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MCID: AFR001
MIFTS: 22

African Histoplasmosis

Categories: Bone diseases, Infectious diseases
Genes Tissues Related diseases Publications
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Aliases & Classifications for African Histoplasmosis

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MalaCards integrated aliases for African Histoplasmosis:

Name: African Histoplasmosis 12 15 71

Classifications:

MalaCards categories:
Global: Infectious diseases
Anatomical: Bone diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:11315
ICD9CM 34 115.10
UMLS 71 C0153270 C0220977
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Summaries for African Histoplasmosis

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Disease Ontology : 12 A histoplasmosis that results in systemic fungal infection, has material basis in Histoplasma capsulatum var duboisii, transmitted by airborne spores and results in formation of nodules, results in formation of ulcers and results in formation of osteolytic bone lesions.

MalaCards based summary : African Histoplasmosis is related to histoplasmosis and fungal infectious disease. An important gene associated with African Histoplasmosis is FAM126A (Family With Sequence Similarity 126 Member A). Affiliated tissues include bone, skin and lymph node.

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Related Diseases for African Histoplasmosis

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Diseases related to African Histoplasmosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
# Related Disease Score Top Affiliating Genes
1 histoplasmosis 31.4 FAM126A CD4
2 fungal infectious disease 30.1 RHNO1 CD4
3 human immunodeficiency virus type 1 10.1
4 osteomyelitis 10.1
5 acute orbital inflammation 10.0 RHNO1 CD4
6 cerebritis 10.0 RHNO1 CD4
7 cranial nerve palsy 10.0 RHNO1 CD4
8 mucormycosis 10.0 RHNO1 CD4
9 conjunctival disease 10.0 RHNO1 CD4
10 paranasal sinus disease 10.0 RHNO1 CD4
11 burkitt lymphoma 10.0
12 paracoccidioidomycosis 10.0
13 blastomycosis 10.0
14 sporotrichosis 10.0
15 american histoplasmosis 10.0
16 acquired immunodeficiency syndrome 10.0
17 opportunistic mycosis 10.0 RHNO1 CD4
18 nose disease 9.9 RHNO1 CD4
19 borst-jadassohn intraepidermal carcinoma 9.9 KRT10 CD4
20 osteogenic sarcoma 9.8
21 kala-azar 1 9.8
22 lymphoma 9.8
23 gastric ulcer 9.8
24 cryptococcosis 9.8
25 inflammatory spondylopathy 9.8
26 diarrhea 9.8
27 coccidioidomycosis 9.8
28 chromoblastomycosis 9.8
29 gingivitis 9.8
30 chronic granulomatous disease 9.8
31 tinea capitis 9.8
32 paraplegia 9.8
33 spondylitis 9.8
34 molluscum contagiosum 9.8
35 dermatophytosis 9.8
36 leishmaniasis 9.8
37 visceral leishmaniasis 9.8
38 sickle cell disease 9.8
39 mycetoma 9.8
40 chediak-higashi syndrome 9.8 CD4 AP3B1
41 integumentary system disease 9.7 KRT10 CD4
42 papilloma 9.6 KRT10 CD4
43 autoimmune lymphoproliferative syndrome 9.5 PAM16 CD4

Graphical network of the top 20 diseases related to African Histoplasmosis:



Diseases related to African Histoplasmosis
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Symptoms & Phenotypes for African Histoplasmosis

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Drugs & Therapeutics for African Histoplasmosis

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Search Clinical Trials , NIH Clinical Center for African Histoplasmosis

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Genetic Tests for African Histoplasmosis

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Anatomical Context for African Histoplasmosis

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MalaCards organs/tissues related to African Histoplasmosis:

40
Bone, Skin, Lymph Node, Colon, Lung
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Publications for African Histoplasmosis

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Articles related to African Histoplasmosis:

(show top 50) (show all 148)
# Title Authors PMID Year
1
African histoplasmosis in a Guinea Bissau patient with HIV-2: Case report and review. 61
31706701 2020
2
Gingival histoplasmosis: An atypical presentation of African histoplasmosis in three baboons (Papio spp). 61
31595520 2020
3
Modification of the Francis Medium for the Conversion of Histoplasma capsulatum to the Yeast-Like Growth Phase. 61
31177444 2019
4
African Histoplasmosis in HIV-Negative Patients, Kimpese, Democratic Republic of the Congo. 61
30334708 2018
5
Non-tubercular caseous adenopathy in Senegal. 61
30270827 2018
6
African histoplasmosis: new clinical and microbiological insights. 61
28431110 2018
7
Tonsillar ulceration as manifestation of disseminated African histoplasmosis in an immunocompetent Portuguese host. 61
28626627 2017
8
Histoplasmosis by Histoplasma capsulatum var. duboisii Observed at the Laboratory of Pathological Anatomy of Lomé in Togo. 61
28804654 2017
9
[Multifocal histoplasmosis due to Histoplasma capsulatum var. duboisii in a 22 year-old Senegalese patient without proven immunodepression]. 61
27158080 2016
10
[Nondermatophytic and noncandidal fungi isolated in Le Dantec University hospital of Dakar in 2014: Epidemiological, clinical and mycological study]. 61
26138533 2015
11
Disseminated histoplasmosis caused by Histoplasma capsulatum var. duboisii in a non-HIV patient in Burkina Faso: Case report. 61
25840849 2015
12
African histoplasmosis: the first report of an indigenous case in India. 61
25514986 2015
13
Disseminated Histoplasmosis and Secondary Hemophagocytic Syndrome in a Non-HIV Patient. 61
26347828 2015
14
Imported African histoplasmosis in an immunocompetent patient 40 years after staying in a disease-endemic area. 61
25246691 2014
15
[Malian first observation of disseminated African histoplasmosis with predominant bone localizations in an HIV-negative child in Bamako (Mali). Review of the literature]. 61
24094479 2014
16
[Aspergillus galactomannan assay for the management of histoplasmosis due to Histoplasma capsulatum var. duboisii in HIV-infected patients: education from a clinical case]. 61
24636196 2014
17
Posaconazole as rescue therapy in African histoplasmosis. 61
23312726 2013
18
An unusual cutaneous tumor: African histoplasmosis following mudbaths: case report and review. 61
22302860 2012
19
A case of disseminated histoplasmosis detected in peripheral blood smear staining revealing AIDS at terminal phase in a female patient from cameroon. 61
23251167 2012
20
[Disseminated histoplasmosis due to Histoplasma capsulatum var. duboisii in Senegal. A case in HIV-infected patient]. 61
24451506 2011
21
[African histoplasmosis in an immunocompetent Malagasy patient.]. 61
20099053 2010
22
Literature review and case histories of Histoplasma capsulatum var. duboisii infections in HIV-infected patients. 61
18217546 2007
23
[Pathological fracture revealing an osseous histoplasmosis. A case report on a 60-year patient]. 61
17111967 2006
24
African histoplasmosis - masquerading as a malignant bone tumour. 61
17034712 2006
25
[African histoplasmosis (Histoplasma capsulatum var. duboisii): a case report from Mali]. 61
16207583 2005
26
Maxillary African histoplasmosis: unusual diagnostic problems of an unusual presentation. 61
15792130 2005
27
African histoplasmosis infection with peritoneal involvement. 61
15015032 2004
28
[Cervico-facial and ENT symptoms due to HIV infection in tropical area. About 253 Congolese cases]. 61
15104161 2004
29
Histoplasma capsulatum var. capsulatum occurring in an HIV-positive Ghanaian immigrant to Italy. Identification of H. capsulatum DNA by PCR from paraffin sample. 61
11900050 2001
30
[Spondylodiscitis due to Histoplasma duboisii. Report of two cases and review of the literature]. 61
11493872 2001
31
Spinal African histoplasmosis simulating tuberculous spondylitis. 61
12789131 2001
32
Histoplasmosis in Africa: a review. 61
15597674 2000
33
Zoonotic infections in Nigeria: overview from a medical perspective. 61
10913768 2000
34
Antibodies to antigens of Histoplasma, Blastomyces and Candida in HIV patients and carriers in Nigeria. 61
10948814 2000
35
Some deep mycoses diagnosed by histopathology in South Eastern Nigeria. 61
18473552 1999
36
African oral histoplasmosis mimicking lip carcinoma: case report. 61
10520359 1999
37
Fluconazole in the therapy of multiple osteomyelitis in African histoplasmosis. 61
10422020 1999
38
African histoplasmosis: report of two patients treated with amphotericin B and ketoconazole. 61
9916457 1998
39
African histoplasmosis: report of four cases from north-eastern Nigeria. 61
9861834 1998
40
African histoplasmosis: osteomyelitis of the radius. 61
9670760 1998
41
African histoplasmosis: therapeutic efficacy of itraconazole. 61
9552764 1998
42
African histoplasmosis: a review. 61
15538817 1997
43
[African histoplasmosis with ganglionic localisation. Apropos of 1 case in an HIV negative patient]. 61
9410255 1997
44
Focal lesion of African histoplasmosis presenting as a malignant gastric ulcer. 61
8799429 1996
45
[African histoplasmosis in a patient with HIV-2 infection]. 61
8693301 1996
46
Extracellular proteolytic enzyme activity of Histoplasma capsulatum var. duboisii. 61
8817930 1996
47
Skin and serum reactivity among humans to histoplasmin in the vicinity of a natural focus of Histoplasma capsulatum var. duboisii. 61
9011827 1996
48
Fluconazole in the therapy of tropical deep mycoses. 61
8720201 1995
49
[Generalized molluscum contagiosum in an African child with AIDS]. 61
8641888 1995
50
[African histoplasmosis due to Histoplasma capsulatum var. duboisii: relationship with AIDS in recent Congolese cases]. 61
7582643 1995
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Variations for African Histoplasmosis

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Expression for African Histoplasmosis

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Search GEO for disease gene expression data for African Histoplasmosis.
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Pathways for African Histoplasmosis

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GO Terms for African Histoplasmosis

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Cellular components related to African Histoplasmosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 clathrin-coated vesicle membrane GO:0030665 8.62 CD4 AP3B1

Biological processes related to African Histoplasmosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane organization GO:0061024 8.62 CD4 AP3B1
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Sources for African Histoplasmosis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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