MCID: AMT001
MIFTS: 26

Ametropic Amblyopia

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Ametropic Amblyopia

MalaCards integrated aliases for Ametropic Amblyopia:

Name: Ametropic Amblyopia 12 15
Refractive Amblyopia 12 70

Classifications:



External Ids:

Disease Ontology 12 DOID:10377
ICD9CM 34 368.03
SNOMED-CT 67 90927000
ICD10 32 H53.02
UMLS 70 C0152190

Summaries for Ametropic Amblyopia

MalaCards based summary : Ametropic Amblyopia, also known as refractive amblyopia, is related to esotropia and anisometropia. An important gene associated with Ametropic Amblyopia is PHOX2A (Paired Like Homeobox 2A). The drugs Methamphetamine and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and cortex.

Wikipedia : 73 Ametropic amblyopia, is a medical condition in which the retina cannot focus on the image of a distant... more...

Related Diseases for Ametropic Amblyopia

Graphical network of the top 20 diseases related to Ametropic Amblyopia:



Diseases related to Ametropic Amblyopia

Symptoms & Phenotypes for Ametropic Amblyopia

Drugs & Therapeutics for Ametropic Amblyopia

Drugs for Ametropic Amblyopia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methamphetamine Approved, Illicit 537-46-2 10836
2
Dopamine Approved 51-61-6, 62-31-7 681
3 Central Nervous System Stimulants
4 Dopamine Agents
5 Dopamine Uptake Inhibitors
6 Neurotransmitter Agents
7 Sympathomimetics
8 Adrenergic Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Bilateral Refractive Amblyopia Treatment Study Completed NCT00305955
2 Objective Adherence With Optical Correction in Children With Bilateral and Unilateral Refractive Amblyopia Terminated NCT03780205

Search NIH Clinical Center for Ametropic Amblyopia

Genetic Tests for Ametropic Amblyopia

Anatomical Context for Ametropic Amblyopia

MalaCards organs/tissues related to Ametropic Amblyopia:

40
Eye, Retina, Cortex

Publications for Ametropic Amblyopia

Articles related to Ametropic Amblyopia:

(show top 50) (show all 137)
# Title Authors PMID Year
1
Characterising the orientation-specific pattern-onset visual evoked potentials in children with bilateral refractive amblyopia and non-amblyopic controls. 61
32968834 2021
2
Amblyopia screening effectiveness at 3-4 years old: a cohort study. 61
33437872 2021
3
Ophthalmic Abnormalities among Children Treated with Cochlear Implants. 61
33136008 2020
4
Prevalence and causes of visual impairment among hearing impaired students in Lagos, Nigeria. 61
33190026 2020
5
Visual outcomes after refractive laser corneal surgery and phakic IOL in amblyopic eyes. 61
32601965 2020
6
Saccadic reaction time and ocular findings in phenylketonuria. 61
32450880 2020
7
Effect of Stimulus Orientation on Visual Function in Children with Refractive Amblyopia. 61
32392311 2020
8
[The performance of visual photoscreening for Chinese preschool children aged 4 to 5 years]. 61
32187947 2020
9
Refractive Errors and Amblyopia Among Children Screened by the UCLA Preschool Vision Program in Los Angeles County. 61
31647932 2020
10
Positive predictive value and screening performance of GoCheck Kids in a primary care university clinic. 61
31940501 2020
11
Nanophthalmos in children: morphometric and clinical characterization. 61
32058088 2020
12
Correlation between higher-order aberrations and visual acuity recovery (CoHORT) after spectacles treatment for pediatric refractive amblyopia: A pilot study using iDesign measurement. 61
32059018 2020
13
Is amblyopia associated with school readiness and cognitive performance during early schooling? Findings from the Millennium Cohort Study. 61
32559208 2020
14
[Long-term functional outcomes after congenital cataract extraction with intraocular lens implantation in children of the first year of life]. 61
33371642 2020
15
[Factors influencing target refraction in children with pseudophakia after extraction of congenital cataract]. 61
32504483 2020
16
Quality of life and mental health in amblyopic children treated with and without occlusion therapy. 61
31678257 2019
17
Full time occlusion VS part time occlusion in treatment of monocular amblyopia. 61
31777509 2019
18
Evaluation of Metabolite Changes in the Occipital Cortex of Patients with Idiopathic Infantile Nystagmus or Bilateral Ametropic Amblyopia by Magnetic Resonance Spectroscopy. 61
31612650 2019
19
Ocular characteristics in a variant microcephalic primordial dwarfism type II. 61
31510961 2019
20
Zone of retinal vascularization and refractive error in premature eyes with and without spontaneously regressed retinopathy of prematurity. 61
31229607 2019
21
Amblyopia therapy in Asian children: factors affecting visual outcome and parents' perception of children's attitudes towards amblyopia treatment. 61
30488078 2019
22
Corneal indices following photorefractive keratectomy in children at least 5 years after surgery. 61
31103563 2019
23
Late Ophthalmologic Referral of Anisometropic Amblyopia: A Retrospective Study of Different Amblyopia Subtypes. 61
30946787 2019
24
Ocular findings in posterior microphthalmos. 61
30930662 2019
25
New advances in amblyopia therapy II: refractive therapies. 61
29871968 2018
26
Community outreach: An indicator for assessment of prevalence of amblyopia. 61
29941736 2018
27
New pediatric risk factors for amblyopia: strabismic versus refractive. 61
28967080 2018
28
Evaluation of a smartphone photoscreening app to detect refractive amblyopia risk factors in children aged 1-6 years. 61
30197499 2018
29
Ophthalmic findings in Frank-ter Haar syndrome: report of a sibling pair. 61
29100834 2017
30
[Acupuncture mainly with "guoyanre" manipulation for amblyopia in children]. 61
29354955 2017
31
Analysis of Macular and Retinal Nerve Fiber Layer Thickness in Children with Refractory Amblyopia after Femtosecond Laser-assisted Laser In situ Keratomileusis: A Retrospective Study. 61
28875960 2017
32
Benign Yellow Dot Maculopathy: A New Macular Phenotype. 61
28366503 2017
33
An Assessment of the Contrast Sensitivity in Patients with Ametropic and Anisometropic Amblyopia in Achieving the Corrected Visual Acuity of 1.0. 61
28169333 2017
34
Refractive Errors and Amblyopia in the UCLA Preschool Vision Program; First Year Results. 61
27640004 2016
35
Visual outcomes after spectacles treatment in children with bilateral high refractive amblyopia. 61
27426739 2016
36
OCT in a Myelinated Retinal Nerve Fiber Syndrome with Reduced Vision. 61
27529609 2016
37
Prevalence and pattern of amblyopia among primary school pupils in Kosofe town, Lagos state, Nigeria. 61
28000640 2016
38
Refractive Amblyopia among children in Ibadan: the need for amblyopia screening programmes. 61
27280236 2015
39
The incidence and visual acuity outcomes of children identified with ametropic amblyopia by vision screening. 61
25828821 2015
40
SCHOOL INTEGRATION FOR PATIENTS WITH AMBLYOPIA. 61
27373116 2015
41
Performance of the Plusoptix A09 photoscreener in detecting amblyopia risk factors in Chinese children attending an eye clinic. 61
26030210 2015
42
Impact of cylinder axis on the treatment for astigmatic amblyopia. 61
24384526 2014
43
Perceptual learning improves stereoacuity in amblyopia. 61
24508791 2014
44
Stereoscopic visual acuity in types of ametropic amblyopia in children. 61
24804304 2014
45
Comparison of surgically induced astigmatism in patients with horizontal rectus muscle recession. 61
25161948 2014
46
Corneal refractive surgery and phakic intraocular lens for treatment of amblyopia caused by high myopia or anisometropia in children. 61
24890172 2014
47
Isolated congenital hereditary cataract in a dizygotic twin: prenatal ultrasonographic diagnosis. 61
23931615 2013
48
Prevalence and etiology of amblyopia in Southern India: results from screening of school children aged 5-15 years. 61
23865603 2013
49
[Visual impairment and blindness in children in a Malawian school for the blind]. 61
23959513 2013
50
Regression of myelinated retinal nerve fibers in a glaucomatous eye. 61
23708924 2013

Variations for Ametropic Amblyopia

Expression for Ametropic Amblyopia

Search GEO for disease gene expression data for Ametropic Amblyopia.

Pathways for Ametropic Amblyopia

GO Terms for Ametropic Amblyopia

Biological processes related to Ametropic Amblyopia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of signaling receptor activity GO:2000272 8.96 MTRNR2L5 MTRNR2L4
2 negative regulation of execution phase of apoptosis GO:1900118 8.62 MTRNR2L5 MTRNR2L4

Molecular functions related to Ametropic Amblyopia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 receptor antagonist activity GO:0048019 8.62 MTRNR2L5 MTRNR2L4

Sources for Ametropic Amblyopia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....