MCID: ALV001
MIFTS: 31

Alveolar Periostitis

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Alveolar Periostitis

MalaCards integrated aliases for Alveolar Periostitis:

Name: Alveolar Periostitis 12 15 71
Dry Socket 12 43
Alveolitis of Jaw 12
Alveolar Pyorrhea 71
Dry Tooth Socket 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13585
ICD9CM 34 526.5
MeSH 43 D004368
SNOMED-CT 67 12033006 61804006
ICD10 32 K10.3 M27.3
UMLS 71 C0013240 C0034219

Summaries for Alveolar Periostitis

MalaCards based summary : Alveolar Periostitis, also known as dry socket, is related to bone inflammation disease and rapidly involuting congenital hemangioma, and has symptoms including oral manifestations An important gene associated with Alveolar Periostitis is OAF (Out At First Homolog). The drugs Amoxicillin and Clavulanate have been mentioned in the context of this disorder. Affiliated tissues include bone, salivary gland and bone marrow.

Related Diseases for Alveolar Periostitis

Graphical network of the top 20 diseases related to Alveolar Periostitis:



Diseases related to Alveolar Periostitis

Symptoms & Phenotypes for Alveolar Periostitis

UMLS symptoms related to Alveolar Periostitis:


oral manifestations

Drugs & Therapeutics for Alveolar Periostitis

Drugs for Alveolar Periostitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 56)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
2
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
3
Ethanol Approved Phase 4 64-17-5 702
4 Anti-Infective Agents Phase 4
5 Antibiotics, Antitubercular Phase 4
6 Anti-Bacterial Agents Phase 4
7 Antiparasitic Agents Phase 4
8 Antiprotozoal Agents Phase 4
9 Amoxicillin-Potassium Clavulanate Combination Phase 4
10 beta-Lactamase Inhibitors Phase 4
11 Antitubercular Agents Phase 4
12 Renal Agents Phase 4
13 Bifidobacterium Phase 4
14 Anti-Infective Agents, Urinary Phase 4
15 Lactoferrin Phase 4
16 Sulfalene Phase 4
17 Antimalarials Phase 4
18
Lidocaine Approved, Vet_approved Phase 1, Phase 2 137-58-6 3676
19
Hyaluronic acid Approved, Vet_approved Phase 2 9004-61-9 53477741
20
Hydrogen peroxide Approved, Vet_approved Phase 2 7722-84-1 784
21 Octenidine Investigational Phase 2 71251-02-0
22 Anti-Infective Agents, Local Phase 2
23 Anesthetics Phase 1, Phase 2
24 Pharmaceutical Solutions Phase 2
25 sodium fluoride Approved 7681-49-4
26
Triclosan Approved, Investigational 3380-34-5 5564
27
Tetracycline Approved, Vet_approved 60-54-8 5353990
28
Peppermint oil Approved, Investigational 8006-90-4
29
Tocopherol Approved, Investigational 1406-66-2, 54-28-4 14986
30
Silicon Approved, Investigational 7440-21-3 4082203
31
Menthol Approved 2216-51-5 16666
32
Sorbitol Approved 50-70-4 5780
33
Peppermint Approved
34
Metronidazole Approved 443-48-1 4173
35
Vitamin C Approved, Nutraceutical 50-81-7 5785 54670067
36
Vitamin E Approved, Nutraceutical, Vet_approved 59-02-9 14985
37 Tocotrienol Investigational 6829-55-6
38 Fluorides
39 Hypolipidemic Agents
40 Protective Agents
41 Listerine
42 Lipid Regulating Agents
43 Cariostatic Agents
44 Antimetabolites
45 Propolis
46 Tocopherols
47 Fluorophosphate
48 Tocotrienols
49 Bee Products
50 Cardiac Glycosides

Interventional clinical trials:

(show all 16)
# Name Status NCT ID Phase Drugs
1 Efficacy of DC071 Mouthwash (0.2% Chlorhexidine Digluconate) in Peri-surgical Care for Preventing Alveolar Osteitis After Third Molar Extraction Completed NCT02382809 Phase 4 DC071;Placebo
2 Antibiotic Therapy in Erupted Tooth Extractions Completed NCT04082598 Phase 4 Amoxicillin Clavulanate
3 Examination of the Prevention and Treatment Modalities of Alveolitis in Relation With Impacted Teeth Surgery Recruiting NCT03741894 Phase 4 Iodoform;Chlorhexidine
4 Antibiotic Efficacy in Third Molar Surgery Completed NCT00118820 Phase 3 IV Preoperative antibiotic or placebo
5 The Influence of Intra-alveolar Application of Honey on Healing Following Molar Teeth Extraction: A Randomized Clinical Trial Unknown status NCT02678104 Phase 2 Chlorhexidine mouth wash;Intra-alveolar application of Manuka Honey
6 "Prevention of Dry Socket by Means of Single Preoperative Oral Dose of Metronidazole and Amoxicillin Compared to Conventional Therapy" Completed NCT03992144 Phase 2 Amoxicillin 500 Mg;metronidazole 400mg;metronidazol 400mg and amoxicillin 500mg
7 Does a Single Dose of Systemic Antibiotics Prevent Postoperative Inflammatory Complications After Lower Third Molar Surgery? A Randomized Controlled Trial Completed NCT03130933 Phase 1, Phase 2 Amoxicillin 500 Mg
8 Multi-centre, Open-label, First-in-man Study of Adult Patients Suffered From Alveolar Osteitis Treated Using Stomatological Tamponade Contipro Completed NCT04091399 Phase 2 Stamatological tamponade Contipro
9 Multicentre, Double-blind, Placebo-controlled, Randomized, Parallel Group Comparison of the Analgesic Effects of Different Maxigesic Doses Versus Acetaminophen, Ibuprofen and Placebo for the Teeth Extraction Pain Withdrawn NCT01104844 Phase 2 Full Dose Strength;Quarter dose strength;Half dose strength;Acetaminophen standard dose;Ibuprofen low dose;Ibuprofen high dose;Placebo
10 Effect of a Triclosan Containing Dentifrice on Oral Bacteria and Postoperative Complications Following Third Molar Surgery Completed NCT01292343
11 A Tetracycline Drain Reduces Alveolar Osteitis in Third Molar Surgery Completed NCT03494972 Tetracyclin ointment
12 Effect of NBF Gingival Gel Application in Controlling Post-surgical Complications After Impacted Lower Third Molar Surgery Completed NCT03641482 NBF
13 Effect of Concentrated Growth Factors on Frequency of Alveolar Osteitis Following Partially Erupted Mandibular Third Molar Surgery: A Randomized Controlled Clinical Study Completed NCT04151147
14 Post-extraction Wound Healing in Patients With Type 2 Diabetes Completed NCT01091909
15 Clinical Outcome of Dental Extractions Among Renal Transplant Recipients Completed NCT02547753
16 A Comparison of Single Preoperative Dose of Co-amoxiclav Versus Postoperative Full Course of Amoxicillin/ Co-amoxiclav in Prevention of Postoperative Complications in Dentoalveolar Surgery: a Randomized Controlled Trial Not yet recruiting NCT03844776 Co-Amoxiclav;Paracetamol;Chlorhexidine mouthwash;Normal saline;Amoxicillin 500 Mg;Metronidazole

Search NIH Clinical Center for Alveolar Periostitis

Cochrane evidence based reviews: dry socket

Genetic Tests for Alveolar Periostitis

Anatomical Context for Alveolar Periostitis

MalaCards organs/tissues related to Alveolar Periostitis:

40
Bone, Salivary Gland, Bone Marrow, Skin

Publications for Alveolar Periostitis

Articles related to Alveolar Periostitis:

(show top 50) (show all 370)
# Title Authors PMID Year
1
Infectious postoperative complications in oral surgery. An observational study. 61
31976046 2020
2
Evaluation of the effects of intra-alveolar irrigation with clindamycin, rifampicin and sterile saline in alveolar osteitis treatment. 61
31991214 2020
3
Retraction: Is treatment with platelet-rich fibrin better than zinc oxide eugenol in cases of established dry socket for controlling pain, reducing inflammation, and improving wound healing? 61
31966985 2019
4
A metagenomic study of patients with alveolar osteitis after tooth extraction. A preliminary case-control study. 61
30937543 2019
5
Efficacy of plasma rich in growth factor used for dry socket management: a systematic review. 61
31655828 2019
6
The influence of intra-alveolar application of honey versus Chlorhexidine rinse on the incidence of Alveolar Osteitis following molar teeth extraction. A randomized clinical parallel trial. 61
31636855 2019
7
Comparative Analysis of Blood Clot, Plasma Rich in Growth Factors and Platelet-Rich Fibrin Resistance to Bacteria-Induced Fibrinolysis. 61
31500263 2019
8
High-Throughput Sequencing Analysis of Microbial Profiles in the Dry Socket. 61
30946809 2019
9
Complications of Third Molar Extraction: A retrospective study from a tertiary healthcare centre in Oman. 61
31728221 2019
10
Post-extraction pain in the adjacent tooth after surgical extraction of the mandibular third molar. 61
31501778 2019
11
Mining Electronic Dental Records to Identify Dry Socket Risk Factors. 61
31349334 2019
12
Difflam™ mouthwash for dry socket. 61
30898457 2019
13
Is treatment with platelet-rich fibrin better than zinc oxide eugenol in cases of established dry socket for controlling pain, reducing inflammation, and improving wound healing? 61
31106135 2019
14
Guaiacol/β-cyclodextrin for rapid healing of dry socket: antibacterial activity, cytotoxicity, and bone repair-an animal study. 61
30737608 2019
15
Completeness of Electronic Dental Records in a Student Clinic: Retrospective Analysis. 61
30896435 2019
16
Are coronectomy studies being cited? A bibliometric study. 61
30324744 2019
17
A Comparative Evaluation of the Effectiveness of Chitosan-Based Dressing and Conventional Method of Hemostasis in Patients on Oral Antithrombotic Therapy without Therapy Interruption. 61
30923426 2019
18
[Alveolar osteitis treatment using Holisal gel]. 61
31922512 2019
19
A Study to Evaluate the Efficacy of Honey in the Management of Dry Socket. 61
32015642 2019
20
[Does chlorhexidine work as a preventive treatment for dry socket?] 61
30636260 2019
21
Extensive subcutaneous emphysema, pneumomediastinum, and pneumorrhachis following third molar surgery. 61
29752202 2018
22
Alveolar Osteitis: Patient's Compliance with Post-extraction Instructions Following Permanent Teeth Extraction. 61
30713183 2018
23
Novel Application of Platelet-Rich Fibrin as a Wound Healing Enhancement in Extraction Sockets of Patients Who Smoke. 61
30277951 2018
24
Common risk factors of dry socket (alveolitis osteitis) following dental extraction: A brief narrative review. 61
29723658 2018
25
Persistent socket pain postenucleation and post evisceration: a systematic review. 61
29633581 2018
26
Comparison of Surgical Outcome after Impacted Third Molar Surgery Using Piezotome and a Conventional Rotary Handpiece. 61
30294165 2018
27
Versatility of platelet rich fibrin in the management of alveolar osteitis-A clinical and prospective study. 61
30191106 2018
28
Magnetic ocular prosthesis for shallow contracted socket. 61
30127178 2018
29
Comparison of Envelope and Modified Triangular Flaps on Incidence of Dry Socket after Surgical Removal of Impacted Mandibular Third Molars: A Double-blind, Split-mouth Study. 61
30066688 2018
30
Efficacy of Alvogyl (Combination of Iodoform + Butylparaminobenzoate) and Zinc Oxide Eugenol for Dry Socket. 61
30693231 2018
31
Infection, Alveolar Osteitis, and Adverse Effects Using Metronidazole in Healthy Patients Undergoing Third Molar Surgery: A Meta-analysis. 61
29618877 2018
32
Angiogenesis and the prevention of alveolar osteitis: a review study. 61
29963489 2018
33
An unusual microscopic pattern of foreign body reaction as a complication of dry socket management. 61
29104032 2018
34
The efficacy of 1% Betadine mouthwash on the incidence of dry socket after mandibular third molar surgery. 61
29849968 2018
35
Dry Socket Etiology, Diagnosis, and Clinical Treatment Techniques. 61
29732309 2018
36
Prospective clinical study comparing intraligamentary anesthesia and inferior alveolar nerve block for extraction of posterior mandibular teeth. 61
29034443 2018
37
Role of turmeric in management of alveolar osteitis (dry socket): A randomised clinical study. 61
29556463 2018
38
Postoperative interventions to reduce inflammatory complications after third molar surgery: review of the current evidence. 61
28498604 2017
39
An evaluation of effects of platelet-rich-fibrin on postoperative morbidities after lower third molar surgery. 61
29378982 2017
40
Platelet-rich Plasma and Incidence of Alveolar Osteitis in High-risk Patients Undergoing Extractions of Mandibular Molars: A Case-control Study. 61
29284959 2017
41
Efficacy of different methods used for dry socket prevention and risk factor analysis: A systematic review. 61
29053647 2017
42
Effectiveness of platelet-rich fibrin in the management of pain and delayed wound healing associated with established alveolar osteitis (dry socket). 61
29279679 2017
43
Increasing popularity of waterpipe tobacco smoking and electronic cigarette use: Implications for oral healthcare. 61
28393367 2017
44
A novel method in the removal of impacted mandibular third molar: buccal drainage. 61
28974709 2017
45
How effective is collagen resorbable membrane placement after partially impacted mandibular third molar surgery on postoperative morbidity? A prospective randomized comparative study. 61
28982352 2017
46
Concomitant "Ear Bleed and Styloid Fracture": An Unusual Complication of Impacted Mandibular Third Molar Removal. 61
28751946 2017
47
Evaluation of the Need for Antibiotic Prophylaxis During Routine Intra-alveolar Dental Extractions in Healthy Patients: A Randomized Double-Blind Controlled Trial. 61
28865815 2017
48
Antibiotic treatment to prevent postextraction complications: a monocentric, randomized clinical trial. Preliminary outcomes. 61
28569454 2017
49
Influence of Qualification and Practice Settings of Dental Practitioners on Antimicrobial Prescribing in Delhi and National Capital Region, India. 61
28781493 2017
50
Comparative Study to Determine the efficacy of Zinc Oxide Eugenol and Alveogyl in Treatment of Dry Socket. 61
30353893 2017

Variations for Alveolar Periostitis

Expression for Alveolar Periostitis

Search GEO for disease gene expression data for Alveolar Periostitis.

Pathways for Alveolar Periostitis

GO Terms for Alveolar Periostitis

Cellular components related to Alveolar Periostitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Golgi lumen GO:0005796 9.16 OMD BGLAP
2 platelet alpha granule lumen GO:0031093 8.96 PLG PF4
3 collagen-containing extracellular matrix GO:0062023 8.8 PLG PF4 OMD

Biological processes related to Alveolar Periostitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of bone mineralization GO:0030500 8.62 BGLAP OMD

Sources for Alveolar Periostitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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