MCID: ALL002
MIFTS: 19

Allergic Cutaneous Vasculitis

Categories: Cardiovascular diseases, Immune diseases, Skin diseases

Aliases & Classifications for Allergic Cutaneous Vasculitis

MalaCards integrated aliases for Allergic Cutaneous Vasculitis:

Name: Allergic Cutaneous Vasculitis 12 15
Vasculitis, Leukocytoclastic, Cutaneous 71
Autoimmune Hypersensitivity Angiitis 12
Allergic Cutaneous Angiitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11450
UMLS 71 C0151436

Summaries for Allergic Cutaneous Vasculitis

Disease Ontology : 12 A hypersensitivity vasculitis that results in inflammation of small blood vessels, characterized clinically by palpable purpura, which is a slightly elevated purpuric rash over one or more areas of the skin.

MalaCards based summary : Allergic Cutaneous Vasculitis, also known as vasculitis, leukocytoclastic, cutaneous, is related to vasculitis and allergic hypersensitivity disease. An important gene associated with Allergic Cutaneous Vasculitis is ZBP1 (Z-DNA Binding Protein 1). The drugs leucovorin and Dapsone have been mentioned in the context of this disorder. Affiliated tissues include skin.

Related Diseases for Allergic Cutaneous Vasculitis

Diseases related to Allergic Cutaneous Vasculitis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 vasculitis 10.5
2 allergic hypersensitivity disease 9.9
3 purpura 9.9

Symptoms & Phenotypes for Allergic Cutaneous Vasculitis

Drugs & Therapeutics for Allergic Cutaneous Vasculitis

Drugs for Allergic Cutaneous Vasculitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 42)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
leucovorin Approved Phase 4 58-05-9 6006 143
2
Dapsone Approved, Investigational Phase 4 80-08-0 2955
3
Folic acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
4 Folic Acid Antagonists Phase 4
5 Vitamin B Complex Phase 4
6 Antimalarials Phase 4
7 Folate Phase 4
8 Vitamin B9 Phase 4
9 Anti-Bacterial Agents Phase 4
10 Anti-Infective Agents Phase 4
11 Antiparasitic Agents Phase 4
12 Antiprotozoal Agents Phase 4
13
Methylprednisolone Approved, Vet_approved Phase 2 83-43-2 6741
14
Methylprednisolone hemisuccinate Approved Phase 2 2921-57-5
15 Prednisolone acetate Approved, Vet_approved Phase 2 52-21-1
16
Prednisolone Approved, Vet_approved Phase 2 50-24-8 5755
17
Prednisolone phosphate Approved, Vet_approved Phase 2 302-25-0
18
Prednisolone hemisuccinate Experimental Phase 2 2920-86-7
19 Methylprednisolone Acetate Phase 2
20 Gastrointestinal Agents Phase 2
21 Protective Agents Phase 2
22 Antiemetics Phase 2
23 Anti-Inflammatory Agents Phase 2
24 Neuroprotective Agents Phase 2
25 Hormone Antagonists Phase 2
26 glucocorticoids Phase 2
27 Antineoplastic Agents, Hormonal Phase 2
28 Autonomic Agents Phase 2
29 Hormones Phase 2
30
Cyclophosphamide Approved, Investigational 6055-19-2, 50-18-0 2907
31
Miconazole Approved, Investigational, Vet_approved 22916-47-8 4189
32
Prednisone Approved, Vet_approved 53-03-2 5865
33
Lenograstim Approved, Investigational 135968-09-1
34 Alkylating Agents
35 Immunologic Factors
36 Dermatologic Agents
37 Antilymphocyte Serum
38 Immunosuppressive Agents
39 Antirheumatic Agents
40 Antifungal Agents
41 Calcineurin Inhibitors
42 Cyclosporins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase IV, Randomised, Multicentre, Double-blind, Study to Evaluate the Clinical Utility of Prospective Genetic Screening (HLA-B*1301) for Susceptibility to Dapsone Hypersensitivity Syndrome Unknown status NCT02550080 Phase 4 Dapsone
2 Phase II Study of Prednisolone/Methylprednisolone Absorption in Children With Juvenile Dermatomyositis Completed NCT00004357 Phase 2 Methylprednisolone;Prednisolone
3 Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases Unknown status NCT00006055 anti-thymocyte globulin;cyclophosphamide;cyclosporine;filgrastim;methylprednisolone;prednisone

Search NIH Clinical Center for Allergic Cutaneous Vasculitis

Genetic Tests for Allergic Cutaneous Vasculitis

Anatomical Context for Allergic Cutaneous Vasculitis

MalaCards organs/tissues related to Allergic Cutaneous Vasculitis:

40
Skin

Publications for Allergic Cutaneous Vasculitis

Articles related to Allergic Cutaneous Vasculitis:

(show all 14)
# Title Authors PMID Year
1
Possible pathogenetic mechanisms in allergic cutaneous vasculitis. 61
3292447 1988
2
Delayed hypersensitivity and differences of histologic pattern in allergic cutaneous vasculitis. 61
3364802 1988
3
[Ulcerative lesions of the legs as a manifestation of allergic cutaneous vasculitis]. 61
3381389 1988
4
[Experience using hemosorption therapy in allergic cutaneous vasculitis]. 61
6117996 1981
5
[Histamine content of blood and the use of antihistaminic drugs in allergic cutaneous vasculitis]. 61
33509 1978
6
[Allergic cutaneous vasculitis]. 61
724469 1978
7
[Symptomatic or secondary allergic vasculitis. Pathogenesis of cutaneous vasculitis]. 61
1240560 1975
8
[Allergic cutaneous vasculitis (purpura Schönlein-Henoch) (author's transl)]. 61
804593 1975
9
[Pathogenetic considerations on an unusual case of allergic cutaneous vasculitis]. 61
5558154 1971
10
Erythema nodosum: a form of allergic cutaneous vasculitis. 61
5664515 1968
11
Allergic cutaneous vasculitis report of a case. 61
13835070 1959
12
Allergic cutaneous vasculitis; report of a unique case. 61
13371912 1956
13
A case of allergic cutaneous vasculitis (arteriolitis allergica). 61
13032316 1953
14
Allergic cutaneous vasculitis. 61
14932676 1952

Variations for Allergic Cutaneous Vasculitis

Expression for Allergic Cutaneous Vasculitis

Search GEO for disease gene expression data for Allergic Cutaneous Vasculitis.

Pathways for Allergic Cutaneous Vasculitis

GO Terms for Allergic Cutaneous Vasculitis

Sources for Allergic Cutaneous Vasculitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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