MCID: AMT001
MIFTS: 27

Ametropic Amblyopia

Categories: Eye diseases

Aliases & Classifications for Ametropic Amblyopia

MalaCards integrated aliases for Ametropic Amblyopia:

Name: Ametropic Amblyopia 12 15
Refractive Amblyopia 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10377
ICD10 33 H53.02
ICD9CM 35 368.03
SNOMED-CT 68 90927000
UMLS 73 C0152190

Summaries for Ametropic Amblyopia

MalaCards based summary : Ametropic Amblyopia, also known as refractive amblyopia, is related to amblyopia and cornea plana. An important gene associated with Ametropic Amblyopia is SH3PXD2B (SH3 And PX Domains 2B). The drug Mydriatics has been mentioned in the context of this disorder. Affiliated tissues include retina, eye and occipital lobe.

Wikipedia : 76 Ametropic amblyopia, is a medical condition in which the retina cannot focus on the image of a distant... more...

Related Diseases for Ametropic Amblyopia

Diseases related to Ametropic Amblyopia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
# Related Disease Score Top Affiliating Genes
1 amblyopia 31.0 DPT CYLC1 CHN1
2 cornea plana 10.2
3 suppression amblyopia 10.2
4 esotropia 10.2
5 anisometropia 10.1 DPT CHN1
6 third cranial nerve disease 10.0 MTRNR2L4 CHN1
7 oculomotor nerve paralysis 10.0 MTRNR2L4 CHN1
8 xerophthalmia 10.0 GABBR1 CADM1
9 strabismus 10.0
10 accommodative esotropia 10.0
11 regular astigmatism 9.9 DPT CYLC1
12 paralytic squint 9.8 MTRNR2L5 GABBR1 CHN1 CADM1
13 disuse amblyopia 9.7 SDCBP DPT CHN1 CADM1
14 asthenopia 9.4 SDCBP MTRNR2L5 MTRNR2L4 GABBR1 CADM1

Graphical network of the top 20 diseases related to Ametropic Amblyopia:



Diseases related to Ametropic Amblyopia

Symptoms & Phenotypes for Ametropic Amblyopia

Drugs & Therapeutics for Ametropic Amblyopia

Drugs for Ametropic Amblyopia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Mydriatics Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Is Non-cycloplegic Photorefraction Applicable for Screening Refractive Risk Factors of Amblyopia? Completed NCT01308307 Phase 2
2 Bilateral Refractive Amblyopia Treatment Study Completed NCT00305955
3 Bilateral and Unilateral Amblyopia Treatment Study Recruiting NCT03780205

Search NIH Clinical Center for Ametropic Amblyopia

Genetic Tests for Ametropic Amblyopia

Anatomical Context for Ametropic Amblyopia

MalaCards organs/tissues related to Ametropic Amblyopia:

41
Retina, Eye, Occipital Lobe

Publications for Ametropic Amblyopia

Articles related to Ametropic Amblyopia:

(show all 30)
# Title Authors Year
1
Evaluation of a smartphone photoscreening app to detect refractive amblyopia risk factors in children aged 1-6 years. ( 30197499 )
2018
2
Visual outcomes after spectacles treatment in children with bilateral high refractive amblyopia. ( 27426739 )
2016
3
Refractive Amblyopia among children in Ibadan: the need for amblyopia screening programmes. ( 27280236 )
2015
4
The incidence and visual acuity outcomes of children identified with ametropic amblyopia by vision screening. ( 25828821 )
2015
5
Stereoscopic visual acuity in types of ametropic amblyopia in children. ( 24804304 )
2014
6
Interventions for unilateral and bilateral refractive amblyopia. ( 22513928 )
2012
7
Is noncycloplegic photorefraction applicable for screening refractive amblyopia risk factors? ( 22737380 )
2012
8
Photorefractive keratectomy in treatment of refractive amblyopia in the adult population. ( 22108111 )
2011
9
Paediatric hyperopia, accommodative esotropia and refractive amblyopia. ( 21198839 )
2011
10
Occipital lobe's cortical thinning in ametropic amblyopia. ( 19110391 )
2009
11
Treatment of bilateral refractive amblyopia in children three to less than 10 years of age. ( 18282498 )
2008
12
Interventions for unilateral refractive amblyopia. ( 18843683 )
2008
13
Treatment of bilateral refractive amblyopia in children three to less than 10 years of age. ( 17707330 )
2007
14
What's your diagnosis? Sporadic nanophthalmos (posterior microphthalmos), bilateral ametropic amblyopia, and esotropia. ( 16382555 )
2005
15
Remediation of refractive amblyopia by optical correction alone. ( 12162480 )
2002
16
Maintenance of improvement gains in refractive amblyopia: a comparison of treatment modalities. ( 12365698 )
2002
17
BVAT distance vs. near stereopsis screening of strabismus, strabismic amblyopia and refractive amblyopia; a prospective study of 68 patients. ( 10960226 )
2000
18
Efficacy of treatment modalities in refractive amblyopia. ( 10437342 )
1999
19
Effectiveness of occlusion therapy in ametropic amblyopia. ( 9924395 )
1998
20
Effectiveness of occlusion therapy in ametropic amblyopia: a pilot study. ( 9505818 )
1997
21
Ametropic amblyopia. ( 21314500 )
1993
22
Treatment of refractive amblyopia in adults. ( 3429755 )
1987
23
Amblyopia case reports--bilateral hypermetropic ametropic amblyopia. ( 4045650 )
1985
24
Refractive amblyopia: a preventable vision condition. ( 489867 )
1979
25
Refractive amblyopia: a differential diagnosis. ( 649915 )
1978
26
Refractive amblyopia: its classification, etiology, and epidemiology. ( 874274 )
1977
27
Bilateral ametropic amblyopia resulting from bilateral cornea plana. ( 5028981 )
1972
28
Refractive amblyopia. ( 5129705 )
1971
29
The significance and characteristics of ametropic amblyopia. ( 5721416 )
1968
30
The significance and characteristics of ametropic amblyopia. ( 5729770 )
1968

Variations for Ametropic Amblyopia

Expression for Ametropic Amblyopia

Search GEO for disease gene expression data for Ametropic Amblyopia.

Pathways for Ametropic Amblyopia

GO Terms for Ametropic Amblyopia

Cellular components related to Ametropic Amblyopia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell junction GO:0030054 8.92 CADM1 GABBR1 SDCBP SH3PXD2B

Biological processes related to Ametropic Amblyopia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 9.16 EP300 SDCBP
2 extracellular negative regulation of signal transduction GO:1900116 8.96 MTRNR2L4 MTRNR2L5
3 negative regulation of execution phase of apoptosis GO:1900118 8.62 MTRNR2L4 MTRNR2L5

Molecular functions related to Ametropic Amblyopia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ephrin receptor binding GO:0046875 8.96 CHN1 SDCBP
2 receptor antagonist activity GO:0048019 8.62 MTRNR2L4 MTRNR2L5

Sources for Ametropic Amblyopia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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