MCID: ANG003
MIFTS: 27

Angelucci's Syndrome

Categories: Eye diseases

Aliases & Classifications for Angelucci's Syndrome

MalaCards integrated aliases for Angelucci's Syndrome:

Name: Angelucci's Syndrome 12 15
Acute Atopic Conjunctivitis 12 71 32
Angelucci Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11203
ICD9CM 34 372.05
NCIt 49 C34353
SNOMED-CT 67 67678004
ICD10 32 H10.1
UMLS 71 C0001309

Summaries for Angelucci's Syndrome

MalaCards based summary : Angelucci's Syndrome, also known as acute atopic conjunctivitis, is related to poliomyelitis and macular holes. An important gene associated with Angelucci's Syndrome is EVC (EvC Ciliary Complex Subunit 1), and among its related pathways/superpathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Affiliated tissues include eye, bone and lung, and related phenotype is craniofacial.

Related Diseases for Angelucci's Syndrome

Diseases related to Angelucci's Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 250)
# Related Disease Score Top Affiliating Genes
1 poliomyelitis 10.2 IFNG EVC
2 macular holes 10.1 MIF CXCL8
3 primary peritoneal carcinoma 10.1 IFNG CXCL8
4 clonorchiasis 10.1 IFNG CXCL8
5 meconium aspiration syndrome 10.1 IFNG CXCL8
6 pleural tuberculosis 10.1 IFNG CXCL8
7 lepromatous leprosy 10.1 MIF IFNG
8 erythema multiforme 10.1 IFNG CXCL8
9 bacterial sepsis 10.1 MIF CXCL8
10 viral meningitis 10.1 IFNG CXCL8
11 myelitis 10.0 IL17A CXCL8
12 acute generalized exanthematous pustulosis 10.0 IL17A CXCL8
13 neurosyphilis 10.0 IL17A CXCL8
14 septic arthritis 10.0 IFNG CXCL8
15 transverse myelitis 10.0 IL17A CXCL8
16 mycetoma 10.0 IL17A CXCL8
17 pustulosis of palm and sole 10.0 IL17A CXCL8
18 chorioretinitis 10.0 IL17A IFNG
19 invasive aspergillosis 10.0 IFNG CXCL8
20 fungal meningitis 10.0 IL17A IFNG
21 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.0 IL17A IFNG
22 central nervous system vasculitis 10.0 IL17A IFNG
23 viral pneumonia 10.0 IL17A CXCL8
24 pleurisy 10.0 IFNG CXCL8
25 primary systemic mycosis 10.0 IL17A IFNG
26 cystic echinococcosis 10.0 IL17A IFNG
27 echinococcosis 10.0 IL17A IFNG
28 allergic conjunctivitis 10.0 IFNG CXCL8
29 streptococcus pneumonia 10.0 IL17A CXCL8
30 amebiasis 10.0 IL17A CXCL8
31 chronic inflammatory demyelinating polyradiculoneuropathy 10.0 IL17A IFNG
32 polyradiculoneuropathy 10.0 IL17A IFNG
33 hidradenitis 10.0 IL17A IFNG
34 radiculopathy 10.0 IL17A CXCL8
35 hidradenitis suppurativa 10.0 IL17A IFNG
36 cryptococcosis 10.0 IL17A IFNG
37 splenic disease 10.0 IL17A IFNG
38 mycoplasma pneumoniae pneumonia 10.0 IL17A IFNG
39 fasciitis 10.0 IFNG CXCL8
40 coccidiosis 10.0 IL17A IFNG
41 dermatitis herpetiformis 10.0 IL17A CXCL8
42 churg-strauss syndrome 10.0 IL17A CXCL8
43 oral candidiasis 10.0 IL17A CXCL8
44 rectal disease 10.0 IL17A CXCL8
45 autoimmune disease of endocrine system 9.9 IL17A IFNG
46 cutaneous lupus erythematosus 9.9 IL17A IFNG
47 lymph node disease 9.9 IL17A IFNG
48 common cold 9.9 IL17A CXCL8
49 respiratory allergy 9.9 IL17A CXCL8
50 dengue hemorrhagic fever 9.9 IFNG CXCL8

Graphical network of the top 20 diseases related to Angelucci's Syndrome:



Diseases related to Angelucci's Syndrome

Symptoms & Phenotypes for Angelucci's Syndrome

MGI Mouse Phenotypes related to Angelucci's Syndrome:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 8.92 EVC IFNG IL17A IL1B

Drugs & Therapeutics for Angelucci's Syndrome

Search Clinical Trials , NIH Clinical Center for Angelucci's Syndrome

Genetic Tests for Angelucci's Syndrome

Anatomical Context for Angelucci's Syndrome

MalaCards organs/tissues related to Angelucci's Syndrome:

40
Eye, Bone, Lung, T Cells, Lymph Node, Thyroid, Skin

Publications for Angelucci's Syndrome

Variations for Angelucci's Syndrome

Expression for Angelucci's Syndrome

Search GEO for disease gene expression data for Angelucci's Syndrome.

Pathways for Angelucci's Syndrome

Pathways related to Angelucci's Syndrome according to GeneCards Suite gene sharing:

(show all 36)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.33 MIF IL1B IL17A IFNG CXCL8
2
Show member pathways
13.08 IL1B IL17A IFNG CXCL8
3
Show member pathways
12.59 IL1B IL17A IFNG CXCL8
4
Show member pathways
12.36 IL1B IL17A IFNG
5
Show member pathways
12.35 IL1B IL17A IFNG
6
Show member pathways
12.34 IL1B IL17A IFNG
7 12.31 IL1B IL17A IFNG
8
Show member pathways
12 MIF IL1B IFNG CXCL8
9
Show member pathways
11.97 IL1B IL17A IFNG CXCL8
10
Show member pathways
11.96 IL1B IFNG CXCL8
11
Show member pathways
11.96 IL1B IL17A IFNG CXCL8
12
Show member pathways
11.85 IL1B IL17A IFNG
13 11.77 IL1B IL17A CXCL8
14 11.73 IL1B IFNG CXCL8
15 11.69 IL1B IFNG CXCL8
16
Show member pathways
11.62 IL1B IFNG
17 11.57 IL1B IFNG CXCL8
18 11.56 IL1B IL17A IFNG
19 11.54 MIF IL1B IFNG CXCL8
20 11.47 IL1B CXCL8
21 11.46 IL1B IL17A IFNG
22 11.42 IL1B CXCL8
23 11.4 IFNG CXCL8
24 11.34 IL1B CXCL8
25 11.33 IL1B IFNG
26 11.33 IL1B IFNG
27 11.29 IL1B IFNG
28 11.27 IFNG CXCL8
29 11.24 IL1B IFNG CXCL8
30 11.23 IL1B IL17A IFNG CXCL8
31 11.17 IL1B IFNG
32 11.17 IL1B IFNG
33 11.05 IL1B IFNG
34 10.97 IL1B IFNG
35 10.94 IL1B IL17A IFNG
36
Show member pathways
10.72 MIF IL1B IFNG CXCL8

GO Terms for Angelucci's Syndrome

Cellular components related to Angelucci's Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 MIF IL1B IL17A IFNG CXCL8
2 extracellular space GO:0005615 9.02 MIF IL1B IL17A IFNG CXCL8

Biological processes related to Angelucci's Syndrome according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.67 IL1B IL17A CXCL8
2 positive regulation of protein phosphorylation GO:0001934 9.61 MIF IL1B IFNG
3 immune response GO:0006955 9.56 IL1B IL17A IFNG CXCL8
4 positive regulation of phagocytosis GO:0050766 9.54 IL1B IFNG
5 interleukin-12-mediated signaling pathway GO:0035722 9.52 MIF IFNG
6 positive regulation of nitric oxide biosynthetic process GO:0045429 9.51 IL1B IFNG
7 positive regulation of interleukin-6 secretion GO:2000778 9.48 IL1B IL17A
8 positive regulation of osteoclast differentiation GO:0045672 9.46 IL17A IFNG
9 inflammatory response GO:0006954 9.46 MIF IL1B IL17A CXCL8
10 astrocyte activation GO:0048143 9.4 IL1B IFNG
11 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.37 IL1B IFNG
12 positive regulation of chemokine biosynthetic process GO:0045080 9.32 IL1B IFNG
13 positive regulation of interleukin-23 production GO:0032747 8.96 IL17A IFNG
14 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 8.62 IL1B IFNG

Molecular functions related to Angelucci's Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 MIF IL1B IL17A IFNG CXCL8

Sources for Angelucci's Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....