MCID: AGR014
MIFTS: 9

Age-Related Hearing Impairment 2

Aliases & Classifications for Age-Related Hearing Impairment 2

MalaCards integrated aliases for Age-Related Hearing Impairment 2:

Name: Age-Related Hearing Impairment 2 57 13
Presbycusis 2 57 73
Arhi2 57

External Ids:

OMIM 57 612976
MedGen 42 C2751814
UMLS 73 C2751814

Summaries for Age-Related Hearing Impairment 2

OMIM : 57 Age-related hearing impairment (ARHI), or presbycusis, is the progressive, bilaterally symmetric deterioration of hearing ability that occurs with aging. Studies of the cochlea in many animal species and of the histopathology of human temporal bones have shown that stria vascularis volumes and spiral ganglion cell, inner hair cell, and outer hair cell populations, as well as many other cochlear cell types and structures, undergo age-related degeneration. Environmental risk factors for ARHI include noise exposure, smoking, ototoxic medication, and cardiovascular disease. Heritability estimates vary between 0.25 and 0.75 depending on, among other factors, study design (family vs twins), age range of the study population, and the phenotype studied (Huyghe et al., 2008). (612976)

MalaCards based summary : Age-Related Hearing Impairment 2, also known as presbycusis 2, is related to age-related hearing loss. An important gene associated with Age-Related Hearing Impairment 2 is ARHI2 (Age-Related Hearing Impairment 2). Affiliated tissues include bone.

Related Diseases for Age-Related Hearing Impairment 2

Diseases in the Age-Related Hearing Impairment 1 family:

Age-Related Hearing Impairment 2

Diseases related to Age-Related Hearing Impairment 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 age-related hearing loss 10.9

Symptoms & Phenotypes for Age-Related Hearing Impairment 2

Clinical features from OMIM:

612976

Drugs & Therapeutics for Age-Related Hearing Impairment 2

Search Clinical Trials , NIH Clinical Center for Age-Related Hearing Impairment 2

Genetic Tests for Age-Related Hearing Impairment 2

Anatomical Context for Age-Related Hearing Impairment 2

MalaCards organs/tissues related to Age-Related Hearing Impairment 2:

41
Bone

Publications for Age-Related Hearing Impairment 2

Variations for Age-Related Hearing Impairment 2

Expression for Age-Related Hearing Impairment 2

Search GEO for disease gene expression data for Age-Related Hearing Impairment 2.

Pathways for Age-Related Hearing Impairment 2

GO Terms for Age-Related Hearing Impairment 2

Sources for Age-Related Hearing Impairment 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....