MCID: ANL006
MIFTS: 21

Anal Paget's Disease

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Anal Paget's Disease

MalaCards integrated aliases for Anal Paget's Disease:

Name: Anal Paget's Disease 12 15
Paget's Disease of the Anus 12
Paget Disease of the Anus 70
Paget's Disease of Anus 12
Anal Paget Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3446
NCIt 50 C5598
UMLS 70 C1332274

Summaries for Anal Paget's Disease

MalaCards based summary : Anal Paget's Disease, also known as paget's disease of the anus, is related to papillary adenoma and mammary paget's disease. An important gene associated with Anal Paget's Disease is MFGE8 (Milk Fat Globule EGF And Factor V/VIII Domain Containing). Affiliated tissues include colon, breast and kidney.

Related Diseases for Anal Paget's Disease

Diseases related to Anal Paget's Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 228)
# Related Disease Score Top Affiliating Genes
1 papillary adenoma 30.2 KRT7 CEACAM5
2 mammary paget's disease 29.9 PIP KRT7
3 ovary neuroendocrine neoplasm 10.1 KRT7 CDX2
4 anal gland adenocarcinoma 10.1 KRT7 CDX2
5 anus adenocarcinoma 10.1 KRT7 CDX2
6 adenosquamous colon carcinoma 10.1 KRT7 CDX2
7 cystitis cystica 10.1 KRT7 CDX2
8 mucinous intrahepatic cholangiocarcinoma 10.1 KRT7 CDX2
9 ovarian seromucinous carcinoma 10.1 KRT7 CDX2
10 rectum neuroendocrine neoplasm 10.1 KRT7 CDX2
11 jejunal cancer 10.1 KRT7 CDX2
12 apocrine adenocarcinoma 10.1 PIP KRT7
13 appendix adenocarcinoma 10.1 KRT7 CDX2
14 mucinous bronchioloalveolar adenocarcinoma 10.1 KRT7 CDX2
15 jejunal adenocarcinoma 10.1 KRT7 CDX2
16 glandular cystitis 10.1 KRT7 CDX2
17 vaginal adenoma 10.1 KRT7 CDX2
18 adenoma 10.1
19 ceruminoma 10.1 PIP KRT7
20 vaginal benign neoplasm 10.1 KRT7 CDX2
21 bladder clear cell adenocarcinoma 10.1 KRT7 CDX2
22 cervical adenoma malignum 10.1 KRT7 CDX2
23 oncocytic breast carcinoma 10.1 PIP KRT7
24 ceruminous adenocarcinoma 10.1 PIP KRT7
25 epididymis adenocarcinoma 10.1 KRT7 CDX2
26 epididymis cancer 10.1 KRT7 CDX2
27 meckel diverticulum 10.1 KRT7 CDX2
28 eyelid carcinoma 10.1 PIP KRT7
29 bladder adenocarcinoma 10.1 KRT7 CDX2
30 laryngeal mucoepidermoid carcinoma 10.1 CEACAM5 CDX2
31 breast mucinous carcinoma 10.1 PIP KRT7
32 thymus adenocarcinoma 10.1 CEACAM5 CDX2
33 chronic cystitis 10.1 KRT7 CDX2
34 erysipeloid 10.1 PIP KRT7
35 descending colon cancer 10.1 CEACAM5 CDX2
36 dacryocystocele 10.1 PIP KRT7
37 horseshoe kidney 10.1 KRT7 CDX2
38 chronic inflammation of lacrimal passage 10.1 PIP KRT7
39 lymphangioma 10.1 CEACAM5 CDX2
40 tinea cruris 10.1 PIP KRT7
41 ovarian cystadenoma 10.1 KRT7 CEACAM5
42 cystadenoma 10.1 KRT7 CEACAM5
43 syringoma 10.1 KRT7 CEACAM5
44 adenosquamous carcinoma 10.1 KRT7 CEACAM5
45 papillary cystadenocarcinoma 10.1 PIP KRT7
46 ascending colon cancer 10.0 CEACAM5 CDX2
47 cribriform carcinoma 10.0 PIP KRT7
48 leukoplakia of penis 10.0 KRT7 CEACAM5
49 colon neuroendocrine neoplasm 10.0 CEACAM5 CDX2
50 malignant exocrine pancreas neoplasm 10.0 CEACAM5 CDX2

Graphical network of the top 20 diseases related to Anal Paget's Disease:



Diseases related to Anal Paget's Disease

Symptoms & Phenotypes for Anal Paget's Disease

Drugs & Therapeutics for Anal Paget's Disease

Search Clinical Trials , NIH Clinical Center for Anal Paget's Disease

Genetic Tests for Anal Paget's Disease

Anatomical Context for Anal Paget's Disease

MalaCards organs/tissues related to Anal Paget's Disease:

40
Colon, Breast, Kidney, Lung, Appendix, Skin, Thymus

Publications for Anal Paget's Disease

Articles related to Anal Paget's Disease:

(show all 21)
# Title Authors PMID Year
1
High Risk of Proximal and Local Neoplasms in 2206 Patients With Anogenital Extramammary Paget's Disease. 61
31567917 2019
2
Primary peri-anal adenocarcinoma of intestinal type - a new proposed entity. 61
29464744 2018
3
Paget's disease of the anus masking a mixed adenoneuroendocrine tumour of the rectum. 61
28196824 2017
4
Perianal Paget's disease: case report and review of the literature. 61
27426653 2016
5
Perianal Paget's disease treated with wide excision and gluteal skin flap reconstruction: report of a case and review of the literature. 61
18584248 2008
6
Anal intraepithelial neoplasia and other neoplastic precursor lesions of the anal canal and perianal region. 61
17996800 2007
7
Wide local excision and split-thickness skin graft for circumferential Paget's disease of the anus. 61
15006574 2004
8
Perianal Paget's disease: report of five cases. 61
1328429 1992
9
Paget's disease of the anus. 61
1648135 1991
10
Paget's disease of the anus. 61
1847974 1991
11
Paget's disease of the anus: a clinicopathological study. 61
2537129 1989
12
Carcinoma of the anus. 61
189707 1976
13
[Clinical aspects and therapy of an extramammary, anal Paget's disease]. 61
4358828 1973
14
Paget's disease of the anus secondary to a malignant papillary adenoma of the rectum. 61
4347585 1973
15
Extramammary Paget's disease of the anus. 61
4338480 1972
16
Extramammary Paget's disease of the anus. 61
4300441 1968
17
OCCULT PAGET'S DISEASE OF THE ANUS: REPORT OF A CASE. 61
14323718 1965
18
EXTRAMAMMARY PAGET'S DISEASE OF THE ANUS. 61
14123468 1964
19
[Paget's disease of the anus. Apropos of a further case]. 61
13908147 1962
20
Paget's disease of the anus. 61
13372940 1957
21
Paget's disease of the anus; case report. 61
13104750 1953

Variations for Anal Paget's Disease

Expression for Anal Paget's Disease

Search GEO for disease gene expression data for Anal Paget's Disease.

Pathways for Anal Paget's Disease

GO Terms for Anal Paget's Disease

Sources for Anal Paget's Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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