MCID: AFB003
MIFTS: 14

Afib Amyloidosis

Categories: Bone diseases, Genetic diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Afib Amyloidosis

MalaCards integrated aliases for Afib Amyloidosis:

Name: Afib Amyloidosis 59 6
Hereditary Amyloid Nephropathy Due to Fibrinogen a Alpha-Chain Variant 59
Familial Amyloid Nephropathy Due to Fibrinogen a Alpha-Chain Variant 59
Hereditary Renal Amyloidosis Due to Fibrinogen a Alpha-Chain Variant 59
Fibrinogen a Alpha-Chain Amyloidosis 59

Characteristics:

Orphanet epidemiological data:

59
afib amyloidosis
Inheritance: Autosomal dominant;

Classifications:



External Ids:

Orphanet 59 ORPHA93562
ICD10 via Orphanet 34 E85.0

Summaries for Afib Amyloidosis

MalaCards based summary : Afib Amyloidosis, also known as hereditary amyloid nephropathy due to fibrinogen a alpha-chain variant, is related to amyloidosis and chronic kidney failure. An important gene associated with Afib Amyloidosis is FGA (Fibrinogen Alpha Chain). Affiliated tissues include bone and kidney.

Related Diseases for Afib Amyloidosis

Diseases related to Afib Amyloidosis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 amyloidosis 10.2
2 chronic kidney failure 10.1
3 kidney disease 10.1

Symptoms & Phenotypes for Afib Amyloidosis

Drugs & Therapeutics for Afib Amyloidosis

Search Clinical Trials , NIH Clinical Center for Afib Amyloidosis

Genetic Tests for Afib Amyloidosis

Anatomical Context for Afib Amyloidosis

MalaCards organs/tissues related to Afib Amyloidosis:

41
Bone, Kidney

Publications for Afib Amyloidosis

Articles related to Afib Amyloidosis:

# Title Authors Year
1
Fibrinogen A alpha-chain amyloidosis: a non-negligible cause of chronic kidney disease in dialysis patients. ( 28434302 )
2017
2
Fibrinogen A alpha-chain amyloidosis: report of the first case in Latin America. ( 23343498 )
2013

Variations for Afib Amyloidosis

ClinVar genetic disease variations for Afib Amyloidosis:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 FGA NM_000508.4(FGA): c.2089G> A (p.Gly697Ser) single nucleotide variant Uncertain significance rs771023837 GRCh37 Chromosome 4, 155505788: 155505788
2 FGA NM_000508.4(FGA): c.2089G> A (p.Gly697Ser) single nucleotide variant Uncertain significance rs771023837 GRCh38 Chromosome 4, 154584636: 154584636

Expression for Afib Amyloidosis

Search GEO for disease gene expression data for Afib Amyloidosis.

Pathways for Afib Amyloidosis

GO Terms for Afib Amyloidosis

Sources for Afib Amyloidosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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