MCID: ALC012
MIFTS: 33

Alcoholic Gastritis

Categories: Gastrointestinal diseases

Aliases & Classifications for Alcoholic Gastritis

MalaCards integrated aliases for Alcoholic Gastritis:

Name: Alcoholic Gastritis 12 15 74
Alcoholic Gastritis, Without Mention of Hemorrhage 12
Alcoholic Gastritis, with Hemorrhage 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8680
ICD9CM 36 535.3
NCIt 51 C26977
SNOMED-CT 69 2043009
ICD10 34 K29.2
UMLS 74 C0156076

Summaries for Alcoholic Gastritis

MalaCards based summary : Alcoholic Gastritis, also known as alcoholic gastritis, without mention of hemorrhage, is related to gastritis and familial cold autoinflammatory syndrome 1, and has symptoms including dyspepsia An important gene associated with Alcoholic Gastritis is PLA2G5 (Phospholipase A2 Group V), and among its related pathways/superpathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Affiliated tissues include bone, and related phenotypes are Increased viability and cardiovascular system

Related Diseases for Alcoholic Gastritis

Diseases related to Alcoholic Gastritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
# Related Disease Score Top Affiliating Genes
1 gastritis 30.3 IL1B PTGS2
2 familial cold autoinflammatory syndrome 1 10.1 CASP1 IL1B
3 chronic recurrent multifocal osteomyelitis 10.1 CASP1 IL1B
4 muckle-wells syndrome 10.1 CASP1 IL1B
5 cinca syndrome 10.1 CASP1 IL1B
6 legionellosis 10.0 CASP1 IL1B
7 typhoid fever 10.0 CASP1 IL1B
8 autoinflammation with arthritis and dyskeratosis 10.0 CASP1 IL18
9 familial mediterranean fever 10.0 CASP1 IL1B
10 schnitzler syndrome 10.0 IL18 IL1B
11 uremic pruritus 10.0 IL18 IL1B
12 stachybotrys chartarum 10.0 IL18 IL1B
13 cysticercosis 10.0 IL18 IL1B
14 chlamydia 10.0 CASP1 IL1B
15 adult-onset still's disease 10.0 IL18 IL1B
16 extrinsic allergic alveolitis 10.0 IL18 IL1B
17 lymphadenitis 10.0 IL18 IL1B
18 juvenile rheumatoid arthritis 9.9 IL18 IL1B
19 synovitis 9.9 IL18 IL1B
20 endometrial disease 9.9 IL1B PTGS2
21 pharyngitis 9.9 IL1B PTGS2
22 gastric ulcer 9.9 IL1B PTGS2
23 peptic ulcer disease 9.9 IL1B PTGS2
24 esophagitis 9.9 IL1B PTGS2
25 bone inflammation disease 9.8 IL1B PTGS2
26 stomach disease 9.8 IL1B PTGS2
27 sarcoidosis 1 9.8 IL18 IL1B
28 gastroesophageal reflux 9.8 IL1B PTGS2
29 intestinal disease 9.8 IL1B PTGS2
30 familial cold autoinflammatory syndrome 9.7 CASP1 IL18 IL1B
31 salmonellosis 9.7 CASP1 IL18 IL1B
32 periodontal disease 9.7 IL18 IL1B
33 bacterial infectious disease 9.7 CASP1 IL18 IL1B
34 endometriosis 9.7 IL1B PTGS2
35 proteasome-associated autoinflammatory syndrome 1 9.6 IL18 IL1B PTGS2
36 rheumatic disease 9.6 IL18 IL1B PTGS2
37 malaria 9.6 CASP1 IL18 IL1B
38 arthritis 9.5 IL18 IL1B PTGS2
39 gastrointestinal system disease 9.5 IL1B PTGS2
40 myocardial infarction 9.5 CASP1 IL1B PTGS2
41 rheumatoid arthritis 9.5 IL18 IL1B PTGS2

Comorbidity relations with Alcoholic Gastritis via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Acute Pancreatitis
Alcohol Abuse Alcoholic Hepatitis
Alcoholic Liver Cirrhosis Deficiency Anemia
Esophagitis

Graphical network of the top 20 diseases related to Alcoholic Gastritis:



Diseases related to Alcoholic Gastritis

Symptoms & Phenotypes for Alcoholic Gastritis

UMLS symptoms related to Alcoholic Gastritis:


dyspepsia

GenomeRNAi Phenotypes related to Alcoholic Gastritis according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased viability GR00386-A-1 9.02 CASP1 IL18 IL1B PLA2G5 PTGS2

MGI Mouse Phenotypes related to Alcoholic Gastritis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.72 CASP1 IL18 IL1B PLA2G5 PTGS2
2 hematopoietic system MP:0005397 9.65 CASP1 IL18 IL1B PLA2G5 PTGS2
3 homeostasis/metabolism MP:0005376 9.55 CASP1 IL18 IL1B PLA2G5 PTGS2
4 immune system MP:0005387 9.35 CASP1 IL18 IL1B PLA2G5 PTGS2
5 integument MP:0010771 8.92 CASP1 IL18 IL1B PTGS2

Drugs & Therapeutics for Alcoholic Gastritis

Search Clinical Trials , NIH Clinical Center for Alcoholic Gastritis

Genetic Tests for Alcoholic Gastritis

Anatomical Context for Alcoholic Gastritis

MalaCards organs/tissues related to Alcoholic Gastritis:

42
Bone

Publications for Alcoholic Gastritis

Articles related to Alcoholic Gastritis:

# Title Authors Year
1
Combined Extracts of Artemisia and Green Tea, Mitigated Alcoholic Gastritis Via Enhanced Heat-shock Protein 27. ( 29566474 )
2018
2
A New Participant in the Pathogenesis of Alcoholic Gastritis: Pyroptosis. ( 30138921 )
2018
3
Reduced Prevalence of Alcoholic Gastritis in Hospitalized Individuals Who Consume Cannabis. ( 30536396 )
2018
4
Chronic alcoholic gastritis. Roles of alcohol and Helicobacter pylori. ( 2012461 )
1991
5
Alcoholic gastritis. ( 7249389 )
1981
6
Alcoholic gastritis at the Kenyatta National Hospital. ( 520236 )
1979
7
Alcoholic gastritis. ( 4739206 )
1973
8
Newer concepts of chronic alcoholic gastritis; gastroscopic studies. ( 13357949 )
1956

Variations for Alcoholic Gastritis

Expression for Alcoholic Gastritis

Search GEO for disease gene expression data for Alcoholic Gastritis.

Pathways for Alcoholic Gastritis

Pathways related to Alcoholic Gastritis according to GeneCards Suite gene sharing:

(show all 32)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.29 CASP1 IL18 IL1B PTGS2
2
Show member pathways
12.98 CASP1 IL18 IL1B PTGS2
3
Show member pathways
12.91 CASP1 IL18 IL1B PLA2G5
4
Show member pathways
12.75 CASP1 IL18 IL1B
5 12.44 CASP1 IL1B PLA2G5
6
Show member pathways
12.43 CASP1 IL18 IL1B
7
Show member pathways
11.92 IL18 IL1B PTGS2
8
Show member pathways
11.89 CASP1 IL1B PTGS2
9
Show member pathways
11.77 IL18 IL1B
10
Show member pathways
11.75 CASP1 IL18 IL1B
11
Show member pathways
11.71 PLA2G5 PTGS2
12 11.71 IL1B PLA2G5 PTGS2
13
Show member pathways
11.69 IL18 IL1B
14 11.67 IL1B PTGS2
15 11.67 IL18 IL1B PTGS2
16 11.63 IL1B PTGS2
17 11.58 IL18 IL1B
18 11.52 IL18 IL1B
19 11.51 CASP1 IL18 IL1B
20 11.49 CASP1 IL1B
21
Show member pathways
11.4 IL1B PTGS2
22 11.4 IL18 IL1B PTGS2
23 11.27 IL18 IL1B
24 11.26 IL18 IL1B
25 11.24 CASP1 IL18 IL1B
26 11.12 IL18 IL1B PTGS2
27 11.1 IL18 IL1B
28 11.03 IL18 IL1B
29 10.94 CASP1 IL18 IL1B
30 10.91 IL18 IL1B
31 10.47 CASP1 IL18 IL1B
32 9.64 CASP1 IL18 IL1B

GO Terms for Alcoholic Gastritis

Biological processes related to Alcoholic Gastritis according to GeneCards Suite gene sharing:

(show all 23)
# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.73 IL18 IL1B PTGS2
2 cellular response to organic cyclic compound GO:0071407 9.6 IL18 IL1B
3 response to cytokine GO:0034097 9.58 PLA2G5 PTGS2
4 positive regulation of smooth muscle cell proliferation GO:0048661 9.58 IL18 PTGS2
5 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.57 IL18 IL1B
6 positive regulation of interferon-gamma production GO:0032729 9.55 IL18 IL1B
7 positive regulation of nitric oxide biosynthetic process GO:0045429 9.54 IL1B PTGS2
8 cellular response to organic substance GO:0071310 9.52 CASP1 IL1B
9 embryo implantation GO:0007566 9.51 IL1B PTGS2
10 lipopolysaccharide-mediated signaling pathway GO:0031663 9.49 IL18 IL1B
11 positive regulation of vascular endothelial growth factor production GO:0010575 9.48 IL1B PTGS2
12 positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032725 9.4 IL18 IL1B
13 interleukin-6 production GO:0032635 9.37 IL18 IL1B
14 positive regulation of neuroinflammatory response GO:0150078 9.32 IL18 IL1B
15 response to estradiol GO:0032355 9.31 PTGS2
16 memory GO:0007613 9.3 PTGS2
17 response to glucocorticoid GO:0051384 9.29 PTGS2
18 positive regulation of fever generation GO:0031622 9.26 IL1B PTGS2
19 response to vitamin D GO:0033280 9.16 PTGS2
20 positive regulation of T-helper 1 cell cytokine production GO:2000556 9.16 IL18 IL1B
21 ovulation GO:0030728 9.13 PTGS2
22 cellular response to mechanical stimulus GO:0071260 9.13 CASP1 IL1B PTGS2
23 cytokine-mediated signaling pathway GO:0019221 8.92 CASP1 IL18 IL1B PTGS2

Sources for Alcoholic Gastritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....