MCID: AFB003
MIFTS: 17

Afib Amyloidosis

Categories: Bone diseases, Genetic diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Afib Amyloidosis

MalaCards integrated aliases for Afib Amyloidosis:

Name: Afib Amyloidosis 59 6
Hereditary Amyloid Nephropathy Due to Fibrinogen a Alpha-Chain Variant 59
Familial Amyloid Nephropathy Due to Fibrinogen a Alpha-Chain Variant 59
Hereditary Renal Amyloidosis Due to Fibrinogen a Alpha-Chain Variant 59
Fibrinogen a Alpha-Chain Amyloidosis 59

Characteristics:

Orphanet epidemiological data:

59
afib amyloidosis
Inheritance: Autosomal dominant;

Classifications:



External Ids:

ICD10 via Orphanet 34 E85.0
Orphanet 59 ORPHA93562

Summaries for Afib Amyloidosis

MalaCards based summary : Afib Amyloidosis, also known as hereditary amyloid nephropathy due to fibrinogen a alpha-chain variant, is related to amyloidosis, familial visceral and amyloidosis. An important gene associated with Afib Amyloidosis is FGA (Fibrinogen Alpha Chain). Affiliated tissues include bone, kidney and liver.

Related Diseases for Afib Amyloidosis

Diseases related to Afib Amyloidosis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 amyloidosis, familial visceral 11.5
2 amyloidosis 10.5
3 clostridium difficile colitis 10.1
4 autonomic neuropathy 10.1
5 nephrotic syndrome 10.1
6 kidney disease 10.1
7 chronic kidney disease 10.1
8 al amyloidosis 10.1

Graphical network of the top 20 diseases related to Afib Amyloidosis:



Diseases related to Afib Amyloidosis

Symptoms & Phenotypes for Afib Amyloidosis

Drugs & Therapeutics for Afib Amyloidosis

Search Clinical Trials , NIH Clinical Center for Afib Amyloidosis

Genetic Tests for Afib Amyloidosis

Anatomical Context for Afib Amyloidosis

MalaCards organs/tissues related to Afib Amyloidosis:

41
Bone, Kidney, Liver, Testes

Publications for Afib Amyloidosis

Articles related to Afib Amyloidosis:

# Title Authors PMID Year
1
Proteomic Analysis for the Diagnosis of Fibrinogen Aα-chain Amyloidosis. 38
31317119 2019
2
Pathology and diagnosis of renal non-AL amyloidosis. 38
28828707 2018
3
Unrecognized Fibrinogen A α-Chain Amyloidosis: Results From Targeted Genetic Testing. 38
28359658 2017
4
Hereditary amyloidosis caused by R554L fibrinogen Aα-chain mutation in a Spanish family and review of the literature. 38
23551149 2013
5
Fibrinogen A alpha-chain amyloidosis: report of the first case in Latin America. 38
23343498 2013
6
Prevalence and origin of amyloid in kidney biopsies. 38
19561448 2009
7
[A preemptive combined liver-kidney transplantation in Aalpha fibrinogen chain renal amyloidosis]. 38
19013120 2009
8
Three German fibrinogen Aalpha-chain amyloidosis patients with the p.Glu526Val mutation. 38
18500534 2008
9
Mutant fibrinogen A-alpha-chain associated with hereditary renal amyloidosis and peripheral neuropathy. 38
15523923 2004

Variations for Afib Amyloidosis

ClinVar genetic disease variations for Afib Amyloidosis:

6
# Gene Variation Type Significance SNP ID GRCh37 Pos GRCh38 Pos
1 FGA NM_000508.5(FGA): c.2089G> A (p.Gly697Ser) single nucleotide variant Uncertain significance rs771023837 4:155505788-155505788 4:154584636-154584636

Expression for Afib Amyloidosis

Search GEO for disease gene expression data for Afib Amyloidosis.

Pathways for Afib Amyloidosis

GO Terms for Afib Amyloidosis

Sources for Afib Amyloidosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....