Aliases & Classifications for Alexithymia

MalaCards integrated aliases for Alexithymia:

Name: Alexithymia 12 15


External Ids:

Disease Ontology 12 DOID:0060131

Summaries for Alexithymia

Disease Ontology : 12 An agnosia that is a deficiency in understanding, processing, or describing emotions.

MalaCards based summary : Alexithymia is related to eating disorder and traumatic brain injury. An important gene associated with Alexithymia is SLC6A4 (Solute Carrier Family 6 Member 4), and among its related pathways/superpathways are cAMP signaling pathway and Lung fibrosis. The drugs Cycloserine and Ketamine have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and breast.

Wikipedia : 74 Alexithymia is a personal trait characterized by the subclinical inability to identify and describe... more...

Related Diseases for Alexithymia

Diseases related to Alexithymia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 406)
# Related Disease Score Top Affiliating Genes
1 eating disorder 31.1 SLC6A4 OXTR DRD2 COMT ANKK1
2 traumatic brain injury 31.1 IL6 DRD2 COMT
3 brain injury 31.0 IL6 DRD2 COMT
4 acute stress disorder 30.9 SLC6A4 OXT CRP
5 personality disorder 30.9 SLC6A4 HTR1A DRD2 COMT ANKK1
6 substance abuse 30.8 SLC6A4 HTR1A DRD2 COMT
7 anorexia nervosa 30.8 SLC6A4 OXT HTR1A COMT
8 borderline personality disorder 30.8 SLC6A4 HTR1A DRD2 COMT
9 somatoform disorder 30.8 SLC6A4 IL6 IL4 COMT
10 somatization disorder 30.8 SLC6A4 OXT
11 bulimia nervosa 30.7 SLC6A4 OXT DRD2 COMT
12 panic disorder 30.7 SLC6A4 IL6 HTR1A DRD2 COMT
13 alcohol use disorder 30.6 SLC6A4 HTR1A DRD2 COMT ANKK1
14 urticaria 30.5 IL6 IL4 CRP
15 fibromyalgia 30.4 SLC6A4 IL6 HTR1A DRD2 CRP COMT
16 migraine without aura 30.4 SLC6A4 HTR1A DRD2
17 pathological gambling 30.3 SLC6A4 HTR1A DRD2 COMT ANKK1
18 irritable bowel syndrome 30.3 SLC6A4 IL6 HTR1A CRP COMT
19 agoraphobia 30.3 SLC6A4 LOC110806262 HTR1A COMT
20 alcohol dependence 30.3 SLC6A4 OXT HTR1A DRD2 COMT ANKK1
21 mood disorder 30.3 SLC6A4 IL6 HTR1A DRD2 COMT
22 polysubstance abuse 30.3 DRD2 COMT
23 paranoid schizophrenia 30.3 SLC6A4 IL6 HTR1A COMT
24 cocaine abuse 30.3 SLC6A4 IL6 DRD2
25 neurotic disorder 30.3 SLC6A4 IL6 HTR1A
26 tobacco addiction 30.3 SLC6A4 DRD2 COMT ANKK1
27 generalized anxiety disorder 30.3 SLC6A4 HTR1A DRD2 CRP COMT
28 substance dependence 30.3 SLC6A4 IL6 DRD2 COMT ANKK1
29 post-traumatic stress disorder 30.3 SLC6A4 HTR1A DRD2 CRP COMT CCL4
30 atypical depressive disorder 30.2 SLC6A4 IL6 HTR1A CRP
31 agnosia 30.2 OXT IL6 HTR1A
32 cocaine dependence 30.1 SLC6A4 DRD2 COMT
33 chronic fatigue syndrome 30.0 SLC6A4 IL6 IL4 HTR1A COMT
34 sleep disorder 30.0 SLC6A4 IL6 HTR1A DRD2 CRP
35 sexual disorder 30.0 SLC6A4 OXT HTR1A DRD2
36 antisocial personality disorder 30.0 SLC6A4 LOC110806262 DRD2 COMT ANKK1
37 anxiety 30.0 SLC6A4 OXTR OXT IL6 HTR1A DRD2
38 tic disorder 30.0 SLC6A4 HTR1A DRD2 COMT
39 melancholia 29.9 SLC6A4 LOC110806262 HTR1A CRP
40 schizoaffective disorder 29.9 SLC6A4 HTR1A DRD2 COMT
41 gilles de la tourette syndrome 29.9 SLC6A4 HTR1A DRD2 COMT
42 sleep apnea 29.9 SLC6A4 IL6 CRP
43 asperger syndrome 29.9 SLC6A4 OXTR OXT COMT
44 hypoactive sexual desire disorder 29.9 OXT HTR1A
45 social phobia 29.9 SLC6A4 OXT LOC110806262 HTR1A DRD2 COMT
46 bipolar disorder 29.8 SLC6A4 IL6 HTR1A DRD2 CRP COMT
47 pulmonary disease, chronic obstructive 29.8 SLC6A4 IL6 IL4 CRP CCL3
48 migraine with or without aura 1 29.8 SLC6A4 OXT IL6 HTR1A DRD2 CRP
49 obsessive-compulsive disorder 29.8 SLC6A4 OXTR OXT IL6 HTR1A DRD2
50 periodontitis 29.7 IL6 IL4 CRP

Graphical network of the top 20 diseases related to Alexithymia:

Diseases related to Alexithymia

Symptoms & Phenotypes for Alexithymia

Drugs & Therapeutics for Alexithymia

Drugs for Alexithymia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 77)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Cycloserine Approved Phase 4 68-41-7 401 6234
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
3 Antidepressive Agents Phase 4
4 Neurotransmitter Agents Phase 4
5 Analgesics Phase 4
6 Excitatory Amino Acid Antagonists Phase 4
7 Anesthetics Phase 4
8 Anesthetics, Dissociative Phase 4
9 Antitubercular Agents Phase 4
10 Anti-Bacterial Agents Phase 4
11 Anesthetics, General Phase 4
12 Antibiotics, Antitubercular Phase 4
13 Anesthetics, Intravenous Phase 4
14 Antimetabolites Phase 4
Phenol Approved, Experimental Phase 3 108-95-2 996
Liraglutide Approved Phase 3 204656-20-2 44147092
Glucagon Approved Phase 3 16941-32-5
18 Hormones Phase 3
19 Hormone Antagonists Phase 3
20 Hypoglycemic Agents Phase 3
21 Incretins Phase 3
22 Glucagon-Like Peptide 1 Phase 3
Paroxetine Approved, Investigational Phase 1, Phase 2 61869-08-7 43815
Amitriptyline Approved Phase 1, Phase 2 50-48-6 2160
Pregabalin Approved, Investigational Phase 1, Phase 2 148553-50-8 5486971
Perphenazine Approved Phase 1, Phase 2 58-39-9 4748
Norepinephrine Approved Phase 1, Phase 2 51-41-2 439260
Zopiclone Approved Phase 2 43200-80-2 5735
29 Cytochrome P-450 Enzyme Inhibitors Phase 1, Phase 2
30 Psychotropic Drugs Phase 1, Phase 2
31 Serotonin Uptake Inhibitors Phase 1, Phase 2
32 Adrenergic Agents Phase 1, Phase 2
33 Analgesics, Non-Narcotic Phase 1, Phase 2
34 Venlafaxine Hydrochloride Phase 1, Phase 2
35 Serotonin and Noradrenaline Reuptake Inhibitors Phase 1, Phase 2
36 Antipsychotic Agents Phase 1, Phase 2
37 Antidepressive Agents, Tricyclic Phase 1, Phase 2
38 Amitriptyline, perphenazine drug combination Phase 1, Phase 2
39 Hypnotics and Sedatives Phase 2
Serotonin Investigational, Nutraceutical Phase 1, Phase 2 50-67-9 5202
Acetylcysteine Approved, Investigational Phase 1 616-91-1 12035
42 Anti-Infective Agents Phase 1
43 Vitamins Phase 1
44 Respiratory System Agents Phase 1
45 Antidotes Phase 1
46 Antioxidants Phase 1
47 Antiviral Agents Phase 1
48 Expectorants Phase 1
49 N-monoacetylcystine Phase 1
50 Protective Agents Phase 1

Interventional clinical trials:

(show top 50) (show all 54)
# Name Status NCT ID Phase Drugs
1 D-cycloserine for Relapse Prevention Following Intravenous Ketamine in Treatment-resistant Depression Unknown status NCT02772211 Phase 4 Ketamine;D-cycloserine;Placebo
2 Liraglutide 3.0mg/d for the Treatment of Binge Eating Disorder Terminated NCT03279731 Phase 3 Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml;Placebo
3 A Cross Over Randomized Controlled Trial of the Effect of Nasal Ocytocine on Cerebral Activations in Relation With Attachement in the General Population Unknown status NCT02847143 Phase 2 nasal oxytocin or placebo
4 Comparative Effectiveness of Newer Antidepressants in Combination With Pregabalin for Fibromyalgia Syndrome: A Controlled Randomized Study Completed NCT02451475 Phase 1, Phase 2 Amitriptyline;Venlafaxine;Paroxetine
5 Effectiveness of Nonspecific Methods of Treatment and Zopiclone for Chronic Insomnia Completed NCT03339583 Phase 2 Zopiclone
6 N-Acetylcysteine in the Treatment of Deliberate Self-Harm in Adolescents: An Open Label Pilot Study Completed NCT01111734 Phase 1 fMRI
7 Understanding Alexithymia Unknown status NCT00830752
8 Psychopathological Risk Factors Associated With Conversion From Mild Cognitive Impairment to Dementia Unknown status NCT01436552
9 Interaction Emotion-cognition in the Study of Literal and Figurative Language in Schizophrenia and Bipolar Disorders: Behavioral and Electrophysiological Studies Unknown status NCT02805088
10 Emotional and Non-emotional Regulation in Patients With Emotional Instability Personality Disorder (EIP) and Attention Deficit Hyperactivity Disorder (ADHD) Symptoms Unknown status NCT02797873
11 Alexithymia Frequency and Interhemispheric Transfer in Patients With a First Demyelinating Event: Initial Phase of Multiple Sclerosis Completed NCT03796247
12 Alexithymia in Ankylosing Spondylitis Completed NCT04320459
13 Symptom, Alexithymia and Self-image Outcomes of Mentalization-Based Treatment for Borderline Personality Disorder: a Naturalistic Study Completed NCT03295838
14 Functional Neuroanatomy and Regional Metabolism Before and After Treatment With Duloxetine: A Combined fMRI and MRS Study in Major Depression Completed NCT02658617
15 Decoupling as Internet Based Intervention: an Randomized Controlled Study to Treat Trichotillomania Completed NCT02044237
16 Asthma, Smoking, Emotional Deficits Completed NCT03312673
17 Moderating Impact of Various Emotion Personality Factors on Salivary Cortisol Completed NCT00451126
18 Affective Learning in Disabled Health Training of Turkish Nursing Students: A Randomized Controlled Study Completed NCT04365894
19 EPidemiological Study In Patients With Recently DiagnosEd PSOriasis: Clinical Assessment and Psychosocial Impact of This Disease Completed NCT01964443
20 The Emotion Builder: An Intervention for Emotional Deficits After Brain Injury Completed NCT02432300
21 Emotion Regulation Group Skills Training: A Pilot Study of an add-on Treatment for Eating Disorders in a Clinical Setting Completed NCT04148014
22 Attention Bias Modification Treatment for Warzone-Related PTSD: A Randomized Clinical Trial Magnetoencephalography Study Completed NCT01564667
23 Evaluation of Smell and Taste in Patients With Fibromyalgia Completed NCT03823937
24 Online Assessment for Therapy Expectation and Quality of Life and Online Therapy of Depression Completed NCT02112266
25 Oculomotor and Neurophysiological Markers of Emotion Regulation and Attachment Styles in Adolescence Completed NCT02851810
26 Research Project About Psychological Strain, Quality of Life and Emotional Awareness in Patients With Tinnitus Completed NCT01837368
27 Study of Psychological and Sociological Predisposing the Development of Chronic Pain After Surgery in Women With Resectable Breast Cancer Completed NCT00466830
28 Phase 1 Study of Immune, Psychometric and Sociodemographic Patterns in Pain Patients Classified by DSM-IV Completed NCT01106339
29 Happiness in Flanders: A Randomized, Wait-List Controlled Study Completed NCT02041741
30 Effectiveness of a Psychological Intervention Focused on Expressive Writing in Patients Undergoing to Kidney Transplant Completed NCT04143178
31 "Rezeptive Musiktherapie Bei Depression - Eine Randomisierte, Placebokontrollierte Studie" / Receptive Music Therapy in Depression: A Randomized Placebo-Controlled Trial Completed NCT00644527
32 Electrophysiological Correlates of Emotional and Crossmodal Stimuli Processing Among Alcohol-dependent Participants : Exploration of the Peripheral Presentation Effect Completed NCT01633905
33 Disorders of Emotional Communication in Patient With Cerebellar Dysfunction Completed NCT02106819
34 Impact of Art Therapy on Alexithymia in People With Alcohol Use Disorder Recruiting NCT04206930
35 Training to Reconnect With Emotional Awareness Therapy Recruiting NCT03414463
36 The Effects of Different Exercise Approaches on Physical and Cognitive Variables in Patients With Chronic Low Back Pain Recruiting NCT04000685
37 Influence of Main Psychological and Social Factors on Primary Headaches Recruiting NCT03577548
38 Compensatory Brain Mechanisms for Amygdala-associated Cognitive Dysfunction: Potential Role of the Cortical Mirror Neuron System Recruiting NCT03723733
39 Positive Emotion Regulation Training in Children, Adolescents and Young Adults With and Without Developmental Disorder Recruiting NCT02898298
40 The Modulatory Effect of Oxytocin on Attentional Processing of Emotional Faces Recruiting NCT04413786 oxytocin treatment;placebo treatment
41 Pharmaco(Epi)Genetic Study of Obsessive-Compulsive Disorder Recruiting NCT02431845 SSRIs
42 Effectiveness of Buprenorphine/Naloxone in Patients With Chronic Pain and Iatrogenic Opioid Dependence Recruiting NCT02882412
43 Psychological Predictors of Post-surgical Recovery in Colorectal Cancer Patients: a Pilot Cohort Study Recruiting NCT03781193
44 Childhood Trauma in Schizophrenia: Exploration of Links Between Gene Expression, Cerebral Morphology and Symptomatology. SCHIZO' TRAUMA Recruiting NCT03355781
45 Neurophysiological, Biomolecular and Psychological Aspects of Erenumab Treatment in Chronic Migraine: an Open Label, Hypothesis Generator Study Recruiting NCT04361721 Erenumab
46 Disentangling Emotional Processing From Regulation in Bulimia Nervosa Recruiting NCT03781921
47 The 9-month Follow-up Study for the Patients of Illicit Substance Use Disorder After Receiving the Different Psychosocial Intervention Recruiting NCT04426565
48 the Effects of Oxytocin on Negative Symptoms of Schizophrenia and Its Behavioral and Neurobiological Mechanisms Recruiting NCT03662425 Oxytocin;Saline;Oxytocin;Saline
49 Efficacy of Eye Movement Desensitization and Reprocessing (EMDR) Plus Broad Form of Enhanced Cognitive Behavioural Therapy (CBT-Eb) in Patients With Eating Disorders. A Randomized Controlled Trial Recruiting NCT03156959
50 Behavioral Exploration of Cognitive and Emotional Alterations in Adult Individuals Exposed to Alcohol During the Prenatal Period Active, not recruiting NCT03793920

Search NIH Clinical Center for Alexithymia

Genetic Tests for Alexithymia

Anatomical Context for Alexithymia

MalaCards organs/tissues related to Alexithymia:

Brain, Testes, Breast, Heart, Eye, Amygdala, Kidney

Publications for Alexithymia

Articles related to Alexithymia:

(show top 50) (show all 2939)
# Title Authors PMID Year
The role of alexithymia in the mental health problems of home-quarantined university students during the COVID-19 pandemic in China. 61
32518435 2020
The role of alexithymia in social cognition: Evidence from a non-clinical population. 61
32560944 2020
The rs6311 of serotonin receptor 2A (5-HT2A) gene is associated with alexithymia and mental health. 61
32553368 2020
Attachment to Parents and Peers and Adolescent Mental Health: The Mediating Role of Alexithymia. 61
31960177 2020
Prospective pilot study to identify psychological factors influencing peri-operative pain in total knee arthroplasty (TKA). 61
32266414 2020
Professional quality of life and burnout amongst radiation oncologists: The impact of alexithymia and empathy. 61
32417347 2020
The association between communication impairments and acquired alexithymia in chronic stroke patients. 61
32576080 2020
Alexithymia and self-harm: A review of nonsuicidal self-injury, suicidal ideation, and suicide attempts. 61
32279008 2020
The effects of an expressive writing intervention on pregnancy rates, alexithymia and psychophysical health during an assisted reproductive treatment. 61
31549861 2020
Gender Differences in Child Abuse, Emotional Processing Difficulties, Alexithymia, Psychological Symptoms and Behavioural Problems among Chinese Adolescents. 61
31900820 2020
Corticospinal inhibition and alexithymia in multiple sclerosis patients-An exploratory study. 61
32172214 2020
Personality and Psychopathology in Adults with Noonan Syndrome. 61
31560100 2020
The Relationship Between Parental Care and Pain in Children With Headache: A Narrative Review. 61
32474926 2020
Depression in Psoriatic Arthritis: Dimensional Aspects and Link with Systemic Inflammation. 61
32323218 2020
Factors associated with anxiety among the Lebanese population: the role of alexithymia, self-esteem, alcohol use disorders, emotional intelligence and stress and burnout. 61
32031427 2020
Empathy, Alexithymia, and Theory of Mind in Borderline Personality Disorder. 61
32520852 2020
Construct validity of the Levels of Emotional Awareness Scale among women high in eating disorder symptoms: a cross-sectional study. 61
32564219 2020
Alexithymia, resilience, somatic sensations and their relationships with suicide ideation in drug naïve patients with first-episode major depression: An exploratory study in the "real world" everyday clinical practice. 61
31402575 2020
Alexithymic Traits and Somatic Symptoms in Children and Adolescents: a Screening Approach to Explore the Mediation Role of Depression. 61
32020499 2020
Evaluating Interoceptive Crossover between emotional and physical symptoms. 61
32544342 2020
[The Measurement of Psychological Mindedness: a validation study of the German version of the Balanced Index of Psychological Mindedness (BIPM)]. 61
32552589 2020
Social media use disorder and loneliness: any association between the two? Results of a cross-sectional study among Lebanese adults. 61
32487222 2020
What is alexithymia? Using factor analysis to establish its latent structure and relationship with fantasizing and emotional reactivity. 61
32463926 2020
Comments on "Prevalence of alexithymia and associated factors among medical students at King Abdulaziz University: a cross-sectional study". 61
32493046 2020
The cognitive-interpersonal model of disordered eating: A test of the mediating role of alexithymia. 61
31989726 2020
Alexithymia, Emotion-Regulation Strategies, and Traumatic Experiences in Prenatally Cocaine-Exposed Young Adults. 61
32436341 2020
Prevalence and associated factors of alexithymia among Chinese adolescents in Hong Kong. 61
32505928 2020
Alexithymia is associated with cognitive impairment in patients with Parkinson's disease. 61
32579310 2020
Alexithymia, infertility-related stress and quality of life in women undergoing an Assisted Reproductive Treatment. 61
32472734 2020
Alexithymia and automatic processing of facial emotions: behavioral and neural findings. 61
32471365 2020
Individuals with Autism Share Others' Emotions: Evidence from the Continuous Affective Rating and Empathic Responses (CARER) Task. 61
32468395 2020
Disease Severity Is Associated with Alexithymia in Patients with Atopic Dermatitis. 61
32369808 2020
Association Between Alexithymia and Immature Coping Styles Is Mediated by Self-Inconsistency and Is Correlated to Obsessive-Compulsive Symptoms. 61
31977717 2020
The Influence of Alexithymia on Alcohol Craving, Health-Related Quality of Life and Gender in Alcohol-Dependent Outpatients. 61
32429771 2020
The ability to understand emotions is associated with interoception-related insular activation and white matter integrity during aging. 61
31994733 2020
Distinct associations of DSM-5 Somatic Symptom Disorder, the Diagnostic Criteria for Psychosomatic Research-Revised (DCPR-R) and symptom severity in patients with irritable bowel syndrome. 61
32199282 2020
The Emotion Regulation Questionnaire: Psychometric Properties in General Community Samples. 61
30714818 2020
A comparison of patients with somatic symptom disorder attending psychiatric services and those unwilling to attend psychiatric services. 61
32474346 2020
Sex differences in emotional insight after traumatic brain injury. 61
32445846 2020
Ideal cardiovascular health in adolescents and young adults is associated with alexithymia over two decades later: Findings from the cardiovascular risk in Young Finns Study: Department: Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland. 61
32413709 2020
Relative stability of alexithymia and openness to emotions in one psychiatric day hospital setting. 61
32285578 2020
The influence of alexithymia on memory for emotional faces and realistic social interactions. 61
32268841 2020
Exploring the links between alexithymia, empathy and schizotypy in college students using network analysis. 61
32249676 2020
Alexithymia, empathy, negative affect and physical symptoms in patients with asthma. 61
32285550 2020
Attachment representations and alexithymia in community adolescents with binge-eating attitudes. 61
32277425 2020
Relevant associations between alexithymia and health-literacy in persons with psoriasis. 61
32286098 2020
Social media use disorder and alexithymia: Any association between the two? Results of a cross-sectional study among Lebanese adults. 61
32239534 2020
Alexithymia, Prior Trauma, Alcohol Use, and Sexual Aggression Perpetration: A Cross-Cultural Comparison of a Moderated Mediation Model. 61
32248750 2020
The relation of alexithymia and attachment with type 1 diabetes management in adolescents: a gender-specific analysis. 61
32252831 2020
Alexithymia as a Predictor of Arousal and Affect Dysregulations when Batterers with Attention Deficit Hyperactivity Disorder Cope with Acute Stress. 61
32244844 2020

Variations for Alexithymia

Expression for Alexithymia

Search GEO for disease gene expression data for Alexithymia.

Pathways for Alexithymia

Pathways related to Alexithymia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
2 11.26 IL6 IL4 CCL4 CCL3
3 10.95 IL6 IL4 CCL4 CCL3
4 10.4 IL6 IL4
Show member pathways

GO Terms for Alexithymia

Biological processes related to Alexithymia according to GeneCards Suite gene sharing:

(show all 30)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.11 TAS2R38 OXTR OXT IL6 IL4 HTR1A
2 G protein-coupled receptor signaling pathway GO:0007186 10.09 TAS2R38 OXTR OXT HTR1A DRD2 CCL4
3 positive regulation of gene expression GO:0010628 9.98 SLC6A4 IL6 IL4 CRP CCL3
4 positive regulation of cold-induced thermogenesis GO:0120162 9.81 OXTR OXT IL4
5 female pregnancy GO:0007565 9.8 OXTR OXT COMT
6 memory GO:0007613 9.78 SLC6A4 OXTR OXT
7 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.75 IL6 IL4 CRLF1
8 social behavior GO:0035176 9.69 SLC6A4 OXTR OXT
9 dopamine metabolic process GO:0042417 9.65 DRD2 COMT
10 monocyte chemotaxis GO:0002548 9.65 IL6 CCL4 CCL3
11 cytokine-mediated signaling pathway GO:0019221 9.65 IL6 IL4 CRLF1 CCL4 CCL3
12 positive regulation of renal sodium excretion GO:0035815 9.64 OXT DRD2
13 grooming behavior GO:0007625 9.64 OXT DRD2
14 maternal behavior GO:0042711 9.62 OXTR OXT
15 negative regulation by host of viral transcription GO:0043922 9.62 CCL4 CCL3
16 sleep GO:0030431 9.61 OXTR OXT
17 response to cocaine GO:0042220 9.61 OXTR OXT DRD2
18 regulation of behavior GO:0050795 9.6 HTR1A CCL3
19 negative regulation of lipid storage GO:0010888 9.59 IL6 CRP
20 drinking behavior GO:0042756 9.57 OXT DRD2
21 positive regulation of uterine smooth muscle contraction GO:0070474 9.56 OXTR OXT
22 positive regulation of natural killer cell chemotaxis GO:2000503 9.54 CCL4 CCL3
23 response to amphetamine GO:0001975 9.54 OXTR OXT DRD2
24 negative regulation of gastric acid secretion GO:0060455 9.52 OXTR OXT
25 regulation of sensory perception of pain GO:0051930 9.5 OXT COMT CCL3
26 positive regulation of penile erection GO:0060406 9.49 OXTR OXT
27 positive regulation of norepinephrine secretion GO:0010701 9.4 OXTR OXT
28 response to toxic substance GO:0009636 9.26 SLC6A4 DRD2 CCL4 CCL3
29 regulation of digestive system process GO:0044058 9.16 OXTR OXT
30 sperm ejaculation GO:0042713 8.8 SLC6A4 OXTR OXT

Molecular functions related to Alexithymia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serotonin binding GO:0051378 9.26 SLC6A4 HTR1A
2 CCR5 chemokine receptor binding GO:0031730 9.16 CCL4 CCL3
3 cytokine activity GO:0005125 9.02 IL6 IL4 CRLF1 CCL4 CCL3
4 CCR1 chemokine receptor binding GO:0031726 8.96 CCL4 CCL3

Sources for Alexithymia

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
54 Novoseek
57 OMIM via Orphanet
61 PubMed
70 Tocris
72 UMLS via Orphanet
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