Aliases & Classifications for Amnestic Disorder

MalaCards integrated aliases for Amnestic Disorder:

Name: Amnestic Disorder 12 15 72
Amnesia 12 75 55 44 15 17 72
Korsakoff's Psychosis or Syndrome 12
Amnestic Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10914
ICD9CM 35 294.0
MeSH 44 D000647
NCIt 50 C2867
ICD10 33 R41.3
UMLS 72 C0002622 C0002625

Summaries for Amnestic Disorder

Disease Ontology : 12 A cognitive disorder where the memory is disturbed or lost and involves the loss of memories previously established, loss of the ability to create new memories, or loss of the ability to learn new information.

MalaCards based summary : Amnestic Disorder, also known as amnesia, is related to anterograde amnesia and wernicke-korsakoff syndrome, and has symptoms including mental and behavioral signs and symptoms, forgetful and memory loss. An important gene associated with Amnestic Disorder is CHAT (Choline O-Acetyltransferase), and among its related pathways/superpathways are Peptide ligand-binding receptors and Transmission across Chemical Synapses. The drugs Promethazine and Diphenhydramine have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and temporal lobe, and related phenotypes are behavior/neurological and homeostasis/metabolism

Wikipedia : 75 Amnesia is a deficit in memory caused by brain damage or disease, but it can also be caused temporarily... more...

Related Diseases for Amnestic Disorder

Diseases related to Amnestic Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 402)
# Related Disease Score Top Affiliating Genes
1 anterograde amnesia 32.4 HTR1A EIF4G2
2 wernicke-korsakoff syndrome 32.3 CHAT ACHE
3 agnosia 31.4 PDYN OPRM1 OPRK1 HTR7 CNR1
4 dissociative amnesia 30.7 PDYN HTR1A
5 migraine with or without aura 1 30.5 HTR7 HTR3A HTR1A CNR1
6 temporal lobe epilepsy 30.4 TSPO PDYN LGI1 HTR1A BDNF
7 mood disorder 30.1 HTR1A CREB1 BDNF
8 autoimmune encephalitis 30.1 LGI1 CNR1
9 mental depression 30.1 HTR7 HTR1A BDNF
10 major depressive disorder 30.0 HTR3A HTR1A CREB1 BDNF
11 psychotic disorder 30.0 HTR3A HTR1A BDNF
12 dementia 29.9 CHAT BDNF BCHE ACHE
13 toxic encephalopathy 29.9 CREB1 BDNF ACHE
14 vascular dementia 29.8 CHAT BCHE ACHE
15 huntington disease 29.8 CREB1 CNR1 CHAT BDNF
16 focal epilepsy 29.7 TSPO PDYN LGI1
17 pain agnosia 29.7 PDYN OPRM1 OPRK1 HTR7 CNR1
18 anxiety 29.6 TSPO HTR3A HTR1A CNR1 BDNF
19 opiate dependence 29.4 PDYN OPRM1 OPRK1 OPRD1 CREB1
20 withdrawal disorder 28.8 TSPO PDYN OPRM1 HTR7 CNR1
21 parkinson disease, late-onset 28.8 PDYN HTR1A CNR1 CHAT BDNF ACHE
22 schizophrenia 28.4 HTR7 HTR3A HTR1A CNR1 BDNF
23 alcohol dependence 27.7 TSPO PDYN OPRM1 OPRK1 OPRD1 HTR3A
24 hhv-6 encephalitis 11.6
25 traumatic brain injury 11.6
26 aphasia 11.5
27 retrograde amnesia 11.5
28 transient global amnesia 11.2
29 morvan's fibrillary chorea 11.2
30 cerebral beriberi 11.2
31 korsakoff's amnesic syndrome 11.2
32 head injury 10.7
33 encephalitis 10.7
34 brain injury 10.6
35 schizophrenia 5 10.6 HTR3A HTR1A
36 ocular motor apraxia 10.5
37 seizure disorder 10.5
38 visual epilepsy 10.5
39 cerebrovascular disease 10.5
40 phobic disorder 10.4 OPRK1 HTR1A
41 social phobia 10.4 HTR3A HTR1A
42 panic disorder 10.4 TSPO HTR3A HTR1A
43 herpes simplex encephalitis 10.4
44 alzheimer disease 10.4
45 transient cerebral ischemia 10.4
46 limbic encephalitis 10.4
47 epilepsy 10.4
48 opioid abuse 10.3 PDYN OPRM1
49 constipation 10.3 OPRM1 HTR3A CHAT
50 herpes simplex 10.3

Comorbidity relations with Amnestic Disorder via Phenotypic Disease Network (PDN):


Acute Cystitis Alzheimer Disease
Schizophreniform Disorder

Graphical network of the top 20 diseases related to Amnestic Disorder:



Diseases related to Amnestic Disorder

Symptoms & Phenotypes for Amnestic Disorder

UMLS symptoms related to Amnestic Disorder:


mental and behavioral signs and symptoms, forgetful, memory loss

MGI Mouse Phenotypes related to Amnestic Disorder:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.31 ACHE BDNF CHAT CNR1 CREB1 EIF4G2
2 homeostasis/metabolism MP:0005376 10.24 ACHE BCHE BDNF CHAT CNR1 CREB1
3 growth/size/body region MP:0005378 10.14 ACHE BDNF CHAT CNR1 CREB1 EIF4G2
4 mortality/aging MP:0010768 10.07 ACHE BCHE BDNF CHAT CNR1 CREB1
5 integument MP:0010771 9.97 BDNF CNR1 HTR3A HTR7 LGI1 OPRD1
6 nervous system MP:0003631 9.97 ACHE BDNF CHAT CNR1 CREB1 HTR1A
7 no phenotypic analysis MP:0003012 9.5 ACHE BDNF CNR1 HTR1A OPRD1 OPRM1
8 reproductive system MP:0005389 9.32 ACHE BCHE BDNF CHAT CNR1 CREB1

Drugs & Therapeutics for Amnestic Disorder

Drugs for Amnestic Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 214)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Promethazine Approved, Investigational Phase 4 60-87-7 4927
2
Diphenhydramine Approved, Investigational Phase 4 58-73-1, 147-24-0 3100
3
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
4
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
5
Methadone Approved, Illicit Phase 4 76-99-3 4095
6
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
7
Morphine Approved, Investigational Phase 4 57-27-2 5288826
8
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
9
Methohexital Approved Phase 4 151-83-7 9034
10
Alprazolam Approved, Illicit, Investigational Phase 4 28981-97-7 2118
11
Meperidine Approved Phase 4 57-42-1 4058
12
Nicotine Approved Phase 4 54-11-5 942 89594
13
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
14
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
15
Succinylcholine Approved Phase 4 306-40-1 5314
16
Sotalol Approved Phase 4 959-24-0, 3930-20-9 5253
17
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
18
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
19
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
20
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
21
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
22
Remifentanil Approved Phase 4 132875-61-7 60815
23
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
24
Memantine Approved, Investigational Phase 4 19982-08-2 4054
25
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
26
Azaperone Investigational, Vet_approved Phase 4 1649-18-9
27 Antiemetics Phase 4
28 Gastrointestinal Agents Phase 4
29 Antipruritics Phase 4
30 Anti-Allergic Agents Phase 4
31 Histamine H1 Antagonists Phase 4
32 Respiratory System Agents Phase 4
33 Free Radical Scavengers Phase 4
34 Anti-Infective Agents Phase 4
35 N-monoacetylcystine Phase 4
36 Expectorants Phase 4
37 Antiviral Agents Phase 4
38 Antidotes Phase 4
39 cysteine Phase 4
40 Chlorpheniramine, phenylpropanolamine drug combination Phase 4
41 Antitussive Agents Phase 4
42 Cholinergic Agents Phase 4
43 Pharmaceutical Solutions Phase 4
44 Antipsychotic Agents Phase 4
45 Neuromuscular Agents Phase 4
46 Nicotinic Agonists Phase 4
47 Antioxidants Phase 4
48 Protective Agents Phase 4
49 Neuromuscular Depolarizing Agents Phase 4
50 Neuromuscular Blocking Agents Phase 4

Interventional clinical trials:

(show top 50) (show all 159)
# Name Status NCT ID Phase Drugs
1 Phase 4 Study of Balanced Propofol Sedation Versus Propofol Alone Sedation Unknown status NCT01321047 Phase 4 Propofol;BPS
2 Use of Diphenhydramine as an Adjunctive Sedative for Colonoscopy in Patients Chronically on Opioids Unknown status NCT01967433 Phase 4 Diphenhydramine;Placebo
3 Evaluation Whether Higher Retention Rate is in Those of Combined Methadone With N-Acetyl-Cysteine Compared to Those With Methadone Alone During a Six-month Study Unknown status NCT01047956 Phase 4 Methadone; NAC;Methadone
4 Moderate Versus Deep Procedural Sedation With Propofol in the Emergency Department Completed NCT02404610 Phase 4 propofol
5 A One-Year, Multicenter, Randomized, Double-Blind, Placebo-Controlled Evaluation of the Efficacy and Safety of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment (MCI) Completed NCT00293176 Phase 4 Donepezil Hydrochloride;Placebo
6 A Prospective Randomized Double Blinded Control Trial Using Ketamine or Propofol Anesthesia for Electroconvulsive Therapy: Improving Treatment-Resistant Depression Completed NCT01935115 Phase 4 Propofol;Ketamine
7 Randomized Blinded Three Arm Trial of Propofol, 1:1 Combination of Propofol and Ketamine, and 4:1 Combination of Propofol and Ketamine for Procedural Sedation in the Emergency Department Completed NCT01260662 Phase 4 Propofol;1:1 Propofol/Ketamine;4:1 Propofol/Ketamine
8 Use of Nitrous Oxide for Analgesia During Colonoscopy - A Randomised Trial Completed NCT00318825 Phase 4 Nitrous oxide
9 A Randomised Controlled Trial of Standard Bilateral Electroconvulsive Therapy Versus High-dose Unilateral Electroconvulsive Therapy for Severe Depression Completed NCT01907217 Phase 4 Methohexitone;Suxamethonium
10 Comparing Therapeutic Efficacy and Cognitive Side Effects of Electroconvulsive Therapy (ECT) Using Ketamine Versus Methohexital Anesthesia Completed NCT01881763 Phase 4 Ketamine;Methohexital
11 Does the Administration of Preop Midazolam Assist in Maintaining Blood Glucose Norms in Non-diabetic Patient During the Perioperative Period Completed NCT01641653 Phase 4 Midazolam
12 Intranasal Ketamine Versus Intranasal Midazolam Plus Fentanyl in Treating Pain Associated With Incision and Drainage of Abscesses in the Pediatric Emergency Department: A Randomized Controlled Trial Completed NCT02635282 Phase 4 intranasal ketamine;intranasal fentanyl;intranasal midazolam
13 Premedication With Melatonin and Alprazolam Combination Versus Alprazolam or Melatonin Alone: a Randomized, Double Blind Placebo Controlled Study Completed NCT01486615 Phase 4 meloset (melatonin);stresnil ( melatonin and alprazolam);(alprax) alprazolam;placebo
14 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy of Propofol or Midazolam Versus Placebo for Preoperative Medication in Patients Undergoing Elective Orthopedic Surgery Completed NCT01976845 Phase 4 Midazolam;Propofol;Saline
15 Low Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency Department: A Prospective, Randomized, Double-Blind Study Completed NCT01835262 Phase 4 Morphine;Ketamine
16 Bronchoscopy Under Titrated Sedation With Propofol or Midazolam: a Randomized Trial. Completed NCT00839371 Phase 4 Propofol;Midazolam
17 Study of Comparison of the Effectiveness of Three Diagrams for Sedation in Spinal Anesthesia Completed NCT02136641 Phase 4 Midazolam;Midazolam+Fentanyl Combination;Midazolam+Ketamine Combination
18 Midazolam With Meperidine and Dexmedetomidine vs Midazolam With Meperidine for Sedation During ERCP Completed NCT01404689 Phase 4 Dexmedetomidine
19 Intranasal Nicotine for Postoperative Pain Treatment: A Comparison of Its Effects in the Context of Isoflurane-induced Anesthesia Versus Propofol Anesthesia Completed NCT00232817 Phase 4 Nicotine (drug)
20 EFFICACY OF KETAMINE-PROPOFOL COMBINATION FOR SHORT SURGICAL PROCEDURES Completed NCT01651988 Phase 4 Ketamina-Propofol Combination
21 Efficacy of Lidocaine as Local Anesthetics in Children Under Procedural Sedation and Analgesia Using Ketamine Recruiting NCT02205502 Phase 4 Lidocaine;Normal saline
22 Pharmacological Preconditioning Properties of Volatile Anesthetics Recruiting NCT00364637 Phase 4 Sevoflurane (Volatile Anesthetic);Total intravenous anesthesia
23 A Prospective Randomized Controlled Trial of Electroconvulsive Therapy With Ketamine Anesthesia (Standard Therapy) and High Intensity Ketamine With Electroconvulsive Therapy Rescue for Treatment-Resistant Depression - EAST HIKER Trial Recruiting NCT03272698 Phase 4 Ketamine
24 A Pilot and Feasibility Study to Determine if a Common Atrial Fibrillation Risk Locus Modulates Differential Response to Antiarrhythmic Drugs Recruiting NCT02347111 Phase 4 Flecainide;Sotalol
25 Neuroimaging the Effects of Intravenous Anesthetic on Amygdala Dependent Memory Processes Active, not recruiting NCT00504894 Phase 4 Placebo;Propofol
26 Remifentanil Versus Propofol With Target Controlled Infusion Effect Site for the Sedation of Patients During Gastrointestinal Endoscopic Procedures: Randomized Controlled Trial Terminated NCT01746641 Phase 4 Remifentanil;Propofol
27 Comparison of the Effectiveness of Sedation With i.v. Dexmedetomidine in Combination With Midazolam Alone or Midazolam and Low Dose Ketamine for Extraction of Third Molars. Terminated NCT01017237 Phase 4 Dexmedetomidine;Midazolam;Ketamine
28 Comparison of Sub-dissociative Dose Intranasal Ketamine to Intranasal Fentanyl for Treatment of Moderate to Severe Pain in Pediatric Patients Presenting to the Emergency Department: a Prospective, Randomized, Double-blind Study Terminated NCT02388321 Phase 4 Ketamine;Fentanyl
29 Double-blind Cross-over Study of the Effect of Namenda on Short Term Memory and Attention in Patients With Mild to Moderate Traumatic Brain Injury, Protocol NAM-MD-44 Terminated NCT00462228 Phase 4 Memantine;Placebo
30 Interventional Study of Dexmedetomidine for Sedating Anticipated Difficult Airway Patients Undergoing Awake Fiberoptic Nasal Intubation Unknown status NCT00815893 Phase 2, Phase 3 dexmedetomidine;Normal Saline 0.9%;propofol 1%
31 A Prospective Multicenter Double Blind Randomized Controlled Trial to Explore the Tolerability, Safety and Efficacy of the H1-Coil Deep Transcranial Magnetic Stimulation (TMS) in Subjects With Schizophrenia Experiencing Auditory Hallucinations Unknown status NCT00564096 Phase 2, Phase 3
32 Magnetic Seizure Therapy (MST) for the Treatment of Severe Mood Disorder Completed NCT00488748 Phase 3
33 Comparison of Ketamine Versus Co-Administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department Completed NCT01387139 Phase 3 Ketamine;Ketamine Co-administered with Propofol
34 Focal Electrical Administered Seizure Therapy (FEAST) for Major Depression Completed NCT01589315 Phase 2, Phase 3
35 Combination Pharmacotherapy With Chantix & Bupropion for Smoking Cessation (ChanBan) Completed NCT00587769 Phase 3 Bupropion SR & Varenicline
36 Evaluation of an Active Strategy to Implement the Canadian CT Head Rule: Phase III Completed NCT00993252 Phase 3
37 A Study to Assess the Analgesia and Sedation Using Intranasal Dexmedetomidine in Third Molar Surgery Under Local Anaesthesia Completed NCT01132794 Phase 3 Intranasal dexmedetomidine;Placebo
38 Treatment Strategy to Prevent Mood Disorders Following Traumatic Brain Injury Completed NCT00704379 Phase 2, Phase 3 Placebo;Sertraline
39 Success of Sedation During Bronchoscopy: Comparison of the Effects of Dexmedetomidine, Alfentanil and Local Anesthesia Completed NCT01805726 Phase 3 xylocain;Alfentanil;Dexmedetomidine
40 A Randomized Double-blind Trial to Evaluate Ketamine-propofol Combination vs. Propofol Alone for Procedural Sedation and Analgesia in the Emergency Department. Completed NCT01211158 Phase 3 Ketofol;Propofol alone
41 An Open-Label, Randomised, Active Controlled, Multi-Centre Phase 3 Study to Evaluate the Safety and Efficacy of Danaparoid vs Argatroban in Treatment of Subjects With Acute HIT (HITSOVA Study) Recruiting NCT03809481 Phase 3 Danaparoid Sodium;Argatroban
42 A Randomized Controlled Non-inferiority Trial Comparing Ketamine With ECT in Patients With Major Depressive Disorder Active, not recruiting NCT02659085 Phase 2, Phase 3 Ketamine IV Infusion
43 Focal Electrically-Administered Seizure Therapy (FEAST): Studies at Two Enrolling Sites to Further Test and Refine the Treatment Active, not recruiting NCT02535572 Phase 2, Phase 3
44 PCSK9 Inhibitor: a New Tool to Fight Septic Shock Not yet recruiting NCT03634293 Phase 2, Phase 3 Alirocumab Injectable Product;Saline Solution
45 A Phase III, Randomized, Open-label Study to Assess the Safety and Efficacy of AQUAVAN® Injection Versus Midazolam HCl for Sedation in Patients Undergoing Minor Surgical Procedures Terminated NCT00209560 Phase 3 fospropofol disodium
46 Sodium Butyrate As A Treatment For Improving Cognitive Function In Schizophrenia Withdrawn NCT02654405 Phase 2, Phase 3
47 Phase II Study of Rosuvastatin´s Effect on Amnesia and Orientation Through Galveston Outcome Amnesia Test in Humans With Moderate Head Injury Completed NCT00329758 Phase 2 rosuvastatin;Placebo
48 Premedication With Different Nebulized Ketamine,Dexmedetomidine Versus Midazolam in Oncologic Preschool Children Completed NCT02935959 Phase 1, Phase 2 nebulized ketamine;nebulized Dexmedetomidine;nebulized midazolam
49 Effect of Rosuvastatin on Immunological Markers After Traumatic Brain Injury: Clinical Randomized Double Blind Study Phase 2 Completed NCT00990028 Phase 1, Phase 2 Rosuvastatin;Placebo
50 The Minimum Effective Dose of Remifentanil When Co-administered With Propofol for Lumbar Puncture in Children: A Dose-finding Study Completed NCT00213239 Phase 1, Phase 2 Remifentanil;Remifentanil

Search NIH Clinical Center for Amnestic Disorder

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Methotrimeprazine

Cochrane evidence based reviews: amnesia

Genetic Tests for Amnestic Disorder

Anatomical Context for Amnestic Disorder

MalaCards organs/tissues related to Amnestic Disorder:

41
Brain, Testes, Temporal Lobe, Cortex, Amygdala, Thalamus, Prefrontal Cortex

Publications for Amnestic Disorder

Articles related to Amnestic Disorder:

(show top 50) (show all 9846)
# Title Authors PMID Year
1
Cryptotanshinone, an acetylcholinesterase inhibitor from Salvia miltiorrhiza, ameliorates scopolamine-induced amnesia in Morris water maze task. 9 38
19774505 2010
2
Memory formation, amnesia, improved memory and reversed amnesia: 5-HT role. 9 38
18221797 2008
3
Antibodies to voltage-gated potassium and calcium channels in epilepsy. 9 38
16870397 2006
4
Study of PMS777, a new type of acetylcholinesterase inhibitor, in human HepG2 cells. Comparison with tacrine and galanthamine on oxidative stress and mitochondrial impairment. 9 38
16472967 2006
5
Unclosed beta-propellers display stable structures: implications for substrate access to the active site of prolyl oligopeptidase. 9 38
15713471 2005
6
The prolyl oligopeptidase family. 9 38
11915948 2002
7
Inhibition of passive-avoidance memory formation in the day-old chick by the opioid cytochrophin-4. 9 38
10940321 2000
8
Identification of the opioid receptors involved in passive-avoidance learning in the day-old chick during the second wave of neuronal activity. 9 38
10802030 2000
9
Improving effects of huperzine A on spatial working memory in aged monkeys and young adult monkeys with experimental cognitive impairment. 9 38
9918593 1999
10
Physiological, pathophysiological and therapeutic roles of 5-HT systems in learning and memory. 9 38
9886142 1998
11
[Biochemical studies on functional proteins in the brain nervous system. Neurobiochemical studies on nerve growth factor]. 9 38
8709005 1996
12
[The interaction of dopamine and opioid receptors in the re-establishing of an amnesic and forgotten memory trace by quinpirole]. 9 38
7773079 1995
13
Effects of nefiracetam, DM-9384 on amnesia and decrease in choline acetyltransferase activity induced by cycloheximide. 9 38
1463591 1992
14
[Experimental study of the effects of amiridin and tacrine on learning and memory]. 9 38
1893185 1991
15
Involvement of the cholinergic neuronal system and benzodiazepine receptors in alcohol-induced amnesia. 9 38
1651866 1991
16
The role of GABAA and GABAB receptors in the development of amnesia. 9 38
2177529 1990
17
Cholinergic receptor antagonists impair formation of intermediate-term memory in the chick. 9 38
2378607 1990
18
Long-term autobiographical memory across middle childhood: patterns, predictors, and implications for conceptualizations of childhood amnesia. 38
31331241 2019
19
Ghrelin modulates morphine-nicotine interaction in avoidance memory: Involvement of CA1 nicotinic receptors. 38
31260652 2019
20
Errorless (re)learning of everyday activities in patients with Korsakoff's syndrome: A feasibility study. 38
28967298 2019
21
Matured hop bitter acids improve spatial working and object recognition memory via nicotinic acetylcholine receptors. 38
31069423 2019
22
Mild traumatic brain injury characteristics do not negatively influence cognitive processing therapy attendance or outcomes. 38
31174014 2019
23
Dissociative identity as a continuum from healthy mind to psychiatric disorders: Epistemological and neurophenomenological implications approached through hypnosis. 38
31383343 2019
24
Gadolinium leakage in ocular structures: A novel MRI finding in transient global amnesia. 38
31330456 2019
25
Retrosplenial cortex damage produces retrograde and anterograde context amnesia using strong fear conditioning procedures. 38
31039379 2019
26
Hippocampal network abnormalities explain amnesia after VGKCC-Ab related autoimmune limbic encephalitis. 38
31072956 2019
27
Effects of amnesia on processing in the hippocampus and default mode network during a naturalistic memory task: A case study. 38
31260681 2019
28
Development of pyrazole and spiropyrazoline analogs as multifunctional agents for treatment of Alzheimer's disease. 38
31271946 2019
29
Transient hippocampal CA1 lesions in humans impair pattern separation performance. 38
30706576 2019
30
Smell your memories: Positive effect of odor exposure on recent and remote autobiographical memories in Alzheimer's disease. 38
30890017 2019
31
Indigenous traumatic brain injury research: responding to recruitment challenges in the hospital environment. 38
31390984 2019
32
Parallel pathways of seizure generalization. 38
31237945 2019
33
Dopaminergic D1 receptor signalling is necessary, but not sufficient for cued fear memory destabilisation. 38
31392356 2019
34
Insights into the mechanisms of epilepsy from structural biology of LGI1-ADAM22. 38
31432233 2019
35
Anesthetic Management During Electroconvulsive Therapy in Children: A Systematic Review of the Available Literature. 38
31425262 2019
36
A human memory circuit derived from brain lesions causing amnesia. 38
31375668 2019
37
Mammillothalamic Disconnection Alters Hippocampocortical Oscillatory Activity and Microstructure: Implications for Diencephalic Amnesia. 38
31235646 2019
38
Does attribute amnesia occur with the presentation of complex, meaningful stimuli? The answer is, "it depends". 38
30924060 2019
39
Effectiveness of Yi-Zhi-An-Shen granules on cognition and sleep quality in older adults with amnestic mild cognitive impairment: protocol for a randomized, double-blind, placebo-controlled trial. 38
31429790 2019
40
Proteins or RNA synthesis inhibitors suppressed induction of amnesia developing under impairment of memory reconsolidation by serotonin receptors antagonist. 38
31400436 2019
41
The Long-Term Risk of Dementia after Transient Global Amnesia: A Population-Based Cohort Study in Taiwan. 38
31422402 2019
42
Caffeine improves sperm quality, modulates steroidogenic enzyme activities, restore testosterone levels and prevent oxidative damage in testicular and epididymal tissues of scopolamine-induced rat model of amnesia. 38
31385305 2019
43
Hippocampal Damage Causes Retrograde Amnesia and Slower Acquisition of a Cue-Place Discrimination in a Concurrent Cue-Place Water Task in Rats. 38
31195054 2019
44
Cross state-dependent memory retrieval between morphine and norharmane in the mouse dorsal hippocampus. 38
31400494 2019
45
Cortico-hippocampal memory enhancing activity of hesperetin on scopolamine-induced amnesia in mice: role of antioxidant defense system, cholinergic neurotransmission and expression of BDNF. 38
30949953 2019
46
SREDA: A Rare but Confusing Benign EEG Variant. 38
31393275 2019
47
NRGN, S100B and GFAP levels are significantly increased in patients with structural lesions resulting from mild traumatic brain injuries. 38
31234132 2019
48
Detecting clinical and simulated dissociative identity disorder with the Test of Memory Malingering. 38
30211601 2019
49
μ-Opioid receptor in the CA1 involves in tramadol and morphine cross state-dependent memory. 38
31051223 2019
50
Identification of a Novel Peptide from β-Casein That Enhances Spatial and Object Recognition Memory in Mice. 38
31241932 2019

Variations for Amnestic Disorder

Expression for Amnestic Disorder

Search GEO for disease gene expression data for Amnestic Disorder.

Pathways for Amnestic Disorder

Pathways related to Amnestic Disorder according to GeneCards Suite gene sharing:

(show all 18)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.89 TSPO PDYN OPRM1 OPRK1 OPRD1 HTR7
2
Show member pathways
12.79 GABRR3 CREB1 CHAT BCHE ACHE
3 12.33 OPRM1 HTR1A CREB1 CNR1
4 11.89 CREB1 CNR1 BDNF
5 11.8 TSPO HTR1A CNR1
6
Show member pathways
11.72 PDYN CREB1 BDNF
7 11.69 HTR7 HTR3A HTR1A
8 11.29 OPRK1 CREB1 BDNF
9 11.23 HTR3A HTR1A CREB1 CHAT BDNF
10 11.01 CREB1 BDNF
11
Show member pathways
10.98 BCHE ACHE
12
Show member pathways
10.89 CHAT ACHE
13 10.88 CHAT BCHE ACHE
14 10.79 HTR7 CREB1
15 10.78 HTR7 HTR3A HTR1A
16 10.58 CREB1 BDNF
17 10.48 CHAT ACHE
18 10.21 CHAT ACHE

GO Terms for Amnestic Disorder

Cellular components related to Amnestic Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.86 OPRM1 OPRK1 OPRD1 HTR7 HTR3A HTR1A
2 synapse GO:0045202 9.83 OPRK1 LGI1 HTR3A GABRR3 ACHE
3 dendrite GO:0030425 9.63 PDYN OPRM1 OPRK1 HTR7 HTR1A BDNF
4 axon terminus GO:0043679 9.58 PDYN OPRK1 OPRD1
5 integral component of postsynaptic membrane GO:0099055 9.54 OPRM1 OPRK1 HTR3A
6 synaptic cleft GO:0043083 9.46 LGI1 ACHE
7 axon GO:0030424 9.43 OPRM1 HTR3A EIF4G2 CREB1 CNR1 BDNF
8 spine apparatus GO:0097444 9.32 OPRM1 OPRD1
9 integral component of presynaptic membrane GO:0099056 9.02 OPRM1 OPRK1 OPRD1 HTR3A CNR1
10 membrane GO:0016020 10.26 TSPO OPRM1 OPRK1 OPRD1 HTR7 HTR3A

Biological processes related to Amnestic Disorder according to GeneCards Suite gene sharing:

(show all 25)
# Name GO ID Score Top Affiliating Genes
1 memory GO:0007613 9.76 CREB1 CNR1 BDNF
2 response to ethanol GO:0045471 9.76 OPRM1 OPRK1 HTR3A CNR1
3 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0007193 9.73 OPRM1 OPRK1 OPRD1
4 cellular response to growth factor stimulus GO:0071363 9.72 OPRD1 HTR3A CREB1
5 phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 9.71 OPRM1 OPRK1 OPRD1
6 sensory perception of pain GO:0019233 9.7 OPRM1 OPRK1 CNR1
7 regulation of sensory perception of pain GO:0051930 9.67 OPRM1 OPRK1 OPRD1
8 response to morphine GO:0043278 9.65 OPRM1 OPRK1 CNR1
9 cellular response to zinc ion GO:0071294 9.62 TSPO CREB1
10 cell proliferation GO:0008283 9.62 HTR1A ACHE
11 neuropeptide signaling pathway GO:0007218 9.62 PDYN OPRM1 OPRK1 OPRD1
12 vasoconstriction GO:0042310 9.61 HTR7 HTR1A
13 estrous cycle GO:0044849 9.61 OPRM1 OPRK1
14 neurotransmitter biosynthetic process GO:0042136 9.6 CHAT ACHE
15 sensory perception GO:0007600 9.59 OPRM1 OPRK1
16 serotonin receptor signaling pathway GO:0007210 9.58 HTR3A HTR1A
17 behavior GO:0007610 9.57 OPRK1 HTR1A
18 eating behavior GO:0042755 9.54 OPRM1 OPRK1 OPRD1
19 response to cocaine GO:0042220 9.46 OPRM1 OPRK1 HTR3A CNR1
20 adenylate cyclase-inhibiting opioid receptor signaling pathway GO:0031635 9.43 OPRM1 OPRK1
21 opioid receptor signaling pathway GO:0038003 9.43 OPRM1 OPRK1 OPRD1
22 chemical synaptic transmission GO:0007268 9.43 PDYN OPRK1 HTR7 HTR3A HTR1A GABRR3
23 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 9.02 OPRM1 OPRD1 HTR7 HTR1A CNR1
24 signal transduction GO:0007165 10.06 OPRM1 OPRK1 OPRD1 HTR7 HTR3A HTR1A
25 G protein-coupled receptor signaling pathway GO:0007186 10.05 PDYN OPRM1 OPRK1 OPRD1 HTR7 HTR1A

Molecular functions related to Amnestic Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor activity GO:0004930 9.85 OPRM1 OPRK1 OPRD1 HTR7 HTR1A CNR1
2 serotonin binding GO:0051378 9.4 HTR3A HTR1A
3 receptor serine/threonine kinase binding GO:0033612 9.32 OPRK1 OPRD1
4 cholinesterase activity GO:0004104 9.26 BCHE ACHE
5 acetylcholinesterase activity GO:0003990 9.16 BCHE ACHE
6 neuropeptide binding GO:0042923 9.13 OPRM1 OPRK1 OPRD1
7 opioid receptor activity GO:0004985 8.8 OPRM1 OPRK1 OPRD1

Sources for Amnestic Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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