MCID: ANL012
MIFTS: 25

Anal Gland Adenocarcinoma

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases

Aliases & Classifications for Anal Gland Adenocarcinoma

MalaCards integrated aliases for Anal Gland Adenocarcinoma:

Name: Anal Gland Adenocarcinoma 12 15
Adenocarcinoma of Anal Glands 70
Adenocarcinoma of Anal Ducts 12
Adenocarcinoma of Anal Gland 12
Anal Glands Adenocarcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7531
NCIt 50 C5609
SNOMED-CT 67 128655006
UMLS 70 C1266027

Summaries for Anal Gland Adenocarcinoma

Disease Ontology : 12 An anus carcinoma that derives from epithelial cells of glandular origin located in the anal gland.

MalaCards based summary : Anal Gland Adenocarcinoma, also known as adenocarcinoma of anal glands, is related to appendix adenocarcinoma and adenocarcinoma in situ. An important gene associated with Anal Gland Adenocarcinoma is CD320 (CD320 Molecule), and among its related pathways/superpathways are Diseases of metabolism and Cobalamin (Cbl, vitamin B12) transport and metabolism. Affiliated tissues include anal gland, appendix and breast.

Related Diseases for Anal Gland Adenocarcinoma

Diseases related to Anal Gland Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 112)
# Related Disease Score Top Affiliating Genes
1 appendix adenocarcinoma 30.0 KRT7 CDX2
2 adenocarcinoma in situ 29.8 KRT7 CDX2
3 anal canal adenocarcinoma 29.3 MUC5AC KRT7 CDX2
4 mucinous adenocarcinoma 29.3 MUC5AC KRT7 CDX2
5 spleen angiosarcoma 10.1 TCN2 CD320
6 teratoma 10.0 KRT7 CDX2
7 cervical adenocarcinoma 10.0 KRT7 CDX2
8 ovary neuroendocrine neoplasm 10.0 KRT7 CDX2
9 anal canal paget's disease 10.0 KRT7 CDX2
10 anal paget's disease 10.0 KRT7 CDX2
11 gastric signet ring cell adenocarcinoma 10.0 KRT7 CDX2
12 ureter adenocarcinoma 10.0 KRT7 CDX2
13 mucinous adenofibroma 10.0 KRT7 CDX2
14 pancreatic foamy gland adenocarcinoma 10.0 KRT7 CDX2
15 adenosquamous colon carcinoma 10.0 KRT7 CDX2
16 bartholin's gland disease 10.0 KRT7 CDX2
17 bartholin's gland carcinoma 10.0 KRT7 CDX2
18 vulva adenocarcinoma 10.0 KRT7 CDX2
19 vitamin metabolic disorder 10.0 TCN2 CD320
20 vaginal tubulovillous adenoma 10.0 KRT7 CDX2
21 female urethral cancer 10.0 KRT7 CDX2
22 cystitis cystica 10.0 KRT7 CDX2
23 ovarian seromucinous carcinoma 10.0 KRT7 CDX2
24 rectum neuroendocrine neoplasm 10.0 KRT7 CDX2
25 mucinous ovarian cystadenoma 10.0 KRT7 CDX2
26 sigmoid neoplasm 10.0 KRT7 CDX2
27 krukenberg carcinoma 10.0 KRT7 CDX2
28 jejunal cancer 10.0 KRT7 CDX2
29 appendiceal neoplasm 10.0 KRT7 CDX2
30 mucinous bronchioloalveolar adenocarcinoma 10.0 KRT7 CDX2
31 jejunal adenocarcinoma 10.0 KRT7 CDX2
32 gastric diffuse adenocarcinoma 10.0 KRT7 CDX2
33 vitamin b12 deficiency 10.0 TCN2 CD320
34 linitis plastica 10.0 KRT7 CDX2
35 mucinous stomach adenocarcinoma 10.0 KRT7 CDX2
36 hereditary lymphedema i 10.0
37 mammary paget's disease 10.0
38 in situ carcinoma 10.0
39 esophageal adenosquamous carcinoma 10.0 KRT7 CDX2
40 vaginal adenoma 10.0 KRT7 CDX2
41 vaginal benign neoplasm 10.0 KRT7 CDX2
42 thymus clear cell carcinoma 10.0 KRT7 CDX2
43 bladder clear cell adenocarcinoma 10.0 KRT7 CDX2
44 clear cell basal cell carcinoma 10.0 KRT7 CDX2
45 nasal cavity olfactory neuroblastoma 10.0 KRT7 CDX2
46 cervical adenoma malignum 10.0 KRT7 CDX2
47 peritoneal serous adenocarcinoma 10.0 KRT7 CDX2
48 breast neuroendocrine neoplasm 10.0 KRT7 CDX2
49 epididymis adenocarcinoma 10.0 KRT7 CDX2
50 epididymis cancer 10.0 KRT7 CDX2

Graphical network of the top 20 diseases related to Anal Gland Adenocarcinoma:



Diseases related to Anal Gland Adenocarcinoma

Symptoms & Phenotypes for Anal Gland Adenocarcinoma

Drugs & Therapeutics for Anal Gland Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Anal Gland Adenocarcinoma

Genetic Tests for Anal Gland Adenocarcinoma

Anatomical Context for Anal Gland Adenocarcinoma

The Foundational Model of Anatomy Ontology organs/tissues related to Anal Gland Adenocarcinoma:

19
Anal Gland

MalaCards organs/tissues related to Anal Gland Adenocarcinoma:

40
Appendix, Breast, Ovary, Spleen, Thymus, Small Intestine, Colon

Publications for Anal Gland Adenocarcinoma

Articles related to Anal Gland Adenocarcinoma:

(show all 14)
# Title Authors PMID Year
1
Evaluation of radiographs for the detection of sublumbar lymphadenopathy in dogs. 61
32655159 2020
2
Rescue surgery for advanced anal gland adenocarcinoma: A case report. 61
31078011 2019
3
Early anal gland adenocarcinoma with a characteristic submucosal tumor-like appearance: a case report. 61
30031391 2018
4
Anal gland adenocarcinoma in situ with pagetoid spread: a case report. 61
29943205 2018
5
A preliminary investigation of the effect of sample collection technique on the cell and RNA content of fine-needle aspirates of five canine tumours. 61
29193082 2018
6
Renal vein tumor thrombus from metastatic anal gland adenocarcinoma. 61
29147643 2018
7
The Use of Liposomes and Nanoparticles as Drug Delivery Systems to Improve Cancer Treatment in Dogs and Cats. 61
29215573 2017
8
Pigmented anal gland adenocarcinoma with associated pagetoid spread. 61
23330913 2013
9
Successful treatment of anal gland adenocarcinoma with combined modality therapy. 61
22690260 2012
10
[Anal gland adenocarcinoma]. 61
21267837 2011
11
[Anal gland carcinoma with osteoblastic metastases]. 61
9762050 1998
12
Histopathologic features and post-surgical sequelae of 57 cutaneous neoplasms in ferrets (Mustela putorius furo L.). 61
8116142 1993
13
Adenocarcinoma of the anal glands. Results of a survey. 61
8458266 1993
14
Anal gland adenocarcinoma presenting as painless scrotal swelling in a 73-year-old man: a case report. 61
6893614 1980

Variations for Anal Gland Adenocarcinoma

Expression for Anal Gland Adenocarcinoma

Search GEO for disease gene expression data for Anal Gland Adenocarcinoma.

Pathways for Anal Gland Adenocarcinoma

GO Terms for Anal Gland Adenocarcinoma

Biological processes related to Anal Gland Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cobalamin metabolic process GO:0009235 8.96 TCN2 CD320
2 cobalamin transport GO:0015889 8.62 TCN2 CD320

Molecular functions related to Anal Gland Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cobalamin binding GO:0031419 8.62 TCN2 CD320

Sources for Anal Gland Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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