MCID: ANL012
MIFTS: 28

Anal Gland Adenocarcinoma

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases

Aliases & Classifications for Anal Gland Adenocarcinoma

MalaCards integrated aliases for Anal Gland Adenocarcinoma:

Name: Anal Gland Adenocarcinoma 12 15
Adenocarcinoma of Anal Glands 74
Adenocarcinoma of Anal Ducts 12
Adenocarcinoma of Anal Gland 12
Anal Glands Adenocarcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7531
NCIt 51 C5609
UMLS 74 C1266027

Summaries for Anal Gland Adenocarcinoma

Disease Ontology : 12 An anus carcinoma that derives from epithelial cells of glandular origin located in the anal gland.

MalaCards based summary : Anal Gland Adenocarcinoma, also known as adenocarcinoma of anal glands, is related to adenocarcinoma and cystadenocarcinoma. An important gene associated with Anal Gland Adenocarcinoma is KRT7 (Keratin 7), and among its related pathways/superpathways is Cytoskeleton remodeling Neurofilaments. Affiliated tissues include breast, lung and ovary.

Related Diseases for Anal Gland Adenocarcinoma

Diseases related to Anal Gland Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 97)
# Related Disease Score Top Affiliating Genes
1 adenocarcinoma 10.4
2 cystadenocarcinoma 10.1 CEACAM5 KRT7
3 cutaneous mucoepidermoid carcinoma 10.1 CEACAM5 KRT7
4 mucinous adenofibroma 10.1 CEACAM5 KRT7
5 malignant spiradenoma 10.1 CEACAM5 KRT7
6 nodular hidradenoma 10.1 CEACAM5 KRT7
7 vulval paget's disease 10.1 CEACAM5 KRT7
8 adenoid basal cell carcinoma 10.1 CEACAM5 KRT7
9 pancreatic serous cystadenoma 10.1 CEACAM5 KRT7
10 thymus adenocarcinoma 10.1 CEACAM5 KRT7
11 meibomian cyst 10.1 CEACAM5 KRT7
12 vulva adenocarcinoma 10.1 CEACAM5 KRT7
13 malignant biphasic mesothelioma 10.1 CEACAM5 KRT7
14 rectum adenocarcinoma 10.1 CEACAM5 KRT7
15 prostate squamous cell carcinoma 10.1 CEACAM5 KRT7
16 warthin tumor 10.1 CEACAM5 KRT7
17 breast adenomyoepithelioma 10.1 CEACAM5 KRT7
18 breast myoepithelial neoplasm 10.1 CEACAM5 KRT7
19 infiltrative basal cell carcinoma 10.1 CEACAM5 KRT7
20 mixed cell type cancer 10.1 CEACAM5 KRT7
21 breast mucoepidermoid carcinoma 10.1 CEACAM5 MUC5AC
22 solid adenocarcinoma with mucin production 10.1 KRT7 MUC5AC
23 papillary adenocarcinoma 10.1 CEACAM5 KRT7
24 clear cell adenoma 10.1 CEACAM5 MUC5AC
25 gastrointestinal system benign neoplasm 10.1 CEACAM5 KRT7
26 ovary adenocarcinoma 10.0 CEACAM5 KRT7
27 ovarian cancer 1 10.0 CEACAM5 KRT7
28 malignant ovarian surface epithelial-stromal neoplasm 10.0 CEACAM5 KRT7
29 ovary epithelial cancer 10.0 CEACAM5 KRT7
30 large cell carcinoma 10.0 CEACAM5 KRT7
31 cell type benign neoplasm 10.0 CEACAM5 KRT7
32 hidradenocarcinoma 10.0 KRT7 MUC5AC
33 pseudomyxoma peritonei 10.0 KRT7 MUC5AC
34 colorectal adenocarcinoma 10.0 CEACAM5 KRT7
35 gastric tubular adenocarcinoma 10.0 KRT7 MUC5AC
36 cystitis cystica 10.0 KRT7 MUC5AC
37 adenocarcinoma in situ 10.0
38 intrahepatic bile duct adenoma 10.0 KRT19 KRT7
39 proliferating trichilemmal cyst 10.0 KRT19 KRT7
40 splenic tuberculosis 10.0 CEACAM5 KRT19
41 renal pelvis adenocarcinoma 10.0 KRT19 KRT7
42 basal cell carcinoma 9.9 KRT19 KRT7
43 bladder carcinoma in situ 9.9 KRT19 KRT7
44 malignant leydig cell tumor 9.9 KRT19 KRT7
45 stomach disease 9.9 CEACAM5 MUC5AC
46 corneal abscess 9.9 KRT19 KRT7
47 chondroid lipoma 9.9 KRT19 KRT7
48 renal pelvis carcinoma 9.9 KRT19 KRT7
49 mucinous tubular and spindle renal cell carcinoma 9.9 KRT19 KRT7
50 lipoadenoma 9.9 KRT19 KRT7

Graphical network of the top 20 diseases related to Anal Gland Adenocarcinoma:



Diseases related to Anal Gland Adenocarcinoma

Symptoms & Phenotypes for Anal Gland Adenocarcinoma

Drugs & Therapeutics for Anal Gland Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Anal Gland Adenocarcinoma

Genetic Tests for Anal Gland Adenocarcinoma

Anatomical Context for Anal Gland Adenocarcinoma

MalaCards organs/tissues related to Anal Gland Adenocarcinoma:

42
Breast, Lung, Ovary, Pancreas, Thymus, Kidney, Liver

The Foundational Model of Anatomy Ontology organs/tissues related to Anal Gland Adenocarcinoma:

20
The Anal Gl

Publications for Anal Gland Adenocarcinoma

Articles related to Anal Gland Adenocarcinoma:

# Title Authors Year
1
Rescue surgery for advanced anal gland adenocarcinoma: A case report. ( 31078011 )
2019
2
Renal vein tumor thrombus from metastatic anal gland adenocarcinoma. ( 29147643 )
2018
3
Early anal gland adenocarcinoma with a characteristic submucosal tumor-like appearance: a case report. ( 30031391 )
2018
4
Anal gland adenocarcinoma in situ with pagetoid spread: a case report. ( 29943205 )
2018
5
Pigmented anal gland adenocarcinoma with associated pagetoid spread. ( 23330913 )
2013
6
Successful treatment of anal gland adenocarcinoma with combined modality therapy. ( 22690260 )
2012
7
Anal gland adenocarcinoma presenting as painless scrotal swelling in a 73-year-old man: a case report. ( 6893614 )
1980

Variations for Anal Gland Adenocarcinoma

Expression for Anal Gland Adenocarcinoma

Search GEO for disease gene expression data for Anal Gland Adenocarcinoma.

Pathways for Anal Gland Adenocarcinoma

Pathways related to Anal Gland Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.66 KRT19 KRT7

GO Terms for Anal Gland Adenocarcinoma

Cellular components related to Anal Gland Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.96 KRT19 KRT7
2 extracellular exosome GO:0070062 8.92 CEACAM5 KRT19 KRT7 MUC5AC

Biological processes related to Anal Gland Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 8.96 KRT19 KRT7
2 cornification GO:0070268 8.62 KRT19 KRT7

Sources for Anal Gland Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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