Allergic Hypersensitivity Disease

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Disease Ontology 12 DOID:1205 ICD10 33 T78.40 T78.4 MeSH 44 D006967

NCIt 50 C3114 SNOMED-CT 68 106190000 127072000 157754004 157758001 212998004 212999007 21957007 257550005 269284003 269432007 274211000 282092005 418168000 418634005 418925002 421668005 421961002 91232002 more UMLS 73 C0020517 C0851444 C1527304 C3539909 more

MedlinePlus : ⁴³ An allergy is a reaction by your immune system to something that does not bother most other people. People who have allergies often are sensitive to more than one thing. Substances that often cause reactions are Pollen Dust mites Mold spores Pet dander Food Insect stings Medicines Normally, your immune system fights germs. It is your body's defense system. In most allergic reactions, however, it is responding to a false alarm. Genes and the environment probably both play a role. Allergies can cause a variety of symptoms such as a runny nose, sneezing, itching, rashes, swelling, or asthma. Allergies can range from minor to severe. Anaphylaxis is a severe reaction that can be life-threatening. Doctors use skin and blood tests to diagnose allergies. Treatments include medicines, allergy shots, and avoiding the substances that cause the reactions. NIH: National Institute of Allergy and Infectious Diseases

MalaCards based summary : Allergic Hypersensitivity Disease, also known as hypersensitivity, is related to extrinsic allergic alveolitis and hypersensitivity reaction type iv disease, and has symptoms including coughing, exanthema and pruritus. An important gene associated with Allergic Hypersensitivity Disease is IL5 (Interleukin 5), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. Affiliated tissues include skin, testes and tongue, and related phenotypes are hematopoietic system and immune system

Disease Ontology : ¹² An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.

PubMed Health : ⁶³ About allergies: Allergies arise if the body's immune system overreacts to foreign substances (allergens) that are usually harmless in most people, such as pollen or certain foods. The symptoms can vary a lot. In some cases they are quite mild, but they can also be a real nuisance and have a considerable impact in everyday life. Severe allergic reactions may be life-threatening.There are various treatment options for allergies. Some things that trigger allergies (allergens) are easy to avoid, whereas others aren't. Common allergens include the following:

Wikipedia : ⁷⁶ Hypersensitivity (also called hypersensitivity reaction or intolerance) refers to undesirable reactions... more...

The best way to prevent allergic reactions is to avoid contact with the triggers (allergens). How well this works will mainly depend on the type of trigger. It’s often quite easy to avoid contact with things like certain foods or chemical substances. It’s almost impossible to avoid pollen, though. But pollen calendars and forecasts, for instance on the internet, can give you an idea of the pollen count in certain regions. People with dust mite allergies can somewhat lower their exposure to dust mites in their home by taking precautions such as using mite-proof bedding and removing "dust traps."The symptoms of many allergies can be treated with medication. Antihistamines and steroids are often used for this purpose. These medications are available in various forms, including tablets, nasal sprays and injections. They are mainly used in the treatment of allergic rhinitis (in the nose) and allergic conjunctivitis (in the eyes). Allergic reactions affecting the skin are also treated using steroid ointments or creams.A treatment known as allergen-specific immunotherapy (“desensitization”) can help reduce sensitivity to some allergens in the long term. Like with vaccines, this treatment approach involves exposing people to small amounts of the allergen. Here it is done at regular intervals by either injecting the allergen into your skin or placing it under your tongue. It takes about three to five years to complete allergen-specific immunotherapy. This approach is mainly used for the treatment of allergies to pollen (hay fever), dust mites and insect venom.There is currently no evidence that herbal or homeopathic products can help in the treatment of allergies. This is also true for acupuncture.

Search Clinical Trials , NIH Clinical Center for Allergic Hypersensitivity Disease

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Search GEO for disease gene expression data for Allergic Hypersensitivity Disease.