MCID: ALL007
MIFTS: 28

Allergic Urticaria

Categories: Immune diseases, Skin diseases

Aliases & Classifications for Allergic Urticaria

MalaCards integrated aliases for Allergic Urticaria:

Name: Allergic Urticaria 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10612
ICD10 33 L50.0
ICD9CM 35 708.0
SNOMED-CT 68 40178009
UMLS 73 C0149526

Summaries for Allergic Urticaria

MalaCards based summary : Allergic Urticaria is related to urticaria and angioedema. An important gene associated with Allergic Urticaria is SERPING1 (Serpin Family G Member 1), and among its related pathways/superpathways is Complement and coagulation cascades. The drugs Acidophilus and Caseins have been mentioned in the context of this disorder. Affiliated tissues include skin, cortex and pituitary.

Wikipedia : 76 Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps. They may also burn... more...

Related Diseases for Allergic Urticaria

Graphical network of the top 20 diseases related to Allergic Urticaria:



Diseases related to Allergic Urticaria

Symptoms & Phenotypes for Allergic Urticaria

Drugs & Therapeutics for Allergic Urticaria

Drugs for Allergic Urticaria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Acidophilus Phase 2,Not Applicable
2 Caseins Not Applicable
3 Chelating Agents Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Primary Prevention of Allergic Disease in Early Child by Lactobacillus Reuteri Completed NCT01285830 Phase 2
2 Effect Of Lactobacillus GG on Atopic March Unknown status NCT01891916 Not Applicable

Search NIH Clinical Center for Allergic Urticaria

Genetic Tests for Allergic Urticaria

Anatomical Context for Allergic Urticaria

MalaCards organs/tissues related to Allergic Urticaria:

41
Skin, Cortex, Pituitary, Adrenal Gland, Adrenal Cortex

Publications for Allergic Urticaria

Articles related to Allergic Urticaria:

(show all 11)
# Title Authors Year
1
A Case of Allergic Urticaria After Ophthalmic Nepafenac Use. ( 29988879 )
2018
2
Atopic Dermatitis and Allergic Urticaria: Cutaneous Manifestations of Immunodeficiency. ( 27886899 )
2017
3
Allergic urticaria: a case report of rare skin allergy with a common mouthwash. ( 23372227 )
2013
4
Allergic urticaria from tonic water. ( 11991290 )
2002
5
A case of allergic urticaria caused by erythritol. ( 10774141 )
2000
6
Allergic urticaria and angioedema caused by a hemostatic sponge of bovine fibrin used in tooth extraction. ( 8721528 )
1996
7
Cimetidine treatment of recalcitrant acute allergic urticaria. ( 3777596 )
1986
8
Allergic urticaria and hereditary angioedema. Independent association in the same patient. ( 6509770 )
1984
9
Ceruloplasmin acitivity in chronic allergic urticaria. ( 5575638 )
1971
10
Electrocardiographic changes associated with allergic urticaria. ( 14493320 )
1961
11
Conditioned reflex allergic urticaria. ( 14484547 )
1961

Variations for Allergic Urticaria

Expression for Allergic Urticaria

Search GEO for disease gene expression data for Allergic Urticaria.

Pathways for Allergic Urticaria

Pathways related to Allergic Urticaria according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.94 KNG1 SERPINA1 SERPING1

GO Terms for Allergic Urticaria

Cellular components related to Allergic Urticaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 CRH ENSG00000264813 KNG1 SERPINA1 SERPING1
2 collagen-containing extracellular matrix GO:0062023 9.13 KNG1 SERPINA1 SERPING1
3 platelet alpha granule lumen GO:0031093 8.8 KNG1 SERPINA1 SERPING1

Biological processes related to Allergic Urticaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.54 KNG1 SERPINA1 SERPING1
2 negative regulation of endopeptidase activity GO:0010951 9.43 KNG1 SERPINA1 SERPING1
3 cellular response to dexamethasone stimulus GO:0071549 9.4 CRH NR3C1
4 platelet degranulation GO:0002576 9.33 KNG1 SERPINA1 SERPING1
5 blood coagulation, intrinsic pathway GO:0007597 9.32 KNG1 SERPING1
6 negative regulation of peptidase activity GO:0010466 9.13 KNG1 SERPINA1 SERPING1
7 hemostasis GO:0007599 8.8 KNG1 SERPINA1 SERPING1

Molecular functions related to Allergic Urticaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase inhibitor activity GO:0004867 8.96 SERPINA1 SERPING1
2 peptidase inhibitor activity GO:0030414 8.8 KNG1 SERPINA1 SERPING1

Sources for Allergic Urticaria

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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