MCID: ALC012
MIFTS: 33

Alcoholic Gastritis

Categories: Gastrointestinal diseases

Aliases & Classifications for Alcoholic Gastritis

MalaCards integrated aliases for Alcoholic Gastritis:

Name: Alcoholic Gastritis 12 15 73
Alcoholic Gastritis, Without Mention of Hemorrhage 12
Alcoholic Gastritis, with Hemorrhage 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8680
ICD10 33 K29.2
ICD9CM 35 535.3
NCIt 50 C26977
SNOMED-CT 68 2043009
UMLS 73 C0156076

Summaries for Alcoholic Gastritis

MalaCards based summary : Alcoholic Gastritis, also known as alcoholic gastritis, without mention of hemorrhage, is related to gastritis and familial cold autoinflammatory syndrome 1, and has symptoms including dyspepsia An important gene associated with Alcoholic Gastritis is PLA2G5 (Phospholipase A2 Group V), and among its related pathways/superpathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Affiliated tissues include bone, and related phenotypes are Increased viability and cardiovascular system

Related Diseases for Alcoholic Gastritis

Diseases related to Alcoholic Gastritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
# Related Disease Score Top Affiliating Genes
1 gastritis 30.3 IL1B PTGS2
2 familial cold autoinflammatory syndrome 1 10.1 CASP1 IL1B
3 chronic recurrent multifocal osteomyelitis 10.1 CASP1 IL1B
4 muckle-wells syndrome 10.0 CASP1 IL1B
5 cinca syndrome 10.0 CASP1 IL1B
6 legionellosis 10.0 CASP1 IL1B
7 typhoid fever 10.0 CASP1 IL1B
8 autoinflammation with arthritis and dyskeratosis 10.0 CASP1 IL18
9 familial mediterranean fever 10.0 CASP1 IL1B
10 schnitzler syndrome 10.0 IL18 IL1B
11 uremic pruritus 10.0 IL18 IL1B
12 stachybotrys chartarum 10.0 IL18 IL1B
13 cysticercosis 10.0 IL18 IL1B
14 chlamydia 10.0 CASP1 IL1B
15 adult-onset still's disease 10.0 IL18 IL1B
16 extrinsic allergic alveolitis 10.0 IL18 IL1B
17 lymphadenitis 10.0 IL18 IL1B
18 juvenile rheumatoid arthritis 10.0 IL18 IL1B
19 synovitis 9.9 IL18 IL1B
20 endometrial disease 9.9 IL1B PTGS2
21 pharyngitis 9.9 IL1B PTGS2
22 viral encephalitis 9.9 IL1B PTGS2
23 gastric ulcer 9.9 IL1B PTGS2
24 peptic ulcer disease 9.9 IL1B PTGS2
25 esophagitis 9.9 IL1B PTGS2
26 bone inflammation disease 9.9 IL1B PTGS2
27 stomach disease 9.9 IL1B PTGS2
28 gastroesophageal reflux 9.9 IL1B PTGS2
29 periodontal disease 9.9 IL18 IL1B
30 intestinal disease 9.9 IL1B PTGS2
31 familial cold autoinflammatory syndrome 9.8 CASP1 IL18 IL1B
32 salmonellosis 9.8 CASP1 IL18 IL1B
33 bacterial infectious disease 9.8 CASP1 IL18 IL1B
34 sarcoidosis 1 9.8 IL18 IL1B
35 endometriosis 9.8 IL1B PTGS2
36 proteasome-associated autoinflammatory syndrome 1 9.7 IL18 IL1B PTGS2
37 rheumatic disease 9.7 IL18 IL1B PTGS2
38 malaria 9.7 CASP1 IL18 IL1B
39 arthritis 9.7 IL18 IL1B PTGS2
40 gastrointestinal system disease 9.7 IL1B PTGS2
41 myocardial infarction 9.7 CASP1 IL1B PTGS2
42 rheumatoid arthritis 9.6 IL18 IL1B PTGS2
43 inflammatory bowel disease 9.5 CASP1 IL18 IL1B PTGS2

Comorbidity relations with Alcoholic Gastritis via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Acute Pancreatitis
Alcohol Abuse Alcoholic Hepatitis
Alcoholic Liver Cirrhosis Deficiency Anemia
Esophagitis

Graphical network of the top 20 diseases related to Alcoholic Gastritis:



Diseases related to Alcoholic Gastritis

Symptoms & Phenotypes for Alcoholic Gastritis

UMLS symptoms related to Alcoholic Gastritis:


dyspepsia

GenomeRNAi Phenotypes related to Alcoholic Gastritis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased viability GR00386-A-1 9.02 CASP1 IL18 IL1B PLA2G5 PTGS2

MGI Mouse Phenotypes related to Alcoholic Gastritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.72 CASP1 IL18 IL1B PLA2G5 PTGS2
2 hematopoietic system MP:0005397 9.65 CASP1 IL18 IL1B PLA2G5 PTGS2
3 homeostasis/metabolism MP:0005376 9.55 CASP1 IL18 IL1B PLA2G5 PTGS2
4 immune system MP:0005387 9.35 CASP1 IL18 IL1B PLA2G5 PTGS2
5 integument MP:0010771 8.92 CASP1 IL18 IL1B PTGS2

Drugs & Therapeutics for Alcoholic Gastritis

Search Clinical Trials , NIH Clinical Center for Alcoholic Gastritis

Genetic Tests for Alcoholic Gastritis

Anatomical Context for Alcoholic Gastritis

MalaCards organs/tissues related to Alcoholic Gastritis:

41
Bone

Publications for Alcoholic Gastritis

Articles related to Alcoholic Gastritis:

# Title Authors Year
1
Combined Extracts of <i>Artemisia</i> and Green Tea, Mitigated Alcoholic Gastritis Via Enhanced Heat-shock Protein 27. ( 29566474 )
2018
2
A New Participant in the Pathogenesis of Alcoholic Gastritis: Pyroptosis. ( 30138921 )
2018
3
Reduced prevalence of alcoholic gastritis in hospitalized individuals who consume cannabis. ( 30536396 )
2018
4
Chronic alcoholic gastritis. Roles of alcohol and Helicobacter pylori. ( 2012461 )
1991
5
Alcoholic gastritis. ( 7249389 )
1981
6
Alcoholic gastritis at the Kenyatta National Hospital. ( 520236 )
1979
7
Alcoholic gastritis. ( 4739206 )
1973
8
Newer concepts of chronic alcoholic gastritis; gastroscopic studies. ( 13357949 )
1956

Variations for Alcoholic Gastritis

Expression for Alcoholic Gastritis

Search GEO for disease gene expression data for Alcoholic Gastritis.

Pathways for Alcoholic Gastritis

Pathways related to Alcoholic Gastritis according to GeneCards Suite gene sharing:

(show all 33)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.3 CASP1 IL18 IL1B PTGS2
2
Show member pathways
12.98 CASP1 IL18 IL1B PTGS2
3
Show member pathways
12.91 CASP1 IL18 IL1B PLA2G5
4
Show member pathways
12.67 CASP1 IL18 IL1B
5
Show member pathways
12.48 CASP1 IL18 IL1B
6 12.44 CASP1 IL1B PLA2G5
7
Show member pathways
12.43 CASP1 IL18 IL1B
8
Show member pathways
11.92 IL18 IL1B PTGS2
9
Show member pathways
11.89 CASP1 IL1B PTGS2
10
Show member pathways
11.77 IL18 IL1B
11
Show member pathways
11.75 CASP1 IL18 IL1B
12
Show member pathways
11.72 PLA2G5 PTGS2
13 11.71 IL1B PLA2G5 PTGS2
14
Show member pathways
11.7 IL18 IL1B
15 11.68 IL1B PTGS2
16 11.67 IL18 IL1B PTGS2
17 11.61 IL1B PTGS2
18 11.58 IL18 IL1B
19 11.53 IL18 IL1B
20 11.51 CASP1 IL18 IL1B
21 11.5 CASP1 IL1B
22
Show member pathways
11.4 IL1B PTGS2
23 11.4 IL18 IL1B PTGS2
24 11.27 IL18 IL1B
25 11.26 IL18 IL1B
26 11.24 CASP1 IL18 IL1B
27 11.12 IL18 IL1B PTGS2
28 11.08 IL18 IL1B
29 11.03 IL18 IL1B
30 10.94 CASP1 IL18 IL1B
31 10.91 IL18 IL1B
32 10.47 CASP1 IL18 IL1B
33 9.64 CASP1 IL18 IL1B

GO Terms for Alcoholic Gastritis

Biological processes related to Alcoholic Gastritis according to GeneCards Suite gene sharing:

(show all 23)
# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.73 IL18 IL1B PTGS2
2 response to estradiol GO:0032355 9.61 IL1B PTGS2
3 memory GO:0007613 9.61 IL1B PTGS2
4 cellular response to organic cyclic compound GO:0071407 9.6 IL18 IL1B
5 response to glucocorticoid GO:0051384 9.59 IL1B PTGS2
6 response to cytokine GO:0034097 9.58 PLA2G5 PTGS2
7 positive regulation of smooth muscle cell proliferation GO:0048661 9.58 IL18 PTGS2
8 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.57 IL18 IL1B
9 positive regulation of interferon-gamma production GO:0032729 9.55 IL18 IL1B
10 positive regulation of nitric oxide biosynthetic process GO:0045429 9.54 IL1B PTGS2
11 cellular response to organic substance GO:0071310 9.52 CASP1 IL1B
12 embryo implantation GO:0007566 9.51 IL1B PTGS2
13 lipopolysaccharide-mediated signaling pathway GO:0031663 9.49 IL18 IL1B
14 positive regulation of vascular endothelial growth factor production GO:0010575 9.48 IL1B PTGS2
15 response to vitamin D GO:0033280 9.46 IL1B PTGS2
16 ovulation GO:0030728 9.43 IL1B PTGS2
17 positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032725 9.4 IL18 IL1B
18 interleukin-6 production GO:0032635 9.37 IL18 IL1B
19 positive regulation of neuroinflammatory response GO:0150078 9.32 IL18 IL1B
20 positive regulation of fever generation GO:0031622 9.26 IL1B PTGS2
21 positive regulation of T-helper 1 cell cytokine production GO:2000556 9.16 IL18 IL1B
22 cellular response to mechanical stimulus GO:0071260 9.13 CASP1 IL1B PTGS2
23 cytokine-mediated signaling pathway GO:0019221 8.92 CASP1 IL18 IL1B PTGS2

Sources for Alcoholic Gastritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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