MCID: ADL043
MIFTS: 22

Adult Type Testicular Granulosa Cell Tumor

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Adult Type Testicular Granulosa Cell Tumor

MalaCards integrated aliases for Adult Type Testicular Granulosa Cell Tumor:

Name: Adult Type Testicular Granulosa Cell Tumor 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:8394
NCIt 49 C39946
UMLS 71 C1515284

Summaries for Adult Type Testicular Granulosa Cell Tumor

MalaCards based summary : Adult Type Testicular Granulosa Cell Tumor is related to testicular granulosa cell tumor and gynandroblastoma. An important gene associated with Adult Type Testicular Granulosa Cell Tumor is THEM6 (Thioesterase Superfamily Member 6). Affiliated tissues include breast, testis and ovary.

Related Diseases for Adult Type Testicular Granulosa Cell Tumor

Diseases in the Testicular Granulosa Cell Tumor family:

Juvenile Type Testicular Granulosa Cell Tumor Adult Type Testicular Granulosa Cell Tumor

Diseases related to Adult Type Testicular Granulosa Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 178)
# Related Disease Score Top Affiliating Genes
1 testicular granulosa cell tumor 29.6 MLANA FOXL2 CALB2 AFP
2 gynandroblastoma 10.3 FOXL2 CALB2
3 mixed germ cell-sex cord neoplasm 10.3 FOXL2 CALB2
4 ovarian melanoma 10.2 MLANA CALB2
5 retroperitoneal sarcoma 10.2 MLANA CALB2
6 thymus clear cell carcinoma 10.2 MLANA CALB2
7 fallopian tube carcinosarcoma 10.2 NCAM1 CALB2
8 rete testis adenoma 10.2 NCAM1 CALB2
9 papillary thymic adenocarcinoma 10.2 NCAM1 CALB2
10 mediastinum sarcoma 10.2 NCAM1 CALB2
11 wolffian duct adenocarcinoma 10.2 ESR1 CALB2
12 ovarian serous adenofibroma 10.2 NCAM1 CALB2
13 ovarian serous cystadenofibroma 10.2 NCAM1 CALB2
14 intravascular fasciitis 10.1 MLANA ESR1
15 laryngeal small cell carcinoma 10.1 NCAM1 MLANA
16 glomangiomatosis 10.1 NCAM1 MLANA
17 diffuse peritoneal leiomyomatosis 10.1 PGR CALB2
18 olfactory nerve neoplasm 10.1 NCAM1 MLANA
19 testicular cancer 10.1
20 cranial nerve malignant neoplasm 10.1 NCAM1 MLANA
21 peritoneal benign neoplasm 10.1 PGR CALB2
22 granular cell tumor 10.1 MLANA CALB2
23 cardiovascular cancer 10.1 MLANA CALB2
24 cranial nerve neoplasm 10.1 NCAM1 MLANA
25 epithelial predominant wilms' tumor 10.1 NCAM1 MLANA
26 cervical serous adenocarcinoma 10.1 PGR MLANA
27 mucinous adenocarcinoma 10.0 PGR ESR1
28 glassy cell carcinoma of the cervix 10.0 PGR ESR1
29 bartholin's gland adenoid cystic carcinoma 10.0 PGR ESR1
30 chronic tympanitis 10.0 PGR ESR1
31 bartholin's gland adenoma 10.0 PGR ESR1
32 granulomatous endometritis 10.0 PGR ESR1
33 endometritis 10.0 PGR ESR1
34 bartholin's gland benign neoplasm 10.0 PGR ESR1
35 vestibular gland benign neoplasm 10.0 PGR ESR1
36 breast juvenile papillomatosis 10.0 PGR ESR1
37 lung leiomyoma 10.0 PGR ESR1
38 vulvar syringoma 10.0 PGR ESR1
39 trigonitis 10.0 PGR ESR1
40 breast scirrhous carcinoma 10.0 PGR ESR1
41 oncocytic breast carcinoma 10.0 PGR ESR1
42 ovarian seromucinous carcinoma 10.0 PGR ESR1
43 uterus leiomyosarcoma 10.0 PGR MLANA
44 breast papillary carcinoma 10.0 PGR ESR1
45 breast leiomyoma 10.0 PGR ESR1
46 intravenous leiomyomatosis 10.0 PGR ESR1
47 comedo carcinoma 10.0 PGR ESR1
48 breast metaplastic carcinoma 10.0 PGR ESR1
49 mammographic density 10.0 PGR ESR1
50 papillary serous adenocarcinoma 10.0 PGR CALB2

Graphical network of the top 20 diseases related to Adult Type Testicular Granulosa Cell Tumor:



Diseases related to Adult Type Testicular Granulosa Cell Tumor

Symptoms & Phenotypes for Adult Type Testicular Granulosa Cell Tumor

Drugs & Therapeutics for Adult Type Testicular Granulosa Cell Tumor

Search Clinical Trials , NIH Clinical Center for Adult Type Testicular Granulosa Cell Tumor

Genetic Tests for Adult Type Testicular Granulosa Cell Tumor

Anatomical Context for Adult Type Testicular Granulosa Cell Tumor

MalaCards organs/tissues related to Adult Type Testicular Granulosa Cell Tumor:

40
Breast, Testis, Ovary, Prostate, Thymus, Smooth Muscle, Liver

Publications for Adult Type Testicular Granulosa Cell Tumor

Articles related to Adult Type Testicular Granulosa Cell Tumor:

# Title Authors PMID Year
1
Response to antiangiogenesis therapy in a patient with advanced adult-type testicular granulosa cell tumor. 61
19777766 2009
2
Adult-type testicular granulosa cell tumor: case report and review of the literature. 61
17095056 2006
3
Granulosa cell tumor of the contralateral testis in a man with a history of cryptorchism. 61
14730174 2004

Variations for Adult Type Testicular Granulosa Cell Tumor

Expression for Adult Type Testicular Granulosa Cell Tumor

Search GEO for disease gene expression data for Adult Type Testicular Granulosa Cell Tumor.

Pathways for Adult Type Testicular Granulosa Cell Tumor

GO Terms for Adult Type Testicular Granulosa Cell Tumor

Biological processes related to Adult Type Testicular Granulosa Cell Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid hormone mediated signaling pathway GO:0043401 9.16 PGR ESR1
2 uterus development GO:0060065 8.96 FOXL2 ESR1
3 ovulation from ovarian follicle GO:0001542 8.62 PGR AFP

Molecular functions related to Adult Type Testicular Granulosa Cell Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid hormone receptor activity GO:0003707 9.26 PGR ESR1
2 nuclear receptor activity GO:0004879 9.16 PGR ESR1
3 estrogen receptor binding GO:0030331 8.96 FOXL2 ESR1
4 steroid binding GO:0005496 8.62 PGR ESR1

Sources for Adult Type Testicular Granulosa Cell Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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