MCID: AGG003
MIFTS: 33

Aggressive Digital Papillary Adenocarcinoma

Categories: Cancer diseases

Aliases & Classifications for Aggressive Digital Papillary Adenocarcinoma

MalaCards integrated aliases for Aggressive Digital Papillary Adenocarcinoma:

Name: Aggressive Digital Papillary Adenocarcinoma 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:5590

Summaries for Aggressive Digital Papillary Adenocarcinoma

MalaCards based summary : Aggressive Digital Papillary Adenocarcinoma is related to paronychia and adenocarcinoma. An important gene associated with Aggressive Digital Papillary Adenocarcinoma is MUC1 (Mucin 1, Cell Surface Associated), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Endometrial cancer. Affiliated tissues include lymph node, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 76 Aggressive digital papillary adenocarcinoma (also known as a digital papillary adenocarcinoma and... more...

Related Diseases for Aggressive Digital Papillary Adenocarcinoma

Diseases related to Aggressive Digital Papillary Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 156)
# Related Disease Score Top Affiliating Genes
1 paronychia 30.6 HRAS KRAS
2 adenocarcinoma 30.1 HRAS KIT KRAS MUC1 PIK3CA
3 squamous cell carcinoma 29.5 HRAS KRAS MUC1 PIK3CA
4 localized hypertrophic neuropathy 10.9 MUC1 S100B
5 sclerosing perineurioma 10.9 MUC1 S100B
6 intracranial cysts 10.8 MUC1 S100B
7 non-functioning pituitary adenoma 10.8 MUC1 S100B
8 epithelioid malignant peripheral nerve sheath tumor 10.8 MUC1 S100B
9 sinonasal undifferentiated carcinoma 10.8 CEACAM3 MUC1
10 ossifying fibromyxoid tumor 10.8 MUC1 S100B
11 fibrous meningioma 10.8 MUC1 S100B
12 chordoid meningioma 10.8 MUC1 S100B
13 eccrine porocarcinoma 10.8 MUC1 S100B
14 spindle cell rhabdomyosarcoma 10.8 MUC1 S100B
15 myxopapillary ependymoma 10.8 MUC1 S100B
16 monophasic synovial sarcoma 10.8 MUC1 S100B
17 chordoid glioma 10.8 MUC1 S100B
18 spiradenoma 10.8 MUC1 S100B
19 syringoma 10.7 MUC1 S100B
20 pleomorphic liposarcoma 10.7 MUC1 S100B
21 malignant mixed mullerian tumor 10.7 KIT MUC1
22 papillary adenocarcinoma 10.7
23 eccrine papillary adenocarcinoma 10.7
24 rosette-forming glioneuronal tumor 10.7 PIK3CA S100B
25 anaplastic ependymoma 10.7 MUC1 S100B
26 sarcomatoid renal cell carcinoma 10.7 KIT MUC1
27 hidradenoma 10.7 MUC1 PIK3CA
28 rare adenocarcinoma of the breast 10.6 KRAS PIK3CA
29 perivascular epithelioid cell tumor 10.6 KIT MUC1
30 spindle cell sarcoma 10.6 MUC1 S100B
31 functioning pituitary adenoma 10.6 MUC1 S100B
32 amelanotic melanoma 10.6 KIT S100B
33 papilloma of choroid plexus 10.6 MUC1 S100B
34 prostate adenoid cystic carcinoma 10.6 HRAS PIK3CA
35 thymoma, familial 10.6 HRAS KIT
36 villous adenoma 10.6 KRAS MUC1
37 appendix cancer 10.6 KRAS MUC1
38 meningeal melanocytoma 10.5 MUC1 S100B
39 dermoid cyst 10.5 KIT MUC1
40 papillary hidradenoma 10.5 KIT PIK3CA
41 ethmoid sinus cancer 10.5 HRAS PIK3CA
42 ethmoid sinus adenocarcinoma 10.5 HRAS PIK3CA
43 ovarian melanoma 10.5 HRAS KIT
44 rosai-dorfman disease 10.5 KRAS S100B
45 schimmelpenning-feuerstein-mims syndrome 10.5 HRAS KRAS
46 periampullary adenoma 10.5 HRAS KRAS
47 chordoma 10.5 CEACAM3 MUC1 S100B
48 bile duct cysts 10.5 HRAS KRAS
49 dendritic cell tumor 10.5 MUC1 S100B
50 reticular perineurioma 10.5 KIT MUC1 S100B

Graphical network of the top 20 diseases related to Aggressive Digital Papillary Adenocarcinoma:



Diseases related to Aggressive Digital Papillary Adenocarcinoma

Symptoms & Phenotypes for Aggressive Digital Papillary Adenocarcinoma

GenomeRNAi Phenotypes related to Aggressive Digital Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

26 (show all 24)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 9.91 HRAS MUC1 PIK3CA KRAS
2 Decreased viability GR00106-A-0 9.91 KRAS
3 Decreased viability GR00221-A-1 9.91 HRAS KIT PIK3CA KRAS
4 Decreased viability GR00221-A-2 9.91 HRAS PIK3CA KRAS
5 Decreased viability GR00221-A-3 9.91 HRAS
6 Decreased viability GR00221-A-4 9.91 PIK3CA
7 Decreased viability GR00301-A 9.91 KIT KRAS
8 Decreased viability GR00381-A-1 9.91 KRAS
9 Decreased viability GR00402-S-2 9.91 HRAS KIT MUC1 PIK3CA KRAS
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-117 9.86 KRAS
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.86 CEACAM3
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.86 KRAS
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-165 9.86 KIT CEACAM3 KRAS
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-18 9.86 KIT
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-193 9.86 KRAS
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.86 KRAS
17 Decreased shRNA abundance (Z-score < -2) GR00366-A-22 9.86 KRAS
18 Decreased shRNA abundance (Z-score < -2) GR00366-A-27 9.86 KRAS
19 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.86 KRAS
20 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.86 KRAS
21 Decreased shRNA abundance (Z-score < -2) GR00366-A-61 9.86 KIT
22 Decreased shRNA abundance (Z-score < -2) GR00366-A-66 9.86 KRAS
23 Decreased shRNA abundance (Z-score < -2) GR00366-A-72 9.86 CEACAM3
24 Decreased cell migration GR00055-A-1 9.46 MUC1 PIK3CA KRAS HRAS

MGI Mouse Phenotypes related to Aggressive Digital Papillary Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.1 HRAS KIT KRAS PDPN PIK3CA S100B

Drugs & Therapeutics for Aggressive Digital Papillary Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Aggressive Digital Papillary Adenocarcinoma

Genetic Tests for Aggressive Digital Papillary Adenocarcinoma

Anatomical Context for Aggressive Digital Papillary Adenocarcinoma

MalaCards organs/tissues related to Aggressive Digital Papillary Adenocarcinoma:

41
Lymph Node

Publications for Aggressive Digital Papillary Adenocarcinoma

Articles related to Aggressive Digital Papillary Adenocarcinoma:

(show all 42)
# Title Authors Year
1
The So-Called Aggressive Digital Papillary Adenocarcinoma Is Epithelial-Myoepithelial Carcinoma. ( 29384814 )
2018
2
Aggressive Digital Papillary Adenocarcinoma: Population-Based Analysis of Incidence, Demographics, Treatment, and Outcomes. ( 29578881 )
2018
3
Aggressive digital papillary adenocarcinoma: A clinicopathological study of 19 cases. ( 28495496 )
2017
4
Aggressive Digital Papillary Adenocarcinoma of the Hand Presenting as a Felon. ( 28421154 )
2017
5
Mohs Micrographic Surgery as a Digit-Sparing Treatment for Aggressive Digital Papillary Adenocarcinoma. ( 28291063 )
2017
6
Highly variable clinical feature and course of aggressive digital papillary adenocarcinoma. ( 29194742 )
2017
7
Aggressive digital papillary adenocarcinoma: treatment with Mohs micrographic surgery and an update of the literature. ( 28832985 )
2017
8
Aggressive Digital Papillary Adenocarcinoma With Multiple Organ Metastases: A Case Report and Review of the Literature. ( 27870729 )
2016
9
Papillary adnexal neoplasm (Aggressive digital papillary adenocarcinoma) on the ankle of a 15 year old girl: case report and review of literature from a pediatric perspective. ( 27535353 )
2016
10
Role of Radiotherapy in Aggressive Digital Papillary Adenocarcinoma. ( 27098633 )
2016
11
Aggressive Digital Papillary Adenocarcinoma: Case Report of a Positive Sentinel Lymph Node and Discussion of Utility of Sentinel Lymph Node Biopsy. ( 25954845 )
2015
12
Aggressive Digital Papillary Adenocarcinoma. ( 26576210 )
2015
13
Aggressive digital papillary adenocarcinoma - a rare malignant tumor of the sweat glands: two case reports and a review of the literature. ( 25848311 )
2015
14
Next-generation sequencing reveals rare genomic alterations in aggressive digital papillary adenocarcinoma. ( 26386519 )
2015
15
Aggressive Digital Papillary Adenocarcinoma-A rare Entity Posing a Diagnostic Challenge. ( 25977623 )
2014
16
Is aggressive digital papillary adenocarcinoma really aggressive digital papillary adenocarcinoma? ( 25126455 )
2014
17
Papillary eccrine adenoma should not be mistaken for aggressive digital papillary adenocarcinoma. ( 24274672 )
2013
18
A case report of a rare adnexal tumour: aggressive digital papillary adenocarcinoma. ( 24964471 )
2013
19
The medial plantar flap vascularized by the reverse flow lateral plantar artery: a novel variation through the case of aggressive digital papillary adenocarcinoma of the sole. ( 22711199 )
2012
20
Aggressive digital papillary adenocarcinoma of the hand: an unsuspected malignant tumour of the sweat glands. ( 22747355 )
2012
21
Aggressive digital papillary adenocarcinoma. ( 21330762 )
2011
22
Aggressive Digital Papillary Adenocarcinoma in a Young Female-a Rare Presentation. ( 22654416 )
2011
23
Aggressive digital papillary adenocarcinoma: a review. ( 19874325 )
2010
24
Aggressive digital papillary adenocarcinoma diagnosed by fine needle aspiration cytology. ( 21187879 )
2010
25
Human papillomavirus-58 and -73-associated digital squamous cell carcinoma in a patient with aggressive digital papillary adenocarcinoma. ( 19461243 )
2009
26
Aggressive digital papillary adenocarcinoma: a report of two diseases and review of the literature. ( 18819728 )
2009
27
Aggressive digital papillary adenocarcinoma on the palm with pulmonary metastases. ( 18705837 )
2008
28
Aggressive digital papillary adenocarcinoma of the hand. ( 17306428 )
2007
29
Aggressive digital papillary adenocarcinoma: a silent malignancy masquerading as acquired digital fibrokeratoma. ( 17645380 )
2007
30
Aggressive Digital Papillary Adenocarcinoma in a 15-year-old Female. ( 16912593 )
2006
31
Lymphatic mapping and sentinel lymph node biopsy for staging of aggressive digital papillary adenocarcinoma. ( 16462393 )
2006
32
Aggressive digital papillary adenocarcinoma presenting as a paronychia of the finger. ( 16055244 )
2005
33
Digital papillary adenoma (ADPA) and aggressive digital papillary adenocarcinoma (AdPACa). ( 16314709 )
2005
34
Metastatic aggressive digital papillary adenocarcinoma. ( 12953940 )
2003
35
An aggressive treatment for aggressive digital papillary adenocarcinoma. ( 11926336 )
2002
36
Aggressive digital papillary adenocarcinoma arising on the right great toe. ( 12370144 )
2002
37
Aggressive digital papillary adenocarcinoma presenting as finger infection. ( 12351985 )
2002
38
Aggressive digital papillary adenocarcinoma: a case report and review of the literature. ( 11285414 )
2001
39
Aggressive digital papillary adenocarcinoma of the foot: the clinicopathologic features of two cases. ( 11131478 )
2000
40
Sentinel node biopsy for staging of aggressive digital papillary adenocarcinoma. ( 10848941 )
2000
41
Aggressive digital papillary adenocarcinoma (aggressive digital papillary adenoma and adenocarcinoma revisited). ( 10843279 )
2000
42
Aggressive digital papillary adenocarcinoma. ( 2394851 )
1990

Variations for Aggressive Digital Papillary Adenocarcinoma

Expression for Aggressive Digital Papillary Adenocarcinoma

Search GEO for disease gene expression data for Aggressive Digital Papillary Adenocarcinoma.

Pathways for Aggressive Digital Papillary Adenocarcinoma

Pathways related to Aggressive Digital Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

(show all 50)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.96 CEACAM3 CEACAM5 HRAS KRAS PDPN PIK3CA
2
Show member pathways
12.74 HRAS KIT KRAS PIK3CA
3 12.7 HRAS KIT KRAS PIK3CA
4
Show member pathways
12.61 HRAS KIT KRAS PIK3CA
5
Show member pathways
12.56 HRAS KIT KRAS PIK3CA
6
Show member pathways
12.55 HRAS KIT KRAS PIK3CA
7
Show member pathways
12.26 HRAS KRAS MUC1 PIK3CA
8
Show member pathways
12.2 HRAS KRAS PIK3CA
9 12.18 HRAS KRAS PIK3CA
10 12.18 HRAS KRAS PIK3CA
11
Show member pathways
12.16 HRAS KRAS PIK3CA
12 12.09 HRAS KRAS PIK3CA
13
Show member pathways
12.09 HRAS KRAS PIK3CA
14
Show member pathways
12.06 HRAS KIT KRAS PIK3CA
15
Show member pathways
12.05 HRAS KIT PIK3CA
16
Show member pathways
12.05 HRAS KRAS PIK3CA
17 12.03 HRAS KRAS PIK3CA
18
Show member pathways
12.03 HRAS KRAS PIK3CA
19
Show member pathways
12 HRAS KRAS PIK3CA
20
Show member pathways
11.99 HRAS KRAS PIK3CA
21 11.92 HRAS KRAS PIK3CA
22
Show member pathways
11.91 HRAS KRAS PIK3CA
23
Show member pathways
11.89 HRAS KRAS PIK3CA
24 11.88 HRAS KRAS PIK3CA
25 11.86 HRAS KRAS PIK3CA
26
Show member pathways
11.83 HRAS KRAS PIK3CA
27 11.81 HRAS KRAS PIK3CA
28 11.79 CEACAM3 CEACAM5 KIT
29 11.78 HRAS KRAS PIK3CA
30 11.76 HRAS KRAS PIK3CA
31 11.75 HRAS KRAS PIK3CA
32 11.67 HRAS KRAS PIK3CA
33
Show member pathways
11.6 HRAS KRAS PIK3CA
34
Show member pathways
11.59 HRAS KRAS PIK3CA S100B
35
Show member pathways
11.56 HRAS KRAS PIK3CA
36
Show member pathways
11.38 HRAS KIT KRAS PIK3CA
37
Show member pathways
11.27 CEACAM3 CEACAM5 HRAS KRAS PIK3CA
38 11.2 HRAS PIK3CA
39 11.18 HRAS KRAS
40
Show member pathways
11.16 HRAS KRAS
41 11.13 HRAS PIK3CA
42 11.12 KRAS PIK3CA
43
Show member pathways
11.1 HRAS KRAS
44 11.07 HRAS KIT KRAS PIK3CA
45 11.03 HRAS KRAS
46 11 HRAS KRAS
47 10.97 HRAS KRAS PIK3CA
48 10.93 HRAS KRAS
49 10.88 HRAS PIK3CA
50 10.62 HRAS KRAS

GO Terms for Aggressive Digital Papillary Adenocarcinoma

Biological processes related to Aggressive Digital Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.81 HRAS KIT KRAS S100B
2 axon guidance GO:0007411 9.71 HRAS KRAS PIK3CA
3 Fc-epsilon receptor signaling pathway GO:0038095 9.7 HRAS KRAS PIK3CA
4 regulation of cell shape GO:0008360 9.67 KIT PDPN S100B
5 cytokine-mediated signaling pathway GO:0019221 9.67 KIT KRAS MUC1 PIK3CA
6 negative regulation of neuron apoptotic process GO:0043524 9.63 HRAS KRAS PIK3CA
7 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.58 HRAS KRAS MUC1
8 regulation of long-term neuronal synaptic plasticity GO:0048169 9.48 HRAS KRAS
9 negative regulation of anoikis GO:2000811 9.43 CEACAM5 PIK3CA
10 positive regulation of MAP kinase activity GO:0043406 9.43 HRAS KIT KRAS
11 epidermal growth factor receptor signaling pathway GO:0007173 9.33 HRAS KRAS PIK3CA
12 response to isolation stress GO:0035900 9.32 HRAS KRAS
13 ERBB2 signaling pathway GO:0038128 9.13 HRAS KRAS PIK3CA
14 leukocyte migration GO:0050900 9.02 CEACAM3 CEACAM5 HRAS KRAS PIK3CA

Sources for Aggressive Digital Papillary Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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