MCID: ALL007
MIFTS: 29

Allergic Urticaria

Categories: Immune diseases, Skin diseases

Aliases & Classifications for Allergic Urticaria

MalaCards integrated aliases for Allergic Urticaria:

Name: Allergic Urticaria 12 15 17 74

Classifications:



External Ids:

Disease Ontology 12 DOID:10612
ICD9CM 36 708.0
SNOMED-CT 69 40178009
ICD10 34 L50.0
UMLS 74 C0149526

Summaries for Allergic Urticaria

Disease Ontology : 12 An urticaria that is characterized by erythematous papules and plaques, has symptom pruritis, and has material basis in allergic reaction.

MalaCards based summary : Allergic Urticaria is related to urticaria and angioedema, and has symptoms including pruritis An important gene associated with Allergic Urticaria is FCER1A (Fc Fragment Of IgE Receptor Ia), and among its related pathways/superpathways is Complement and coagulation cascades. The drugs Acidophilus and Caseins have been mentioned in the context of this disorder. Affiliated tissues include skin, pituitary and cortex.

Wikipedia : 77 Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps. They may also burn... more...

Related Diseases for Allergic Urticaria

Graphical network of the top 20 diseases related to Allergic Urticaria:



Diseases related to Allergic Urticaria

Symptoms & Phenotypes for Allergic Urticaria

Symptoms:

12
  • pruritis

Drugs & Therapeutics for Allergic Urticaria

Drugs for Allergic Urticaria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Acidophilus Phase 2,Not Applicable
2 Caseins Not Applicable
3 Chelating Agents Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Primary Prevention of Allergic Disease in Early Child by Lactobacillus Reuteri Completed NCT01285830 Phase 2
2 Effect Of Lactobacillus GG on Atopic March Unknown status NCT01891916 Not Applicable

Search NIH Clinical Center for Allergic Urticaria

Genetic Tests for Allergic Urticaria

Anatomical Context for Allergic Urticaria

MalaCards organs/tissues related to Allergic Urticaria:

42
Skin, Pituitary, Cortex, Adrenal Cortex, Adrenal Gland

Publications for Allergic Urticaria

Articles related to Allergic Urticaria:

(show all 11)
# Title Authors Year
1
A Case of Allergic Urticaria After Ophthalmic Nepafenac Use. ( 29988879 )
2018
2
Atopic Dermatitis and Allergic Urticaria: Cutaneous Manifestations of Immunodeficiency. ( 27886899 )
2017
3
Allergic urticaria: a case report of rare skin allergy with a common mouthwash. ( 23372227 )
2013
4
Allergic urticaria from tonic water. ( 11991290 )
2002
5
A case of allergic urticaria caused by erythritol. ( 10774141 )
2000
6
Allergic urticaria and angioedema caused by a hemostatic sponge of bovine fibrin used in tooth extraction. ( 8721528 )
1996
7
Cimetidine treatment of recalcitrant acute allergic urticaria. ( 3777596 )
1986
8
Allergic urticaria and hereditary angioedema. Independent association in the same patient. ( 6509770 )
1984
9
Ceruloplasmin acitivity in chronic allergic urticaria. ( 5575638 )
1971
10
Conditioned reflex allergic urticaria. ( 14484547 )
1961
11
Electrocardiographic changes associated with allergic urticaria. ( 14493320 )
1961

Variations for Allergic Urticaria

Expression for Allergic Urticaria

Search GEO for disease gene expression data for Allergic Urticaria.

Pathways for Allergic Urticaria

Pathways related to Allergic Urticaria according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.94 KNG1 SERPINA1 SERPING1

GO Terms for Allergic Urticaria

Cellular components related to Allergic Urticaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 collagen-containing extracellular matrix GO:0062023 9.13 KNG1 SERPINA1 SERPING1
2 platelet alpha granule lumen GO:0031093 8.8 KNG1 SERPINA1 SERPING1

Biological processes related to Allergic Urticaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.54 KNG1 SERPINA1 SERPING1
2 negative regulation of endopeptidase activity GO:0010951 9.43 KNG1 SERPINA1 SERPING1
3 cellular response to dexamethasone stimulus GO:0071549 9.4 CRH NR3C1
4 platelet degranulation GO:0002576 9.33 KNG1 SERPINA1 SERPING1
5 blood coagulation, intrinsic pathway GO:0007597 9.32 KNG1 SERPING1
6 negative regulation of peptidase activity GO:0010466 9.13 KNG1 SERPINA1 SERPING1
7 hemostasis GO:0007599 8.8 KNG1 SERPINA1 SERPING1

Molecular functions related to Allergic Urticaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase inhibitor activity GO:0004867 8.96 SERPINA1 SERPING1
2 peptidase inhibitor activity GO:0030414 8.8 KNG1 SERPINA1 SERPING1

Sources for Allergic Urticaria

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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