MCID: AMY002
MIFTS: 31

Amyloid Tumor

Categories: Cancer diseases

Aliases & Classifications for Amyloid Tumor

MalaCards integrated aliases for Amyloid Tumor:

Name: Amyloid Tumor 12 15 74
Amyloid Neoplasm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6755
SNOMED-CT 69 37279009
UMLS 74 C0333572

Summaries for Amyloid Tumor

MalaCards based summary : Amyloid Tumor, also known as amyloid neoplasm, is related to al amyloidosis and thyroiditis. An important gene associated with Amyloid Tumor is B2M (Beta-2-Microglobulin), and among its related pathways/superpathways are Neuroscience and FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include thyroid, breast and bone, and related phenotypes are homeostasis/metabolism and integument

Related Diseases for Amyloid Tumor

Diseases related to Amyloid Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)
# Related Disease Score Top Affiliating Genes
1 al amyloidosis 30.0 B2M TTR
2 thyroiditis 29.4 CALCA TG
3 tibial neuropathy 10.4 B2M TTR
4 tarsal tunnel syndrome 10.3 B2M TTR
5 median rhomboid glossitis 10.3 B2M TTR
6 hereditary amyloidosis 10.3 B2M TTR
7 nerve compression syndrome 10.3 B2M TTR
8 amyloidosis aa 10.3 B2M TTR
9 retinitis pigmentosa 7 10.3 B2M TTR
10 indolent myeloma 10.3 B2M MYOM2
11 extramedullary plasmacytoma 10.3 B2M MYOM2
12 waldenstroem's macroglobulinemia 10.3 B2M MYOM2
13 non-secretory myeloma 10.3 B2M MYOM2
14 solitary osseous plasmacytoma 10.3 B2M MYOM2
15 osteitis fibrosa 10.2 B2M CALCA
16 monoclonal gammopathy of uncertain significance 10.2 B2M MYOM2
17 chronic pyelonephritis 10.2 B2M CALCA
18 amyloidosis, familial visceral 10.2 B2M TTR
19 anterior scleritis 10.2 B2M IL1RN
20 cloacogenic carcinoma 10.2 B2M CALCA
21 carpal tunnel syndrome 10.2 B2M TTR
22 autonomic nervous system disease 10.2 CALCA TTR
23 mature b-cell neoplasm 10.2 B2M MYOM2
24 impetigo 10.2 CALCA MYOM2
25 neurofibroma 10.1 NF1 NF2
26 neurofibromatosis, familial spinal 10.1 NF1 NF2
27 osteosclerotic myeloma 10.1 IL1RN MYOM2
28 plexiform schwannoma 10.1 NF1 NF2
29 ependymoma 10.1 NF2 TTR
30 necrotizing fasciitis 10.1 IL1RN MYOM2
31 immature cataract 10.1 NF1 NF2
32 neurofibrosarcoma 10.1 NF1 NF2
33 acute cholangitis 10.1 CALCA IL1RN
34 plexiform neurofibroma 10.1 NF1 NF2
35 fibrous dysplasia 10.1 CALCA SPARC
36 atypical neurofibroma 10.1 NF1 NF2
37 neuroma 10.1 CALCA NF2
38 trigeminal nerve neoplasm 10.1 NF1 NF2
39 neurilemmoma 10.1 NF1 NF2
40 neurilemmoma of the fifth cranial nerve 10.1 NF1 NF2
41 chronic polyneuropathy 10.1 MYOM2 NF1
42 neurilemmomatosis 10.1 NF1 NF2
43 optic nerve neoplasm 10.1 NF1 NF2
44 hypersensitivity reaction type iv disease 10.1 IL1RN MYOM2
45 duodenal somatostatinoma 10.1 CALCA NF1
46 osteofibrous dysplasia 10.1 NF1 SPARC
47 aseptic meningitis 10.1 CALCA IL1RN
48 acoustic neuroma 10.1 NF1 NF2
49 giant cell reparative granuloma 10.1 CALCA NF1
50 root resorption 10.1 CALCA IL1RN

Graphical network of the top 20 diseases related to Amyloid Tumor:



Diseases related to Amyloid Tumor

Symptoms & Phenotypes for Amyloid Tumor

MGI Mouse Phenotypes related to Amyloid Tumor:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.5 B2M IL1RN NF1 NF2 SPARC TG
2 integument MP:0010771 9.02 B2M IL1RN NF1 NF2 SPARC

Drugs & Therapeutics for Amyloid Tumor

Search Clinical Trials , NIH Clinical Center for Amyloid Tumor

Genetic Tests for Amyloid Tumor

Anatomical Context for Amyloid Tumor

MalaCards organs/tissues related to Amyloid Tumor:

42
Thyroid, Breast, Bone, Lung, Tongue, Trachea, Spleen

Publications for Amyloid Tumor

Articles related to Amyloid Tumor:

(show top 50) (show all 70)
# Title Authors Year
1
Amyloid tumor of the breast. ( 30783867 )
2019
2
Calcified amyloid tumor of neck with exuberant giant cell reaction. ( 25949063 )
2015
3
Incidental Discovery of Multiple Myeloma, Presenting as an Amyloid Tumor with Plasmacytic Elements of the Thoracic Wall. ( 26710503 )
2015
4
Prostate amyloid tumor is a clue leading to the diagnosis of systemic AL amyloidosis. ( 23826754 )
2013
5
Amyloid tumor behaving as localized amyloidosis in a patient with long history of asymptomatic light chain myeloma. ( 23882901 )
2013
6
Amyloid tumor of the stomach simulating an obstructing gastric carcinoma: case report and review of the literature. ( 19288419 )
2009
7
Solitary amyloid tumor of the tongue base. ( 20107570 )
2009
8
Amyloid tumor of the breast mimicking breast carcinoma. ( 18364625 )
2008
9
Intracranial Aspergillus infection associated with an amyloid tumor and lymphoma. ( 19412411 )
2008
10
Fine needle aspiration cytology of a primary amyloid tumor of the breast. ( 15085770 )
2004
11
Amyloid tumor in the anterior mediastinum: report of a case. ( 15170548 )
2004
12
Aspiration cytology diagnosis of a primary amyloid tumor of thoracic vertebra: a case report. ( 15282731 )
2004
13
Amyloid tumor of the larynx associated with plasma cell infiltration: differential diagnosis. ( 15724743 )
2004
14
Isolated amyloid tumor in the mediastinum: report of a case. ( 12658387 )
2003
15
Amyloid tumor: a clinical and cytomorphologic study. ( 12768639 )
2003
16
Aspiration cytology diagnosis of a primary amyloid tumor of thoracic vertebra: a case report. ( 12951685 )
2003
17
AA-type amyloid tumor as an unsuspected cause of residual mass in a patient with large B-cell non-Hodgkin's lymphoma. ( 12002783 )
2002
18
Aspiration biopsy findings in amyloid tumor of the cervical vertebra. A case report. ( 11393073 )
2001
19
Localized amyloid tumor of the nasopharynx. ( 10652414 )
2000
20
Localized amyloid tumor in small bowel. ( 11052330 )
2000
21
Primary amyloid tumor (amyloidoma) of the jejunum with spheroid type of amyloid. ( 10212914 )
1999
22
Primary amyloidoma (amyloid tumor) of soft tissue. ( 9622729 )
1998
23
Intraabdominal immunoglobulin light chain amyloid tumor encompassing a vascular malformation. ( 9625589 )
1998
24
Primary localized amyloid tumor of the breast with osseous metaplasia. ( 9701018 )
1998
25
Localized amyloid tumor of the tongue. A case report and review of the literature. ( 15678860 )
1998
26
Primary amyloid tumor of the breast: a case report and review of the literature. ( 9237186 )
1997
27
Clinical and computed tomographic characteristics of amyloid tumor of the lacrimal gland. ( 8764792 )
1996
28
Recurrent amyloid tumor of the parotid gland. ( 7536425 )
1995
29
Amyloid tumor of the sacrum. A case report. ( 7762341 )
1995
30
Ga-67 and Tc-99m (V) DMSA imaging in non-Hodgkin's lymphoma with amyloid tumor. ( 8565385 )
1995
31
Localized primary amyloid tumor associated with osseous metaplasia presenting as bilateral breast masses: cytologic and radiologic features. ( 8287770 )
1993
32
Localized primary amyloid tumor of the thyroid developing in the course of Hashimoto's thyroiditis. ( 1570743 )
1992
33
[Craniocervical amyloid tumor with destructive spondyloarthropathy and myelocompression as a rare complication of long-term dialysis]. ( 2108522 )
1990
34
Subcutaneous amyloid-tumor of beta-2-microglobulin origin in a long-term hemodialysis patient. ( 2674745 )
1989
35
Localized primary amyloid tumor of the parotid gland. ( 3186222 )
1988
36
Case report 480: Periosteal amyloid tumor. ( 3375853 )
1988
37
Amyloid tumor of the spleen. ( 3307463 )
1987
38
Amyloid tumor (amyloidoma) of a peripheral nerve. ( 3021087 )
1986
39
Localized primary (AL) amyloid tumor of the breast. Cytologic, histologic, immunocytochemical and ultrastructural observations. ( 3526931 )
1986
40
Primary amyloid tumor of the breast. Case report and literature review. ( 3855589 )
1985
41
Primary amyloid tumor of the lacrimal gland: CT findings. ( 6630639 )
1983
42
Amyloid tumor of the breast. ( 6831938 )
1983
43
Case report 233. Amyloid tumor of the sternum as part of a solitary plasmacytoma. ( 6879219 )
1983
44
Amyloid tumor of the breast. ( 7166121 )
1982
45
Amyloid tumor of the orbit. ( 492520 )
1979
46
Amyloid tumor. A clinicopathologic study of four cases. ( 148847 )
1978
47
A case of amyloid tumor of the stomach. ( 631096 )
1978
48
Case report. Localized amyloid tumor of the bladder presenting as an anterior pelvic mass. ( 1155740 )
1975
49
Amyloid tumor of the breast. ( 4683157 )
1973
50
Intrasellar amyloid tumor. ( 4114837 )
1972

Variations for Amyloid Tumor

Expression for Amyloid Tumor

Search GEO for disease gene expression data for Amyloid Tumor.

Pathways for Amyloid Tumor

Pathways related to Amyloid Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.67 CALCA NF1 NF2
2 10.27 NF1 TTR

GO Terms for Amyloid Tumor

Cellular components related to Amyloid Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.35 B2M CALCA IL1RN SPARC TTR
2 extracellular region GO:0005576 9.1 B2M CALCA IL1RN SPARC TG TTR

Biological processes related to Amyloid Tumor according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.63 B2M CALCA TTR
2 extracellular matrix organization GO:0030198 9.61 NF1 SPARC TTR
3 pigmentation GO:0043473 9.49 NF1 SPARC
4 negative regulation of endothelial cell proliferation GO:0001937 9.48 NF1 SPARC
5 negative regulation of MAPK cascade GO:0043409 9.4 NF1 NF2
6 response to cadmium ion GO:0046686 9.37 B2M SPARC
7 regulation of cell proliferation GO:0042127 9.33 NF1 NF2 SPARC
8 negative regulation of osteoclast differentiation GO:0045671 9.32 CALCA NF1
9 negative regulation of cell-matrix adhesion GO:0001953 9.26 NF1 NF2
10 regulation of signaling receptor activity GO:0010469 9.26 CALCA IL1RN TG TTR
11 negative regulation of cell migration GO:0030336 8.62 NF1 NF2

Molecular functions related to Amyloid Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.8 CALCA TG TTR

Sources for Amyloid Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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