MCID: ANR006
MIFTS: 30

Anaerobic Pneumonia

Categories: Infectious diseases, Respiratory diseases

Aliases & Classifications for Anaerobic Pneumonia

MalaCards integrated aliases for Anaerobic Pneumonia:

Name: Anaerobic Pneumonia 12 15
Pneumonia Due to Anaerobes 12

Classifications:



External Ids:

Disease Ontology 12 DOID:873
ICD9CM 34 482.81
UMLS 71 C0375327

Summaries for Anaerobic Pneumonia

Disease Ontology : 12 An aspiration pneumonia caused by anaerobic bacteria like Bacteroides fragilis, Peptostreptococcus, anaerobic streptococci, Fusobacterium species (Fusobacterium nucleatum and Fusobacterium necrophoram). Lung abscess and empyema are diagnosed in this disease.

MalaCards based summary : Anaerobic Pneumonia, also known as pneumonia due to anaerobes, is related to pneumonia and physiological polycythemia. An important gene associated with Anaerobic Pneumonia is REG1B (Regenerating Family Member 1 Beta), and among its related pathways/superpathways are Toll-like Receptor Signaling Pathway and Measles. Affiliated tissues include lung, and related phenotypes are hematopoietic system and immune system

Related Diseases for Anaerobic Pneumonia

Diseases related to Anaerobic Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 420)
# Related Disease Score Top Affiliating Genes
1 pneumonia 28.7 TNF SERPINA1 MPO IL6 IL1B CCL5
2 physiological polycythemia 10.4 TNF IL1B
3 external pathological resorption 10.4 TNF IL6
4 systemic onset juvenile idiopathic arthritis 10.4 TNF IL1B
5 staphylococcal toxic shock syndrome 10.4 TNF IL1B
6 opportunistic bacterial infectious disease 10.3 TNF LYZ
7 nocardiosis 10.3 TNF LYZ
8 vulvar vestibulitis syndrome 10.3 TNF IL1B
9 idiopathic anterior uveitis 10.3 TNF IL6
10 palladium allergic contact dermatitis 10.3 TNF IL1B
11 kashin-beck disease 10.3 TNF IL1B
12 streptococcal toxic-shock syndrome 10.3 TNF IL6
13 angioimmunoblastic lymphadenopathy with dysproteinemia 10.3 TNF IL6
14 congenital cytomegalovirus 10.3 TNF IL1B
15 jejunoileitis 10.3 TNF IL1B
16 prosthetic joint infection 10.3 IL6 IL1B
17 periodontitis, chronic 10.3 IL6 IL1B
18 metal allergy 10.3 TNF IL1B
19 actinic prurigo 10.3 TNF IL1B
20 null-cell leukemia 10.3 TNF IL6
21 uremic pruritus 10.3 IL6 IL1B
22 indolent myeloma 10.3 IL6 IL1B
23 posterior urethral valves 10.3 TNF IL6
24 autoimmune inner ear disease 10.3 TNF MPO
25 glomeruloid hemangioma 10.3 IL6 IL1B
26 photokeratitis 10.3 IL6 IL1B
27 post-transplant lymphoproliferative disease 10.3 TNF IL6
28 post-cardiac arrest syndrome 10.2 TNF IL6
29 microscopic polyangiitis 10.2 TNF MPO
30 palindromic rheumatism 10.2 TNF IL1B
31 transverse myelitis 10.2 TNF IL6
32 tracheitis 10.2 TNF IL6
33 suppurative periapical periodontitis 10.2 IL6 IL1B
34 anthracosis 10.2 TNF IL1B
35 spotted fever rickettsiosis 10.2 TNF CCL5
36 mycobacterium abscessus 10.2 TNF SERPINA1
37 heart aneurysm 10.2 TNF IL6
38 tuberculous meningitis 10.2 TNF LYZ
39 coronary aneurysm 10.2 TNF IL6
40 hypopyon 10.2 TNF IL6
41 recurrent corneal erosion 10.2 IL6 IL1B
42 amebiasis 10.2 TNF REG1B IL1B
43 obesity-hypoventilation syndrome 10.2 IL6 CCL5
44 tenosynovitis 10.2 TNF IL6
45 blastomycosis 10.2 TNF IL6
46 retinitis pigmentosa 55 10.2 TNF IL6
47 orofacial granulomatosis 10.2 TNF CCL5
48 mononeuritis of upper limb and mononeuritis multiplex 10.2 TNF MPO
49 mononeuritis multiplex 10.1 TNF MPO
50 lumbosacral lipoma 10.1 TNF IL1B

Graphical network of the top 20 diseases related to Anaerobic Pneumonia:



Diseases related to Anaerobic Pneumonia

Symptoms & Phenotypes for Anaerobic Pneumonia

MGI Mouse Phenotypes related to Anaerobic Pneumonia:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.85 ADM2 CCL5 CD40 IL1B IL6 LYZ
2 immune system MP:0005387 9.65 ADM2 CCL5 CD40 IL1B IL6 LYZ
3 liver/biliary system MP:0005370 9.1 ADM2 IL6 LYZ REG1B SERPINE1 TNF

Drugs & Therapeutics for Anaerobic Pneumonia

Search Clinical Trials , NIH Clinical Center for Anaerobic Pneumonia

Genetic Tests for Anaerobic Pneumonia

Anatomical Context for Anaerobic Pneumonia

MalaCards organs/tissues related to Anaerobic Pneumonia:

40
Lung

Publications for Anaerobic Pneumonia

Articles related to Anaerobic Pneumonia:

# Title Authors PMID Year
1
Anaerobic Necrotizing Pneumonia: Another Potential Life-threatening Complication of Vaping? 61
32132153 2020
2
Infected pneumatocele following anaerobic pneumonia in adult. 61
16491835 2005
3
Tension pneumopericardium caused by positive pressure ventilation complicating anaerobic pneumonia. 61
12735423 2003
4
[Anaerobic pneumonia]. 61
10088425 1999
5
[Anaerobic pneumonia]. 61
8151972 1994
6
Pneumonia. Patient profiles, choice of empiric therapy, and the place of third-generation cephalosporins. 61
1730186 1992
7
[Effect of metronidazole on the course of experimental anaerobic streptococcal pneumonia]. 61
3765970 1986
8
Anaerobic infections and their therapy. 61
7450861 1980

Variations for Anaerobic Pneumonia

Expression for Anaerobic Pneumonia

Search GEO for disease gene expression data for Anaerobic Pneumonia.

Pathways for Anaerobic Pneumonia

Pathways related to Anaerobic Pneumonia according to GeneCards Suite gene sharing:

(show all 42)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.87 TNF SERPINE1 IL6 IL1B CD40 CCL5
2
Show member pathways
12.69 TNF IL6 IL1B CD40 CCL5
3
Show member pathways
12.61 TNF SERPINE1 IL6 IL1B
4
Show member pathways
12.59 TNF IL6 IL1B CD40
5
Show member pathways
12.47 TNF MPO IL6 IL1B
6 12.43 TNF MPO IL1B CCL5
7 12.12 TNF IL6 IL1B CCL5
8 12.07 TNF IL6 IL1B
9 11.97 TNF SERPINE1 IL6
10 11.92 TNF IL6 IL1B
11 11.92 TNF IL6 IL1B
12 11.9 TNF MPO IL6
13 11.89 TNF IL6 IL1B
14 11.85 SERPINE1 IL6 IL1B
15
Show member pathways
11.85 TNF IL6 IL1B
16 11.83 TNF IL1B CD40
17 11.81 TNF IL6 IL1B
18 11.79 TNF IL6 IL1B
19 11.78 TNF IL6 IL1B CCL5
20
Show member pathways
11.77 TNF SERPINE1 MPO IL6 IL1B CCL5
21 11.71 TNF SERPINE1 IL6 IL1B
22 11.67 TNF IL6 IL1B
23 11.65 TNF IL6 IL1B
24 11.64 TNF IL6 IL1B CCL5
25
Show member pathways
11.57 TNF IL6 IL1B
26 11.52 TNF IL6 IL1B
27 11.43 TNF MPO IL6
28 11.4 TNF IL6 IL1B
29 11.29 TNF IL6 IL1B
30 11.26 IL6 IL1B CCL5
31 11.26 TNF IL6 IL1B CD40
32 11.24 TNF IL6 IL1B
33 11.18 TNF IL6 IL1B
34 11.15 TNF IL6 IL1B CCL5
35 11.14 TNF IL6 IL1B
36 11.1 TNF IL6 IL1B
37 11.03 TNF IL6
38 11.02 TNF IL1B
39 10.96 TNF IL6
40 10.82 TNF SERPINA1 IL6 IL1B CCL5
41 10.72 IL6 IL1B
42 10.7 TNF MPO IL1B

GO Terms for Anaerobic Pneumonia

Cellular components related to Anaerobic Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.65 TNF SERPINE1 SERPINA1 REG1B MPO LYZ
2 extracellular region GO:0005576 9.36 TNF SERPINE1 SERPINA1 REG1B MPO LYZ

Biological processes related to Anaerobic Pneumonia according to GeneCards Suite gene sharing:

(show all 38)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.92 TNF IL6 IL1B CCL5
2 positive regulation of DNA-binding transcription factor activity GO:0051091 9.82 TNF IL6 IL1B
3 defense response to Gram-positive bacterium GO:0050830 9.81 TNF LYZ IL6
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.81 TNF IL6 IL1B CD40
5 positive regulation of inflammatory response GO:0050729 9.8 TNF SERPINE1 IL1B
6 defense response to Gram-negative bacterium GO:0050829 9.8 SERPINE1 LYZ IL6
7 positive regulation of angiogenesis GO:0045766 9.8 SERPINE1 IL1B CD40 ADM2
8 regulation of insulin secretion GO:0050796 9.77 TNF IL1B CCL5
9 cellular response to organic cyclic compound GO:0071407 9.77 TNF IL1B CCL5
10 positive regulation of T cell proliferation GO:0042102 9.76 IL6 IL1B CCL5
11 positive regulation of smooth muscle cell proliferation GO:0048661 9.75 TNF IL6 CCL5
12 positive regulation of interleukin-6 production GO:0032755 9.72 TNF IL6 IL1B
13 positive regulation of chemokine production GO:0032722 9.68 TNF IL6
14 positive regulation of monocyte chemotaxis GO:0090026 9.67 SERPINE1 CCL5
15 negative regulation of lipid catabolic process GO:0050995 9.67 TNF IL1B
16 astrocyte activation GO:0048143 9.67 TNF IL1B
17 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.66 TNF IL1B
18 positive regulation of interleukin-6 biosynthetic process GO:0045410 9.66 TNF IL1B
19 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.65 TNF IL1B
20 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.65 TNF IL6
21 lipopolysaccharide-mediated signaling pathway GO:0031663 9.65 TNF IL1B CCL5
22 positive regulation of chemokine biosynthetic process GO:0045080 9.64 TNF IL1B
23 negative regulation of lipid storage GO:0010888 9.63 TNF IL6
24 positive regulation of JAK-STAT cascade GO:0046427 9.63 TNF IL6 CCL5
25 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.62 TNF IL6 CD40 CCL5
26 regulation of establishment of endothelial barrier GO:1903140 9.61 TNF IL1B
27 negative regulation of vascular wound healing GO:0061044 9.61 TNF SERPINE1
28 positive regulation of interleukin-8 production GO:0032757 9.61 TNF SERPINE1 IL1B
29 negative regulation of neurogenesis GO:0050768 9.58 TNF IL6 IL1B
30 regulation of immunoglobulin secretion GO:0051023 9.57 TNF CD40
31 positive regulation of fever generation GO:0031622 9.56 TNF IL1B
32 cellular response to lipopolysaccharide GO:0071222 9.55 TNF SERPINE1 IL6 IL1B CD40
33 sequestering of triglyceride GO:0030730 9.54 TNF IL1B
34 positive regulation of glial cell proliferation GO:0060252 9.54 TNF IL6 IL1B
35 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.52 TNF IL1B
36 positive regulation of neuroinflammatory response GO:0150078 9.43 TNF IL6 IL1B
37 inflammatory response GO:0006954 9.43 TNF LYZ IL6 IL1B CD40 CCL5
38 protein kinase B signaling GO:0043491 8.92 TNF IL1B CD40 CCL5

Molecular functions related to Anaerobic Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 9.13 TNF SERPINE1 SERPINA1
2 cytokine activity GO:0005125 8.92 TNF IL6 IL1B CCL5

Sources for Anaerobic Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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