ABPA
MCID: ALL008
MIFTS: 56

Allergic Bronchopulmonary Aspergillosis (ABPA)

Categories: Genetic diseases, Immune diseases, Infectious diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Allergic Bronchopulmonary Aspergillosis

MalaCards integrated aliases for Allergic Bronchopulmonary Aspergillosis:

Name: Allergic Bronchopulmonary Aspergillosis 12 76 53 15
Aspergillosis, Allergic Bronchopulmonary 53 44 73
Allergic Bronchopulmonary Mycosis 53 73
Aspergillosis Allergic Bronchopulmonary 55
Pulmonary Aspergillus Disease 12
Hinson-Pepys Disease 53
Abpa 53

Classifications:



Summaries for Allergic Bronchopulmonary Aspergillosis

NIH Rare Diseases : 53 Allergic bronchopulmonary aspergillosis is an allergic lung reaction to a type of fungus (Aspergillus fumigatus). Symptoms vary, but may include wheezing, bronchial hyperreactivity, hemoptysis, productive cough, low-grade fever, malaise, and weight loss. It is more common in people who have asthma or cystic fibrosis. The recommended treatment for allergic bronchopulmonary aspergillosis is itraconazole, a prescription antifungal medication. Oral corticosteroids, like prednisone, may also be helpful. The clinical course of allergic bronchopulmonary aspergillosis is variable. Many people with this condition can be stabilized for long periods when treated. However, only about 50% of patients achieve long-lasting remission and many require recurrent courses of treatment.

MalaCards based summary : Allergic Bronchopulmonary Aspergillosis, also known as aspergillosis, allergic bronchopulmonary, is related to aspergillosis and cystic fibrosis. An important gene associated with Allergic Bronchopulmonary Aspergillosis is IL4 (Interleukin 4), and among its related pathways/superpathways are Bacterial infections in CF airways and Immune response IFN gamma signaling pathway. The drugs Itraconazole and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include lung, colon and testes, and related phenotypes are respiratory insufficiency and emphysema

Disease Ontology : 12 An aspergillosis that involves an allergic reaction due to the spores of Aspergillus moulds (A. fumigatus), which colonizes the mucus in the airways causing inflammation. The disease has symptom cough, has symptom wheezing and has symptom fever.

Wikipedia : 76 Allergic bronchopulmonary aspergillosis (ABPA) is a condition characterised by an exaggerated response... more...

Related Diseases for Allergic Bronchopulmonary Aspergillosis

Diseases in the Allergic Bronchopulmonary Aspergillosis family:

Allergic Bronchopulmonary Aspergillosis, Familial

Diseases related to Allergic Bronchopulmonary Aspergillosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 119)
# Related Disease Score Top Affiliating Genes
1 aspergillosis 32.4 CCL17 CFTR IL4 IL5 MBL2 SFTPA2
2 cystic fibrosis 31.4 CFTR MBL2 SFTPD
3 sinusitis 31.1 CFTR IL5
4 asthma 30.9 CCL17 CFTR EPX IL4 IL5
5 pneumonia 30.5 IL5 MBL2 SFTPD
6 churg-strauss syndrome 30.5 CCL17 IL5
7 rhinitis 30.5 EPX IL4 IL5
8 cough variant asthma 30.4 IL4 IL5
9 gastroenteritis 30.4 IL4 IL5
10 dermatitis 30.4 CCL17 IL4 IL5
11 allergic rhinitis 30.3 EPX IL4 IL5
12 eosinophilic gastroenteritis 30.3 EPX IL5
13 dermatitis, atopic 30.1 CCL17 EPX IL4 IL5
14 invasive aspergillosis 30.1 MBL2 SFTPD
15 eosinophilic pneumonia 30.0 CCL17 IL5 SFTPD
16 lung disease 29.9 CFTR IL5 MBL2 SFTPA2 SFTPD
17 hypereosinophilic syndrome 29.9 CCL17 EPX IL4 IL5
18 pulmonary eosinophilia 29.5 CCL17 EPX IL4 IL5 SFTPD
19 allergic bronchopulmonary aspergillosis, familial 12.6
20 plastic bronchitis 11.4
21 bronchiectasis 10.6
22 pulmonary tuberculosis 10.5
23 middle lobe syndrome 10.4
24 granulomatosis with polyangiitis 10.3
25 pneumothorax 10.3
26 eosinophilic granulomatosis with polyangiitis 10.3
27 rheumatoid arthritis 10.2
28 pulmonary disease, chronic obstructive 10.2
29 pulmonary hypertension 10.2
30 arthritis 10.2
31 pulmonary aspergilloma 10.2
32 lung abscess 10.2
33 endocarditis 10.2
34 allergic angiitis 10.2
35 nickel allergic contact dermatitis 10.2 IL4 IL5
36 scleritis 10.2 IL4 IL5
37 egg allergy 10.2 IL4 IL5
38 sulfamethoxazole allergy 10.2 IL4 IL5
39 atopic keratoconjunctivitis 10.2 IL4 IL5
40 gaucher disease, type ii 10.2 IL4 IL5
41 angiostrongyliasis 10.2 IL4 IL5
42 intrinsic asthma 10.2 IL4 IL5
43 trichinosis 10.2 IL4 IL5
44 non-suppurative otitis media 10.2 IL4 IL5
45 latex allergy 10.2 IL4 IL5
46 eosinophilic meningitis 10.2 IL4 IL5
47 vulvovaginal candidiasis 10.2 IL4 MBL2
48 intestinal schistosomiasis 10.2 IL4 IL5
49 chronic tic disorder 10.2 IL4 IL5
50 filarial elephantiasis 10.2 IL4 IL5

Graphical network of the top 20 diseases related to Allergic Bronchopulmonary Aspergillosis:



Diseases related to Allergic Bronchopulmonary Aspergillosis

Symptoms & Phenotypes for Allergic Bronchopulmonary Aspergillosis

Human phenotypes related to Allergic Bronchopulmonary Aspergillosis:

32 (show all 12)
# Description HPO Frequency HPO Source Accession
1 respiratory insufficiency 32 occasional (7.5%) HP:0002093
2 emphysema 32 occasional (7.5%) HP:0002097
3 pulmonary arterial hypertension 32 occasional (7.5%) HP:0002092
4 weight loss 32 frequent (33%) HP:0001824
5 abnormality of the fingernails 32 occasional (7.5%) HP:0001231
6 cerebral cortical atrophy 32 frequent (33%) HP:0002120
7 hemoptysis 32 occasional (7.5%) HP:0002105
8 asthma 32 hallmark (90%) HP:0002099
9 cough 32 hallmark (90%) HP:0012735
10 bronchiectasis 32 frequent (33%) HP:0002110
11 low-grade fever 32 frequent (33%) HP:0011134
12 abnormal eosinophil morphology 32 hallmark (90%) HP:0001879

MGI Mouse Phenotypes related to Allergic Bronchopulmonary Aspergillosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.5 CCL17 CFTR EPX IL4 IL5 MBL2
2 immune system MP:0005387 9.17 CCL17 CFTR EPX IL4 IL5 MBL2

Drugs & Therapeutics for Allergic Bronchopulmonary Aspergillosis

Drugs for Allergic Bronchopulmonary Aspergillosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 66)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Itraconazole Approved, Investigational Phase 4,Phase 2,Phase 3 84625-61-6 55283
2
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 22916-47-8 4189
3
Omalizumab Approved, Investigational Phase 4 242138-07-4
4 Respiratory System Agents Phase 4,Phase 2,Phase 3
5 Hormone Antagonists Phase 4,Phase 2,Phase 3
6 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3
7 Steroid Synthesis Inhibitors Phase 4,Phase 2,Phase 3
8 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 2,Phase 3
9 Antibodies Phase 4
10
Hydroxyitraconazole Phase 4,Phase 2,Phase 3
11 Anti-Allergic Agents Phase 4,Phase 2,Phase 3
12 Immunoglobulin E Phase 4
13 Hormones Phase 4,Phase 2,Phase 3
14 Anti-Asthmatic Agents Phase 4,Phase 2,Phase 3
15 Antifungal Agents Phase 4,Phase 2,Phase 3
16 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 2,Phase 3
17 Anti-Infective Agents Phase 4,Phase 2,Phase 3
18 Immunoglobulins Phase 4
19
Prednisolone Approved, Vet_approved Phase 2, Phase 3,Phase 3 50-24-8 5755
20
Methylprednisolone hemisuccinate Approved Phase 2, Phase 3,Phase 3 2921-57-5
21
Prednisolone phosphate Approved, Vet_approved Phase 2, Phase 3,Phase 3 302-25-0
22
Methylprednisolone Approved, Vet_approved Phase 2, Phase 3,Phase 3 83-43-2 6741
23
Voriconazole Approved, Investigational Phase 2, Phase 3 137234-62-9 71616
24
Fluticasone Approved, Experimental Phase 2, Phase 3,Phase 3 90566-53-3 62924
25
Budesonide Approved Phase 2, Phase 3 51333-22-3 63006 5281004
26
deoxycholic acid Approved Phase 2, Phase 3 83-44-3 222528
27
Amphotericin B Approved, Investigational Phase 2, Phase 3 1397-89-3 5280965 14956
28
Ergocalciferol Approved, Nutraceutical Phase 2, Phase 3,Not Applicable 50-14-6 5280793
29
Vitamin D3 Approved, Nutraceutical Phase 2, Phase 3,Phase 3,Not Applicable 67-97-0 5280795 6221
30
Vitamin D Approved, Nutraceutical, Vet_approved Phase 2, Phase 3,Not Applicable 1406-16-2
31
Prednisolone hemisuccinate Experimental Phase 2, Phase 3,Phase 3 2920-86-7
32 glucocorticoids Phase 2, Phase 3,Phase 3
33 Methylprednisolone acetate Phase 2, Phase 3,Phase 3
34 Prednisolone acetate Phase 2, Phase 3,Phase 3
35 Formoterol Fumarate Phase 2, Phase 3,Phase 3
36 Autonomic Agents Phase 2, Phase 3,Phase 3
37 Antineoplastic Agents, Hormonal Phase 2, Phase 3,Phase 3
38 Peripheral Nervous System Agents Phase 2, Phase 3,Phase 3
39 Neuroprotective Agents Phase 2, Phase 3,Phase 3
40 Gastrointestinal Agents Phase 2, Phase 3,Phase 3
41 Protective Agents Phase 2, Phase 3,Phase 3
42 Anti-Inflammatory Agents Phase 2, Phase 3,Phase 3
43 Antiemetics Phase 2, Phase 3,Phase 3
44 Calciferol Phase 2, Phase 3,Not Applicable
45 Ergocalciferols Phase 2, Phase 3,Not Applicable
46 Micronutrients Phase 2, Phase 3,Not Applicable
47 Bone Density Conservation Agents Phase 2, Phase 3,Not Applicable
48 Vitamins Phase 2, Phase 3,Not Applicable
49 Vitamin D2 Phase 2, Phase 3,Not Applicable
50 Trace Elements Phase 2, Phase 3,Not Applicable

Interventional clinical trials:

(show all 23)
# Name Status NCT ID Phase Drugs
1 An Exploratory Study to Assess Multiple Doses of Omalizumab in Patients With Cystic Fibrosis Complicated by Acute Bronchopulmonary Aspergillosis (ABPA) Terminated NCT00787917 Phase 4 Omalizumab;Placebo;Itraconazole
2 Trial on the Efficacy and Safety of Two Different Glucocorticoid Dose Regimens in Allergic Bronchopulmonary Aspergillosis Completed NCT00974766 Phase 2, Phase 3 Glucocorticoids;Glucocorticoids
3 Voriconazole Versus Oral Steroids in Allergic Bronchopulmonary Aspergillosis Completed NCT01621321 Phase 2, Phase 3 Prednisolone;Voriconazole
4 A Study Evaluating Vitamin D in Allergic Bronchopulmonary Aspergillosis Complicating Asthma Completed NCT03133299 Phase 2, Phase 3 Glucocorticoids;Vitamin D
5 A Randomized Controlled Trial of Inhaled Amphotericin B for Maintaining Remission in Allergic Bronchopulmonary Aspergillosis Completed NCT01857479 Phase 2, Phase 3 Inhaled budesonide;Inhaled amphotericin
6 Monotherapy of Itraconazole Versus Prednisolone in Allergic Bronchopulmonary Aspergillosis Completed NCT01321827 Phase 2, Phase 3 Glucocorticoids;Itraconazole
7 A Randomized Trial of Itraconazole in Acute Stages of Allergic Bronchopulmonary Aspergillosis Recruiting NCT02440009 Phase 2, Phase 3 Itraconazole;Glucocorticoids
8 Evaluation of a Therapeutic Strategy Including Nebulised Liposomal Amphotericin B (Ambisome®) in Maintenance Treatment of Allergic Bronchopulmonary Aspergillosis (Cystic Fibrosis Excluded). Active, not recruiting NCT02273661 Phase 2 Liposomal amphotericin B (Ambisome®);placebo
9 Safety, Tolerability, Pharmacokinetics, and Preliminary Pharmacodynamics of QBW251 in Healthy Subjects and Cystic Fibrosis Patients Terminated NCT02190604 Phase 1, Phase 2 Placebo;QBW251
10 Lung MRI and Allergic Broncho-pulmonary Aspergillosis in Cystic Fibrosis Completed NCT02853175
11 Mechanisms of Immune Tolerance and Inflammation in Patients With Cystic Fibrosis With ABPA Completed NCT00585364
12 Protocol TARC-ABPA Completed NCT01710930 Not Applicable
13 Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis Completed NCT01222273 Not Applicable
14 Evaluation of Bronchial Inflammation in Allergic Bronchopulmonary Aspergillosis (ABPA) Completed NCT00906568
15 Duplication in CHIT1 Gene and the Risk for Aspergillus Lung Disease in CF Patients Completed NCT01572870
16 Estimated Impact of Fungal Colonization in Cystic Fibrosis From Secondary Exploitation of MucoFong Database. Completed NCT03753828
17 Cytokine Profile of Allergic Bronchopulmonary Aspergillosis Recruiting NCT03643185
18 Natural History of Bronchiectasis Recruiting NCT00943514
19 Observational Study of Characteristics, Treatment and Outcomes With Severe Asthma in the United States (CHRONICLE) Recruiting NCT03373045
20 MR Imaging of Lung in the Follow-up Assessment of Cystic Fibrosis Recruiting NCT03357562 Not Applicable
21 Diagnostic Value of MRI for Allergic Broncho-Pulmonary Aspergilloses Not yet recruiting NCT03265366 Not Applicable
22 Role of Thymus-And Activation-Regulated Chemokine (TARC) In Diagnosis Of Allergic Bronchopulmonary Aspergillosis Not yet recruiting NCT03267394
23 Analysis T Cells Response for Identification of Aspergillus Bronchitis With Cystic Fibrosis Patients Terminated NCT02550041 Not Applicable

Search NIH Clinical Center for Allergic Bronchopulmonary Aspergillosis

Cochrane evidence based reviews: aspergillosis, allergic bronchopulmonary

Genetic Tests for Allergic Bronchopulmonary Aspergillosis

Anatomical Context for Allergic Bronchopulmonary Aspergillosis

MalaCards organs/tissues related to Allergic Bronchopulmonary Aspergillosis:

41
Lung, Colon, Testes, T Cells, Skin, Bone, Thymus

Publications for Allergic Bronchopulmonary Aspergillosis

Articles related to Allergic Bronchopulmonary Aspergillosis:

(show top 50) (show all 722)
# Title Authors Year
1
Allergic bronchopulmonary aspergillosis successfully treated with mepolizumab: Case report and review of the literature. ( 30533379 )
2019
2
"Fleeting pulmonary infiltrates in allergic bronchopulmonary aspergillosis" Misdiagnosed as tuberculosis. ( 29900899 )
2018
3
National Jewish Health Classical Pulmonary Radiology Case Reports: Imaging Features of Allergic Bronchopulmonary Aspergillosis. ( 29878247 )
2018
4
Omalizumab in allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. ( 29950869 )
2018
5
Risk Factors and impact of Allergic Bronchopulmonary Aspergillosis in P. aeruginosa negative CF Patients. ( 29981532 )
2018
6
Prevalence of sensitization to Aspergillus flavus in patients with allergic bronchopulmonary aspergillosis. ( 29566248 )
2018
7
Vitamin D levels in asthmatic patients with and without allergic bronchopulmonary aspergillosis. ( 29314357 )
2018
8
A Randomized Trial of Itraconazole vs Prednisolone in Acute-Stage Allergic Bronchopulmonary Aspergillosis Complicating Asthma. ( 29331473 )
2018
9
Clinical Characteristics of Fifty Patients with Allergic Bronchopulmonary Aspergillosis. ( 29692383 )
2018
10
Allergic bronchopulmonary aspergillosis presenting as nephrotic syndrome due to secondary amyloidosis: Case report and systematic review of the literature. ( 29970774 )
2018
11
A case of allergic bronchopulmonary aspergillosis in a 43-year-old farmer following single high level exposure to organic dust with symptomatic remission and radiological resolution after early diagnosis and treatment. ( 29479448 )
2018
12
Utility of recombinant Aspergillus fumigatus antigens in the diagnosis of allergic bronchopulmonary aspergillosis: a systematic review and diagnostic test accuracy meta-analysis. ( 29927507 )
2018
13
Anti-IgE therapy for allergic bronchopulmonary aspergillosis in people with cystic fibrosis. ( 29551015 )
2018
14
Mutations in EEA1 are associated with allergic bronchopulmonary aspergillosis and affect phagocytosis of Aspergillus fumigatus by human macrophages. ( 29547649 )
2018
15
Asthma and Fungus: Role in Allergic Bronchopulmonary Aspergillosis (ABPA) and Other Conditions. ( 29549557 )
2018
16
Severe asthma concomitant with allergic bronchopulmonary aspergillosis successfully treated with mepolizumab. ( 29665990 )
2018
17
Mycobacterium avium intracellulare infection complicated by allergic bronchopulmonary aspergillosis in a non-asthmatic patient. ( 29804082 )
2018
18
A case of allergic bronchopulmonary aspergillosis successfully treated with mepolizumab. ( 29587693 )
2018
19
Allergic bronchopulmonary aspergillosis in patients with cystic fibrosis and non-cystic fibrosis bronchiectasis. ( 29588830 )
2018
20
Concordance between Aspergillus-specific precipitating antibody and IgG in allergic bronchopulmonary aspergillosis. ( 29773475 )
2018
21
A randomised trial of voriconazole and prednisolone monotherapy in acute-stage allergic bronchopulmonary aspergillosis complicating asthma. ( 30049743 )
2018
22
Allergic Bronchopulmonary Aspergillosis. ( 30140508 )
2018
23
Radioaerosol Imaging Predicts the Utility of Aerosolized Antifungal Therapy in Allergic Bronchopulmonary Aspergillosis. ( 30199380 )
2018
24
Erratum: Omalizumab in allergic bronchopulmonary aspergillosis in patients with cystic fibrosis [Erratum]. ( 30254475 )
2018
25
Intravenous immunoglobulin protects from experimental allergic bronchopulmonary aspergillosis via a sialylation-dependent mechanism. ( 30267564 )
2018
26
Allergic Bronchopulmonary Aspergillosis-A Luminal Hypereosinophilic Disease With Extracellular Trap Cell Death. ( 30364279 )
2018
27
Childhood allergic bronchopulmonary aspergillosis. ( 30381560 )
2018
28
Pulmonary infection caused by Nocardia cyriacigeorgica in a patient with allergic bronchopulmonary aspergillosis: A case report. ( 30412142 )
2018
29
Allergic bronchopulmonary aspergillosis successfully treated with benralizumab. ( 30513359 )
2018
30
Recurrence of allergic bronchopulmonary aspergillosis after adjunctive surgery for aspergilloma: a case report with long-term follow-up. ( 30514257 )
2018
31
Omalizumab as add-on therapy in patients with asthma and allergic bronchopulmonary aspergillosis. ( 30517345 )
2018
32
Prevalence of allergic bronchopulmonary aspergillosis in asthmatic patients: A prospective institutional study. ( 30522614 )
2018
33
Voriconazole hepatotoxicity as a result of steroid withdrawal in a patient with allergic bronchopulmonary aspergillosis. ( 30537018 )
2018
34
A review of 42 asthmatic children with allergic bronchopulmonary aspergillosis. ( 28765819 )
2017
35
Allergic bronchopulmonary aspergillosis in Japan: A nationwide survey. ( 28546015 )
2017
36
Mucus plugging in allergic bronchopulmonary aspergillosis: Implication of the eosinophil DNA traps. ( 28886913 )
2017
37
Combination omalizumab and mepolizumab therapy for refractory allergic bronchopulmonary aspergillosis. ( 28279664 )
2017
38
Prevalence of Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma at a tertiary care center in North India. ( 28360463 )
2017
39
Modern challenges of allergic bronchopulmonary aspergillosis diagnosis and management: Finding from a case study with a history of rituximab use. ( 28668248 )
2017
40
Two cases of non-cystic fibrosis (CF) bronchiectasis with allergic bronchopulmonary aspergillosis. ( 28053855 )
2017
41
Inverted Mucoid Impaction Signal in Allergic Bronchopulmonary Aspergillosis: Are We Calling a Spade a Big Spoon? ( 29045221 )
2017
42
Effect of allergic bronchopulmonary aspergillosis on FEV1 in children and adolescents with cystic fibrosis: a European Cystic Fibrosis Society Patient Registry analysis. ( 28325727 )
2017
43
Identifying rare diseases using electronic medical records: the example of allergic bronchopulmonary aspergillosis. ( 28370596 )
2017
44
Case series of omalizumab for allergic bronchopulmonary aspergillosis in cystic fibrosis patients. ( 27717223 )
2017
45
F508del CFTR gene mutation in patients with allergic bronchopulmonary aspergillosis. ( 29035608 )
2017
46
Omalizumab treatment for allergic bronchopulmonary aspergillosis in young patients with cystic fibrosis. ( 29173443 )
2017
47
Beneficial effects of Omalizumab therapy in allergic bronchopulmonary aspergillosis: A synthesis review of published literature. ( 27993289 )
2017
48
Allergic bronchopulmonary aspergillosis causing bendopnea. ( 28474666 )
2017
49
Diagnosis of Allergic Bronchopulmonary Aspergillosis Exacerbations. ( 29122158 )
2017
50
Allergic bronchopulmonary aspergillosis treated successfully with omalizumab. ( 28705584 )
2017

Variations for Allergic Bronchopulmonary Aspergillosis

Expression for Allergic Bronchopulmonary Aspergillosis

Search GEO for disease gene expression data for Allergic Bronchopulmonary Aspergillosis.

Pathways for Allergic Bronchopulmonary Aspergillosis

Pathways related to Allergic Bronchopulmonary Aspergillosis according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.76 CFTR IL4 SFTPD
2
Show member pathways
11.74 CCL17 IL4 IL5
3 11.68 MBL2 SFTPA2 SFTPD
4
Show member pathways
11.59 CCL17 CFTR IL4 IL5
5 11.23 CCL17 IL4 IL5
6
Show member pathways
11.2 SFTPA2 SFTPD
7
Show member pathways
11.16 SFTPA2 SFTPD
8 11.13 IL4 IL5 SFTPA2
9 11.03 IL4 IL5
10 11 IL4 IL5
11 10.94 IL4 IL5
12 10.87 IL4 IL5
13
Show member pathways
10.83 SFTPA2 SFTPD
14 10.81 CCL17 IL4 IL5
15 10.46 CCL17 IL4 IL5

GO Terms for Allergic Bronchopulmonary Aspergillosis

Cellular components related to Allergic Bronchopulmonary Aspergillosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 CCL17 EPX IL4 IL5 MBL2 SFTPA2
2 collagen trimer GO:0005581 9.33 MBL2 SFTPA2 SFTPD
3 multivesicular body GO:0005771 9.32 SFTPA2 SFTPD
4 clathrin-coated endocytic vesicle GO:0045334 9.26 SFTPA2 SFTPD
5 extracellular space GO:0005615 9.17 CCL17 EPX IL4 IL5 MBL2 SFTPA2

Biological processes related to Allergic Bronchopulmonary Aspergillosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.43 EPX MBL2 SFTPD
2 positive regulation of B cell proliferation GO:0030890 9.37 IL4 IL5
3 toll-like receptor signaling pathway GO:0002224 9.32 SFTPA2 SFTPD
4 respiratory gaseous exchange GO:0007585 9.16 SFTPA2 SFTPD
5 surfactant homeostasis GO:0043129 8.96 SFTPA2 SFTPD
6 positive regulation of phagocytosis GO:0050766 8.8 MBL2 SFTPA2 SFTPD

Molecular functions related to Allergic Bronchopulmonary Aspergillosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 carbohydrate binding GO:0030246 9.33 MBL2 SFTPA2 SFTPD
2 lipopolysaccharide binding GO:0001530 9.26 SFTPA2 SFTPD
3 cytokine activity GO:0005125 9.13 CCL17 IL4 IL5
4 monosaccharide binding GO:0048029 8.62 SFTPA2 SFTPD

Sources for Allergic Bronchopulmonary Aspergillosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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