MCID: ALK005
MIFTS: 11

Alk+ Histiocytosis

Categories: Immune diseases, Rare diseases

Aliases & Classifications for Alk+ Histiocytosis

MalaCards integrated aliases for Alk+ Histiocytosis:

Name: Alk+ Histiocytosis 20
Anaplastic Lymphoma Kinase Positive Histiocytosis 20

Classifications:



Summaries for Alk+ Histiocytosis

MalaCards based summary : Alk+ Histiocytosis, also known as anaplastic lymphoma kinase positive histiocytosis, is related to histiocytosis and juvenile xanthogranuloma. An important gene associated with Alk+ Histiocytosis is ALK (ALK Receptor Tyrosine Kinase), and among its related pathways/superpathways are Interleukin-4 and 13 signaling and Dendritic Cells Developmental Lineage Pathway. Related phenotype is respiratory system.

Related Diseases for Alk+ Histiocytosis

Graphical network of the top 20 diseases related to Alk+ Histiocytosis:



Diseases related to Alk+ Histiocytosis

Symptoms & Phenotypes for Alk+ Histiocytosis

MGI Mouse Phenotypes related to Alk+ Histiocytosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 respiratory system MP:0005388 8.92 ALK CD207 F13A1 FSCN1

Drugs & Therapeutics for Alk+ Histiocytosis

Search Clinical Trials , NIH Clinical Center for Alk+ Histiocytosis

Genetic Tests for Alk+ Histiocytosis

Anatomical Context for Alk+ Histiocytosis

Publications for Alk+ Histiocytosis

Articles related to Alk+ Histiocytosis:

# Title Authors PMID Year
1
ALK+ histiocytosis: a novel type of systemic histiocytic proliferative disorder of early infancy. 61
18660380 2008

Variations for Alk+ Histiocytosis

Expression for Alk+ Histiocytosis

Search GEO for disease gene expression data for Alk+ Histiocytosis.

Pathways for Alk+ Histiocytosis

Pathways related to Alk+ Histiocytosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.01 FSCN1 F13A1
2 10.49 CD207 CD1A

GO Terms for Alk+ Histiocytosis

Sources for Alk+ Histiocytosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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