ANIB1
MCID: ANR027
MIFTS: 21

Aneurysm, Intracranial Berry, 1 (ANIB1)

Categories: Cardiovascular diseases, Genetic diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Aneurysm, Intracranial Berry, 1

MalaCards integrated aliases for Aneurysm, Intracranial Berry, 1:

Name: Aneurysm, Intracranial Berry, 1 57 13 70
Aneurysmal Subarachnoid Hemorrhage, Familial 57
Anib1 57

Characteristics:

OMIM®:

57 (Updated 20-May-2021)
Inheritance:
autosomal dominant


HPO:

31
aneurysm, intracranial berry, 1:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM® 57 105800
OMIM Phenotypic Series 57 PS105800
MedGen 41 C1862932
SNOMED-CT via HPO 68 128608001 1386000 263681008
UMLS 70 C1862932

Summaries for Aneurysm, Intracranial Berry, 1

OMIM® : 57 Rupture of an intracranial aneurysm, an outpouching or sac-like widening of a cerebral artery, leads to a subarachnoid hemorrhage, a sudden-onset disease that can lead to severe disability and death. Several risk factors such as smoking, hypertension, and excessive alcohol intake are associated with subarachnoid hemorrhage (summary by Krischek and Inoue, 2006). (105800) (Updated 20-May-2021)

MalaCards based summary : Aneurysm, Intracranial Berry, 1, also known as aneurysmal subarachnoid hemorrhage, familial, is related to intracranial berry aneurysm and aneurysm. An important gene associated with Aneurysm, Intracranial Berry, 1 is ANIB1 (Aneurysm, Intracranial Berry 1). Related phenotypes are intracranial hemorrhage and dilatation of the cerebral artery

Related Diseases for Aneurysm, Intracranial Berry, 1

Graphical network of the top 20 diseases related to Aneurysm, Intracranial Berry, 1:



Diseases related to Aneurysm, Intracranial Berry, 1

Symptoms & Phenotypes for Aneurysm, Intracranial Berry, 1

Human phenotypes related to Aneurysm, Intracranial Berry, 1:

31
# Description HPO Frequency HPO Source Accession
1 intracranial hemorrhage 31 HP:0002170
2 dilatation of the cerebral artery 31 HP:0004944

Symptoms via clinical synopsis from OMIM®:

57 (Updated 20-May-2021)
Neuro:
intracranial hemorrhage
cerebral aneurysm, often multiple

Clinical features from OMIM®:

105800 (Updated 20-May-2021)

Drugs & Therapeutics for Aneurysm, Intracranial Berry, 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Non Invasive Measurements of Intracranial Pressure After Aneurysmal Subarachnoid Hemorrhage Unknown status NCT03040284

Search NIH Clinical Center for Aneurysm, Intracranial Berry, 1

Genetic Tests for Aneurysm, Intracranial Berry, 1

Anatomical Context for Aneurysm, Intracranial Berry, 1

Publications for Aneurysm, Intracranial Berry, 1

Articles related to Aneurysm, Intracranial Berry, 1:

(show all 35)
# Title Authors PMID Year
1
Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA. 57
22286173 2012
2
Genome-wide association study of intracranial aneurysm identifies three new risk loci. 57
20364137 2010
3
Age at intracranial aneurysm rupture among generations: Familial Intracranial Aneurysm Study. 57
19237697 2009
4
A haplotype spanning two genes, ELN and LIMK1, decreases their transcripts and confers susceptibility to intracranial aneurysms. 57
16611674 2006
5
The genetics of intracranial aneurysms. 57
16736093 2006
6
Confirmation of chromosome 7q11 locus for predisposition to intracranial aneurysm. 57
14605871 2004
7
Anticipation in familial intracranial aneurysms in consecutive generations. 57
14512962 2003
8
Association of positional and functional candidate genes FGF1, FBN2, and LOX on 5q31 with intracranial aneurysm. 57
12750963 2003
9
Genomewide-linkage and haplotype-association studies map intracranial aneurysm to chromosome 7q11. 57
11536080 2001
10
Risks and benefits of screening for intracranial aneurysms in first-degree relatives of patients with sporadic subarachnoid hemorrhage. 57
10536126 1999
11
Family history of subarachnoid hemorrhage and the incidence of asymptomatic, unruptured cerebral aneurysms. 57
10470812 1999
12
Familial intracranial aneurysms: recurrence risk and accidental aggregation study. 57
9398980 1997
13
Familial subarachnoid hemorrhage: distinctive features and patterns of inheritance. 57
8526466 1995
14
Familial cerebral aneurysms: a study of 13 families. 57
8559290 1995
15
Familial aneurysmal subarachnoid hemorrhage: a community-based study. 57
7666217 1995
16
Outcome in familial subarachnoid hemorrhage. 57
7762046 1995
17
On the inheritance of intracranial aneurysms. 57
8091449 1994
18
Familial aggregation of cervical artery dissection and cerebral aneurysm. 57
8042229 1994
19
Familial subarachnoid hemorrhage in east Finland, 1977-1990. 57
8264874 1993
20
Intracranial aneurysms: a report of a large pedigree. 57
6859129 1983
21
Familial intracranial aneurysm and infundibular widening. 57
6646412 1983
22
Familial incidence of ruptured intracranial aneurysms. Report of 12 cases. 57
697608 1978
23
Familial intracranial aneurysms and cerebral vascular anomalies. 57
845628 1977
24
Familial aneurysms and infundibular widening. 57
4673261 1972
25
Familial intracranial aneurysms. 57
4649154 1972
26
Familial occurrence of multiple intracranial aneurysms. Case report. 57
5069384 1972
27
[Familial cases of intracranial aneurysms. Review of the literature and case report]. 57
4643949 1972
28
Familial intracranial aneurysms. 57
5090946 1971
29
[Familial occurrence of congenital intracranial aneurysf associated with cystic degeneration of the kidneys]. 57
5576485 1971
30
The familial occurrence of intracranial aneurysms. 57
5461057 1970
31
The familial incidence of intracranial aneurysms. 57
5418178 1970
32
The familial occurrence of berry aneurysm. 57
5684401 1968
33
Familial intracranial aneurysms. 57
5921322 1966
34
Familial incidence of cerebral aneurysms. 57
5901575 1966
35
Familial cerebral aneurysms including one extracranial internal carotid aneurysm. 57
13840303 1960

Variations for Aneurysm, Intracranial Berry, 1

Expression for Aneurysm, Intracranial Berry, 1

Search GEO for disease gene expression data for Aneurysm, Intracranial Berry, 1.

Pathways for Aneurysm, Intracranial Berry, 1

GO Terms for Aneurysm, Intracranial Berry, 1

Sources for Aneurysm, Intracranial Berry, 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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