MCID: AMY002
MIFTS: 26

Amyloid Tumor

Categories: Cancer diseases
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Aliases & Classifications for Amyloid Tumor

MalaCards integrated aliases for Amyloid Tumor:

Name: Amyloid Tumor 11 14 71
Amyloid Neoplasm 11
Amyloid Tumour 11

Classifications:



External Ids:

Disease Ontology 11 DOID:6755
SNOMED-CT 68 37279009
UMLS 71 C0333572

Summaries for Amyloid Tumor

MalaCards based summary: Amyloid Tumor, also known as amyloid neoplasm, is related to amyloidosis and immunoglobulin light chain amyloidosis. An important gene associated with Amyloid Tumor is B2M (Beta-2-Microglobulin), and among its related pathways/superpathways is FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include breast, trachea and lung, and related phenotypes are Negative genetic interaction between PTTG1-/- and PTTG1+/+ and integument

Related Diseases for Amyloid Tumor

Diseases related to Amyloid Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 83)
# Related Disease Score Top Affiliating Genes
1 amyloidosis 30.5 TTR INS B2M
2 immunoglobulin light chain amyloidosis 30.4 TTR B2M
3 serum amyloid a amyloidosis 30.2 TTR B2M
4 carpal tunnel syndrome 29.7 TTR INS B2M
5 nephrotic syndrome 29.2 TTR INS B2M
6 bladder cancer 10.2
7 myeloma, multiple 10.1
8 pulmonary coin lesion 10.1 TTR B2M
9 asymmetric motor neuropathy 10.1 TTR B2M
10 hereditary amyloidosis 10.1 TTR B2M
11 wild-type amyloidosis 10.1 TTR B2M
12 dialysis-related amyloidosis 10.1 TTR B2M
13 amyloidosis, hereditary, transthyretin-related 10.0 TTR B2M
14 marasmus 10.0 TTR INS
15 pyelitis 10.0 INS B2M
16 kwashiorkor 10.0 TTR INS
17 diastolic heart failure 10.0 TTR INS
18 decubitus ulcer 10.0 TTR INS
19 amyloidosis, familial visceral 10.0 TTR B2M
20 beta-thalassemia major 10.0 INS B2M
21 chronic ulcer of skin 10.0 TTR INS
22 mononeuropathy of the median nerve, mild 10.0
23 lung benign neoplasm 10.0
24 plasmacytoma 10.0
25 mineral metabolism disease 10.0 INS B2M
26 hypertensive heart disease 10.0 TTR INS
27 autonomic nervous system disease 10.0 TTR INS
28 extramedullary plasmacytoma 9.9
29 teeth hard tissue disease 9.9 INS AMBN
30 autoimmune disease 9.9
31 lymphoma, hodgkin, classic 9.9
32 gastric cancer 9.9
33 lacrimal gland carcinoma 9.9
34 periarthritis 9.9
35 autonomic neuropathy 9.9 TTR INS
36 uremia 9.9 INS B2M
37 nerve compression syndrome 9.8 TTR INS B2M
38 heart valve disease 9.8 TTR INS
39 esophageal basaloid squamous cell carcinoma 9.8 LGALS7B LGALS7
40 lymph node carcinoma 9.8
41 urethritis 9.8
42 rectum cancer 9.8
43 bladder squamous cell carcinoma 9.8 LGALS7B LGALS7
44 uterus carcinoma in situ 9.8 LGALS7B LGALS7
45 chronic kidney disease 9.8 TTR INS B2M
46 heart conduction disease 9.8 TTR INS
47 cervix uteri carcinoma in situ 9.8 LGALS7B LGALS7
48 breast cancer 9.7
49 carcinoid tumors, intestinal 9.7
50 hashimoto thyroiditis 9.7

Graphical network of the top 20 diseases related to Amyloid Tumor:



Diseases related to Amyloid Tumor

Symptoms & Phenotypes for Amyloid Tumor

GenomeRNAi Phenotypes related to Amyloid Tumor according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Negative genetic interaction between PTTG1-/- and PTTG1+/+ GR00255-A-4 8.8 B2M INS TTR

MGI Mouse Phenotypes related to Amyloid Tumor:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.02 AMBN B2M INS LGALS7 LGALS7B

Drugs & Therapeutics for Amyloid Tumor

Search Clinical Trials, NIH Clinical Center for Amyloid Tumor

Genetic Tests for Amyloid Tumor

Anatomical Context for Amyloid Tumor

Organs/tissues related to Amyloid Tumor:

MalaCards : Breast, Trachea, Lung, Tongue, Colon, Appendix, Thyroid

Publications for Amyloid Tumor

Articles related to Amyloid Tumor:

(show top 50) (show all 197)
# Title Authors PMID Year
1
Orbital amyloid tumor associated with myasthenia gravis. 62
36075668 2022
2
Giant exophytic tumor of the leg: A case report of amyloidoma with literature review. 62
34673611 2021
3
Gangrenous ischaemic colitis following lung wedge resection. 62
31088812 2019
4
Amyloid tumor of the breast. 62
30783867 2019
5
Progression of dialysis-related amyloidoma towards pathologic fracture. 62
29946879 2019
6
[LOCALIZED AMYLOIDOSIS OF THE RENAL SINUS: A CASE REPORT]. 62
32684580 2019
7
SMASH-U versus H-ATOMIC: A Head-to-Head Comparison for the Etiologic Classification of Intracerebral Hemorrhage. 62
29779884 2018
8
Efficacy of anakinra in a patient with systemic amyloidosis presenting as amyloidoma. 62
29239128 2018
9
Benign osseous metaplasia of the breast: Case report. 62
29482081 2018
10
Incidental Discovery of Multiple Myeloma, Presenting as an Amyloid Tumor with Plasmacytic Elements of the Thoracic Wall. 62
26710503 2015
11
Amyloidosis of the Breast: Three Different and Unusual Presentations of a Rare Entity. 62
26513367 2015
12
Calcified amyloid tumor of neck with exuberant giant cell reaction. 62
25949063 2015
13
Prostate amyloid tumor is a clue leading to the diagnosis of systemic AL amyloidosis. 62
23826754 2013
14
Amyloid tumor behaving as localized amyloidosis in a patient with long history of asymptomatic light chain myeloma. 62
23882901 2013
15
Isolated pulmonary amyloidomas: report of 3 cases with histologic and imaging findings. 62
23218762 2013
16
Oral soft tissue alterations in patients with neurofibromatosis. 62
21301902 2012
17
Intraocular ALĪ» amyloidoma with plasma cell neoplasia in a cat. 62
21923829 2011
18
[Amyloidosis--diagnostic difficulties. A case report of localized amyloidosis]. 62
22335145 2011
19
Amyloid tumour. 62
19344394 2010
20
Human recombinant insulin and amyloidosis: an unexpected association. 62
20308712 2010
21
Nasopharyngeal amyloidosis: an unusual cause for epistaxis. 62
19527533 2010
22
Jejunal Amyloidoma - a rare cause of gastrointestinal bleeding. 62
20062677 2009
23
Soft-tissue amyloidoma of the extremities: a case report and review of literature. 62
19050870 2009
24
Amyloid tumor of the stomach simulating an obstructing gastric carcinoma: case report and review of the literature. 62
19288419 2009
25
Solitary amyloid tumor of the tongue base. 62
20107570 2009
26
Intracranial Aspergillus infection associated with an amyloid tumor and lymphoma. 62
19412411 2008
27
Amyloid tumor of the breast mimicking breast carcinoma. 62
18364625 2008
28
Laryngeal plasmacytoma presenting as amyloid tumour: a case report. 62
17431662 2007
29
Genital beta2-microglobulin amyloidoma in a long-term dialysis patient. 62
16931206 2006
30
Tumoral, quasitumoral and pseudotumoral lesions of the superficial and somatic soft tissue: new entities and new variants of old entities recorded during the last 25 years. Part XII: appendix. 62
17175794 2006
31
Lacrimal gland amyloidosis. 62
16855510 2006
32
Lung osteoma--a new benign lung lesion. 62
16639606 2006
33
Collapse in a 79-year-old: a rare case of amyloid tumour of the pelvis. 62
16267196 2005
34
Amyloid tumor of the larynx associated with plasma cell infiltration: differential diagnosis. 62
15724743 2004
35
Aspiration cytology diagnosis of a primary amyloid tumor of thoracic vertebra: a case report. 62
15282731 2004
36
Fine needle aspiration cytology of a primary amyloid tumor of the breast. 62
15085770 2004
37
Amyloid tumor in the anterior mediastinum: report of a case. 62
15170548 2004
38
Solitary amyloid tumour of breast--a case report. 62
15025361 2003
39
Aspiration cytology diagnosis of a primary amyloid tumor of thoracic vertebra: a case report. 62
12951685 2003
40
Amyloid tumor: a clinical and cytomorphologic study. 62
12768639 2003
41
Isolated amyloid tumor in the mediastinum: report of a case. 62
12658387 2003
42
Primary amyloid tumour of the breast: a case report. 62
12147664 2002
43
Amyloid tumour of the breast mimicking carcinoma. 62
12269899 2002
44
AA-type amyloid tumor as an unsuspected cause of residual mass in a patient with large B-cell non-Hodgkin's lymphoma. 62
12002783 2002
45
Extramedullary plasmacytoma of the parotid gland. Report of a case with extensive amyloid deposition masking the cytologic and histopathologic picture. 62
11393084 2001
46
Aspiration biopsy findings in amyloid tumor of the cervical vertebra. A case report. 62
11393073 2001
47
[Isolated idiopathic amyloid tumor of the sacrum. An important differential diagnosis]. 62
11353907 2001
48
Primary localized amyloidosis of the urinary bladder. A case report. 62
11930833 2001
49
Localized amyloid tumor in small bowel. 62
11052330 2000
50
Bilateral metachronous periosteal tibial amyloid tumors. 62
10929417 2000

Variations for Amyloid Tumor

Expression for Amyloid Tumor

Search GEO for disease gene expression data for Amyloid Tumor.

Pathways for Amyloid Tumor

Pathways related to Amyloid Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.26 TTR INS

GO Terms for Amyloid Tumor

Cellular components related to Amyloid Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum lumen GO:0005788 9.63 INS B2M AMBN
2 extracellular space GO:0005615 9.61 TTR LGALS7B LGALS7 INS B2M
3 extracellular region GO:0005576 9.32 TTR LGALS7B LGALS7 INS B2M AMBN

Biological processes related to Amyloid Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 9.33 LGALS7B LGALS7
2 negative regulation of type II interferon production GO:0032689 9.13 LGALS7B LGALS7
3 negative regulation of CD4-positive, alpha-beta T cell proliferation GO:2000562 8.8 LGALS7B LGALS7

Molecular functions related to Amyloid Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 galactoside binding GO:0016936 8.8 LGALS7B LGALS7

Sources for Amyloid Tumor

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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