Phase 4 7439-89-6, 15438-31-0 23925 27284
46
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
47
Cefuroxime Approved Phase 4 55268-75-2 5361202 5479529
48
Metronidazole Approved Phase 4,Phase 2,Phase 3,Not Applicable 443-48-1 4173
49
Labetalol Approved Phase 4 36894-69-6 3869
50
Misoprostol Approved Phase 4,Not Applicable 59122-46-2 5282381

Interventional clinical trials:

(show top 50) (show all 1346)
# Name Status NCT ID Phase Drugs
1 Propofol Versus Midazolam as Premedication for Preterm Neonates With Respiratory Distress Syndrome (RDS) Unknown status NCT00797160 Phase 4 propofol
2 Impact of Fluid Resuscitation Therapy on Pulmonary Edema as Measured by Alveolar Fluid Clearance in Patients With Acute Respiratory Distress Syndrome (ARDS) Unknown status NCT01763853 Phase 4 4% albumin
3 Efficacy Evaluation of Surfactant Administration Via Laryngeal Mask Airway Unknown status NCT01173237 Phase 4
4 Effects of Neuromuscular Blocking Agents (NMBA) on the Alteration of Transpulmonary Pressures at the Early Phase of Acute Respiratory Distress Syndrome (ARDS) Unknown status NCT01573715 Phase 4 NIMBEX;NIMBEX
5 Early CPAP in Respiratory Distress Syndrome Unknown status NCT00368680 Phase 4
6 Effect of Treatment With Stress-Doses Glucocorticoid in Patients With Acute Respiratory Distress Syndrome (ARDS) Unknown status NCT00773058 Phase 4 hydrocortisone;placebo
7 Two Strategies of RDS Treatment in Newborns With Birth Weight > 1500 Grams Unknown status NCT00277030 Phase 4 Surfactant
8 SLI MANEUVER and RESPIRATORY MORBIDITIES Unknown status NCT02887924 Phase 4
9 Prevention of Chronic Lung Disease (CLD) in Preterm Infants Unknown status NCT00883532 Phase 4 budesonide;surfactant and air (placebo)
10 Brain Oxygenation and Function of Preterm Newborns During Administration of Two Different Surfactant Preparations Unknown status NCT01941524 Phase 4 Poractant alfa instillation;Beractant instillation
11 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
12 Surfactant Administration During Spontaneous Breathing Unknown status NCT01329432 Phase 4
13 The Study of Using Esophageal Pressure to Guide the PEEP Setting in Abdominal Hypertension Patients Who Undergoing Mechanical Ventilation Unknown status NCT01825304 Phase 4
14 6-Methyl-Prednisolone for Multiple Organ Dysfunction Syndrome Unknown status NCT00127985 Phase 4 6-methyl-prednisolone
15 Withholding Feeds During Red Blood Cell Transfusion and TRAGI Unknown status NCT02132819 Phase 4
16 Neurally Adjusted Ventilatory Assist (NAVA) vs. Pressure Support in Pediatric Acute Respiratory Failure Unknown status NCT01873521 Phase 4
17 FRC Guided Therapy in Acute Respiratory Failure Unknown status NCT01280019 Phase 4
18 Cervical Cerclage for Preventing Spontaneous Preterm Birth in Singleton Pregnancies Without Prior Spontaneous Preterm Birth and With Short Transvaginal Ultrasound Cervical Length Unknown status NCT02746900 Phase 4
19 Preventing Recurrent Gestational Diabetes With Metformin Unknown status NCT02394158 Phase 4 Metformin;placebo
20 Treatment of Intracranial Hypertension of Severe Tramatic Brain Injured Patients. Physiopathologic Effects of Neuromuscular Blocking Agents Unknown status NCT02404779 Phase 4 cisatracurium besilate
21 Comparison of Nasal CPAP and Nasal SIMV in Transient Tachypnea of Newborn Unknown status NCT01499238 Phase 4
22 Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory Failure. Unknown status NCT00331656 Phase 4
23 Corticosteroid Mediates Acute Respiratory Distress Syndrome Completed NCT02819453 Phase 4 Methylprednisolone
24 Efficacy Study of Dexamethasone to Treat the Acute Respiratory Distress Syndrome Completed NCT01731795 Phase 4 Dexamethasone
25 Remifentanil Versus Morphine for Sedation of Premature Neonates With Respiratory Distress Syndrome Completed NCT00391105 Phase 4 Remifentanil
26 Study of Sivelestat Sodium Hydrate in Acute Lung Injury (ALI) Associated With Systemic Inflammatory Response Syndrome (SIRS) in Japan Completed NCT00219375 Phase 4 Sivelestat sodium hydrate;Sivelestat sodium hydrate
27 Effects of Bolus Surfactant Therapy on Peripheral Perfusion Index and Tissue Carbon Monoxide Completed NCT01923844 Phase 4 exogenous surfactant
28 Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study) Completed NCT01600651 Phase 4
29 Randomized Controlled Trial of Surfactant Delivery Via Laryngeal Mask Airway (LMA) Versus Endotracheal Intubation Completed NCT01042600 Phase 4
30 Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study) Completed NCT02166853 Phase 4 sevoflurane;midazolam
31 Efficacy of Combining Prophylactic Curosurf With Early Nasal CPAP in Delivery Room: the Curpap Study Completed NCT00501982 Phase 4 Poractant alfa (Curosurf®)
32 Comparison of Effectiveness of Nasal CPAP and Nasal IMV in Early Rescue Surfactant Treatment in Preterm Infants Completed NCT01741129 Phase 4
33 Premedication for Non-Emergency Endotracheal Intubation In the NICU Completed NCT01749501 Phase 4 Rocuronium
34 Synchronized Intermittent Mandatory Ventilation (SIMV) Versus Nasal Intermittent Positive Pressure Ventilation (NIPPV) In Preterm Infants With Respiratory Distress Completed NCT00486850 Phase 4
35 Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach Completed NCT02135146 Phase 4 Plasmalyte 3ml/kg/hr group;Plasmalyte 6ml/kg/hr group
36 Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery Completed NCT02635542 Phase 4 Succinylcholine;Cisatracurium
37 Inflammatory Response Secondary Using Intravenous Anesthesia Versus Inhalation Anesthesia With Halogenated Agents Completed NCT02168751 Phase 4 propofol;Sevoflurane
38 Effect of Perioperative Lung Protective Strategies on the Occurrence of Postoperative Pulmonary Complications in Patients Undergoing Lumbar Spinal Surgery in the Prone Position Completed NCT02373475 Phase 4
39 Effect Of Ketamine Infusion In Patients With COPD Applied One Lung Ventilation Completed NCT02962999 Phase 4 Ketamine;Saline
40 Vaginal Progesterone for Prevention of Preterm Labor in Asymptomatic Twin Pregnancies With Sonographic Short Cervix Completed NCT02338830 Phase 4 Progesterone
41 Steroids in Bilateral Total Knee Replacement Completed NCT01399268 Phase 4 Hydrocortisone;Saline
42 On Versus Off Pump Myocardial Revascularization Study Completed NCT01290952 Phase 4
43 Restrictive vs. Liberal Oxygen Therapy for Trauma Patients Completed NCT03491644 Phase 4 Titrated Oxygen;Liberal Oxygen
44 A Randomized Trial Comparing the Impact of One Versus Two Courses of Antenatal Steroids (ACS) on Neonatal Outcome Completed NCT00201643 Phase 4 Betamethasone or Dexamethasone (2nd course of ACS);Placebo
45 The Study of Pharmacokinetics and Pharmacodynamics of Cisatracurium Completed NCT03337373 Phase 4 cisatracurium
46 Non-Positive Pressure Ventilation in Hypoxemic Patients Completed NCT00925860 Phase 4
47 Efficacy of 17 Alpha-hydroxyprogesterones Caproate for the Prevention of Preterm Delivery Completed NCT00331695 Phase 4 17 alpha-hydroxyprogesterones caproate
48 Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation Completed NCT03026777 Phase 4 intravenous crystalloid fluid, 500 mL
49 Recruitment Maneuver After Intubation Completed NCT01014299 Phase 4
50 Vasculopathic Injury and Plasma as Endothelial Rescue - OCTAplas Trial (EudraCT no. 2014-000452-28) Completed NCT02253082 Phase 4 OctaplasLG®

Search NIH Clinical Center for Adult Respiratory Distress Syndrome

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: respiratory distress syndrome, adult

Genetic Tests for Adult Respiratory Distress Syndrome

Anatomical Context for Adult Respiratory Distress Syndrome

MalaCards organs/tissues related to Adult Respiratory Distress Syndrome:

42
Lung, Brain, Liver, Heart, Neutrophil, Cervix, Testes
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Adult Respiratory Distress Syndrome:
# Tissue Anatomical CompartmentCell Relevance
1 Lung Alveoli Alveolar Epithelial Type 1 Cells Affected by disease, potential therapeutic candidate
2 Lung Alveoli Alveolar Epithelial Type 2 Cells Affected by disease, potential therapeutic candidate
3 Lung Pulmonary Capillary Plexus Affected by disease

Publications for Adult Respiratory Distress Syndrome

Articles related to Adult Respiratory Distress Syndrome:

(show top 50) (show all 1415)
# Title Authors Year
1
Use veno-venous extra corporeal membrane oxygenation in elderly patients with post-cardiotomy hypoxia: the changing paradigm of respiratory support in adult respiratory distress syndrome. ( 30642349 )
2019
2
Ventilatory setting in Adult Respiratory Distress Syndrome: Don't listen the sound of Sirens! But keep some dreams in your mind…. ( 30885316 )
2019
3
Machine treatment of adult respiratory distress syndrome: Rinse or wash cycle? ( 29102203 )
2018
4
Extracorporeal membrane oxygenation in the management of post-pneumonectomy air leak and adult respiratory distress syndrome of the non-operated lung. ( 28132594 )
2017
5
Neurologic Injury With Severe Adult Respiratory Distress Syndrome in Patients Undergoing Extracorporeal Membrane Oxygenation: A Single-Center Retrospective Analysis. ( 28863024 )
2017
6
Incidence of adult respiratory distress syndrome in trauma patients: A systematic review and meta-analysis over a period of three decades. ( 28590348 )
2017
7
Extracorporeal membrane oxygenation for adult respiratory distress syndrome in trauma patients: A case series and systematic literature review. ( 27779577 )
2017
8
H1N1 with adult respiratory distress syndrome for emergency lower segment cesarean section: A case report. ( 27375404 )
2016
9
Early initiation of extracorporeal membrane oxygenation improves survival in adult trauma patients with severe adult respiratory distress syndrome. ( 27032012 )
2016
10
Ambulatory Extracorporeal Membrane Oxygenation: A Surgical Innovation for Adult Respiratory Distress Syndrome. ( 26963436 )
2016
11
History of adult respiratory distress syndrome. ( 27155768 )
2016
12
A Case of Scrub Typhus Complicated by Adult Respiratory Distress Syndrome and Successful Management with Extracorporeal Membrane Oxygenation. ( 27458040 )
2016
13
Performance of Multiple Risk Assessment Tools to Predict Mortality for Adult Respiratory Distress Syndrome with Extracorporeal Membrane Oxygenation Therapy: An External Validation Study Based on Chinese Single-center Data. ( 27411456 )
2016
14
Validity of Outcome Prediction Scoring Systems in Korean Patients with Severe Adult Respiratory Distress Syndrome Receiving Extracorporeal Membrane Oxygenation Therapy. ( 27247503 )
2016
15
Adult respiratory distress syndrome. ( 27513791 )
2016
16
Coronavirus NL63-induced Adult Respiratory Distress Syndrome. ( 26720790 )
2016
17
A case of tension pneumothorax during hyperbaric oxygen therapy in an earthquake survivor with crush injury complicated by ARDS (adult respiratory distress syndrome). ( 26094299 )
2015
18
Severe adult respiratory distress syndrome from Goodpasture syndrome. Survival using extracorporeal membrane oxygenation. ( 25590156 )
2015
19
Boussignac CPAP system for brain death confirmation with apneic test in case of acute lung injury/adult respiratory distress syndrome - series of cases. ( 26124664 )
2015
20
External validation of scores proposed for estimation of survival probability of patients with severe adult respiratory distress syndrome undergoing extracorporeal membrane oxygenation therapy: a retrospective study. ( 25887616 )
2015
21
High tidal volume decreases adult respiratory distress syndrome, atelectasis, and ventilator days compared with low tidal volume in pediatric burned patients with inhalation injury. ( 25724604 )
2015
22
Rapid-onset adult respiratory distress syndrome after activated charcoal aspiration. A pitch-black tale of a potential to kill. ( 25635491 )
2015
23
Near drowning and adult respiratory distress syndrome. ( 25453852 )
2015
24
Adult respiratory distress syndrome following cardiac surgery. ( 24299028 )
2014
25
Ventilation during extracorporeal membrane oxygenation for adult respiratory distress syndrome. ( 25041935 )
2014
26
High-frequency oscillation in early adult respiratory distress syndrome. ( 25041589 )
2014
27
Near drowning and adult respiratory distress syndrome. ( 24642043 )
2014
28
Blood alcohol content, injury severity, and adult respiratory distress syndrome. ( 24854314 )
2014
29
Comparing surrogates of oxygenation and ventilation between airway pressure release ventilation and biphasic airway pressure in a mechanical model of adult respiratory distress syndrome. ( 24998370 )
2014
30
Adult respiratory distress syndrome risk factors for injured patients undergoing damage-control laparotomy: AAST multicenter post hoc analysis. ( 25248057 )
2014
31
Surgical lung biopsy to diagnose Behcet's vasculitis with adult respiratory distress syndrome. ( 25378849 )
2014
32
Surgical lung biopsy in adult respiratory distress syndrome: a meta-analysis. ( 25069683 )
2014
33
The Role of Corticosteroids in Adult Respiratory Distress Syndrome caused by Viridans Group Streptococci Bacteremia in Neutropenic Patients. ( 25237468 )
2014
34
Arthritis and adult respiratory distress syndrome: unusual presentations of typhoid fever. ( 25336548 )
2014
35
Risk stratification in critically ill patients: GDF-15 scores in adult respiratory distress syndrome. ( 23905849 )
2013
36
A case of vivax malaria complicated by adult respiratory distress syndrome and successful management with extracorporeal membrane oxygenation. ( 24327781 )
2013
37
High or conventional positive end-expiratory pressure in adult respiratory distress syndrome. ( 24290732 )
2013
38
Odontogenic infection leading to adult respiratory distress syndrome. ( 22871306 )
2013
39
Hitch-hiker taken for a ride: an unusual cause of myocarditis, septic shock and adult respiratory distress syndrome. ( 23314875 )
2013
40
The Adult Respiratory Distress Syndrome Cognitive Outcomes Study: long-term neuropsychological function in survivors of acute lung injury. ( 23714655 )
2013
41
Paracrine activity of stem cells in therapy for acute lung injury and adult respiratory distress syndrome. ( 23609289 )
2013
42
Adult respiratory distress syndrome induced by blunt trauma-A dying threat throughout the world? ( 24398078 )
2013
43
The adult respiratory distress syndrome cognitive outcomes study: long-term neuropsychological function in survivors of acute lung injury. ( 22492988 )
2012
44
Fresh frozen plasma/red blood cell resuscitation regimen that restores procoagulants without causing adult respiratory distress syndrome. ( 22491592 )
2012
45
Unmasking of tracheomalacia following short-term mechanical ventilation in a patient of adult respiratory distress syndrome. ( 22701211 )
2012
46
An innovative approach to predict the development of adult respiratory distress syndrome in patients with blunt trauma. ( 22914080 )
2012
47
Trends in caring for adult respiratory distress syndrome patients. ( 22475700 )
2012
48
Aseptic meningitis and adult respiratory distress syndrome caused by Borrelia persica. ( 22782695 )
2012
49
Mortality of patients with respiratory insufficiency and adult respiratory distress syndrome after surgery: the obesity paradox. ( 21778465 )
2012
50
The effect of hypoxia-hypercapnia on neuropsychological function in adult respiratory distress syndrome. ( 23250501 )
2012

Variations for Adult Respiratory Distress Syndrome

Expression for Adult Respiratory Distress Syndrome

Search GEO for disease gene expression data for Adult Respiratory Distress Syndrome.

Pathways for Adult Respiratory Distress Syndrome

Pathways related to Adult Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

(show all 33)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.1 ACE CXCL8 IL10 IL6 SERPINE1 TNF
2
Show member pathways
12.78 C4A C5 CXCL8 IL10 IL6 TNF
3
Show member pathways
12.52 ANGPT2 F2 IL10 IL6 TNF
4
Show member pathways
12.17 CXCL8 IL10 IL6 TNF
5
Show member pathways
12.17 F2 IL6 SERPINE1 SOD3 TNF
6
Show member pathways
12.16 CXCL8 IL6 SERPINE1 TNF
7 11.98 C4A CXCL8 IL10 IL6 TNF
8 11.94 C5 CXCL8 IL6 TNF
9 11.9 IL10 IL6 TNF
10 11.89 CXCL8 IL10 IL6 TNF
11 11.84 CXCL8 IL6 SERPINB2 SERPINE1
12 11.83 ANGPT2 IL6 SERPINE1
13 11.8 CXCL8 IL6 SERPINE1 TNF
14 11.78 CXCL8 IL6 TNF
15 11.76 CXCL8 IL10 IL6 TNF
16 11.7 C4A C5 F2 SERPINB2 SERPINE1
17 11.68 IL10 IL6 TNF
18 11.66 IL10 IL6 TNF
19 11.63 C4A C5 IL10
20
Show member pathways
11.6 CXCL8 IL6 TNF
21 11.53 CXCL8 IL6 TNF
22 11.46 ELANE IL6 TNF
23 11.33 IL10 IL6 TNF
24 11.31 CXCL8 IL10 IL6 TNF
25 11.3 IL10 IL6 TNF
26 11.25 CXCL8 IL10 IL6 TNF
27 11.19 IL10 IL6 TNF
28 11.15 CXCL8 ELN IL6 SFTPC TNF
29 11.03 ANGPT2 CXCL8 IL10 IL6 TNF
30 10.98 C4A C5 CXCL8 IL10 IL6 TNF
31 10.91 CXCL8 IL6 TNF
32 10.9 ANGPT2 CXCL8 ELN IL10 IL6 TNF
33 10.76 SERPINB2 SERPINE1

GO Terms for Adult Respiratory Distress Syndrome

Cellular components related to Adult Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.83 ACE ANGPT2 C4A C5 CXCL8 ELANE
2 collagen-containing extracellular matrix GO:0062023 9.62 ELANE ELN SERPINE1 SOD3
3 extracellular region GO:0005576 9.53 ACE ANGPT2 C4A C5 CXCL8 ELANE
4 lamellar body GO:0042599 9.26 SFTPB SFTPC
5 multivesicular body lumen GO:0097486 9.16 SFTPB SFTPC

Biological processes related to Adult Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

(show all 31)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.92 CXCL8 IL10 IL6 TNF
2 animal organ morphogenesis GO:0009887 9.82 ELN SFTPB TNF
3 positive regulation of DNA-binding transcription factor activity GO:0051091 9.81 IL10 IL6 TNF
4 regulation of complement activation GO:0030449 9.81 C4A C5 F2
5 positive regulation of angiogenesis GO:0045766 9.81 ANGPT2 C5 CXCL8 SERPINE1
6 negative regulation of endopeptidase activity GO:0010951 9.8 C4A C5 SERPINB2 SERPINE1
7 regulation of signaling receptor activity GO:0010469 9.8 CXCL8 F2 IL10 IL6 SERPINE1 TNF
8 response to glucocorticoid GO:0051384 9.73 IL10 IL6 TNF
9 positive regulation of smooth muscle cell proliferation GO:0048661 9.7 ELANE IL6 TNF
10 embryonic digestive tract development GO:0048566 9.65 CXCL8 TNF
11 cellular protein metabolic process GO:0044267 9.65 C4A F2 IL6 SFTPB SFTPC
12 positive regulation of glial cell proliferation GO:0060252 9.64 IL6 TNF
13 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.63 IL10 TNF
14 positive regulation of blood coagulation GO:0030194 9.62 F2 SERPINE1
15 response to molecule of bacterial origin GO:0002237 9.61 CXCL8 IL10
16 positive regulation of chemokine secretion GO:0090197 9.61 C5 TNF
17 negative regulation of fibrinolysis GO:0051918 9.6 F2 SERPINE1
18 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.59 ELANE TNF
19 negative regulation of lipid storage GO:0010888 9.58 IL6 TNF
20 endothelial cell apoptotic process GO:0072577 9.58 IL10 TNF
21 respiratory gaseous exchange GO:0007585 9.58 ELN SFTPB SFTPC
22 neutrophil mediated immunity GO:0002446 9.57 ACE IL6
23 negative regulation of cytokine secretion involved in immune response GO:0002740 9.55 IL10 TNF
24 positive regulation of neuroinflammatory response GO:0150078 9.54 IL6 TNF
25 fibrinolysis GO:0042730 9.54 F2 SERPINB2 SERPINE1
26 negative regulation of chemokine biosynthetic process GO:0045079 9.48 ELANE IL6
27 neutrophil mediated killing of gram-negative bacterium GO:0070945 9.46 ELANE F2
28 receptor biosynthetic process GO:0032800 9.43 IL10 TNF
29 inflammatory response GO:0006954 9.43 C4A C5 CXCL8 IL10 IL6 TNF
30 negative regulation of growth of symbiont in host GO:0044130 9.33 ELANE IL10 TNF
31 cellular response to lipopolysaccharide GO:0071222 9.02 CXCL8 IL10 IL6 SERPINE1 TNF

Molecular functions related to Adult Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 9.13 ELANE SERPINE1 TNF
2 cytokine activity GO:0005125 8.92 CXCL8 IL10 IL6 TNF

Sources for Adult Respiratory Distress Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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