ADC
MCID: ADS004
MIFTS: 39

Aids Dementia Complex (ADC)

Categories: Mental diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Aids Dementia Complex

MalaCards integrated aliases for Aids Dementia Complex:

Name: Aids Dementia Complex 20 54 70
Aids Related Cognitive Impairment 20
Adc 20

Classifications:



External Ids:

UMLS 70 C0001849

Summaries for Aids Dementia Complex

MalaCards based summary : Aids Dementia Complex, also known as aids related cognitive impairment, is related to acquired immunodeficiency syndrome and dementia. An important gene associated with Aids Dementia Complex is ITIH4 (Inter-Alpha-Trypsin Inhibitor Heavy Chain 4), and among its related pathways/superpathways are Akt Signaling and PAK Pathway. The drugs Epinephrine and Formaldehyde have been mentioned in the context of this disorder. Affiliated tissues include monocytes, brain and bone, and related phenotypes are cellular and liver/biliary system

Wikipedia : 73 HIV-associated neurocognitive disorders (HAND) are neurological disorders associated with HIV infection... more...

Related Diseases for Aids Dementia Complex

Diseases related to Aids Dementia Complex via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 340)
# Related Disease Score Top Affiliating Genes
1 acquired immunodeficiency syndrome 30.8 TNF ITIH4 B2M
2 dementia 30.5 TNF ITIH4 CXCR4
3 cytomegalovirus retinitis 30.0 TNF CXCL12
4 encephalitis 30.0 TNF ITIH4 CXCR4
5 central nervous system lymphoma 29.9 CXCR4 CXCL12
6 lymphoma, non-hodgkin, familial 29.6 CXCR4 CXCL12 B2M
7 diffuse large b-cell lymphoma 29.5 TNF CXCR4 B2M
8 stroke, ischemic 29.4 TNF CXCR4 CXCL12
9 myeloma, multiple 29.4 TNF CXCR4 CXCL12 B2M
10 peripheral nervous system disease 29.2 TNF CXCR4 CXCL12 B2M
11 human immunodeficiency virus type 1 29.2 TNF ITIH4 CXCR4 CXCL12 CCR3 B2M
12 asthma 28.5 TNF CXCR4 CXCL12 CCR3
13 human immunodeficiency virus infectious disease 28.5 TNF ITIH4 CXCR4 CXCL12 CCR3 B2M
14 immune deficiency disease 28.3 TNF ITIH4 CXCR4 CXCL12 CCR3 B2M
15 aids - neurological complications 11.1
16 adenosquamous lung carcinoma 11.1
17 leukoencephalopathy with ataxia 10.9
18 prostate cancer 10.5
19 glioblastoma 10.4
20 encephalopathy 10.4
21 dementia - subcortical 10.3
22 rectum cancer 10.3
23 cerebral atrophy 10.3
24 meningioma, familial 10.3
25 intracranial meningioma 10.3
26 secretory meningioma 10.3
27 lymphoplasmacyte-rich meningioma 10.3
28 cervical cancer 10.2
29 glioma 10.2
30 glial tumor 10.2
31 endometrial cancer 10.2
32 kaposi sarcoma 10.2
33 toxoplasmosis 10.2
34 hemangioma 10.2
35 high grade glioma 10.2
36 neutropenia 10.2
37 squamous cell carcinoma 10.2
38 pancreatic adenocarcinoma 10.2
39 sarcoma 10.2
40 spindle cell sarcoma 10.2
41 small cell cancer of the lung 10.1
42 post-transplant lymphoproliferative disease 10.1 TNF B2M
43 pyelitis 10.1 TNF B2M
44 pleural tuberculosis 10.1 TNF B2M
45 acute kidney tubular necrosis 10.1 TNF B2M
46 breast cancer 10.1
47 lymphoma, hodgkin, classic 10.1
48 pancreatic ductal adenocarcinoma 10.1
49 syphilis 10.1 TNF B2M
50 bursitis 10.1 TNF CXCL12

Graphical network of the top 20 diseases related to Aids Dementia Complex:



Diseases related to Aids Dementia Complex

Symptoms & Phenotypes for Aids Dementia Complex

MGI Mouse Phenotypes related to Aids Dementia Complex:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.73 B2M CCR3 CXCL12 CXCR4 ITIH4 TNF
2 liver/biliary system MP:0005370 9.46 B2M CXCL12 ITIH4 TNF
3 neoplasm MP:0002006 9.26 B2M CXCR4 ITIH4 TNF
4 reproductive system MP:0005389 9.02 B2M CXCL12 CXCR4 ITIH4 TNF

Drugs & Therapeutics for Aids Dementia Complex

Drugs for Aids Dementia Complex (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 82)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
2
Formaldehyde Approved, Vet_approved Phase 4 50-00-0 712
3
Racepinephrine Approved Phase 4 329-65-7 838
4
Atorvastatin Approved Phase 4 134523-00-5 60823
5
Ritonavir Approved, Investigational Phase 4 155213-67-5 392622
6
Cobicistat Approved Phase 4 1004316-88-4
7
Darunavir Approved Phase 4 635728-49-3, 206361-99-1 213039
8 Epinephryl borate Phase 4
9 Vasoconstrictor Agents Phase 4
10 Antimetabolites Phase 4
11 Anticholesteremic Agents Phase 4
12 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
13 Hypolipidemic Agents Phase 4
14 Lipid Regulating Agents Phase 4
15 Anti-Retroviral Agents Phase 4
16 Cytochrome P-450 CYP3A Inhibitors Phase 4
17 Antiviral Agents Phase 4
18 Anti-HIV Agents Phase 4
19 Anti-Infective Agents Phase 4
20 HIV Protease Inhibitors Phase 4
21 Cytochrome P-450 Enzyme Inhibitors Phase 4
22
protease inhibitors Phase 4
23
Methylphenidate Approved, Investigational Phase 3 113-45-1 4158
24
Maraviroc Approved, Investigational Phase 2, Phase 3 376348-65-1 3002977
25
Abacavir Approved, Investigational Phase 3 136470-78-5 65140 441300
26
Zidovudine Approved Phase 3 30516-87-1 35370
27
Stavudine Approved, Investigational Phase 3 3056-17-5 18283
28 Central Nervous System Stimulants Phase 3
29 Dopamine Uptake Inhibitors Phase 3
30 Reverse Transcriptase Inhibitors Phase 3
31
Iron Approved Phase 2 7439-89-6 23925 29936
32
Dopamine Approved Phase 2 51-61-6, 62-31-7 681
33
Memantine Approved, Investigational Phase 2 19982-08-2 4054
34
Didanosine Approved Phase 2 69655-05-6 50599
35
tannic acid Approved Phase 2 1401-55-4
36
Lactulose Approved Phase 2 4618-18-2 11333
37
Galantamine Approved Phase 2 357-70-0 9651
38
Nicotine Approved Phase 2 54-11-5 942 89594
39
Benzocaine Approved, Investigational Phase 2 1994-09-7, 94-09-7 2337
40 Neurotransmitter Agents Phase 2
41 Hematinics Phase 2
42 Ferrosoferric Oxide Phase 2
43 Parenteral Nutrition Solutions Phase 2
44 Dopamine Agents Phase 2
45 TAK-652 Phase 2
46 Excitatory Amino Acid Antagonists Phase 2
47 Antiparkinson Agents Phase 2
48 Cholinesterase Inhibitors Phase 2
49 Cholinergic Agents Phase 2
50 Nootropic Agents Phase 2

Interventional clinical trials:

(show all 32)
# Name Status NCT ID Phase Drugs
1 Study of Nasal Brushing Collected OLFActory MUcosa Samples in the Diagnosis of Human Encephalopathies Unknown status NCT02951559 Phase 4
2 Pilot Study to Evaluate Effects of Atorvastatin on Monocyte Activation in HAART-treated HIV Infected Individuals Completed NCT01263938 Phase 4 Atorvastatin
3 Statin Modulation of Monocyte/Macrophage Activation for HAND Treatment Completed NCT01600170 Phase 4 Atorvastatin (generic Lipitor);placebo
4 Effect of Cobicistat Versus Ritonavir Boosting on the Brain Permeation of Darunavir in HIV-infected Individuals Terminated NCT02503462 Phase 4 Darunavir;ritonavir;cobicistat
5 Phase III, Placebo-Controlled, Double-Blind Crossover Study of Slow-Release Methylphenidate (Concerta ™) for Treatment of HIV Associated Neurocognitive Disorder Unknown status NCT01599975 Phase 3 Long acting methylphenidate;Long acting methylphenidate;Matched placebo
6 Maraviroc and NeuroAIDS Pathogenesis Unknown status NCT02159027 Phase 2, Phase 3 Maraviroc;Placebo
7 A Phase III, Randomized, Double-Blind, Multicentre Study to Evaluate the Safety and Efficacy of 1592U89 in Patients With AIDS Dementia Complex Completed NCT00002163 Phase 3 Abacavir sulfate
8 An Open Trial of Zidovudine (AZT) Treatment of the AIDS Dementia Complex in Patients With AIDS or Low CD4+ Lymphocyte Counts Completed NCT00000709 Phase 3 Zidovudine
9 A Multicenter Placebo-Controlled Double-Blind Trial to Evaluate Azidothymidine (AZT) Treatment of the AIDS Dementia Complex and Central Nervous System (CNS) Human Immunodeficiency Virus (HIV) Infection Completed NCT00000702 Phase 3 Zidovudine
10 A Pilot Open Label, Multicenter Study to Evaluate the Role of Stavudine (d4T) in the Treatment of AIDS Dementia Complex Completed NCT00002246 Phase 3 Stavudine
11 Ferumoxytol-enhanced Imaging and Quantitative Susceptibility Mapping in neuroAIDS Completed NCT02678767 Phase 2 Ferumoxytol
12 H020: Single-Arm Open Label, Pilot Study of CCR5/CCR2 Inhibitor Cenicriviroc (CVC) for HIV Associated Neurocognitive Disorder (HAND) Completed NCT02128828 Phase 2 cenicriviroc
13 A Phase II, Randomized, Double Blind, Placebo-Controlled Trial of Memantine for AIDS Dementia Complex (ADC) as Concurrent Treatment With Antiretroviral Therapy Completed NCT00000867 Phase 2 Memantine
14 Comparison of 2',3'-Dideoxyinosine (Didanosine, ddI) and Zidovudine in Therapy of Patients With the AIDS Dementia Complex Completed NCT00000657 Phase 2 Zidovudine;Didanosine
15 Targeting the Cholinergic Pathway in HIV-associated Inflammation and Cognitive Dysfunction Recruiting NCT03384784 Phase 2 Galantamine;Placebo
16 Clinical Trial of Intranasal Insulin for the Treatment of HIV-associated Neurocognitive Disorder (HAND) Terminated NCT03081117 Phase 1, Phase 2 Insulin, intranasal;Placebo, intranasal
17 Neuroimaging Correlates of Monocyte/Macrophage Infiltration in HIV-infected Individuals: A Cross-sectional Pilot Study Using IV Ferumoxytol Completed NCT01665846 Phase 1 Ferumoxytol
18 Parallel Group, Placebo-Controlled, Tolerability, Safety, and Efficacy Study of OPC-14117 in HIV Dementia Completed NCT00002148 Phase 1 OPC 14117
19 Randomized, Double-Blind, Placebo-Controlled Trial of Nimodipine for the Neurological Manifestations of HIV-1 Completed NCT00000738 Phase 1 Nimodipine;Zidovudine
20 Multiple Ascending Dose Pharmacokinetics of CPI-1189 (LU 02-584) in Fasted, HIV Infected, Male Volunteers on Combined Reverse Transcriptase and Protease Inhibitor Therapy Completed NCT00002209 Phase 1 CPI-1189
21 A Prospective, Epidemiologic and Multicentre Trial to Determine the Cardiovascular Risk, New Cardiovascular Events and the Cardiovascular Diseases in HIV-infected Patients: 12,5 Year Follow up Completed NCT04156048
22 The CNS HAND Study: The Prevalence of Neurocognitive Disorder in a Primary Care-based HIV Cohort Compared to a HIV-negative Control Cohort Completed NCT01434563
23 A Prospective, Epidemiologic and Multicentre Trial to Determine the Cardiovascular Risk, New Cardiovascular Events and the Cardiovascular Diseases in HIV-infected Patients: 10 Year Follow-up Completed NCT02291081
24 A Pilot Study To Evaluate the Effect of Retrovir (Zidovudine: AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Associated Dementia and Neuromuscular Diseases Completed NCT00002044 Zidovudine
25 Cholinergic Correlates of Impaired Cognitive Ability in HIV-Associated Neurocognitive Disorders Completed NCT03244488 Scopolamine Injectable Product;Mecamylamine Pill
26 Individualized-Targeted Cognitive Training in Older Adults With HAND Completed NCT03122288
27 Evaluation of the Role of Optical Coherence Tomography (OCT) in the Detection of HIV-associated Neurocognitive Disorder Recruiting NCT02431091
28 A Prospective, Epidemiologic and Multicentre Trial to Determine the Cardiovascular Risk, New Cardiovascular Events and the Cardiovascular Diseases in HIV-infected Patients: 15 Year Follow up Recruiting NCT04330287
29 PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects Enrolling by invitation NCT03581305 18F-FDOPA;11C-DASB
30 Exploring Racial Disparities in Sleep Health and Neurocognitive Function in Older Adults With HIV Not yet recruiting NCT04015830
31 Inflammation and Function of P-gp in HIV Infection of Brain Terminated NCT01547754
32 PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using (11C)PBR28 in HIV-Seropositive Patients With (MCMD) Terminated NCT00459693 [11C]PBR28

Search NIH Clinical Center for Aids Dementia Complex

Genetic Tests for Aids Dementia Complex

Anatomical Context for Aids Dementia Complex

MalaCards organs/tissues related to Aids Dementia Complex:

40
Monocytes, Brain, Bone, Kidney, Lung, Liver, Breast

Publications for Aids Dementia Complex

Articles related to Aids Dementia Complex:

(show top 50) (show all 584)
# Title Authors PMID Year
1
In vivo expression of proinflammatory cytokines in HIV encephalitis: an analysis of 11 autopsy cases. 54 61
19170891 2009
2
[Analysis of genetic diversity and biological functional site of HIV-1 gp120 from a patient with AIDS dementia complex]. 54 61
19634757 2009
3
CCL3L1 prevents gp120-induced neuron death via the CREB cell signaling pathway. 54 61
19100722 2009
4
Undetectable cerebrospinal fluid HIV RNA and beta-2 microglobulin do not indicate inactive AIDS dementia complex in highly active antiretroviral therapy-treated patients. 61 54
16010165 2005
5
Expression of the urokinase plasminogen activator and its receptor in HIV-1-associated central nervous system disease. 61 54
15579290 2004
6
SDF-1alpha is expressed in astrocytes and neurons in the AIDS dementia complex: an in vivo and in vitro study. 61 54
12834106 2003
7
Tumor necrosis factor-alpha induces neuronal death by silencing survival signals generated by the type I insulin-like growth factor receptor. 54 61
11268346 2000
8
Potential role of CCR5 polymorphism in the development of AIDS dementia complex. 61 54
10575135 1999
9
Overexpression of nerve growth factor and basic fibroblast growth factor in AIDS dementia complex. 54 61
10408969 1999
10
Nitric oxide synthase expression and apoptotic cell death in brains of AIDS and AIDS dementia patients. 61 54
10199221 1999
11
Human immunodeficiency virus type 1 envelope glycoprotein gp120 induces tumor necrosis factor-alpha in astrocytes. 54 61
16873189 1999
12
Unique HIV type 1 V3 region sequences derived from six different regions of brain: region-specific evolution within host-determined quasispecies. 54 61
9453248 1998
13
Tumor necrosis factor-alpha, microglia and astrocytes in AIDS dementia complex. 54 61
9144590 1997
14
Pathogenetic role of phagocytic abnormalities in human virus immunodeficiency infection: possible therapeutical approaches. A review. 54 61
9130002 1997
15
Monokine products as predictors of AIDS dementia. 61 54
8931783 1996
16
Predictive markers of AIDS dementia complex: CD4 cell count and cerebrospinal fluid concentrations of beta 2-microglobulin and neopterin. 54 61
8699058 1996
17
HIV glycoprotein 120 enhances intercellular adhesion molecule-1 gene expression in glial cells. Involvement of Janus kinase/signal transducer and activator of transcription and protein kinase C signaling pathways. 54 61
8558011 1996
18
TNF-alpha- and IFN-gamma-mediated signal transduction pathways: effects on glial cell gene expression and function. 61 54
8529837 1995
19
Distinct expressions of three cytokines by IL-1-stimulated astrocytes in vitro and in AIDS brain. 61 54
8903854 1995
20
Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA. 54 61
7739519 1995
21
Myelin degrading activity in the CSF of HIV-1-infected patients with neurological diseases. 61 54
7535576 1994
22
Low levels of specific T cell activation marker CD27 accompanied by elevated levels of markers for non-specific immune activation in the cerebrospinal fluid of patients with AIDS dementia complex. 61 54
8227320 1993
23
Cerebrospinal fluid myelin basic protein in AIDS dementia complex: relationship to disease progression and zidovudine treatment. 61 54
1281644 1992
24
Cerebrospinal fluid cytokines in AIDS dementia complex. 61 54
1403021 1992
25
Cerebrospinal fluid beta-2-microglobulin in multiple sclerosis and AIDS dementia complex. 61 54
1355285 1992
26
Cerebrospinal fluid beta 2-microglobulin in patients with AIDS dementia complex: an expanded series including response to zidovudine treatment. 54 61
1616651 1992
27
Tumour necrosis factor (TNF-alpha) and neurological disorders in HIV infection. 61 54
1564486 1992
28
Cerebrospinal fluid myelin basic protein as predictive marker of demyelination in AIDS dementia complex. 54 61
1370671 1992
29
Detection of cerebrospinal fluid antibodies against myelin basic protein in patients with AIDS dementia complex. 54 61
1720316 1991
30
HIV-infection and in vivo lipopolysaccharide-induced release of cytokines. An amplified mechanism of damage to the host. 54 61
1891985 1991
31
Coronaviruses: a challenge of today and a call for extended human postmortem brain analyses. 61
32725545 2020
32
Neurological disorders in HIV in Africa: a review. 61
31656479 2019
33
Progressive brain atrophy in chronically infected and treated HIV+ individuals. 61
30767174 2019
34
The involvement of the substance P/neurokinin 1 receptor system in viral infection: focus on the gp120 fusion protein and homologous dipeptide domains. 61
31507190 2019
35
HIV-1-Associated Neurocognitive Disorders: Is HLA-C Binding Stability to β2-Microglobulin a Missing Piece of the Pathogenetic Puzzle? 61
30298049 2018
36
Overview of the role of vitamins and minerals on the kynurenine pathway in health and disease. 61
27010891 2016
37
Development and in vivo evaluation of an implantable nano-enabled multipolymeric scaffold for the management of AIDS dementia complex (ADC). 61
26456249 2015
38
[HIV- DEMENTIA. A REVIEW THIRTY FIVE YEARS AFTER (1981-2015)]. 61
26650556 2015
39
Neurotoxic effects of AZT on developing and adult neurogenesis. 61
25852464 2015
40
Treatment of HIV in the CNS: effects of antiretroviral therapy and the promise of non-antiretroviral therapeutics. 61
25063356 2014
41
Effects of HIV-1 tat on secretion of TNF-α and IL-1β by U87 cells in AIDS patients with or without AIDS dementia complex. 61
24625401 2014
42
The D-amino acid peptide D3 reduces amyloid fibril boosted HIV-1 infectivity. 61
24422713 2014
43
Proton 1H- and Phosphorus 31P-MR spectroscopy (MRS) in asymptomatic HIV-positive patients. 61
25394084 2014
44
HIV, dementia and antiretroviral drugs: 30 years of an epidemic. 61
23378642 2013
45
FDG-PET imaging in HIV infection and tuberculosis. 61
23905617 2013
46
Epidemiology and trend of neurological diseases associated to HIV/AIDS. Experience of Mexican patients 1995-2009. 61
23369401 2013
47
CNS toxoplasmosis induced hydrocephalus revisited and a brief review of AIDS dementia complex. 61
23749026 2013
48
[Analysis of genetic diversity of HIV-1 nef genes from a patient with AIDS dementia complex]. 61
23855121 2013
49
Design and pharmaceutical evaluation of a nano-enabled crosslinked multipolymeric scaffold for prolonged intracranial release of Zidovudine. 61
24021294 2013
50
Disrupted cerebral metabolite levels and lower nadir CD4 + counts are linked to brain volume deficits in 210 HIV-infected patients on stable treatment. 61
24179857 2013

Variations for Aids Dementia Complex

Expression for Aids Dementia Complex

Search GEO for disease gene expression data for Aids Dementia Complex.

Pathways for Aids Dementia Complex

Pathways related to Aids Dementia Complex according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.96 TNF CXCR4 CXCL12 CCR3
2
Show member pathways
12.8 TNF CXCR4 CXCL12 CCR3
3
Show member pathways
12.36 TNF CXCR4 CXCL12 B2M
4 11.97 TNF CXCR4 CXCL12 B2M
5
Show member pathways
11.82 TNF CXCR4 CXCL12 CCR3 B2M
6
Show member pathways
11.59 TNF CXCR4 CXCL12 CCR3
7 11.4 CXCR4 CXCL12
8 11.31 CXCR4 CXCL12
9 11.28 TNF CCR3
10
Show member pathways
11.24 TNF B2M
11 11.09 CXCR4 CXCL12
12 10.86 CXCR4 CXCL12
13 10.21 TNF CXCL12

GO Terms for Aids Dementia Complex

Cellular components related to Aids Dementia Complex according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.43 TNF ITIH4 CXCR4 CXCL12 CCR3 B2M
2 external side of plasma membrane GO:0009897 9.02 TNF CXCR4 CXCL12 CCR3 B2M

Biological processes related to Aids Dementia Complex according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.7 TNF CXCR4 CCR3
2 chemotaxis GO:0006935 9.61 CXCR4 CXCL12 CCR3
3 calcium-mediated signaling GO:0019722 9.56 CXCR4 CCR3
4 chemokine-mediated signaling pathway GO:0070098 9.55 CXCL12 CCR3
5 positive regulation of endothelial cell proliferation GO:0001938 9.54 CXCL12 CCR3
6 positive regulation of cell adhesion GO:0045785 9.51 TNF CXCL12
7 response to virus GO:0009615 9.5 TNF CXCR4 CXCL12
8 regulation of calcium ion transport GO:0051924 9.49 CXCR4 CXCL12
9 negative regulation of neurogenesis GO:0050768 9.48 TNF B2M
10 detection of temperature stimulus involved in sensory perception of pain GO:0050965 9.46 CXCR4 CXCL12
11 detection of mechanical stimulus involved in sensory perception of pain GO:0050966 9.4 CXCR4 CXCL12
12 cellular response to nicotine GO:0071316 9.37 TNF B2M
13 cell chemotaxis GO:0060326 9.33 CXCR4 CXCL12 CCR3
14 telencephalon cell migration GO:0022029 9.26 CXCR4 CXCL12
15 immune response GO:0006955 9.02 TNF CXCR4 CXCL12 CCR3 B2M
16 response to ultrasound GO:1990478 8.96 CXCR4 CXCL12

Molecular functions related to Aids Dementia Complex according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 C-C chemokine binding GO:0019957 9.16 CXCR4 CCR3
2 C-C chemokine receptor activity GO:0016493 8.96 CXCR4 CCR3
3 chemokine receptor activity GO:0004950 8.62 CXCR4 CCR3

Sources for Aids Dementia Complex

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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