MCID: ALV003
MIFTS: 31

Alveoli Adenoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Alveoli Adenoma

MalaCards integrated aliases for Alveoli Adenoma:

Name: Alveoli Adenoma 12 15
Alveolar Adenoma 12 74
Adenoma of the Alveoli 12
Adenoma of Alveoli 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8003
NCIt 51 C4140
SNOMED-CT 69 8097004
UMLS 74 C0334303

Summaries for Alveoli Adenoma

MalaCards based summary : Alveoli Adenoma, also known as alveolar adenoma, is related to adenoma and lymphatic malformations. An important gene associated with Alveoli Adenoma is MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1), and among its related pathways/superpathways are VEGF Pathway (Tocris) and Angiogenesis (CST). Affiliated tissues include lung and whole blood, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Alveoli Adenoma

Diseases related to Alveoli Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 adenoma 10.5
2 lymphatic malformations 10.4 FLT4 PROX1
3 hemangioendothelioma 10.3 FLT4 PECAM1
4 solid adenocarcinoma with mucin production 10.3 KRT7 NKX2-1
5 ovarian germ cell teratoma 10.3 KRT7 NKX2-1
6 lung acinar adenocarcinoma 10.3 KRT7 NKX2-1
7 small cell carcinoma of the bladder 10.3 KRT7 NKX2-1
8 ovarian germ cell cancer 10.3 KRT7 NKX2-1
9 papillary adenoma 10.3 KRT7 NKX2-1
10 skin hemangioma 10.3 FLT1 PROX1
11 papillary serous adenocarcinoma 10.3 KRT7 NKX2-1
12 intestinal perforation 10.3 KRT7 NKX2-1
13 pulmonary sclerosing hemangioma 10.2 KRT7 NKX2-1
14 sclerosing hemangioma 10.2 KRT7 NKX2-1
15 lung adenoid cystic carcinoma 10.2 KRAS NKX2-1
16 duodenum adenocarcinoma 10.2 KRAS KRT7
17 mucinous bronchioloalveolar adenocarcinoma 10.2 KRT7 NKX2-1
18 appendix disease 10.2 KRAS KRT7
19 hobnail hemangioma 10.2 CD34 FLT4
20 nasal cavity adenocarcinoma 10.2 KRAS KRT7
21 pleomorphic carcinoma 10.2 KRT7 NKX2-1
22 malignant epithelioid hemangioendothelioma 10.2 CD34 FLT4
23 respiratory system benign neoplasm 10.2 KRAS NKX2-1
24 anal canal adenocarcinoma 10.2 KRAS KRT7
25 capillary hemangioma 10.2 FLT1 PECAM1
26 choreatic disease 10.2 NKX2-1 TBP
27 glomeruloid hemangioma 10.2 CD34 FLT1
28 vulvar sarcoma 10.2 CD34 KRT7
29 hydrocele 10.2 FLT4 PECAM1
30 pulmonary blastoma 10.2 KRAS NKX2-1
31 hennekam syndrome 10.1 FLT4 PROX1
32 eccrine adenocarcinoma 10.1 CD34 KRT7
33 erythema elevatum diutinum 10.1 CD34 PECAM1
34 biliary papillomatosis 10.1 KRAS KRT7
35 atypical choroid plexus papilloma 10.1 KRT7 NKX2-1
36 cavernous hemangioma 10.1 KRT7 NKX2-1 PECAM1
37 lymphangiosarcoma 10.1 CD34 FLT4 PROX1
38 mucinous adenocarcinoma 10.1 KRAS KRT7 NKX2-1
39 bronchiolo-alveolar adenocarcinoma 10.1 KRAS KRT7 NKX2-1
40 adenosquamous carcinoma 10.1 KRAS KRT7 NKX2-1
41 cystic teratoma 10.0 KRT7 NKX2-1
42 renal cell carcinoma, nonpapillary 10.0 FLT1 FLT4 KRT7 NKX2-1
43 cell type benign neoplasm 10.0 CD34 KRAS KRT7
44 gastrointestinal system cancer 10.0 CD34 KRAS KRT7
45 lung benign neoplasm 9.9 KRAS KRT7 NKX2-1 SCGB1A1
46 adenocarcinoma 9.9
47 interstitial emphysema 9.9 CD34 FLT1 FLT4 PROX1
48 vascular cancer 9.9 CD34 FLT1 FLT4 PROX1
49 ovarian cystic teratoma 9.9 KRT7 NKX2-1
50 kaposiform hemangioendothelioma 9.9 CD34 FLT4 PECAM1 PROX1

Graphical network of the top 20 diseases related to Alveoli Adenoma:



Diseases related to Alveoli Adenoma

Symptoms & Phenotypes for Alveoli Adenoma

MGI Mouse Phenotypes related to Alveoli Adenoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.86 FLT1 FLT4 KRAS MIB1 NKX2-1 PECAM1
2 homeostasis/metabolism MP:0005376 9.7 CD34 FLT1 FLT4 KRAS KRT7 MIB1
3 digestive/alimentary MP:0005381 9.63 FLT4 KRAS MIB1 NKX2-1 PECAM1 PROX1
4 normal MP:0002873 9.17 FLT1 FLT4 KRAS MIB1 NKX2-1 PROX1

Drugs & Therapeutics for Alveoli Adenoma

Search Clinical Trials , NIH Clinical Center for Alveoli Adenoma

Genetic Tests for Alveoli Adenoma

Anatomical Context for Alveoli Adenoma

MalaCards organs/tissues related to Alveoli Adenoma:

42
Lung, Whole Blood

Publications for Alveoli Adenoma

Articles related to Alveoli Adenoma:

(show all 29)
# Title Authors Year
1
Malignant transformation of alveolar adenoma to papillary adenocarcinoma: a case report. ( 27162700 )
2016
2
mRNAs and miRNAs in whole blood associated with lung hyperplasia, fibrosis, and bronchiolo-alveolar adenoma and adenocarcinoma after multi-walled carbon nanotube inhalation exposure in mice. ( 25926378 )
2016
3
Coexistence of lung alveolar adenoma with cerebral arteriovenous malformations: A case report and literature review. ( 26171008 )
2015
4
Cystic alveolar adenoma: an unusual clinical presentation of a rare lung neoplasm. ( 25474515 )
2015
5
Alveolar adenoma resected by thoracoscopic surgery. ( 24200660 )
2013
6
Alveolar adenoma combined with multifocal cysts: case report and literature review. ( 23653367 )
2013
7
Alveolar adenoma: an extremely rare innocent coin lesion. ( 22159242 )
2012
8
Alveolar adenoma of the lung: unusual diagnosis of a lesion positive on PET scan. A case report. ( 22214375 )
2012
9
CD34 Expression in the Stromal Cells of Alveolar Adenoma. ( 23118769 )
2012
10
Alveolar adenoma of the lung: a case report. ( 21587134 )
2011
11
An unusual case of a microscopic alveolar adenoma coexisting with lung carcinoma: a case report and review of the literature. ( 21592362 )
2011
12
Giant alveolar adenoma causing severe dyspnoea. ( 20581577 )
2010
13
A small alveolar adenoma resected by thoracoscopic surgery. ( 19231437 )
2009
14
Cytologic features of pulmonary alveolar adenoma. ( 19068683 )
2008
15
Alveolar adenoma of the lung. Immunohistochemical and flow cytometric characteristics of two new cases and a review of the literature. ( 18184418 )
2007
16
Alveolar adenoma. ( 17273617 )
2006
17
Alveolar adenoma of the lung: a clinicopathological description of a case of this very unusual tumour. ( 16254114 )
2005
18
Alveolar adenoma of the lung: a clinicopathologic, immunohistochemical, and molecular study of an unusual case. ( 15173924 )
2004
19
Alveolar adenoma. ( 15511494 )
2004
20
Alveolar adenoma of the lung--a report of two cases. ( 14575424 )
2003
21
Alveolar adenoma: an unusual lung tumor. ( 17670064 )
2003
22
Alveolar adenoma of the lung: computed tomography and magnetic resonance imaging findings. ( 11956369 )
2002
23
Alveolar adenoma: a histochemical, immunohistochemical, and ultrastructural analysis of 17 cases. ( 10029443 )
1999
24
Pulmonary nodule caused by an alveolar adenoma of the lung. ( 9083522 )
1997
25
A nonbalanced translocation (10;16) demonstrated by FISH analysis in a case of alveolar adenoma of the lung. ( 8689607 )
1996
26
Alveolar adenoma of the lung: further characterization of this uncommon tumour. ( 8917711 )
1996
27
Bronchiolar-alveolar adenoma in a rhesus monkey (Macaca mulatta). ( 8053138 )
1994
28
Lymphangioma (or alveolar adenoma?) of the lung. ( 3666680 )
1987
29
Alveolar adenoma. ( 3759064 )
1986

Variations for Alveoli Adenoma

Expression for Alveoli Adenoma

Search GEO for disease gene expression data for Alveoli Adenoma.

Pathways for Alveoli Adenoma

Pathways related to Alveoli Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.25 FLT1 FLT4 KRAS
2 10.87 FLT1 FLT4 PECAM1 PROX1
3 10.77 FLT1 FLT4 KRAS

GO Terms for Alveoli Adenoma

Biological processes related to Alveoli Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood vessel morphogenesis GO:0048514 9.37 FLT1 FLT4
2 epithelial tube branching involved in lung morphogenesis GO:0060441 9.32 KRAS NKX2-1
3 vascular endothelial growth factor signaling pathway GO:0038084 9.26 FLT1 FLT4
4 lymph vessel development GO:0001945 9.16 FLT4 PROX1
5 lymphangiogenesis GO:0001946 8.96 FLT4 PROX1
6 glomerular endothelium development GO:0072011 8.62 CD34 PECAM1

Molecular functions related to Alveoli Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear receptor binding GO:0016922 8.96 BAZ2A PROX1
2 vascular endothelial growth factor-activated receptor activity GO:0005021 8.62 FLT1 FLT4

Sources for Alveoli Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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