Agnosia disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: AGN002 MIFTS: 56	Agnosia Categories: Eye diseases, Mental diseases, Neuronal diseases, Rare diseases
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Aliases & Classifications for Agnosia

MalaCards integrated aliases for Agnosia:

Name: Agnosia ¹² ⁵³ ⁵⁴ ²⁹ ⁴⁴ ¹⁵ ⁷³

Primary Visual Agnosia ⁵³ ⁷³

Dyspraxia ¹² ⁵⁴

Apraxias ⁴⁴ ⁷³

Monomodal Visual Amnesia ⁵³

Dyspraxia Syndrome ¹²

Visual Amnesia ⁵³

Alexia ⁷³

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Mental diseases Eye diseases Neuronal diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Symptoms and signs involving speech and voice

Dyslexia and other symbolic dysfunctions, not elsewhere classified

Agnosia

Apraxia

External Ids:

Disease Ontology ¹² DOID:4090

ICD10 ³³ R48.1 R48.2

MeSH ⁴⁴ D000377 D001072

NCIt ⁵⁰ C84542

SNOMED-CT ⁶⁸ 42341009 68345001 6950007

UMLS ⁷³ C0001816 C0003635 C2930796 more

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Summaries for Agnosia

NIH Rare Diseases : ⁵³ Agnosia is characterized by an inability to recognize and identify objects and/or persons. Symptoms may vary, according to the area of the brain that is affected. It can be limited to one sensory modality such as vision or hearing; for example, a person may have difficulty in recognizing an object as a cup or identifying a sound as a cough. Agnosia can result from strokes, traumatic brain injury, dementia, a tumor, developmental disorders, overexposure to environmental toxins (e.g., carbon monoxide poisoning), or other neurological conditions. Visual agnosia may also occur in association with other underlying disorders. People with agnosia may retain their cognitive abilities in other areas. Treatment of primary agnosia is symptomatic and supportive; when it is caused by an underlying disorder, treatment of the disorder may reduce symptoms and help prevent further brain damage.

MalaCards based summary : Agnosia, also known as primary visual agnosia, is related to pain agnosia and withdrawal disorder, and has symptoms including seizures, fever and dyspnea. An important gene associated with Agnosia is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1), and among its related pathways/superpathways are Signaling by GPCR and Peptide ligand-binding receptors. The drugs Flurbiprofen and Dezocine have been mentioned in the context of this disorder. Affiliated tissues include brain, parietal lobe and eye, and related phenotypes are behavior/neurological and adipose tissue

Disease Ontology : ¹² A communication disorder that is a loss of ability to recognize objects, persons, sounds, shapes, or smells while the specific sense is not defective nor is there any significant memory loss.

NINDS : ⁵⁴ Agnosia is a rare disorder characterized by an inability to recognize and identify objects or persons. People with agnosia may have difficulty recognizing the geometric features of an object or face or may be able to perceive the geometric features but not know what the object is used for or whether a face is familiar or not. Agnosia can be limited to one sensory modality such as vision or hearing. For example, a person may have difficulty in recognizing an object as a cup or identifying a sound as a cough. Agnosia can result from strokes, dementia, developmental disorders, or other neurological conditions. It typically results from damage to specific brain areas in the occipital or parietal lobes of the brain. People with agnosia may retain their cognitive abilities in other areas.

Wikipedia : ⁷⁶ Agnosia is the inability to process sensory information. Often there is a loss of ability to recognize... more...

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Related Diseases for Agnosia

Diseases in the Agnosia family:

Form Agnosia

Diseases related to Agnosia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 288)

#	Related Disease	Score	Top Affiliating Genes
1	pain agnosia	31.4	AP1M2 AP2M1 CCK CNR1 HTR7 IER3IP1
2	withdrawal disorder	29.8	CNR1 HTR7 OPRM1 PDYN POMC
3	ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia	12.6
4	ocular motor apraxia	12.6
5	visual agnosia	12.5
6	auditory agnosia	12.5
7	apperceptive agnosia	12.5
8	ataxia-oculomotor apraxia 4	12.5
9	rolandic epilepsy, mental retardation, and speech dyspraxia, x-linked	12.4
10	tactile agnosia	12.4
11	verbal auditory agnosia	12.4
12	finger agnosia	12.4
13	developmental dyspraxia	12.4
14	ataxia-oculomotor apraxia 3	12.4
15	integrative agnosia	12.4
16	form agnosia	12.4
17	topographical agnosia	12.4
18	social emotional agnosia	12.3
19	associative agnosia	12.3
20	mirror agnosia	12.3
21	visual verbal agnosia	12.3
22	semantic agnosia	12.3
23	gait apraxia	12.2
24	time agnosia	12.2
25	color agnosia	12.2
26	apraxia of eyelid opening	12.1
27	primary progressive apraxia of speech	12.1
28	spinocerebellar ataxia, autosomal recessive 1	12.1
29	rolandic epilepsy-speech dyspraxia syndrome	12.0
30	astereognosia	12.0
31	autosomal recessive cerebellar ataxia-pyramidal signs-nystagmus-oculomotor apraxia syndrome	12.0
32	x-linked intellectual disability-ataxia-apraxia syndrome	12.0
33	spinocerebellar ataxia with axonal neuropathy type 2	11.8
34	epilepsy, focal, with speech disorder and with or without mental retardation	11.8
35	pilarowski-bjornsson syndrome	11.7
36	childhood apraxia of speech	11.7
37	autotopagnosia	11.6
38	developmental coordination disorder	11.5
39	poretti-boltshauser syndrome	11.5
40	birk-landau-perez syndrome	11.5
41	cortical deafness	11.5
42	gerstmann syndrome	11.5
43	prosopagnosia	11.5
44	galactosemia	11.4
45	ataxia-telangiectasia	11.3
46	apraxia	11.3
47	alexia	11.3
48	wieacker-wolff syndrome	11.3
49	phonagnosia	11.3
50	alexithymia	11.3

Graphical network of the top 20 diseases related to Agnosia:

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Symptoms & Phenotypes for Agnosia

UMLS symptoms related to Agnosia:

seizures, fever, dyspnea, edema, cachexia, vertigo, clumsiness, abnormality of extrapyramidal motor function, headache, torticollis, syncope, scanning speech, cyanosis, visual agnosia, muscle rigidity, icterus, signs and symptoms, signs and symptoms, digestive, other symbolic dysfunction, hot flushes, symptoms

MGI Mouse Phenotypes related to Agnosia:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	behavior/neurological	MP:0005386	9.7	CCK CNR1 HTR7 OPRL1 OPRM1 OXT
2	adipose tissue	MP:0005375	9.63	CNR1 OPRM1 OXT PDYN POMC TRPV1
3	integument	MP:0010771	9.32	CNR1 HTR7 OPRL1 OPRM1 OXT PDYN

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Drugs & Therapeutics for Agnosia

Drugs for Agnosia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 113)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Flurbiprofen

Approved, Investigational

Phase 4

5104-49-4

3394

Dezocine

Approved, Investigational

Phase 4

53648-55-8

3033053 40841

Dexmedetomidine

Approved, Vet_approved

Phase 4,Not Applicable

113775-47-6

68602 5311068

Nalbuphine

Approved

Phase 4

20594-83-6

5311304 5360630

Ketamine

Approved, Vet_approved

Phase 4

6740-88-1

3821

Morphine

Approved, Investigational

Phase 4,Phase 2,Phase 3,Not Applicable

57-27-2

5288826

Dexamethasone acetate

Approved, Investigational, Vet_approved

Phase 4,Not Applicable

1177-87-3

Acetaminophen

Approved

Phase 4,Phase 2,Phase 3,Not Applicable

103-90-2

1983

Dexamethasone

Approved, Investigational, Vet_approved

Phase 4,Not Applicable

50-02-2

5743

Levobupivacaine

Approved, Investigational

Phase 4,Not Applicable

27262-47-1

92253

Bupivacaine

Approved, Investigational

Phase 4,Not Applicable

2180-92-9, 38396-39-3

2474

Lidocaine

Approved, Vet_approved

Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable

137-58-6

3676

Ropivacaine

Approved

Phase 4,Phase 3,Not Applicable

84057-95-4

175805 71273

Oxycodone

Approved, Illicit, Investigational

Phase 4

76-42-6

5284603

Naloxone

Approved, Vet_approved

Phase 4

465-65-6

5284596

Gabapentin

Approved, Investigational

Phase 4

60142-96-3

3446

gamma-Aminobutyric acid

Approved, Investigational

Phase 4

56-12-2

119

Ibuprofen

Approved

Phase 4,Not Applicable

15687-27-1

3672

Clonidine

Approved

Phase 4

4205-90-7

2803

Tramadol

Approved, Investigational

Phase 4,Phase 3

27203-92-5

33741

Sufentanil

Approved, Investigational

Phase 4,Not Applicable

56030-54-7

41693

Remifentanil

Approved

Phase 4,Phase 3,Not Applicable

132875-61-7

60815

Ketoprofen

Approved, Vet_approved

Phase 4

22071-15-4

3825

Nefopam

Approved, Investigational

Phase 4

13669-70-0

Propofol

Approved, Investigational, Vet_approved

Phase 4,Phase 3

2078-54-8

4943

Cyclooxygenase Inhibitors

Phase 4,Not Applicable

Anti-Inflammatory Agents, Non-Steroidal

Phase 4,Not Applicable

Analgesics, Non-Narcotic

Phase 4,Phase 2,Phase 3,Not Applicable

Adrenergic Agents

Phase 4,Not Applicable

Adrenergic alpha-2 Receptor Agonists

Phase 4,Not Applicable

Peripheral Nervous System Agents

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

Hypnotics and Sedatives

Phase 4,Phase 3,Not Applicable

Adrenergic alpha-Agonists

Phase 4,Not Applicable

Narcotics

Phase 4,Phase 2,Phase 3,Not Applicable

Antirheumatic Agents

Phase 4,Not Applicable

Adrenergic Agonists

Phase 4,Not Applicable

Analgesics

Phase 4,Phase 2,Phase 3,Not Applicable

Analgesics, Opioid

Phase 4,Phase 2,Phase 3,Not Applicable

Neurotransmitter Agents

Phase 4,Not Applicable

Anti-Inflammatory Agents

Phase 4,Not Applicable

Central Nervous System Depressants

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

Anesthetics, Dissociative

Phase 4

Anesthetics, General

Phase 4,Phase 3,Not Applicable

Excitatory Amino Acid Antagonists

Phase 4,Not Applicable

Excitatory Amino Acids

Phase 4,Not Applicable

Anesthetics

Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable

Anesthetics, Intravenous

Phase 4,Phase 3,Not Applicable

Anesthetics, Local

Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable

BB 1101

Phase 4,Not Applicable

Antipyretics

Phase 4,Phase 2,Phase 3,Not Applicable

Interventional clinical trials:

(show top 50) (show all 69)

#	Name	Status	NCT ID	Phase	Drugs
1	Effect of Dexmedetomidine for Postoperative Intravenous Patient Controlled Analgesia	Unknown status	NCT03014713	Phase 4	Dezocine;Flubiprofen;Dexmedetomidine
2	Ketamine and Postoperative Analgesia in Children	Unknown status	NCT00200564	Phase 4	ketamine
3	Effects of Catheter Location on Postoperative Analgesia for Continuous Adductor Canal and Popliteal-Sciatic Nerve Blocks	Completed	NCT02523235	Phase 4	ropivacaine 0.2%
4	The Combination Effect of Dexmedetomidine and Morphine in Postoperative Patient-Controlled Analgesia	Completed	NCT00800826	Phase 4	dexmedetomidine
5	Early Postoperative Administration of Oxycodone +/- Naloxone and Duration of Epidural Analgesia	Completed	NCT02516059	Phase 4	oxycodone/naloxone;Oxycodone;Placebo
6	Multimodal Analgesic Treatment Versus Traditional Morphine Analgesia After Cardiac Surgery	Completed	NCT01966172	Phase 4	Ibuprofen;Gabapentin;Morphine;Paracetamol
7	Postoperative Pain and SIRS After Preoperative Analgesia With Clonidine or Levobupivacaine	Completed	NCT00860899	Phase 4	clonidine, levobupivacaine
8	Continuous Infusion of Dexamethasone Plus Tramadol Adjunct to Morphine PCA After Abdominal Hysterectomy	Completed	NCT00564603	Phase 4	Dexamethasone Sodium Phosphate Injection
9	Intravenous and Intraperitoneal Lignocaine for Perioperative Analgesia in Laparoscopic Colon Resections	Recruiting	NCT03105193	Phase 4	IV Saline bolus and infusion;IP Saline bolus and infusion;IV lignocaine bolus and infusion;IP Lignocaine bolus and infusion
10	Dexmedetomidine Supplemented Analgesia and 2-Year Survival After Cancer Surgery	Recruiting	NCT03012971	Phase 4	Dexmedetomidine supplemented morphine analgesia;Morphine analgesia
11	Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery.	Recruiting	NCT03007121	Phase 4	Morphine intrathecal;Bupivacaine + Sufentanil epidural;Morphine intravenous
12	Dexmedetomidine Supplemented Intravenous Analgesia in Elderly After Orthopedic Surgery	Recruiting	NCT03629262	Phase 4	Dexmedetomidine;Placebo
13	Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium	Recruiting	NCT03012984	Phase 4	Dexmedetomidine supplemented morphine analgesia;Morphine analgesia
14	Non-opioid Analgesic Combination With Morphine for Postoperative Analgesia.	Terminated	NCT01882530	Phase 4	Paracetamol;Nefopam;Ketoprofen;Morphine
15	A Study Comparing Two Analgesia/Sedation Regimens, Remifentanil/Propofol Versus Sufentanil/Propofol In Mechanically Ventilated Intensive Care Patients Requiring Analgesia And Sedation.	Terminated	NCT00421720	Phase 4	Sufentanil;Remifentanil
16	A PhaseⅡ/ Ⅲ Seamless Study to Evaluate Efficacy and Safety of Paracetamol Injection as Adjuvant to Morphine-based Postoperative Analgesia	Unknown status	NCT02811991	Phase 2, Phase 3	Paracetamol injection;Normal Saline injection;Morhpine PCA
17	Combination Analgesia for Neonatal Circumcision	Completed	NCT02990364	Phase 3	Sucrose;Lidocaine;EMLA Topical Product
18	Wound Infusion vs Spinal Morphine for Post-caesarean Analgesia	Completed	NCT02264821	Phase 3	ropivacaine infiltration;intrathecal morphine;placebo
19	Tramadol Versus Fentanyl for Post-Operative Analgesia in Newborn Infants	Completed	NCT00713726	Phase 3	FentanyL;Tramadol
20	Continuous Regional Analgesia After Total Knee Arthroplasty	Completed	NCT00337597	Phase 3
21	Pharmacoeconomic Consequences Of Analgesia in the Intensive Care Unit (ICU)	Terminated	NCT00436345	Phase 3	Remifentanil;Propofol
22	Development of a New Method for Analgesia	Completed	NCT00791024	Phase 1, Phase 2	CRC-Pharma 001;lidocaine suspension
23	Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia	Unknown status	NCT01739270	Not Applicable
24	Effect of N-methyl D-aspartate (NMDA) Receptor Antagonist Dextromethorphan on Opiods Analgesia and Tolerance in Pediatric Intensive Care Unit Patients	Unknown status	NCT01553435	Not Applicable	Dextromethorphan;Placebo
25	Do Epidurals Placed at a Lower Level Improve Labor Analgesia?	Unknown status	NCT00954317	Not Applicable
26	Depodur vs Fentanyl Infusion for Post-C/S Analgesia	Unknown status	NCT00762554	Not Applicable	Depodur;Depodur;Fentanyl
27	Low Level Laser (LED) Use to Increase Dental Implant Stability and Post Operative Analgesia	Unknown status	NCT01097499	Not Applicable
28	Effect of Thoracic Epidural Analgesia for Thoracotomy on the Occurrence of AF	Unknown status	NCT01718717	Not Applicable
29	Dietary Supplement for the Prevention of Cognitive Decline in a Very Elderly Population.	Unknown status	NCT01817101	Not Applicable
30	Perception and Multisensory Integration in Neurological Patients Using fMRI	Unknown status	NCT01469858	Not Applicable
31	Orientation Agnosia: Clinical and Anatomical Study	Completed	NCT01304576	Not Applicable
32	Newborn Cortical Response to Pain and Non Pharmacological Analgesia	Completed	NCT03389789	Not Applicable
33	Comparison of Patient-Controlled Analgesia With Different Background Infusion	Completed	NCT03221491	Not Applicable
34	Epidural Morphine for Postoperative Analgesia After Total Knee Arthroplasty	Completed	NCT03203967	Not Applicable	Intravenous morphine analgesia
35	Individualized Analgesia on Respiratory Adverse Events After Adenotonsillectomy	Completed	NCT02990910	Not Applicable	personalized opioid analgesia
36	A Randomised Controlled Trial Comparing Single Shot Adductor Canal Block With Local Infiltration Analgesia for Postoperative Analgesia After Total Knee Arthroplasty	Completed	NCT02104934	Not Applicable
37	μ-opioid Receptor Polymorphism and Opioid Analgesia	Completed	NCT02099877		Fentanyl
38	The Effect of Oxytocin on Placebo Analgesia: an Experimental Study in Healthy Volunteers	Completed	NCT01886014	Not Applicable	Oxytocin
39	Labour Analgesia and Movement in Babies	Completed	NCT01280084
40	The Randomised Epidural Analgesia in Term Delivering Women Trial (TREAT)	Completed	NCT01261689	Not Applicable	Ropivacaine/ Sufentanil according to local hospital protocol
41	Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia	Completed	NCT00487084	Not Applicable	Morphine-CP-saline (MCS);saline-2CP-morphine (SCM);saline-lidocaine-morphine (SLM)
42	Combined Implementation of Dural Puncture Epidural and Programmed Intermittent Epidural Bolus for Labor Analgesia	Completed	NCT03366935	Not Applicable
43	Individualized Timing of Analgesia and Effectiveness of Labor Analgesia	Completed	NCT02920489	Not Applicable	Individualized epidural analgesia;Routine epidural analgesia
44	Epidural Analgesia in Intensive Care Unit (APD-REA: Analgesie PeriDurale en REAnimation)	Completed	NCT01437358
45	Effects of Thoracic Epidural Analgesia and Surgery on Lower Urinary Tract Function: A Randomized, Controlled Study	Completed	NCT01220362	Not Applicable	Bupivacain 0.125%;Bupivacain 0.125%/Fentanyl 2mcg/ml
46	Surgical Stress Index as a Tool for Monitoring Analgesia and/or Sedation in Critically Ill Patients	Completed	NCT00789412
47	Telemedically Supported Analgesia in the Emergency Medical Service	Completed	NCT01644032	Not Applicable
48	Monitor-Guided Analgesia During General Anesthesia - Part I	Completed	NCT03303651	Not Applicable
49	Functional Magnetic Resonance Imaging (fMRI) of Anosognosia in Amnestic Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD)	Completed	NCT00908999
50	Neuraxial Labor Analgesia and the Incidence of Postpartum Depression	Completed	NCT02823418

Search NIH Clinical Center for Agnosia

Cochrane evidence based reviews: agnosia

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Genetic Tests for Agnosia

Genetic tests related to Agnosia:

#	Genetic test	Affiliating Genes
1	Agnosia ²⁹

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Anatomical Context for Agnosia

MalaCards organs/tissues related to Agnosia:

⁴¹

Brain, Parietal Lobe, Eye, Cortex, Temporal Lobe, Testes, Spinal Cord

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Publications for Agnosia

Articles related to Agnosia:

(show top 50) (show all 439)

#	Title	Authors	Year
1	Visual texture agnosia in dementia with Lewy bodies and Alzheimer's disease. ( 29673784 )	Oishi Y....Suzuki K.	2018
2	Agnosia Interferes With Daily Hygiene in Patients With Dementia. ( 29900188 )	Hamdy R.C....Whalen K.	2018
3	Agnosia for bird calls. ( 29572063 )	Muhammed L....Warren J.D.	2018
4	Agnosia ( 29630208 )	Kumar A....Dulebohn S.C.	2018
5	Association vs dissociation and setting appropriate criteria for object agnosia. ( 29658418 )	Garrido L....DeGutis J.	2018
6	Perceptual deficits of object identification: apperceptive agnosia. ( 29519462 )	Milner A.D....Cavina-Pratesi C.	2018
7	The neuropsychological rehabilitation of visual agnosia and Balint's syndrome. ( 29366371 )		2018
8	Apraxia, Neglect, and Agnosia. ( 29851877 )		2018
9	The contribution of facial dynamics to subtle expression recognition in typical viewers and developmental visual agnosia. ( 29723598 )		2018
10	Verbal auditory agnosia in a patient with traumatic brain injury: A case report. ( 29538212 )		2018
11	Should developmental prosopagnosia, developmental body agnosia, and developmental object agnosia be considered independent neurodevelopmental conditions? ( 29658410 )		2018
12	Supramodal agnosia for oblique mirror orientation in patients with periventricular leukomalacia. ( 29655042 )		2018
13	Neuromodulation of Right Auditory Cortex Selectively Increases Activation in Speech-Related Brain Areas in Brainstem Auditory Agnosia. ( 30239465 )	Bestelmeyer PEG...Rafal RD	2018
14	The painter from Sinaloa: artistic analysis of a case of spatial agnosia and neglect of visual shapes. ( 29185377 )	Orjuela-Rojas J.M....Leyva Townsend N.	2017
15	Relationship between somatosensory event-related potential N140 aberrations and hemispatial agnosia in patients with stroke: a preliminary study. ( 29076767 )	Ueno T....Yamada T.	2017
16	Impaired peripheral reaching and on-line corrections in patient DF: Optic ataxia with visual form agnosia. ( 28532578 )	Rossit S....McIntosh R.D.	2017
17	Landmark Agnosia: Evaluating the Definition of Landmark-based Navigation Impairment. ( 28164221 )	van der Ham I.J.M....van den Berg E.	2017
18	Auditory agnosia caused by bilateral putamen haemorrhage. ( 29269367 )	Sugiura T....Torii T.	2017
19	Pure Amorphagnosia without Tactile Object Agnosia. ( 28559827 )	Kubota S....Tsujihata M.	2017
20	Evidence of taxonomy for Developmental Topographical Disorientation: Developmental Landmark Agnosia Case 1. ( 29192795 )	Piccardi L....Pizzamiglio M.R.	2017
21	Stroke of the inferiomedial temporal lobe causing word agnosia. ( 28747411 )		2017
22	Visual agnosia and focal brain injury. ( 28843416 )		2017
23	Congenital prosopagnosia without object agnosia? A literature review. ( 29165034 )		2017
24	Preserved Expert Object Recognition in a Case of Unilateral Visual Agnosia. ( 28949822 )		2017
25	Poster 215 Gustatory Agnosia Following Herpes Simplex Virus Encephalitis: A Case Report. ( 27672976 )	Schultz S....Gater D.R.	2016
26	Impaired Velocity Processing Reveals an Agnosia for Motion in Depth. ( 27677897 )	Barendregt M....Rokers B.	2016
27	Enhancing Diversity in Academic Neurology: From Agnosia to Action. ( 26972163 )	Hamilton R.H.	2016
28	Pearls &amp; Oy-sters: Visual agnosia: An overlooked cortical sign. ( 27821572 )	Bergmans B....Bruffaerts R.	2016
29	Hurt but still alive: Residual activity in the parahippocampal cortex conditions the recognition of familiar places in a patient with topographic agnosia. ( 26909331 )	van Assche M....Assal F.	2016
30	Functional dissociation between action and perception of object shape in developmental visual object agnosia. ( 26827163 )		2016
31	Agnosia for head tremor in essential tremor: prevalence and clinical correlates. ( 26877883 )		2016
32	What's in the name 'alexithymia'? A commentary on &quot;Affective agnosia: Expansion of the alexithymia construct and a new opportunity to integrate and extend Freud's legacy.&quot;. ( 27235080 )		2016
33	Emotional quotient in frontotemporal dementia vs. Alzheimer's disease: the role of socioemotional agnosia. ( 27903133 )		2016
34	Pure word deafness with auditory object agnosia after bilateral lesion of the superior temporal sulcus. ( 26343343 )	Gutschalk A....Vogt-Schaden M.	2015
35	Emergence delirium with transient associative agnosia and expressive aphasia reversed by flumazenil in a pediatric patient. ( 26035220 )	Drobish J.K....Cook-Sather S.D.	2015
36	Intact implicit representation of object 3D structure in object agnosia. ( 26326787 )	Freud E....Behrmann M.	2015
37	Tactile Toe Agnosia and Percept of a &quot;Missing Toe&quot; in Healthy Humans. ( 26562866 )	Cicmil N....Stein J.F.	2015
38	Functional Mapping of the Human Auditory Cortex: fMRI Investigation of a Patient with Auditory Agnosia from Trauma to the Inferior Colliculus. ( 26413744 )	Poliva O....Rafal R.D.	2015
39	Real-time vision, tactile cues, and visual form agnosia: removing haptic feedback from a &quot;natural&quot; grasping task induces pantomime-like grasps. ( 25999834 )	Whitwell R.L....Goodale M.A.	2015
40	Auditory agnosia. ( 25726291 )	Robert Slevc L....Shell A.R.	2015
41	Reprint of: Visual processing of words in a patient with visual form agnosia: A behavioural and fMRI study. ( 26475097 )	Cavina-Pratesi C....Milner A.D.	2015
42	Visual agnosia. ( 26358494 )	A8lvarez R....Masjuan J.	2015
43	Visual processing of words in a patient with visual form agnosia: a behavioural and fMRI study. ( 25461705 )	Cavina-Pratesi C....Milner A.D.	2015
44	Affective agnosia: Expansion of the alexithymia construct and a new opportunity to integrate and extend Freud's legacy. ( 26054794 )		2015
45	Which visual functions depend on intermediate visual regions? Insights from a case of developmental visual form agnosia. ( 26209358 )		2015
46	Simultanagnosia and scene agnosia induced by right posterior cerebral artery infarction: a case report. ( 26369377 )		2015
47	Auditory agnosia as a clinical symptom of childhood adrenoleukodystrophy. ( 25544384 )	Furushima W...Inagaki M	2015
48	Psychosis, agnosia, and confabulation: an alternative two-factor account. ( 24328860 )	Turner M.A.	2014
49	Neurodegeneration and mirror image agnosia. ( 25317393 )	Chandra S.R....Issac T.G.	2014
50	Pure associative tactile agnosia for the left hand: clinical and anatomo-functional correlations. ( 25046697 )	Veronelli L....Corbo M.	2014

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Genes for Agnosia

Genes related to Agnosia (0 elite genes):

(show all 25)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	TRPV1	Transient Receptor Potential Cation Channel Subfamily V Member 1	Protein Coding	25.28	DISEASES inferred ¹⁵ ¹⁵
2	OPRM1	Opioid Receptor Mu 1	Protein Coding	18.92	DISEASES inferred ¹⁵
3	PDYN	Prodynorphin	Protein Coding	18.05	DISEASES inferred ¹⁵
4	POMC	Proopiomelanocortin	Protein Coding	17.97	DISEASES inferred ¹⁵
5	TAC1	Tachykinin Precursor 1	Protein Coding	17.72	DISEASES inferred ¹⁵
6	PSENEN	Presenilin Enhancer, Gamma-Secretase Subunit	Protein Coding	17.67	DISEASES inferred ¹⁵
7	OPRL1	Opioid Related Nociceptin Receptor 1	Protein Coding	17.66	DISEASES inferred ¹⁵
8	IER3IP1	Immediate Early Response 3 Interacting Protein 1	Protein Coding	17.42	DISEASES inferred ¹⁵ ¹⁵
9	CNR1	Cannabinoid Receptor 1	Protein Coding	17.4	DISEASES inferred ¹⁵
10	CCK	Cholecystokinin	Protein Coding	17.34	DISEASES inferred ¹⁵
11	HTR7	5-Hydroxytryptamine Receptor 7	Protein Coding	17.29	DISEASES inferred ¹⁵
12	LIPN	Lipase Family Member N	Protein Coding	17	DISEASES inferred ¹⁵
13	OXT	Oxytocin/Neurophysin I Prepropeptide	Protein Coding	8.9	DISEASES inferred ¹⁵
14	PNOC	Prepronociceptin	Protein Coding	7.91	DISEASES inferred ¹⁵
15	NPFF	Neuropeptide FF-Amide Peptide Precursor	Protein Coding	7.8	DISEASES inferred ¹⁵
16	TRIM13	Tripartite Motif Containing 13	Protein Coding	7.68	DISEASES inferred ¹⁵
17	RPL34	Ribosomal Protein L34	Protein Coding	7.65	DISEASES inferred ¹⁵
18	SLC22A18	Solute Carrier Family 22 Member 18	Protein Coding	7.6	DISEASES inferred ¹⁵
19	AP1M2	Adaptor Related Protein Complex 1 Subunit Mu 2	Protein Coding	7.21	DISEASES inferred ¹⁵
20	AP2M1	Adaptor Related Protein Complex 2 Subunit Mu 1	Protein Coding	7.06	DISEASES inferred ¹⁵
21	FOXP2	Forkhead Box P2	Protein Coding	6.88	DISEASES inferred ¹⁵
22	OPRK1	Opioid Receptor Kappa 1	Protein Coding	6.86	DISEASES inferred ¹⁵
23	FAAH	Fatty Acid Amide Hydrolase	Protein Coding	6.8	DISEASES inferred ¹⁵
24	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	6.76	DISEASES inferred ¹⁵
25	NTS	Neurotensin	Protein Coding	6.75	DISEASES inferred ¹⁵

Sources

Variations for Agnosia

Sources

Expression for Agnosia

Search GEO for disease gene expression data for Agnosia.

Sources

Pathways for Agnosia

Pathways related to Agnosia according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Signaling by GPCR ⁶⁶ Show member pathways GPCR downstream signaling ⁶⁶ Signal Transduction ⁶⁶	13.46	AP2M1 CCK CNR1 HTR7 NPFF OPRL1
2	Peptide ligand-binding receptors ⁶⁶ Show member pathways Class A/1 (Rhodopsin-like receptors) ⁶⁶ Defective AVP causes neurohypophyseal diabetes insipidus (NDI) ⁶⁶ Formyl peptide receptors bind formyl peptides and many other ligands ⁶⁶ G alpha (i) signalling events ⁶⁶ GPCR ligand binding ⁶⁶ GPCRs, Class A Rhodopsin-like ¹ Neuroactive ligand-receptor interaction ³⁷ Orexin and neuropeptides FF and QRFP bind to their respective receptors ⁶⁶ Peptide GPCRs ¹ Tachykinin receptors bind tachykinins ⁶⁶ Vasopressin-like receptors ⁶⁶	12.67	CCK CNR1 HTR7 NPFF OPRL1 OPRM1
3	Neuroscience ⁴	12.16	CNR1 OPRM1 POMC PSENEN
4	Syndecan-3-mediated signaling events ¹	10.49	POMC PSENEN
5	Cell-type Dependent Selectivity of CCK2R Signaling ¹	10.27	CCK CNR1

Sources

GO Terms for Agnosia

Cellular components related to Agnosia according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	perikaryon	GO:0043204	9.5	CCK NPFF OPRM1
2	neuronal cell body	GO:0043025	9.35	CCK PDYN PNOC TAC1 TRPV1
3	axon terminus	GO:0043679	9.33	NPFF PDYN PNOC
4	clathrin adaptor complex	GO:0030131	9.26	AP1M2 AP2M1
5	dendrite	GO:0030425	9.17	CCK HTR7 NPFF OPRM1 PDYN PNOC

Biological processes related to Agnosia according to GeneCards Suite gene sharing:

(show all 30)

#	Name	GO ID	Score	Top Affiliating Genes
1	regulation of signaling receptor activity	GO:0010469	9.93	CCK NPFF OXT PDYN PNOC POMC
2	G protein-coupled receptor signaling pathway	GO:0007186	9.9	CCK CNR1 HTR7 NPFF OPRL1 OPRM1
3	chemical synaptic transmission	GO:0007268	9.89	HTR7 NPFF PDYN PNOC TAC1
4	positive regulation of cytosolic calcium ion concentration	GO:0007204	9.84	NPFF OXT TAC1 TRPV1
5	memory	GO:0007613	9.78	CCK CNR1 OXT
6	excitatory postsynaptic potential	GO:0060079	9.76	NPFF OPRM1 TRPV1
7	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	GO:0007187	9.74	CNR1 HTR7 OPRM1
8	response to cocaine	GO:0042220	9.7	CNR1 OPRM1 OXT
9	negative regulation of blood pressure	GO:0045776	9.69	CNR1 OPRL1 OXT
10	response to morphine	GO:0043278	9.67	CNR1 NPFF OPRM1 TAC1
11	maternal process involved in female pregnancy	GO:0060135	9.65	CNR1 NPFF
12	sensory perception of pain	GO:0019233	9.65	CNR1 OPRL1 OPRM1 TAC1 TRPV1
13	response to food	GO:0032094	9.64	OPRM1 OXT
14	response to pain	GO:0048265	9.64	TAC1 TRPV1
15	estrous cycle	GO:0044849	9.63	OPRL1 OPRM1
16	positive regulation of ossification	GO:0045778	9.63	OXT TAC1
17	positive regulation of renal sodium excretion	GO:0035815	9.62	OXT TAC1
18	eating behavior	GO:0042755	9.62	CCK OPRL1 OPRM1 OXT
19	negative regulation of heart rate	GO:0010459	9.61	NPFF TAC1
20	positive regulation of blood pressure	GO:0045777	9.61	CNR1 NPFF OXT
21	negative regulation of appetite	GO:0032099	9.6	CCK NPFF
22	opioid receptor signaling pathway	GO:0038003	9.59	OPRL1 OPRM1
23	acute inflammatory response to antigenic stimulus	GO:0002438	9.58	NPFF OPRM1
24	sensory perception	GO:0007600	9.58	OPRL1 OPRM1 PNOC
25	positive regulation of sensory perception of pain	GO:1904058	9.56	CCK OPRL1
26	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO:0106072	9.55	OPRL1 OPRM1
27	positive regulation of gastric acid secretion	GO:0060454	9.48	OPRL1 TRPV1
28	regulation of sensory perception of pain	GO:0051930	9.35	CCK NPFF OPRL1 OPRM1 OXT
29	neuropeptide signaling pathway	GO:0007218	9.17	NPFF OPRL1 OPRM1 PDYN PNOC POMC
30	signal transduction	GO:0007165	10.22	CCK CNR1 HTR7 OPRL1 OPRM1 OXT

Molecular functions related to Agnosia according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	hormone activity	GO:0005179	9.43	CCK OXT POMC
2	neuropeptide binding	GO:0042923	9.32	OPRL1 OPRM1
3	opioid receptor activity	GO:0004985	9.16	OPRL1 OPRM1
4	opioid peptide activity	GO:0001515	8.96	PDYN PNOC
5	neuropeptide hormone activity	GO:0005184	8.92	CCK NPFF OXT PNOC

Sources

Sources for Agnosia

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia