Agnosia disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: AGN002 MIFTS: 61	Agnosia Categories: Rare diseases, Mental diseases, Eye diseases
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Aliases & Classifications for Agnosia

MalaCards integrated aliases for Agnosia:

Name: Agnosia ¹² ⁵³ ²⁹ ⁴⁴ ¹⁵ ⁷³

Primary Visual Agnosia ⁵³ ⁷³

Dyspraxia ¹² ⁵⁴

Apraxias ⁴⁴ ⁷³

Monomodal Visual Amnesia ⁵³

Dyspraxia Syndrome ¹²

Visual Amnesia ⁵³

Alexia ⁷³

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Mental diseases Eye diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Symptoms and signs involving speech and voice

Dyslexia and other symbolic dysfunctions, not elsewhere classified

Agnosia

Apraxia

External Ids:

Disease Ontology ¹² DOID:4090

ICD10 ³³ R48.1 R48.2

MeSH ⁴⁴ D000377 D001072

NCIt ⁵⁰ C84542

SNOMED-CT ⁶⁸ 158320000 158322008 192146008 more

UMLS ⁷³ C0001816 C0003635

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Summaries for Agnosia

NIH Rare Diseases : ⁵³ Agnosia is characterized by an inability to recognize and identify objects and/or persons. Symptoms may vary, according to the area of the brain that is affected. It can be limited to one sensory modality such as vision or hearing; for example, a person may have difficulty in recognizing an object as a cup or identifying a sound as a cough. Agnosia can result from strokes, traumatic brain injury, dementia, a tumor, developmental disorders, overexposure to environmental toxins (e.g., carbon monoxide poisoning), or other neurological conditions. Visual agnosia may also occur in association with other underlying disorders. People with agnosia may retain their cognitive abilities in other areas. Treatment of primary agnosia is symptomatic and supportive; when it is caused by an underlying disorder, treatment of the disorder may reduce symptoms and help prevent further brain damage.

MalaCards based summary : Agnosia, also known as primary visual agnosia, is related to pain agnosia and visual agnosia, and has symptoms including cachexia, cyanosis and dyspnea. An important gene associated with Agnosia is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1), and among its related pathways/superpathways are Signaling by GPCR and Peptide ligand-binding receptors. The drugs Ketamine and Nalbuphine have been mentioned in the context of this disorder. Affiliated tissues include brain, parietal lobe and temporal lobe, and related phenotypes are behavior/neurological and homeostasis/metabolism

Disease Ontology : ¹² A communication disorder that is a loss of ability to recognize objects, persons, sounds, shapes, or smells while the specific sense is not defective nor is there any significant memory loss.

NINDS : ⁵⁴ Agnosia is a rare disorder characterized by an inability to recognize and identify objects or persons. People with agnosia may have difficulty recognizing the geometric features of an object or face or may be able to perceive the geometric features but not know what the object is used for or whether a face is familiar or not. Agnosia can be limited to one sensory modality such as vision or hearing. For example, a person may have difficulty in recognizing an object as a cup or identifying a sound as a cough. Agnosia can result from strokes, dementia, developmental disorders, or other neurological conditions. It typically results from damage to specific brain areas in the occipital or parietal lobes of the brain. People with agnosia may retain their cognitive abilities in other areas.

Wikipedia : ⁷⁶ Agnosia is the inability to process sensory information. Often there is a loss of ability to recognize... more...

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Related Diseases for Agnosia

Diseases in the Agnosia family:

Form Agnosia

Diseases related to Agnosia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 125)

#	Related Disease	Score	Top Affiliating Genes
1	pain agnosia	26.8	AP1M2 AP2M1 CCK CNR1 HTR7 LIPN
2	visual agnosia	12.4
3	auditory agnosia	12.3
4	apperceptive agnosia	12.3
5	rolandic epilepsy, mental retardation, and speech dyspraxia, x-linked	12.3
6	verbal auditory agnosia	12.3
7	finger agnosia	12.3
8	developmental dyspraxia	12.2
9	integrative agnosia	12.2
10	tactile agnosia	12.2
11	form agnosia	12.2
12	topographical agnosia	12.2
13	social emotional agnosia	12.2
14	associative agnosia	12.2
15	mirror agnosia	12.1
16	visual verbal agnosia	12.1
17	semantic agnosia	12.1
18	time agnosia	12.1
19	color agnosia	12.0
20	rolandic epilepsy-speech dyspraxia syndrome	11.9
21	astereognosia	11.8
22	autotopagnosia	11.4
23	cortical deafness	11.3
24	gerstmann syndrome	11.3
25	prosopagnosia	11.3
26	apraxia	11.2
27	alexia	11.2
28	phonagnosia	11.1
29	alexithymia	11.1
30	amusia	11.1
31	anosognosia	11.1
32	agraphia	11.1
33	simultanagnosia	11.1
34	myofascial pain syndrome	10.9	POMC TAC1
35	cyclic vomiting syndrome	10.9	CNR1 OPRM1
36	autoimmune encephalitis	10.9	CNR1 TRPV1
37	retrograde amnesia	10.9	PDYN POMC
38	epicondylitis	10.8	LIPN TAC1
39	stereotypic movement disorder	10.8	CCK TAC1
40	chronic pain	10.8	CNR1 OPRM1
41	somatoform disorder	10.8	OPRM1 TAC1 TRPV1
42	opioid abuse	10.8	CCK OPRM1 PDYN
43	neonatal abstinence syndrome	10.8	OPRK1 OPRM1
44	akinetopsia	10.8
45	kluver-bucy syndrome	10.8
46	nominal aphasia	10.8
47	semantic dementia	10.8
48	pancreas disease	10.7	CCK POMC TRPV1
49	sick building syndrome	10.7	POMC TRPV1
50	functional gastric disease	10.7	CCK HTR7 TRPV1

Graphical network of the top 20 diseases related to Agnosia:

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Symptoms & Phenotypes for Agnosia

UMLS symptoms related to Agnosia:

cachexia, cyanosis, dyspnea, edema, fever, headache, icterus, seizures, signs and symptoms, signs and symptoms, digestive, syncope, vertigo, visual agnosia, other symbolic dysfunction, hot flushes, scanning speech, muscle rigidity, torticollis, clumsiness, abnormality of extrapyramidal motor function, symptoms

MGI Mouse Phenotypes related to Agnosia:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	behavior/neurological	MP:0005386	10.03	OPRM1 OXT PDYN PNOC POMC TAC1
2	homeostasis/metabolism	MP:0005376	9.93	AP1M2 CCK CNR1 HTR7 LIPN OPRK1
3	adipose tissue	MP:0005375	9.8	CNR1 OPRM1 OXT PDYN POMC TRPV1
4	integument	MP:0010771	9.7	CNR1 HTR7 OPRK1 OPRL1 OPRM1 OXT
5	nervous system	MP:0003631	9.32	OPRL1 OPRM1 OXT PDYN POMC TRPV1

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Drugs & Therapeutics for Agnosia

Drugs for Agnosia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 113)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Ketamine

Approved, Vet_approved

Phase 4

6740-88-1

3821

Nalbuphine

Approved

Phase 4

20594-83-6

5360630 5311304

Morphine

Approved, Investigational

Phase 4,Phase 2,Phase 3,Not Applicable

57-27-2

5288826

Acetaminophen

Approved

Phase 4,Phase 2,Phase 3,Not Applicable

103-90-2

1983

Dexamethasone

Approved, Investigational, Vet_approved

Phase 4,Not Applicable

50-02-2

5743

Bupivacaine

Approved, Investigational

Phase 4,Not Applicable

2180-92-9, 38396-39-3

2474

Levobupivacaine

Approved, Investigational

Phase 4,Not Applicable

27262-47-1

92253

Lidocaine

Approved, Vet_approved

Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable

137-58-6

3676

Ropivacaine

Approved

Phase 4,Phase 3,Not Applicable

84057-95-4

71273 175805

Dexmedetomidine

Approved, Vet_approved

Phase 4

113775-47-6

68602 5311068

Naloxone

Approved, Vet_approved

Phase 4

465-65-6

5284596

Oxycodone

Approved, Illicit, Investigational

Phase 4

76-42-6

5284603

Gabapentin

Approved, Investigational

Phase 4

60142-96-3

3446

gamma-Aminobutyric acid

Approved, Investigational

Phase 4

56-12-2

119

Ibuprofen

Approved

Phase 4,Not Applicable

15687-27-1

3672

Clonidine

Approved

Phase 4

4205-90-7

2803

Tramadol

Approved, Investigational

Phase 4,Phase 3

27203-92-5

33741

Sufentanil

Approved, Investigational

Phase 4,Not Applicable

56030-54-7

41693

Dezocine

Approved, Investigational

Phase 4

53648-55-8

40841 3033053

Flurbiprofen

Approved, Investigational

Phase 4

5104-49-4

3394

Remifentanil

Approved

Phase 4,Phase 3,Not Applicable

132875-61-7

60815

Ketoprofen

Approved, Vet_approved

Phase 4

22071-15-4

3825

Nefopam

Approved, Investigational

Phase 4

13669-70-0

Propofol

Approved, Investigational, Vet_approved

Phase 4,Phase 3

2078-54-8

4943

Analgesics

Phase 4,Phase 2,Phase 3,Not Applicable

Anesthetics

Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable

Anesthetics, Dissociative

Phase 4

Anesthetics, General

Phase 4,Phase 3,Not Applicable

Anesthetics, Intravenous

Phase 4,Phase 3,Not Applicable

Central Nervous System Depressants

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

Excitatory Amino Acid Antagonists

Phase 4,Not Applicable

Excitatory Amino Acids

Phase 4,Not Applicable

Neurotransmitter Agents

Phase 4,Not Applicable

Peripheral Nervous System Agents

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

Anesthetics, Local

Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable

Analgesics, Non-Narcotic

Phase 4,Phase 2,Phase 3,Not Applicable

Analgesics, Opioid

Phase 4,Phase 2,Phase 3,Not Applicable

Narcotics

Phase 4,Phase 2,Phase 3,Not Applicable

Anti-Inflammatory Agents

Phase 4,Not Applicable

Antipyretics

Phase 4,Phase 2,Phase 3,Not Applicable

BB 1101

Phase 4,Not Applicable

Dexamethasone acetate

Phase 4,Not Applicable

1177-87-3

Autonomic Agents

Phase 4,Not Applicable

Antiemetics

Phase 4,Not Applicable

Antineoplastic Agents, Hormonal

Phase 4,Not Applicable

Gastrointestinal Agents

Phase 4,Not Applicable

glucocorticoids

Phase 4,Not Applicable

HIV Protease Inhibitors

Phase 4,Not Applicable

Hormone Antagonists

Phase 4,Not Applicable

Hormones

Phase 4,Not Applicable

Interventional clinical trials:

(show top 50) (show all 65)

#	Name	Status	NCT ID	Phase	Drugs
1	Ketamine and Postoperative Analgesia in Children	Unknown status	NCT00200564	Phase 4	ketamine
2	Effects of Catheter Location on Postoperative Analgesia for Continuous Adductor Canal and Popliteal-Sciatic Nerve Blocks	Completed	NCT02523235	Phase 4	ropivacaine 0.2%
3	The Combination Effect of Dexmedetomidine and Morphine in Postoperative Patient-Controlled Analgesia	Completed	NCT00800826	Phase 4	dexmedetomidine
4	Early Postoperative Administration of Oxycodone +/- Naloxone and Duration of Epidural Analgesia	Completed	NCT02516059	Phase 4	oxycodone/naloxone;Oxycodone;Placebo
5	Multimodal Analgesic Treatment Versus Traditional Morphine Analgesia After Cardiac Surgery	Completed	NCT01966172	Phase 4	Ibuprofen;Gabapentin;Morphine;Paracetamol
6	Postoperative Pain and SIRS After Preoperative Analgesia With Clonidine or Levobupivacaine	Completed	NCT00860899	Phase 4	clonidine, levobupivacaine
7	Continuous Infusion of Dexamethasone Plus Tramadol Adjunct to Morphine PCA After Abdominal Hysterectomy	Completed	NCT00564603	Phase 4	Dexamethasone Sodium Phosphate Injection
8	Effect of Dexmedetomidine for Postoperative Intravenous Patient Controlled Analgesia	Recruiting	NCT03014713	Phase 4	Dezocine;Flubiprofen;Dexmedetomidine
9	Dexmedetomidine Supplemented Analgesia and 2-Year Survival After Cancer Surgery	Recruiting	NCT03012971	Phase 4	Dexmedetomidine supplemented morphine analgesia;Morphine analgesia
10	Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium	Recruiting	NCT03012984	Phase 4	Dexmedetomidine supplemented morphine analgesia;Morphine analgesia
11	Intravenous and Intraperitoneal Lignocaine for Perioperative Analgesia in Laparoscopic Colon Resections	Not yet recruiting	NCT03105193	Phase 4	IV Saline bolus and infusion;IP Saline bolus and infusion;IV lignocaine bolus and infusion;IP Lignocaine bolus and infusion
12	Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery.	Not yet recruiting	NCT03007121	Phase 4	Morphine intrathecal;Bupivacaine + Sufentanil epidural;Morphine intravenous
13	Non-opioid Analgesic Combination With Morphine for Postoperative Analgesia.	Terminated	NCT01882530	Phase 4	Paracetamol;Nefopam;Ketoprofen;Morphine
14	A Study Comparing Two Analgesia/Sedation Regimens, Remifentanil/Propofol Versus Sufentanil/Propofol In Mechanically Ventilated Intensive Care Patients Requiring Analgesia And Sedation.	Terminated	NCT00421720	Phase 4	Sufentanil;Remifentanil
15	A PhaseⅡ/ Ⅲ Seamless Study to Evaluate Efficacy and Safety of Paracetamol Injection as Adjuvant to Morphine-based Postoperative Analgesia	Unknown status	NCT02811991	Phase 2, Phase 3	Paracetamol injection;Normal Saline injection;Morhpine PCA
16	Combination Analgesia for Neonatal Circumcision	Completed	NCT02990364	Phase 3	Sucrose;Lidocaine;EMLA Topical Product
17	Wound Infusion vs Spinal Morphine for Post-caesarean Analgesia	Completed	NCT02264821	Phase 3	ropivacaine infiltration;intrathecal morphine;placebo
18	Tramadol Versus Fentanyl for Post-Operative Analgesia in Newborn Infants	Completed	NCT00713726	Phase 3	FentanyL;Tramadol
19	Continuous Regional Analgesia After Total Knee Arthroplasty	Completed	NCT00337597	Phase 3
20	Pharmacoeconomic Consequences Of Analgesia in the Intensive Care Unit (ICU)	Terminated	NCT00436345	Phase 3	Remifentanil;Propofol
21	Development of a New Method for Analgesia	Completed	NCT00791024	Phase 1, Phase 2	CRC-Pharma 001;lidocaine suspension
22	Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia	Unknown status	NCT01739270	Not Applicable
23	Effect of N-methyl D-aspartate (NMDA) Receptor Antagonist Dextromethorphan on Opiods Analgesia and Tolerance in Pediatric Intensive Care Unit Patients	Unknown status	NCT01553435	Not Applicable	Dextromethorphan;Placebo
24	Do Epidurals Placed at a Lower Level Improve Labor Analgesia?	Unknown status	NCT00954317	Not Applicable
25	Depodur vs Fentanyl Infusion for Post-C/S Analgesia	Unknown status	NCT00762554	Not Applicable	Depodur;Depodur;Fentanyl
26	Low Level Laser (LED) Use to Increase Dental Implant Stability and Post Operative Analgesia	Unknown status	NCT01097499	Not Applicable
27	Effect of Thoracic Epidural Analgesia for Thoracotomy on the Occurrence of AF	Unknown status	NCT01718717	Not Applicable
28	Dietary Supplement for the Prevention of Cognitive Decline in a Very Elderly Population.	Unknown status	NCT01817101	Not Applicable
29	Perception and Multisensory Integration in Neurological Patients Using fMRI	Unknown status	NCT01469858	Not Applicable
30	Orientation Agnosia: Clinical and Anatomical Study	Completed	NCT01304576	Not Applicable
31	Newborn Cortical Response to Pain and Non Pharmacological Analgesia	Completed	NCT03389789	Not Applicable
32	Comparison of Patient-Controlled Analgesia With Different Background Infusion	Completed	NCT03221491	Not Applicable
33	Epidural Morphine for Postoperative Analgesia After Total Knee Arthroplasty	Completed	NCT03203967	Not Applicable	Intravenous morphine analgesia
34	Individualized Analgesia on Respiratory Adverse Events After Adenotonsillectomy	Completed	NCT02990910	Not Applicable	personalized opioid analgesia
35	A Randomised Controlled Trial Comparing Single Shot Adductor Canal Block With Local Infiltration Analgesia for Postoperative Analgesia After Total Knee Arthroplasty	Completed	NCT02104934	Not Applicable
36	μ-opioid Receptor Polymorphism and Opioid Analgesia	Completed	NCT02099877		Fentanyl
37	The Effect of Oxytocin on Placebo Analgesia: an Experimental Study in Healthy Volunteers	Completed	NCT01886014	Not Applicable	Oxytocin
38	Labour Analgesia and Movement in Babies	Completed	NCT01280084
39	The Randomised Epidural Analgesia in Term Delivering Women Trial (TREAT)	Completed	NCT01261689	Not Applicable	Ropivacaine/ Sufentanil according to local hospital protocol
40	Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia	Completed	NCT00487084	Not Applicable	Morphine-CP-saline (MCS);saline-2CP-morphine (SCM);saline-lidocaine-morphine (SLM)
41	Individualized Timing of Analgesia and Effectiveness of Labor Analgesia	Completed	NCT02920489	Not Applicable	Individualized epidural analgesia;Routine epidural analgesia
42	Epidural Analgesia in Intensive Care Unit (APD-REA: Analgesie PeriDurale en REAnimation)	Completed	NCT01437358
43	Effects of Thoracic Epidural Analgesia and Surgery on Lower Urinary Tract Function: A Randomized, Controlled Study	Completed	NCT01220362	Not Applicable	Bupivacain 0.125%;Bupivacain 0.125%/Fentanyl 2mcg/ml
44	Surgical Stress Index as a Tool for Monitoring Analgesia and/or Sedation in Critically Ill Patients	Completed	NCT00789412
45	Telemedically Supported Analgesia in the Emergency Medical Service	Completed	NCT01644032	Not Applicable
46	Monitor-Guided Analgesia During General Anesthesia - Part I	Completed	NCT03303651	Not Applicable
47	Functional Magnetic Resonance Imaging (fMRI) of Anosognosia in Amnestic Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD)	Completed	NCT00908999
48	Neuraxial Labor Analgesia and the Incidence of Postpartum Depression	Completed	NCT02823418
49	TAP vs Caudal Block Using Dexmedetomidine/ Bupivacaine for Post Operative Analgesia	Recruiting	NCT03482947	Not Applicable	ultrasonography-guided TAP block;Caudal epidural block
50	Perfusion Index and Labor Analgesia	Recruiting	NCT03107559

Search NIH Clinical Center for Agnosia

Cochrane evidence based reviews: agnosia

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Genetic Tests for Agnosia

Genetic tests related to Agnosia:

#	Genetic test	Affiliating Genes
1	Agnosia ²⁹

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Anatomical Context for Agnosia

MalaCards organs/tissues related to Agnosia:

⁴¹

Brain, Parietal Lobe, Temporal Lobe, Colon, Cortex, Eye, T Cells

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Publications for Agnosia

Articles related to Agnosia:

(show top 50) (show all 432)

#	Title	Authors	Year
1	Visual texture agnosia in dementia with Lewy bodies and Alzheimer's disease. ( 29673784 )	Oishi Y....Suzuki K.	2018
2	Agnosia Interferes With Daily Hygiene in Patients With Dementia. ( 29900188 )	Hamdy R.C....Whalen K.	2018
3	Agnosia for bird calls. ( 29572063 )	Muhammed L....Warren J.D.	2018
4	Agnosia ( 29630208 )	Kumar A....Dulebohn S.C.	2018
5	Association vs dissociation and setting appropriate criteria for object agnosia. ( 29658418 )	Garrido L....DeGutis J.	2018
6	Perceptual deficits of object identification: apperceptive agnosia. ( 29519462 )	Milner A.D....Cavina-Pratesi C.	2018
7	The neuropsychological rehabilitation of visual agnosia and Balint's syndrome. ( 29366371 )	Heutink J....Cordes C.	2018
8	Apraxia, Neglect, and Agnosia. ( 29851877 )	Coslett H.B.	2018
9	The contribution of facial dynamics to subtle expression recognition in typical viewers and developmental visual agnosia. ( 29723598 )	Yitzhak N....Aviezer H.	2018
10	Verbal auditory agnosia in a patient with traumatic brain injury: A case report. ( 29538212 )	Kim J.M....Park D.	2018
11	Should developmental prosopagnosia, developmental body agnosia, and developmental object agnosia be considered independent neurodevelopmental conditions? ( 29658410 )	Gray K.L.H....Cook R.	2018
12	Supramodal agnosia for oblique mirror orientation in patients with periventricular leukomalacia. ( 29655042 )	Castaldi E....Morrone M.C.	2018
13	The painter from Sinaloa: artistic analysis of a case of spatial agnosia and neglect of visual shapes. ( 29185377 )	Orjuela-Rojas J.M....Leyva Townsend N.	2017
14	Relationship between somatosensory event-related potential N140 aberrations and hemispatial agnosia in patients with stroke: a preliminary study. ( 29076767 )	Ueno T....Yamada T.	2017
15	Impaired peripheral reaching and on-line corrections in patient DF: Optic ataxia with visual form agnosia. ( 28532578 )	Rossit S....McIntosh R.D.	2017
16	Landmark Agnosia: Evaluating the Definition of Landmark-based Navigation Impairment. ( 28164221 )	van der Ham I.J.M....van den Berg E.	2017
17	Auditory agnosia caused by bilateral putamen haemorrhage. ( 29269367 )	Sugiura T....Torii T.	2017
18	Pure Amorphagnosia without Tactile Object Agnosia. ( 28559827 )	Kubota S....Tsujihata M.	2017
19	Evidence of taxonomy for Developmental Topographical Disorientation: Developmental Landmark Agnosia Case 1. ( 29192795 )	Piccardi L....Pizzamiglio M.R.	2017
20	Stroke of the inferiomedial temporal lobe causing word agnosia. ( 28747411 )	Hassan H....Pattanshetti M.	2017
21	Visual agnosia and focal brain injury. ( 28843416 )	Martinaud O.	2017
22	Congenital prosopagnosia without object agnosia? A literature review. ( 29165034 )	Geskin J....Behrmann M.	2017
23	Preserved Expert Object Recognition in a Case of Unilateral Visual Agnosia. ( 28949822 )	Rennig J....Karnath H.O.	2017
24	Auditory agnosia associated with bilateral putaminal hemorrhage: A case report of clinical course of recovery. ( 28740065 )	Tokida H....Kuriyama M.	2017
25	Poster 215 Gustatory Agnosia Following Herpes Simplex Virus Encephalitis: A Case Report. ( 27672976 )	Schultz S....Gater D.R.	2016
26	Impaired Velocity Processing Reveals an Agnosia for Motion in Depth. ( 27677897 )	Barendregt M....Rokers B.	2016
27	Enhancing Diversity in Academic Neurology: From Agnosia to Action. ( 26972163 )	Hamilton R.H.	2016
28	Pearls &amp; Oy-sters: Visual agnosia: An overlooked cortical sign. ( 27821572 )	Bergmans B....Bruffaerts R.	2016
29	Hurt but still alive: Residual activity in the parahippocampal cortex conditions the recognition of familiar places in a patient with topographic agnosia. ( 26909331 )	van Assche M....Assal F.	2016
30	Functional dissociation between action and perception of object shape in developmental visual object agnosia. ( 26827163 )	Freud E....Gilaie-Dotan S.	2016
31	Agnosia for head tremor in essential tremor: prevalence and clinical correlates. ( 26877883 )	Eken H.N....Louis E.D.	2016
32	What's in the name 'alexithymia'? A commentary on &quot;Affective agnosia: Expansion of the alexithymia construct and a new opportunity to integrate and extend Freud's legacy.&quot;. ( 27235080 )	Taylor G.J....Parker J.D.	2016
33	Emotional quotient in frontotemporal dementia vs. Alzheimer's disease: the role of socioemotional agnosia. ( 27903133 )	Carr A.R....Mendez M.F.	2016
34	Pure word deafness with auditory object agnosia after bilateral lesion of the superior temporal sulcus. ( 26343343 )	Gutschalk A....Vogt-Schaden M.	2015
35	Emergence delirium with transient associative agnosia and expressive aphasia reversed by flumazenil in a pediatric patient. ( 26035220 )	Drobish J.K....Cook-Sather S.D.	2015
36	Intact implicit representation of object 3D structure in object agnosia. ( 26326787 )	Freud E....Behrmann M.	2015
37	Tactile Toe Agnosia and Percept of a &quot;Missing Toe&quot; in Healthy Humans. ( 26562866 )	Cicmil N....Stein J.F.	2015
38	Functional Mapping of the Human Auditory Cortex: fMRI Investigation of a Patient with Auditory Agnosia from Trauma to the Inferior Colliculus. ( 26413744 )	Poliva O....Rafal R.D.	2015
39	Real-time vision, tactile cues, and visual form agnosia: removing haptic feedback from a &quot;natural&quot; grasping task induces pantomime-like grasps. ( 25999834 )	Whitwell R.L....Goodale M.A.	2015
40	Auditory agnosia. ( 25726291 )	Robert Slevc L....Shell A.R.	2015
41	Reprint of: Visual processing of words in a patient with visual form agnosia: A behavioural and fMRI study. ( 26475097 )	Cavina-Pratesi C....Milner A.D.	2015
42	Visual agnosia. ( 26358494 )	A8lvarez R....Masjuan J.	2015
43	Visual processing of words in a patient with visual form agnosia: a behavioural and fMRI study. ( 25461705 )	Cavina-Pratesi C....Milner A.D.	2015
44	Affective agnosia: Expansion of the alexithymia construct and a new opportunity to integrate and extend Freud's legacy. ( 26054794 )	Lane R.D....Smith R.	2015
45	Which visual functions depend on intermediate visual regions? Insights from a case of developmental visual form agnosia. ( 26209358 )	Gilaie-Dotan S.	2015
46	Simultanagnosia and scene agnosia induced by right posterior cerebral artery infarction: a case report. ( 26369377 )	Kobayashi Y....Miura T.	2015
47	Psychosis, agnosia, and confabulation: an alternative two-factor account. ( 24328860 )	Turner M.A.	2014
48	Neurodegeneration and mirror image agnosia. ( 25317393 )	Chandra S.R....Issac T.G.	2014
49	Pure associative tactile agnosia for the left hand: clinical and anatomo-functional correlations. ( 25046697 )	Veronelli L....Corbo M.	2014
50	Visual object agnosia is associated with a breakdown of object-selective responses in the lateral occipital cortex. ( 24863251 )	Ptak R....Simon S.R.	2014

Sources

Genes for Agnosia

Genes related to Agnosia (0 elite genes):

(show all 25)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	TRPV1	Transient Receptor Potential Cation Channel Subfamily V Member 1	Protein Coding	25.28	DISEASES inferred ¹⁵ ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	OPRM1	Opioid Receptor Mu 1	Protein Coding	18.96	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	PDYN	Prodynorphin	Protein Coding	18.13	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	POMC	Proopiomelanocortin	Protein Coding	18.02	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
5	TAC1	Tachykinin Precursor 1	Protein Coding	17.8	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	OPRL1	Opioid Related Nociceptin Receptor 1	Protein Coding	17.71	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
7	PSENEN	Presenilin Enhancer, Gamma-Secretase Subunit	Protein Coding	17.7	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
8	CNR1	Cannabinoid Receptor 1	Protein Coding	17.41	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
9	CCK	Cholecystokinin	Protein Coding	17.38	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
10	HTR7	5-Hydroxytryptamine Receptor 7	Protein Coding	17.32	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
11	LIPN	Lipase Family Member N	Protein Coding	17.12	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
12	OPRK1	Opioid Receptor Kappa 1	Protein Coding	16.93	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
13	OXT	Oxytocin/Neurophysin I Prepropeptide	Protein Coding	8.93	DISEASES inferred ¹⁵
14	PNOC	Prepronociceptin	Protein Coding	7.96	DISEASES inferred ¹⁵
15	NPFF	Neuropeptide FF-Amide Peptide Precursor	Protein Coding	7.84	DISEASES inferred ¹⁵
16	TRIM13	Tripartite Motif Containing 13	Protein Coding	7.73	DISEASES inferred ¹⁵
17	RPL34	Ribosomal Protein L34	Protein Coding	7.7	DISEASES inferred ¹⁵
18	SLC22A18	Solute Carrier Family 22 Member 18	Protein Coding	7.66	DISEASES inferred ¹⁵
19	AP1M2	Adaptor Related Protein Complex 1 Subunit Mu 2	Protein Coding	7.28	DISEASES inferred ¹⁵
20	AP2M1	Adaptor Related Protein Complex 2 Subunit Mu 1	Protein Coding	7.14	DISEASES inferred ¹⁵
21	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	6.86	DISEASES inferred ¹⁵
22	NTS	Neurotensin	Protein Coding	6.85	DISEASES inferred ¹⁵
23	APTX	Aprataxin	Protein Coding	6.83	DISEASES inferred ¹⁵
24	PTGS2	Prostaglandin-Endoperoxide Synthase 2	Protein Coding	6.83	DISEASES inferred ¹⁵
25	IER3IP1	Immediate Early Response 3 Interacting Protein 1	Protein Coding	6.82	DISEASES inferred ¹⁵ ¹⁵

Sources

Variations for Agnosia

Sources

Expression for Agnosia

Search GEO for disease gene expression data for Agnosia.

Sources

Pathways for Agnosia

Pathways related to Agnosia according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Signaling by GPCR ⁶⁶ Show member pathways GPCR downstream signaling ⁶⁶ Signal Transduction ⁶⁶	13.5	AP2M1 CCK CNR1 HTR7 NPFF OPRK1
2	Peptide ligand-binding receptors ⁶⁶ Show member pathways Class A/1 (Rhodopsin-like receptors) ⁶⁶ Defective AVP causes neurohypophyseal diabetes insipidus (NDI) ⁶⁶ Formyl peptide receptors bind formyl peptides and many other ligands ⁶⁶ G alpha (i) signalling events ⁶⁶ GPCR ligand binding ⁶⁶ GPCRs, Class A Rhodopsin-like ¹ Neuroactive ligand-receptor interaction ³⁷ Orexin and neuropeptides FF and QRFP bind to their respective receptors ⁶⁶ Peptide GPCRs ¹ Tachykinin receptors bind tachykinins ⁶⁶ Vasopressin-like receptors ⁶⁶	12.7	CCK CNR1 HTR7 NPFF OPRK1 OPRL1
3	Neuroscience ⁴	12.16	CNR1 OPRM1 POMC PSENEN
4	Syndecan-3-mediated signaling events ¹	10.49	POMC PSENEN
5	Cell-type Dependent Selectivity of CCK2R Signaling ¹	10.27	CCK CNR1

Sources

GO Terms for Agnosia

Cellular components related to Agnosia according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	integral component of plasma membrane	GO:0005887	9.98	CNR1 HTR7 OPRK1 OPRL1 OPRM1 PSENEN
2	axon	GO:0030424	9.76	CCK CNR1 OPRM1 TAC1
3	neuronal cell body	GO:0043025	9.63	CCK OPRK1 PDYN PNOC TAC1 TRPV1
4	perikaryon	GO:0043204	9.56	CCK NPFF OPRK1 OPRM1
5	terminal bouton	GO:0043195	9.5	AP2M1 CCK OXT
6	clathrin adaptor complex	GO:0030131	9.37	AP1M2 AP2M1
7	axon terminus	GO:0043679	9.26	NPFF OPRK1 PDYN PNOC
8	dendrite	GO:0030425	9.23	CCK HTR7 NPFF OPRK1 OPRM1 PDYN
9	plasma membrane	GO:0005886	10.18	AP2M1 CNR1 HTR7 OPRK1 OPRL1 OPRM1

Biological processes related to Agnosia according to GeneCards Suite gene sharing:

(show all 34)

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of apoptotic process	GO:0043065	9.96	CCK CNR1 PSENEN TRPV1
2	positive regulation of cytosolic calcium ion concentration	GO:0007204	9.91	NPFF OPRL1 OXT TAC1 TRPV1
3	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	GO:0007187	9.85	CNR1 HTR7 OPRK1 OPRL1 OPRM1
4	response to morphine	GO:0043278	9.83	CNR1 NPFF OPRK1 OPRM1 TAC1
5	response to ethanol	GO:0045471	9.82	CNR1 OPRK1 OPRM1
6	excitatory postsynaptic potential	GO:0060079	9.8	NPFF OPRM1 TRPV1
7	response to cocaine	GO:0042220	9.78	CNR1 OPRK1 OPRM1 OXT
8	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	GO:0007193	9.77	OPRK1 OPRL1 OPRM1
9	eating behavior	GO:0042755	9.77	CCK OPRK1 OPRL1 OPRM1 OXT
10	negative regulation of blood pressure	GO:0045776	9.76	CNR1 OPRL1 OXT
11	sensory perception of pain	GO:0019233	9.73	CNR1 OPRK1 OPRL1 OPRM1 TAC1 TRPV1
12	positive regulation of blood pressure	GO:0045777	9.71	CNR1 NPFF OXT
13	estrous cycle	GO:0044849	9.7	OPRK1 OPRL1 OPRM1
14	opioid receptor signaling pathway	GO:0038003	9.67	OPRK1 OPRL1 OPRM1
15	maternal process involved in female pregnancy	GO:0060135	9.66	CNR1 NPFF
16	response to food	GO:0032094	9.65	OPRM1 OXT
17	response to pain	GO:0048265	9.65	TAC1 TRPV1
18	positive regulation of ossification	GO:0045778	9.64	OXT TAC1
19	positive regulation of renal sodium excretion	GO:0035815	9.64	OXT TAC1
20	maternal behavior	GO:0042711	9.63	OPRK1 OXT
21	negative regulation of heart rate	GO:0010459	9.63	NPFF TAC1
22	negative regulation of appetite	GO:0032099	9.62	CCK NPFF
23	behavior	GO:0007610	9.61	OPRK1 OPRL1
24	acute inflammatory response to antigenic stimulus	GO:0002438	9.61	NPFF OPRM1
25	negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway	GO:0106072	9.59	OPRL1 OPRM1
26	adenylate cyclase-inhibiting opioid receptor signaling pathway	GO:0031635	9.57	OPRK1 OPRM1
27	positive regulation of gastric acid secretion	GO:0060454	9.56	OPRL1 TRPV1
28	sensory perception	GO:0007600	9.55	OPRK1 OPRL1 OPRM1 PDYN PNOC
29	regulation of sensory perception of pain	GO:0051930	9.43	CCK NPFF OPRK1 OPRL1 OPRM1 OXT
30	neuropeptide signaling pathway	GO:0007218	9.23	NPFF OPRK1 OPRL1 OPRM1 PDYN PNOC
31	signal transduction	GO:0007165	10.27	CCK CNR1 HTR7 OPRK1 OPRL1 OPRM1
32	G-protein coupled receptor signaling pathway	GO:0007186	10.1	CCK CNR1 HTR7 NPFF OPRK1 OPRL1
33	regulation of signaling receptor activity	GO:0010469	10.02	CCK NPFF OXT PDYN PNOC POMC
34	chemical synaptic transmission	GO:0007268	10.01	HTR7 NPFF OPRK1 OPRL1 OPRM1 PDYN

Molecular functions related to Agnosia according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	hormone activity	GO:0005179	9.58	CCK OXT POMC
2	peptide binding	GO:0042277	9.54	OPRK1 OPRL1 OPRM1
3	neuropeptide binding	GO:0042923	9.33	OPRK1 OPRL1 OPRM1
4	opioid peptide activity	GO:0001515	9.32	PDYN PNOC
5	opioid receptor binding	GO:0031628	9.26	PDYN PNOC
6	opioid receptor activity	GO:0004985	9.13	OPRK1 OPRL1 OPRM1
7	neuropeptide hormone activity	GO:0005184	9.1	CCK NPFF OXT PDYN PNOC POMC

Sources

Sources for Agnosia

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia