MCID: ANC001
MIFTS: 48

Ancylostomiasis

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Ancylostomiasis

MalaCards integrated aliases for Ancylostomiasis:

Name: Ancylostomiasis 12 53 44 15 73
Hookworm Infections 55 73
Ancylostomiasis Due to Ancylostoma Duodenale 73
Ancylostoma Duodenale Infection 53
Hookworm Infection 53

Classifications:



External Ids:

Disease Ontology 12 DOID:12841
ICD10 33 B76.0
MeSH 44 D000724
NCIt 50 C35805
SNOMED-CT 68 63479002 85807000

Summaries for Ancylostomiasis

NIH Rare Diseases : 53 The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.Orpha Number: 78Disease definitionAnkylostomiasis is a hookworm infection caused primarily by the species Ancylostoma duodenale or Necator americanus, usually acquired through penetration of the skin, (often asymptomatic but that can also manifest with an allergic reaction at the site of skin penetration), followed by the migration of larva through the bloodstream to the lungs (causing asymptomatic pneumonitis, eosinophilia) and finally reaching and colonizing the small intestines where they cause blood extravasation leading to diarrhea, abdominal pain, and when untreated, melena, iron-deficiency anemia and protein malnutrition.Visit the Orphanet disease page for more resources.

MalaCards based summary : Ancylostomiasis, also known as hookworm infections, is related to taeniasis and iron metabolism disease, and has symptoms including intestinal bleeding, abdominal pain and anemia. An important gene associated with Ancylostomiasis is SLC25A46 (Solute Carrier Family 25 Member 46), and among its related pathways/superpathways are NRF2 pathway and Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling. The drugs Albendazole and Iron have been mentioned in the context of this disorder. Affiliated tissues include skin, small intestine and eye, and related phenotype is homeostasis/metabolism.

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves infection of skin, eyes, and viscera in humans by the parasitic nematodes Ancylostoma braziliense, Ancylostoma ceylanicum, Ancylostoma duodenale or Ancylostoma caninum. The larvae cause lesions on the skin at the site of penetration. The infection has symptom intestinal bleeding, has symptom abdominal pain, has symptom anemia, has symptom severe diarrhea and has symptom malnutrition.

Wikipedia : 76 Ancylostomiasis (also anchylostomiasis or ankylostomiasis) is a hookworm disease caused by infection... more...

Related Diseases for Ancylostomiasis

Diseases related to Ancylostomiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 66)
# Related Disease Score Top Affiliating Genes
1 taeniasis 30.6 CD40LG MT-CO1
2 iron metabolism disease 30.1 CP TF
3 ankylostomiasis 11.4
4 phacolytic glaucoma 10.5 NR5A1 SERPINA1
5 fascioliasis 10.5 CP MT-CO1
6 myasthenic syndrome, congenital, 10 10.5 CD40LG MT-CO1
7 cystic echinococcosis 10.5 CD40LG MT-CO1
8 boutonneuse fever 10.4 CP SERPINA1
9 diphyllobothriasis 10.4 MT-CO1 SERPINA1
10 holoprosencephaly 1 10.4 MT-CO1 SERPINA1
11 geniculate herpes zoster 10.4 CD40LG SERPINA1
12 parasitic ichthyosporea infectious disease 10.4 CD40LG SERPINA1
13 rhinosporidiosis 10.4 CD40LG SERPINA1
14 norwegian scabies 10.4 CD40LG MT-CO1
15 transient arthritis 10.4 CD40LG SERPINA1
16 plasma protein metabolism disease 10.4 CD40LG SERPINA1
17 hypochromic microcytic anemia 10.3 CP TF
18 granulosa cell tumor of the ovary 10.3 CP SERPINA1
19 yellow nail syndrome 10.3 CD40LG TF
20 paragonimiasis 10.3 MT-CO1 RNASE3
21 byssinosis 10.3 CD40LG SERPINA1
22 eales disease 10.3 CP TF
23 syphilis 10.2 CD40LG CP
24 chronic interstitial cystitis 10.2 CD40LG RNASE3
25 skeletal tuberculosis 10.2 CP SLC25A46
26 toxocariasis 10.2 CD40LG RNASE3
27 congenital disorder of glycosylation, type ii 10.2 SERPINA1 TF
28 vasomotor rhinitis 10.2 CD40LG RNASE3
29 metal metabolism disorder 10.2 CP TF
30 retinitis pigmentosa 7 10.2 SERPINA1 TF
31 dirofilariasis 10.2 CD40LG MT-CO1
32 henoch-schoenlein purpura 10.1 CD40LG RNASE3
33 hemosiderosis 10.1 CP TF
34 siderosis 10.1 SERPINA1 TF
35 schistosomiasis 10.1
36 conjunctival disease 10.0 CD40LG RNASE3
37 neuroretinitis 10.0 CD40LG RNASE3
38 capillariasis 10.0 CD40LG EPGN
39 trichostrongyloidiasis 10.0 CD40LG EPGN
40 aging 9.9
41 hepatitis 9.9
42 trichuriasis 9.9
43 peritonitis 9.9
44 epileptic encephalopathy, early infantile, 36 9.9 CP SERPINA1 TF
45 hemochromatosis, type 1 9.8 CP SERPINA1 TF
46 churg-strauss syndrome 9.8 CD40LG RNASE3
47 opportunistic mycosis 9.8 CD40LG HHAT
48 protein-energy malnutrition 9.8 CP TF
49 malaria 9.8
50 hepatitis b 9.8

Graphical network of the top 20 diseases related to Ancylostomiasis:



Diseases related to Ancylostomiasis

Symptoms & Phenotypes for Ancylostomiasis

Symptoms:

12
  • intestinal bleeding
  • abdominal pain
  • anemia
  • severe diarrhea
  • malnutrition

MGI Mouse Phenotypes related to Ancylostomiasis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.36 CD40LG CP CYGB EGR3 EPGN GCLC

Drugs & Therapeutics for Ancylostomiasis

Drugs for Ancylostomiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 53)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Albendazole Approved, Vet_approved Phase 4,Phase 2,Not Applicable 54965-21-8 2082
2
Iron Approved Phase 4,Phase 1,Not Applicable 7439-89-6 23925
3
Mebendazole Approved, Vet_approved Phase 4,Phase 3,Not Applicable 31431-39-7 4030
4
Piperazine Approved, Vet_approved Phase 4,Phase 3 110-85-0 4837
5
Pyrantel Approved, Vet_approved Phase 4 15686-83-6
6
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Not Applicable 77-92-9 311
7
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4,Not Applicable 11103-57-4, 68-26-8 445354
8 Anthelmintics Phase 4,Phase 3,Phase 2,Not Applicable
9 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Not Applicable
10 Antimitotic Agents Phase 4,Phase 3,Phase 2,Not Applicable
11 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Not Applicable
12 Antiprotozoal Agents Phase 4,Phase 2,Not Applicable
13 Neuromuscular Agents Phase 4
14 Neuromuscular Blocking Agents Phase 4
15 Neuromuscular Depolarizing Agents Phase 4
16 Oxantel Phase 4
17
Oxantel pamoate Phase 4 68813-55-8 5281086
18 Peripheral Nervous System Agents Phase 4
19 Piperazine citrate Phase 4,Phase 3
20 Pyrantel Pamoate Phase 4
21 Antioxidants Phase 4,Not Applicable
22 Micronutrients Phase 4,Not Applicable
23 Protective Agents Phase 4,Not Applicable
24 Retinol palmitate Phase 4,Not Applicable
25 Trace Elements Phase 4,Not Applicable
26 Vitamins Phase 4,Not Applicable
27 Vaccines Phase 4,Phase 2,Phase 1,Not Applicable
28 Citrate Nutraceutical Phase 4,Phase 3,Not Applicable
29 retinol Nutraceutical Phase 4,Not Applicable
30
Vitamin C Approved, Nutraceutical Phase 3,Not Applicable 50-81-7 5785 54670067
31
Aluminum hydroxide Approved, Investigational Phase 2,Phase 1 21645-51-2
32
Oxfendazole Investigational, Vet_approved Phase 2 53716-50-0 40854
33 Pharmaceutical Solutions Phase 2,Phase 1,Not Applicable
34 Adjuvants, Immunologic Phase 2,Phase 1
35 Antacids Phase 2,Phase 1
36 Anti-Ulcer Agents Phase 2,Phase 1
37 Gastrointestinal Agents Phase 2,Phase 1
38 Cayenne Nutraceutical Phase 2
39
Imidazole Experimental, Investigational Phase 1 288-32-4 795
40 CPG-oligonucleotide Phase 1
41 Interferon-gamma Phase 1
42 interferons Phase 1
43 Interleukin-12 Phase 1
44 Monophosphoryl lipid A Phase 1
45
Ivermectin Approved, Investigational, Vet_approved Not Applicable 70288-86-7 6474909
46
Praziquantel Approved, Investigational, Vet_approved Not Applicable 55268-74-1 4891
47
Menthol Approved Not Applicable 2216-51-5 16666
48
Diethylcarbamazine Approved, Investigational, Vet_approved ,Not Applicable 90-89-1 3052
49
Permethrin Approved, Investigational Not Applicable 52645-53-1 40326
50 Antibodies Not Applicable

Interventional clinical trials:

(show top 50) (show all 62)
# Name Status NCT ID Phase Drugs
1 Impact of Alternative Treatment Strategies and Delivery Systems for Soil-transmitted Helminths in Kenya Unknown status NCT02397772 Phase 4 albendazole
2 Triple Combinations Against Hookworm Infections in Lao Completed NCT03278431 Phase 4 Albendazole;Pyrantel Pamoate;Oxantel Pamoate;Mebendazole
3 Efficacy and Safety of a Multi-dose Regimen of Mebendazole Against Hookworm in Children Completed NCT03245398 Phase 4 Treatment with one of the two regimens of mebendazole
4 Effect of Hookworm Elimination and Vitamin A Intervention on Iron Status of Preschool Children in Sichuan, China Completed NCT02675140 Phase 4 ZENTEL;ZENTEL and Vitamin A Soft Capsules
5 The Efficacy of Five Anthelmintic Regimes Against Trichuris Trichiura Infections in Schoolchildren in Jimma, Ethiopia Completed NCT01327469 Phase 4 Albendazole, 2 x 400mg;Albendazole 400mg;Mebendazole 500mg;Mebendazole 2 x 500mg;Pyrantel-oxantel + mebendazole
6 Monitoring the Efficacy of Anthelmintics for the Treatment of Soil Transmitted Helminths P2 Completed NCT01379326 Phase 4 Mebendazole
7 Efficacy of Albendazole to Treat Intestinal Helminths and Its Effect on Gut Microflora Completed NCT01192802 Phase 4 albendazole;albendazole;albendazole
8 The Effect of a Deworming Intervention to Improve Early Childhood Growth and Development in Resource-poor Areas Completed NCT01314937 Phase 4 Mebendazole
9 Mebendazole Study Against Hookworm Infections in Children and Adolescents in Ghana Withdrawn NCT03261596 Phase 4 Mebendazole
10 Comparative Efficacy of Different Mebendazole Polymorphs in the Treatment of Soil-transmitted Helminth Infections Completed NCT01350271 Phase 3 Mebendazole polymorph A and C 500 mg;Mebendazole polymorph C;Placebo
11 A Safety Study of Mebendazole in Children 2 to 10 Years of Age Completed NCT01173562 Phase 3 Mebendazole
12 Efficacy and Safety of IVM/ALB Co-administration Not yet recruiting NCT03527732 Phase 2, Phase 3 Albendazole;Albendazole and Ivermectin
13 Inoculating Celiac Disease Patients With the Human Hookworm Necator Americanus: Evaluating Immunity and Gluten-sensitivity Completed NCT00671138 Phase 2
14 Desensitising Celiac Disease Patients With the Human Hookworm Completed NCT01661933 Phase 1, Phase 2
15 Worms for Immune Regulation of Multiple Sclerosis Completed NCT01470521 Phase 2
16 Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge Infection Recruiting NCT03172975 Phase 2 Albendazole
17 Albendazole Dose Finding and Pharmacokinetics in Children and Adults Not yet recruiting NCT03527745 Phase 2 Albendazole;Albendazole;Albendazole;Albendazole;Placebo
18 Study of the Efficacy of Oxfendazole Compared to Albendazole in the Treatment of Trichuris Trichiura Infection in Adults Not yet recruiting NCT02636803 Phase 2 oxfendazole;albendazole
19 Efficacy and Safety of Ascending Dosages of Moxidectin and Moxidectin-albendazole Against Trichuris Trichiura Not yet recruiting NCT03501251 Phase 2 Moxidectin 8mg;Moxidectin 8 mg + albendazole 400 mg;Moxidectin 16 mg;Moxidectin 16 mg + albendazole 400 mg;Moxidectin 24 mg;Moxidectin 24 mg + albendazole 400 mg
20 Immunoregulation by Controlled Parasite Exposure in Multiple Sclerosis. Withdrawn NCT00630383 Phase 2
21 Study of Na-ASP-2 Human Hookworm Vaccine in Healthy Adults Without Evidence of Hookworm Infection Completed NCT00120081 Phase 1
22 Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With or Without Additional Adjuvant in Brazilian Adults Completed NCT01261130 Phase 1
23 Study of Na-APR-1 (M74)/Alhydrogel® Co-administered With Na-GST-1/Alhydrogel in Brazilian Adults Completed NCT02476773 Phase 1
24 Safety and Immunogenicity of Co-Administered Hookworm Vaccine Candidates Na-GST-1 and Na-APR-1 in Gabonese Adults Completed NCT02126462 Phase 1
25 Safety and Immunogenicity Study of Na-GST-1 With or Without CpG Completed NCT02143518 Phase 1
26 Safety and Immunogenicity of the Na-APR-1 Hookworm Vaccine in Healthy Adults Completed NCT01717950 Phase 1
27 Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With Different Doses of a Novel Adjuvant Completed NCT01385189 Phase 1
28 Impact of Health Education on School Children Completed NCT01640626 Phase 1
29 Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae Recruiting NCT01940757 Phase 1
30 Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children Recruiting NCT02839161 Phase 1
31 Hookworm Therapy for Coeliac Disease Active, not recruiting NCT02754609 Phase 1
32 Na-GST-1/Alhydrogel With or Without CpG 10104 in Gabonese Adults Not yet recruiting NCT03373214 Phase 1
33 Phase 1 Trial of Na-ASP-2 Hookworm Vaccine in Previously Infected Brazilian Adults Terminated NCT00473967 Phase 1
34 Does Treating Hookworm Improve Productivity of Small Subsistence Farmers Unknown status NCT02102321 Not Applicable albendazole;placebo
35 Prevalence of Hookworm Infection and Community Preparedness for Hookworm Vaccine Trials in Endemic Areas of Brazil Completed NCT00939198 Not Applicable
36 Randomised Controlled Clinical Trials of the Effect of Therapeutic Hookworm Infection in Allergic Rhinoconjunctivitis Completed NCT00232518 Not Applicable
37 Study to Test Whether Shoes Protect Children Against Hookworm Infection on Pemba Island, Zanzibar Completed NCT01869127 Not Applicable
38 Randomised Placebo Controlled Study of Effects of Therapeutic Hookworm Infection in Asthma Completed NCT00469989 Not Applicable
39 Development of a Skin Test for the Na-ASP-2 Hookworm Antigen Completed NCT00603889 Not Applicable
40 Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma Completed NCT01163877 Not Applicable
41 Effectiveness of Combined Albendazole and Ivermectin Treatment for Intestinal Worm Infections Completed NCT00207753 Not Applicable albendazole vs. combined albendazole/ivermectin treatment
42 The Sero-Prevalence and Genetic Study for the Infectious Diseases and Metabolic Syndrome in Solomon Islands Completed NCT01080989 Not Applicable
43 Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children Completed NCT01658774 Not Applicable Albendazole
44 Education Intervention to Reduce Helminth Infections and Absenteeism in Grade 5 School-children Completed NCT01085799 Not Applicable
45 Spillover Effects of Water, Sanitation, and Hygiene Interventions on Child Health Completed NCT02396407 Not Applicable
46 Relative Efficacy of Two Regimens of Ante-helminthic Treatment Completed NCT00367627 Not Applicable Albendazole
47 Pulmonary Hypertension in Patients With Sickle Cell Disease in Nigeria Completed NCT00367523
48 Empiric Therapy of Helminth Co-infection to Reduce HIV-1 Disease Progression Completed NCT00507221 Not Applicable Albendazole;Praziquantel;Current standard of care in Kenya
49 Water Uptake for Health in Amhara Pilot Completed NCT02373657 Not Applicable
50 Taenia Solium Control Case Study in Zambia Completed NCT01368354 Not Applicable

Search NIH Clinical Center for Ancylostomiasis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: ancylostomiasis

Genetic Tests for Ancylostomiasis

Anatomical Context for Ancylostomiasis

MalaCards organs/tissues related to Ancylostomiasis:

41
Skin, Small Intestine, Eye, Lung, Colon, Testes, Liver

Publications for Ancylostomiasis

Articles related to Ancylostomiasis:

(show top 50) (show all 132)
# Title Authors Year
1
Helminthiasis: Hookworm Infection Remains a Public Health Problem in Dera District, South Gondar, Ethiopia. ( 26657490 )
2015
2
The effect of hookworm infection and urinary schistosomiasis on blood hemoglobin concentration of schoolchildren living in northern Mozambique. ( 24879000 )
2014
3
Current status of human hookworm infections, ascariasis, trichuriasis, schistosomiasis mekongi and other trematodiases in Lao People's Democratic Republic. ( 24515942 )
2014
4
Prevalence of ancylostomiasis in people living in slum area, Philhousepet of Eluru, West Godavari District (Andhra Pradesh). ( 24431537 )
2013
5
Prednisolone and cyclosporine A: effects on an experimental model of ancylostomiasis. ( 23142084 )
2013
6
In vivo endoscopic imaging of ancylostomiasis-induced gastrointestinal bleeding: clinical and biological profiles. ( 22869629 )
2012
7
Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection. ( 22329990 )
2012
8
Intestinal ancylostomiasis: an unusual histologic finding. ( 22084430 )
2012
9
Suppression of inflammatory immune responses in celiac disease by experimental hookworm infection. ( 21949691 )
2011
10
Developing vaccines to combat hookworm infection and intestinal schistosomiasis. ( 20948553 )
2010
11
Development of a model of hookworm infection exhibiting salient characteristics of human infection. ( 18541773 )
2008
12
PCR-based coprodiagnostic tools reveal dogs as reservoirs of zoonotic ancylostomiasis caused by Ancylostoma ceylanicum in temple communities in Bangkok. ( 18556131 )
2008
13
Early stage-specific immune responses in primary experimental human hookworm infection. ( 18848637 )
2008
14
Chitotriosidase deficiency is not associated with human hookworm infection in a Papua New Guinean population. ( 17765019 )
2007
15
X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection. ( 15713464 )
2005
16
Liver phosphatases in mice treated with lead during murine ancylostomiasis. ( 15814320 )
2005
17
An epidemiological study of ancylostomiasis in a rural area of Kanpur district Uttar Pradesh, India. ( 15129854 )
2003
18
Effect of lead and ancylostomiasis on phosphatases of heart in Swiss albino mice. ( 12568465 )
2002
19
Reduction in the prevalence and intensity of hookworm infections after praziquantel treatment for schistosomiasis infection. ( 12062494 )
2002
20
Epidemiology of human ancylostomiasis among rural villagers in Nanlin County (Zhongzhou Village), Anhui Province, China: II. Seroepidemiological studies of the age relationships of serum antibody levels and infection status. ( 11414422 )
2000
21
Patterns of concurrent hookworm infection and schistosomiasis in schoolchildren in Tanzania. ( 10696404 )
1999
22
Epidemiology of human ancylostomiasis among rural villagers in Nanlin County (Zhongzhou village), Anhui Province, China: age-associated prevalence, intensity and hookworm species identification. ( 10928362 )
1999
23
Cutaneous larva migrans and enteric hookworm infections. ( 8921039 )
1996
24
Ascariasis, hookworm infection and serum retinol amongst children in Nepal. ( 8090537 )
1994
25
Metabolic disposition of methyl [5-[[4-(2-pyridinyl)-1-piperazinyl] carbonyl]-1-H-benzimidazol-2-yl] carbamate in hamsters: a study to understand chemoprophylactic action against experimental Ancylostomiasis. ( 7959932 )
1994
26
Measurement of hookworm infection intensity and circulating levels of IgE and autoantibodies to IgE in atopics and nonatopics living in a parasitized community in Papua New Guinea. ( 7874320 )
1994
27
Does ascariasis, trichuriasis and hookworm infection predispose to non-specific abdominal symptoms among adults in endemic areas? ( 8009635 )
1994
28
Do ascariasis, trichuriasis and hookworm infections predispose to non-specific abdominal symptoms among adults in endemic areas? ( 8273160 )
1993
29
A comparative study on the efficacy of albendazole and mebendazole in the treatment of ascariasis, hookworm infection and trichuriasis. ( 7939948 )
1993
30
Biochemical analysis of jejunal brush border membrane of golden hamster: pathogenic modulations due to ancylostomiasis. ( 1592419 )
1992
31
Eosinophilia in murine ancylostomiasis. ( 1512453 )
1992
32
Some histopathological and histochemical aspects of human ancylostomiasis. ( 2033294 )
1991
33
Effects of improved water supply and sanitation on ascariasis, diarrhoea, dracunculiasis, hookworm infection, schistosomiasis, and trachoma. ( 1835675 )
1991
34
Hookworm infection and protein-energy malnutrition: transverse evidence from two Malaysian ecological groups. ( 2124397 )
1990
35
Prevalence of ascariasis and ancylostomiasis in families: a collaborative inquiry. ( 2785724 )
1989
36
LAPffler syndrome and ancylostomiasis brasiliensis. ( 3173840 )
1988
37
Antiepidemic measures against ancylostomiasis and their efficiency in our conditions. ( 3221092 )
1988
38
Cell mediated immunity during experimental ancylostomiasis: a review. ( 3323310 )
1987
39
Does ancylostomiasis favour the intensity of Schistosoma mansoni infection? ( 3111023 )
1986
40
Cell-mediated immune response in ancylostomiasis. ( 3487599 )
1986
41
Ovicidal effects of albendazole in human ascariasis, ancylostomiasis and trichuriasis. ( 4039128 )
1985
42
Treatment of ancylostomiasis and ascariasis with Albendazole. ( 6372715 )
1984
43
Correlation between density of infection and blood picture in ancylostomiasis. ( 6610716 )
1984
44
Experimental ancylostomiasis in chickens: effect of various dose of infective Ancylostoma caninum larvae on their migration and distribution. ( 6873246 )
1983
45
Transfer of delayed hypersensitivity through repeatedly sensitized peritoneal exudate cells during experimental ancylostomiasis in mice. ( 6862315 )
1983
46
Anaemia and gastro-intestinal function in ancylostomiasis. ( 7131345 )
1982
47
Larval recovery in tissues of thymectomized, bursectomized & splenectomized chickens vis-a-vis sham operated & controls during experimental ancylostomiasis. ( 7169233 )
1982
48
The effect of metrifonate on hookworm infections in Kenyan children treated for urinary schistosomiasis. A preliminary report. ( 6892236 )
1982
49
Delayed (cellular) hypersensitivity in mice during experimental ancylostomiasis. III. Effect of longer latent period for immobilisation of challenged larvae in the adoptively immunized host. ( 7252144 )
1981
50
The use of delipidized larval antigen in the diagnosis of ancylostomiasis by intradermal tests. ( 7299150 )
1981

Variations for Ancylostomiasis

Expression for Ancylostomiasis

Search GEO for disease gene expression data for Ancylostomiasis.

Pathways for Ancylostomiasis

Pathways related to Ancylostomiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.49 GCLC GCLM SERPINA1
2 10.64 GCLC GCLM
3 10.53 CP GCLC GCLM TF
4 10.13 GCLC GCLM

GO Terms for Ancylostomiasis

Cellular components related to Ancylostomiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glutamate-cysteine ligase complex GO:0017109 8.62 GCLC GCLM

Biological processes related to Ancylostomiasis according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.74 CP SERPINA1 TF
2 aging GO:0007568 9.72 GCLC GCLM MT-CO1
3 negative regulation of extrinsic apoptotic signaling pathway GO:2001237 9.56 GCLC GCLM
4 apoptotic mitochondrial changes GO:0008637 9.54 GCLC GCLM
5 regulation of blood vessel size GO:0050880 9.52 GCLC GCLM
6 glutamate metabolic process GO:0006536 9.51 GCLC GCLM
7 glutathione biosynthetic process GO:0006750 9.49 GCLC GCLM
8 cellular response to hepatocyte growth factor stimulus GO:0035729 9.48 GCLC GCLM
9 cellular response to follicle-stimulating hormone stimulus GO:0071372 9.46 GCLC GCLM
10 response to oxidative stress GO:0006979 9.46 CYGB GCLC GCLM MT-CO1
11 regulation of mitochondrial depolarization GO:0051900 9.43 GCLC GCLM
12 cellular response to fibroblast growth factor stimulus GO:0044344 9.43 EGR3 GCLC GCLM
13 cysteine metabolic process GO:0006534 9.4 GCLC GCLM
14 response to nitrosative stress GO:0051409 9.37 GCLC GCLM
15 response to human chorionic gonadotropin GO:0044752 9.32 GCLC GCLM
16 cellular response to thyroxine stimulus GO:0097069 8.96 GCLC GCLM
17 negative regulation of hepatic stellate cell activation GO:2000490 8.62 CYGB GCLC

Molecular functions related to Ancylostomiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glutamate-cysteine ligase activity GO:0004357 8.62 GCLC GCLM

Sources for Ancylostomiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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