MCID: ALV003
MIFTS: 33

Alveoli Adenoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Alveoli Adenoma

MalaCards integrated aliases for Alveoli Adenoma:

Name: Alveoli Adenoma 12 15
Alveolar Adenoma 12 73
Adenoma of the Alveoli 12
Adenoma of Alveoli 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8003
NCIt 50 C4140
SNOMED-CT 68 8097004
UMLS 73 C0334303

Summaries for Alveoli Adenoma

MalaCards based summary : Alveoli Adenoma, also known as alveolar adenoma, is related to lymphangioma and adenoma. An important gene associated with Alveoli Adenoma is MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1), and among its related pathways/superpathways are AKT Signaling Pathway and Angiogenesis (CST). Affiliated tissues include lung, skin and liver, and related phenotypes are growth/size/body region and homeostasis/metabolism

Related Diseases for Alveoli Adenoma

Diseases related to Alveoli Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 97)
# Related Disease Score Top Affiliating Genes
1 lymphangioma 29.8 FLT4 HBA1 PROX1
2 adenoma 10.5
3 lymphatic malformations 10.3 FLT4 PROX1
4 capillary lymphangioma 10.2 HBA1 PROX1
5 acquired hemangioma 10.2 HBA1 PROX1
6 angiokeratoma of fordyce 10.2 HBA1 PROX1
7 solid adenocarcinoma with mucin production 10.2 KRT7 NKX2-1
8 ovarian germ cell teratoma 10.2 KRT7 NKX2-1
9 lung acinar adenocarcinoma 10.2 KRT7 NKX2-1
10 small cell carcinoma of the bladder 10.2 KRT7 NKX2-1
11 ovarian germ cell cancer 10.2 KRT7 NKX2-1
12 papillary adenoma 10.2 KRT7 NKX2-1
13 papillary serous adenocarcinoma 10.2 KRT7 NKX2-1
14 hennekam syndrome 10.2 FLT4 PROX1
15 intestinal perforation 10.2 KRT7 NKX2-1
16 pulmonary sclerosing hemangioma 10.2 KRT7 NKX2-1
17 sclerosing hemangioma 10.2 KRT7 NKX2-1
18 choreatic disease 10.2 NKX2-1 TBP
19 adenomatoid tumor 10.2 KRT7 NKX2-1
20 benign mesothelioma 10.2 HBA1 KRT7
21 adenoid squamous cell carcinoma 10.2 HBA1 KRT7
22 mucinous bronchioloalveolar adenocarcinoma 10.2 KRT7 NKX2-1
23 pleomorphic carcinoma 10.2 KRT7 NKX2-1
24 lung adenoid cystic carcinoma 10.2 KRAS NKX2-1
25 malignant epithelioid hemangioendothelioma 10.2 CD34 FLT4
26 duodenum adenocarcinoma 10.2 KRAS KRT7
27 appendix disease 10.1 KRAS KRT7
28 chondroid lipoma 10.1 HBA1 KRT7
29 capillary hemangioma 10.1 FLT1 HBA1
30 respiratory system benign neoplasm 10.1 KRAS NKX2-1
31 atypical choroid plexus papilloma 10.1 KRT7 NKX2-1
32 nasal cavity adenocarcinoma 10.1 KRAS KRT7
33 anal canal adenocarcinoma 10.1 KRAS KRT7
34 pulmonary blastoma 10.1 KRAS NKX2-1
35 skin epithelioid hemangioma 10.1 CD34 HBA1
36 ovary sarcoma 10.1 CD34 HBA1
37 cystic teratoma 10.1 KRT7 NKX2-1
38 ovarian angiosarcoma 10.1 CD34 HBA1
39 intravascular fasciitis 10.1 CD34 HBA1
40 pediatric angiosarcoma 10.1 CD34 HBA1
41 thyroid angiosarcoma 10.1 CD34 HBA1
42 spleen angiosarcoma 10.1 CD34 HBA1
43 vulvar sarcoma 10.1 CD34 KRT7
44 ovarian cystic teratoma 10.1 KRT7 NKX2-1
45 bone epithelioid hemangioma 10.1 CD34 HBA1
46 thyroid sarcoma 10.1 CD34 HBA1
47 hordeolum 10.1 CD34 HBA1
48 eccrine adenocarcinoma 10.1 CD34 KRT7
49 horseshoe kidney 10.1 KRT7 NKX2-1
50 hemangioma of liver 10.1 CD34 HBA1

Graphical network of the top 20 diseases related to Alveoli Adenoma:



Diseases related to Alveoli Adenoma

Symptoms & Phenotypes for Alveoli Adenoma

MGI Mouse Phenotypes related to Alveoli Adenoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.81 FLT1 FLT4 KRAS MIB1 MTHFD2 NKX2-1
2 homeostasis/metabolism MP:0005376 9.65 CD34 FLT1 FLT4 KRAS KRT7 MIB1
3 normal MP:0002873 9.17 FLT1 FLT4 KRAS MIB1 NKX2-1 PROX1

Drugs & Therapeutics for Alveoli Adenoma

Search Clinical Trials , NIH Clinical Center for Alveoli Adenoma

Genetic Tests for Alveoli Adenoma

Anatomical Context for Alveoli Adenoma

MalaCards organs/tissues related to Alveoli Adenoma:

41
Lung, Skin, Liver, Bone, Ovary, Spleen, Thyroid

Publications for Alveoli Adenoma

Articles related to Alveoli Adenoma:

(show all 29)
# Title Authors Year
1
Malignant transformation of alveolar adenoma to papillary adenocarcinoma: a case report. ( 27162700 )
2016
2
mRNAs and miRNAs in whole blood associated with lung hyperplasia, fibrosis, and bronchiolo-alveolar adenoma and adenocarcinoma after multi-walled carbon nanotube inhalation exposure in mice. ( 25926378 )
2016
3
Coexistence of lung alveolar adenoma with cerebral arteriovenous malformations: A case report and literature review. ( 26171008 )
2015
4
Cystic alveolar adenoma: an unusual clinical presentation of a rare lung neoplasm. ( 25474515 )
2015
5
Alveolar adenoma resected by thoracoscopic surgery. ( 24200660 )
2013
6
Alveolar adenoma combined with multifocal cysts: case report and literature review. ( 23653367 )
2013
7
Alveolar adenoma: an extremely rare innocent coin lesion. ( 22159242 )
2012
8
Alveolar adenoma of the lung: unusual diagnosis of a lesion positive on PET scan. A case report. ( 22214375 )
2012
9
CD34 Expression in the Stromal Cells of Alveolar Adenoma. ( 23118769 )
2012
10
Alveolar adenoma of the lung: a case report. ( 21587134 )
2011
11
An unusual case of a microscopic alveolar adenoma coexisting with lung carcinoma: a case report and review of the literature. ( 21592362 )
2011
12
Giant alveolar adenoma causing severe dyspnoea. ( 20581577 )
2010
13
A small alveolar adenoma resected by thoracoscopic surgery. ( 19231437 )
2009
14
Cytologic features of pulmonary alveolar adenoma. ( 19068683 )
2008
15
Alveolar adenoma of the lung. Immunohistochemical and flow cytometric characteristics of two new cases and a review of the literature. ( 18184418 )
2007
16
Alveolar adenoma. ( 17273617 )
2006
17
Alveolar adenoma of the lung: a clinicopathological description of a case of this very unusual tumour. ( 16254114 )
2005
18
Alveolar adenoma of the lung: a clinicopathologic, immunohistochemical, and molecular study of an unusual case. ( 15173924 )
2004
19
Alveolar adenoma. ( 15511494 )
2004
20
Alveolar adenoma of the lung--a report of two cases. ( 14575424 )
2003
21
Alveolar adenoma: an unusual lung tumor. ( 17670064 )
2003
22
Alveolar adenoma of the lung: computed tomography and magnetic resonance imaging findings. ( 11956369 )
2002
23
Alveolar adenoma: a histochemical, immunohistochemical, and ultrastructural analysis of 17 cases. ( 10029443 )
1999
24
Pulmonary nodule caused by an alveolar adenoma of the lung. ( 9083522 )
1997
25
A nonbalanced translocation (10;16) demonstrated by FISH analysis in a case of alveolar adenoma of the lung. ( 8689607 )
1996
26
Alveolar adenoma of the lung: further characterization of this uncommon tumour. ( 8917711 )
1996
27
Bronchiolar-alveolar adenoma in a rhesus monkey (Macaca mulatta). ( 8053138 )
1994
28
Lymphangioma (or alveolar adenoma?) of the lung. ( 3666680 )
1987
29
Alveolar adenoma. ( 3759064 )
1986

Variations for Alveoli Adenoma

Expression for Alveoli Adenoma

Search GEO for disease gene expression data for Alveoli Adenoma.

Pathways for Alveoli Adenoma

Pathways related to Alveoli Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.65 FLT1 FLT4 KRAS
2 11.28 FLT1 FLT4 PROX1
3
Show member pathways
11.05 FLT1 FLT4 KRAS
4
Show member pathways
10.46 FLT1 FLT4
5 10.42 FLT1 FLT4 KRAS

GO Terms for Alveoli Adenoma

Biological processes related to Alveoli Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood vessel morphogenesis GO:0048514 9.32 FLT1 FLT4
2 epithelial tube branching involved in lung morphogenesis GO:0060441 9.26 KRAS NKX2-1
3 vascular endothelial growth factor signaling pathway GO:0038084 9.16 FLT1 FLT4
4 lymph vessel development GO:0001945 8.96 FLT4 PROX1
5 lymphangiogenesis GO:0001946 8.62 FLT4 PROX1

Molecular functions related to Alveoli Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 vascular endothelial growth factor-activated receptor activity GO:0005021 8.62 FLT1 FLT4

Sources for Alveoli Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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