MCID: ALK005
MIFTS: 11

Alk+ Histiocytosis

Categories: Immune diseases, Rare diseases

Aliases & Classifications for Alk+ Histiocytosis

MalaCards integrated aliases for Alk+ Histiocytosis:

Name: Alk+ Histiocytosis 54
Anaplastic Lymphoma Kinase Positive Histiocytosis 54

Classifications:



Summaries for Alk+ Histiocytosis

MalaCards based summary : Alk+ Histiocytosis, also known as anaplastic lymphoma kinase positive histiocytosis, is related to histiocytosis and langerhans cell sarcoma. An important gene associated with Alk+ Histiocytosis is CD1A (CD1a Molecule), and among its related pathways/superpathways are Interleukin-4 and 13 signaling and Dendritic Cells Developmental Lineage Pathway.

Related Diseases for Alk+ Histiocytosis

Diseases related to Alk+ Histiocytosis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 histiocytosis 29.8 CD1A CD207
2 langerhans cell sarcoma 9.9 CD1A CD207
3 hodgkin's lymphoma, lymphocytic depletion 9.9 ALK FSCN1
4 myofibroma 9.8 CD1A F13A1
5 dendritic cell tumor 9.6 CD1A CD207 FSCN1
6 non-langerhans-cell histiocytosis 9.6 CD207 F13A1
7 reticulohistiocytic granuloma 9.6 CD207 FSCN1
8 juvenile xanthogranuloma 9.6 F13A1 FSCN1
9 langerhans cell histiocytosis 9.5 CD1A CD207 F13A1

Graphical network of the top 20 diseases related to Alk+ Histiocytosis:



Diseases related to Alk+ Histiocytosis

Symptoms & Phenotypes for Alk+ Histiocytosis

Drugs & Therapeutics for Alk+ Histiocytosis

Search Clinical Trials , NIH Clinical Center for Alk+ Histiocytosis

Genetic Tests for Alk+ Histiocytosis

Anatomical Context for Alk+ Histiocytosis

Publications for Alk+ Histiocytosis

Articles related to Alk+ Histiocytosis:

# Title Authors Year
1
ALK+ histiocytosis: a novel type of systemic histiocytic proliferative disorder of early infancy. ( 18660380 )
2008

Variations for Alk+ Histiocytosis

Expression for Alk+ Histiocytosis

Search GEO for disease gene expression data for Alk+ Histiocytosis.

Pathways for Alk+ Histiocytosis

Pathways related to Alk+ Histiocytosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.01 F13A1 FSCN1
2 10.49 CD1A CD207

GO Terms for Alk+ Histiocytosis

Sources for Alk+ Histiocytosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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