MCID: AMY009
MIFTS: 55

Amyloidosis Aa

Categories: Blood diseases, Bone diseases, Genetic diseases, Immune diseases, Metabolic diseases, Nephrological diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Amyloidosis Aa

MalaCards integrated aliases for Amyloidosis Aa:

Name: Amyloidosis Aa 54
Aa Amyloidosis 54 60 30 74
Amyloidosis, Secondary, Susceptibility to 13
Reactive Systemic Amyloidosis 74
Inflammatory Amyloidosis 60
Amyloid a Amyloidosis 54
Secondary Amyloidosis 60
Amyloidosis Secondary 56
Reactive Amyloidosis 60

Characteristics:

Orphanet epidemiological data:

60
aa amyloidosis
Inheritance: Multigenic/multifactorial;

Classifications:



Summaries for Amyloidosis Aa

NIH Rare Diseases : 54 Amyloidosis is a group of diseases in which a protein, called amyloid, builds up in the body's organs and tissues. Amyloidosis AA is also referred to as Secondary amyloidosis or Inflammatory amyloidosis. This disease is caused by a long-lasting infection or inflammatory disease such as rheumatoid arthritis, familial Mediterranean fever, or osteomyelitis. Infection or inflammation in the body causes an increased amount of a specific protein called serum amyloid A (SAA) protein. In this disease, part of the SAA protein forms deposits called "amyloid fibrils". These desposits occur in the space around the cells of certain tissues of the body. Amyloidosis AA usually begins as a disease in the kidneys, but other organs can be affected such as the liver and spleen. Medical or surgical treatment of the underlying infection or inflammatory disease can slow down or stop the progression of this condition.

MalaCards based summary : Amyloidosis Aa, also known as aa amyloidosis, is related to amyloidosis, hereditary, transthyretin-related and muckle-wells syndrome. An important gene associated with Amyloidosis Aa is SAA1 (Serum Amyloid A1), and among its related pathways/superpathways are Selenium Micronutrient Network and Statin Pathway. The drugs Creatine and Doxycycline have been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and heart, and related phenotypes are hypotension and proteinuria

Wikipedia : 77 AA amyloidosis is a form of amyloidosis, a disease characterized by the abnormal deposition of fibers of... more...

Related Diseases for Amyloidosis Aa

Diseases in the Amyloidosis family:

Amyloidosis, Hereditary, Transthyretin-Related Al Amyloidosis
Amyloidosis Aa Hereditary Amyloidosis
Primary Localized Amyloidosis Ah Amyloidosis

Diseases related to Amyloidosis Aa via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 272, show less)
# Related Disease Score Top Affiliating Genes
1 amyloidosis, hereditary, transthyretin-related 32.2 APOA1 TTR
2 muckle-wells syndrome 32.2 CRP MEFV
3 familial mediterranean fever 30.5 CRP MEFV SAA1 SAA2 SAA4
4 cryopyrin-associated periodic syndrome 30.5 CRP SAA4
5 al amyloidosis 30.4 B2M TTR
6 polyarteritis nodosa 30.3 CRP MEFV
7 hyper-igd syndrome 30.2 CRP SAA1
8 adult-onset still's disease 30.0 CRP MEFV
9 hypersensitivity vasculitis 29.8 CRP MEFV
10 wells syndrome 29.8 CRP MEFV
11 amyloidosis 29.6 APOA1 B2M MEFV SAA1 SAA2 SAA4
12 chronic kidney failure 29.1 B2M CRP LPA TTR
13 kidney disease 29.0 B2M CRP LCAT LPA TTR
14 lipid metabolism disorder 29.0 APOA1 CRP LCAT LPA
15 myeloma, multiple 10.8
16 arthritis 10.7
17 rheumatoid arthritis 10.6
18 unicentric castleman disease 10.3 CRP SAA4
19 bronchus cancer 10.3 CRP SAA1
20 wild type abeta2m amyloidosis 10.3
21 blepharochalasis 10.3 SAA1 TTR
22 relapsing fever 10.3 CRP MEFV
23 pericardium disease 10.3 CRP MEFV
24 hypersensitivity reaction type iii disease 10.2 CRP MEFV
25 decubitus ulcer 10.2 CRP TTR
26 pharyngitis 10.2 CRP MEFV
27 henoch-schoenlein purpura 10.2 CRP MEFV
28 tibial neuropathy 10.2 B2M TTR
29 tarsal tunnel syndrome 10.2 B2M TTR
30 pyelitis 10.2 B2M CRP
31 median rhomboid glossitis 10.2 B2M TTR
32 renal tuberculosis 10.2 B2M CRP
33 amyloid tumor 10.2 B2M TTR
34 nerve compression syndrome 10.2 B2M TTR
35 palindromic rheumatism 10.2 CRP MEFV
36 systemic lupus erythematosus 10.2
37 glomerulonephritis 10.2
38 rheumatic disease 10.2
39 lupus erythematosus 10.2
40 analbuminemia 10.2 CRP TTR
41 dysentery 10.2 CRP TTR
42 retinitis pigmentosa 7 10.2 B2M TTR
43 kwashiorkor 10.2 LCAT TTR
44 ischemic heart disease 10.2 APOA1 CRP
45 pleurisy 10.2 CRP MEFV
46 brucellosis 10.2 CRP MEFV SAA1
47 apo a-i deficiency 10.1 APOA1 LCAT
48 psoriatic arthritis 10.1
49 protein-losing enteropathy 10.1
50 diarrhea 10.1
51 adenoma 10.1
52 familial lcat deficiency 10.1 APOA1 LCAT
53 hemorrhagic fever with renal syndrome 10.1 B2M CRP
54 fish-eye disease 10.1 APOA1 LCAT
55 pericarditis 10.1 CRP MEFV
56 heart conduction disease 10.1 CRP TTR
57 fetal macrosomia 10.1 APOA1 LCAT
58 hypoalphalipoproteinemia, primary 10.0 APOA1 LCAT
59 peritonitis 10.0 B2M CRP MEFV
60 spondyloarthropathy 1 10.0
61 renal cell carcinoma, nonpapillary 10.0
62 cystic fibrosis 10.0
63 langerhans cell histiocytosis 10.0
64 leptin deficiency or dysfunction 10.0
65 diabetes mellitus 10.0
66 hepatocellular adenoma 10.0
67 acute pancreatitis 10.0
68 histiocytosis 10.0
69 pancreatitis 10.0
70 spondylitis 10.0
71 juvenile rheumatoid arthritis 10.0
72 vasculitis 10.0
73 macroglobulinemia 10.0
74 testicular yolk sac tumor 10.0 APOA1 TTR
75 carotenemia 10.0 LPA TTR
76 pyelonephritis 10.0
77 acquired metabolic disease 10.0 APOA1 CRP TTR
78 xanthogranulomatous pyelonephritis 9.9
79 hyperalphalipoproteinemia 1 9.9 APOA1 LCAT
80 coronary stenosis 9.9 APOA1 CRP
81 hereditary amyloidosis 9.9 APOA1 B2M TTR
82 lipoprotein glomerulopathy 9.9 LCAT LPA
83 leukodystrophy, hypomyelinating, 3 9.9 APOA1 LPA
84 hyperlipidemia, familial combined 9.9 APOA1 LPA
85 carpal tunnel syndrome 9.9 B2M TTR
86 aortic aneurysm, familial abdominal, 1 9.9
87 autoimmune disease 9.9
88 colchicine resistance 9.9
89 familial mediterranean fever, autosomal dominant 9.9
90 felty syndrome 9.9
91 periodic fever, familial, autosomal dominant 9.9
92 myositis 9.9
93 cyclic neutropenia 9.9
94 porphyria variegata 9.9
95 scleroderma, familial progressive 9.9
96 tracheopathia osteoplastica 9.9
97 lung cancer 9.9
98 celiac disease 1 9.9
99 lymphoma, hodgkin, classic 9.9
100 sjogren syndrome 9.9
101 glanzmann thrombasthenia 9.9
102 body mass index quantitative trait locus 11 9.9
103 caroli disease, isolated 9.9
104 body mass index quantitative trait locus 8 9.9
105 rheumatoid arthritis, systemic juvenile 9.9
106 psoriasis 7 9.9
107 gastrointestinal stromal tumor 9.9
108 body mass index quantitative trait locus 10 9.9
109 leukemia, chronic myeloid 9.9
110 body mass index quantitative trait locus 7 9.9
111 body mass index quantitative trait locus 14 9.9
112 psoriasis 11 9.9
113 cholangitis, primary sclerosing 9.9
114 psoriasis 13 9.9
115 infantile liver failure syndrome 1 9.9
116 body mass index quantitative trait locus 18 9.9
117 body mass index quantitative trait locus 19 9.9
118 acute liver failure 9.9
119 common variable immunodeficiency 9.9
120 crohn's disease 9.9
121 end stage renal failure 9.9
122 epidermolysis bullosa dystrophica 9.9
123 hepatitis 9.9
124 hepatitis b 9.9
125 leukemia 9.9
126 lymphedema 9.9
127 muscle disorders 9.9
128 neutropenia 9.9
129 ulcerative colitis 9.9
130 inflammatory bowel disease 9.9
131 small cell carcinoma 9.9
132 caroli disease 9.9
133 lymphoma 9.9
134 colitis 9.9
135 ischemic colitis 9.9
136 igg4-related disease 9.9
137 multicentric castleman disease 9.9
138 castleman disease 9.9
139 interstitial nephritis 9.9
140 spondyloarthropathy 9.9
141 autonomic neuropathy 9.9
142 nephrotic syndrome 9.9
143 crescentic glomerulonephritis 9.9
144 gout 9.9
145 porphyria 9.9
146 interstitial cystitis 9.9
147 sclerosing cholangitis 9.9
148 echinococcosis 9.9
149 nodular nonsuppurative panniculitis 9.9
150 panniculitis 9.9
151 cystitis 9.9
152 hidradenitis suppurativa 9.9
153 hidradenitis 9.9
154 corneal dystrophy 9.9
155 epidermolysis bullosa 9.9
156 membranoproliferative glomerulonephritis 9.9
157 churg-strauss syndrome 9.9
158 interstitial lung disease 9.9
159 aortic aneurysm 9.9
160 gastrointestinal tuberculosis 9.9
161 myopathy 9.9
162 schnitzler syndrome 9.9
163 human immunodeficiency virus infectious disease 9.9
164 lung disease 9.9
165 neuropathy 9.9
166 psoriasis 9.9
167 lattice corneal dystrophy 9.9
168 autosomal dominant polycystic kidney disease 9.9
169 leishmaniasis 9.9
170 visceral leishmaniasis 9.9
171 cholangitis 9.9
172 polycystic kidney disease 9.9
173 allergic angiitis 9.9
174 antisynthetase syndrome 9.9
175 eosinophilic granulomatosis with polyangiitis 9.9
176 medullary sponge kidney 9.9
177 microscopic polyangiitis 9.9
178 mycobacterium abscessus 9.9
179 rosai-dorfman disease 9.9
180 small cell carcinoma of the bladder 9.9
181 systemic onset juvenile idiopathic arthritis 9.9
182 thrombasthenia 9.9
183 hypobetalipoproteinemia, familial, 2 9.9 APOA1 LPA
184 obstructive jaundice 9.8 CRP TTR
185 hyperlipoproteinemia, type iii 9.8 APOA1 LPA
186 alzheimer disease 9.8
187 spinal cord injury 9.8
188 goiter 9.8
189 gastritis 9.8
190 achalasia 9.8
191 myelofibrosis 9.8
192 mycobacterium tuberculosis 1 9.8
193 sapho syndrome 9.8
194 erdheim-chester disease 9.8
195 lipogranulomatosis 9.8
196 prosthetic joint infection 9.8
197 carotid artery disease 9.7 APOA1 CRP LPA
198 peripheral vascular disease 9.7 APOA1 CRP LPA
199 vascular disease 9.7 APOA1 CRP LPA
200 arteries, anomalies of 9.7 APOA1 CRP LPA
201 atherosclerosis susceptibility 9.7 APOA1 CRP LPA
202 coronary artery anomaly 9.7 APOA1 CRP LPA
203 arteriosclerosis 9.7 APOA1 CRP LPA
204 osteomyelitis 9.7
205 poems syndrome 9.7
206 hypolipoproteinemia 9.7 APOA1 LCAT LPA
207 niemann-pick disease, type b 9.7 APOA1 LCAT LPA
208 arcus corneae 9.7 APOA1 LCAT LPA
209 multiple sclerosis 9.6
210 temporal arteritis 9.6
211 down syndrome 9.6
212 alkaptonuria 9.6
213 chediak-higashi syndrome 9.6
214 factor x deficiency 9.6
215 mycosis fungoides 9.6
216 basal cell carcinoma 1 9.6
217 headache associated with sexual activity 9.6
218 complement component 5 deficiency 9.6
219 malaria 9.6
220 aspergillosis 9.6
221 glycogen storage disease 9.6
222 joint disorders 9.6
223 multifocal motor neuropathy 9.6
224 systemic mastocytosis 9.6
225 systemic scleroderma 9.6
226 ileitis 9.6
227 recessive dystrophic epidermolysis bullosa 9.6
228 thrombosis 9.6
229 obstructive nephropathy 9.6
230 dermatomyositis 9.6
231 endocarditis 9.6
232 filariasis 9.6
233 lepromatous leprosy 9.6
234 sarcoma 9.6
235 pulmonary alveolar proteinosis 9.6
236 pyloric stenosis 9.6
237 blastomycosis 9.6
238 allergic bronchopulmonary aspergillosis 9.6
239 cholestasis 9.6
240 skeletal tuberculosis 9.6
241 calcinosis 9.6
242 hepatitis c 9.6
243 leiomyosarcoma 9.6
244 basal cell carcinoma 9.6
245 kidney cancer 9.6
246 periodontal disease 9.6
247 mixed connective tissue disease 9.6
248 mastocytosis 9.6
249 arthropathy 9.6
250 adrenal carcinoma 9.6
251 syphilis 9.6
252 ureteral obstruction 9.6
253 paraplegia 9.6
254 follicular dendritic cell sarcoma 9.6
255 progressive multifocal leukoencephalopathy 9.6
256 connective tissue disease 9.6
257 pellagra 9.6
258 hypopituitarism 9.6
259 bronchiectasis 9.6
260 hypereosinophilic syndrome 9.6
261 hypoaldosteronism 9.6
262 light chain deposition disease 9.6
263 pellucid marginal degeneration 9.6
264 pulmonary hyalinizing granuloma 9.6
265 discoid lupus erythematosus 9.6
266 lecithin:cholesterol acyltransferase deficiency 9.6 APOA1 LCAT LPA
267 tangier disease 9.6 APOA1 LCAT LPA
268 familial hyperlipidemia 9.6 APOA1 LCAT LPA
269 coronary heart disease 1 9.4 APOA1 CRP LCAT LPA
270 hypercholesterolemia, familial 9.4 APOA1 CRP LCAT LPA
271 diabetes mellitus, noninsulin-dependent 9.4 APOA1 CRP LCAT LPA
272 amyloidosis, familial visceral 8.7 APOA1 B2M LPA MEFV SAA1 SAA2

Graphical network of the top 20 diseases related to Amyloidosis Aa:



Diseases related to Amyloidosis Aa

Symptoms & Phenotypes for Amyloidosis Aa

Human phenotypes related to Amyloidosis Aa:

60 33 (showing 24, show less)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 hypotension 60 33 hallmark (90%) Very frequent (99-80%) HP:0002615
2 proteinuria 60 33 hallmark (90%) Very frequent (99-80%) HP:0000093
3 nephropathy 60 33 hallmark (90%) Very frequent (99-80%) HP:0000112
4 renal amyloidosis 60 33 hallmark (90%) Very frequent (99-80%) HP:0001917
5 hepatomegaly 60 33 frequent (33%) Frequent (79-30%) HP:0002240
6 malabsorption 60 33 frequent (33%) Frequent (79-30%) HP:0002024
7 vomiting 60 33 frequent (33%) Frequent (79-30%) HP:0002013
8 abdominal pain 60 33 frequent (33%) Frequent (79-30%) HP:0002027
9 venous thrombosis 60 33 frequent (33%) Frequent (79-30%) HP:0004936
10 nephrotic syndrome 60 33 frequent (33%) Frequent (79-30%) HP:0000100
11 cholestasis 60 33 frequent (33%) Frequent (79-30%) HP:0001396
12 chronic diarrhea 60 33 frequent (33%) Frequent (79-30%) HP:0002028
13 enlarged kidney 60 33 frequent (33%) Frequent (79-30%) HP:0000105
14 nausea 60 33 frequent (33%) Frequent (79-30%) HP:0002018
15 chronic kidney disease 60 33 frequent (33%) Frequent (79-30%) HP:0012622
16 malnutrition 60 33 frequent (33%) Frequent (79-30%) HP:0004395
17 abnormal oral mucosa morphology 33 frequent (33%) HP:0011830
18 acute kidney injury 60 33 occasional (7.5%) Occasional (29-5%) HP:0001919
19 hypothyroidism 60 33 very rare (1%) Very rare (<4-1%) HP:0000821
20 adrenal insufficiency 60 33 very rare (1%) Very rare (<4-1%) HP:0000846
21 abnormal heart morphology 60 33 very rare (1%) Very rare (<4-1%) HP:0001627
22 abnormality of the kidney 60 Very frequent (99-80%)
23 abnormality of oral mucosa 60 Frequent (79-30%)
24 amyloidosis 60 Very frequent (99-80%)

MGI Mouse Phenotypes related to Amyloidosis Aa:

47 (showing 1, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.23 APOA1 B2M CRP CTSB LCAT MEFV

Drugs & Therapeutics for Amyloidosis Aa

Drugs for Amyloidosis Aa (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 25, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Creatine Approved, Investigational, Nutraceutical Phase 3 57-00-1 586
2
Doxycycline Approved, Investigational, Vet_approved Phase 2 564-25-0 54671203
3 Daratumumab Approved Phase 2,Phase 1 945721-28-8
4
Mechlorethamine Approved, Investigational Phase 2 51-75-2 4033
5
Melphalan Approved Phase 2 148-82-3 460612 4053
6 Anti-Infective Agents Phase 2
7 Anti-Bacterial Agents Phase 2
8 Antiprotozoal Agents Phase 2
9 Antiparasitic Agents Phase 2
10 Antimalarials Phase 2
11 Immunologic Factors Phase 2,Phase 1
12 Antibodies, Monoclonal Phase 2,Phase 1
13 Antibodies Phase 2,Phase 1
14 Immunoglobulins Phase 2,Phase 1
15 alanine Phase 2
16 Alkylating Agents Phase 2
17 Immunosuppressive Agents Phase 2
18 phenylalanine Phase 2
19 Nitrogen Mustard Compounds Phase 2
20 Antineoplastic Agents, Alkylating Phase 2
21
Copper Approved, Investigational Phase 1 7440-50-8 27099
22 Nutrients Phase 1
23 Micronutrients Phase 1
24 Trace Elements Phase 1
25
Colchicine Approved 64-86-8 2833 6167

Interventional clinical trials:

(showing 8, show less)
# Name Status NCT ID Phase Drugs
1 Efficacy and Safety Study of KIACTA in Preventing Renal Function Decline in AA Amyloidosis Completed NCT01215747 Phase 3 KIACTA (eprodisate disodium);Placebo
2 Safety and Effect of Doxycycline in Patients With Amyloidosis Completed NCT01677286 Phase 2 Doxycycline 100 mg po bid x 12 months
3 Daratumumab After Stem Cell Transplant in Treating Patients With Multiple Myeloma Not yet recruiting NCT03346135 Phase 2 Melphalan
4 Copper 64Cu-DOTA-Daratumumab Positron Emission Tomography in Diagnosing Patients With Relapsed Multiple Myeloma Recruiting NCT03311828 Phase 1 Imaging Agent
5 Progression of Renal Amyloidosis of FMF and Relation to Serum SAA Level Unknown status NCT01168570
6 Recurrent AA Amyloidosis After Renal Transplantation Completed NCT02704065
7 Schnitzler Syndrome: Clinical Study, Physiopathological and Search for Genetic Factors Completed NCT00933296
8 Clinical Outcomes and Safety: A Registry Study of Ilaris (Canakinumab) Patients Completed NCT01213641

Search NIH Clinical Center for Amyloidosis Aa

Genetic Tests for Amyloidosis Aa

Genetic tests related to Amyloidosis Aa:

# Genetic test Affiliating Genes
1 Aa Amyloidosis 30

Anatomical Context for Amyloidosis Aa

MalaCards organs/tissues related to Amyloidosis Aa:

42
Kidney, Liver, Heart, Spleen, Lung, Bone, Skin

Publications for Amyloidosis Aa

Articles related to Amyloidosis Aa:

(showing 364, show less)
# Title Authors Year
1
Cell assay for the identification of amyloid inhibitors in systemic AA amyloidosis. ( 30739503 )
2019
2
Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids. ( 30846696 )
2019
3
Lipid membranes accelerate amyloid formation in the mouse model of AA amyloidosis. ( 30929476 )
2019
4
AA amyloidosis - Benefits and prospects of IL-6 inhibitors. ( 30132351 )
2019
5
Pulmonary Mycobacterium abscessus Infection with Reactive AA Amyloidosis: A Case Report and Brief Review of the Literature. ( 30333399 )
2019
6
Rheumatoid arthritis revealed by polyadenopathy, diarrhea and digestive AA amyloidosis. ( 30081199 )
2019
7
Systemic AA Amyloidosis Caused by Inflammatory Hepatocellular Adenoma. ( 30231230 )
2018
8
A rare cause of AA amyloidosis and end-stage kidney failure: Questions. ( 30456663 )
2018
9
A rare cause of AA amyloidosis and end-stage kidney failure: Answers. ( 30456664 )
2018
10
AA amyloidosis associated with morbid obesity (clinical case). ( 30527964 )
2018
11
Secondary, AA, Amyloidosis. ( 30274625 )
2018
12
Canakinumab treatment in kidney transplant recipients with AA amyloidosis due to familial Mediterranean fever. ( 29981275 )
2018
13
Recurrence of proteinuria after cessation of tocilizumab in patients with AA amyloidosis secondary to FMF. ( 30071938 )
2018
14
Apolipoprotein A-II induces acute-phase response associated AA amyloidosis in mice through conformational changes of plasma lipoprotein structure. ( 29618729 )
2018
15
Drawing attention to a neglected injecting-related harm: a systematic review of AA amyloidosis among people who inject drugs. ( 29697879 )
2018
16
'Care and Prevent': rationale for investigating skin and soft tissue infections and AA amyloidosis among people who inject drugs in London. ( 29739408 )
2018
17
Inhibitory effect of propolis on the development of AA amyloidosis. ( 29749997 )
2018
18
Successful treatment of systemic AA amyloidosis associated with underlying Hodgkin lymphoma. ( 29767440 )
2018
19
Profile of renal AA amyloidosis in older and younger individuals: a single-centre experience. ( 29775082 )
2018
20
Obesity is a significant susceptibility factor for idiopathic AA amyloidosis. ( 29364741 )
2018
21
Post mortem findings and their relation to AA amyloidosis in free-ranging Herring gulls (Larus argentatus). ( 29494674 )
2018
22
Diagnostic work up of an adult female patient with systemic AA amyloidosis revealing the cause of infantile mental retardation. ( 29166802 )
2018
23
Significant association between renal function and area of amyloid deposition in kidney biopsy specimens in both AA amyloidosis associated with rheumatoid arthritis and AL amyloidosis. ( 28613962 )
2017
24
Late ventricular potentials in familial Mediterranean fever with and without AA amyloidosis. ( 29164000 )
2017
25
Clinical outcomes and survival in AA amyloidosis patients. ( 29173691 )
2017
26
Safety and efficacy of empirical interleukin-1 inhibition using anakinra in AA amyloidosis of uncertain aetiology. ( 28745926 )
2017
27
Systemic AA amyloidosis in the red fox (Vulpes vulpes). ( 28791746 )
2017
28
Recurrent AA Amyloidosis Combined With Chronic Active Antibody-mediated Rejection After Kidney Transplantation. ( 28794296 )
2017
29
Spontaneous, Experimentally Induced, and Transmissible AA Amyloidosis in Japanese Quail ( Coturnix japonica). ( 28812532 )
2017
30
AA Amyloidosis and Atypical Familial Mediterranean Fever with Exon 2 and 3 Mutations. ( 28868300 )
2017
31
Seed-dependent templating of murine AA amyloidosis. ( 28434369 )
2017
32
Hepatic AA amyloidosis in a cat: cytologic and histologic identification of AA amyloid in macrophages. ( 28519899 )
2017
33
Gout and AA Amyloidosis: A Case Report and Review of the Literature. ( 28538281 )
2017
34
Tocilizumab in the treatment of twelve cases with aa amyloidosis secondary to familial mediterranean fever. ( 28558744 )
2017
35
AA amyloidosis associated with recurrent infections in the hyperimmunoglobulin E syndrome. ( 28571953 )
2017
36
Changing epidemiology of AA amyloidosis: clinical observations over 25 years at a single national referral centre. ( 28686088 )
2017
37
Kidney biopsy in AA amyloidosis: impact of histopathology on prognosis. ( 28686525 )
2017
38
Cell-to-cell transfer of SAA1 protein in a cell culture model of systemic AA amyloidosis. ( 28361953 )
2017
39
Isolated AA Amyloidosis of the Radial Nerve. ( 28391751 )
2017
40
Pleural effusion in AA amyloidosis - A rare involvement of a rare disease. ( 28427884 )
2017
41
Amyloid A (AA) amyloidosis in CByB6 mice: a model to study gastrointestinal amyloidosis. ( 28434288 )
2017
42
Prognostication of survival and progression to dialysis in AA amyloidosis. ( 28434292 )
2017
43
Apolipoprotein A-II accelerates reactive AA amyloidosis. ( 28434311 )
2017
44
Long-term tocilizumab efficacy in a patient with psoriatic arthritis and AA amyloidosis. ( 27908297 )
2017
45
Reply to: Long-term tocilizumab efficacy in a patient with psoriatic arthritis and AA amyloidosis. Dinoia et al. ( 27908298 )
2017
46
The M694I/M694I genotype: A genetic risk factor of AA-amyloidosis in a group of Algerian patients with familial Mediterranean fever. ( 27956278 )
2017
47
AA Amyloidosis and IgG4-Related Disease. ( 28177871 )
2017
48
AA amyloidosis is an emerging cause of nephropathy in obese patients. ( 28214252 )
2017
49
Identification of a Unique Amyloid Sequence in AA Amyloidosis of a Pig Associated With Streptococcus Suis Infection. ( 27520112 )
2017
50
Experimental transmission of systemic AA amyloidosis in autoimmune disease and type 2 diabetes mellitus model mice. ( 27321428 )
2016
51
Comparative Analysis of Outcomes of Kidney Transplantation in Patients With AA Amyloidosis and Chronic Glomerulonephritis. ( 27569937 )
2016
52
Poster 438 Bamboo Cervical Spine and Neck Pain in a Patient with AA Amyloidosis: A Case Report. ( 27673186 )
2016
53
Long-term follow-up on tocilizumab treatment of AA amyloidosis secondary to polyarteritis nodosa. ( 27791393 )
2016
54
Mutational Spectrum of the MEFV Gene in AA Amyloidosis Associated With Familial Mediterranean Fever. ( 27225717 )
2016
55
Is the presence of AA amyloidosis associated with impaired coronary flow reserve? ( 27282832 )
2016
56
Comparative evaluation of p5+14 with SAP and peptide p5 by dual-energy SPECT imaging of mice with AA amyloidosis. ( 26936002 )
2016
57
Detection of AA76, a Common Form of Amyloid A Protein, as a Way of Diagnosing AA Amyloidosis. ( 27098620 )
2016
58
Longitudinal study of experimental induction of AA amyloidosis in mice seeded with homologous and heterologous AA fibrils. ( 27165856 )
2016
59
Characteristics of AA amyloidosis patients in San Francisco. ( 26370715 )
2016
60
Severe hidradenitis suppurativa complicated by renal AA amyloidosis. ( 26206410 )
2016
61
Successful treatment with humanized anti-interleukin-6 receptor antibody (tocilizumab) in a case of AA amyloidosis complicated by familial Mediterranean fever. ( 25619282 )
2016
62
Effect of heating on the stability of amyloid A (AA) fibrils and the intra- and cross-species transmission of AA amyloidosis. ( 26588017 )
2015
63
Tocilizumab for AA Amyloidosis after Treatment of Multicentric Castleman Disease with Steroids, Chemotherapy and Rituximab for Over 20 Years. ( 26666616 )
2015
64
Therapeutic blockade of interleukin-6 by tocilizumab in the management of AA amyloidosis and chronic inflammatory disorders: a case series and review of the literature. ( 26120866 )
2015
65
Myopathy in a patient with systemic AA amyloidosis possibly induced by psoriasis vulgaris: An autopsy case. ( 26179325 )
2015
66
Unknown aspect of the old disease: does dyslipidemia in systemic AA amyloidosis differ from the dyslipidemia in primary glomerulonephritis? ( 26181645 )
2015
67
Safety of Percutaneous Ultrasound-Guided Kidney Biopsy in Patients with AA Amyloidosis. ( 26227420 )
2015
68
A case of membranoproliferative glomerulonephritis and AA amyloidosis complicated with pulmonary nontuberculous mycobacterial infection. ( 28509264 )
2015
69
Remission of nephrotic syndrome due to AA-amyloidosis, complicating familiar Mediterranean fever, with tocilizumab. ( 25572486 )
2015
70
AA amyloidosis treated with tocilizumab: case series and updated literature review. ( 25585627 )
2015
71
Predictors of AA amyloidosis in familial Mediterranean fever. ( 25586652 )
2015
72
Long-term kinetics of AA amyloidosis and effects of inflammatory restimulation after disappearance of amyloid depositions in mice. ( 25736960 )
2015
73
The Hidden Cost of Untreated Paragangliomas of the Head and Neck: Systemic Reactive (AA) Amyloidosis. ( 25838953 )
2015
74
Risk factors for AA amyloidosis in Germany. ( 25376380 )
2015
75
AA amyloidosis: pathogenesis and targeted therapy. ( 25387054 )
2015
76
Experimental transmission of AA amyloidosis by injecting the AA amyloid protein into interleukin-1 receptor antagonist knockout (IL-1raKO) mice. ( 25391376 )
2015
77
Protein profiling of isolated uterine AA amyloidosis causing fetal death in goats. ( 25422367 )
2015
78
Colchicine use in isolated renal AA amyloidosis. ( 25453598 )
2015
79
Tocilizumab in the treatment of patients with AA amyloidosis secondary to familial Mediterranean fever. ( 25504961 )
2015
80
Systemic AA amyloidosis as a prion-like disorder. ( 25533533 )
2015
81
Renal parenchymal calcification secondary to systemic AA amyloidosis. ( 25878784 )
2014
82
Renal AA Amyloidosis in Patients with Type 2 Diabetes Mellitus. ( 25337080 )
2014
83
Systemic AA amyloidosis: epidemiology, diagnosis, and management. ( 25378951 )
2014
84
Pearls from the Third Israeli Conference on FMF, other autoinflammatory disorders and AA amyloidosis. ( 24979827 )
2014
85
Cystic fibrosis and AA amyloidosis: a survey in the French cystic fibrosis network. ( 25054230 )
2014
86
Accumulation and absorption of serum amyloid A and apolipoprotein E fragments in the course of AA amyloidosis: a study in a mouse model. ( 25117094 )
2014
87
Therapeutic Benefits of Tocilizumab Vary in Different Organs of a Patient with AA Amyloidosis. ( 25197587 )
2014
88
Multidisciplinary approach to the treatment of cardiac AA amyloidosis and aortic stenosis due to Castleman's disease: a hybrid therapy with tocilizumab and aortic valve replacement. ( 24681024 )
2014
89
Renal cell carcinoma presenting as AA amyloidosis: a case report and review of the literature. ( 28509249 )
2014
90
AA amyloidosis-resistant CE/J mice have Saa1 and Saa2 genes that encode an identical SAA isoform. ( 24228751 )
2014
91
Study on the safety and efficacy of tocilizumab, an anti-IL-6 receptor antibody, in patients with rheumatoid arthritis complicated with AA amyloidosis. ( 24252016 )
2014
92
Comparison of the clinical utility of tocilizumab and anti-TNF therapy in AA amyloidosis complicating rheumatic diseases. ( 24261770 )
2014
93
Transmission of systemic AA amyloidosis in animals. ( 24280941 )
2014
94
AA amyloidosis as a complication of primary lymphedema. ( 23964754 )
2014
95
Nephrotic Syndrome Associated with Lung Cancer: A Rare Case of Malignancy Associated with AA Amyloidosis. ( 24558629 )
2013
96
Depletion of spleen macrophages delays AA amyloid development: a study performed in the rapid mouse model of AA amyloidosis. ( 24236094 )
2013
97
Decreasing incidence of AA amyloidosis in Spain. ( 24020894 )
2013
98
Decreasing incidence of AA amyloidosis in Spain. ( 24020924 )
2013
99
A case report of AA amyloidosis associated with familial periodic fever syndrome diagnosed after kidney transplantation: never say never. ( 24034047 )
2013
100
AA amyloidosis in a polyarteritis nodosa patient treated with tocilizumab. ( 24106820 )
2013
101
Variegate porphyria complicated by systemic AA amyloidosis: a case report. ( 24131077 )
2013
102
AA-amyloidosis in autosomal dominant polycystic kidney disease caused by chronic cyst infections lasting for 30 years. ( 23545677 )
2013
103
Experimental induction and oral transmission of avian AA amyloidosis in vaccinated white hens. ( 23548152 )
2013
104
Renal involvement in AA amyloidosis: clinical outcomes and survival. ( 23548761 )
2013
105
AA amyloidosis in vaccinated growing chickens. ( 23570943 )
2013
106
Transmission of AA amyloidosis may cause outbreaks of amyloid A amyloidosis in chickens. ( 23642208 )
2013
107
Nephrotic syndrome and AA amyloidosis revealing adult-onset cryopyrin-associated periodic syndrome. ( 23650909 )
2013
108
AA amyloidosis associated with systemic-onset juvenile idiopathic arthritis. ( 23664546 )
2013
109
Decreasing incidence of AA amyloidosis in Spain. ( 23683125 )
2013
110
AA amyloidosis complicating the hereditary periodic fever syndromes. ( 23280696 )
2013
111
Inflammatory bowel disease and systemic AA amyloidosis. ( 23371008 )
2013
112
Control of AA amyloidosis complicating Crohn's disease: a clinico-pathological study. ( 23373823 )
2013
113
Systemic AA amyloidosis as a unique manifestation of a combined mutation of TNFRSF1A and MEFV genes. ( 23461592 )
2013
114
When first line therapy for AA-amyloidosis secondary to rheumatoid arthritis fails: a correspondence. ( 23022420 )
2013
115
Gastrointestinal AA amyloidosis following allogeneic hematopoietic stem cell transplant in a patient with chronic myelogenous leukemia. ( 23163702 )
2013
116
Successful treatment of protein-losing enteropathy due to AA amyloidosis with octreotide in a patient with rheumatoid arthritis. ( 22815005 )
2013
117
[Renal AA amyloidosis during Langerhans' cell histiocytosis: case report]. ( 24282006 )
2013
118
Systemic AA amyloidosis. ( 23225016 )
2012
119
AA amyloidosis: Mount Sinai experience, 1997-2012. ( 23239212 )
2012
120
Massive pleural effusion due to pleural AA amyloidosis. ( 23250505 )
2012
121
Effects of AA amyloidosis on survival in peritoneal dialysis. ( 23147073 )
2012
122
Renal AA-amyloidosis in intravenous drug users--a role for HIV-infection? ( 23171281 )
2012
123
AA Amyloidosis in a patient with glycogen storage disorder and progressive chronic kidney disease. ( 26069801 )
2012
124
Unusual renal manifestation of Caroli disease: AA amyloidosis. ( 22681158 )
2012
125
Concurrent systemic AA amyloidosis can discriminate primary sclerosing cholangitis from IgG4-associated cholangitis. ( 22253527 )
2012
126
Churg-Strauss syndrome associated with AA amyloidosis: a case report. ( 22891088 )
2012
127
AA-amyloidosis in a kidney biopsy on top of pauci-immune crescentic glomerulonephritis. ( 26069756 )
2012
128
A case of AA amyloidosis of the bladder with interstitial cystitis. ( 22905727 )
2012
129
Remission of proteinuria and preservation of renal function in patients with renal AA amyloidosis secondary to rheumatoid arthritis. ( 21771754 )
2012
130
Atypical AA amyloid deposits in bovine AA amyloidosis. ( 22149364 )
2012
131
Tocilizumab improves cardiac disease in a hemodialysis patient with AA amyloidosis secondary to rheumatoid arthritis. ( 22260742 )
2012
132
The relation between urinary angiotensinogen and proteinuria in renal AA amyloidosis patients. ( 22320202 )
2012
133
Review of eprodisate for the treatment of renal disease in AA amyloidosis. ( 22427728 )
2012
134
Idiopathic systemic AA-amyloidosis in a skunk (Mephitis mephitis). ( 22448530 )
2012
135
AA amyloidosis: basic knowledge, unmet needs and future treatments. ( 22653707 )
2012
136
AA amyloidosis in the renal allograft: a report of two cases and review of the literature. ( 22833808 )
2012
137
Systemic AA amyloidosis in a patient with lung metastasis from renal cell carcinoma. ( 22928906 )
2012
138
Renal AA amyloidosis in a Castleman's disease patient. ( 23013971 )
2012
139
Antisynthetase syndrome without myositis secondary to AA amyloidosis: a non-described association. ( 21270928 )
2011
140
Systemic reactive (AA) amyloidosis in the course of common variable immunodeficiency. ( 21838492 )
2011
141
P-wave dispersion in systemic AA amyloidosis of familial Mediterranean fever. ( 21484223 )
2011
142
Abnormal heart rate variability in AA amyloidosis of familial Mediterranean fever. ( 22080764 )
2011
143
Successful treatment of renal AA amyloidosis in familial Mediterranean fever with pegylated alpha-2a interferon. ( 21269584 )
2011
144
AA amyloidosis in a patient with Langerhans cell histiocytosis. ( 25984125 )
2011
145
Successful use of tocilizumab in a patient with nephrotic syndrome due to a rapidly progressing AA amyloidosis secondary to latent tuberculosis. ( 21992511 )
2011
146
Colchicine-sensitive nephrotic syndrome due to AA amyloidosis. ( 21770831 )
2011
147
Fatal acute pancreatitis associated with reactive AA amyloidosis in rheumatoid arthritis with end-stage renal disease: a report of three cases. ( 21467708 )
2011
148
A case with rheumatoid arthritis and systemic reactive AA amyloidosis showing rapid regression of amyloid deposition on gastroduodenal mucosa after a combined therapy of corticosteroid and etanercept. ( 19820941 )
2011
149
Rituximab therapy for AA-amyloidosis secondary to rheumatoid arthritis. ( 21067952 )
2011
150
Favourable and sustained response to anakinra in tumour necrosis factor receptor-associated periodic syndrome (TRAPS) with or without AA amyloidosis. ( 21173015 )
2011
151
Recent insights into the pathogenesis of type AA amyloidosis. ( 21403980 )
2011
152
Recurrent AA amyloidosis in a kidney transplant. ( 21496981 )
2011
153
AA amyloidosis associated with hepatitis B. ( 21543651 )
2011
154
Cardiac AA amyloidosis in a patient with rheumatoid arthritis and systemic sclerosis: the therapeutic potential of biological reagents. ( 21639824 )
2011
155
Renal transplantation in patients with AA amyloidosis nephropathy: results from a French multicenter study. ( 21714848 )
2011
156
Antisense oligonucleotide suppression of serum amyloid A reduces amyloid deposition in mice with AA amyloidosis. ( 21830877 )
2011
157
Inhibitory effects of anti-IL-1β antibody in murine AA amyloidosis mode. ( 21838425 )
2011
158
AA amyloidosis: potential therapy with antisense oligonucleotides. ( 21838487 )
2011
159
The changing face of AA amyloidosis: a single center experience. ( 21838497 )
2011
160
Renal AA amyloidosis in a patient with hereditary complete complement C4 deficiency. ( 21912034 )
2011
161
Renal transplantation in AA amyloidosis associated with Whipple's disease. ( 21995309 )
2011
162
Echocardiographic diagnosis of systemic AA amyloidosis presenting with acute liver failure. ( 20821940 )
2010
163
Anakinra efficacy in a Caucasian patient with renal AA amyloidosis secondary to cryopyrin-associated periodic syndrome. ( 20609610 )
2010
164
AA amyloidosis associated with macroglobulinemia. ( 20953745 )
2010
165
Coexistence of medullary sponge kidney and renal AA amyloidosis in a patient with nephrotic range proteinuria. ( 20355355 )
2010
166
Oral involvement in a case of AA amyloidosis: a case report. ( 20591157 )
2010
167
Spontaneous resolution of multiple nodular pulmonary AA amyloidosis. ( 21048364 )
2010
168
AA-amyloidosis caused by visceral leishmaniasis in a human immunodeficiency virus-infected patient. ( 19635871 )
2009
169
Unusual combination of tracheobronchopathia osteochondroplastica and AA amyloidosis. ( 19881980 )
2009
170
Renal AA amyloidosis secondary to morbid obesity? ( 19825338 )
2009
171
Susceptibility to AA amyloidosis in rheumatic diseases: a critical overview. ( 19790131 )
2009
172
Oto-Rhino-Laryngology (ORL) tumor presentation in a case of systemic AA amyloidosis. ( 19951642 )
2009
173
Renal AA amyloidosis: survey of epidemiologic and laboratory data from one nephrology centre. ( 19184513 )
2009
174
AA amyloidosis induced in sheep principally affects the gastrointestinal tract. ( 19217631 )
2009
175
Unexpected remission of renal AA amyloidosis associated with rheumatoid arthritis. ( 19303340 )
2009
176
Long-term efficacy of infliximab treatment for AA-amyloidosis secondary to chronic inflammatory arthritis. ( 19366896 )
2009
177
Rapid improvement of AA amyloidosis with humanised anti-interleukin 6 receptor antibody treatment. ( 19525413 )
2009
178
Fibrils from designed non-amyloid-related synthetic peptides induce AA-amyloidosis during inflammation in an animal model. ( 19582162 )
2009
179
Increasing fatal AA amyloidosis in hunting falcons and how to identify the risk: a report from the United Arab Emirates. ( 19657764 )
2009
180
AA amyloidosis associated with a mutated serum amyloid A4 protein. ( 20536400 )
2009
181
An autopsy case of multicentric Castleman's disease associated with interstitial nephritis and secondary AA amyloidosis. ( 18224416 )
2008
182
Another devastating complication of the Schnitzler syndrome: AA amyloidosis. ( 17941941 )
2008
183
Secondary cutaneous nodular AA amyloidosis in a patient with primary Sjögren syndrome and celiac disease. ( 18431095 )
2008
184
AA amyloidosis associated with systemic lupus erythematosus: impact on clinical course and outcome. ( 17687556 )
2008
185
Rapid induction of experimental AA amyloidosis in mink by intravenous injection of amyloid enhancing factor. ( 18266118 )
2008
186
Spontaneous perirenal hematoma with AA amyloidosis in a hemodialysis patient after unilateral nephrectomy. ( 18266124 )
2008
187
Effect of etanercept on serum amyloid A protein (SAA) levels in patients with AA amyloidosis complicating inflammatory arthritis. ( 18379834 )
2008
188
Fecal transmission of AA amyloidosis in the cheetah contributes to high incidence of disease. ( 18474855 )
2008
189
A case of AA amyloidosis associated with rheumatoid arthritis effectively treated with Infliximab. ( 18496698 )
2008
190
AA amyloidosis due to chronic oxalate arthritis and vasculitis in a patient with secondary oxalosis after jejunoileal bypass surgery. ( 18632590 )
2008
191
Increased susceptibility of serum amyloid A 1.1 to degradation by MMP-1: potential explanation for higher risk of type AA amyloidosis. ( 18815155 )
2008
192
AA-amyloidosis can be transferred by peripheral blood monocytes. ( 18830411 )
2008
193
Quantitative tomography of early-onset spontaneous AA amyloidosis in interleukin 6 transgenic mice. ( 19149411 )
2008
194
[AA amyloidosis: a little-known complication of chronic leg ulcer]. ( 18342093 )
2008
195
Systemic reactive (AA) amyloidosis in a patient with Glanzmann thrombasthenia. ( 17968693 )
2007
196
Analysis of SAA1 gene polymorphisms in the Greek population: rheumatoid arthritis and FMF patients relative to normal controls. Homogeneous distribution and low incidence of AA amyloidosis. ( 17968686 )
2007
197
Localized Castleman's disease associated with systemic AA amyloidosis. Regression of amyloid deposits after tumor removal. ( 17001479 )
2007
198
Rheumatoid arthritis-induced pseudotumoral AA amyloidosis of the bladder with vesico-peritoneal fistula. ( 17269598 )
2007
199
Eprodisate for the treatment of renal disease in AA amyloidosis. ( 17554116 )
2007
200
Natural history and outcome in systemic AA amyloidosis. ( 17554117 )
2007
201
Inactivation of amyloid-enhancing factor (AEF): study on experimental murine AA amyloidosis. ( 17572844 )
2007
202
Diagnostic performance of amyloid A protein quantification in fat tissue of patients with clinical AA amyloidosis. ( 17577686 )
2007
203
Experimental AA amyloidosis in mice is inhibited by treatment with triptolide, a purified traditional Chinese medicine. ( 17630202 )
2007
204
Quiz page. Renal AA amyloidosis with vascular predominance, secondary to rheumatoid arthritis. ( 17687809 )
2007
205
Clinical and histological characteristics of renal AA amyloidosis: a retrospective study of 68 cases with a special interest to amyloid-associated inflammatory response. ( 17714761 )
2007
206
Eprodisate in AA amyloidosis. ( 17855678 )
2007
207
Eprodisate slows the progression of renal disease in patients with AA amyloidosis. ( 17876351 )
2007
208
Efficacy of etanercept in patients with AA amyloidosis secondary to rheumatoid arthritis. ( 17888205 )
2007
209
Induction of murine AA amyloidosis by various homogeneous amyloid fibrils and amyloid-like synthetic peptides. ( 17953525 )
2007
210
Systemic AA-amyloidosis related to MPO-ANCA microscopic polyangiitis: a case report. ( 17062385 )
2006
211
AA amyloidosis in psoriatic arthritis. ( 16872037 )
2006
212
Renal AA amyloidosis in a dairy cow in Turkey. ( 16581997 )
2006
213
Synchronous carcinomas of stomach and bladder together with AA amyloidosis. ( 16669973 )
2006
214
AA amyloidosis complicating hyperimmunoglobulinemia D with periodic fever syndrome: a report of two cases. ( 16732551 )
2006
215
Two distinct clinical courses of renal involvement in rheumatoid patients with AA amyloidosis. ( 16881107 )
2006
216
Immunohistochemical distribution of amyloid deposits in 25 cows diagnosed with systemic AA amyloidosis. ( 16891786 )
2006
217
FK506 inhibits murine AA amyloidosis: possible involvement of T cells in amyloidogenesis. ( 16981291 )
2006
218
SAA1 gene polymorphisms and the risk of AA amyloidosis in Japanese patients with rheumatoid arthritis. ( 17039310 )
2006
219
Histopathological regression of systemic AA amyloidosis after surgical treatment of a localized Castleman's disease. ( 17062386 )
2006
220
HLA-DRB1*04 alleles in Japanese rheumatoid arthritis patients with AA amyloidosis. ( 17086601 )
2006
221
Immunosuppressive treatment of AA amyloidosis of familial Mediterranean fever. ( 16273776 )
2005
222
Severe protein losing enteropathy with intractable diarrhea due to systemic AA amyloidosis, successfully treated with corticosteroid and octreotide. ( 16076611 )
2005
223
Autosomal dominant periodic fever with AA amyloidosis: tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in a Turkish family. ( 16299693 )
2005
224
Systemic AA amyloidosis in the common marmoset. ( 15753464 )
2005
225
Systemic AA-amyloidosis in a European wild boar (Sus scrofa) suffering from generalized tuberculosis. ( 15836445 )
2005
226
Localised plasma-cell type Castleman's disease and AA-amyloidosis cured by resection. A case report and review of the literature. ( 15981701 )
2005
227
Unexpectedly high incidence of visceral AA-amyloidosis in slaughtered cattle in Japan. ( 16011986 )
2005
228
Tissue Doppler is a more reliable method in early detection of cardiac dysfunction in patients with AA amyloidosis. ( 16060129 )
2005
229
Renal medullary AA amyloidosis, hepatocyte dissociation and multinucleated hepatocytes in a 14-year-old free-ranging lioness (Panthera leo). ( 16108528 )
2005
230
AA amyloidosis and pyrin gene mutations. ( 16119533 )
2005
231
Quantitative high-resolution microradiographic imaging of amyloid deposits in a novel murine model of AA amyloidosis. ( 16194869 )
2005
232
A severe autosomal-dominant periodic inflammatory disorder with renal AA amyloidosis and colchicine resistance associated to the MEFV H478Y variant in a Spanish kindred: an unusual familial Mediterranean fever phenotype or another MEFV-associated periodic inflammatory disorder? ( 14679589 )
2004
233
Infliximab treatment of Familial Mediterranean fever and its effect on secondary AA amyloidosis. ( 17043487 )
2004
234
Case report: Response in proteinuria due to AA amyloidosis but not Felty's syndrome in a patient with rheumatoid arthritis treated with TNF-alpha blockade. ( 15103032 )
2004
235
Humoral proinflammatory cytokine and SAA generation profiles and spatio-temporal relationship between SAA and lysosomal cathepsin B and D in murine splenic monocytoid cells during AA amyloidosis. ( 14871293 )
2004
236
Allelic variants in genes associated with hereditary periodic fever syndromes as susceptibility factors for reactive systemic AA amyloidosis. ( 15071491 )
2004
237
An unusual case of recurrence of AA amyloidosis in the renal allograft. ( 15083929 )
2004
238
Anti-interleukin 6 receptor antibody inhibits murine AA-amyloidosis. ( 15170926 )
2004
239
Anaemia of chronic disease in AA amyloidosis is associated with allele 2 of the interleukin-1beta-511 promoter gene and raised levels of interleukin-1beta and interleukin-18. ( 15257727 )
2004
240
First report of systemic reactive (AA) amyloidosis in a patient with the hyperimmunoglobulinemia D with periodic fever syndrome. ( 15457465 )
2004
241
Serum amyloid A protein forms a complex with a fragment of apolipoprotein A-I in the domestic blue fox: a protective mechanism against AA amyloidosis? ( 15523921 )
2004
242
Kinetics of glycosaminoglycan deposition in splenic AA amyloidosis induced in mink. ( 15584971 )
2004
243
Familial Mediterranean fever (FMF) and renal AA amyloidosis--phenotype-genotype correlation, treatment and prognosis. ( 12832747 )
2003
244
Systemic AA amyloidosis and nephrotic syndrome associated with small cell carcinoma of the bladder. ( 14551390 )
2003
245
Cytostatic therapy for AA amyloidosis complicating psoriatic spondyloarthropathy. ( 12595637 )
2003
246
Pathology of AA amyloidosis in domestic sheep and goats. ( 12627715 )
2003
247
Advanced glycation end products and receptor for advanced glycation end products in AA amyloidosis. ( 12651613 )
2003
248
Spontaneous pneumoperitoneum: an unusual complication of systemic reactive AA amyloidosis secondary to rheumatoid arthritis. ( 12762142 )
2003
249
Phenol Congo red staining enhances the diagnostic value of abdominal fat aspiration biopsy in reactive AA amyloidosis secondary to rheumatoid arthritis. ( 12793709 )
2003
250
Clinical outcome and survival of secondary (AA) amyloidosis. ( 12846054 )
2003
251
Anti-tumor necrosis factor alpha therapy in fifteen patients with AA amyloidosis secondary to inflammatory arthritides: a followup report of tolerability and efficacy. ( 12847696 )
2003
252
Clinicopathological features in ovine AA amyloidosis. ( 13129668 )
2003
253
Abdominal fat aspiration biopsy and genotyping of serum amyloid A contribute to early diagnosis of reactive AA amyloidosis secondary to rheumatoid arthritis. ( 14518665 )
2003
254
Fatal acute pancreatitis with cystic formation in reactive systemic AA amyloidosis secondary to rheumatoid arthritis. ( 14518683 )
2003
255
Histological study of experimental murine AA amyloidosis. ( 14599103 )
2003
256
Resolution with etanercept of nephrotic syndrome due to renal AA amyloidosis in adult Still's disease. ( 14599647 )
2003
257
Oral involvement in a case of AA amyloidosis. ( 14628895 )
2003
258
Heme-oxygenase-1 response, a marker of oxidative stress, in a mouse model of AA amyloidosis. ( 14640029 )
2003
259
Efficacy of cyclophosphamide combined with prednisolone in patients with AA amyloidosis secondary to rheumatoid arthritis. ( 14677008 )
2003
260
Left atrial myxoma associated with systemic AA amyloidosis. ( 14690267 )
2003
261
Possible relationship between AA amyloidosis and decreased complements in patients with rheumatoid arthritis. ( 17041475 )
2003
262
AA amyloidosis complicating an inflammatory abdominal aortic aneurysm. ( 11812880 )
2002
263
Remission of nephrotic syndrome due to AA amyloidosis and initiation of glomerular repair after surgical resection of localized Castleman's disease. ( 11867955 )
2002
264
Quiz page. AA amyloidosis. ( 11881640 )
2002
265
Unicentric Castleman's disease complicated by systemic AA amyloidosis: a curable disease. ( 11937647 )
2002
266
Acceleration of murine AA amyloidosis by oral administration of amyloid fibrils extracted from different species. ( 11940205 )
2002
267
Pathology, diagnosis and pathogenesis of AA amyloidosis. ( 11964039 )
2002
268
Ambulatory treatment with intravenous norepinephrine in a patient with end stage renal disease and generalized AA amyloidosis. ( 12000198 )
2002
269
Long-term follow-up of systemic reactive AA amyloidosis secondary to rheumatoid arthritis: successful treatment with intermediate-dose corticosteroid. ( 12058893 )
2002
270
Mutational spectrum in the MEFV and TNFRSF1A genes in patients suffering from AA amyloidosis and recurrent inflammatory attacks. ( 12105243 )
2002
271
Treatment of AA amyloidosis in rheumatoid arthritis. ( 12126345 )
2002
272
Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. ( 12355493 )
2002
273
Raised circulating interleukin-18 levels in reactive AA-amyloidosis. ( 12440487 )
2002
274
Waldenström's macroglobulinemia associated with AA amyloidosis. ( 11530809 )
2001
275
Renal failure and nephrotic syndrome associated with gastrointestinal stromal tumour (GIST)-a rare cause of AA amyloidosis. ( 11427662 )
2001
276
Autosomal-dominant periodic fever with AA amyloidosis: Novel mutation in tumor necrosis factor receptor 1 gene Rapid Communication. ( 11318938 )
2001
277
A novel single-nucleotide polymorphism at the 5'-flanking region of SAA1 associated with risk of type AA amyloidosis secondary to rheumatoid arthritis. ( 11407685 )
2001
278
Genotypes at SAA1 locus correlate with the clinical severity of AA-amyloidosis. ( 11409033 )
2001
279
Amyloid proteins in pathogenesis of AA amyloidosis. ( 11454365 )
2001
280
Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid A protein. ( 11454373 )
2001
281
Renal type AA amyloidosis associated with rheumatoid arthritis: a cohort study showing improved survival on treatment with pulse cyclophosphamide. ( 11477289 )
2001
282
Necrotizing angiitis of the small intestine related to AA-amyloidosis: a novel association. ( 11484503 )
2001
283
Spontaneous abdominal hemorrhage with AA-amyloidosis and vasculitis in a patient with rheumatoid arthritis. ( 17039102 )
2001
284
Cyclic neutropenia complicated by renal AA amyloidosis. ( 10731873 )
2000
285
Successful treatment of protein-losing enteropathy due to AA amyloidosis with somatostatin analogue and high dose steroid in ankylosing spondylitis. ( 11072606 )
2000
286
Rosai-Dorfman disease and generalized AA amyloidosis: a case report. ( 10836304 )
2000
287
Extensive haemorrhagic-bullous skin manifestation of systemic AA-amyloidosis associated with IgGlambda-myeloma. ( 10694315 )
2000
288
Presentation, survival and prognostic markers in AA amyloidosis. ( 10924536 )
2000
289
An autosomal dominant periodic fever associated with AA amyloidosis in a north Indian family maps to distal chromosome 1q. ( 11014353 )
2000
290
Giant cell arteritis "causing" AA-amyloidosis with rapid renal failure. ( 11100514 )
2000
291
Generalized AA-amyloidosis in a 58-year-old Caucasian woman with an 18-month history of gastrointestinal tuberculosis. ( 10071242 )
1999
292
Transgenic mouse model of AA amyloidosis. ( 10233864 )
1999
293
Reversal of nephrotic syndrome due to AA amyloidosis in psoriatic patients on long-term colchicine treatment. Case report and review of the literature. ( 10450037 )
1999
294
AA amyloidosis in Takayasu's arteritis--long-term survival on maintenance haemodialysis. ( 10528678 )
1999
295
Influence of genotypes at SAA1 and SAA2 loci on the development and the length of latent period of secondary AA-amyloidosis in patients with rheumatoid arthritis. ( 10543406 )
1999
296
Successful treatment of AA amyloidosis secondary to Hodgkin's disease with 4'-iodo-4'-deoxydoxorubicin. ( 10091401 )
1999
297
[Serum amyloid A (SAA) 1, SAA 2 and apolipoprotein E isotype frequencies in rheumatoid arthritis patients with AA amyloidosis]. ( 10332210 )
1999
298
Generalized AA-amyloidosis in Siberian tigers (Panthera tigris altaica) with predominant renal medullary amyloid deposition. ( 9545138 )
1998
299
Renal AA amyloidosis--a long-term sequela of jejuno-ileal bypass. ( 9681744 )
1998
300
AA amyloidosis in systemic lupus erythematosus: an unusual complication. ( 9681745 )
1998
301
Clinical benefits of diagnosing incipient AA amyloidosis in pediatric rheumatic diseases as estimated from a retrospective study. ( 9818057 )
1998
302
SAA1 alleles as risk factors in reactive systemic AA amyloidosis. ( 10036584 )
1998
303
Generalized AA-amyloidosis in Siamese and Oriental cats. ( 9220576 )
1997
304
Vascular renal AA amyloidosis in adult Still's disease. ( 9269657 )
1997
305
Systemic AA amyloidosis in captive cheetahs (Acinonyx jubatus). ( 9396135 )
1997
306
Electrocardiography and Doppler echocardiography in secondary (AA) amyloidosis. ( 8607418 )
1996
307
Experimental AA-amyloidosis in mice is inhibited by treatment with the anti-rheumatic drug tenidap. ( 8633214 )
1996
308
Inflammatory syndrome of footpads in puppies and AA-amyloidosis. ( 8734514 )
1996
309
Generalised AA-amyloidosis in a bat (Pipistrellus pipistrellus). ( 8817841 )
1996
310
Brefeldin A inhibits experimentally induced AA amyloidosis. ( 8838515 )
1996
311
Fatal systemic amyloidosis (AA type) in two sisters with dystrophic epidermolysis bullosa. ( 7615888 )
1995
312
Systemic AA amyloidosis induced by oral contraceptive-associated hepatocellular adenoma: a 13-year follow up. ( 7674844 )
1995
313
High-sensitivity diagnosis of AA amyloidosis using Congo red and immunohistochemistry detects missed amyloid deposits. ( 7642960 )
1995
314
A novel allelic variant of serum amyloid A, SAA1 gamma: genomic evidence, evolution, frequency, and implication as a risk factor for reactive systemic AA-amyloidosis. ( 7655463 )
1995
315
Reversal of nephrotic syndrome due to reactive amyloidosis (AA-type) after excision of localized Castleman's disease. ( 7910717 )
1994
316
Idiopathic AA amyloidosis manifested by autonomic neuropathy, vestibulocochleopathy, and lattice corneal dystrophy. ( 8201343 )
1994
317
Colchicine treatment of AA amyloidosis of familial Mediterranean fever. An analysis of factors affecting outcome. ( 7986228 )
1994
318
AA-amyloidosis presenting with chronic diarrhea and cardiac manifestations. ( 7830334 )
1994
319
The epidemiology of AL and AA amyloidosis. ( 7954866 )
1994
320
Clinical and therapeutic aspects of AA amyloidosis. ( 7954868 )
1994
321
Characterization of proteoglycans associated with mouse splenic AA amyloidosis. ( 7980430 )
1994
322
Fibrils from synthetic amyloid-related peptides enhance development of experimental AA-amyloidosis in mice. ( 8123028 )
1994
323
AA amyloidosis and AL amyloidosis. ( 8204969 )
1993
324
Pulmonary nodules due to reactive systemic amyloidosis (AA) in Crohn's disease. ( 8303644 )
1993
325
Ischemic colitis complicating AA amyloidosis and familial Mediterranean fever. ( 8491572 )
1993
326
Serum amyloid P component scintigraphy and turnover studies for diagnosis and quantitative monitoring of AA amyloidosis in juvenile rheumatoid arthritis. ( 8507227 )
1993
327
Results, principles and pitfalls in the management of renal AA-amyloidosis; a 10-21 year followup of 16 patients with rheumatic disease treated with alkylating cytostatics. ( 8014932 )
1993
328
Secondary (AA) amyloidosis associated with Castleman's disease. Report of two cases and review of the literature. ( 8213634 )
1993
329
Gastrointestinal AAPOAII and systemic AA-amyloidosis in aged C57BL/Ka mice. Amyloid-type dependent effect of long-term immunosuppressive treatment. ( 8401815 )
1993
330
Remission of nephrotic syndrome related to AA amyloidosis after hepatic adenomectomy. ( 8502327 )
1993
331
Secondary amyloidosis (AA). ( 1474356 )
1992
332
Diffuse interstitial lung disease due to AA amyloidosis. ( 1585301 )
1992
333
Renal AA amyloidosis in a patient with Bence Jones proteinuria and ankylosing spondylitis. ( 1430270 )
1992
334
Identification of two novel amyloid A protein subsets coexisting in an individual patient of AA-amyloidosis. ( 1463770 )
1992
335
Studies in vivo and in vitro of serum amyloid P component in normals and in a patient with AA amyloidosis. ( 1673879 )
1991
336
Endocrine organ failure due to systemic AA-amyloidosis. ( 2030805 )
1991
337
Amyloidosis (AA type) with gastrointestinal involvement: resolution of gastric amyloid deposition in parallel with disappearance of the serum component of amyloid A protein. ( 2232367 )
1990
338
Systemic AA amyloidosis induced by liver cell adenoma. ( 2157638 )
1990
339
A noninvasive screening of systemic reactive (secondary) AA amyloidosis, based on reduced amyloid degrading activity of amyloidotic serum. ( 2347684 )
1990
340
AA-amyloidosis. Tissue component-specific association of various protein AA subspecies and evidence of a fourth SAA gene product. ( 2386201 )
1990
341
Massive vascular AA-amyloidosis: a histologically and biochemically distinctive subtype of reactive systemic amyloidosis. ( 2587936 )
1989
342
Amino acid sequence variations in protein AA of cats with high and low incidences of AA amyloidosis. ( 2605915 )
1989
343
Histomorphological variations in systemic AA amyloidosis: clues of AA protein polymorphism. ( 2707747 )
1989
344
Left atrial myxoma associated with systemic AA amyloidosis. ( 2916891 )
1989
345
Resolution of amyloidosis (AA type) complicating chronic ulcerative colitis. ( 3396825 )
1988
346
Morphologic differences in the pattern of liver infiltration between systemic AL and AA amyloidosis. ( 2454214 )
1988
347
Generalized AA-amyloidosis in two hares (Lepus europaeus) immunohistochemically identified using poly- and monoclonal antibodies. ( 3068895 )
1988
348
Hepatic AA amyloidosis associated with severe strongylosis in a horse. ( 3168987 )
1988
349
AA amyloidosis associated with systemic lupus erythematosus. ( 3175452 )
1988
350
A reproducible model for the study of factor X kinetics in AA amyloidosis. ( 3371463 )
1988
351
Characterization of tissue and plasma glycosaminoglycans during experimental AA amyloidosis and acute inflammation. Qualitative and quantitative analysis. ( 3599910 )
1987
352
A new model of AA-amyloidosis induced by oral pristane in BALB/c mice. ( 3620333 )
1987
353
AA amyloidosis in systemic lupus erythematosus. ( 3668991 )
1987
354
Amyloid-enhancing factor (AEF) in the pathogenesis of AA-amyloidosis in the hamster. ( 2879382 )
1986
355
Immunohistochemical identification of generalized AA-amyloidosis in a mountain gazelle (Gazella gazella). ( 3511600 )
1986
356
Secondary (AA) amyloidosis in cystic fibrosis. A report of three cases. ( 3953498 )
1986
357
Activities of lysosomal enzymes and levels of serum amyloid A (SAA) in blood plasma of hamsters during casein induction of AA-amyloidosis. ( 2860918 )
1985
358
Is amyloid A (AA) amyloidosis always secondary? ( 3985695 )
1985
359
AA-amyloidosis in dogs: partial amino acid sequence of protein AA and immunohistochemical cross-reactivity with human and cow AA-amyloid. ( 4053581 )
1985
360
Pathogenesis of AA amyloidosis. ( 6731042 )
1984
361
Amyloidosis (AA type) associated with nodular nonsuppurative panniculitis. ( 6625383 )
1983
362
Murine alveolar hydatidosis: a potential experimental model for the study of AA-amyloidosis. ( 6661394 )
1983
363
Dimethyl sulfoxide in the treatment of AA amyloidosis. ( 6410966 )
1983
364
Protein AA amyloidosis in Nigeria. ( 7176004 )
1982

Variations for Amyloidosis Aa

Expression for Amyloidosis Aa

Search GEO for disease gene expression data for Amyloidosis Aa.

Pathways for Amyloidosis Aa

Pathways related to Amyloidosis Aa according to GeneCards Suite gene sharing:

(showing 3, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.36 APOA1 CRP SAA1 SAA2 SAA4
2
Show member pathways
11.2 APOA1 LCAT LPA
3 10.8 APOA1 TTR

GO Terms for Amyloidosis Aa

Cellular components related to Amyloidosis Aa according to GeneCards Suite gene sharing:

(showing 5, show less)
# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.86 APOA1 B2M CTSB LCAT SAA1 SAA2
2 extracellular region GO:0005576 9.81 APOA1 B2M CRP CTSB LCAT LPA
3 extracellular space GO:0005615 9.61 APOA1 B2M CRP CTSB LCAT SAA1
4 endocytic vesicle lumen GO:0071682 9.32 APOA1 SAA1
5 high-density lipoprotein particle GO:0034364 9.02 APOA1 LCAT SAA1 SAA2 SAA4

Biological processes related to Amyloidosis Aa according to GeneCards Suite gene sharing:

(showing 12, show less)
# Name GO ID Score Top Affiliating Genes
1 innate immune response GO:0045087 9.78 B2M CRP MEFV SAA1
2 negative regulation of inflammatory response GO:0050728 9.58 APOA1 MEFV SAA1
3 phosphatidylcholine biosynthetic process GO:0006656 9.51 APOA1 LCAT
4 cell chemotaxis GO:0060326 9.5 SAA1 SAA2 SAA4
5 cholesterol transport GO:0030301 9.49 APOA1 LCAT
6 reverse cholesterol transport GO:0043691 9.46 APOA1 LCAT
7 cellular protein metabolic process GO:0044267 9.46 APOA1 B2M SAA1 TTR
8 high-density lipoprotein particle remodeling GO:0034375 9.43 APOA1 LCAT
9 very-low-density lipoprotein particle remodeling GO:0034372 9.37 APOA1 LCAT
10 lipoprotein biosynthetic process GO:0042158 9.26 APOA1 LCAT
11 positive chemotaxis GO:0050918 9.13 SAA1 SAA2 SAA4
12 acute-phase response GO:0006953 8.92 CRP SAA1 SAA2 SAA4

Molecular functions related to Amyloidosis Aa according to GeneCards Suite gene sharing:

(showing 2, show less)
# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.35 APOA1 B2M CRP MEFV TTR
2 chemoattractant activity GO:0042056 8.8 SAA1 SAA2 SAA4

Sources for Amyloidosis Aa

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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