MCID: ANC001
MIFTS: 50

Ancylostomiasis

Categories: Eye diseases, Gastrointestinal diseases, Infectious diseases, Rare diseases, Skin diseases

Aliases & Classifications for Ancylostomiasis

MalaCards integrated aliases for Ancylostomiasis:

Name: Ancylostomiasis 12 54 45 15 17 74
Hookworm Infections 56 74
Ancylostomiasis Due to Ancylostoma Duodenale 74
Ancylostoma Duodenale Infection 54
Hookworm Infection 54

Classifications:



External Ids:

Disease Ontology 12 DOID:12841
MeSH 45 D000724
NCIt 51 C35805
SNOMED-CT 69 63479002 85807000
ICD10 34 B76.0

Summaries for Ancylostomiasis

NIH Rare Diseases : 54 The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.Orpha Number: 78Disease definitionAnkylostomiasis is a hookworm infection caused primarily by the species Ancylostoma duodenale or Necator americanus, usually acquired through penetration of the skin, (often asymptomatic but that can also manifest with an allergic reaction at the site of skin penetration), followed by the migration of larva through the bloodstream to the lungs (causing asymptomatic pneumonitis, eosinophilia) and finally reaching and colonizing the small intestines where they cause blood extravasation leading to diarrhea, abdominal pain, and when untreated, melena, iron-deficiency anemia and protein malnutrition.Visit the Orphanet disease page for more resources.

MalaCards based summary : Ancylostomiasis, also known as hookworm infections, is related to parasitic helminthiasis infectious disease and ankylostomiasis, and has symptoms including anemia, abdominal pain and intestinal bleeding. An important gene associated with Ancylostomiasis is EGR3 (Early Growth Response 3), and among its related pathways/superpathways are NAD metabolism and NRF2 pathway. The drugs Albendazole and Iron have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and small intestine, and related phenotype is homeostasis/metabolism.

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves infection of skin, eyes, and viscera in humans by the parasitic nematodes Ancylostoma braziliense, Ancylostoma ceylanicum, Ancylostoma duodenale or Ancylostoma caninum. The larvae cause lesions on the skin at the site of penetration. The infection has symptom intestinal bleeding, has symptom abdominal pain, has symptom anemia, has symptom severe diarrhea and has symptom malnutrition.

Wikipedia : 77 Ancylostomiasis (also anchylostomiasis or ankylostomiasis) is a hookworm disease caused by infection... more...

Related Diseases for Ancylostomiasis

Diseases related to Ancylostomiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 63)
# Related Disease Score Top Affiliating Genes
1 parasitic helminthiasis infectious disease 29.9 EPGN MT-CO1 RNASE3
2 ankylostomiasis 12.0
3 necatoriasis 11.1
4 ascaris lumbricoides infection 10.4
5 ascaridiasis 10.4
6 deficiency anemia 10.3
7 myiasis 10.3 ALPP MT-CO1
8 lice infestation 10.3 ALPP MT-CO1
9 pthirus pubis infestation 10.2 ALPP MT-CO1
10 iron deficiency anemia 10.2
11 tick infestation 10.2 ALPL ALPP
12 phacolytic glaucoma 10.2 NR5A1 SERPINA1
13 hypophosphatasia 10.2 ALPL ALPP
14 schistosomiasis 10.2
15 hepatic tuberculosis 10.2 ALPP SERPINA1
16 hypophosphatasia, infantile 10.2 ALPL ALPP
17 parasitic ectoparasitic infectious disease 10.2 ALPP MT-CO1
18 paragonimiasis 10.1 MT-CO1 RNASE3
19 celiac disease 1 10.1
20 diarrhea 10.1
21 boutonneuse fever 10.1 CP SERPINA1
22 taeniasis 10.1
23 trichuriasis 10.1
24 fascioliasis 10.1 ALPP CP
25 diphyllobothriasis 10.1 MT-CO1 SERPINA1
26 urinary schistosomiasis 10.0
27 dyspepsia 10.0
28 holoprosencephaly 1 10.0 MT-CO1 SERPINA1
29 malaria 10.0
30 hepatitis 10.0
31 hepatitis b 10.0
32 salmonellosis 10.0
33 cysticercosis 10.0
34 filariasis 10.0
35 chagas disease 10.0
36 shigellosis 10.0
37 trichostrongylosis 10.0
38 hypogonadism 10.0
39 iron metabolism disease 10.0
40 hypogonadotropism 10.0
41 pellagra 10.0
42 dwarfism 10.0
43 asthma 9.9
44 mycobacterium tuberculosis 1 9.9
45 acute promyelocytic leukemia 9.9
46 chitotriosidase deficiency 9.9
47 graft-versus-host disease 9.9
48 leukemia 9.9
49 intestinal schistosomiasis 9.9
50 strongyloidiasis 9.9

Graphical network of the top 20 diseases related to Ancylostomiasis:



Diseases related to Ancylostomiasis

Symptoms & Phenotypes for Ancylostomiasis

Symptoms:

12
  • anemia
  • abdominal pain
  • intestinal bleeding
  • malnutrition
  • severe diarrhea

MGI Mouse Phenotypes related to Ancylostomiasis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.36 ALPI ALPL CP CYGB EGR3 EPGN

Drugs & Therapeutics for Ancylostomiasis

Drugs for Ancylostomiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 58)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Albendazole Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 54965-21-8 2082
2
Iron Approved, Experimental Phase 4,Phase 1,Not Applicable 7439-89-6, 15438-31-0 27284 23925
3
Pyrantel Approved, Vet_approved Phase 4 15686-83-6
4
Mebendazole Approved, Vet_approved Phase 4,Phase 3,Not Applicable 31431-39-7 4030
5
Sodium Citrate Approved, Investigational Phase 4,Phase 3,Not Applicable 68-04-2
6
Piperazine Approved, Vet_approved Phase 4,Phase 3 110-85-0 4837
7
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Not Applicable 77-92-9 311
8
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4,Not Applicable 68-26-8, 22737-96-8, 11103-57-4 9904001 445354
9 Oxantel Experimental Phase 4 36531-26-7
10 Antimitotic Agents Phase 4,Phase 3,Phase 2,Not Applicable
11 Antiprotozoal Agents Phase 4,Phase 2,Phase 3,Not Applicable
12 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Not Applicable
13 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Not Applicable
14 Anthelmintics Phase 4,Phase 3,Phase 2,Not Applicable
15 Piperazine citrate Phase 4,Phase 3
16 Peripheral Nervous System Agents Phase 4
17 DMP 777 Phase 4,Phase 3 157341-41-8
18 Pyrantel Pamoate Phase 4
19 Citrate Phase 4,Phase 3,Not Applicable
20 Neuromuscular Blocking Agents Phase 4
21 Neuromuscular Agents Phase 4
22
Oxantel pamoate Phase 4 68813-55-8 5281086
23 Neuromuscular Depolarizing Agents Phase 4
24 Vitamins Phase 4,Not Applicable
25 Protective Agents Phase 4,Not Applicable
26 Micronutrients Phase 4,Not Applicable
27 Nutrients Phase 4,Not Applicable
28 Retinol palmitate Phase 4,Not Applicable
29 Antioxidants Phase 4,Not Applicable
30 Trace Elements Phase 4,Not Applicable
31 retinol Phase 4,Not Applicable
32 Vaccines Phase 4,Phase 2,Phase 1,Not Applicable
33
Ivermectin Approved, Investigational, Vet_approved Phase 2, Phase 3,Not Applicable 70288-86-7 6474909
34
Vitamin C Approved, Nutraceutical Phase 3,Not Applicable 50-81-7 54670067 5785
35
Aluminum hydroxide Approved, Investigational Phase 2,Phase 1 21645-51-2
36
Oxfendazole Investigational, Vet_approved Phase 2 53716-50-0 40854
37 Cayenne Phase 2
38 Immunologic Factors Phase 2,Phase 1,Not Applicable
39 Pharmaceutical Solutions Phase 2,Phase 1,Not Applicable
40 Milbemycin Phase 2
41 Gastrointestinal Agents Phase 2,Phase 1
42 Anti-Ulcer Agents Phase 2,Phase 1
43 Antacids Phase 2,Phase 1
44 Adjuvants, Immunologic Phase 2,Phase 1
45
Imidazole Experimental, Investigational Phase 1 288-32-4 795
46 CPG-oligonucleotide Phase 1
47 Interferon-gamma Phase 1
48 interferons Phase 1
49 Interleukin-12 Phase 1
50 Monophosphoryl lipid A Phase 1

Interventional clinical trials:

(show top 50) (show all 64)
# Name Status NCT ID Phase Drugs
1 Triple Combinations Against Hookworm Infections in Lao Completed NCT03278431 Phase 4 Albendazole;Pyrantel Pamoate;Oxantel Pamoate;Mebendazole
2 Efficacy and Safety of a Multi-dose Regimen of Mebendazole Against Hookworm in Children Completed NCT03245398 Phase 4 Treatment with one of the two regimens of mebendazole
3 Impact of Alternative Treatment Strategies and Delivery Systems for Soil-transmitted Helminths in Kenya Completed NCT02397772 Phase 4 albendazole
4 Effect of Hookworm Elimination and Vitamin A Intervention on Iron Status of Preschool Children in Sichuan, China Completed NCT02675140 Phase 4 ZENTEL;ZENTEL and Vitamin A Soft Capsules
5 The Efficacy of Five Anthelmintic Regimes Against Trichuris Trichiura Infections in Schoolchildren in Jimma, Ethiopia Completed NCT01327469 Phase 4 Albendazole, 2 x 400mg;Albendazole 400mg;Mebendazole 500mg;Mebendazole 2 x 500mg;Pyrantel-oxantel + mebendazole
6 Monitoring the Efficacy of Anthelmintics for the Treatment of Soil Transmitted Helminths P2 Completed NCT01379326 Phase 4 Mebendazole
7 Efficacy of Albendazole to Treat Intestinal Helminths and Its Effect on Gut Microflora Completed NCT01192802 Phase 4 albendazole;albendazole;albendazole
8 The Effect of a Deworming Intervention to Improve Early Childhood Growth and Development in Resource-poor Areas Completed NCT01314937 Phase 4 Mebendazole
9 Mebendazole Study Against Hookworm Infections in Children and Adolescents in Ghana Withdrawn NCT03261596 Phase 4 Mebendazole
10 Comparative Efficacy of Different Mebendazole Polymorphs in the Treatment of Soil-transmitted Helminth Infections Completed NCT01350271 Phase 3 Mebendazole polymorph A and C 500 mg;Mebendazole polymorph C;Placebo
11 A Safety Study of Mebendazole in Children 2 to 10 Years of Age Completed NCT01173562 Phase 3 Mebendazole
12 Efficacy and Safety of IVM/ALB Co-administration Not yet recruiting NCT03527732 Phase 2, Phase 3 Albendazole;Albendazole and Ivermectin
13 Inoculating Celiac Disease Patients With the Human Hookworm Necator Americanus: Evaluating Immunity and Gluten-sensitivity Completed NCT00671138 Phase 2
14 Desensitising Celiac Disease Patients With the Human Hookworm Completed NCT01661933 Phase 1, Phase 2
15 Worms for Immune Regulation of Multiple Sclerosis Completed NCT01470521 Phase 2
16 Efficacy and Safety of Ascending Dosages of Moxidectin and Moxidectin-albendazole Against Trichuris Trichiura Completed NCT03501251 Phase 2 Moxidectin 8mg;Moxidectin 8 mg + albendazole 400 mg;Moxidectin 16 mg;Moxidectin 16 mg + albendazole 400 mg;Moxidectin 24 mg;Moxidectin 24 mg + albendazole 400 mg
17 Albendazole Dose Finding and Pharmacokinetics in Children and Adults Recruiting NCT03527745 Phase 2 Albendazole;Albendazole;Albendazole;Albendazole;Placebo
18 Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge Infection Recruiting NCT03172975 Phase 2 Albendazole
19 Study of the Efficacy of Oxfendazole Compared to Albendazole in the Treatment of Trichuris Trichiura Infection in Adults Not yet recruiting NCT02636803 Phase 2 oxfendazole;albendazole
20 Immunoregulation by Controlled Parasite Exposure in Multiple Sclerosis. Withdrawn NCT00630383 Phase 2
21 Study of Na-ASP-2 Human Hookworm Vaccine in Healthy Adults Without Evidence of Hookworm Infection Completed NCT00120081 Phase 1
22 Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With or Without Additional Adjuvant in Brazilian Adults Completed NCT01261130 Phase 1
23 Study of Na-APR-1 (M74)/Alhydrogel® Co-administered With Na-GST-1/Alhydrogel in Brazilian Adults Completed NCT02476773 Phase 1
24 Safety and Immunogenicity of Co-Administered Hookworm Vaccine Candidates Na-GST-1 and Na-APR-1 in Gabonese Adults Completed NCT02126462 Phase 1
25 Safety and Immunogenicity Study of Na-GST-1 With or Without CpG Completed NCT02143518 Phase 1
26 Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children Completed NCT02839161 Phase 1
27 Safety and Immunogenicity of the Na-APR-1 Hookworm Vaccine in Healthy Adults Completed NCT01717950 Phase 1
28 Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With Different Doses of a Novel Adjuvant Completed NCT01385189 Phase 1
29 Impact of Health Education on School Children Completed NCT01640626 Phase 1
30 Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae Recruiting NCT01940757 Phase 1
31 Na-GST-1/Alhydrogel With or Without CpG 10104 in Gabonese Adults Active, not recruiting NCT03373214 Phase 1
32 Hookworm Therapy for Coeliac Disease Active, not recruiting NCT02754609 Phase 1
33 Phase 1 Trial of Na-ASP-2 Hookworm Vaccine in Previously Infected Brazilian Adults Terminated NCT00473967 Phase 1
34 Does Treating Hookworm Improve Productivity of Small Subsistence Farmers Unknown status NCT02102321 Not Applicable albendazole;placebo
35 Prevalence of Hookworm Infection and Community Preparedness for Hookworm Vaccine Trials in Endemic Areas of Brazil Completed NCT00939198 Not Applicable
36 Randomised Controlled Clinical Trials of the Effect of Therapeutic Hookworm Infection in Allergic Rhinoconjunctivitis Completed NCT00232518 Not Applicable
37 Study to Test Whether Shoes Protect Children Against Hookworm Infection on Pemba Island, Zanzibar Completed NCT01869127 Not Applicable
38 Randomised Placebo Controlled Study of Effects of Therapeutic Hookworm Infection in Asthma Completed NCT00469989 Not Applicable
39 Repeated Controlled Human Hookworm Infection Completed NCT03257072 Not Applicable
40 Development of a Skin Test for the Na-ASP-2 Hookworm Antigen Completed NCT00603889 Not Applicable
41 Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma Completed NCT01163877 Not Applicable
42 Effectiveness of Combined Albendazole and Ivermectin Treatment for Intestinal Worm Infections Completed NCT00207753 Not Applicable albendazole vs. combined albendazole/ivermectin treatment
43 The Sero-Prevalence and Genetic Study for the Infectious Diseases and Metabolic Syndrome in Solomon Islands Completed NCT01080989 Not Applicable
44 Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children Completed NCT01658774 Not Applicable Albendazole
45 Education Intervention to Reduce Helminth Infections and Absenteeism in Grade 5 School-children Completed NCT01085799 Not Applicable
46 Spillover Effects of Water, Sanitation, and Hygiene Interventions on Child Health Completed NCT02396407 Not Applicable
47 Relative Efficacy of Two Regimens of Ante-helminthic Treatment Completed NCT00367627 Not Applicable Albendazole
48 Pulmonary Hypertension in Patients With Sickle Cell Disease in Nigeria Completed NCT00367523
49 Empiric Therapy of Helminth Co-infection to Reduce HIV-1 Disease Progression Completed NCT00507221 Not Applicable Albendazole;Praziquantel;Current standard of care in Kenya
50 Water Uptake for Health in Amhara Pilot Completed NCT02373657 Not Applicable

Search NIH Clinical Center for Ancylostomiasis

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: ancylostomiasis

Genetic Tests for Ancylostomiasis

Anatomical Context for Ancylostomiasis

MalaCards organs/tissues related to Ancylostomiasis:

42
Skin, Eye, Small Intestine, Lung, Colon, Testes, Liver

Publications for Ancylostomiasis

Articles related to Ancylostomiasis:

(show top 50) (show all 186)
# Title Authors Year
1
Correlation between hematological parameters and ancylostomiasis: A retrospective study. ( 30390342 )
2019
2
ANCYLOSTOMIASIS CAUSING UPPER GASTROINTESTINAL BLEEDING: REAL-TIME ENDOSCOPIC PICTURES. ( 30946305 )
2019
3
Modified Harada-Mori and simple wet mount to determine hookworm infections in Yo Island urban area, Songkhla, Southern Thailand. ( 31049017 )
2019
4
New insights into the kinetics and variability of egg excretion in controlled human hookworm infections. ( 31077279 )
2019
5
Efficacy and tolerability of triple drug therapy with albendazole, pyrantel pamoate, and oxantel pamoate compared with albendazole plus oxantel pamoate, pyrantel pamoate plus oxantel pamoate, and mebendazole plus pyrantel pamoate and oxantel pamoate against hookworm infections in school-aged children in Laos: a randomised, single-blind trial. ( 29673735 )
2018
6
Prevalence of intestinal parasitic infections and associated risk factors for hookworm infections among primary schoolchildren in rural areas of Nakhon Si Thammarat, southern Thailand. ( 30217180 )
2018
7
Efficacy and safety of ascending dosages of tribendimidine against hookworm infections in children: a randomized controlled trial. ( 30496350 )
2018
8
Hookworm infections among migrant workers in Malaysia: Molecular identification of Necator americanus and Ancylostoma duodenale. ( 28610937 )
2017
9
The diversity and impact of hookworm infections in wildlife. ( 28765810 )
2017
10
Spatial distribution and risk factors of Schistosoma haematobium and hookworm infections among schoolchildren in Kwale, Kenya. ( 28863133 )
2017
11
Evaluation of the utility of conventional polymerase chain reaction for detection and species differentiation in human hookworm infections. ( 29114490 )
2017
12
Profiling Nonrecipients of Mass Drug Administration for Schistosomiasis and Hookworm Infections: A Comprehensive Analysis of Praziquantel and Albendazole Coverage in Community-Directed Treatment in Uganda. ( 26409064 )
2016
13
Current status of human hookworm infections, ascariasis, trichuriasis, schistosomiasis mekongi and other trematodiases in Lao People's Democratic Republic. ( 24515942 )
2014
14
High prevalence of Ancylostoma ceylanicum hookworm infections in humans, Cambodia, 2012. ( 24865815 )
2014
15
Prednisolone and cyclosporine A: effects on an experimental model of ancylostomiasis. ( 23142084 )
2013
16
Prevalence of ancylostomiasis in people living in slum area, Philhousepet of Eluru, West Godavari District (Andhra Pradesh). ( 24431537 )
2013
17
Comparison of real-time PCR and Kato smear microscopy for the detection of hookworm infections in three consecutive faecal samples from schoolchildren in Ghana. ( 23426113 )
2013
18
Impact of Plasmodium falciparum and hookworm infections on the frequency of anaemia in pregnant women of rural communities in Enugu, South East Nigeria. ( 23503560 )
2013
19
Intestinal ancylostomiasis: an unusual histologic finding. ( 22084430 )
2012
20
In vivo endoscopic imaging of ancylostomiasis-induced gastrointestinal bleeding: clinical and biological profiles. ( 22869629 )
2012
21
Molecular identification of human hookworm infections in economically disadvantaged communities in Peninsular Malaysia. ( 22556084 )
2012
22
Rapid detection and identification of human hookworm infections through high resolution melting (HRM) analysis. ( 22844538 )
2012
23
Evidence of microbial translocation associated with perturbations in T cell and antigen-presenting cell homeostasis in hookworm infections. ( 23056659 )
2012
24
Trichuris and hookworm infections associated with anaemia during pregnancy. ( 21281406 )
2011
25
The immunology of human hookworm infections. ( 20626810 )
2010
26
PCR-based coprodiagnostic tools reveal dogs as reservoirs of zoonotic ancylostomiasis caused by Ancylostoma ceylanicum in temple communities in Bangkok. ( 18556131 )
2008
27
Malaria and hookworm infections in relation to haemoglobin and serum ferritin levels in pregnancy in Masindi district, western Uganda. ( 17996912 )
2008
28
FLOTAC: a new sensitive technique for the diagnosis of hookworm infections in humans. ( 18028969 )
2008
29
Hookworm infections in Singaporean soldiers after jungle training in Brunei Darussalam. ( 17919671 )
2007
30
Efficacy of mebendazole and albendazole for Ascaris lumbricoides and hookworm infections in an area with long time exposure for antihelminthes, Northwest Ethiopia. ( 18330331 )
2007
31
The impact of concurrent and treated Ancylostoma ceylanicum hookworm infections on the immunogenicity of a recombinant hookworm vaccine in hamsters. ( 16323144 )
2006
32
Distribution and clustering of Oesophagostomum bifurcum and hookworm infections in northern Ghana. ( 16388688 )
2006
33
Impact of repeated mass treatment on human Oesophagostomum and hookworm infections in northern Ghana. ( 17054758 )
2006
34
Liver phosphatases in mice treated with lead during murine ancylostomiasis. ( 15814320 )
2005
35
Anemia, malaria and hookworm infections in a Vietnamese ethnic minority. ( 16295531 )
2005
36
Hookworm infections in human and laboratory animals--differences and similarities in immune responses. ( 16913526 )
2005
37
The short-term impact of albendazole treatment on Oesophagostomum bifurcum and hookworm infections in northern Ghana. ( 15228719 )
2004
38
An epidemiological study of ancylostomiasis in a rural area of Kanpur district Uttar Pradesh, India. ( 15129854 )
2003
39
Random spatial distribution of Schistosoma mansoni and hookworm infections among school children within a single village. ( 14533674 )
2003
40
Effect of lead and ancylostomiasis on phosphatases of heart in Swiss albino mice. ( 12568465 )
2002
41
Reduction in the prevalence and intensity of hookworm infections after praziquantel treatment for schistosomiasis infection. ( 12062494 )
2002
42
Association between Schistosoma mansoni and hookworm infections among schoolchildren in Côte d'Ivoire. ( 12387908 )
2002
43
Hookworm infections of schoolchildren in southern Thailand. ( 12693578 )
2002
44
Epidemiology of Necator americanus hookworm infections in Xiulongkan Village, Hainan Province, China: high prevalence and intensity among middle-aged and elderly residents. ( 11534635 )
2001
45
Efficacy of DEC against Ascaris and hookworm infections in schoolchildren. ( 11555442 )
2001
46
Immune responses in hookworm infections. ( 11585781 )
2001
47
Epidemiology of human ancylostomiasis among rural villagers in Nanlin County (Zhongzhou Village), Anhui Province, China: II. Seroepidemiological studies of the age relationships of serum antibody levels and infection status. ( 11414422 )
2000
48
The epidemiology of human hookworm infections in the southern region of Mali. ( 10886798 )
2000
49
Epidemiology of human ancylostomiasis among rural villagers in Nanlin County (Zhongzhou village), Anhui Province, China: age-associated prevalence, intensity and hookworm species identification. ( 10928362 )
1999
50
Comparison of the efficacy of mebendazole, albendazole and pyrantel in treatment of human hookworm infections in the southern region of Mali, West Africa. ( 10450449 )
1999

Variations for Ancylostomiasis

Expression for Ancylostomiasis

Search GEO for disease gene expression data for Ancylostomiasis.

Pathways for Ancylostomiasis

GO Terms for Ancylostomiasis

Cellular components related to Ancylostomiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 ALPG ALPI ALPL CP EPGN RNASE3
2 anchored component of membrane GO:0031225 9.26 ALPG ALPI ALPL ALPP
3 glutamate-cysteine ligase complex GO:0017109 8.62 GCLC GCLM

Biological processes related to Ancylostomiasis according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.73 GCLC GCLM MT-CO1
2 dephosphorylation GO:0016311 9.73 ALPG ALPI ALPL ALPP
3 response to activity GO:0014823 9.58 GCLC GCLM
4 glutathione metabolic process GO:0006749 9.58 GCLC GCLM
5 negative regulation of extrinsic apoptotic signaling pathway GO:2001237 9.57 GCLC GCLM
6 response to oxidative stress GO:0006979 9.56 CYGB GCLC GCLM MT-CO1
7 apoptotic mitochondrial changes GO:0008637 9.55 GCLC GCLM
8 glutamate metabolic process GO:0006536 9.54 GCLC GCLM
9 regulation of blood vessel size GO:0050880 9.52 GCLC GCLM
10 glutathione biosynthetic process GO:0006750 9.51 GCLC GCLM
11 cellular response to hepatocyte growth factor stimulus GO:0035729 9.49 GCLC GCLM
12 cellular response to follicle-stimulating hormone stimulus GO:0071372 9.48 GCLC GCLM
13 regulation of mitochondrial depolarization GO:0051900 9.46 GCLC GCLM
14 cysteine metabolic process GO:0006534 9.4 GCLC GCLM
15 response to human chorionic gonadotropin GO:0044752 9.37 GCLC GCLM
16 cellular response to fibroblast growth factor stimulus GO:0044344 9.33 EGR3 GCLC GCLM
17 response to nitrosative stress GO:0051409 9.32 GCLC GCLM
18 cellular response to thyroxine stimulus GO:0097069 8.96 GCLC GCLM
19 negative regulation of hepatic stellate cell activation GO:2000490 8.62 CYGB GCLC

Molecular functions related to Ancylostomiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metal ion binding GO:0046872 9.97 ALPG ALPI ALPL ALPP CP CYGB
2 catalytic activity GO:0003824 9.56 ALPI ALPL ALPP GCLC
3 magnesium ion binding GO:0000287 9.54 ALPI ALPP GCLC
4 phosphatase activity GO:0016791 9.46 ALPG ALPI ALPL ALPP
5 glutamate-cysteine ligase activity GO:0004357 8.96 GCLC GCLM
6 alkaline phosphatase activity GO:0004035 8.92 ALPG ALPI ALPL ALPP

Sources for Ancylostomiasis

3 CDC
7 CNVD
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10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
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31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
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45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
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52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
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75 UMLS via Orphanet
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