MCID: AFB003
MIFTS: 14

Afib Amyloidosis

Categories: Bone diseases, Genetic diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Afib Amyloidosis

MalaCards integrated aliases for Afib Amyloidosis:

Name: Afib Amyloidosis 60 6
Hereditary Amyloid Nephropathy Due to Fibrinogen a Alpha-Chain Variant 60
Familial Amyloid Nephropathy Due to Fibrinogen a Alpha-Chain Variant 60
Hereditary Renal Amyloidosis Due to Fibrinogen a Alpha-Chain Variant 60
Fibrinogen a Alpha-Chain Amyloidosis 60

Characteristics:

Orphanet epidemiological data:

60
afib amyloidosis
Inheritance: Autosomal dominant;

Classifications:



External Ids:

ICD10 via Orphanet 35 E85.0
Orphanet 60 ORPHA93562

Summaries for Afib Amyloidosis

MalaCards based summary : Afib Amyloidosis, also known as hereditary amyloid nephropathy due to fibrinogen a alpha-chain variant, is related to amyloidosis, familial visceral and amyloidosis. An important gene associated with Afib Amyloidosis is FGA (Fibrinogen Alpha Chain). Affiliated tissues include kidney and bone.

Related Diseases for Afib Amyloidosis

Diseases related to Afib Amyloidosis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 amyloidosis, familial visceral 11.4
2 amyloidosis 10.3
3 chronic kidney failure 10.1
4 kidney disease 10.1

Symptoms & Phenotypes for Afib Amyloidosis

Drugs & Therapeutics for Afib Amyloidosis

Search Clinical Trials , NIH Clinical Center for Afib Amyloidosis

Genetic Tests for Afib Amyloidosis

Anatomical Context for Afib Amyloidosis

MalaCards organs/tissues related to Afib Amyloidosis:

42
Kidney, Bone

Publications for Afib Amyloidosis

Articles related to Afib Amyloidosis:

# Title Authors Year
1
Fibrinogen A alpha-chain amyloidosis: a non-negligible cause of chronic kidney disease in dialysis patients. ( 28434302 )
2017
2
Homozygosity for the E526V Mutation in Fibrinogen A Alpha-Chain Amyloidosis: The First Report. ( 26199771 )
2015
3
Fibrinogen A alpha-chain amyloidosis: report of the first case in Latin America. ( 23343498 )
2013

Variations for Afib Amyloidosis

ClinVar genetic disease variations for Afib Amyloidosis:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 FGA NM_000508.4(FGA): c.2089G> A (p.Gly697Ser) single nucleotide variant Uncertain significance rs771023837 GRCh37 Chromosome 4, 155505788: 155505788
2 FGA NM_000508.4(FGA): c.2089G> A (p.Gly697Ser) single nucleotide variant Uncertain significance rs771023837 GRCh38 Chromosome 4, 154584636: 154584636

Expression for Afib Amyloidosis

Search GEO for disease gene expression data for Afib Amyloidosis.

Pathways for Afib Amyloidosis

GO Terms for Afib Amyloidosis

Sources for Afib Amyloidosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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