MCID: ANP032
MIFTS: 16

Anaplastic Pleomorphic Xanthoastrocytoma

Categories: Bone diseases, Cancer diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Anaplastic Pleomorphic Xanthoastrocytoma

MalaCards integrated aliases for Anaplastic Pleomorphic Xanthoastrocytoma:

Name: Anaplastic Pleomorphic Xanthoastrocytoma 12 20

Classifications:



External Ids:

Disease Ontology 12 DOID:0080854
NCIt 50 C129327

Summaries for Anaplastic Pleomorphic Xanthoastrocytoma

Disease Ontology : 12 A malignant astrocytoma that is characterized by the presence of five or more mitoses per 10 high-power fields.

MalaCards based summary : Anaplastic Pleomorphic Xanthoastrocytoma is related to pleomorphic xanthoastrocytoma and glioblastoma. An important gene associated with Anaplastic Pleomorphic Xanthoastrocytoma is TP53 (Tumor Protein P53). Affiliated tissues include brain and cerebellum.

Related Diseases for Anaplastic Pleomorphic Xanthoastrocytoma

Diseases related to Anaplastic Pleomorphic Xanthoastrocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 20)
# Related Disease Score Top Affiliating Genes
1 pleomorphic xanthoastrocytoma 10.9
2 glioblastoma 10.5
3 glioma susceptibility 1 10.5
4 malignant astrocytoma 10.5
5 rare tumor 10.4
6 high grade glioma 10.3
7 anaplastic astrocytoma 10.3
8 retinoblastoma 10.1
9 aphasia 10.1
10 low grade glioma 10.1
11 benign ependymoma 10.1
12 ganglioglioma 10.1
13 cellular ependymoma 10.1
14 astroblastoma 10.1
15 neurofibromatosis 10.1
16 neurofibroma 10.1
17 anaplastic ganglioglioma 10.1
18 glioma 10.1
19 glial tumor 10.1
20 high-grade astrocytoma 10.1

Graphical network of the top 20 diseases related to Anaplastic Pleomorphic Xanthoastrocytoma:



Diseases related to Anaplastic Pleomorphic Xanthoastrocytoma

Symptoms & Phenotypes for Anaplastic Pleomorphic Xanthoastrocytoma

Drugs & Therapeutics for Anaplastic Pleomorphic Xanthoastrocytoma

Search Clinical Trials , NIH Clinical Center for Anaplastic Pleomorphic Xanthoastrocytoma

Genetic Tests for Anaplastic Pleomorphic Xanthoastrocytoma

Anatomical Context for Anaplastic Pleomorphic Xanthoastrocytoma

MalaCards organs/tissues related to Anaplastic Pleomorphic Xanthoastrocytoma:

40
Brain, Cerebellum

Publications for Anaplastic Pleomorphic Xanthoastrocytoma

Articles related to Anaplastic Pleomorphic Xanthoastrocytoma:

(show top 50) (show all 59)
# Title Authors PMID Year
1
Phase 1 study of pomalidomide in children with recurrent, refractory, and progressive central nervous system tumors: A Pediatric Brain Tumor Consortium trial. 61
33025730 2021
2
A case series of pediatric survivors of anaplastic pleomorphic xanthoastrocytoma. 61
33543147 2021
3
Conditional reprograming culture conditions facilitate growth of lower grade glioma models. 61
33258947 2020
4
An anaplastic pleomorphic xanthoastrocytoma with periventricular extension: An autopsy case report and review of the literature. 61
32578272 2020
5
Anaplastic Pleomorphic Xanthoastrocytoma: A Case Report and Literature Review. 61
33364820 2020
6
Challenges of targeting BRAF V600E mutations in adult primary brain tumor patients: a report of two cases. 61
31818130 2019
7
Disseminated anaplastic pleomorphic xanthoastrocytoma with posttreatment fat necrosis during combined BRAF and MEK inhibitors therapy. 61
31502413 2019
8
Histological and genetic analysis of anaplastic pleomorphic xanthoastrocytoma suspected of malignant progression over a 12-year clinical course. 61
31397529 2019
9
Spectroscopic measurement of 5-ALA-induced intracellular protoporphyrin IX in pediatric brain tumors. 61
31435824 2019
10
Anaplastic pleomorphic xanthoastrocytoma associated with an H3G34 mutation: a case report with review of literature. 61
31350684 2019
11
Evaluation of EZH2 expression, BRAF V600E mutation, and CDKN2A/B deletions in epithelioid glioblastoma and anaplastic pleomorphic xanthoastrocytoma. 61
31214915 2019
12
Urothelial carcinoma with an NRF1-BRAF rearrangement and response to targeted therapy. 61
31010895 2019
13
Retinal anaplastic pleomorphic xanthoastrocytoma unassociated with phakomatosis. 61
31317107 2019
14
Role of a Promoter Mutation in TERT in Malignant Transformation of Pleomorphic Xanthoastrocytoma. 61
30599247 2019
15
BRAF V600E-mutated central nervous system tumor with divergent morphological feature - Anaplastic pleomorphic xanthoastrocytoma-like and astroblastoma-like. 61
30557911 2019
16
A rare clinical presentation: a pleomorphic xanthoastrocytoma presenting with intracerebral haemorrhage and metastasizing vigorously-case report and review of the literature. 61
30182181 2019
17
Genome-wide DNA methylation profiling shows molecular heterogeneity of anaplastic pleomorphic xanthoastrocytoma. 61
30609203 2019
18
The genetic landscape of anaplastic pleomorphic xanthoastrocytoma. 61
30051528 2019
19
Anaplastic pleomorphic xanthoastrocytoma with leptomeningeal dissemination responsive to BRAF inhibition and bevacizumab. 61
30255633 2019
20
BRAF V600E, TERT, and IDH2 Mutations in Pleomorphic Xanthoastrocytoma: Observations from a Large Case-Series Study. 61
30240866 2018
21
Complete Remission of an Extracranially Disseminated Anaplastic Pleomorphic Xanthoastrocytoma With Everolimus: A Case Report and Literature Review. 61
30322731 2018
22
Clinico-Histomorphological and Immunohistochemical Profile of Anaplastic Pleomorphic Xanthoastrocytoma: Report of Five Cases and Review of Literature. 61
30774826 2018
23
Response to BRAF/MEK Inhibition After Progression With BRAF Inhibition in a Patient With Anaplastic Pleomorphic Xanthoastrocytoma. 61
30169370 2018
24
Sustained Response to Targeted Therapy in a Patient With Disseminated Anaplastic Pleomorphic Xanthoastrocytoma. 61
29200156 2018
25
MR Imaging Features of Anaplastic Pleomorphic Xanthoastrocytoma Mimicking High-Grade Astrocytoma. 61
29903923 2018
26
Intraventricular Anaplastic Pleomorphic Xanthoastrocytoma: Very Rare Localization and Early Recurrence of a Rare Tumor. 61
30042916 2018
27
Concurrent BRAF/MEK Inhibitors in BRAF V600-Mutant High-Grade Primary Brain Tumors. 61
29632053 2018
28
BRAF activating mutations involving the β3-αC loop in V600E-negative anaplastic pleomorphic xanthoastrocytoma. 61
29544532 2018
29
Multimodal molecular analysis of astroblastoma enables reclassification of most cases into more specific molecular entities. 61
28960623 2018
30
Recurrent copy number alterations in low-grade and anaplastic pleomorphic xanthoastrocytoma with and without BRAF V600E mutation. 61
28181325 2018
31
WHO 2016 Classification of gliomas. 61
28815663 2018
32
Anaplastic Pleomorphic Xanthoastrocytoma Presenting with Musical Hallucination. 61
30534452 2018
33
[The 2016 WHO classification of primary central nervous system tumors: a clinician's view]. 61
29927430 2018
34
Ganglioglioma Progression to Combined Anaplastic Ganglioglioma and Anaplastic Pleomorphic Xanthoastrocytoma. Case Report and Literature Review. 61
28939541 2017
35
Anaplastic Pleomorphic Xanthoastrocytoma in a Case of Neurofibromatosis Type 1: A Case Report. 61
28571159 2017
36
BRAF/MEK double blockade in refractory anaplastic pleomorphic xanthoastrocytoma. 61
28235815 2017
37
Dabrafenib in BRAFV600-mutated anaplastic pleomorphic xanthoastrocytoma. 61
27781490 2017
38
Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation. 61
27624885 2016
39
[Epilepsy-associated tumors of the central nervous system: Epilepsy surgery and oncological aspects]. 61
26676655 2016
40
Successful Treatment of a Progressive BRAF V600E-Mutated Anaplastic Pleomorphic Xanthoastrocytoma With Vemurafenib Monotherapy. 61
25092772 2016
41
Primary anaplastic pleomorphic xanthoastrocytoma in adults. Case report and review of literature. 61
27639203 2016
42
Anaplastic pleomorphic xanthoastrocytoma with spinal leptomeningeal spread at the time of diagnosis in an adult. 61
25934112 2015
43
KIAA1549:BRAF fusion gene in pediatric brain tumors of various histogenesis. 61
25382612 2015
44
DNA methylation alterations in grade II- and anaplastic pleomorphic xanthoastrocytoma. 61
24650279 2014
45
Primary multicentric anaplastic pleomorphic xanthoastrocytoma with atypical features. 61
23827171 2013
46
Clinical neuropathology practice news 2-2012: BRAF V600E testing. 61
22385786 2012
47
Establishment of a primary pleomorphic xanthoastrocytoma cell line: in vitro responsiveness to some chemotherapeutics. 61
21629132 2012
48
Anaplastic pleomorphic xanthoastrocytoma with a component of anaplastic astrocytoma presenting as skull base tumor followed by downward extracranial extension. Case report. 61
21206189 2010
49
Primary anaplastic pleomorphic xanthoastrocytoma with widespread neuroaxis dissemination at diagnosis--a pediatric case report and review of the literature. 61
19326050 2009
50
Images in neuro-oncology: anaplastic pleomorphic xanthoastrocytoma. 61
16850109 2006

Variations for Anaplastic Pleomorphic Xanthoastrocytoma

Expression for Anaplastic Pleomorphic Xanthoastrocytoma

Search GEO for disease gene expression data for Anaplastic Pleomorphic Xanthoastrocytoma.

Pathways for Anaplastic Pleomorphic Xanthoastrocytoma

GO Terms for Anaplastic Pleomorphic Xanthoastrocytoma

Sources for Anaplastic Pleomorphic Xanthoastrocytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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