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MCID: AMY002
MIFTS: 26

Amyloid Tumor

Categories: Cancer diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Amyloid Tumor

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MalaCards integrated aliases for Amyloid Tumor:

Name: Amyloid Tumor 12 15 70
Amyloid Neoplasm 12
Amyloid Tumour 12

Classifications:

MalaCards categories:
Global: Cancer diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:6755
SNOMED-CT 67 37279009
UMLS 70 C0333572
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Summaries for Amyloid Tumor

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MalaCards based summary : Amyloid Tumor, also known as amyloid neoplasm, is related to al amyloidosis and amyloidosis. An important gene associated with Amyloid Tumor is B2M (Beta-2-Microglobulin), and among its related pathways/superpathways is FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include tongue, kidney and trachea, and related phenotype is Negative genetic interaction between PTTG1-/- and PTTG1+/+.

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Related Diseases for Amyloid Tumor

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Diseases related to Amyloid Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 78)
# Related Disease Score Top Affiliating Genes
1 al amyloidosis 30.0 TTR B2M
2 amyloidosis 30.0 TTR MYOM2 INS B2M
3 extramedullary plasmacytoma 29.9 MYOM2 B2M
4 amyloidosis aa 29.8 TTR B2M
5 carpal tunnel syndrome 29.7 TTR INS B2M
6 kidney disease 29.2 TTR INS B2M
7 asymmetric motor neuropathy 10.1 TTR B2M
8 hereditary amyloidosis 10.1 TTR B2M
9 amyloidosis, hereditary, transthyretin-related 10.1 TTR B2M
10 papillary ependymoma 10.1 TTR NF2
11 marasmus 10.1 TTR INS
12 pyelitis 10.1 INS B2M
13 kwashiorkor 10.0 TTR INS
14 solitary osseous plasmacytoma 10.0 MYOM2 B2M
15 decubitus ulcer 10.0 TTR INS
16 non-secretory myeloma 10.0 MYOM2 B2M
17 cerebral ventricle cancer 10.0 TTR NF2
18 cerebrum cancer 10.0 TTR NF2
19 chronic ulcer of skin 10.0 TTR INS
20 proteinuria, chronic benign 10.0 INS B2M
21 autonomic nervous system disease 10.0 TTR INS
22 smoldering myeloma 10.0 MYOM2 B2M
23 mixed cerebral palsy 10.0 TTR MYOM2
24 amyloidosis, familial visceral 10.0 TTR B2M
25 lymphoplasmacytic lymphoma 10.0 MYOM2 B2M
26 myeloma, multiple 10.0
27 plasma protein metabolism disease 10.0 MYOM2 B2M
28 monoclonal gammopathy of uncertain significance 10.0 MYOM2 B2M
29 waldenstroem's macroglobulinemia 10.0 MYOM2 B2M
30 blood protein disease 9.9 MYOM2 B2M
31 cellulitis 9.9 MYOM2 INS
32 autonomic neuropathy 9.9 TTR INS
33 uremia 9.9 INS B2M
34 periarthritis 9.9
35 plasmacytoma 9.9
36 mature b-cell neoplasm 9.9 MYOM2 B2M
37 nerve compression syndrome 9.8 TTR INS B2M
38 end stage renal disease 9.8 TTR INS B2M
39 leukocyte disease 9.8 MYOM2 B2M
40 lymph node carcinoma 9.8
41 urethritis 9.8
42 contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a 9.8 TTR NF2 INS
43 autosomal genetic disease 9.8 TTR NF2 INS
44 mineral metabolism disease 9.8 MYOM2 INS B2M
45 autoimmune disease 9.7
46 sjogren syndrome 9.7
47 thymoma, familial 9.7
48 meningioma, familial 9.7
49 fibroma 9.7
50 intracranial meningioma 9.7

Graphical network of the top 20 diseases related to Amyloid Tumor:



Diseases related to Amyloid Tumor
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Symptoms & Phenotypes for Amyloid Tumor

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GenomeRNAi Phenotypes related to Amyloid Tumor according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Negative genetic interaction between PTTG1-/- and PTTG1+/+ GR00255-A-4 8.92 B2M INS MYOM2 TTR
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Drugs & Therapeutics for Amyloid Tumor

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Search Clinical Trials , NIH Clinical Center for Amyloid Tumor

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Genetic Tests for Amyloid Tumor

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Anatomical Context for Amyloid Tumor

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MalaCards organs/tissues related to Amyloid Tumor:

40
Tongue, Kidney, Trachea, Colon, Breast, Spleen, Skin
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Publications for Amyloid Tumor

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Articles related to Amyloid Tumor:

(show top 50) (show all 195)
# Title Authors PMID Year
1
Gangrenous ischaemic colitis following lung wedge resection. 61
31088812 2019
2
Amyloid tumor of the breast. 61
30783867 2019
3
Progression of dialysis-related amyloidoma towards pathologic fracture. 61
29946879 2019
4
[LOCALIZED AMYLOIDOSIS OF THE RENAL SINUS: A CASE REPORT]. 61
32684580 2019
5
SMASH-U versus H-ATOMIC: A Head-to-Head Comparison for the Etiologic Classification of Intracerebral Hemorrhage. 61
29779884 2018
6
Efficacy of anakinra in a patient with systemic amyloidosis presenting as amyloidoma. 61
29239128 2018
7
Benign osseous metaplasia of the breast: Case report. 61
29482081 2018
8
Incidental Discovery of Multiple Myeloma, Presenting as an Amyloid Tumor with Plasmacytic Elements of the Thoracic Wall. 61
26710503 2015
9
Amyloidosis of the Breast: Three Different and Unusual Presentations of a Rare Entity. 61
26513367 2015
10
Calcified amyloid tumor of neck with exuberant giant cell reaction. 61
25949063 2015
11
Prostate amyloid tumor is a clue leading to the diagnosis of systemic AL amyloidosis. 61
23826754 2013
12
Amyloid tumor behaving as localized amyloidosis in a patient with long history of asymptomatic light chain myeloma. 61
23882901 2013
13
Isolated pulmonary amyloidomas: report of 3 cases with histologic and imaging findings. 61
23218762 2013
14
Oral soft tissue alterations in patients with neurofibromatosis. 61
21301902 2012
15
Intraocular ALλ amyloidoma with plasma cell neoplasia in a cat. 61
21923829 2011
16
[Amyloidosis--diagnostic difficulties. A case report of localized amyloidosis]. 61
22335145 2011
17
Amyloid tumour. 61
19344394 2010
18
Human recombinant insulin and amyloidosis: an unexpected association. 61
20308712 2010
19
Nasopharyngeal amyloidosis: an unusual cause for epistaxis. 61
19527533 2010
20
Jejunal Amyloidoma - a rare cause of gastrointestinal bleeding. 61
20062677 2009
21
Soft-tissue amyloidoma of the extremities: a case report and review of literature. 61
19050870 2009
22
Amyloid tumor of the stomach simulating an obstructing gastric carcinoma: case report and review of the literature. 61
19288419 2009
23
Solitary amyloid tumor of the tongue base. 61
20107570 2009
24
Intracranial Aspergillus infection associated with an amyloid tumor and lymphoma. 61
19412411 2008
25
Amyloid tumor of the breast mimicking breast carcinoma. 61
18364625 2008
26
Laryngeal plasmacytoma presenting as amyloid tumour: a case report. 61
17431662 2007
27
Genital beta2-microglobulin amyloidoma in a long-term dialysis patient. 61
16931206 2006
28
Tumoral, quasitumoral and pseudotumoral lesions of the superficial and somatic soft tissue: new entities and new variants of old entities recorded during the last 25 years. Part XII: appendix. 61
17175794 2006
29
Lung osteoma--a new benign lung lesion. 61
16639606 2006
30
Lacrimal gland amyloidosis. 61
16855510 2006
31
Collapse in a 79-year-old: a rare case of amyloid tumour of the pelvis. 61
16267196 2005
32
Amyloid tumor of the larynx associated with plasma cell infiltration: differential diagnosis. 61
15724743 2004
33
Aspiration cytology diagnosis of a primary amyloid tumor of thoracic vertebra: a case report. 61
15282731 2004
34
Fine needle aspiration cytology of a primary amyloid tumor of the breast. 61
15085770 2004
35
Amyloid tumor in the anterior mediastinum: report of a case. 61
15170548 2004
36
Solitary amyloid tumour of breast--a case report. 61
15025361 2003
37
Aspiration cytology diagnosis of a primary amyloid tumor of thoracic vertebra: a case report. 61
12951685 2003
38
Amyloid tumor: a clinical and cytomorphologic study. 61
12768639 2003
39
Isolated amyloid tumor in the mediastinum: report of a case. 61
12658387 2003
40
Primary amyloid tumour of the breast: a case report. 61
12147664 2002
41
Amyloid tumour of the breast mimicking carcinoma. 61
12269899 2002
42
AA-type amyloid tumor as an unsuspected cause of residual mass in a patient with large B-cell non-Hodgkin's lymphoma. 61
12002783 2002
43
Extramedullary plasmacytoma of the parotid gland. Report of a case with extensive amyloid deposition masking the cytologic and histopathologic picture. 61
11393084 2001
44
Aspiration biopsy findings in amyloid tumor of the cervical vertebra. A case report. 61
11393073 2001
45
[Isolated idiopathic amyloid tumor of the sacrum. An important differential diagnosis]. 61
11353907 2001
46
Primary localized amyloidosis of the urinary bladder. A case report. 61
11930833 2001
47
Localized amyloid tumor in small bowel. 61
11052330 2000
48
Bilateral metachronous periosteal tibial amyloid tumors. 61
10929417 2000
49
Localized amyloid tumor of the nasopharynx. 61
10652414 2000
50
Amyloid tumour (amyloidoma) of the leg: histology, immunohistochemistry and electron microscopy. 61
10460669 1999
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Variations for Amyloid Tumor

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Expression for Amyloid Tumor

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Search GEO for disease gene expression data for Amyloid Tumor.
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Pathways for Amyloid Tumor

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Pathways related to Amyloid Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
FOXA2 and FOXA3 transcription factor networks 1
10.27 TTR INS
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GO Terms for Amyloid Tumor

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Biological processes related to Amyloid Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 9.33 TTR CR1 B2M
2 positive regulation of cell differentiation GO:0045597 8.96 NF2 INS
3 cellular protein metabolic process GO:0044267 8.8 TTR INS B2M

Molecular functions related to Amyloid Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 TTR INS
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Sources for Amyloid Tumor

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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