MCID: AGG003
MIFTS: 36

Aggressive Digital Papillary Adenocarcinoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Aggressive Digital Papillary Adenocarcinoma

MalaCards integrated aliases for Aggressive Digital Papillary Adenocarcinoma:

Name: Aggressive Digital Papillary Adenocarcinoma 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:5590

Summaries for Aggressive Digital Papillary Adenocarcinoma

MalaCards based summary : Aggressive Digital Papillary Adenocarcinoma is related to adenocarcinoma and paronychia. An important gene associated with Aggressive Digital Papillary Adenocarcinoma is MUC1 (Mucin 1, Cell Surface Associated), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Endometrial cancer. Affiliated tissues include skin, lung and liver, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 76 Aggressive digital papillary adenocarcinoma (also known as a digital papillary adenocarcinoma and... more...

Related Diseases for Aggressive Digital Papillary Adenocarcinoma

Diseases related to Aggressive Digital Papillary Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 171)
# Related Disease Score Top Affiliating Genes
1 adenocarcinoma 31.0 HRAS KIT KRAS MUC1 PIK3CA
2 paronychia 30.3 HRAS KRAS
3 squamous cell carcinoma 29.9 HRAS MUC1 PDPN PIK3CA
4 papillary adenocarcinoma 10.8
5 eccrine papillary adenocarcinoma 10.8
6 hemangiopericytoma, malignant 10.3 MUC1 S100B
7 intraneural perineurioma 10.3 MUC1 S100B
8 localized hypertrophic neuropathy 10.3 MUC1 S100B
9 sclerosing perineurioma 10.3 MUC1 S100B
10 intracranial cysts 10.3 MUC1 S100B
11 non-functioning pituitary adenoma 10.3 MUC1 S100B
12 functioning pituitary adenoma 10.3 MUC1 S100B
13 epithelioid malignant peripheral nerve sheath tumor 10.3 MUC1 S100B
14 ossifying fibromyxoid tumor 10.3 MUC1 S100B
15 sinonasal undifferentiated carcinoma 10.3 CEACAM3 MUC1
16 fibrous meningioma 10.3 MUC1 S100B
17 chordoid meningioma 10.3 MUC1 S100B
18 adenoma 10.3
19 eccrine porocarcinoma 10.2 MUC1 S100B
20 spindle cell rhabdomyosarcoma 10.2 MUC1 S100B
21 pseudomyxoma peritonei 10.2 KRAS MUC1
22 myxopapillary ependymoma 10.2 MUC1 S100B
23 monophasic synovial sarcoma 10.2 MUC1 S100B
24 chordoid glioma 10.2 MUC1 S100B
25 syringoma 10.2 MUC1 S100B
26 hidradenoma 10.2 MUC1 PIK3CA
27 pleomorphic liposarcoma 10.2 MUC1 S100B
28 anaplastic ependymoma 10.2 MUC1 S100B
29 rosette-forming glioneuronal tumor 10.2 PIK3CA S100B
30 sarcomatoid renal cell carcinoma 10.2 KIT MUC1
31 perivascular epithelioid cell tumor 10.2 KIT MUC1
32 rare adenocarcinoma of the breast 10.2 KRAS PIK3CA
33 papilloma of choroid plexus 10.2 MUC1 S100B
34 malignant dermis tumor 10.2 HRAS KIT
35 amelanotic melanoma 10.2 KIT S100B
36 spindle cell sarcoma 10.2 MUC1 S100B
37 prostate adenoid cystic carcinoma 10.2 HRAS PIK3CA
38 cecum adenocarcinoma 10.2 HRAS KRAS
39 thymoma, familial 10.2 HRAS KIT
40 ethmoid sinus cancer 10.2 HRAS PIK3CA
41 ethmoid sinus adenocarcinoma 10.2 HRAS PIK3CA
42 papillary hidradenoma 10.2 KIT PIK3CA
43 dermoid cyst 10.2 KIT MUC1
44 mast-cell leukemia 10.2 KIT PIK3CA
45 ovarian melanoma 10.2 HRAS KIT
46 villous adenoma 10.2 KRAS MUC1
47 papillary adenoma 10.2
48 rosai-dorfman disease 10.2 KRAS S100B
49 duodenal disease 10.2 KRAS MUC1
50 chordoma 10.2 CEACAM3 MUC1 S100B

Graphical network of the top 20 diseases related to Aggressive Digital Papillary Adenocarcinoma:



Diseases related to Aggressive Digital Papillary Adenocarcinoma

Symptoms & Phenotypes for Aggressive Digital Papillary Adenocarcinoma

GenomeRNAi Phenotypes related to Aggressive Digital Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

26 (show all 25)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 9.91 HRAS KRAS PIK3CA MUC1
2 Decreased viability GR00106-A-0 9.91 KRAS
3 Decreased viability GR00221-A-1 9.91 HRAS KIT KRAS PIK3CA
4 Decreased viability GR00221-A-2 9.91 HRAS KRAS PIK3CA
5 Decreased viability GR00221-A-3 9.91 HRAS
6 Decreased viability GR00221-A-4 9.91 PIK3CA
7 Decreased viability GR00301-A 9.91 KIT KRAS
8 Decreased viability GR00381-A-1 9.91 KRAS
9 Decreased viability GR00402-S-2 9.91 HRAS KIT KRAS PIK3CA MUC1
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-116 9.89 CEACAM3
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-117 9.89 KRAS
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.89 CEACAM3
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.89 KRAS
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-165 9.89 CEACAM3 KIT KRAS
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-18 9.89 KIT
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-193 9.89 KRAS
17 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.89 KRAS
18 Decreased shRNA abundance (Z-score < -2) GR00366-A-22 9.89 KRAS
19 Decreased shRNA abundance (Z-score < -2) GR00366-A-27 9.89 KRAS
20 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.89 KRAS
21 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.89 KRAS
22 Decreased shRNA abundance (Z-score < -2) GR00366-A-61 9.89 KIT
23 Decreased shRNA abundance (Z-score < -2) GR00366-A-66 9.89 KRAS
24 Decreased shRNA abundance (Z-score < -2) GR00366-A-72 9.89 CEACAM3
25 Decreased cell migration GR00055-A-1 9.46 HRAS KRAS MUC1 PIK3CA

MGI Mouse Phenotypes related to Aggressive Digital Papillary Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.1 HRAS KIT KRAS PDPN PIK3CA S100B

Drugs & Therapeutics for Aggressive Digital Papillary Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Aggressive Digital Papillary Adenocarcinoma

Genetic Tests for Aggressive Digital Papillary Adenocarcinoma

Anatomical Context for Aggressive Digital Papillary Adenocarcinoma

MalaCards organs/tissues related to Aggressive Digital Papillary Adenocarcinoma:

41
Skin, Lung, Liver, Colon, Breast, Pancreas, Thyroid

Publications for Aggressive Digital Papillary Adenocarcinoma

Articles related to Aggressive Digital Papillary Adenocarcinoma:

(show all 43)
# Title Authors Year
1
The So-Called Aggressive Digital Papillary Adenocarcinoma Is Epithelial-Myoepithelial Carcinoma. ( 29384814 )
2018
2
Aggressive Digital Papillary Adenocarcinoma: Population-Based Analysis of Incidence, Demographics, Treatment, and Outcomes. ( 29578881 )
2018
3
Gene expression profiling in aggressive digital papillary adenocarcinoma sheds light on the architecture of a rare sweat gland carcinoma. ( 30472730 )
2018
4
Aggressive digital papillary adenocarcinoma: A clinicopathological study of 19 cases. ( 28495496 )
2017
5
Aggressive Digital Papillary Adenocarcinoma of the Hand Presenting as a Felon. ( 28421154 )
2017
6
Mohs Micrographic Surgery as a Digit-Sparing Treatment for Aggressive Digital Papillary Adenocarcinoma. ( 28291063 )
2017
7
Highly variable clinical feature and course of aggressive digital papillary adenocarcinoma. ( 29194742 )
2017
8
Aggressive digital papillary adenocarcinoma: treatment with Mohs micrographic surgery and an update of the literature. ( 28832985 )
2017
9
Aggressive Digital Papillary Adenocarcinoma With Multiple Organ Metastases: A Case Report and Review of the Literature. ( 27870729 )
2016
10
Papillary adnexal neoplasm (Aggressive digital papillary adenocarcinoma) on the ankle of a 15 year old girl: case report and review of literature from a pediatric perspective. ( 27535353 )
2016
11
Role of Radiotherapy in Aggressive Digital Papillary Adenocarcinoma. ( 27098633 )
2016
12
Aggressive Digital Papillary Adenocarcinoma: Case Report of a Positive Sentinel Lymph Node and Discussion of Utility of Sentinel Lymph Node Biopsy. ( 25954845 )
2015
13
Aggressive Digital Papillary Adenocarcinoma. ( 26576210 )
2015
14
Aggressive digital papillary adenocarcinoma - a rare malignant tumor of the sweat glands: two case reports and a review of the literature. ( 25848311 )
2015
15
Next-generation sequencing reveals rare genomic alterations in aggressive digital papillary adenocarcinoma. ( 26386519 )
2015
16
Aggressive Digital Papillary Adenocarcinoma-A rare Entity Posing a Diagnostic Challenge. ( 25977623 )
2014
17
Is aggressive digital papillary adenocarcinoma really aggressive digital papillary adenocarcinoma? ( 25126455 )
2014
18
Papillary eccrine adenoma should not be mistaken for aggressive digital papillary adenocarcinoma. ( 24274672 )
2013
19
A case report of a rare adnexal tumour: aggressive digital papillary adenocarcinoma. ( 24964471 )
2013
20
The medial plantar flap vascularized by the reverse flow lateral plantar artery: a novel variation through the case of aggressive digital papillary adenocarcinoma of the sole. ( 22711199 )
2012
21
Aggressive digital papillary adenocarcinoma of the hand: an unsuspected malignant tumour of the sweat glands. ( 22747355 )
2012
22
Aggressive digital papillary adenocarcinoma. ( 21330762 )
2011
23
Aggressive Digital Papillary Adenocarcinoma in a Young Female-a Rare Presentation. ( 22654416 )
2011
24
Aggressive digital papillary adenocarcinoma: a review. ( 19874325 )
2010
25
Aggressive digital papillary adenocarcinoma diagnosed by fine needle aspiration cytology. ( 21187879 )
2010
26
Human papillomavirus-58 and -73-associated digital squamous cell carcinoma in a patient with aggressive digital papillary adenocarcinoma. ( 19461243 )
2009
27
Aggressive digital papillary adenocarcinoma: a report of two diseases and review of the literature. ( 18819728 )
2009
28
Aggressive digital papillary adenocarcinoma on the palm with pulmonary metastases. ( 18705837 )
2008
29
Aggressive digital papillary adenocarcinoma of the hand. ( 17306428 )
2007
30
Aggressive digital papillary adenocarcinoma: a silent malignancy masquerading as acquired digital fibrokeratoma. ( 17645380 )
2007
31
Aggressive Digital Papillary Adenocarcinoma in a 15-year-old Female. ( 16912593 )
2006
32
Lymphatic mapping and sentinel lymph node biopsy for staging of aggressive digital papillary adenocarcinoma. ( 16462393 )
2006
33
Aggressive digital papillary adenocarcinoma presenting as a paronychia of the finger. ( 16055244 )
2005
34
Digital papillary adenoma (ADPA) and aggressive digital papillary adenocarcinoma (AdPACa). ( 16314709 )
2005
35
Metastatic aggressive digital papillary adenocarcinoma. ( 12953940 )
2003
36
An aggressive treatment for aggressive digital papillary adenocarcinoma. ( 11926336 )
2002
37
Aggressive digital papillary adenocarcinoma arising on the right great toe. ( 12370144 )
2002
38
Aggressive digital papillary adenocarcinoma presenting as finger infection. ( 12351985 )
2002
39
Aggressive digital papillary adenocarcinoma: a case report and review of the literature. ( 11285414 )
2001
40
Aggressive digital papillary adenocarcinoma of the foot: the clinicopathologic features of two cases. ( 11131478 )
2000
41
Sentinel node biopsy for staging of aggressive digital papillary adenocarcinoma. ( 10848941 )
2000
42
Aggressive digital papillary adenocarcinoma (aggressive digital papillary adenoma and adenocarcinoma revisited). ( 10843279 )
2000
43
Aggressive digital papillary adenocarcinoma. ( 2394851 )
1990

Variations for Aggressive Digital Papillary Adenocarcinoma

Expression for Aggressive Digital Papillary Adenocarcinoma

Search GEO for disease gene expression data for Aggressive Digital Papillary Adenocarcinoma.

Pathways for Aggressive Digital Papillary Adenocarcinoma

Pathways related to Aggressive Digital Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

(show top 50) (show all 53)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.96 CEACAM3 CEACAM5 HRAS KRAS PDPN PIK3CA
2
Show member pathways
12.74 HRAS KIT KRAS PIK3CA
3 12.7 HRAS KIT KRAS PIK3CA
4
Show member pathways
12.6 HRAS KIT KRAS PIK3CA
5
Show member pathways
12.55 HRAS KIT KRAS PIK3CA
6
Show member pathways
12.54 HRAS KIT KRAS PIK3CA
7
Show member pathways
12.26 HRAS KRAS MUC1 PIK3CA
8
Show member pathways
12.24 HRAS KIT KRAS PIK3CA
9
Show member pathways
12.22 HRAS KRAS PIK3CA
10
Show member pathways
12.21 HRAS KRAS PIK3CA
11 12.19 HRAS KRAS PIK3CA
12 12.18 HRAS KRAS PIK3CA
13
Show member pathways
12.16 HRAS KRAS PIK3CA
14 12.1 HRAS KRAS PIK3CA
15
Show member pathways
12.09 HRAS KRAS PIK3CA
16
Show member pathways
12.07 HRAS KRAS PIK3CA
17
Show member pathways
12.06 HRAS KIT KRAS PIK3CA
18
Show member pathways
12.05 HRAS KIT PIK3CA
19 12.04 HRAS KRAS PIK3CA
20
Show member pathways
12.03 HRAS KRAS PIK3CA
21
Show member pathways
12.03 HRAS KRAS PIK3CA
22 12.02 HRAS KRAS PIK3CA
23
Show member pathways
11.99 HRAS KRAS PIK3CA
24
Show member pathways
11.99 HRAS KRAS PIK3CA
25 11.94 HRAS KRAS PIK3CA
26
Show member pathways
11.92 HRAS KRAS PIK3CA
27
Show member pathways
11.89 HRAS KRAS PIK3CA
28 11.88 HRAS KRAS PIK3CA
29 11.86 HRAS KRAS PIK3CA
30 11.81 HRAS KRAS PIK3CA
31 11.79 CEACAM3 CEACAM5 KIT
32 11.78 HRAS KRAS PIK3CA
33 11.76 HRAS KRAS PIK3CA
34 11.69 HRAS KRAS PIK3CA
35 11.67 HRAS KRAS PIK3CA
36
Show member pathways
11.6 HRAS KRAS PIK3CA
37
Show member pathways
11.59 HRAS KRAS PIK3CA S100B
38
Show member pathways
11.56 HRAS KRAS PIK3CA
39
Show member pathways
11.38 HRAS KIT KRAS PIK3CA
40
Show member pathways
11.27 CEACAM3 CEACAM5 HRAS KRAS PIK3CA
41 11.2 HRAS PIK3CA
42 11.18 HRAS KRAS
43
Show member pathways
11.16 HRAS KRAS
44 11.14 HRAS PIK3CA
45 11.12 KRAS PIK3CA
46
Show member pathways
11.1 HRAS KRAS
47 11.07 HRAS KIT KRAS PIK3CA
48 11.03 HRAS KRAS
49 11.01 HRAS KRAS
50 10.97 HRAS KRAS PIK3CA

GO Terms for Aggressive Digital Papillary Adenocarcinoma

Biological processes related to Aggressive Digital Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.78 HRAS KIT KRAS S100B
2 leukocyte migration GO:0050900 9.67 CEACAM3 CEACAM5 PIK3CA
3 regulation of cell shape GO:0008360 9.61 KIT PDPN S100B
4 negative regulation of neuron apoptotic process GO:0043524 9.58 HRAS KRAS PIK3CA
5 cytokine-mediated signaling pathway GO:0019221 9.56 KIT KRAS MUC1 PIK3CA
6 regulation of long-term neuronal synaptic plasticity GO:0048169 9.46 HRAS KRAS
7 negative regulation of anoikis GO:2000811 9.37 CEACAM5 PIK3CA
8 positive regulation of phospholipase C activity GO:0010863 9.32 HRAS KIT
9 response to isolation stress GO:0035900 9.16 HRAS KRAS
10 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.13 HRAS KRAS MUC1
11 positive regulation of MAP kinase activity GO:0043406 8.8 HRAS KIT KRAS

Sources for Aggressive Digital Papillary Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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