MCID: ADL043
MIFTS: 20

Adult Type Testicular Granulosa Cell Tumor

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Adult Type Testicular Granulosa Cell Tumor

MalaCards integrated aliases for Adult Type Testicular Granulosa Cell Tumor:

Name: Adult Type Testicular Granulosa Cell Tumor 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:8394
NCIt 49 C39946
UMLS 71 C1515284

Summaries for Adult Type Testicular Granulosa Cell Tumor

MalaCards based summary : Adult Type Testicular Granulosa Cell Tumor is related to testicular granulosa cell tumor and gynandroblastoma. An important gene associated with Adult Type Testicular Granulosa Cell Tumor is THEM6 (Thioesterase Superfamily Member 6). Affiliated tissues include testis.

Related Diseases for Adult Type Testicular Granulosa Cell Tumor

Diseases in the Testicular Granulosa Cell Tumor family:

Juvenile Type Testicular Granulosa Cell Tumor Adult Type Testicular Granulosa Cell Tumor

Diseases related to Adult Type Testicular Granulosa Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 178)
# Related Disease Score Top Affiliating Genes
1 testicular granulosa cell tumor 30.1 FOXL2 CALB2 AFP
2 gynandroblastoma 10.3 FOXL2 CALB2
3 luteoma 10.3 FOXL2 CALB2
4 ovarian melanoma 10.2 MLANA CALB2
5 uterus perivascular epithelioid cell tumor 10.2 MLANA CALB2
6 thymus clear cell carcinoma 10.2 MLANA CALB2
7 mucinous stomach adenocarcinoma 10.2 MLANA CALB2
8 fallopian tube carcinosarcoma 10.2 NCAM1 CALB2
9 rete testis adenoma 10.2 NCAM1 CALB2
10 wolffian duct adenocarcinoma 10.2 ESR1 CALB2
11 ovarian serous adenofibroma 10.2 NCAM1 CALB2
12 ovarian serous cystadenofibroma 10.2 NCAM1 CALB2
13 glomangiosarcoma 10.1 NCAM1 MLANA
14 sensory organ benign neoplasm 10.1 NCAM1 MLANA
15 intravascular fasciitis 10.1 MLANA ESR1
16 granular cell tumor 10.1 MLANA CALB2
17 cardiovascular cancer 10.1 MLANA CALB2
18 connective tissue benign neoplasm 10.1 MLANA CALB2
19 testicular cancer 10.1
20 glomangiomatosis 10.1 NCAM1 MLANA
21 peritoneal benign neoplasm 10.1 PGR CALB2
22 olfactory nerve neoplasm 10.1 NCAM1 MLANA
23 cranial nerve malignant neoplasm 10.1 NCAM1 MLANA
24 cranial nerve neoplasm 10.1 NCAM1 MLANA
25 ovarian endometrioid stromal sarcoma 10.1 PGR CALB2
26 endosalpingiosis 10.1 PGR CALB2
27 cervical serous adenocarcinoma 10.1 PGR MLANA
28 adrenal cortical carcinoma 10.1 MLANA CALB2
29 perivascular epithelioid cell tumor 10.1 PGR MLANA
30 malignant spiradenoma 10.1 PGR CALB2
31 peritoneal serous adenocarcinoma 10.1 PGR CALB2
32 large cell neuroendocrine carcinoma 10.1 NCAM1 CALB2
33 glassy cell carcinoma of the cervix 10.0 PGR ESR1
34 bartholin's gland adenoid cystic carcinoma 10.0 PGR ESR1
35 chronic tympanitis 10.0 PGR ESR1
36 bartholin's gland adenoma 10.0 PGR ESR1
37 granulomatous endometritis 10.0 PGR ESR1
38 endometritis 10.0 PGR ESR1
39 bartholin's gland benign neoplasm 10.0 PGR ESR1
40 vestibular gland benign neoplasm 10.0 PGR ESR1
41 uterine corpus adenosarcoma 10.0 PGR ESR1
42 adenosarcoma 10.0 PGR ESR1
43 vaginal glandular tumor 10.0 PGR ESR1
44 uterus leiomyosarcoma 10.0 PGR MLANA
45 lung leiomyoma 10.0 PGR ESR1
46 vulvar syringoma 10.0 PGR ESR1
47 trigonitis 10.0 PGR ESR1
48 breast scirrhous carcinoma 10.0 PGR ESR1
49 oncocytic breast carcinoma 10.0 PGR ESR1
50 ovarian seromucinous carcinoma 10.0 PGR ESR1

Graphical network of the top 20 diseases related to Adult Type Testicular Granulosa Cell Tumor:



Diseases related to Adult Type Testicular Granulosa Cell Tumor

Symptoms & Phenotypes for Adult Type Testicular Granulosa Cell Tumor

Drugs & Therapeutics for Adult Type Testicular Granulosa Cell Tumor

Search Clinical Trials , NIH Clinical Center for Adult Type Testicular Granulosa Cell Tumor

Genetic Tests for Adult Type Testicular Granulosa Cell Tumor

Anatomical Context for Adult Type Testicular Granulosa Cell Tumor

MalaCards organs/tissues related to Adult Type Testicular Granulosa Cell Tumor:

40
Testis

Publications for Adult Type Testicular Granulosa Cell Tumor

Articles related to Adult Type Testicular Granulosa Cell Tumor:

# Title Authors PMID Year
1
Response to antiangiogenesis therapy in a patient with advanced adult-type testicular granulosa cell tumor. 61
19777766 2009
2
Adult-type testicular granulosa cell tumor: case report and review of the literature. 61
17095056 2006
3
Granulosa cell tumor of the contralateral testis in a man with a history of cryptorchism. 61
14730174 2004

Variations for Adult Type Testicular Granulosa Cell Tumor

Expression for Adult Type Testicular Granulosa Cell Tumor

Search GEO for disease gene expression data for Adult Type Testicular Granulosa Cell Tumor.

Pathways for Adult Type Testicular Granulosa Cell Tumor

GO Terms for Adult Type Testicular Granulosa Cell Tumor

Biological processes related to Adult Type Testicular Granulosa Cell Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid hormone mediated signaling pathway GO:0043401 9.16 PGR ESR1
2 uterus development GO:0060065 8.96 FOXL2 ESR1
3 ovulation from ovarian follicle GO:0001542 8.62 PGR AFP

Molecular functions related to Adult Type Testicular Granulosa Cell Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid hormone receptor activity GO:0003707 9.32 PGR ESR1
2 repressing transcription factor binding GO:0070491 9.26 PGR ESR1
3 nuclear receptor activity GO:0004879 9.16 PGR ESR1
4 estrogen receptor binding GO:0030331 8.96 FOXL2 ESR1
5 steroid binding GO:0005496 8.62 PGR ESR1

Sources for Adult Type Testicular Granulosa Cell Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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