MCID: AML004
MIFTS: 34

Ameloblastic Carcinoma

Categories: Rare diseases, Oral diseases, Cancer diseases

Aliases & Classifications for Ameloblastic Carcinoma

MalaCards integrated aliases for Ameloblastic Carcinoma:

Name: Ameloblastic Carcinoma 53 59 73

Characteristics:

Orphanet epidemiological data:

59
ameloblastic carcinoma
Inheritance: Not applicable; Prevalence: <1/1000000 (Worldwide); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 59  
Rare odontological diseases


External Ids:

Orphanet 59 ORPHA314422
UMLS via Orphanet 74 C1314678
ICD10 via Orphanet 34 C41.1
UMLS 73 C1314678

Summaries for Ameloblastic Carcinoma

MalaCards based summary : Ameloblastic Carcinoma is related to adenoid cystic carcinoma and spitz nevus, and has symptoms including pain An important gene associated with Ameloblastic Carcinoma is MKI67 (Marker Of Proliferation Ki-67), and among its related pathways/superpathways are MicroRNAs in cancer and DNA Damage. Affiliated tissues include smooth muscle and lung, and related phenotypes are cellular and homeostasis/metabolism

Wikipedia : 76 Ameloblastic carcinoma is a rare form of odontogenic tumor, one that develops in the jawbones from the... more...

Related Diseases for Ameloblastic Carcinoma

Diseases related to Ameloblastic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 66)
# Related Disease Score Top Affiliating Genes
1 adenoid cystic carcinoma 29.1 KRT14 MKI67 TP63 VIM
2 spitz nevus 10.6 CDKN2A MKI67
3 oral leukoplakia 10.6 CDKN2A MKI67
4 cervical clear cell adenocarcinoma 10.6 CDKN2A KRT14
5 spiradenoma 10.6 KRT14 VIM
6 inverted papilloma 10.6 CDKN2A MKI67
7 odontoma 10.6 KRT14 VIM
8 basaloid squamous cell carcinoma 10.6 CDKN2A KRT14
9 malignant peritoneal mesothelioma 10.5 CDKN2A VIM
10 embryonal sarcoma 10.5 MKI67 VIM
11 pleomorphic liposarcoma 10.5 CDKN2A VIM
12 pre-malignant neoplasm 10.5 CDKN2A KRT14
13 endocervical adenocarcinoma 10.5 CDKN2A VIM
14 malignant fibroxanthoma 10.5 MKI67 VIM
15 intraneural perineurioma 10.4 KRT14 SLC2A1
16 cervical intraepithelial neoplasia 10.4 CDKN2A MKI67
17 chondromyxoid fibroma 10.4 CDKN2A VIM
18 hypohidrosis 10.4 KRT14 TP63
19 breast fibroadenoma 10.4 KRT14 MKI67
20 papillary thyroid microcarcinoma 10.4 MKI67 TP63
21 ameloblastoma 10.4
22 perineurioma 10.4 SLC2A1 VIM
23 in situ carcinoma 10.4 CDKN2A KRT14
24 limbal stem cell deficiency 10.4 KRT14 TP63
25 lipoadenoma 10.4 KRT14 TP63
26 syringoma 10.4 TP63 VIM
27 cervix small cell carcinoma 10.3 CDKN2A MAPK8IP2
28 pinguecula 10.3 KRT14 TP63
29 dermoid cyst 10.3 TP63 VIM
30 cellular schwannoma 10.3 CDKN2A SLC2A1
31 dystonia 11, myoclonic 10.3 SLC2A1 VIM
32 glomangioma 10.3 SLC2A1 VIM
33 skin benign neoplasm 10.3 KRT14 SLC2A1
34 cervix carcinoma 10.3 CDKN2A MAPK8IP2
35 intravascular papillary endothelial hyperplasia 10.3 HIF1A VIM
36 endometrial adenocarcinoma 10.2 CDKN2A MKI67
37 ependymoma 10.2 MKI67 VIM
38 craniopharyngioma 10.2 KRT14 MKI67
39 endometrial mucinous adenocarcinoma 10.2 CDKN2A MKI67 VIM
40 spindle cell carcinoma 10.2 TP63 VIM
41 gastrointestinal stromal tumor 10.2 CDKN2A MKI67 VIM
42 actinic keratosis 10.1 CDKN2A TP63
43 epidermodysplasia verruciformis 10.1 CDKN2A KRT14
44 mucoepidermoid carcinoma 10.1 KRT14 MKI67 TP63
45 necrotizing sialometaplasia 10.1 CDKN2A MKI67 TP63
46 meningioma, familial 10.1 MKI67 SLC2A1 VIM
47 mucinous bronchioloalveolar adenocarcinoma 10.1 CDKN2A SDC1
48 cervical squamous cell carcinoma 10.0 CDKN2A MKI67 TP63
49 benign breast phyllodes tumor 10.0 MKI67 TP63 VIM
50 hidradenocarcinoma 10.0 MKI67 TP63 VIM

Graphical network of the top 20 diseases related to Ameloblastic Carcinoma:



Diseases related to Ameloblastic Carcinoma

Symptoms & Phenotypes for Ameloblastic Carcinoma

UMLS symptoms related to Ameloblastic Carcinoma:


pain

MGI Mouse Phenotypes related to Ameloblastic Carcinoma:

46 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.04 VIM CDKN2A HIF1A KRT14 SDC1 SLC2A1
2 homeostasis/metabolism MP:0005376 10.03 CDKN2A HIF1A KRT14 MAPK8IP2 SDC1 SLC2A1
3 mortality/aging MP:0010768 9.97 CDKN2A HIF1A KRT14 MAPK8IP2 SDC1 SLC2A1
4 endocrine/exocrine gland MP:0005379 9.93 CDKN2A HIF1A KRT14 MAPK8IP2 SDC1 TP63
5 embryo MP:0005380 9.88 CDKN2A HIF1A SLC2A1 TP63 VIM
6 integument MP:0010771 9.8 CDKN2A HIF1A KRT14 SDC1 TP63
7 neoplasm MP:0002006 9.72 KRT14 SDC1 TP63 CDKN2A HIF1A
8 no phenotypic analysis MP:0003012 9.65 CDKN2A MAPK8IP2 MKI67 SLC2A1 TP63
9 reproductive system MP:0005389 9.63 CDKN2A KRT14 MAPK8IP2 SDC1 TP63 VIM
10 respiratory system MP:0005388 9.35 CDKN2A HIF1A KRT14 TP63 VIM
11 vision/eye MP:0005391 9.1 CDKN2A HIF1A KRT14 MAPK8IP2 TP63 VIM

Drugs & Therapeutics for Ameloblastic Carcinoma

Search Clinical Trials , NIH Clinical Center for Ameloblastic Carcinoma

Genetic Tests for Ameloblastic Carcinoma

Anatomical Context for Ameloblastic Carcinoma

MalaCards organs/tissues related to Ameloblastic Carcinoma:

41
Smooth Muscle, Lung

Publications for Ameloblastic Carcinoma

Articles related to Ameloblastic Carcinoma:

(show top 50) (show all 126)
# Title Authors Year
1
Ameloblastic Carcinoma In Situ: Review of Literature and a Case Presentation in a Pediatric Patient. ( 29715060 )
2018
2
Ameloblastic carcinoma with metastasis to the parotid gland. ( 29124909 )
2018
3
Literature review of 86 cases of mandibular ameloblastic carcinoma. ( 29937652 )
2018
4
Reconnoitre ameloblastic carcinoma: A prognostic update. ( 29362117 )
2018
5
Secondary Ameloblastic Carcinoma of Mandible with Pulmonary Metastasis. ( 29866242 )
2018
6
Recurrence and cancerization of ameloblastoma: multivariate analysis of 87 recurrent craniofacial ameloblastoma to assess risk factors associated with early recurrence and secondary ameloblastic carcinoma. ( 28729769 )
2017
7
Cervicopectoral flap as an adequate decision for advanced ameloblastic carcinoma. ( 28984029 )
2017
8
Pattern of care and impact of prognostic factors in the outcome of ameloblastic carcinoma: a systematic review and individual patient data analysis of 199 cases. ( 28600599 )
2017
9
A Rare Case Report of Spindle Cell Ameloblastic Carcinoma Involving the Mandible. ( 28274070 )
2017
10
Ameloblastic Carcinoma: A Rare Malignant Tumour in Maxillofacial Region. ( 28717298 )
2017
11
Immunohistochemical Expression of GLUT-1 and HIF-1I+ in Tooth Germ, Ameloblastoma, and Ameloblastic Carcinoma. ( 27020375 )
2016
12
Ameloblastic carcinoma (secondary type) with extensive squamous differentiation areas and dedifferentiated regions. ( 26768075 )
2016
13
Treatment of ameloblastoma and ameloblastic carcinoma with radiotherapy. ( 26796877 )
2016
14
Ameloblastic carcinoma of the maxilla: A case report and an updated review of the literature. ( 28105148 )
2016
15
Ameloblastic carcinoma of the maxilla: a report of two cases and a review of the literature. ( 26904494 )
2016
16
Ameloblastic Carcinoma: A Report of Three Cases. ( 27891485 )
2016
17
Immunohistochemical expression of K6, K8, K16, K17, K19, maspin, syndecan-1 (CD138), I+-SMA, and Ki-67 in ameloblastoma and ameloblastic carcinoma: diagnostic and prognostic correlations. ( 26972539 )
2016
18
Ameloblastic carcinoma: a Brazilian collaborative study of 17 cases. ( 27195964 )
2016
19
Ameloblastic Carcinoma: A Case Report. ( 26393226 )
2015
20
Primary ameloblastic carcinoma of the maxilla: A case report and literature review. ( 25436009 )
2015
21
Single-Fraction Helical Tomotherapy forA Ameloblastic Carcinoma. ( 26272005 )
2015
22
Spindle cell variant of ameloblastic carcinoma: a case report and literature review. ( 26238174 )
2015
23
Ameloblastic carcinoma of the mandible manifesting as an infected odontogenic cyst. ( 25574726 )
2015
24
Ameloblastic Carcinoma. ( 26126621 )
2015
25
Expression of the transcription factor PITX2 in ameloblastic carcinoma. ( 25791324 )
2015
26
Ameloblastic carcinoma: An effort to abridge this diagnostic challenge! ( 26853419 )
2015
27
Ameloblastic carcinoma with features of ghost cell odontogenic carcinoma in a patient with suspected Gardner syndrome. ( 25434693 )
2015
28
Spindle cell variant of ameloblastic carcinoma: a case report and review of literature. ( 25939122 )
2015
29
Spindle-cell ameloblastic carcinoma of the maxilla with adenoid cystic carcinoma-like areas: A new variant? ( 26549079 )
2015
30
Massive Skull Base Ameloblastic Carcinoma with Intracranial Extension. ( 27560532 )
2015
31
Immunoexpression of Ki-67, MCM2, and MCM3 in Ameloblastoma and Ameloblastic Carcinoma and Their Correlations with Clinical and Histopathological Patterns. ( 26823641 )
2015
32
Ameloblastic carcinoma: Report of a rare case. ( 24579073 )
2014
33
Ameloblastic carcinoma: An analysis of 12 cases with a review of the literature. ( 25013517 )
2014
34
Usefulness of (11)C-methionine positron emission tomography for detecting intracranial ameloblastic carcinoma: A case report. ( 25202358 )
2014
35
Evaluation of SOX2 as a potential marker for ameloblastic carcinoma. ( 24603057 )
2014
36
Ameloblastic carcinoma of the mandible: Report of a case and review. ( 25364189 )
2014
37
Ameloblastic carcinoma developing in preexisting ameloblastoma with a mutation of the p53 gene: a case report. ( 24906942 )
2014
38
Ameloblastic carcinoma: A clinicopathologic dilemma - Report of two cases with total review of literature from 1984 to 2012. ( 24987603 )
2014
39
Ameloblastic carcinoma of mandible: facts and dilemmas. ( 25343557 )
2014
40
Prominent response with helical tomotherapy in recurrent ameloblastic carcinoma of maxillary sinus: a case report. ( 25027948 )
2014
41
Identification of proteins with increased levels in ameloblastic carcinoma. ( 24485979 )
2014
42
A rare case of ameloblastic carcinoma. ( 25255357 )
2014
43
Ameloblastic carcinoma: A case series. ( 25210376 )
2014
44
Ameloblastic carcinoma of the mandible with clear cell changes: a case report. ( 23713037 )
2013
45
Treatment strategy of a huge ameloblastic carcinoma. ( 23348302 )
2013
46
Spindle cell ameloblastic carcinoma in a labrador retriever dog. ( 23229541 )
2013
47
Ameloblastic carcinoma, secondary type, of the mandible: a case report. ( 23099227 )
2013
48
Hypermethylation of p16 tumor-suppressor gene in ameloblastic carcinoma, ameloblastoma, and dental follicles. ( 22705216 )
2013
49
Large ameloblastic carcinoma: A rare case with management. ( 24379872 )
2013
50
The variability and complexity of ameloblastoma: carcinoma ex ameloblastoma or primary ameloblastic carcinoma. ( 22920533 )
2013

Variations for Ameloblastic Carcinoma

Expression for Ameloblastic Carcinoma

Search GEO for disease gene expression data for Ameloblastic Carcinoma.

Pathways for Ameloblastic Carcinoma

Pathways related to Ameloblastic Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.97 CDKN2A TP63 VIM
2 11.73 CDKN2A MKI67 TP63 VIM
3 10.82 HIF1A SLC2A1
4 10.53 CDKN2A HIF1A SLC2A1
5
Show member pathways
10.5 CDKN2A TP63

GO Terms for Ameloblastic Carcinoma

Biological processes related to Ameloblastic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 8.8 HIF1A SDC1 VIM

Molecular functions related to Ameloblastic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein domain specific binding GO:0019904 9.43 HIF1A TP63 VIM
2 protein C-terminus binding GO:0008022 9.33 MKI67 SDC1 VIM
3 transcription factor activity, transcription factor binding GO:0000989 8.96 HIF1A TP63
4 keratin filament binding GO:1990254 8.62 KRT14 VIM

Sources for Ameloblastic Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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