Aliases & Classifications for Amnestic Disorder

MalaCards integrated aliases for Amnestic Disorder:

Name: Amnestic Disorder 12 15 71
Amnesia 12 74 54 43 15 17 71
Korsakoff's Psychosis or Syndrome 12
Amnestic Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10914
ICD9CM 34 294.0
MeSH 43 D000647
NCIt 49 C2867
SNOMED-CT 67 3298001 48167000
ICD10 32 R41.3
UMLS 71 C0002622 C0002625

Summaries for Amnestic Disorder

Disease Ontology : 12 A cognitive disorder where the memory is disturbed or lost and involves the loss of memories previously established, loss of the ability to create new memories, or loss of the ability to learn new information.

MalaCards based summary : Amnestic Disorder, also known as amnesia, is related to aphasia and agnosia, and has symptoms including mental and behavioral signs and symptoms, forgetful and memory loss. An important gene associated with Amnestic Disorder is PREP (Prolyl Endopeptidase), and among its related pathways/superpathways are Peptide ligand-binding receptors and Transmission across Chemical Synapses. The drugs Acetylcysteine and Methadone have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and temporal lobe, and related phenotypes are behavior/neurological and homeostasis/metabolism

Wikipedia : 74 Amnesia is a deficit in memory caused by brain damage or disease, but it can also be caused temporarily... more...

Related Diseases for Amnestic Disorder

Diseases related to Amnestic Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 428)
# Related Disease Score Top Affiliating Genes
1 aphasia 32.9 LGI1 BDNF APP
2 agnosia 32.7 PDYN OPRM1 OPRK1 OPRD1 HTR3A HTR1A
3 wernicke-korsakoff syndrome 32.6 CHAT BDNF ACHE
4 transient global amnesia 32.4 LGI1 BDNF
5 retrograde amnesia 32.2 PDYN IMPACT HTR1A GRIN2B CREB1 BDNF
6 anterograde amnesia 31.7 LGI1 IMPACT HTR1A GRIN2B GABRR3 BDNF
7 limbic encephalitis 31.2 LGI1 GRIN2B GAD1
8 pain agnosia 31.1 PDYN OPRM1 OPRK1 OPRD1 HTR3A HTR1A
9 post-traumatic stress disorder 31.1 PREP HTR1A BDNF
10 personality disorder 30.9 HTR3A HTR1A BDNF
11 status epilepticus 30.8 TSPO LGI1 GRIN2B BDNF ACHE
12 temporal lobe epilepsy 30.7 TSPO PDYN OPRM1 LGI1 HTR1A GRIN2B
13 borderline personality disorder 30.6 HTR3A HTR1A BDNF
14 dementia 30.6 TSPO HTR1A CHAT BDNF BCHE APP
15 migraine with or without aura 1 30.5 PDYN OPRM1 OPRK1 OPRD1 IMPACT HTR3A
16 dissociative disorder 30.5 GRIN2B BDNF
17 mental depression 30.5 HTR3A HTR1A GRIN2B CREB1 BDNF
18 mood disorder 30.3 HTR3A HTR1A GAD1 CREB1 BDNF
19 epilepsy 30.3 TSPO PDYN LGI1 GRIN2B GAD1 CREB1
20 somatoform disorder 30.3 OPRM1 HTR3A BDNF
21 huntington disease 30.3 TSPO GRIN2B CREB1 CHAT BDNF APP
22 opiate dependence 30.2 PDYN OPRM1 OPRK1 OPRD1 CREB1
23 stiff-person syndrome 30.2 LGI1 GAD1 GABRR3
24 substance abuse 30.2 PDYN OPRM1 OPRK1 OPRD1 HTR1A BDNF
25 vascular dementia 30.1 HTR1A GRIN2B CHAT BCHE APP ACHE
26 alcohol use disorder 30.1 OPRM1 HTR3A HTR1A GRIN2B CREB1 BDNF
27 major depressive disorder 30.1 OPRM1 HTR3A HTR1A GRIN2B GAD1 CREB1
28 alzheimer disease 30.1 TSPO PREP HTR1A GRIN2B CREB1 CHAT
29 peripheral nervous system disease 30.0 OPRM1 BDNF APP ACHE
30 withdrawal disorder 30.0 TSPO PDYN OPRM1 OPRK1 OPRD1 HTR1A
31 drug dependence 29.9 PDYN OPRM1 OPRK1 OPRD1 HTR3A BDNF
32 speech and communication disorders 29.8 OPRM1 LGI1 GRIN2B BDNF BCHE APP
33 autism 29.7 TSPO OPRM1 HTR3A HTR1A GRIN2B GAD1
34 psychotic disorder 29.7 PDYN OPRM1 HTR3A HTR1A GRIN2B GAD1
35 autism spectrum disorder 29.7 OPRM1 OPRK1 OPRD1 GRIN2B GAD1 BDNF
36 focal epilepsy 29.6 TSPO PDYN LGI1 GRIN2B GAD1 GABRR3
37 neuroblastoma 29.6 OPRM1 LGI1 CREB1 CHAT BDNF APP
38 toxic encephalopathy 29.5 GRIN2B CREB1 CHAT BDNF BCHE APP
39 bipolar disorder 29.3 TSPO PREP PDYN HTR3A HTR1A GRIN2B
40 anxiety 29.2 TSPO PDYN OPRM1 OPRK1 HTR3A HTR1A
41 alcohol dependence 29.2 TSPO PDYN OPRM1 OPRK1 OPRD1 HTR3A
42 schizophrenia 28.8 TSPO PDYN OPRM1 HTR3A HTR1A GRIN2B
43 parkinson disease, late-onset 28.8 TSPO PDYN HTR3A HTR1A GRIN2B GAD1
44 hhv-6 encephalitis 11.6
45 traumatic brain injury 11.6
46 multiple personality disorder 11.5
47 morvan's fibrillary chorea 11.2
48 korsakoff's amnesic syndrome 11.2
49 head injury 10.7
50 encephalitis 10.7

Comorbidity relations with Amnestic Disorder via Phenotypic Disease Network (PDN):


Acute Cystitis Alzheimer Disease
Schizophreniform Disorder

Graphical network of the top 20 diseases related to Amnestic Disorder:



Diseases related to Amnestic Disorder

Symptoms & Phenotypes for Amnestic Disorder

UMLS symptoms related to Amnestic Disorder:


mental and behavioral signs and symptoms, forgetful, memory loss

MGI Mouse Phenotypes related to Amnestic Disorder:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.31 ACHE APP BDNF CHAT CREB1 GAD1
2 homeostasis/metabolism MP:0005376 10.22 ACHE APP BCHE BDNF CHAT CREB1
3 growth/size/body region MP:0005378 10.18 ACHE APP BDNF CHAT CREB1 GAD1
4 mortality/aging MP:0010768 10.1 ACHE APP BCHE BDNF CHAT CREB1
5 nervous system MP:0003631 10.03 ACHE APP BDNF CHAT CREB1 GAD1
6 no phenotypic analysis MP:0003012 9.65 ACHE APP BDNF GAD1 GRIN2B HTR1A
7 reproductive system MP:0005389 9.32 ACHE APP BCHE BDNF CHAT CREB1

Drugs & Therapeutics for Amnestic Disorder

Drugs for Amnestic Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 195)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
2
Methadone Approved Phase 4 76-99-3 4095
3
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
4
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
5
Morphine Approved, Investigational Phase 4 57-27-2 5288826
6
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
7
Promethazine Approved, Investigational Phase 4 60-87-7 4927
8
Diphenhydramine Approved, Investigational Phase 4 58-73-1, 147-24-0 3100
9
Methohexital Approved Phase 4 151-83-7 9034
10
Alprazolam Approved, Illicit, Investigational Phase 4 28981-97-7 2118
11
Nicotine Approved Phase 4 54-11-5 942 89594
12
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
13
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
14
Succinylcholine Approved Phase 4 306-40-1 5314
15
Histamine Approved, Investigational Phase 4 51-45-6 774
16
Meperidine Approved Phase 4 57-42-1 4058
17
Hydroxyzine Approved Phase 4 68-88-2 3658
18
Sotalol Approved Phase 4 3930-20-9, 959-24-0 5253
19
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
20
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
21
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
22
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
23
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 5311068 68602
24
Remifentanil Approved Phase 4 132875-61-7 60815
25
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
26
Memantine Approved, Investigational Phase 4 19982-08-2 4054
27
Cysteine Approved, Nutraceutical Phase 4 52-90-4 5862
28
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
29
Azaperone Investigational, Vet_approved Phase 4 1649-18-9
30 N-monoacetylcystine Phase 4
31 Antitussive Agents Phase 4
32 Chlorpheniramine, phenylpropanolamine drug combination Phase 4
33 Cholinergic Agents Phase 4
34 Pharmaceutical Solutions Phase 4
35 Gastrointestinal Agents Phase 4
36 Antiemetics Phase 4
37 Antipsychotic Agents Phase 4
38 Anti-Allergic Agents Phase 4
39 Nicotinic Agonists Phase 4
40 Antioxidants Phase 4
41 Neuromuscular Blocking Agents Phase 4
42 Dopamine Antagonists Phase 4
43 Protective Agents Phase 4
44 Central Nervous System Stimulants Phase 4
45 Anesthetics, Inhalation Phase 4
46 Dermatologic Agents Phase 4
47 Histamine Antagonists Phase 4
48 Histamine H1 Antagonists Phase 4
49
Histamine Phosphate Phase 4 51-74-1 65513
50 Sodium Channel Blockers Phase 4

Interventional clinical trials:

(show top 50) (show all 171)
# Name Status NCT ID Phase Drugs
1 Efficacy of Lidocaine as Local Anesthetics in Children Under Procedural Sedation and Analgesia Using Ketamine Unknown status NCT02205502 Phase 4 Lidocaine;Normal saline
2 Phase 4 Study of Balanced Propofol Sedation Versus Propofol Alone Sedation Unknown status NCT01321047 Phase 4 Propofol;BPS
3 Evaluation Whether Higher Retention Rate is in Those of Combined Methadone With N-Acetyl-Cysteine Compared to Those With Methadone Alone During a Six-month Study Unknown status NCT01047956 Phase 4 Methadone; NAC;Methadone
4 Moderate Versus Deep Procedural Sedation With Propofol in the Emergency Department Completed NCT02404610 Phase 4 propofol
5 A One-Year, Multicenter, Randomized, Double-Blind, Placebo-Controlled Evaluation of the Efficacy and Safety of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment (MCI) Completed NCT00293176 Phase 4 Donepezil Hydrochloride;Placebo
6 A Prospective Randomized Double Blinded Control Trial Using Ketamine or Propofol Anesthesia for Electroconvulsive Therapy: Improving Treatment-Resistant Depression Completed NCT01935115 Phase 4 Propofol;Ketamine
7 Randomized Blinded Three Arm Trial of Propofol, 1:1 Combination of Propofol and Ketamine, and 4:1 Combination of Propofol and Ketamine for Procedural Sedation in the Emergency Department Completed NCT01260662 Phase 4 Propofol;1:1 Propofol/Ketamine;4:1 Propofol/Ketamine
8 Use of Nitrous Oxide for Analgesia During Colonoscopy - A Randomised Trial Completed NCT00318825 Phase 4 Nitrous oxide
9 Use of Diphenhydramine as an Adjunctive Sedative for Colonoscopy in Patients Chronically on Opioids Completed NCT01967433 Phase 4 Diphenhydramine;Placebo
10 Intranasal Ketamine Versus Intranasal Midazolam Plus Fentanyl in Treating Pain Associated With Incision and Drainage of Abscesses in the Pediatric Emergency Department: A Randomized Controlled Trial Completed NCT02635282 Phase 4 intranasal ketamine;intranasal fentanyl;intranasal midazolam
11 A Randomised Controlled Trial of Standard Bilateral Electroconvulsive Therapy Versus High-dose Unilateral Electroconvulsive Therapy for Severe Depression Completed NCT01907217 Phase 4 Methohexitone;Suxamethonium
12 Comparing Therapeutic Efficacy and Cognitive Side Effects of Electroconvulsive Therapy (ECT) Using Ketamine Versus Methohexital Anesthesia Completed NCT01881763 Phase 4 Ketamine;Methohexital
13 Does the Administration of Preop Midazolam Assist in Maintaining Blood Glucose Norms in Non-diabetic Patient During the Perioperative Period Completed NCT01641653 Phase 4 Midazolam
14 Premedication With Melatonin and Alprazolam Combination Versus Alprazolam or Melatonin Alone: a Randomized, Double Blind Placebo Controlled Study Completed NCT01486615 Phase 4 meloset (melatonin);stresnil ( melatonin and alprazolam);(alprax) alprazolam;placebo
15 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy of Propofol or Midazolam Versus Placebo for Preoperative Medication in Patients Undergoing Elective Orthopedic Surgery Completed NCT01976845 Phase 4 Midazolam;Propofol;Saline
16 Bronchoscopy Under Titrated Sedation With Propofol or Midazolam: a Randomized Trial. Completed NCT00839371 Phase 4 Propofol;Midazolam
17 Low Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency Department: A Prospective, Randomized, Double-Blind Study Completed NCT01835262 Phase 4 Morphine;Ketamine
18 Study of Comparison of the Effectiveness of Three Diagrams for Sedation in Spinal Anesthesia Completed NCT02136641 Phase 4 Midazolam;Midazolam+Fentanyl Combination;Midazolam+Ketamine Combination
19 Intranasal Nicotine for Postoperative Pain Treatment: A Comparison of Its Effects in the Context of Isoflurane-induced Anesthesia Versus Propofol Anesthesia Completed NCT00232817 Phase 4 Nicotine (drug)
20 Midazolam With Meperidine and Dexmedetomidine vs Midazolam With Meperidine for Sedation During ERCP Completed NCT01404689 Phase 4 Dexmedetomidine
21 EFFICACY OF KETAMINE-PROPOFOL COMBINATION FOR SHORT SURGICAL PROCEDURES Completed NCT01651988 Phase 4 Ketamina-Propofol Combination
22 Pharmacological Preconditioning Properties of Volatile Anesthetics Recruiting NCT00364637 Phase 4 Sevoflurane (Volatile Anesthetic);Total intravenous anesthesia
23 A Prospective Randomized Controlled Trial of Electroconvulsive Therapy With Ketamine Anesthesia (Standard Therapy) and High Intensity Ketamine With Electroconvulsive Therapy Rescue for Treatment-Resistant Depression - EAST HIKER Trial Recruiting NCT03272698 Phase 4 Ketamine
24 Effects of Anesthesia Drugs on Neuronal Activity in the Basal Ganglia and Thalamus During Deep Brain Stimulation Electrode Implantation Surgery Recruiting NCT03283150 Phase 4 Remifentanil;Propofol;Dexmedetomidine
25 Neuroimaging the Effects of Intravenous Anesthetic on Amygdala Dependent Memory Processes Active, not recruiting NCT00504894 Phase 4 Placebo;Propofol
26 Comparing Pediatric Oral Sedation Outcomes Using Midazolam and Hydroxyzine With and Without Meperidine Active, not recruiting NCT04068948 Phase 4 Meperidine;Hydroxyzine;Midazolam
27 A Prospective, Multi-Center, Randomized, Open Label Trial to Determine if a Common Atrial Fibrillation Risk Locus Modulates Differential Response to Antiarrhythmic Drugs Not yet recruiting NCT02347111 Phase 4 Flecainide;Sotalol
28 Remifentanil Versus Propofol With Target Controlled Infusion Effect Site for the Sedation of Patients During Gastrointestinal Endoscopic Procedures: Randomized Controlled Trial Terminated NCT01746641 Phase 4 Remifentanil;Propofol
29 Comparison of the Effectiveness of Sedation With i.v. Dexmedetomidine in Combination With Midazolam Alone or Midazolam and Low Dose Ketamine for Extraction of Third Molars. Terminated NCT01017237 Phase 4 Dexmedetomidine;Midazolam;Ketamine
30 Comparison of Sub-dissociative Dose Intranasal Ketamine to Intranasal Fentanyl for Treatment of Moderate to Severe Pain in Pediatric Patients Presenting to the Emergency Department: a Prospective, Randomized, Double-blind Study Terminated NCT02388321 Phase 4 Ketamine;Fentanyl
31 Double-blind Cross-over Study of the Effect of Namenda on Short Term Memory and Attention in Patients With Mild to Moderate Traumatic Brain Injury, Protocol NAM-MD-44 Terminated NCT00462228 Phase 4 Memantine;Placebo
32 Interventional Study of Dexmedetomidine for Sedating Anticipated Difficult Airway Patients Undergoing Awake Fiberoptic Nasal Intubation Unknown status NCT00815893 Phase 2, Phase 3 dexmedetomidine;Normal Saline 0.9%;propofol 1%
33 A Prospective Multicenter Double Blind Randomized Controlled Trial to Explore the Tolerability, Safety and Efficacy of the H1-Coil Deep Transcranial Magnetic Stimulation (TMS) in Subjects With Schizophrenia Experiencing Auditory Hallucinations Unknown status NCT00564096 Phase 2, Phase 3
34 Magnetic Seizure Therapy (MST) for the Treatment of Severe Mood Disorder Completed NCT00488748 Phase 3
35 Comparison of Ketamine Versus Co-Administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department Completed NCT01387139 Phase 3 Ketamine;Ketamine Co-administered with Propofol
36 Focal Electrical Administered Seizure Therapy (FEAST) for Major Depression Completed NCT01589315 Phase 2, Phase 3
37 Combination Pharmacotherapy With Chantix & Bupropion for Smoking Cessation (ChanBan) Completed NCT00587769 Phase 3 Bupropion SR & Varenicline
38 Evaluation of an Active Strategy to Implement the Canadian CT Head Rule: Phase III Completed NCT00993252 Phase 3
39 A Study to Assess the Analgesia and Sedation Using Intranasal Dexmedetomidine in Third Molar Surgery Under Local Anaesthesia Completed NCT01132794 Phase 3 Intranasal dexmedetomidine;Placebo
40 Treatment Strategy to Prevent Mood Disorders Following Traumatic Brain Injury Completed NCT00704379 Phase 2, Phase 3 Placebo;Sertraline
41 A Randomized Controlled Non-inferiority Trial Comparing Ketamine With ECT in Patients With Major Depressive Disorder Completed NCT02659085 Phase 2, Phase 3 Ketamine IV Infusion
42 Focal Electrically-Administered Seizure Therapy (FEAST): Studies at Two Enrolling Sites to Further Test and Refine the Treatment Completed NCT02535572 Phase 2, Phase 3
43 Success of Sedation During Bronchoscopy: Comparison of the Effects of Dexmedetomidine, Alfentanil and Local Anesthesia Completed NCT01805726 Phase 3 xylocain;Alfentanil;Dexmedetomidine
44 A Randomized Double-blind Trial to Evaluate Ketamine-propofol Combination vs. Propofol Alone for Procedural Sedation and Analgesia in the Emergency Department. Completed NCT01211158 Phase 3 Ketofol;Propofol alone
45 An Open-Label, Randomised, Active Controlled, Multi-Centre Phase 3 Study to Evaluate the Safety and Efficacy of Danaparoid vs Argatroban in Treatment of Subjects With Acute HIT (HITSOVA Study) Active, not recruiting NCT03809481 Phase 3 Danaparoid Sodium;Argatroban
46 PCSK9 Inhibitor: a New Tool to Fight Septic Shock Not yet recruiting NCT03634293 Phase 2, Phase 3 Alirocumab Injectable Product;Saline Solution
47 A Phase III, Randomized, Open-label Study to Assess the Safety and Efficacy of AQUAVAN® Injection Versus Midazolam HCl for Sedation in Patients Undergoing Minor Surgical Procedures Terminated NCT00209560 Phase 3 fospropofol disodium
48 Sodium Butyrate As A Treatment For Improving Cognitive Function In Schizophrenia Withdrawn NCT02654405 Phase 2, Phase 3
49 Phase II Study of Rosuvastatin´s Effect on Amnesia and Orientation Through Galveston Outcome Amnesia Test in Humans With Moderate Head Injury Completed NCT00329758 Phase 2 rosuvastatin;Placebo
50 Effect of Rosuvastatin on Immunological Markers After Traumatic Brain Injury: Clinical Randomized Double Blind Study Phase 2 Completed NCT00990028 Phase 1, Phase 2 Rosuvastatin;Placebo

Search NIH Clinical Center for Amnestic Disorder

Cochrane evidence based reviews: amnesia

Genetic Tests for Amnestic Disorder

Anatomical Context for Amnestic Disorder

MalaCards organs/tissues related to Amnestic Disorder:

40
Brain, Testes, Temporal Lobe, Cortex, Amygdala, Thalamus, Spinal Cord

Publications for Amnestic Disorder

Articles related to Amnestic Disorder:

(show top 50) (show all 10083)
# Title Authors PMID Year
1
Cryptotanshinone, an acetylcholinesterase inhibitor from Salvia miltiorrhiza, ameliorates scopolamine-induced amnesia in Morris water maze task. 61 54
19774505 2010
2
Memory formation, amnesia, improved memory and reversed amnesia: 5-HT role. 54 61
18221797 2008
3
Antibodies to voltage-gated potassium and calcium channels in epilepsy. 61 54
16870397 2006
4
Study of PMS777, a new type of acetylcholinesterase inhibitor, in human HepG2 cells. Comparison with tacrine and galanthamine on oxidative stress and mitochondrial impairment. 61 54
16472967 2006
5
Unclosed beta-propellers display stable structures: implications for substrate access to the active site of prolyl oligopeptidase. 54 61
15713471 2005
6
The prolyl oligopeptidase family. 61 54
11915948 2002
7
Inhibition of passive-avoidance memory formation in the day-old chick by the opioid cytochrophin-4. 61 54
10940321 2000
8
Identification of the opioid receptors involved in passive-avoidance learning in the day-old chick during the second wave of neuronal activity. 61 54
10802030 2000
9
Improving effects of huperzine A on spatial working memory in aged monkeys and young adult monkeys with experimental cognitive impairment. 54 61
9918593 1999
10
Physiological, pathophysiological and therapeutic roles of 5-HT systems in learning and memory. 54 61
9886142 1998
11
[Biochemical studies on functional proteins in the brain nervous system. Neurobiochemical studies on nerve growth factor]. 54 61
8709005 1996
12
[The interaction of dopamine and opioid receptors in the re-establishing of an amnesic and forgotten memory trace by quinpirole]. 54 61
7773079 1995
13
Effects of nefiracetam, DM-9384 on amnesia and decrease in choline acetyltransferase activity induced by cycloheximide. 54 61
1463591 1992
14
[Experimental study of the effects of amiridin and tacrine on learning and memory]. 61 54
1893185 1991
15
Involvement of the cholinergic neuronal system and benzodiazepine receptors in alcohol-induced amnesia. 61 54
1651866 1991
16
The role of GABAA and GABAB receptors in the development of amnesia. 61 54
2177529 1990
17
Cholinergic receptor antagonists impair formation of intermediate-term memory in the chick. 54 61
2378607 1990
18
Differentiating psychogenic nonepileptic from epileptic seizures: A mixed-methods, content analysis study. 61
32388401 2020
19
Transient global amnesia following carotid artery stenting: A case report. 61
32528605 2020
20
Fat-1 expression enhance hippocampal memory in scopolamine-induced amnesia. 61
32454411 2020
21
Dissociation as a disorder of integration - On the footsteps of Pierre Janet. 61
32194203 2020
22
Recurrent transient global amnesia after intracavernous Caverject injection in erectile dysfunction after robotic prostatectomy. 61
32280597 2020
23
Dreaming with hippocampal damage. 61
32508305 2020
24
Sexual symptoms in post-traumatic stress disorder following childhood sexual abuse: a network analysis. 61
32517829 2020
25
The Susceptibility to Other Infectious Diseases Following Measles During a Three Year Observation Period in Switzerland. 61
32084116 2020
26
Return to Sport Following Adolescent Concussion: Epidemiologic Findings From a High School Population. 61
32501519 2020
27
Characterization and neuroprotective properties of alkaloid extract of Vernonia amygdalina Delile in experimental models of Alzheimer's disease. 61
32543989 2020
28
Dissecting the fornix in basic memory processes and neuropsychiatric disease: A review. 61
32567331 2020
29
[A case of herpes simplex virus encephalitis recurring after a seven-year interval]. 61
32536661 2020
30
Astrocytic BDNF and TrkB regulate severity and neuronal activity in mouse models of temporal lobe epilepsy. 61
32483154 2020
31
Imbalance in cerebral protein homeostasis: Effects on memory consolidation. 61
32535180 2020
32
A Prospective Study of Acute Blood-Based Biomarkers for Sport-Related Concussion. 61
32215965 2020
33
Epilepsy after severe traumatic brain injury: frequency and injury severity. 61
32506958 2020
34
Using the neutrophil-to-lymphocyte ratio to predict outcomes in pediatric patients with traumatic brain injury. 61
32155528 2020
35
A rare case of sever primary hypoparathyroidism presented with amnesia and basal ganglia calcification. 61
32550208 2020
36
Functional neurology after the Second World War: The beginnings of neurology on screen (III). 61
32467130 2020
37
Retained ability to extract gist in childhood-acquired amnesia: Insights from a single case. 61
32420799 2020
38
Double whammy: sex-related headache and amnesia. 61
30927160 2020
39
Transient epileptic amnesia with amygdala enlargement. 61
31858330 2020
40
Transient Epileptic Amnesia: Under-Diagnosed but Treatable Cause of Memory Dysfunction. 61
32502482 2020
41
Opiate analgesics and testing of post traumatic amnesia in school-aged children. 61
32497441 2020
42
A multicenter study of transient global amnesia for the better detection of magnetic resonance imaging abnormalities. 61
32558010 2020
43
An Unusual Presentation of Hereditary Angioedema Type II with Amnesia, Poor Concentration and Headache. 61
32565143 2020
44
Shedding light on the clinical recognition process of transient global amnesia. 61
32484252 2020
45
Diffusion-weighted MRI in transient global amnesia and its diagnostic implications. 61
32532848 2020
46
[Ictal EEG pattern of transient epileptic amnesia in acute phase of non-herpetic limbic encephalitis]. 61
32435050 2020
47
Any Recent Stressors?-A Memoir of Transient Global Amnesia. 61
32478803 2020
48
Acute amnestic syndromes. 61
32203745 2020
49
The neuroprotective effect of NeuroAid on morphine-induced amnesia with respect to the expression of TFAM, PGC-1α, ΔfosB and CART genes in the hippocampus of male Wistar rats. 61
32198124 2020
50
Exploring the relationship between auditory hallucinations, trauma and dissociation. 61
32431265 2020

Variations for Amnestic Disorder

Expression for Amnestic Disorder

Search GEO for disease gene expression data for Amnestic Disorder.

Pathways for Amnestic Disorder

Pathways related to Amnestic Disorder according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.37 TSPO PDYN OPRM1 OPRK1 OPRD1 HTR1A
2
Show member pathways
12.65 GRIN2B GAD1 GABRR3 CREB1 CHAT BCHE
3 12.17 OPRM1 HTR1A GRIN2B GAD1 CREB1 APP
4 12.11 HTR1A GRIN2B CREB1 BDNF
5 11.79 HTR3A HTR1A APP
6
Show member pathways
11.78 PDYN GRIN2B CREB1 BDNF
7
Show member pathways
11.67 PDYN GRIN2B CREB1
8
Show member pathways
11.6 TNFSF12 BDNF APP
9 11.57 GAD1 CHAT BDNF
10 11.23 HTR3A HTR1A CREB1 CHAT BDNF
11 11.05 OPRK1 GAD1 CREB1 BDNF
12 10.99 CHAT BCHE ACHE
13
Show member pathways
10.84 GAD1 CHAT ACHE
14 10.69 CREB1 BDNF
15 10.6 CHAT ACHE
16 10.3 CHAT ACHE

GO Terms for Amnestic Disorder

Cellular components related to Amnestic Disorder according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 10.3 TNFSF12 PDYN OPRM1 OPRK1 OPRD1 HTR3A
2 integral component of plasma membrane GO:0005887 9.97 TNFSF12 OPRM1 OPRK1 OPRD1 HTR3A HTR1A
3 dendrite GO:0030425 9.88 PDYN OPRM1 OPRK1 HTR1A BDNF
4 axon GO:0030424 9.85 OPRM1 HTR3A GAD1 CREB1 BDNF APP
5 postsynaptic membrane GO:0045211 9.76 OPRD1 HTR3A GRIN2B GABRR3
6 integral component of postsynaptic membrane GO:0099055 9.61 OPRM1 OPRK1 HTR3A
7 axon terminus GO:0043679 9.56 PDYN OPRK1 OPRD1 GAD1
8 neuron projection GO:0043005 9.56 OPRM1 OPRK1 OPRD1 HTR3A GRIN2B GABRR3
9 synaptic cleft GO:0043083 9.51 LGI1 ACHE
10 nuclear envelope lumen GO:0005641 9.49 BCHE APP
11 integral component of presynaptic membrane GO:0099056 9.46 OPRM1 OPRK1 OPRD1 HTR3A
12 spine apparatus GO:0097444 9.4 OPRM1 OPRD1
13 synapse GO:0045202 9.32 OPRK1 LGI1 HTR3A HTR1A GRIN2B GAD1

Biological processes related to Amnestic Disorder according to GeneCards Suite gene sharing:

(show all 26)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.19 TNFSF12 OPRM1 OPRK1 OPRD1 HTR3A HTR1A
2 nervous system development GO:0007399 10.01 LGI1 IMPACT BDNF APP ACHE
3 response to drug GO:0042493 9.91 TSPO GAD1 CREB1 BDNF BCHE
4 locomotory behavior GO:0007626 9.79 OPRM1 OPRK1 APP
5 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.78 OPRD1 BDNF APP
6 cellular response to growth factor stimulus GO:0071363 9.77 OPRD1 HTR3A CREB1
7 learning or memory GO:0007611 9.76 GRIN2B BDNF APP
8 excitatory postsynaptic potential GO:0060079 9.75 OPRM1 HTR3A GRIN2B
9 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 9.74 OPRM1 OPRD1 HTR1A
10 phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 9.73 OPRM1 OPRK1 OPRD1
11 response to ethanol GO:0045471 9.73 OPRM1 OPRK1 HTR3A GRIN2B
12 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0007193 9.72 OPRM1 OPRK1 OPRD1
13 neuropeptide signaling pathway GO:0007218 9.71 PDYN OPRM1 OPRK1 OPRD1
14 response to cocaine GO:0042220 9.7 OPRM1 OPRK1 HTR3A
15 response to radiation GO:0009314 9.67 OPRM1 OPRK1 APP
16 regulation of sensory perception of pain GO:0051930 9.65 OPRM1 OPRK1 OPRD1
17 estrous cycle GO:0044849 9.63 OPRM1 OPRK1
18 regulation of NMDA receptor activity GO:2000310 9.63 OPRM1 GRIN2B APP
19 behavior GO:0007610 9.62 OPRK1 HTR1A
20 serotonin receptor signaling pathway GO:0007210 9.59 HTR3A HTR1A
21 eating behavior GO:0042755 9.5 OPRM1 OPRK1 OPRD1
22 neurotransmitter biosynthetic process GO:0042136 9.43 GAD1 CHAT ACHE
23 adenylate cyclase-inhibiting opioid receptor signaling pathway GO:0031635 9.37 OPRM1 OPRK1
24 sensory perception GO:0007600 9.33 PDYN OPRM1 OPRK1
25 chemical synaptic transmission GO:0007268 9.17 PDYN OPRK1 HTR3A HTR1A GRIN2B GAD1
26 opioid receptor signaling pathway GO:0038003 9.13 OPRM1 OPRK1 OPRD1

Molecular functions related to Amnestic Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neurotransmitter receptor activity GO:0030594 9.61 HTR3A HTR1A GABRR3
2 amyloid-beta binding GO:0001540 9.58 GRIN2B BCHE ACHE
3 peptide binding GO:0042277 9.54 OPRM1 OPRK1 OPRD1
4 serotonin binding GO:0051378 9.48 HTR3A HTR1A
5 glutamate binding GO:0016595 9.46 GRIN2B GAD1
6 receptor serine/threonine kinase binding GO:0033612 9.32 OPRK1 OPRD1
7 cholinesterase activity GO:0004104 9.26 BCHE ACHE
8 acetylcholinesterase activity GO:0003990 9.16 BCHE ACHE
9 neuropeptide binding GO:0042923 9.13 OPRM1 OPRK1 OPRD1
10 opioid receptor activity GO:0004985 8.8 OPRM1 OPRK1 OPRD1

Sources for Amnestic Disorder

3 CDC
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10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
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30 HMDB
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61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
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72 UMLS via Orphanet
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