MCID: AGN002
MIFTS: 62

Agnosia

Categories: Eye diseases, Mental diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Agnosia

MalaCards integrated aliases for Agnosia:

Name: Agnosia 12 54 55 30 45 15 17 74
Primary Visual Agnosia 54 74
Dyspraxia 12 55
Apraxias 45 74
Monomodal Visual Amnesia 54
Dyspraxia Syndrome 12
Visual Amnesia 54
Alexia 74

Classifications:



External Ids:

Disease Ontology 12 DOID:4090
NCIt 51 C84542
ICD10 34 R48.1 R48.2

Summaries for Agnosia

NIH Rare Diseases : 54 Agnosia is characterized by an inability to recognize and identify objects and/or persons. Symptoms may vary, according to the area of the brain that is affected. It can be limited to one sensory modality such as vision or hearing; for example, a person may have difficulty in recognizing an object as a cup or identifying a sound as a cough. Agnosia can result from strokes, traumatic brain injury, dementia, a tumor, developmental disorders, overexposure to environmental toxins (e.g., carbon monoxide poisoning), or other neurological conditions. Visual agnosia may also occur in association with other underlying disorders. People with agnosia may retain their cognitive abilities in other areas. Treatment of primary agnosia is symptomatic and supportive; when it is caused by an underlying disorder, treatment of the disorder may reduce symptoms and help prevent further brain damage.

MalaCards based summary : Agnosia, also known as primary visual agnosia, is related to pain agnosia and withdrawal disorder, and has symptoms including seizures, fever and dyspnea. An important gene associated with Agnosia is OPRM1 (Opioid Receptor Mu 1), and among its related pathways/superpathways are Signaling by GPCR and Peptide ligand-binding receptors. The drugs Dexmedetomidine and Dezocine have been mentioned in the context of this disorder. Affiliated tissues include brain, parietal lobe and cortex, and related phenotypes are behavior/neurological and homeostasis/metabolism

Disease Ontology : 12 A communication disorder that is a loss of ability to recognize objects, persons, sounds, shapes, or smells while the specific sense is not defective nor is there any significant memory loss.

NINDS : 55 Agnosia is a rare disorder characterized by an inability to recognize and identify objects or persons. People with agnosia may have difficulty recognizing the geometric features of an object or face or may be able to perceive the geometric features but not know what the object is used for or whether a face is familiar or not. Agnosia can be limited to one sensory modality such as vision or hearing. For example, a person may have difficulty in recognizing an object as a cup or identifying a sound as a cough. Agnosia can result from strokes, dementia, developmental disorders, or other neurological conditions. It typically results from damage to specific brain areas in the occipital or parietal lobes of the brain. People with agnosia may retain their cognitive abilities in other areas.

Wikipedia : 77 Agnosia is the inability to process sensory information. Often there is a loss of ability to recognize... more...

Related Diseases for Agnosia

Diseases in the Agnosia family:

Form Agnosia

Diseases related to Agnosia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 291)
# Related Disease Score Top Affiliating Genes
1 pain agnosia 31.0 CCK CNR1 LIPN NPFF OPRK1 OPRL1
2 withdrawal disorder 30.0 CNR1 OPRM1 PDYN POMC
3 ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia 12.7
4 ocular motor apraxia 12.6
5 auditory agnosia 12.6
6 visual agnosia 12.5
7 ataxia-oculomotor apraxia 4 12.5
8 apperceptive agnosia 12.5
9 rolandic epilepsy, mental retardation, and speech dyspraxia, x-linked 12.5
10 tactile agnosia 12.4
11 finger agnosia 12.4
12 ataxia-oculomotor apraxia 3 12.4
13 developmental dyspraxia 12.4
14 integrative agnosia 12.4
15 form agnosia 12.4
16 social emotional agnosia 12.4
17 verbal auditory agnosia 12.4
18 associative agnosia 12.4
19 topographical agnosia 12.3
20 mirror agnosia 12.3
21 visual verbal agnosia 12.3
22 semantic agnosia 12.3
23 gait apraxia 12.3
24 time agnosia 12.2
25 spinocerebellar ataxia, autosomal recessive 1 12.2
26 color agnosia 12.2
27 apraxia of eyelid opening 12.2
28 primary progressive apraxia of speech 12.1
29 rolandic epilepsy-speech dyspraxia syndrome 12.1
30 astereognosia 12.0
31 autosomal recessive cerebellar ataxia-pyramidal signs-nystagmus-oculomotor apraxia syndrome 12.0
32 intellectual disability-autism-speech apraxia-craniofacial dysmorphism syndrome 12.0
33 x-linked intellectual disability-ataxia-apraxia syndrome 12.0
34 epilepsy, focal, with speech disorder and with or without mental retardation 11.8
35 childhood apraxia of speech 11.7
36 pilarowski-bjornsson syndrome 11.7
37 autotopagnosia 11.6
38 poretti-boltshauser syndrome 11.5
39 birk-landau-perez syndrome 11.5
40 balint syndrome 11.5
41 developmental coordination disorder 11.5
42 cortical deafness 11.5
43 gerstmann syndrome 11.5
44 galactosemia 11.4
45 prosopagnosia 11.4
46 ataxia-telangiectasia 11.4
47 apraxia 11.4
48 alexia 11.4
49 wieacker-wolff syndrome 11.3
50 alzheimer disease 3 11.3

Graphical network of the top 20 diseases related to Agnosia:



Diseases related to Agnosia

Symptoms & Phenotypes for Agnosia

UMLS symptoms related to Agnosia:


seizures, fever, dyspnea, edema, cachexia, vertigo, clumsiness, abnormality of extrapyramidal motor function, headache, torticollis, syncope, scanning speech, cyanosis, visual agnosia, icterus, signs and symptoms, signs and symptoms, digestive, other symbolic dysfunction, hot flushes, muscle rigidity, symptoms

MGI Mouse Phenotypes related to Agnosia:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.1 ADRA2C CNR1 OPRD1 OPRK1 OPRL1 OPRM1
2 homeostasis/metabolism MP:0005376 10.07 ADRA2C CCK CNR1 LIPN OPRD1 OPRK1
3 integument MP:0010771 9.93 CNR1 OPRD1 OPRK1 OPRL1 OPRM1 OXT
4 adipose tissue MP:0005375 9.85 CNR1 OPRM1 OXT PDYN POMC TRPV1
5 nervous system MP:0003631 9.7 ADRA2C CCK CNR1 OPRD1 OPRK1 OPRL1
6 no phenotypic analysis MP:0003012 9.17 CCK CNR1 OPRD1 OPRM1 PDYN POMC

Drugs & Therapeutics for Agnosia

Drugs for Agnosia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 109)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexmedetomidine Approved, Vet_approved Phase 4,Not Applicable 113775-47-6 68602 5311068
2
Dezocine Approved, Investigational Phase 4 53648-55-8 40841 3033053
3
Flurbiprofen Approved, Investigational Phase 4 5104-49-4 3394
4
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
5
Nalbuphine Approved Phase 4 20594-83-6 5360630 5311304
6
Bupivacaine Approved, Investigational Phase 4,Not Applicable 2180-92-9, 38396-39-3 2474
7
Morphine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 57-27-2 5288826
8
Acetaminophen Approved Phase 4,Phase 2,Phase 3,Not Applicable 103-90-2 1983
9
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Not Applicable 50-02-2 5743
10
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Not Applicable 1177-87-3
11
Levobupivacaine Approved, Investigational Phase 4,Not Applicable 27262-47-1 92253
12
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 137-58-6 3676
13
Sufentanil Approved, Investigational Phase 4,Not Applicable 56030-54-7 41693
14
Ropivacaine Approved Phase 4,Phase 3,Not Applicable 84057-95-4 71273 175805
15
Naloxone Approved, Vet_approved Phase 4 465-65-6 5284596
16
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
17
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
18
Ibuprofen Approved Phase 4,Not Applicable 15687-27-1 3672
19
Clonidine Approved Phase 4 4205-90-7 2803
20
Tramadol Approved, Investigational Phase 4,Phase 3 27203-92-5 33741
21
Remifentanil Approved Phase 4,Phase 3,Not Applicable 132875-61-7 60815
22
Nefopam Approved, Investigational Phase 4 13669-70-0
23
Ketoprofen Approved, Vet_approved Phase 4 22071-15-4 3825
24
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3 2078-54-8 4943
25 Central Nervous System Depressants Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
26 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
27 Analgesics, Opioid Phase 4,Phase 2,Phase 3,Not Applicable
28 Anti-Inflammatory Agents Phase 4,Not Applicable
29 Adrenergic Agonists Phase 4,Not Applicable
30 Cyclooxygenase Inhibitors Phase 4,Not Applicable
31 Adrenergic alpha-2 Receptor Agonists Phase 4,Not Applicable
32 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Not Applicable
33 Neurotransmitter Agents Phase 4,Not Applicable
34 Narcotics Phase 4,Phase 2,Phase 3,Not Applicable
35 Adrenergic alpha-Agonists Phase 4,Not Applicable
36 Adrenergic Agents Phase 4,Not Applicable
37 Analgesics Phase 4,Phase 2,Phase 3,Not Applicable
38 Antirheumatic Agents Phase 4,Not Applicable
39 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 3,Not Applicable
40 Hypnotics and Sedatives Phase 4,Phase 3,Not Applicable
41 Excitatory Amino Acids Phase 4,Not Applicable
42 Anesthetics, General Phase 4,Phase 3,Not Applicable
43 Anesthetics, Intravenous Phase 4,Phase 3,Not Applicable
44 Anesthetics Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
45 Anesthetics, Dissociative Phase 4
46 Excitatory Amino Acid Antagonists Phase 4,Not Applicable
47 Anesthetics, Local Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
48 Adjuvants, Anesthesia Phase 4,Phase 3,Not Applicable
49 Antipyretics Phase 4,Phase 2,Phase 3,Not Applicable
50 BB 1101 Phase 4,Not Applicable

Interventional clinical trials:

(show top 50) (show all 71)
# Name Status NCT ID Phase Drugs
1 Effect of Dexmedetomidine for Postoperative Intravenous Patient Controlled Analgesia Unknown status NCT03014713 Phase 4 Dezocine;Flubiprofen;Dexmedetomidine
2 Ketamine and Postoperative Analgesia in Children Unknown status NCT00200564 Phase 4 ketamine
3 Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery. Completed NCT03007121 Phase 4 Morphine intrathecal;Bupivacaine + Sufentanil epidural;Morphine intravenous
4 Effects of Catheter Location on Postoperative Analgesia for Continuous Adductor Canal and Popliteal-Sciatic Nerve Blocks Completed NCT02523235 Phase 4 ropivacaine 0.2%
5 The Combination Effect of Dexmedetomidine and Morphine in Postoperative Patient-Controlled Analgesia Completed NCT00800826 Phase 4 dexmedetomidine
6 Early Postoperative Administration of Oxycodone +/- Naloxone and Duration of Epidural Analgesia Completed NCT02516059 Phase 4 oxycodone/naloxone;Oxycodone;Placebo
7 Multimodal Analgesic Treatment Versus Traditional Morphine Analgesia After Cardiac Surgery Completed NCT01966172 Phase 4 Ibuprofen;Gabapentin;Morphine;Paracetamol
8 Postoperative Pain and SIRS After Preoperative Analgesia With Clonidine or Levobupivacaine Completed NCT00860899 Phase 4 clonidine, levobupivacaine
9 Continuous Infusion of Dexamethasone Plus Tramadol Adjunct to Morphine PCA After Abdominal Hysterectomy Completed NCT00564603 Phase 4 Dexamethasone Sodium Phosphate Injection
10 Intravenous and Intraperitoneal Lignocaine for Perioperative Analgesia in Laparoscopic Colon Resections Recruiting NCT03105193 Phase 4 IV Saline bolus and infusion;IP Saline bolus and infusion;IV lignocaine bolus and infusion;IP Lignocaine bolus and infusion
11 Dexmedetomidine Supplemented Analgesia and 2-Year Survival After Cancer Surgery Recruiting NCT03012971 Phase 4 Dexmedetomidine supplemented morphine analgesia;Morphine analgesia
12 Dexmedetomidine Supplemented Intravenous Analgesia in Elderly After Orthopedic Surgery Recruiting NCT03629262 Phase 4 Dexmedetomidine;Placebo
13 Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium Recruiting NCT03012984 Phase 4 Dexmedetomidine supplemented morphine analgesia;Morphine analgesia
14 Non-opioid Analgesic Combination With Morphine for Postoperative Analgesia. Terminated NCT01882530 Phase 4 Paracetamol;Nefopam;Ketoprofen;Morphine
15 A Study Comparing Two Analgesia/Sedation Regimens, Remifentanil/Propofol Versus Sufentanil/Propofol In Mechanically Ventilated Intensive Care Patients Requiring Analgesia And Sedation. Terminated NCT00421720 Phase 4 Sufentanil;Remifentanil
16 A PhaseⅡ/ Ⅲ Seamless Study to Evaluate Efficacy and Safety of Paracetamol Injection as Adjuvant to Morphine-based Postoperative Analgesia Unknown status NCT02811991 Phase 2, Phase 3 Paracetamol injection;Normal Saline injection;Morhpine PCA
17 Combination Analgesia for Neonatal Circumcision Completed NCT02990364 Phase 3 Sucrose;Lidocaine;EMLA Topical Product
18 Wound Infusion vs Spinal Morphine for Post-caesarean Analgesia Completed NCT02264821 Phase 3 ropivacaine infiltration;intrathecal morphine;placebo
19 Tramadol Versus Fentanyl for Post-Operative Analgesia in Newborn Infants Completed NCT00713726 Phase 3 FentanyL;Tramadol
20 Continuous Regional Analgesia After Total Knee Arthroplasty Completed NCT00337597 Phase 3
21 Pharmacoeconomic Consequences Of Analgesia in the Intensive Care Unit (ICU) Terminated NCT00436345 Phase 3 Remifentanil;Propofol
22 Development of a New Method for Analgesia Completed NCT00791024 Phase 1, Phase 2 CRC-Pharma 001;lidocaine suspension
23 Protective Analgesia in Caesarean Section Using Intravenous Paracetamol Unknown status NCT03060265 Not Applicable Paracetamol;PLACEBO
24 Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia Unknown status NCT01739270 Not Applicable
25 Effect of N-methyl D-aspartate (NMDA) Receptor Antagonist Dextromethorphan on Opiods Analgesia and Tolerance in Pediatric Intensive Care Unit Patients Unknown status NCT01553435 Not Applicable Dextromethorphan;Placebo
26 Do Epidurals Placed at a Lower Level Improve Labor Analgesia? Unknown status NCT00954317 Not Applicable
27 Depodur vs Fentanyl Infusion for Post-C/S Analgesia Unknown status NCT00762554 Not Applicable Depodur;Depodur;Fentanyl
28 Low Level Laser (LED) Use to Increase Dental Implant Stability and Post Operative Analgesia Unknown status NCT01097499 Not Applicable
29 Effect of Thoracic Epidural Analgesia for Thoracotomy on the Occurrence of AF Unknown status NCT01718717 Not Applicable
30 Dietary Supplement for the Prevention of Cognitive Decline in a Very Elderly Population. Unknown status NCT01817101 Not Applicable
31 Perception and Multisensory Integration in Neurological Patients Using fMRI Unknown status NCT01469858 Not Applicable
32 Orientation Agnosia: Clinical and Anatomical Study Completed NCT01304576 Not Applicable
33 Newborn Cortical Response to Pain and Non Pharmacological Analgesia Completed NCT03389789 Not Applicable
34 Comparison of Patient-Controlled Analgesia With Different Background Infusion Completed NCT03221491 Not Applicable
35 Epidural Morphine for Postoperative Analgesia After Total Knee Arthroplasty Completed NCT03203967 Not Applicable Intravenous morphine analgesia
36 Individualized Analgesia on Respiratory Adverse Events After Adenotonsillectomy Completed NCT02990910 Not Applicable personalized opioid analgesia
37 A Randomised Controlled Trial Comparing Single Shot Adductor Canal Block With Local Infiltration Analgesia for Postoperative Analgesia After Total Knee Arthroplasty Completed NCT02104934 Not Applicable
38 μ-opioid Receptor Polymorphism and Opioid Analgesia Completed NCT02099877 Fentanyl
39 The Effect of Oxytocin on Placebo Analgesia: an Experimental Study in Healthy Volunteers Completed NCT01886014 Not Applicable Oxytocin
40 Labour Analgesia and Movement in Babies Completed NCT01280084
41 The Randomised Epidural Analgesia in Term Delivering Women Trial (TREAT) Completed NCT01261689 Not Applicable Ropivacaine/ Sufentanil according to local hospital protocol
42 Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia Completed NCT00487084 Not Applicable Morphine-CP-saline (MCS);saline-2CP-morphine (SCM);saline-lidocaine-morphine (SLM)
43 Combined Implementation of Dural Puncture Epidural and Programmed Intermittent Epidural Bolus for Labor Analgesia Completed NCT03366935 Not Applicable
44 Individualized Timing of Analgesia and Effectiveness of Labor Analgesia Completed NCT02920489 Not Applicable Individualized epidural analgesia;Routine epidural analgesia
45 Epidural Analgesia in Intensive Care Unit (APD-REA: Analgesie PeriDurale en REAnimation) Completed NCT01437358
46 Effects of Thoracic Epidural Analgesia and Surgery on Lower Urinary Tract Function: A Randomized, Controlled Study Completed NCT01220362 Not Applicable Bupivacain 0.125%;Bupivacain 0.125%/Fentanyl 2mcg/ml
47 Surgical Stress Index as a Tool for Monitoring Analgesia and/or Sedation in Critically Ill Patients Completed NCT00789412
48 Telemedically Supported Analgesia in the Emergency Medical Service Completed NCT01644032 Not Applicable
49 Monitor-Guided Analgesia During General Anesthesia - Part I Completed NCT03303651 Not Applicable
50 Functional Magnetic Resonance Imaging (fMRI) of Anosognosia in Amnestic Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) Completed NCT00908999

Search NIH Clinical Center for Agnosia

Cochrane evidence based reviews: agnosia

Genetic Tests for Agnosia

Genetic tests related to Agnosia:

# Genetic test Affiliating Genes
1 Agnosia 30

Anatomical Context for Agnosia

MalaCards organs/tissues related to Agnosia:

42
Brain, Parietal Lobe, Cortex, Temporal Lobe, Colon, Eye, Breast

Publications for Agnosia

Articles related to Agnosia:

(show top 50) (show all 442)
# Title Authors Year
1
Patient MW: transient visual hemi-agnosia. ( 30617908 )
2019
2
Visual texture agnosia in dementia with Lewy bodies and Alzheimer's disease. ( 29673784 )
2018
3
Agnosia Interferes With Daily Hygiene in Patients With Dementia. ( 29900188 )
2018
4
Agnosia for bird calls. ( 29572063 )
2018
5
Agnosia ( 29630208 )
2018
6
Association vs dissociation and setting appropriate criteria for object agnosia. ( 29658418 )
2018
7
Perceptual deficits of object identification: apperceptive agnosia. ( 29519462 )
2018
8
The neuropsychological rehabilitation of visual agnosia and Balint's syndrome. ( 29366371 )
2018
9
Apraxia, Neglect, and Agnosia. ( 29851877 )
2018
10
The contribution of facial dynamics to subtle expression recognition in typical viewers and developmental visual agnosia. ( 29723598 )
2018
11
Verbal auditory agnosia in a patient with traumatic brain injury: A case report. ( 29538212 )
2018
12
Should developmental prosopagnosia, developmental body agnosia, and developmental object agnosia be considered independent neurodevelopmental conditions? ( 29658410 )
2018
13
Supramodal agnosia for oblique mirror orientation in patients with periventricular leukomalacia. ( 29655042 )
2018
14
Neuromodulation of Right Auditory Cortex Selectively Increases Activation in Speech-Related Brain Areas in Brainstem Auditory Agnosia. ( 30239465 )
2018
15
Functional connectivity and the failure to retrieve meaning from shape in visual object agnosia. ( 30591372 )
2018
16
The painter from Sinaloa: artistic analysis of a case of spatial agnosia and neglect of visual shapes. ( 29185377 )
2017
17
Relationship between somatosensory event-related potential N140 aberrations and hemispatial agnosia in patients with stroke: a preliminary study. ( 29076767 )
2017
18
Impaired peripheral reaching and on-line corrections in patient DF: Optic ataxia with visual form agnosia. ( 28532578 )
2017
19
Landmark Agnosia: Evaluating the Definition of Landmark-based Navigation Impairment. ( 28164221 )
2017
20
Auditory agnosia caused by bilateral putamen haemorrhage. ( 29269367 )
2017
21
Pure Amorphagnosia without Tactile Object Agnosia. ( 28559827 )
2017
22
Evidence of taxonomy for Developmental Topographical Disorientation: Developmental Landmark Agnosia Case 1. ( 29192795 )
2017
23
Stroke of the inferiomedial temporal lobe causing word agnosia. ( 28747411 )
2017
24
Visual agnosia and focal brain injury. ( 28843416 )
2017
25
Congenital prosopagnosia without object agnosia? A literature review. ( 29165034 )
2017
26
Preserved Expert Object Recognition in a Case of Unilateral Visual Agnosia. ( 28949822 )
2017
27
Auditory agnosia associated with bilateral putaminal hemorrhage: A case report of clinical course of recovery. ( 28740065 )
2017
28
Poster 215 Gustatory Agnosia Following Herpes Simplex Virus Encephalitis: A Case Report. ( 27672976 )
2016
29
Impaired Velocity Processing Reveals an Agnosia for Motion in Depth. ( 27677897 )
2016
30
Enhancing Diversity in Academic Neurology: From Agnosia to Action. ( 26972163 )
2016
31
Pearls & Oy-sters: Visual agnosia: An overlooked cortical sign. ( 27821572 )
2016
32
Hurt but still alive: Residual activity in the parahippocampal cortex conditions the recognition of familiar places in a patient with topographic agnosia. ( 26909331 )
2016
33
Functional dissociation between action and perception of object shape in developmental visual object agnosia. ( 26827163 )
2016
34
Agnosia for head tremor in essential tremor: prevalence and clinical correlates. ( 26877883 )
2016
35
What's in the name 'alexithymia'? A commentary on "Affective agnosia: Expansion of the alexithymia construct and a new opportunity to integrate and extend Freud's legacy.". ( 27235080 )
2016
36
Emotional quotient in frontotemporal dementia vs. Alzheimer's disease: the role of socioemotional agnosia. ( 27903133 )
2016
37
Pure word deafness with auditory object agnosia after bilateral lesion of the superior temporal sulcus. ( 26343343 )
2015
38
Emergence delirium with transient associative agnosia and expressive aphasia reversed by flumazenil in a pediatric patient. ( 26035220 )
2015
39
Intact implicit representation of object 3D structure in object agnosia. ( 26326787 )
2015
40
Tactile Toe Agnosia and Percept of a "Missing Toe" in Healthy Humans. ( 26562866 )
2015
41
Functional Mapping of the Human Auditory Cortex: fMRI Investigation of a Patient with Auditory Agnosia from Trauma to the Inferior Colliculus. ( 26413744 )
2015
42
Real-time vision, tactile cues, and visual form agnosia: removing haptic feedback from a "natural" grasping task induces pantomime-like grasps. ( 25999834 )
2015
43
Auditory agnosia. ( 25726291 )
2015
44
Reprint of: Visual processing of words in a patient with visual form agnosia: A behavioural and fMRI study. ( 26475097 )
2015
45
Visual agnosia. ( 26358494 )
2015
46
Visual processing of words in a patient with visual form agnosia: a behavioural and fMRI study. ( 25461705 )
2015
47
Affective agnosia: Expansion of the alexithymia construct and a new opportunity to integrate and extend Freud's legacy. ( 26054794 )
2015
48
Which visual functions depend on intermediate visual regions? Insights from a case of developmental visual form agnosia. ( 26209358 )
2015
49
Simultanagnosia and scene agnosia induced by right posterior cerebral artery infarction: a case report. ( 26369377 )
2015
50
Psychosis, agnosia, and confabulation: an alternative two-factor account. ( 24328860 )
2014

Variations for Agnosia

Expression for Agnosia

Search GEO for disease gene expression data for Agnosia.

Pathways for Agnosia

GO Terms for Agnosia

Cellular components related to Agnosia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 axon GO:0030424 9.85 ADRA2C CCK CNR1 OPRM1 TAC1
2 neuronal cell body GO:0043025 9.73 CCK OPRK1 PDYN PNOC TAC1 TRPV1
3 perikaryon GO:0043204 9.67 CCK NPFF OPRK1 OPRM1
4 dendrite GO:0030425 9.5 CCK NPFF OPRK1 OPRM1 PDYN PNOC
5 integral component of presynaptic membrane GO:0099056 9.46 CNR1 OPRD1 OPRK1 OPRM1
6 integral component of postsynaptic membrane GO:0099055 9.43 OPRK1 OPRM1
7 spine apparatus GO:0097444 9.32 OPRD1 OPRM1
8 axon terminus GO:0043679 9.1 ADRA2C NPFF OPRD1 OPRK1 PDYN PNOC
9 plasma membrane GO:0005886 10.26 ADRA2C CNR1 OPRD1 OPRK1 OPRL1 OPRM1
10 integral component of plasma membrane GO:0005887 10.01 ADRA2C CNR1 OPRD1 OPRK1 OPRL1 OPRM1

Biological processes related to Agnosia according to GeneCards Suite gene sharing:

(show all 37)
# Name GO ID Score Top Affiliating Genes
1 chemical synaptic transmission GO:0007268 9.97 NPFF OPRK1 PDYN PNOC TAC1
2 positive regulation of cytosolic calcium ion concentration GO:0007204 9.88 NPFF OXT TAC1 TRPV1
3 response to ethanol GO:0045471 9.84 CNR1 OPRK1 OPRM1
4 female pregnancy GO:0007565 9.83 ADRA2C OXT PNOC
5 memory GO:0007613 9.81 CCK CNR1 OXT
6 excitatory postsynaptic potential GO:0060079 9.8 NPFF OPRM1 TRPV1
7 sensory perception of pain GO:0019233 9.8 CNR1 OPRK1 OPRL1 OPRM1 TAC1 TRPV1
8 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 9.79 CNR1 OPRD1 OPRM1
9 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0007193 9.78 OPRD1 OPRK1 OPRL1 OPRM1
10 phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 9.77 OPRD1 OPRK1 OPRM1
11 response to morphine GO:0043278 9.77 CNR1 NPFF OPRK1 OPRM1 TAC1
12 response to cocaine GO:0042220 9.76 CNR1 OPRK1 OPRM1 OXT
13 negative regulation of blood pressure GO:0045776 9.75 CNR1 OPRL1 OXT
14 sensory perception GO:0007600 9.73 OPRK1 OPRL1 OPRM1 PNOC
15 opioid receptor signaling pathway GO:0038003 9.71 OPRD1 OPRK1 OPRL1 OPRM1
16 positive regulation of blood pressure GO:0045777 9.7 CNR1 NPFF OXT
17 maternal process involved in female pregnancy GO:0060135 9.67 CNR1 NPFF
18 response to food GO:0032094 9.67 OPRM1 OXT
19 response to pain GO:0048265 9.67 TAC1 TRPV1
20 estrous cycle GO:0044849 9.67 OPRK1 OPRL1 OPRM1
21 positive regulation of ossification GO:0045778 9.65 OXT TAC1
22 positive regulation of renal sodium excretion GO:0035815 9.65 OXT TAC1
23 maternal behavior GO:0042711 9.65 OPRK1 OXT
24 negative regulation of heart rate GO:0010459 9.64 NPFF TAC1
25 behavior GO:0007610 9.63 OPRK1 OPRL1
26 negative regulation of appetite GO:0032099 9.63 CCK NPFF
27 eating behavior GO:0042755 9.63 CCK OPRD1 OPRK1 OPRL1 OPRM1 OXT
28 acute inflammatory response to antigenic stimulus GO:0002438 9.62 NPFF OPRM1
29 positive regulation of sensory perception of pain GO:1904058 9.61 CCK OPRL1
30 neuropeptide signaling pathway GO:0007218 9.61 NPFF OPRD1 OPRK1 OPRL1 OPRM1 PDYN
31 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0106072 9.59 OPRL1 OPRM1
32 adenylate cyclase-inhibiting opioid receptor signaling pathway GO:0031635 9.56 OPRK1 OPRM1
33 positive regulation of gastric acid secretion GO:0060454 9.55 OPRL1 TRPV1
34 regulation of sensory perception of pain GO:0051930 9.23 ADRA2C CCK NPFF OPRD1 OPRK1 OPRL1
35 signal transduction GO:0007165 10.21 ADRA2C CCK CNR1 OPRD1 OPRK1 OPRL1
36 G protein-coupled receptor signaling pathway GO:0007186 10.07 ADRA2C CCK CNR1 NPFF OPRD1 OPRK1
37 regulation of signaling receptor activity GO:0010469 10.01 CCK NPFF OXT PDYN PNOC POMC

Molecular functions related to Agnosia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.54 CCK OXT POMC
2 neuropeptide hormone activity GO:0005184 9.46 CCK NPFF OXT PNOC
3 receptor serine/threonine kinase binding GO:0033612 9.32 OPRD1 OPRK1
4 opioid peptide activity GO:0001515 9.26 PDYN PNOC
5 neuropeptide binding GO:0042923 9.26 OPRD1 OPRK1 OPRL1 OPRM1
6 opioid receptor activity GO:0004985 8.92 OPRD1 OPRK1 OPRL1 OPRM1

Sources for Agnosia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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