MCID: AFR001
MIFTS: 24

African Histoplasmosis

Categories: Bone diseases, Infectious diseases

Aliases & Classifications for African Histoplasmosis

MalaCards integrated aliases for African Histoplasmosis:

Name: African Histoplasmosis 12 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:11315
ICD9CM 35 115.10
UMLS 72 C0153270 C0220977

Summaries for African Histoplasmosis

Disease Ontology : 12 A histoplasmosis that results in systemic fungal infection, has material basis in Histoplasma capsulatum var duboisii, transmitted by airborne spores and results in formation of nodules, results in formation of ulcers and results in formation of osteolytic bone lesions.

MalaCards based summary : African Histoplasmosis is related to histoplasmosis and osteomyelitis. An important gene associated with African Histoplasmosis is RHNO1 (RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1), and among its related pathways/superpathways are Circadian entrainment and Regulation of TP53 Activity. Affiliated tissues include bone, skin and colon.

Related Diseases for African Histoplasmosis

Diseases related to African Histoplasmosis via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 26, show less)
# Related Disease Score Top Affiliating Genes
1 histoplasmosis 10.8
2 osteomyelitis 10.1
3 burkitt lymphoma 10.0
4 human immunodeficiency virus type 1 10.0
5 paracoccidioidomycosis 10.0
6 blastomycosis 10.0
7 sporotrichosis 10.0
8 acquired immunodeficiency syndrome 10.0
9 osteogenic sarcoma 9.8
10 kala-azar 1 9.8
11 lymphoma 9.8
12 gastric ulcer 9.8
13 cryptococcosis 9.8
14 inflammatory spondylopathy 9.8
15 coccidioidomycosis 9.8
16 chromoblastomycosis 9.8
17 american histoplasmosis 9.8
18 chronic granulomatous disease 9.8
19 tinea capitis 9.8
20 paraplegia 9.8
21 spondylitis 9.8
22 dermatophytosis 9.8
23 leishmaniasis 9.8
24 visceral leishmaniasis 9.8
25 sickle cell disease 9.8
26 mycetoma 9.8

Graphical network of the top 20 diseases related to African Histoplasmosis:



Diseases related to African Histoplasmosis

Symptoms & Phenotypes for African Histoplasmosis

Drugs & Therapeutics for African Histoplasmosis

Search Clinical Trials , NIH Clinical Center for African Histoplasmosis

Genetic Tests for African Histoplasmosis

Anatomical Context for African Histoplasmosis

MalaCards organs/tissues related to African Histoplasmosis:

41
Bone, Skin, Colon, Lung, Lymph Node

Publications for African Histoplasmosis

Articles related to African Histoplasmosis:

(showing 146, show less)
# Title Authors PMID Year
1
Modification of the Francis Medium for the Conversion of Histoplasma capsulatum to the Yeast-Like Growth Phase. 38
31177444 2019
2
African Histoplasmosis in HIV-Negative Patients, Kimpese, Democratic Republic of the Congo. 38
30334708 2018
3
Non-tubercular caseous adenopathy in Senegal. 38
30270827 2018
4
African histoplasmosis: new clinical and microbiological insights. 38
28431110 2018
5
Tonsillar ulceration as manifestation of disseminated African histoplasmosis in an immunocompetent Portuguese host. 38
28626627 2017
6
Histoplasmosis by Histoplasma capsulatum var. duboisii Observed at the Laboratory of Pathological Anatomy of Lomé in Togo. 38
28804654 2017
7
[Multifocal histoplasmosis due to Histoplasma capsulatum var. duboisii in a 22 year-old Senegalese patient without proven immunodepression]. 38
27158080 2016
8
[Nondermatophytic and noncandidal fungi isolated in Le Dantec University hospital of Dakar in 2014: Epidemiological, clinical and mycological study]. 38
26138533 2015
9
Disseminated histoplasmosis caused by Histoplasma capsulatum var. duboisii in a non-HIV patient in Burkina Faso: Case report. 38
25840849 2015
10
African histoplasmosis: the first report of an indigenous case in India. 38
25514986 2015
11
Disseminated Histoplasmosis and Secondary Hemophagocytic Syndrome in a Non-HIV Patient. 38
26347828 2015
12
Imported African histoplasmosis in an immunocompetent patient 40 years after staying in a disease-endemic area. 38
25246691 2014
13
[Aspergillus galactomannan assay for the management of histoplasmosis due to Histoplasma capsulatum var. duboisii in HIV-infected patients: education from a clinical case]. 38
24636196 2014
14
[Malian first observation of disseminated African histoplasmosis with predominant bone localizations in an HIV-negative child in Bamako (Mali). Review of the literature]. 38
24094479 2014
15
Posaconazole as rescue therapy in African histoplasmosis. 38
23312726 2013
16
An unusual cutaneous tumor: African histoplasmosis following mudbaths: case report and review. 38
22302860 2012
17
A case of disseminated histoplasmosis detected in peripheral blood smear staining revealing AIDS at terminal phase in a female patient from cameroon. 38
23251167 2012
18
[Disseminated histoplasmosis due to Histoplasma capsulatum var. duboisii in Senegal. A case in HIV-infected patient]. 38
24451506 2011
19
[African histoplasmosis in an immunocompetent Malagasy patient.]. 38
20099053 2010
20
Literature review and case histories of Histoplasma capsulatum var. duboisii infections in HIV-infected patients. 38
18217546 2007
21
[Pathological fracture revealing an osseous histoplasmosis. A case report on a 60-year patient]. 38
17111967 2006
22
African histoplasmosis - masquerading as a malignant bone tumour. 38
17034712 2006
23
[African histoplasmosis (Histoplasma capsulatum var. duboisii): a case report from Mali]. 38
16207583 2005
24
Maxillary African histoplasmosis: unusual diagnostic problems of an unusual presentation. 38
15792130 2005
25
African histoplasmosis infection with peritoneal involvement. 38
15015032 2004
26
[Cervico-facial and ENT symptoms due to HIV infection in tropical area. About 253 Congolese cases]. 38
15104161 2004
27
Histoplasma capsulatum var. capsulatum occurring in an HIV-positive Ghanaian immigrant to Italy. Identification of H. capsulatum DNA by PCR from paraffin sample. 38
11900050 2001
28
[Spondylodiscitis due to Histoplasma duboisii. Report of two cases and review of the literature]. 38
11493872 2001
29
Spinal African histoplasmosis simulating tuberculous spondylitis. 38
12789131 2001
30
Histoplasmosis in Africa: a review. 38
15597674 2000
31
Zoonotic infections in Nigeria: overview from a medical perspective. 38
10913768 2000
32
Antibodies to antigens of Histoplasma, Blastomyces and Candida in HIV patients and carriers in Nigeria. 38
10948814 2000
33
Some deep mycoses diagnosed by histopathology in South Eastern Nigeria. 38
18473552 1999
34
African oral histoplasmosis mimicking lip carcinoma: case report. 38
10520359 1999
35
Fluconazole in the therapy of multiple osteomyelitis in African histoplasmosis. 38
10422020 1999
36
African histoplasmosis: report of two patients treated with amphotericin B and ketoconazole. 38
9916457 1998
37
African histoplasmosis: report of four cases from north-eastern Nigeria. 38
9861834 1998
38
African histoplasmosis: osteomyelitis of the radius. 38
9670760 1998
39
African histoplasmosis: therapeutic efficacy of itraconazole. 38
9552764 1998
40
African histoplasmosis: a review. 38
15538817 1997
41
[African histoplasmosis with ganglionic localisation. Apropos of 1 case in an HIV negative patient]. 38
9410255 1997
42
Focal lesion of African histoplasmosis presenting as a malignant gastric ulcer. 38
8799429 1996
43
[African histoplasmosis in a patient with HIV-2 infection]. 38
8693301 1996
44
Skin and serum reactivity among humans to histoplasmin in the vicinity of a natural focus of Histoplasma capsulatum var. duboisii. 38
9011827 1996
45
Extracellular proteolytic enzyme activity of Histoplasma capsulatum var. duboisii. 38
8817930 1996
46
Fluconazole in the therapy of tropical deep mycoses. 38
8720201 1995
47
[Generalized molluscum contagiosum in an African child with AIDS]. 38
8641888 1995
48
[African histoplasmosis due to Histoplasma capsulatum var. duboisii: relationship with AIDS in recent Congolese cases]. 38
7582643 1995
49
[Multiple bone lesions of a type of disseminated African histoplasmosis in a Togolese immunocompetent child]. 38
8761658 1995
50
[Bone and joint sites of African histoplasmosis (Histoplasma duboisii). Apropos of a case and review of the literature]. 38
7858578 1994
51
Deep fungal infections in the tropics. 38
7805298 1994
52
A natural focus of Histoplasma capsulatum var. duboisii is a bat cave. 38
7808510 1994
53
[African histoplasmosis: clinical and therapeutic aspects, relation to AIDS. Apropos of 4 cases, including a case with HIV-1-HTLV-1 co-infection]. 38
7864504 1994
54
African histoplasmosis. Report of the first case in Brazil and treatment with itraconazole. 38
8278762 1993
55
African histoplasmosis (Duboisii) of the skull with neurological complication--a case report and review of literature. 38
1308076 1992
56
Disseminated African histoplasmosis in a Congolese patient with AIDS. 38
1517960 1992
57
Tropical mycoses. 38
1319312 1992
58
[Tropical mycoses]. 38
1663201 1991
59
An epizootic of histoplasmosis duboisii (African histoplasmosis) in an American baboon colony. 38
1666137 1991
60
[African histoplasmosis of the colon]. 38
1783257 1991
61
African histoplasmosis in a Belgian AIDS patient. 38
1922190 1991
62
Histoplasmosis duboisii (African histoplasmosis). An African case reported from Chile with ultrastructural study. 38
2247379 1990
63
Is African histoplasmosis an opportunistic fungal infection in AIDS? 38
2389325 1990
64
Further studies on the treatment of African histoplasmosis with ketoconazole. 38
2617613 1989
65
African histoplasmosis masquerading as carcinoma of the colon. Report of a case and review of literature. 38
2676427 1989
66
[Histologic diagnosis of African histoplasmosis (the first case of the disease in the USSR)]. 38
2712731 1989
67
[African histoplasmosis]. 38
2727770 1989
68
Enlarged cervical lymph node due to African histoplasmosis. 38
3199018 1988
69
Case of disseminated African histoplasmosis in a baboon. 38
3184166 1988
70
A case of African histoplasmosis from Sudan. 38
3232196 1988
71
Mandibular African histoplasmosis: imitation of neoplasia or giant-cell granuloma? 38
3422400 1988
72
Disseminated African histoplasmosis in a white heterosexual male patient with the acquired immune deficiency syndrome. 38
3437911 1987
73
African histoplasmosis in Ethiopia: a case report. 38
3691358 1987
74
[African histoplasmosis in Mali]. 38
3631825 1987
75
Orbital histoplasmosis due to Histoplasma capsulatum var. duboisii: successful treatment with Septrin. 38
3491220 1986
76
[Histoplasmosis]. 38
3773679 1986
77
[A new case of African histoplasmosis with multiple localizations in the bones]. 38
3773689 1986
78
[Disseminated Histoplasma duboisii histoplasmosis in a female inhabitant of the Ivory Coast]. 38
6097790 1984
79
What's new in mycotic bone and joint diseases? 38
6483686 1984
80
[African histoplasmosis. A case]. 38
6487046 1984
81
Treatment of African histoplasmosis with ketoconazole. 38
6306875 1983
82
Chronic Progressive Disseminated Mucocutaneous Histoplasmosis. 38
28176687 1983
83
African histoplasmosis manifesting as a cutaneous tumour treated with econazole. 38
7154150 1982
84
[African histoplasmosis; immunological parameters and treatment with ketoconazole]. 38
6294513 1982
85
African histoplasmosis presenting as a facial tumour in a child. 38
6191632 1982
86
African histoplasmosis in Connecticut. 38
7105705 1982
87
[Thoracic bone lesions in African histoplasmosis]. 38
6750717 1982
88
African histoplasmosis in the United States. 38
7463662 1981
89
[Fungal osteoarthritis]. 38
7221443 1981
90
[African histoplasmosis of the lung (author's transl)]. 38
7371514 1980
91
[African histoplasmosis]. 38
7390808 1980
92
[African histoplasmosis in an Angolan woman: clinical aspects, histology and mycology]. 38
527741 1979
93
[African histoplasmosis (author's transl)]. 38
470975 1979
94
Maxillary African histoplasmosis mimicking malignant jaw tumour. 38
285725 1979
95
African histoplasmosis in Eastern Nigeria: report of two culturally proven cases treated with septrin and amphotericin B. 38
731765 1978
96
Oral African histoplasmosis resembling Burkitt's lymphoma. 38
278937 1978
97
African histoplasmosis of the jejunum. Report of a case. 38
660708 1978
98
[A case of African histoplasmosis (Histoplasma Duboisii)]. 38
635402 1978
99
[Systemic mycoses. 2. Systemic mycoses caused by dimorphous fungi (African histoplasmosis, blastomycosis, paracoccidioidomycosis,, sporotrichosis)]. 38
976915 1976
100
[Systemic mycoses. 1. Systemic mycoses due to dimorphous fungi (coccidioidomycosis, histoplasmosis, African histoplasmosis, blastomycosis, paracoccidioidomycosis, sporotrichosis)]. 38
964880 1976
101
[Clinical, mycological, and histopathological study of African histoplasmosis]. 38
1252964 1976
102
Perfect state (Emmonsiella capsulata) of the fungus causing large-form African histoplasmosis. 38
1196334 1975
103
[A rare case of granulomatous enteritis: African histoplasmosis?]. 38
4417841 1974
104
[2 new cases of African histoplasmosis]. 38
4791927 1973
105
[Imported pathology: African histoplasmosis due to Histoplasma duboisii]. 38
4266494 1972
106
[African histoplasmosis caused by an insect bite]. 38
4553713 1972
107
[African histoplasmosis in a pseudotuberculous ganglionic form]. 38
4663852 1972
108
Epidemiology of African histoplasmosis. 38
4627123 1972
109
[Clinical aspects of African histoplasmosis]. 38
5070637 1972
110
African histoplasmosis due to Histoplasma duboisii. 38
5165016 1971
111
Cutaneous manifestations of African histoplasmosis. 38
5092425 1971
112
African histoplasmosis complicating pregnancy. 38
5159139 1971
113
[2 cases of African histoplasmosis treated with success with amphotericin B]. 38
4934975 1971
114
[African histoplasmosis of cutaneous, osseous, lymph node and pulmonary form (apropos of a case)]. 38
5161182 1971
115
Pathology of African histoplasmosis (H. duboisii)--light and electron microscopy. 38
4926980 1970
116
African histoplasmosis presenting as a dental problem. 38
5272571 1970
117
[Neurologic and pulmonary forms of African histoplasmosis]. 38
5516713 1970
118
Cutaneous manifestations of African histoplasmosis. 38
5431549 1970
119
[Unusual differential diagnosis of suboccipital Pott's disease: sternal and occipito-atloid African histoplasmosis]. 38
5402867 1969
120
[Value and limitations of lymphography in mycoses. (Apropos of 2 cases of mycetoma and 1 case of African histoplasmosis)]. 38
5395494 1969
121
[2 cases of African histoplasmosis in Upper Volta]. 38
5692838 1968
122
Pulmonary lesions in African histoplasmosis. 38
5638339 1968
123
[Radiological aspect of African histoplasmosis]. 38
5759962 1968
124
[African histoplasmosis and chromoblastomycosis in Angolians]. 38
5619092 1967
125
[New cases of African histoplasmosis and cryptococcosis observed in the Republic of the Congo]. 38
5607675 1967
126
[African histoplasmosis of the large form]. 38
5988591 1966
127
[Cutaneous manifestations of African histoplasmosis]. 38
4864945 1966
128
[3 new cases of African histoplasmosis]. 38
5973725 1966
129
[Extensive type of African histoplasmosis]. 38
5877032 1965
130
[Clinical study of African histoplasmosis]. 38
5838212 1965
131
[SKIN MANIFESTATIONS OF AFRICAN HISTOPLASMOSIS]. 38
14323524 1964
132
[AFRICAN HISTOPLASMOSIS OR HISTOPLASMOSIS CAUSED BY HISTOPLASMA DUBOISII VANBREUSEGHEM 1952]. 38
14206275 1964
133
[THE FIRST ANGOLESE CASE OF AFRICAN HISTOPLASMOSIS]. 38
14115001 1963
134
[Cutaneous forms of African histoplasmosis]. 38
13969883 1963
135
[A case of osteocutaneous African histoplasmosis]. 38
14493001 1962
136
[A recent case of African histoplasmosis observed in the Congo]. 38
14039951 1962
137
[African histoplasmosis with capsulatum forms caused by Histoplasma duboisii Vanbreuseghem 1952]. 38
13885899 1961
138
[African histoplasmosis (Histoplasma duboisii, Vanbreuseghem 1952) of the skin]. 38
13789416 1961
139
[African histoplasmosis in extensive form with multiple bone localizations. Favorable outcome following surgical intervention and amphotericin B]. 38
13793504 1959
140
[African histoplasmosis of the lungs with diffuse suppuration appearing after a year's development]. 38
13654699 1959
141
Tropical African histoplasmosis. 38
13592890 1958
142
[Action of amphotericin B in serious forms of African histoplasmosis]. 38
13536778 1958
143
[Attempt of a restatement on African histoplasmosis]. 38
13608145 1958
144
Tinea capitis and African histoplasmosis in the Belgian Congo. 38
13443007 1957
145
African histoplasmosis. 38
13118626 1953
146
[A case of African histoplasmosis; with a mycological note on Histoplasma duboisii n.sp]. 38
13040947 1952

Variations for African Histoplasmosis

Expression for African Histoplasmosis

Search GEO for disease gene expression data for African Histoplasmosis.

Pathways for African Histoplasmosis

GO Terms for African Histoplasmosis

Biological processes related to African Histoplasmosis according to GeneCards Suite gene sharing:

(showing 3, show less)
# Name GO ID Score Top Affiliating Genes
1 cellular response to DNA damage stimulus GO:0006974 9.16 RHNO1 MAPK14
2 cellular response to ionizing radiation GO:0071479 8.96 RHNO1 MAPK14
3 DNA damage checkpoint GO:0000077 8.62 RHNO1 MAPK14

Sources for African Histoplasmosis

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