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MCID: ALV002
MIFTS: 54

Alveolar Echinococcosis

Categories: Gastrointestinal diseases, Infectious diseases, Liver diseases, Neuronal diseases, Rare diseases, Respiratory diseases
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Aliases & Classifications for Alveolar Echinococcosis

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MalaCards integrated aliases for Alveolar Echinococcosis:

Name: Alveolar Echinococcosis 11 19 58 75 43 14 71
Echinococcus Multilocularis Infection 11 58 71
Echinococcosis 19 71
Multilocular Hydatid 11
Small Fox Tapeworm 11
Alveolococcosis 11

Characteristics:


Prevelance:

1-9/1000000 (Europe, Switzerland) <1/1000000 (Poland, France) 1-9/100000 (Austria) 58

Age Of Onset:

Adult,Elderly 58

Classifications:

MalaCards categories:
Global: Rare diseases Infectious diseases
Anatomical: Gastrointestinal diseases Respiratory diseases Neuronal diseases Liver diseases
See all MalaCards categories (disease lists)
ICD10: 31 32
Orphanet: 58  
Rare infectious diseases


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Summaries for Alveolar Echinococcosis

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GARD: 19 A rare parasitic disorder that occurs after ingestion of eggs of Echinococcus multilocularis and characterized by an initial asymptomatic incubation period of many years followed by a chronic course where the clinical manifestations include epigastric pain and jaundice.

MalaCards based summary: Alveolar Echinococcosis, also known as echinococcus multilocularis infection, is related to echinococcosis and cystic echinococcosis. An important gene associated with Alveolar Echinococcosis is CES2 (Carboxylesterase 2), and among its related pathways/superpathways are T-cell activation SARS-CoV-2 and IL12-mediated signaling events. The drugs Metronidazole and Albendazole have been mentioned in the context of this disorder. Affiliated tissues include liver, spleen and brain, and related phenotypes are eosinophilia and elevated erythrocyte sedimentation rate

Orphanet: 58 A rare parasitic disorder that occurs after ingestion of eggs of Echinococcus multilocularis and characterized by an initial asymptomatic incubation period of many years followed by a chronic course where the clinical manifestations include epigastric pain and jaundice.

Disease Ontology: 11 An echinococcosis that is caused by the larvae of Echinococcus multilocularis affecting the liver as a slow growing, destructive tumor, with abdominal pain, biliary obstruction, and occasionally metastatic lesions into the lungs and brain.

Wikipedia: 75 Alveolar hydatid disease (AHD) is a form of echinococcosis, or a disease that originates from a... more...
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Related Diseases for Alveolar Echinococcosis

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Diseases related to Alveolar Echinococcosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 676)
# Related Disease Score Top Affiliating Genes
1 echinococcosis 32.4 MT-CO1 IL5 IL10 CD8A
2 cystic echinococcosis 30.9 RRAGB MT-ND1 MT-CO1 IL4 IL10 CES2
3 schistosomiasis 30.6 IL5 IL4 IL10
4 toxoplasmosis 30.6 IL5 IL4 IL10
5 coenurosis 30.5 MT-ND1 MT-CO1
6 trichinosis 30.4 IL5 IL4 IL10 CD4
7 sparganosis 30.4 MT-ND1 MT-CO1
8 polycystic echinococcosis 30.3 MT-ND1 MT-CO1 CES1
9 actinomycosis 30.3 IL10 CD4
10 fascioliasis 30.3 MT-ND1 MT-CO1 IL4 IL10
11 aspergillosis 30.3 IL5 IL4 IL10
12 colitis 30.2 IL5 IL4 IL10 CD4
13 leishmaniasis 30.2 IL5 IL4 IL10
14 cysticercosis 30.2 MT-ND1 MT-CO1 IL5 IL4 IL10 CES2
15 amebiasis 30.1 IL4 IL10 CD4
16 glanders 30.1 CD8A CD4
17 toxocariasis 30.1 IL5 IL4 IL10
18 autoimmune lymphoproliferative syndrome 30.1 MT-CO1 IL10 CD8A CD4
19 granulomatous hepatitis 30.0 CD8A CD4
20 urinary schistosomiasis 29.9 IL5 IL4 IL10 CD4
21 urticaria 29.9 IL5 IL4 IL10 CD4
22 sclerosing cholangitis 29.9 IL10 CD8A CD4
23 giardiasis 29.8 IL10 CD8A CD4
24 bronchopneumonia 29.8 IL10 CD8A CD4
25 allergic disease 29.8 IL5 IL4 IL10 CD8A CD4
26 ascaris lumbricoides infection 29.8 MT-ND1 IL5 IL4 IL10 CD4
27 enterobiasis 29.8 MT-CO1 IL5 IL4
28 strongyloidiasis 29.8 MT-CO1 IL5 IL4 IL10 CD4
29 intestinal schistosomiasis 29.8 MT-CO1 IL5 IL4 IL10 CD4
30 severe combined immunodeficiency 29.7 IL5 IL4 IL10 CD8A CD4
31 drug allergy 29.7 IL5 IL4 CD4
32 lymphangioma 29.7 IL10 CD8A CD4
33 bronchiolitis 29.7 IL5 IL4 IL10
34 hyper ige syndrome 29.7 IL4 IL10 CD8A CD4
35 gastroduodenitis 29.7 CD8A CD4
36 cholangitis, primary sclerosing 29.7 IL4 IL10 CD8A CD4
37 bone inflammation disease 29.7 IL4 IL10 CD8A CD4
38 filariasis 29.6 MT-CO1 IL5 IL4 IL10 CD4
39 listeriosis 29.6 IL4 IL10 CD8A CD4
40 bronchitis 29.6 IL5 IL4 IL10
41 viral encephalitis 29.6 IL10 CD8A CD4
42 poliomyelitis 29.6 IL10 CD8A CD4
43 thrombocytopenia due to platelet alloimmunization 29.6 IL10 CD8A CD4
44 panuveitis 29.6 IL10 CD8A CD4
45 dengue disease 29.6 IL10 CD8A CD4
46 aplastic anemia 29.5 IL4 IL10 CD8A CD4
47 parasitic helminthiasis infectious disease 29.5 MT-ND1 MT-CO1 IL5 IL4 IL10 CES2
48 chronic asthma 29.5 IL5 IL4 IL10 CD8A CD4
49 miliary tuberculosis 29.4 IL4 IL10 CD8A CD4
50 t cell deficiency 29.4 IL4 IL10 CD8A CD4

Graphical network of the top 20 diseases related to Alveolar Echinococcosis:



Diseases related to Alveolar Echinococcosis
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Symptoms & Phenotypes for Alveolar Echinococcosis

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Human phenotypes related to Alveolar Echinococcosis:

58 30 (show top 50) (show all 52)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 eosinophilia 58 30 Hallmark (90%) Very frequent (99-80%)
 HP:0001880
2 elevated erythrocyte sedimentation rate 58 30 Hallmark (90%) Very frequent (99-80%)
 HP:0003565
3 hepatic cysts 58 30 Hallmark (90%) Very frequent (99-80%)
 HP:0001407
4 increased circulating antibody level 30 Hallmark (90%) HP:0010702
5 fatigue 58 30 Frequent (33%) Frequent (79-30%)
 HP:0012378
6 fever 58 30 Frequent (33%) Frequent (79-30%)
 HP:0001945
7 anemia 58 30 Frequent (33%) Frequent (79-30%)
 HP:0001903
8 jaundice 58 30 Frequent (33%) Frequent (79-30%)
 HP:0000952
9 abdominal pain 58 30 Frequent (33%) Frequent (79-30%)
 HP:0002027
10 pedal edema 58 30 Frequent (33%) Frequent (79-30%)
 HP:0010741
11 decreased liver function 58 30 Frequent (33%) Frequent (79-30%)
 HP:0001410
12 asthenia 58 30 Frequent (33%) Frequent (79-30%)
 HP:0025406
13 epigastric pain 58 30 Frequent (33%) Frequent (79-30%)
 HP:0410019
14 low back pain 58 30 Frequent (33%) Frequent (79-30%)
 HP:0003419
15 hemoptysis 58 30 Occasional (7.5%) Occasional (29-5%)
 HP:0002105
16 dyspnea 58 30 Occasional (7.5%) Occasional (29-5%)
 HP:0002094
17 cough 58 30 Occasional (7.5%) Occasional (29-5%)
 HP:0012735
18 chest pain 58 30 Occasional (7.5%) Occasional (29-5%)
 HP:0100749
19 weight loss 58 30 Occasional (7.5%) Occasional (29-5%)
 HP:0001824
20 headache 58 30 Occasional (7.5%) Occasional (29-5%)
 HP:0002315
21 renal cyst 58 30 Occasional (7.5%) Occasional (29-5%)
 HP:0000107
22 ectopic calcification 58 30 Occasional (7.5%) Occasional (29-5%)
 HP:0010766
23 abnormal spleen morphology 58 30 Occasional (7.5%) Occasional (29-5%)
 HP:0025408
24 abnormality of adrenal morphology 58 30 Occasional (7.5%) Occasional (29-5%)
 HP:0011732
25 cholangitis 58 30 Occasional (7.5%) Occasional (29-5%)
 HP:0030151
26 cutaneous abscess 58 30 Occasional (7.5%) Occasional (29-5%)
 HP:0031292
27 pulmonary cyst 58 30 Occasional (7.5%) Occasional (29-5%)
 HP:0032445
28 abnormal sternum morphology 30 Occasional (7.5%) HP:0000766
29 seizure 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0001250
30 ataxia 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0001251
31 dysarthria 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0001260
32 increased intracranial pressure 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0002516
33 abnormal vertebral morphology 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0003468
34 vomiting 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0002013
35 portal hypertension 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0001409
36 biliary cirrhosis 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0002613
37 vertigo 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0002321
38 liver abscess 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0100523
39 bone cyst 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0012062
40 pancreatic cysts 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0001737
41 aphasia 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0002381
42 hemiparesis 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0001269
43 abnormal pericardium morphology 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0001697
44 abnormality of mesentery morphology 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0100016
45 budd-chiari syndrome 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0002639
46 intracranial cystic lesion 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0010576
47 abnormal pelvis bone morphology 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0040163
48 abnormality of the diaphragm 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0000775
49 abnormality of bladder morphology 58 30 Very rare (1%) Very rare (<4-1%)
 HP:0025487
50 abnormality of the sternum 58 Occasional (29-5%)

MGI Mouse Phenotypes related to Alveolar Echinococcosis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.28 CD4 CD8A CES1 CES2 EML1 EPPIN
Sources

Drugs & Therapeutics for Alveolar Echinococcosis

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Drugs for Alveolar Echinococcosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metronidazole Approved 443-48-1, 69198-10-3 4173
2
Albendazole Approved, Vet_approved 54965-21-8 2082
3
Mebendazole Approved, Vet_approved 31431-39-7 4030
4
Benzimidazole Experimental, Investigational 51-17-2 5798
5 Antiparasitic Agents
6 Liver Extracts
7 Anti-Infective Agents
8 Antimitotic Agents
9 Antiprotozoal Agents
10 Anthelmintics
11 Tubulin Modulators
12 Pharmaceutical Solutions
13 Anesthetics

Interventional clinical trials:

(show all 18)
# Name Status NCT ID Phase Drugs
1 Liver Echinococcosis; Jaundice as Initial Presentation, Short and Long Term Results of Surgical Treatment Unknown status NCT04271176
2 Multi-metric Quantitative MRI for the Assessment of Hepatic Hydatid Disease- a Pilot Study Unknown status NCT03289884
3 Analysis of the Potentially Parasitocidal Effect of a Long Term Chemotherapy With Benzimidazoles in Patients With Inoperable Alveolar Echinococcosis Using PET-CT and EmII/3-10 Serology Completed NCT00658294
4 Comprehensive Diagnosis and Treatment of Alveolar Echinococcosis : A Single-center, Longterm Observational Study of 312 Patients in Germany Completed NCT02509884
5 Alveolar Echinococcosis: Parasite Viability and Innovative Markers for Follow-up of Patients Treated With Albendazole - EchinoVISTA Prospective Clinical Study Completed NCT02876146 Benzimidazole
6 Laparoscopic Versus Open Conservative Surgery for the Management of Cystic Echinococcosis of the Liver: Prospective, Randomized, and Controlled Clinical Trial of Efficacy and Safety Completed NCT01643018
7 VATS Versus Thoracotomy for Pulmonary Hydatid Disease Completed NCT04412512
8 Surgical Treatment of Hepatic Hydatidosis in Elderly Patients Completed NCT05113550
9 The Influence of Two Different Hepatectomy Methods on Transection Speed and Chemokine Release From the Liver Completed NCT01785212
10 Outcome After Surgical Treatment of Liver Hydatid Cyst Completed NCT05420155
11 Periprosthetic Pathologic Fracture Following Tibial Echinococcosis: A Case Report Completed NCT03622346
12 Management of Liver Hydatid Cysts: A Retrospective Analysis of 293 Cases From Southern Iran Completed NCT04363151
13 Epidemiology of Human Cystic Hydatid Disease Completed NCT00138346
14 Splenic Preserving Surgery in Hydatid Spleen Completed NCT04890899
15 Intracranial Hydatid Cyst: Series of 8 Cases Completed NCT04454268
16 Occult Cysto-biliary Communication and Cyst Fluid Analysis Predicts Post-operative Biliary Fistula and Late Recurrence After Laparoscopic Partial Cystectomy With Omentoplasty in Solitary Primary Adult Liver Hydatid Cyst Disease - A Prospective Multicenter Study. Completed NCT05116735
17 Radical Versus Conservative Surgical Treatment of Liver Hydatid Cysts: A Propensity Score Matching Analysis Completed NCT04988958
18 Systematic Review of Hypernatremia Following Hydatid Cyst Treatment Recruiting NCT05090020

Search NIH Clinical Center for Alveolar Echinococcosis

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Albendazole

Cochrane evidence based reviews: alveolar echinococcosis

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Genetic Tests for Alveolar Echinococcosis

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Anatomical Context for Alveolar Echinococcosis

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Organs/tissues related to Alveolar Echinococcosis:

MalaCards : Liver, Spleen, Brain, Bone, Skeletal Muscle, Lung, Heart
Sources

Publications for Alveolar Echinococcosis

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Articles related to Alveolar Echinococcosis:

(show top 50) (show all 8170)
# Title Authors PMID Year
1
Mediastinal and pericardial hydatidosis: A case report with review of the literature. 62
36465165 2023
2
The impact of natural environment on human alveolar echinococcosis: A township-level modeling study in Qinghai-Tibet Plateau. 62
36179829 2023
3
[Extended Liver Resection with Complex Vascular Reconstruction in Locally Advanced Alveolar Echinococcosis]. 62
35500589 2022
4
7T Small Animal MRI Research for Hepatic Alveolar Echinococcosis. 62
36469640 2022
5
Risk factors for post-endoscopic retrograde cholangiopancreatography cholangitis in patients with hepatic alveolar echinococcosis-an observational study. 62
35792762 2022
6
Application of hepatic lobe hyperplasia techniques in the treatment of advanced hepatic alveolar echinococcosis: a single-centre experience. 62
36474286 2022
7
Data on the combined effect of atovaquone, mefloquine, and 3-bromopyruvic acid against Echinococcus multilocularis protoscoleces. 62
36426011 2022
8
Primary pancreatic echinococcosis: A rare mimicking of choledochal cyst. 62
35792036 2022
9
Tropical parasitic itch in returned travellers and immigrants from endemic areas. 62
35793476 2022
10
A CT-based radiomics nomogram for the differentiation of pulmonary cystic echinococcosis from pulmonary abscess. 62
36181541 2022
11
Efficacy of Mesenchymal Stem Cells Therapy in Parasitic Infections: Are Anti-parasitic Drugs Combined with MSCs More Effective? 62
36280646 2022
12
First detection of Echinococcus multilocularis in Bosnia and Herzegovina. 62
36406035 2022
13
Authors' Response to Letter "Inaccurate sonographic diagnosis of hepatic CE can be dangerous - Remarks on "Echinococcosis: a Challenge for Liver Sonography" by W. Kratzer et al Ultraschall in Med. 24 February 2022." 62
36323328 2022
14
Mathematical modelling of echinococcosis in human, dogs and sheep with intervention. 62
35635312 2022
15
Severe multilobar lung echinococcosis with multiorgan involvement in a child. 62
35962551 2022
16
Anti-echinococcal effects of sumac, Rhus coriaria, in a murine model of cystic echinococcosis: Parasitological and molecular evaluation. 62
36244447 2022
17
A Comparative Evaluation of Four Different Immunoassays in the Diagnosis of Cystic Echinococcosis Using a Crude and Purified Hydatid Cyst Fluid Antigen. 62
36125652 2022
18
Meta-analysis of the prevalence of bovine cystic echinococcosis in China during decade. 62
36150257 2022
19
Deciphering the role of miR-71 and let-7 in the fertility of cystic echinococcosis cysts: a preliminary assessment. 62
36266590 2022
20
'Fight the parasite': raising awareness of cystic echinococcosis in primary school children in endemic countries. 62
36461072 2022
21
Isolated peritoneal involvement as a primary manifestation of cystic echinococcosis. 62
36435190 2022
22
Inaccurate Sonographic Diagnosis of Hepatic CE Can Be Dangerous - Remarks on "Echinococcosis: A Challenge for Liver Sonography" by W. Kratzer et al Ultraschall in Med. 24 February 2022. 62
35944579 2022
23
In vitro efficacy of albendazole-loaded β-cyclodextrin against protoscoleces of Echinococcus granulosus sensu stricto. 62
36384195 2022
24
Alterations in Gut Microbiota Profiles of Mice Infected with Echinococcus granulosus sensu lato Microbiota Profiles of Mice Infected with E. granulosus s.l. 62
36048399 2022
25
A rare case of hydatid cyst of the neck with concurrent pulmonary hydatid disease. 62
36457772 2022
26
Genotyping and Identification of Antigen B Gene Polymorphism of Echinococcus granulosus in Edirne, Thrace, and the First Report of Genotype G2 (Tasmanian Sheep Strain) in Turkey 62
36194122 2022
27
Brief report prevalence of Echinococcus species in wild foxes in parts of Qinghai Province, China. 62
36333528 2022
28
In Silico Evaluation of the Haplotype Diversity, Phylogenetic Variation and Population Structure of Human E. granulosus sensu stricto (G1 Genotype) Sequences. 62
36422598 2022
29
Isolated primary hydatid cyst of the pancreas: Management challenges of a cystic masquerade. 62
35995585 2022
30
Experimental treatment of cystic echinococcosis: Combination therapy with carvacrol and thymol versus albendazole. 62
36435216 2022
31
The hepato-cardiac disorders in Tibetan residents with hepatic echinococcosis: A case-control echocardiography study. 62
36353905 2022
32
Comparative analysis of anti-relapse treatment regimens in 110 patients with hepatic and pulmonary hydatid echinococcosis. 62
36459040 2022
33
Comment on "Usefulness of the FDG PET/CT in the management of cystic echinococcosis: A pilot study". 62
36462531 2022
34
[Feasibility of ultrasound radiomics-based models for classification of hepatic echinococcosis]. 62
36464267 2022
35
The occurrence of cystic echinococcosis in slaughtered livestock in Jahrom, south of Iran. 62
36118047 2022
36
Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE project. 62
36427513 2022
37
Surgical Management of Cardiac Cystic Echinococcosis in a Pediatric Patient: A Case Report. 62
36420984 2022
38
Serum Level of egr-miR-2a-3p as a Potential Diagnostic Biomarker for Cystic Echinococcosis. 62
36434379 2022
39
Single-Cell Heterogeneity of the Liver-Infiltrating Lymphocytes in Individuals with Chronic Echinococcus multilocularis Infection. 62
36317875 2022
40
Research progress in the proteomics of Echinococcus multilocularis and alveolar echinococcosis. 62
36334997 2022
41
[Research progress on infiltrating zone and microvascular invasion of hepatic alveolar echinococcosis]. 62
36274623 2022
42
Multidetector computed tomography assessment of venous invasion in hepatic alveolar echinococcosis. 62
36207628 2022
43
Evaluating the Benefits and Risks of Ex Vivo Liver Resection and Autotransplantation in Treating Hepatic End-stage Alveolar Echinococcosis. 62
35271705 2022
44
Robotic Liver Surgery for Alveolar Echinococcosis: A Single-Centre Experience. 62
36365027 2022
45
Evaluation of the Metabolic Activity of the Infiltration and Proliferation Areas of Hepatic Alveolar Echinococcosis in Rats Using Contrast-Enhanced Ultrasound. 62
36315997 2022
46
Targeting Echinococcus multilocularis PIM kinase for improving anti-parasitic chemotherapy. 62
36190997 2022
47
Immunization with EmCRT-Induced Protective Immunity against Echinococcus multilocularis Infection in BALB/c Mice. 62
36288020 2022
48
Monocyte-derived macrophages: The supplements of hepatic macrophage in Echinococcus multilocularis infected mice. 62
36169259 2022
49
Societal drivers of human echinococcosis in China. 62
36271415 2022
50
The dual burden of animal and human zoonoses: A systematic review. 62
36240240 2022
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Variations for Alveolar Echinococcosis

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Expression for Alveolar Echinococcosis

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Search GEO for disease gene expression data for Alveolar Echinococcosis.
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Pathways for Alveolar Echinococcosis

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Pathways related to Alveolar Echinococcosis according to GeneCards Suite gene sharing:

(show all 18)
# Super pathways Score Top Affiliating Genes
1
T-cell activation SARS-CoV-2 74
Show member pathways
 11.9 IL5 IL4 IL10 CD8A CD4
2
IL12-mediated signaling events 61
Show member pathways
 11.8 IL4 CD8A CD4
3
Allograft rejection 74
11.7 IL5 IL4 IL10
4
TP53 Regulates Metabolic Genes 66
11.65 RRAGB MT-CO1 GPI
5
Hematopoietic Stem Cells and Lineage-specific Markers 65
11.62 IL5 IL4 IL10 CD8A CD4
6
Dendritic Cells Developmental Lineage Pathway 65
11.56 IL10 CD8A CD4
7
AP-1 transcription factor network 61
11.51 IL5 IL4 IL10
8
IL4-mediated signaling events 61
11.43 IL5 IL4 IL10
9
Inflammatory bowel disease signaling 74
Show member pathways
 11.4 IL5 IL4 IL10
10
Th2 Differentiation 65
11.22 IL5 IL4 IL10 CD4
11
Inflammatory response pathway 74
11.13 IL4 IL5 THBS3
12
Immune infiltration in pancreatic cancer 74
11.01 IL5 IL4 IL10
13
OX40 Pathway 64
10.96 IL5 IL4 IL10
14
Innate Lymphoid Cells Differentiation 65
10.92 IL5 IL4 IL10 CD8A CD4
15
Selective expression of chemokine receptors during T-cell polarization 74
10.74 IL4 CD4
16
Cytokines and inflammatory response 74
10.72 IL5 IL4 IL10 CD4
17
IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types 65
10.63 IL5 IL4
18
Phase I biotransformations, non P450 74
Show member pathways
 10.57 CES2 CES1
Sources

GO Terms for Alveolar Echinococcosis

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Cellular components related to Alveolar Echinococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 respirasome GO:0070469 8.8 MT-ND2 MT-ND1 MT-CO1

Biological processes related to Alveolar Echinococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 T cell activation GO:0042110 9.73 IL4 CD8A CD4
2 type 2 immune response GO:0042092 9.46 IL4 IL10
3 regulation of isotype switching GO:0045191 9.26 IL4 IL10
4 positive regulation of immunoglobulin production GO:0002639 9.1 IL5 IL10 GPI

Molecular functions related to Alveolar Echinococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.76 IL5 IL4 IL10 GPI
2 methylumbelliferyl-acetate deacetylase activity GO:0047374 9.26 CES2 CES1
3 methyl indole-3-acetate esterase activity GO:0080030 8.62 CES2 CES1
Sources

Sources for Alveolar Echinococcosis

About this section
2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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