MCID: ALL008
MIFTS: 57

Allergic Bronchopulmonary Aspergillosis

Categories: Rare diseases, Infectious diseases, Bone diseases, Cardiovascular diseases, Respiratory diseases, Nephrological diseases, Eye diseases, Gastrointestinal diseases, Neuronal diseases, Immune diseases, Genetic diseases

Aliases & Classifications for Allergic Bronchopulmonary Aspergillosis

MalaCards integrated aliases for Allergic Bronchopulmonary Aspergillosis:

Name: Allergic Bronchopulmonary Aspergillosis 12 76 53 15
Aspergillosis, Allergic Bronchopulmonary 53 44 73
Allergic Bronchopulmonary Mycosis 53 73
Aspergillosis Allergic Bronchopulmonary 55
Pulmonary Aspergillus Disease 12
Hinson-Pepys Disease 53
Abpa 53

Classifications:



Summaries for Allergic Bronchopulmonary Aspergillosis

NIH Rare Diseases : 53 Allergic bronchopulmonary aspergillosis is an allergic lung reaction to a type of fungus (Aspergillus fumigatus). Symptoms vary, but may include wheezing, bronchial hyperreactivity, hemoptysis, productive cough, low-grade fever, malaise, and weight loss. It is more common in people who have asthma or cystic fibrosis. The recommended treatment for allergic bronchopulmonary aspergillosis is itraconazole, a prescription antifungal medication. Oral corticosteroids, like prednisone, may also be helpful. The clinical course of allergic bronchopulmonary aspergillosis is variable. Many people with this condition can be stabilized for long periods when treated. However, only about 50% of patients achieve long-lasting remission and many require recurrent courses of treatment.

MalaCards based summary : Allergic Bronchopulmonary Aspergillosis, also known as aspergillosis, allergic bronchopulmonary, is related to sinusitis and cough variant asthma, and has symptoms including cough, wheezing and fever. An important gene associated with Allergic Bronchopulmonary Aspergillosis is IL4 (Interleukin 4), and among its related pathways/superpathways are Bacterial infections in CF airways and Phagosome. The drugs Itraconazole and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include lung, colon and testes, and related phenotypes are abnormality of the fingernails and weight loss

Disease Ontology : 12 An aspergillosis that involves an allergic reaction due to the spores of Aspergillus moulds (A. fumigatus), which colonizes the mucus in the airways causing inflammation. The disease has symptom cough, has symptom wheezing and has symptom fever.

Wikipedia : 76 Allergic bronchopulmonary aspergillosis (ABPA) is a condition characterised by an exaggerated response... more...

Related Diseases for Allergic Bronchopulmonary Aspergillosis

Diseases in the Allergic Bronchopulmonary Aspergillosis family:

Allergic Bronchopulmonary Aspergillosis, Familial

Diseases related to Allergic Bronchopulmonary Aspergillosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 111)
# Related Disease Score Top Affiliating Genes
1 sinusitis 31.2 CFTR IL5
2 cough variant asthma 30.9 IL4 IL5
3 churg-strauss syndrome 30.6 CCL17 IL5
4 eosinophilic gastroenteritis 30.5 EPX IL5
5 rhinitis 30.3 EPX IL4 IL5
6 pneumonia 30.3 IL5 MBL2 SFTPD
7 dermatitis 30.3 CCL17 IL4 IL5
8 cystic fibrosis 30.3 CCL17 CFTR MBL2 SFTPD
9 gastroenteritis 30.2 IL4 IL5
10 allergic rhinitis 30.2 EPX IL4 IL5
11 aspergillosis 30.0 CCL17 CFTR IL4 IL5 MBL2 SFTPA2
12 eosinophilic pneumonia 29.6 CCL17 IL5 SFTPD
13 asthma 29.5 CCL17 CFTR EPX IL4 IL5
14 dermatitis, atopic 29.4 CCL17 EPX IL4 IL5
15 lung disease 29.1 CFTR IL5 SFTPA2 SFTPD
16 pulmonary eosinophilia 28.1 CCL17 EPX IL4 IL5 SFTPD
17 allergic bronchopulmonary aspergillosis, familial 12.5
18 plastic bronchitis 11.3
19 egg allergy 10.6 IL4 IL5
20 scleritis 10.6 IL4 IL5
21 intrinsic asthma 10.6 IL4 IL5
22 atopic keratoconjunctivitis 10.6 IL4 IL5
23 angiostrongyliasis 10.6 IL4 IL5
24 trichinosis 10.6 IL4 IL5
25 non-suppurative otitis media 10.6 IL4 IL5
26 latex allergy 10.6 IL4 IL5
27 eosinophilic meningitis 10.6 IL4 IL5
28 cercarial dermatitis 10.6 IL4 IL5
29 intestinal schistosomiasis 10.6 IL4 IL5
30 gastrointestinal allergy 10.6 IL4 IL5
31 chronic conjunctivitis 10.6 IL4 IL5
32 eosinophilic gastritis 10.6 IL4 IL5
33 kimura disease 10.6 IL4 IL5
34 vulvovaginal candidiasis 10.6 IL4 MBL2
35 chronic tic disorder 10.6 IL4 IL5
36 folliculitis 10.6 IL4 IL5
37 vernal keratoconjunctivitis 10.6 IL4 IL5
38 toxic oil syndrome 10.6 IL4 IL5
39 primary amebic meningoencephalitis 10.6 IL4 IL5
40 cryptococcosis 10.5 IL4 MBL2
41 conjunctival disease 10.5 IL4 IL5
42 enterobiasis 10.5 IL4 IL5
43 milk allergy 10.5 IL4 IL5
44 necatoriasis 10.5 CCL17 IL5
45 paragonimiasis 10.5 CCL17 IL5
46 rheumatic heart disease 10.5 IL4 MBL2
47 paranasal sinus disease 10.5 IL4 IL5
48 bronchiectasis 10.4
49 allergic conjunctivitis 10.4 IL4 IL5
50 nasal cavity disease 10.4 IL4 IL5

Graphical network of the top 20 diseases related to Allergic Bronchopulmonary Aspergillosis:



Diseases related to Allergic Bronchopulmonary Aspergillosis

Symptoms & Phenotypes for Allergic Bronchopulmonary Aspergillosis

Symptoms:

12
  • cough
  • wheezing
  • fever

Human phenotypes related to Allergic Bronchopulmonary Aspergillosis:

32 (show all 12)
# Description HPO Frequency HPO Source Accession
1 abnormality of the fingernails 32 occasional (7.5%) HP:0001231
2 weight loss 32 frequent (33%) HP:0001824
3 abnormal eosinophil morphology 32 hallmark (90%) HP:0001879
4 pulmonary arterial hypertension 32 occasional (7.5%) HP:0002092
5 respiratory insufficiency 32 occasional (7.5%) HP:0002093
6 emphysema 32 occasional (7.5%) HP:0002097
7 asthma 32 hallmark (90%) HP:0002099
8 hemoptysis 32 occasional (7.5%) HP:0002105
9 bronchiectasis 32 frequent (33%) HP:0002110
10 cerebral cortical atrophy 32 frequent (33%) HP:0002120
11 low-grade fever 32 frequent (33%) HP:0011134
12 cough 32 hallmark (90%) HP:0012735

MGI Mouse Phenotypes related to Allergic Bronchopulmonary Aspergillosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.5 IL5 MBL2 SFTPD CCL17 CFTR EPX
2 immune system MP:0005387 9.17 IL5 MBL2 SFTPD CCL17 CFTR EPX

Drugs & Therapeutics for Allergic Bronchopulmonary Aspergillosis

Drugs for Allergic Bronchopulmonary Aspergillosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 65)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Itraconazole Approved, Investigational Phase 4,Phase 2,Phase 3 84625-61-6 55283
2
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 22916-47-8 4189
3
Omalizumab Approved, Investigational Phase 4 242138-07-4
4 Anti-Allergic Agents Phase 4,Phase 2,Phase 3
5 Anti-Asthmatic Agents Phase 4,Phase 2,Phase 3
6 Antibodies Phase 4
7 Antifungal Agents Phase 4,Phase 2,Phase 3
8 Anti-Infective Agents Phase 4,Phase 2,Phase 3
9 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 2,Phase 3
10 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 2,Phase 3
11 Hormone Antagonists Phase 4,Phase 2,Phase 3
12 Hormones Phase 4,Phase 2,Phase 3
13 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3
14
Hydroxyitraconazole Phase 4,Phase 2,Phase 3
15 Immunoglobulin E Phase 4
16 Immunoglobulins Phase 4
17 Respiratory System Agents Phase 4,Phase 2,Phase 3
18 Steroid Synthesis Inhibitors Phase 4,Phase 2,Phase 3
19
Methylprednisolone Approved, Vet_approved Phase 2, Phase 3,Phase 3 83-43-2 6741
20
Prednisolone Approved, Vet_approved Phase 2, Phase 3,Phase 3 50-24-8 5755
21
Fluticasone Approved, Experimental, Investigational Phase 2, Phase 3,Phase 3 90566-53-3 62924
22
Voriconazole Approved, Investigational Phase 2, Phase 3 137234-62-9 71616
23
Amphotericin B Approved, Investigational Phase 2, Phase 3 1397-89-3 14956 5280965
24
Budesonide Approved Phase 2, Phase 3 51333-22-3 63006 5281004
25
deoxycholic acid Approved Phase 2, Phase 3 83-44-3 222528
26
Ergocalciferol Approved, Nutraceutical Phase 2, Phase 3,Not Applicable 50-14-6 5280793
27
Vitamin D Approved, Nutraceutical, Vet_approved Phase 2, Phase 3,Not Applicable 1406-16-2
28
Vitamin D3 Approved, Nutraceutical Phase 2, Phase 3,Phase 3,Not Applicable 67-97-0 6221 5280795
29 glucocorticoids Phase 2, Phase 3,Phase 3
30 Methylprednisolone acetate Phase 2, Phase 3,Phase 3
31 Methylprednisolone Hemisuccinate Phase 2, Phase 3,Phase 3
32 Prednisolone acetate Phase 2, Phase 3,Phase 3
33 Prednisolone hemisuccinate Phase 2, Phase 3,Phase 3
34 Prednisolone phosphate Phase 2, Phase 3,Phase 3
35 Antiemetics Phase 2, Phase 3,Phase 3
36 Anti-Inflammatory Agents Phase 2, Phase 3,Phase 3
37 Antineoplastic Agents, Hormonal Phase 2, Phase 3,Phase 3
38 Autonomic Agents Phase 2, Phase 3,Phase 3
39 Formoterol Fumarate Phase 2, Phase 3,Phase 3
40 Gastrointestinal Agents Phase 2, Phase 3,Phase 3
41 Neuroprotective Agents Phase 2, Phase 3,Phase 3
42 Peripheral Nervous System Agents Phase 2, Phase 3,Phase 3
43 Protective Agents Phase 2, Phase 3,Phase 3
44 Adrenergic Agents Phase 2, Phase 3,Phase 3
45 Adrenergic Agonists Phase 2, Phase 3,Phase 3
46 Adrenergic beta-2 Receptor Agonists Phase 2, Phase 3,Phase 3
47 Adrenergic beta-Agonists Phase 2, Phase 3,Phase 3
48 Amphotericin B, deoxycholate drug combination Phase 2, Phase 3
49 Anti-Bacterial Agents Phase 2, Phase 3
50 Antiparasitic Agents Phase 2, Phase 3

Interventional clinical trials:

(show all 21)
# Name Status NCT ID Phase Drugs
1 An Exploratory Study to Assess Multiple Doses of Omalizumab in Patients With Cystic Fibrosis Complicated by Acute Bronchopulmonary Aspergillosis (ABPA) Terminated NCT00787917 Phase 4 Omalizumab;Placebo;Itraconazole
2 Trial on the Efficacy and Safety of Two Different Glucocorticoid Dose Regimens in Allergic Bronchopulmonary Aspergillosis Completed NCT00974766 Phase 2, Phase 3 Glucocorticoids;Glucocorticoids
3 Voriconazole Versus Oral Steroids in Allergic Bronchopulmonary Aspergillosis Completed NCT01621321 Phase 2, Phase 3 Prednisolone;Voriconazole
4 A Randomized Controlled Trial of Inhaled Amphotericin B for Maintaining Remission in Allergic Bronchopulmonary Aspergillosis Completed NCT01857479 Phase 2, Phase 3 Inhaled budesonide;Inhaled amphotericin
5 Monotherapy of Itraconazole Versus Prednisolone in Allergic Bronchopulmonary Aspergillosis Completed NCT01321827 Phase 2, Phase 3 Glucocorticoids;Itraconazole
6 A Randomized Trial of Itraconazole in Acute Stages of Allergic Bronchopulmonary Aspergillosis Recruiting NCT02440009 Phase 2, Phase 3 Itraconazole;Glucocorticoids
7 A Study Evaluating Vitamin D in Allergic Bronchopulmonary Aspergillosis Complicating Asthma Not yet recruiting NCT03133299 Phase 2, Phase 3 Glucocorticoids;Vitamin D
8 Evaluation of a Therapeutic Strategy Including Nebulised Liposomal Amphotericin B (Ambisome®) in Maintenance Treatment of Allergic Bronchopulmonary Aspergillosis (Cystic Fibrosis Excluded). Active, not recruiting NCT02273661 Phase 2 Liposomal amphotericin B (Ambisome®);placebo
9 Safety, Tolerability, Pharmacokinetics, and Preliminary Pharmacodynamics of QBW251 in Healthy Subjects and Cystic Fibrosis Patients Terminated NCT02190604 Phase 1, Phase 2 Placebo;QBW251
10 Lung MRI and Allergic Broncho-pulmonary Aspergillosis in Cystic Fibrosis Completed NCT02853175
11 Mechanisms of Immune Tolerance and Inflammation in Patients With Cystic Fibrosis With ABPA Completed NCT00585364
12 Protocol TARC-ABPA Completed NCT01710930 Not Applicable
13 Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis Completed NCT01222273 Not Applicable
14 Evaluation of Bronchial Inflammation in Allergic Bronchopulmonary Aspergillosis (ABPA) Completed NCT00906568
15 Duplication in CHIT1 Gene and the Risk for Aspergillus Lung Disease in CF Patients Completed NCT01572870
16 Natural History of Bronchiectasis Recruiting NCT00943514
17 Observational Study of Characteristics, Treatment and Outcomes With Severe Asthma in the United States (CHRONICLE) Recruiting NCT03373045
18 MR Imaging of Lung in the Follow-up Assessment of Cystic Fibrosis Recruiting NCT03357562 Not Applicable
19 Diagnostic Value of MRI for Allergic Broncho-Pulmonary Aspergilloses Not yet recruiting NCT03265366 Not Applicable
20 Role of Thymus-And Activation-Regulated Chemokine (TARC) In Diagnosis Of Allergic Bronchopulmonary Aspergillosis Not yet recruiting NCT03267394
21 Analysis T Cells Response for Identification of Aspergillus Bronchitis With Cystic Fibrosis Patients Terminated NCT02550041 Not Applicable

Search NIH Clinical Center for Allergic Bronchopulmonary Aspergillosis

Cochrane evidence based reviews: aspergillosis, allergic bronchopulmonary

Genetic Tests for Allergic Bronchopulmonary Aspergillosis

Anatomical Context for Allergic Bronchopulmonary Aspergillosis

MalaCards organs/tissues related to Allergic Bronchopulmonary Aspergillosis:

41
Lung, Colon, Testes, T Cells, Bone, Skin, Eye

Publications for Allergic Bronchopulmonary Aspergillosis

Articles related to Allergic Bronchopulmonary Aspergillosis:

(show top 50) (show all 631)
# Title Authors Year
1
National Jewish Health Classical Pulmonary Radiology Case Reports: Imaging Features of Allergic Bronchopulmonary Aspergillosis. ( 29878247 )
2018
2
Omalizumab in allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. ( 29950869 )
2018
3
Risk Factors and impact of Allergic Bronchopulmonary Aspergillosis in P. aeruginosa negative CF Patients. ( 29981532 )
2018
4
Prevalence of sensitization to Aspergillus flavus in patients with allergic bronchopulmonary aspergillosis. ( 29566248 )
2018
5
Vitamin D levels in asthmatic patients with and without allergic bronchopulmonary aspergillosis. ( 29314357 )
2018
6
A Randomized Trial of Itraconazole vs Prednisolone in Acute-Stage Allergic Bronchopulmonary Aspergillosis Complicating Asthma. ( 29331473 )
2018
7
Clinical Characteristics of Fifty Patients with Allergic Bronchopulmonary Aspergillosis. ( 29692383 )
2018
8
Allergic bronchopulmonary aspergillosis presenting as nephrotic syndrome due to secondary amyloidosis: Case report and systematic review of the literature. ( 29970774 )
2018
9
A case of allergic bronchopulmonary aspergillosis in a 43-year-old farmer following single high level exposure to organic dust with symptomatic remission and radiological resolution after early diagnosis and treatment. ( 29479448 )
2018
10
Utility of recombinant Aspergillus fumigatus antigens in the diagnosis of allergic bronchopulmonary aspergillosis: a systematic review and diagnostic test accuracy meta-analysis. ( 29927507 )
2018
11
Anti-IgE therapy for allergic bronchopulmonary aspergillosis in people with cystic fibrosis. ( 29551015 )
2018
12
Mutations in EEA1 are associated with allergic bronchopulmonary aspergillosis and affect phagocytosis of Aspergillus fumigatus by human macrophages. ( 29547649 )
2018
13
Asthma and Fungus: Role in Allergic Bronchopulmonary Aspergillosis (ABPA) and Other Conditions. ( 29549557 )
2018
14
Severe asthma concomitant with allergic bronchopulmonary aspergillosis successfully treated with mepolizumab. ( 29665990 )
2018
15
Mycobacterium avium intracellulare infection complicated by allergic bronchopulmonary aspergillosis in a non-asthmatic patient. ( 29804082 )
2018
16
A case of allergic bronchopulmonary aspergillosis successfully treated with mepolizumab. ( 29587693 )
2018
17
Allergic bronchopulmonary aspergillosis in patients with cystic fibrosis and non-cystic fibrosis bronchiectasis. ( 29588830 )
2018
18
Concordance between Aspergillus-specific precipitating antibody and IgG in allergic bronchopulmonary aspergillosis. ( 29773475 )
2018
19
A review of 42 asthmatic children with allergic bronchopulmonary aspergillosis. ( 28765819 )
2017
20
Allergic bronchopulmonary aspergillosis in Japan: A nationwide survey. ( 28546015 )
2017
21
Mucus plugging in allergic bronchopulmonary aspergillosis: Implication of the eosinophil DNA traps. ( 28886913 )
2017
22
Combination omalizumab and mepolizumab therapy for refractory allergic bronchopulmonary aspergillosis. ( 28279664 )
2017
23
Prevalence of Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma at a tertiary care center in North India. ( 28360463 )
2017
24
Modern challenges of allergic bronchopulmonary aspergillosis diagnosis and management: Finding from a case study with a history of rituximab use. ( 28668248 )
2017
25
Two cases of non-cystic fibrosis (CF) bronchiectasis with allergic bronchopulmonary aspergillosis. ( 28053855 )
2017
26
Inverted Mucoid Impaction Signal in Allergic Bronchopulmonary Aspergillosis: Are We Calling a Spade a Big Spoon? ( 29045221 )
2017
27
Effect of allergic bronchopulmonary aspergillosis on FEV1 in children and adolescents with cystic fibrosis: a European Cystic Fibrosis Society Patient Registry analysis. ( 28325727 )
2017
28
Identifying rare diseases using electronic medical records: the example of allergic bronchopulmonary aspergillosis. ( 28370596 )
2017
29
Case series of omalizumab for allergic bronchopulmonary aspergillosis in cystic fibrosis patients. ( 27717223 )
2017
30
F508del CFTR gene mutation in patients with allergic bronchopulmonary aspergillosis. ( 29035608 )
2017
31
Omalizumab treatment for allergic bronchopulmonary aspergillosis in young patients with cystic fibrosis. ( 29173443 )
2017
32
Beneficial effects of Omalizumab therapy in allergic bronchopulmonary aspergillosis: A synthesis review of published literature. ( 27993289 )
2017
33
Allergic bronchopulmonary aspergillosis causing bendopnea. ( 28474666 )
2017
34
Diagnosis of Allergic Bronchopulmonary Aspergillosis Exacerbations. ( 29122158 )
2017
35
Allergic bronchopulmonary aspergillosis treated successfully with omalizumab. ( 28705584 )
2017
36
Allergic Bronchopulmonary Aspergillosis. ( 28483324 )
2017
37
Coexistence of Pulmonary Aspergilloma and Allergic Bronchopulmonary Aspergillosis. ( 28768986 )
2017
38
Allergic Bronchopulmonary Aspergillosis in Cystic Fibrosis: MR Imaging of Airway Mucus Contrasts as a Tool for Diagnosis. ( 28530849 )
2017
39
Allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. ( 28469716 )
2017
40
Increasing Total Serum IgE, Allergic Bronchopulmonary Aspergillosis, and Lung Function in Cystic Fibrosis. ( 28526275 )
2017
41
Successful Treatment of Allergic Bronchopulmonary Aspergillosis With Isavuconazole: Case Report and Review of the Literature. ( 28491888 )
2017
42
Multivariate Analysis As a Support for Diagnostic Flowcharts in Allergic Bronchopulmonary Aspergillosis: A Proof-of-Concept Study. ( 28878778 )
2017
43
Clinical Analysis of 77 Patients with Allergic Bronchopulmonary Aspergillosis in Peking Union Medical College Hospital. ( 28695805 )
2017
44
Question 11: How should Allergic Bronchopulmonary Aspergillosis [ABPA] be managed in Cystic Fibrosis? ( 27964950 )
2016
45
Coexisting atopic conditions influence the likelihood of allergic bronchopulmonary aspergillosis in asthma. ( 27234940 )
2016
46
Molecular-based allergy diagnosis of allergic bronchopulmonary aspergillosis in Aspergillus fumigatus-sensitized Japanese patients. ( 26817858 )
2016
47
Delayed diagnosis of allergic bronchopulmonary aspergillosis due to absence of asthmatic symptoms. ( 27489792 )
2016
48
Allergic bronchopulmonary aspergillosis in asthma. ( 27599560 )
2016
49
Basophil activation test determination of CD63 combined with CD203c is not superior to CD203c alone in identifying allergic bronchopulmonary aspergillosis in cystic fibrosis. ( 27215492 )
2016
50
Combined Allergic Bronchopulmonary Aspergillosis and Eosinophilic Granulomatosis with Polyangiitis: Three Cases and a Review of the Literature. ( 27041167 )
2016

Variations for Allergic Bronchopulmonary Aspergillosis

Expression for Allergic Bronchopulmonary Aspergillosis

Search GEO for disease gene expression data for Allergic Bronchopulmonary Aspergillosis.

Pathways for Allergic Bronchopulmonary Aspergillosis

Pathways related to Allergic Bronchopulmonary Aspergillosis according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.76 CFTR IL4 SFTPD
2 11.68 MBL2 SFTPA2 SFTPD
3
Show member pathways
11.59 CCL17 CFTR IL4 IL5
4 11.23 CCL17 IL4 IL5
5
Show member pathways
11.19 SFTPA2 SFTPD
6
Show member pathways
11.14 SFTPA2 SFTPD
7 11.13 IL4 IL5 SFTPA2
8 11.01 IL4 IL5
9 10.98 IL4 IL5
10 10.93 IL4 IL5
11 10.85 IL4 IL5
12
Show member pathways
10.8 SFTPA2 SFTPD
13 10.46 CCL17 IL4 IL5

GO Terms for Allergic Bronchopulmonary Aspergillosis

Cellular components related to Allergic Bronchopulmonary Aspergillosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 CCL17 EPX IL4 IL5 MBL2 SFTPA2
2 clathrin-coated endocytic vesicle GO:0045334 9.37 SFTPA2 SFTPD
3 collagen trimer GO:0005581 9.33 MBL2 SFTPA2 SFTPD
4 multivesicular body GO:0005771 9.32 SFTPA2 SFTPD
5 lamellar body GO:0042599 9.26 SFTPA2 SFTPD
6 extracellular space GO:0005615 9.17 CCL17 EPX IL4 IL5 MBL2 SFTPA2

Biological processes related to Allergic Bronchopulmonary Aspergillosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 toll-like receptor signaling pathway GO:0002224 9.4 SFTPA2 SFTPD
2 positive regulation of B cell proliferation GO:0030890 9.37 IL4 IL5
3 defense response to bacterium GO:0042742 9.33 EPX MBL2 SFTPD
4 developmental process GO:0032502 9.32 SFTPA2 SFTPD
5 respiratory gaseous exchange GO:0007585 9.26 SFTPA2 SFTPD
6 surfactant homeostasis GO:0043129 8.96 SFTPA2 SFTPD
7 positive regulation of phagocytosis GO:0050766 8.8 MBL2 SFTPA2 SFTPD

Molecular functions related to Allergic Bronchopulmonary Aspergillosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.33 CCL17 IL4 IL5
2 lipopolysaccharide binding GO:0001530 9.26 SFTPA2 SFTPD
3 carbohydrate binding GO:0030246 9.13 MBL2 SFTPA2 SFTPD
4 monosaccharide binding GO:0048029 8.62 SFTPA2 SFTPD

Sources for Allergic Bronchopulmonary Aspergillosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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