MAIS
MCID: AND005
MIFTS: 20

Androgen Insensitivity Syndrome, Mild (MAIS)

Categories: Rare diseases

Aliases & Classifications for Androgen Insensitivity Syndrome, Mild

MalaCards integrated aliases for Androgen Insensitivity Syndrome, Mild:

Name: Androgen Insensitivity Syndrome, Mild 53 29
Syndrome, Insensitivity, Androgen, Mild 40
Mild Androgen Insensitivity Syndrome 53
Undervirilized Male Syndrome 53
Mais 53

Classifications:



Summaries for Androgen Insensitivity Syndrome, Mild

MalaCards based summary : Androgen Insensitivity Syndrome, Mild, also known as syndrome, insensitivity, androgen, mild, is related to may-thurner syndrome and macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss. The drugs Ciprofloxacin and Ethambutol have been mentioned in the context of this disorder.

Related Diseases for Androgen Insensitivity Syndrome, Mild

Diseases related to Androgen Insensitivity Syndrome, Mild via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 6553)
# Related Disease Score Top Affiliating Genes
1 may-thurner syndrome 12.6
2 macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss 12.2
3 myh9 related thrombocytopenia 11.8
4 mycobacterium avium complex infections 11.8
5 migraine with or without aura 1 11.2
6 alzheimer disease 11.2
7 stroke, ischemic 11.2
8 systemic lupus erythematosus 11.1
9 attention deficit-hyperactivity disorder 11.1
10 dementia 11.1
11 crohn's disease 11.1
12 prostate cancer 11.1
13 mccune-albright syndrome 11.1
14 myocardial infarction 11.1
15 herpes zoster 11.1
16 dementia, lewy body 11.1
17 celiac disease 1 11.1
18 respiratory failure 11.1
19 neuroblastoma 1 11.1
20 gastrointestinal stromal tumor 11.1
21 schizophrenia 11.1
22 myeloma, multiple 11.1
23 diabetes mellitus, insulin-dependent 11.1
24 essential tremor 11.1
25 chronic pain 11.1
26 autism spectrum disorder 11.1
27 fatty liver disease 11.1
28 encephalitis 11.1
29 lymphangioleiomyomatosis 11.1
30 endometriosis 11.1
31 gastric cancer 11.1
32 cervical cancer 11.1
33 ocular motor apraxia 11.1
34 spinal muscular atrophy 11.1
35 dermatitis 11.1
36 leukemia, acute lymphoblastic 11.0
37 chronic fatigue syndrome 11.0
38 myasthenia gravis 11.0
39 ovarian cancer 11.0
40 diarrhea 11.0
41 human immunodeficiency virus type 1 11.0
42 hypogonadotropic hypogonadism 11.0
43 sjogren syndrome 11.0
44 down syndrome 11.0
45 multiple sclerosis 11.0
46 pre-eclampsia 11.0
47 breast cancer 11.0
48 graves' disease 11.0
49 atrial fibrillation 11.0
50 amyotrophic lateral sclerosis 1 11.0

Graphical network of the top 20 diseases related to Androgen Insensitivity Syndrome, Mild:



Diseases related to Androgen Insensitivity Syndrome, Mild

Symptoms & Phenotypes for Androgen Insensitivity Syndrome, Mild

Drugs & Therapeutics for Androgen Insensitivity Syndrome, Mild

Drugs for Androgen Insensitivity Syndrome, Mild (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
2
Ethambutol Approved Phase 4 74-55-5 3279 14052
3
Clarithromycin Approved Phase 4 81103-11-9 84029
4
Rifampicin Approved Phase 4 13292-46-1 5381226 5458213
5 Cytochrome P-450 CYP3A Inducers Phase 4
6 Cytochrome P-450 CYP3A Inhibitors Phase 4
7 Cytochrome P-450 Enzyme Inhibitors Phase 4
8 Cytochrome P-450 Enzyme Inducers Phase 4
9 Anti-Infective Agents Phase 4
10 Anti-Bacterial Agents Phase 4
11 Antitubercular Agents Phase 4
12 Antibiotics, Antitubercular Phase 4
13 Nucleic Acid Synthesis Inhibitors Phase 4
14 Topoisomerase Inhibitors Phase 4
15 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
16 Vaccines Phase 4
17 Guar
18 insulin
19 Insulin, Globin Zinc
20 Soy Bean

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Treatment of Pulmonary Disease Caused by MAIS, M.Xenopi or M.Malmoense: A Comparison of Two Triple Drug Regimens and an Assessment of the Value of Immunotherapy With M.Vaccae Completed NCT00367913 Phase 4 Addition of clarithromycin to rifampicin and ethambutol;Addition of Ciprofloxacin to rifampicin and ethambutol
2 Plasma Glucose and Insulin Responses After Consumption of Breakfasts With Different Sources of Soluble Fiber in Type 2 Diabetes Patients: a Randomized Crossover Clinical Trial Completed NCT02204384
3 Mild Acute Ischemic Stroke With Large Vessel Occlusion (MIST WAVE) Completed NCT03731351
4 Acceptability of α-amylase Fortified Blended Foods Among Children 12-36 Months Old Children and Caregivers in Burkina Faso Completed NCT02192892
5 Iowa/Nucleus 10/10 mm and Nucleus Freedom Cochlear Implants Implanted Bilaterally in Children Ages 12-24 Months Completed NCT00594061
6 Epidemiology and Clinico-genetic Correlations of Auto-inflammatory Diseases Recruiting NCT03643809
7 Vertical Exposure to Zika Virus and Its Consequences for Child Neurodevelopment: Cohort Study in Fiocruz/IFF Recruiting NCT03255369

Search NIH Clinical Center for Androgen Insensitivity Syndrome, Mild

Genetic Tests for Androgen Insensitivity Syndrome, Mild

Genetic tests related to Androgen Insensitivity Syndrome, Mild:

# Genetic test Affiliating Genes
1 Androgen Insensitivity Syndrome, Mild 29

Anatomical Context for Androgen Insensitivity Syndrome, Mild

Publications for Androgen Insensitivity Syndrome, Mild

Articles related to Androgen Insensitivity Syndrome, Mild:

# Title Authors PMID Year
1
An androgen receptor mutation causing androgen resistance in undervirilized male syndrome. 38
7962294 1994
2
[Undervirilized male syndrome]. 38
7757783 1993

Variations for Androgen Insensitivity Syndrome, Mild

Expression for Androgen Insensitivity Syndrome, Mild

Search GEO for disease gene expression data for Androgen Insensitivity Syndrome, Mild.

Pathways for Androgen Insensitivity Syndrome, Mild

GO Terms for Androgen Insensitivity Syndrome, Mild

Sources for Androgen Insensitivity Syndrome, Mild

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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