MCID: AMN015
MIFTS: 21

Amenorrhea-Galactorrhea Syndrome

Aliases & Classifications for Amenorrhea-Galactorrhea Syndrome

MalaCards integrated aliases for Amenorrhea-Galactorrhea Syndrome:

Name: Amenorrhea-Galactorrhea Syndrome 56
Non-Pregnancy Related a-G Syndrome 71
Forbes Albright Syndrome 71

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant


HPO:

31
amenorrhea-galactorrhea syndrome:
Inheritance autosomal dominant inheritance


External Ids:

OMIM 56 104600
MedGen 41 C0271556
UMLS 71 C0271556 C2931414

Summaries for Amenorrhea-Galactorrhea Syndrome

MalaCards based summary : Amenorrhea-Galactorrhea Syndrome, also known as non-pregnancy related a-g syndrome, is related to galactorrhea and amenorrhea. Affiliated tissues include pituitary, thyroid and breast, and related phenotypes are abnormality of the thorax and secondary amenorrhea

More information from OMIM: 104600

Related Diseases for Amenorrhea-Galactorrhea Syndrome

Diseases related to Amenorrhea-Galactorrhea Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
# Related Disease Score Top Affiliating Genes
1 galactorrhea 11.1
2 amenorrhea 11.1
3 hyperprolactinemia 10.6
4 adenoma 10.5
5 pituitary tumors 10.4
6 pituitary adenoma 10.4
7 sarcoidosis 1 10.3
8 hypothyroidism 10.3
9 acromegaly 10.3
10 hypopituitarism 10.3
11 diabetes insipidus 10.3
12 arachnoid cysts, intracranial 10.1
13 myxedema 10.1
14 pituitary adenoma, prolactin-secreting 10.1
15 secretory diarrhea 10.1
16 diarrhea 10.1
17 neurosarcoidosis 10.1
18 constipation 10.1
19 anovulation 10.1
20 chromophobe adenoma 10.1
21 craniopharyngioma 10.1
22 polyradiculoneuropathy 10.1
23 hyperthyroidism 10.1
24 hypoglycemia 10.1
25 thyroid ectopia 10.1

Graphical network of the top 20 diseases related to Amenorrhea-Galactorrhea Syndrome:



Diseases related to Amenorrhea-Galactorrhea Syndrome

Symptoms & Phenotypes for Amenorrhea-Galactorrhea Syndrome

Human phenotypes related to Amenorrhea-Galactorrhea Syndrome:

31
# Description HPO Frequency HPO Source Accession
1 abnormality of the thorax 31 HP:0000765
2 secondary amenorrhea 31 HP:0000869
3 pituitary adenoma 31 HP:0002893
4 galactorrhea 31 HP:0100829
5 large sella turcica 31 HP:0002690

Symptoms via clinical synopsis from OMIM:

56
Genitourinary Internal Genitalia Female:
secondary amenorrhea

Neoplasia:
pituitary adenoma

Skeletal Skull:
enlarged sella turcica

Endocrine Features:
secondary amenorrhea

Chest Breasts:
galactorrhea

Clinical features from OMIM:

104600

Drugs & Therapeutics for Amenorrhea-Galactorrhea Syndrome

Search Clinical Trials , NIH Clinical Center for Amenorrhea-Galactorrhea Syndrome

Genetic Tests for Amenorrhea-Galactorrhea Syndrome

Anatomical Context for Amenorrhea-Galactorrhea Syndrome

MalaCards organs/tissues related to Amenorrhea-Galactorrhea Syndrome:

40
Pituitary, Thyroid, Breast, Hypothalamus, Kidney, Pancreas, Testes

Publications for Amenorrhea-Galactorrhea Syndrome

Articles related to Amenorrhea-Galactorrhea Syndrome:

(show top 50) (show all 111)
# Title Authors PMID Year
1
[Prolactin adenoma in a irl whose mother had had a pituitary adenoma with amenorrhea-galactorrhea]. 56
4299353 1967
2
Spectrum of nonpuerperal galactorrhea: report of two cases evolving through the various syndromes. 56
6067055 1967
3
Hyperprolactinemia associated with macroprolactinoma in a 17-year-old: A case report. 61
31016137 2019
4
[Amenorrhea-galactorrhea syndrome]. 61
16817430 2006
5
Hypopituitarism and amenorrhea-galactorrhea syndrome caused by thrombosis of both internal carotid artery and giant intrasellar aneurysm: case report. 61
15122453 2004
6
Endocrine aspects of neurosarcoidosis. 61
12150344 2002
7
Amenorrhea-galactorrhea syndrome as an uncommon manifestation of isolated neurosarcoidosis. 61
11799635 2001
8
[Gonadotroph pituitary adenomas]. 61
10970952 2000
9
Spontaneous remission in idiopathic hyperprolactinemia. 61
11273299 1998
10
Two-step development of a pituitary adenoma: from hyperprolactinemic syndrome to Cushing's disease. 61
9211134 1997
11
[Normalization of the prolactin values during alfa-interferon therapy: the considerations with a female patient with anti-HCV-positive chronic hepatitis and prolactin-secreting hypophyseal microadenoma]. 61
8766348 1996
12
Primary amenorrhea-galactorrhea with hyperprolactinemia and huge pituitary enlargement in juvenile primary hypothyroidism. 61
1451896 1992
13
[Gonadotropic adenoma. Clinical and hormonal characteristics]. 61
2241082 1990
14
[Dysthyroidism in the post-partum period]. 61
2576153 1989
15
[Correlations between hyperprolactinemia and galactorrhea]. 61
2486966 1989
16
Acromegaly as the amenorrhea-galactorrhea syndrome. 61
2608212 1989
17
Hyperprolactinemia with prolonged amenorrhea reversed with bromocriptine in a menopausal woman. 61
3122579 1988
18
A combined anterior pituitary stimulation test: experience with 285 individuals. 61
3121862 1987
19
Pituitary adenoma composed of two compartments each secreting prolactin or growth hormone. 61
3614605 1987
20
[The physiopathological aspects of the normoprolactinemic amenorrhea-galactorrhea syndrome]. 61
3154362 1987
21
[Malignant neoplasm of the pituitary gland as a cause of the amenorrhea-galactorrhea syndrome]. 61
3617741 1987
22
Post-traumatic diabetes insipidus and amenorrhea-galactorrhea syndrome after pituitary stalk rupture. 61
3614629 1987
23
Carcinoid tumor of the pancreas causing the diarrheogenic syndrome: report of a case combined with multiple endocrine neoplasia, type I. 61
2867611 1986
24
Amenorrhea-galactorrhea syndrome in the prolactin-secreting pituitary tumor: nursing implications. 61
3850930 1985
25
[A case of treated primary sterility and the course of pregnancy in the amenorrhea-galactorrhea syndrome associated with pituitary adenoma and hyperprolactinemia]. 61
4016999 1985
26
Resolution of acromegaly, amenorrhea-galactorrhea syndrome, and hypergastrinemia after resection of jejunal carcinoid. 61
4038403 1985
27
[Acute transient Korsakoff's syndrome caused by hematoma of the floor of the 3rd ventricle]. 61
4012145 1985
28
Chronic dihydroergotoxine treatment affects the number of dopamine recognition sites in rat striatum. 61
6463097 1984
29
[Computed tomography of amenorrhea-galactorrhea syndrome]. 61
6541261 1984
30
Arachnoid cyst as a cause of the amenorrhea-galactorrhea syndrome. 61
6720781 1984
31
[Results of bromocriptine treatment of women with functional amenorrhea-galactorrhea syndrome]. 61
6510365 1984
32
Regression of a pituitary adenoma following levothyroxine therapy of primary hypothyroidism. 61
6411499 1983
33
[2 cases of Rathke's cleft cyst with amenorrhea-galactorrhea syndrome]. 61
6685588 1983
34
[Case of acute polyradiculoneuropathy with various autonomic symptoms and amenorrhea-galactorrhea syndrome]. 61
6686094 1983
35
Regression of pituitary tumor after thyroid replacement in primary hypothyroidism. 61
6682252 1983
36
[Amenorrhea-galactorrhea syndrome: clinical characteristics, prolactin secretion and estrogenic activity]. 61
6407903 1983
37
[Pathologic hyperprolactinemia. I. Positive diagnosis and etiology]. 61
6293080 1982
38
Diagnosis of pituitary tumors by hormone assays and computerized tomography. 61
7091157 1982
39
[Alphamethyldopa-induced hyperprolactinemia, amenorrhea, galactorrhea syndrome in chronic kidney failure]. 61
7202173 1982
40
Transsphenoidal microsurgery for prolactin-secreting pituitary adenomas. 61
7198681 1982
41
Multiple endocrine adenomatosis with Cushing's disease and the amenorrhea-galactorrhea syndrome responsive to proton beam irradiation. 61
6116287 1981
42
[Psychogenic factors in amenorrhea-galactorrhea syndrome]. 61
7199501 1981
43
[A case of craniopharyngioma with hyperprolactinemia in postoperative course (author's transl)]. 61
7242837 1981
44
Amenorrhea, galactorrhea, hyperprolactinemia syndrome and breast carcinoma in a young woman. 61
7194824 1981
45
[Pregnancy with thyroid replacement and additional bromocriptine therapy in a patient of amenorrhea-galactorrhea syndrome due to primary hypothyroidism (author's transl)]. 61
7234339 1981
46
[Puberty in congenital hypothyroidism (author's transl)]. 61
7469193 1980
47
Drug-induced alterations of the hypothalamus-hypophysis axis. 61
7234453 1980
48
Prolactin and growth hormone responses in the amenorrhea-galactorrhea syndrome. 61
7190256 1980
49
[Sulpiride amenorrhea-galactorrhea syndrome. Clinical contribution]. 61
7193270 1980
50
Partial or complete regression of hyperprolactinemic amenorrhea-galactorrhea syndrome after bromocriptine-induced pregnancy. 61
7208090 1980

Variations for Amenorrhea-Galactorrhea Syndrome

Expression for Amenorrhea-Galactorrhea Syndrome

Search GEO for disease gene expression data for Amenorrhea-Galactorrhea Syndrome.

Pathways for Amenorrhea-Galactorrhea Syndrome

GO Terms for Amenorrhea-Galactorrhea Syndrome

Sources for Amenorrhea-Galactorrhea Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
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34 ICD9CM
35 IUPHAR
36 KEGG
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43 MeSH
44 MESH via Orphanet
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48 NCI
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50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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