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MCID: ALL012
MIFTS: 24

Allergic Angiitis

Categories: Immune diseases, Rare diseases
Tissues Related diseases Publications Drugs
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Aliases & Classifications for Allergic Angiitis

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MalaCards integrated aliases for Allergic Angiitis:

Name: Allergic Angiitis 52
Churg-Strauss Syndrome 71

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Immune diseases
See all MalaCards categories (disease lists)


External Ids:

UMLS 71 C0008728
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Summaries for Allergic Angiitis

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MalaCards based summary : Allergic Angiitis, also known as churg-strauss syndrome, is related to churg-strauss syndrome and vasculitis. The drugs Cyclophosphamide and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include neutrophil, lung and heart.

Wikipedia : 74 Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as allergic granulomatosis, is an... more...

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Related Diseases for Allergic Angiitis

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Diseases related to Allergic Angiitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 churg-strauss syndrome 12.0
2 vasculitis 10.3
3 hypereosinophilic syndrome 10.3
4 purpura 10.2
5 mononeuritis multiplex 10.1
6 kaposi sarcoma 9.9
7 lymphoma 9.9
8 henoch-schoenlein purpura 9.9
9 sarcoma 9.9
10 bronchopneumonia 9.9
11 dermatitis 9.9
12 spindle cell sarcoma 9.9
13 myocarditis 9.9
14 lupus erythematosus 9.9
15 polyarteritis nodosa 9.9
16 lymphosarcoma 9.9

Graphical network of the top 20 diseases related to Allergic Angiitis:



Diseases related to Allergic Angiitis
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Symptoms & Phenotypes for Allergic Angiitis

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Drugs & Therapeutics for Allergic Angiitis

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Drugs for Allergic Angiitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 84)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyclophosphamide Approved, Investigational Phase 4 50-18-0, 6055-19-2 2907
2
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
3
leucovorin Approved Phase 4 58-05-9 6006 143
4
Methotrexate Approved Phase 4 59-05-2, 1959-05-2 126941
5
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
6
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
7
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
8 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
9
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
10
Mycophenolic acid Approved Phase 4 24280-93-1 446541
11
rituximab Approved Phase 4 174722-31-7 10201696
12
Azathioprine Approved Phase 4 446-86-6 2265
13
Hydroxychloroquine Approved Phase 4 118-42-3 3652
14
Povidone Approved Phase 4 9003-39-8
15
Folic acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
16
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
17 Hormones Phase 4
18 Antineoplastic Agents, Hormonal Phase 4
19 Hormone Antagonists Phase 4
20 Anti-Inflammatory Agents Phase 4
21 Gastrointestinal Agents Phase 4
22 Dermatologic Agents Phase 4
23 Alkylating Agents Phase 4
24 Folic Acid Antagonists Phase 4
25 Vitamin B Complex Phase 4
26 Folate Phase 4
27 Vitamin B9 Phase 4
28 Methylprednisolone Acetate Phase 4
29 Antiemetics Phase 4
30 Neuroprotective Agents Phase 4
31 Protective Agents Phase 4
32 Antitubercular Agents Phase 4
33 Anti-Bacterial Agents Phase 4
34 Antibiotics, Antitubercular Phase 4
35 Immunologic Factors Phase 4
36 glucocorticoids Phase 4
37 Antineoplastic Agents, Immunological Phase 4
38 Immunosuppressive Agents Phase 4
39 Antimetabolites Phase 4
40 Antirheumatic Agents Phase 4
41 Anti-Infective Agents Phase 4
42 Antiparasitic Agents Phase 4
43 Antiprotozoal Agents Phase 4
44 Antimalarials Phase 4
45 Benralizumab Approved, Investigational Phase 3 1044511-01-4
46 Respiratory System Agents Phase 3
47 Pharmaceutical Solutions Phase 3
48 Anti-Asthmatic Agents Phase 3
49 Immunoglobulins Phase 3
50 Antibodies Phase 3

Interventional clinical trials:

(show all 44)
# Name Status NCT ID Phase Drugs
1 CHUSPAN SCS BP Treatment of Churg–Strauss Syndrome Without Poor-Prognosis Factors: a Prospective Randomized Study in 72 Patients. Unknown status NCT00399399 Phase 4 azathioprine;cyclophosphamide
2 Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years Comparison of Two Strategies Combining Steroids With or Without Immunosuppressants Completed NCT00307671 Phase 4 prednisone, methylprednisolone,cyclophosphamides;Cyclophosphamide, Azathioprine,prednisone,methylprednisolone;Mycophenolate mofetil,methotrexate
3 MAINtenance of Remission With RITuximab Versus Azathioprine for Patients With Newly-diagnosed or Relapsing Eosinophilic Granulomatosis With Polyangiitis. A Prospective, Randomized, Controlled, Double-blind Study: the MAINRITSEG Trial Recruiting NCT03164473 Phase 4 Rituximab;Azathioprine;Placebo-rituximab;Placebo-azathioprine
4 Hydroxychloroquine in ANCA Vasculitis Evaluation - A Multicentre, Randomised, Double-blind, Placebo-controlled Trial Not yet recruiting NCT04316494 Phase 4 Hydroxychloroquine;Placebo
5 A Double-blind, Randomised, Placebo-controlled Study to Investigate the Efficacy and Safety of Mepolizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis in Subjects Receiving Standard of Care Therapy Completed NCT02020889 Phase 3 Placebo
6 Evaluation of a New Treatment Strategy for Patients With Microscopic Polyangiitis, Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome) Without Poor Prognosis Factors Completed NCT00647166 Phase 3 corticosteroid and azathioprine;corticosteroid and placebo
7 Evaluation of Rituximab-based Regimen Compared to Conventional Therapeutic Strategy For Remission Induction In Patients With Newly-Diagnosed or Relapsing Eosinophilic Granulomatosis With Polyangiitis. Prospective, Randomized, Controlled, Double-blind Study Recruiting NCT02807103 Phase 3 Rituximab;Placebo-rituximab;Cyclophosphamide;Placebo-cyclophosphamide
8 A Randomized, Double-blind, Active-controlled 52-week Study With an Open-label Extension to Evaluate the Efficacy and Safety of Benralizumab Compared to Mepolizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis (EGPA) in Patients Receiving Standard of Care Therapy Recruiting NCT04157348 Phase 3
9 Mepolizumab Long-term Access Programme for Subjects Who Participated in Study MEA115921 (Placebo-controlled Study of Mepolizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis in Subjects Receiving Standard-of-care Therapy) Active, not recruiting NCT03298061 Phase 3 Mepolizumab;Prednisolone
10 Intravenous Immunoglobulin After Relapse in Vasculitis (Microscopic Polyangiitis, Wegener’s Granulomatosis and SHURG-STRAUSS Syndrome) During and After Corticosteroids and Immunosuppressant Therapies a Multicenter Prospective Trial Terminated NCT00307658 Phase 3 Intravenous immunoglobulins (human immunoglobulins G)
11 Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing Vasculitides. A Randomized Controlled Trial. Unknown status NCT00751517 Phase 2 Methotrexate;Cyclophosphamide
12 Open-Label, to Evaluate the Efficacy and Safety of Reslizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis (EGPA) Study: RITE Study Unknown status NCT02947945 Phase 2 Reslizumab
13 A Phase II, Single Center Open Label, Prospective Trial to Evaluate the Efficacy and Safety of Mepolizumab for Patients With Refractory or Relapsing Churg Strauss Syndrome Completed NCT00716651 Phase 2 mepolizumab
14 Mepolizumab As a Steroid Sparing Treatment Option in the Churg Strauss Syndrome Completed NCT00527566 Phase 1, Phase 2
15 A Phase I/II Study of the Effect of Intravenous Anti-IL-5 (Mepolizumab) SB 240563 on the Outcome and Management of Hypereosinophilic Syndromes Completed NCT00266565 Phase 1, Phase 2 Mepolizumab
16 Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis Recruiting NCT03482479 Phase 2 Naltrexone Hydrochloride
17 A Pilot Study on the Use of Rituximab in the Treatment of Churg- Strauss Syndrome With Renal Involvement Terminated NCT00424749 Phase 2 Rituximab;Prednisone
18 A Pilot Study Examining the Effect of Abatacept in ANCA Associated Vasculitis Terminated NCT00482066 Phase 2 Abatacept (Orencia)
19 High Dose Immune Suppression With Hematopoietic Stem Cell Support in Refractory Vasculitis, Necrotizing Vasculitis, Neurovascular Behcet's Disease, and Sjogren's Syndrome Terminated NCT00278512 Phase 1 Cyclophosphamide;ATG (rabbit);G-CSF;Campath-1h;Fludarabine;Tacrolimus;Mesna
20 Eosinophilic Granulomatosis With Polyangiitis Cohort Unknown status NCT03036670
21 Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases Unknown status NCT00006055 anti-thymocyte globulin;cyclophosphamide;cyclosporine;filgrastim;methylprednisolone;prednisone
22 A Qualitative Study Using Interviews With Patients Who Have Anti-neutrophil Cytoplasm Antibody (ANCA) Associated Vasculitis, to Develop a Patient Reported Outcome (PRO) Measure Unknown status NCT01729624
23 ACR/EULAR Endorsed Study to Develop New Diagnostic and Classification Criteria for Primary Systemic Vasculitis Unknown status NCT01066208
24 Chronic Childhood Vasculitis: Characterizing the Individual Rare Diseases to Improve Patient Outcomes Unknown status NCT02006134
25 Infliximab Versus Rituximab in Systemic Necrotizing Vasculitides With Positive ANCA After Relapse or Resistant Immunosuppressant Therapies Completed NCT00307593 Infliximab;Rituximab
26 Reproductive Health in Men and Women With Vasculitis Completed NCT02176070
27 Educational Needs of Patients With Systemic Vasculitis- an International Survey Completed NCT02190929
28 Illness Perception, Fatigue, and Function in Systemic Vasculitis (The VCRC Vasculitis Perception (VIP) Study) Completed NCT02190916
29 The Journey of Patients With Vasculitis From First Symptom to Diagnosis Completed NCT03410290
30 VCRC Validation of Patient-Reported Diagnostic Data Completed NCT02190942
31 The ANCA Vasculitis Questionnaire (AAV-PRO©) Completed NCT02507024
32 The Serum Eosinophil Cationic Protein Levels in Behçet's Disease and Its Relation to the Clinical Activity Completed NCT01584778
33 Clinical Transcriptomics in Systemic Vasculitis (CUTIS) Recruiting NCT03004326
34 Urinary CD4+ Effector Memory T Cells as Biomarkers for Prediction of Outcome in ANCA Glomerulonephritis Recruiting NCT04320667
35 The Vasculitis Pregnancy Registry (V-PREG) Recruiting NCT02593565
36 VCRC Tissue Biorepository Collection Protocol Recruiting NCT02967068
37 Urinary T Lymphocytes Predict Renal Flares in Patients With Inactive Anti-neutrophil Cytoplasmic Antibody (ANCA) Associated Glomerulonephritis Recruiting NCT04428398
38 Longitudinal Protocol for Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) Recruiting NCT00315380
39 Clinical and Echocardiographic Evaluation of Patients With Granulomatosis With Polyangiitis Recruiting NCT03782870
40 NUCALA ® Subcutaneous Injection Special Drug Use Investigation (EGPA, Long-term） Active, not recruiting NCT03557060 Nucala
41 VCRC Genetic Repository One-Time DNA Protocol Active, not recruiting NCT01241305
42 A Local Interventional Study in a Cohort of Patients With GPA, MPA and EGPA (PART 2 of "Vitamin D Status in ANCA-associated Vasculitis: Analysis of RDCRN-VCRC and Local Clinic Cohorts of Patients With GPA, MPA and EGPA") Not yet recruiting NCT04280601
43 A Pilot Study of Immuno-ablation With Chemoimmunoradiation Followed by Autologous Hematopoietic Progenitor Cell (HPC) Transplant for Adult Subjects With Churg-Strauss Syndrome Terminated NCT02728271 Early Phase 1
44 Defining Immune Tolerance in ANCA-associated Vasculitis (AAV) Terminated NCT01934504

Search NIH Clinical Center for Allergic Angiitis

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Genetic Tests for Allergic Angiitis

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Anatomical Context for Allergic Angiitis

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MalaCards organs/tissues related to Allergic Angiitis:

40
Neutrophil, Lung, Heart, Testes, T Cells, Skin, Colon
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Publications for Allergic Angiitis

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Articles related to Allergic Angiitis:

(show top 50) (show all 1992)
# Title Authors PMID Year
1
Multiple ulcerations and perforation in the small intestine after steroid treatment in eosinophilic granulomatosis with polyangiitis: a case report and literature review. 61
32151788 2020
2
Retinal artery occlusion followed by contralateral amaurosis fugax in association with eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome). 61
32309675 2020
3
Definite IgG4-related disease had no overlap with eosinophilic granulomatosis with polyangiitis in Korean patients: a pilot study in one centre. 61
32367405 2020
4
[A perimyocarditis revealing eosinophilic granulomatosis with polyangiitis]. 61
32265026 2020
5
Effects of surgery and topical medication on eosinophilic granulomatosis with polyangiitis with otitis media and sinusitis: a case report. 61
32345078 2020
6
Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome) masquerading as acute coronary syndrome. 61
32409371 2020
7
Syndrome of inappropriate antidiuretic hormone associated with eosinophilic granulomatosis and polyangiitis. 61
32209573 2020
8
Review of montelukast use over the past 20 years and monitoring of its effects. 61
32023405 2020
9
The continuous rediscovery and the benefit-risk ratio of thioguanine, a comprehensive review. 61
32090622 2020
10
[SYSTEMIC REVIEW OF EOSINOPHILIC DERMATOSES PATIENTS TREATED WITH TNF-Α INHIBITORS AND USTEKINUMAB]. 61
31930806 2020
11
Pathophysiology of ANCA-associated vasculitis. 61
32493021 2020
12
How to improve the histopathological diagnosis of systemic vasculitides in daily practice? 61
32493022 2020
13
[Mononeuritis Multiplex: A Diagnostic Challenge]. 61
32456580 2020
14
Recurrent bilateral eyelid and conjunctival granulomatosis in Churg-Strauss syndrome. 61
32008029 2020
15
A Case of Cutaneous Arteritis Presenting as Infiltrated Erythema in Eosinophilic Granulomatosis With Polyangiitis: Features of the Unique Morphological Evolution of Arteritis as a Diagnostic Clue. 61
31634169 2019
16
Idiopathic Orbital Pseudotumor Preceding Systemic Inflammatory Disease in Children. 61
31743405 2019
17
Allergic bronchopulmonary aspergillosis. 61
31690385 2019
18
Co-occurrence of PLA2R-positive membranous nephropathy without crescents, and PR3-positive eosinophilic granulomatosis with polyangiitis
. 61
31347497 2019
19
Update on eosinophilic granulomatosis with polyangiitis. 61
31266709 2019
20
Eosinophilic Granulomatosis with Polyangiitis: Experiences in Korean Patients. 61
31347324 2019
21
Cutaneous Vasculitis as Early Presentation of Eosinophilic Granulomatosis with Polyangiitis without Systemic Symptoms. 61
31360325 2019
22
Neurological Manifestations Do not Affect Cumulative Survival in Indian Patients with Antineutrophil Cytoplasmic Antibody Associated Vasculitis. 61
31512630 2019
23
Causes of eosinophilic ascites - A systematic review. 61
30864403 2019
24
Eosinophilic granulomatosis with polyangiitis in a Nigerian woman. 61
31217209 2019
25
A case of repetitive myocardial infarction with unobstructed coronaries due to Churg-Strauss syndrome. 61
31449602 2019
26
Targeted immunotherapy strategies in ANCA-associated vasculitis. 61
30201478 2019
27
[Current treatment of eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)]. 61
30627842 2019
28
[Unexpected death due to eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)]. 61
30720008 2019
29
Treatment of ANCA-associated vasculitides: Certainties and controversies. 61
30981399 2019
30
Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis Causes Aortic Valve Degeneration and Severe Aortic Regurgitation. 61
30930460 2019
31
Ultrasound diagnosis of typhlitis. 61
30367357 2019
32
Massive Myocardial Necrosis due to Churg-Strauss Syndrome. 61
29884587 2019
33
Eosinophilic granulomatosis with polyangiitis in a continuous flow left ventricular assist device patient: a case report and review of literature. 61
30684748 2019
34
Immunoglobulin G4-Related Disease Presenting with Clinical Similarity to Churg-Strauss Syndrome. 61
30772966 2019
35
Rare Manifestations of Churg-Strauss Syndrome with Mediastinal and Hilar Lymphadenopathies: Report of an Autopsy Case. 61
29249116 2019
36
Churg-strauss syndrome: clinical case and its feautures. 61
31055564 2019
37
Ophthalmic Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss Syndrome): A Systematic Review of the Literature. 61
30134390 2019
38
Necrotizing Sarcoid Granulomatosis with Pneumothorax. 61
31275399 2019
39
Eosinophilic Granulomatosis with Polyangiitis Manifesting as Recurrent Nasal Polyps and Hemorrhagic Necrotic Bullae: A Rare Disease Successfully Treated with Azathioprine. 61
31043937 2019
40
Churg-Strauss Syndrome Presenting as Acute Necrotizing Eosinophilic Myocarditis: Concise Review of the Literature. 61
30179138 2019
41
Differential Diagnosis of Churg-Strauss Syndrome with Tingling Sensation and Weakness of the Lower Extremities. 61
30719419 2018
42
Histopathological Findings and Increased D-Dimer Are Predictive Factors of Systemic Thromboses in Eosinophilic Granulomatosis With Polyangiitis. 61
29979194 2018
43
[Vasculitides and eosinophilic pulmonary diseases]. 61
30367242 2018
44
Perinuclear antineutrophil cytoplasmic antibody-associated pulmonary vasculitis masquerading as lung metastasis. 61
31397366 2018
45
[Hypokinetic cardiac arrest and hypereosinophilia: a case of Kounis or Churg-Strauss syndrome?] 61
30425395 2018
46
Coronary artery vasospasm in a patient with Churg-Strauss syndrome. 61
30366890 2018
47
Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome) masquerading as acute ST-elevation myocardial infarction with complete resolution after immunosuppressive therapy: a case report. 61
31020153 2018
48
[Vasculitides and eosinophilic pulmonary diseases]. 61
30140942 2018
49
Successful treatment outcomes in pregnant patients with ANCA-associated vasculitides: A systematic review of literature. 61
30345645 2018
50
Eosinophilic Granulomatosis with Polyangiitis: Clinical Pathology Conference and Review. 61
30197069 2018
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Variations for Allergic Angiitis

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Expression for Allergic Angiitis

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Search GEO for disease gene expression data for Allergic Angiitis.
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Pathways for Allergic Angiitis

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GO Terms for Allergic Angiitis

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Sources for Allergic Angiitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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