MCID: ANR006
MIFTS: 25

Anaerobic Pneumonia

Categories: Respiratory diseases

Aliases & Classifications for Anaerobic Pneumonia

MalaCards integrated aliases for Anaerobic Pneumonia:

Name: Anaerobic Pneumonia 12 15
Pneumonia Due to Anaerobes 12

Classifications:



External Ids:

Disease Ontology 12 DOID:873
ICD9CM 34 482.81
UMLS 71 C0375327

Summaries for Anaerobic Pneumonia

Disease Ontology : 12 An aspiration pneumonia caused by anaerobic bacteria like Bacteroides fragilis, Peptostreptococcus, anaerobic streptococci, Fusobacterium species (Fusobacterium nucleatum and Fusobacterium necrophoram). Lung abscess and empyema are diagnosed in this disease.

MalaCards based summary : Anaerobic Pneumonia, also known as pneumonia due to anaerobes, is related to pneumonia and anca-associated vasculitis. An important gene associated with Anaerobic Pneumonia is REG1B (Regenerating Family Member 1 Beta), and among its related pathways/superpathways are Toll-like Receptor Signaling Pathway and Transcriptional misregulation in cancer. Affiliated tissues include lung and monocytes, and related phenotypes are hematopoietic system and immune system

Related Diseases for Anaerobic Pneumonia

Diseases related to Anaerobic Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 83)
# Related Disease Score Top Affiliating Genes
1 pneumonia 28.6 TLR6 SERPINA1 MPO IL6 CCL5
2 anca-associated vasculitis 10.2 SERPINA1 MPO
3 microscopic colitis 10.1 LYZ IL6
4 aortitis 10.1 MPO IL6
5 scleral disease 10.1 MPO IL6
6 autoimmune disease of cardiovascular system 10.1 MPO IL6
7 neutrophilia, hereditary 10.1 MPO IL6
8 central nervous system vasculitis 10.1 MPO IL6
9 chlamydia pneumonia 10.1 TLR6 IL6
10 hypersensitivity reaction type iii disease 10.1 MPO IL6
11 bronchopneumonia 10.1 MPO IL6
12 plasma protein metabolism disease 10.0 SERPINA1 IL6
13 abdominal obesity-metabolic syndrome quantitative trait locus 2 10.0 SERPINE1 IL6
14 acute myocarditis 10.0 IL6 CD40
15 endometrial disease 10.0 TLR6 IL6
16 post-thrombotic syndrome 10.0 SERPINE1 IL6
17 streptococcus pneumonia 10.0 TLR6 IL6
18 pericardium disease 9.9 PCLAF MPO IL6
19 scorpion envenomation 9.9 IL6 CCL5
20 asbestosis 9.9 SERPINA1 MPO IL6
21 obesity-hypoventilation syndrome 9.9 IL6 CCL5
22 bronchiectasis 9.9 SERPINA1 MPO IL6
23 vasculitis 9.9 SERPINA1 MPO IL6
24 buerger disease 9.9 SERPINE1 MPO
25 stachybotrys chartarum 9.9 IL6 CCL5
26 coronary stenosis 9.8 SERPINE1 IL6 ADM2
27 idiopathic neutropenia 9.8 IL6 CCL5
28 african tick-bite fever 9.8 IL6 CCL5
29 herpangina 9.8 TLR6 IL6
30 maxillary sinusitis 9.8 MPO CCL5
31 cardiac tamponade 9.8
32 leukemia, acute monocytic 9.8 MPO IL6 CD40
33 viral pneumonia 9.8 IL6 CCL5
34 chronic eosinophilic pneumonia 9.8 IL6 CCL5
35 pneumoconiosis 9.8 SERPINE1 SERPINA1 IL6
36 hemorrhagic disease 9.7 SERPINE1 SERPINA1 MPO
37 parasitic protozoa infectious disease 9.7 TLR6 IL6 CD40
38 autoimmune disease of musculoskeletal system 9.7 TLR6 IL6 CD40
39 meningococcemia 9.7 SERPINE1 CCL5
40 vaginitis 9.7 IL6 CCL5
41 adult respiratory distress syndrome 9.7 SERPINE1 MPO IL6
42 meningitis 9.7 LYZ IL6 CCL5
43 infective endocarditis 9.7 TLR6 SERPINE1 IL6
44 endocarditis 9.7 TLR6 SERPINE1 IL6
45 viral meningitis 9.6 SERPINA1 IL6 CCL5
46 atherosclerosis susceptibility 9.6 SERPINE1 MPO IL6
47 radiculopathy 9.6 IL6 CCL5
48 pulmonary artery disease 9.6 SERPINE1 IL6
49 essential thrombocythemia 9.6 SERPINE1 MPO IL6
50 celiac disease 1 9.6 TLR6 IL6 CD40

Graphical network of the top 20 diseases related to Anaerobic Pneumonia:



Diseases related to Anaerobic Pneumonia

Symptoms & Phenotypes for Anaerobic Pneumonia

MGI Mouse Phenotypes related to Anaerobic Pneumonia:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.56 CCL5 CD40 IL6 LYZ MPO PCLAF
2 immune system MP:0005387 9.23 CCL5 CD40 IL6 LYZ MPO PCLAF

Drugs & Therapeutics for Anaerobic Pneumonia

Search Clinical Trials , NIH Clinical Center for Anaerobic Pneumonia

Genetic Tests for Anaerobic Pneumonia

Anatomical Context for Anaerobic Pneumonia

MalaCards organs/tissues related to Anaerobic Pneumonia:

40
Lung, Monocytes

Publications for Anaerobic Pneumonia

Articles related to Anaerobic Pneumonia:

# Title Authors PMID Year
1
Infected pneumatocele following anaerobic pneumonia in adult. 61
16491835 2005
2
Tension pneumopericardium caused by positive pressure ventilation complicating anaerobic pneumonia. 61
12735423 2003
3
[Anaerobic pneumonia]. 61
10088425 1999
4
[Anaerobic pneumonia]. 61
8151972 1994
5
Pneumonia. Patient profiles, choice of empiric therapy, and the place of third-generation cephalosporins. 61
1730186 1992
6
[Effect of metronidazole on the course of experimental anaerobic streptococcal pneumonia]. 61
3765970 1986
7
Anaerobic infections and their therapy. 61
7450861 1980

Variations for Anaerobic Pneumonia

Expression for Anaerobic Pneumonia

Search GEO for disease gene expression data for Anaerobic Pneumonia.

Pathways for Anaerobic Pneumonia

GO Terms for Anaerobic Pneumonia

Cellular components related to Anaerobic Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.73 SERPINE1 SERPINA1 REG1B MPO LYZ CD40
2 cell GO:0005623 9.55 TLR6 MPO IL6 CD40 CCL5
3 extracellular space GO:0005615 9.5 SERPINE1 SERPINA1 REG1B MPO LYZ IL6
4 extracellular region GO:0005576 9.28 SERPINE1 SERPINA1 REG1B MPO LYZ IL6

Biological processes related to Anaerobic Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.63 SERPINA1 LYZ IL6
2 cellular response to lipopolysaccharide GO:0071222 9.58 SERPINE1 IL6 CD40
3 positive regulation of angiogenesis GO:0045766 9.54 SERPINE1 CD40 ADM2
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.5 TLR6 IL6 CD40
5 acute-phase response GO:0006953 9.48 SERPINA1 IL6
6 positive regulation of JAK-STAT cascade GO:0046427 9.43 IL6 CCL5
7 defense response to Gram-negative bacterium GO:0050829 9.33 SERPINE1 LYZ IL6
8 positive regulation of monocyte chemotaxis GO:0090026 9.26 SERPINE1 CCL5
9 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.13 IL6 CD40 CCL5
10 inflammatory response GO:0006954 9.02 TLR6 LYZ IL6 CD40 CCL5

Sources for Anaerobic Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....