MCID: ANG012
MIFTS: 21

Angiodysplasia of Intestine

Categories: Cardiovascular diseases, Gastrointestinal diseases

Aliases & Classifications for Angiodysplasia of Intestine

MalaCards integrated aliases for Angiodysplasia of Intestine:

Name: Angiodysplasia of Intestine 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:10846
ICD9CM 34 569.84
SNOMED-CT 67 32868004
UMLS 71 C0267367

Summaries for Angiodysplasia of Intestine

MalaCards based summary : Angiodysplasia of Intestine is related to mixed epithelial stromal tumour and acetaminophen metabolism. An important gene associated with Angiodysplasia of Intestine is CYP1A2 (Cytochrome P450 Family 1 Subfamily A Member 2), and among its related pathways/superpathways are Metabolism and Drug metabolism - cytochrome P450.

Related Diseases for Angiodysplasia of Intestine

Diseases related to Angiodysplasia of Intestine via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 125)
# Related Disease Score Top Affiliating Genes
1 mixed epithelial stromal tumour 10.1 CYP3A4 CYP1A2
2 acetaminophen metabolism 10.0 CYP3A4 CYP1A2
3 pulmonary artery disease 9.9 CYP3A4 CYP2C9
4 angiodysplasia 9.9 ATP4A ATP12A
5 pancreatic vasoactive intestinal peptide producing tumor 9.9 ATP4A ATP12A
6 hemangioma of intra-abdominal structure 9.9 ATP4A ATP12A
7 displacement of cardia through esophageal hiatus 9.9 ATP4A ATP12A
8 gastric hemangioma 9.9 ATP4A ATP12A
9 acquired gastric outlet stenosis 9.9 ATP4A ATP12A
10 benzylpenicillin allergy 9.9 ATP4A ATP12A
11 median arcuate ligament syndrome 9.9 ATP4A ATP12A
12 granulomatous gastritis 9.9 ATP4A ATP12A
13 bacterial esophagitis 9.9 ATP4A ATP12A
14 lingual goiter 9.9 ATP4A ATP12A
15 cascade stomach 9.9 ATP4A ATP12A
16 gastrojejunal ulcer 9.9 ATP4A ATP12A
17 fungal esophagitis 9.9 ATP4A ATP12A
18 gastric gastrinoma 9.9 ATP4A ATP12A
19 fungal gastritis 9.9 ATP4A ATP12A
20 superior mesenteric artery syndrome 9.9 ATP4A ATP12A
21 cervix erosion 9.9 ATP4A ATP12A
22 pneumatosis cystoides intestinalis 9.9 ATP4A ATP12A
23 hepatocellular adenoma 9.9 CYP3A4 CYP1A2
24 esophagus sarcoma 9.9 ATP4A ATP12A
25 esophagus melanoma 9.9 ATP4A ATP12A
26 polyposis, skin pigmentation, alopecia, and fingernail changes 9.9 ATP4A ATP12A
27 necrotizing gastritis 9.9 ATP4A ATP12A
28 central nervous system origin vertigo 9.9 ATP4A ATP12A
29 chronic laryngitis 9.9 ATP4A ATP12A
30 laryngitis 9.9 ATP4A ATP12A
31 cefuroxime allergy 9.9 ATP4A ATP12A
32 gastroduodenitis 9.9 ATP4A ATP12A
33 duodenitis 9.9 ATP4A ATP12A
34 chronic intestinal vascular insufficiency 9.9 ATP4A ATP12A
35 peptic ulcer perforation 9.9 ATP4A ATP12A
36 rumination disorder 9.9 ATP4A ATP12A
37 blind loop syndrome 9.9 ATP4A ATP12A
38 crab allergy 9.9 ATP4A ATP12A
39 acute laryngitis 9.9 ATP4A ATP12A
40 duodenal gastrinoma 9.9 ATP4A ATP12A
41 esophageal tuberculosis 9.9 ATP4A ATP12A
42 gastric dilatation 9.8 ATP4A ATP12A
43 diclofenac allergy 9.8 ATP4A ATP12A
44 internal hemorrhoid 9.8 ATP4A ATP12A
45 hemorrhoid 9.8 ATP4A ATP12A
46 lymphocytic gastritis 9.8 ATP4A ATP12A
47 duodenal obstruction 9.8 ATP4A ATP12A
48 pancreatic gastrinoma 9.8 ATP4A ATP12A
49 functional diarrhea 9.8 ATP4A ATP12A
50 gastritis, familial giant hypertrophic 9.8 ATP4A ATP12A

Graphical network of the top 20 diseases related to Angiodysplasia of Intestine:



Diseases related to Angiodysplasia of Intestine

Symptoms & Phenotypes for Angiodysplasia of Intestine

Drugs & Therapeutics for Angiodysplasia of Intestine

Search Clinical Trials , NIH Clinical Center for Angiodysplasia of Intestine

Genetic Tests for Angiodysplasia of Intestine

Anatomical Context for Angiodysplasia of Intestine

Publications for Angiodysplasia of Intestine

Variations for Angiodysplasia of Intestine

Expression for Angiodysplasia of Intestine

Search GEO for disease gene expression data for Angiodysplasia of Intestine.

Pathways for Angiodysplasia of Intestine

Pathways related to Angiodysplasia of Intestine according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.66 CYP3A4 CYP2C9 CYP1A2 ATP4A ATP12A
2
Show member pathways
12.5 CYP3A4 CYP2C9 CYP1A2
3
Show member pathways
11.74 CYP3A4 CYP2C9 CYP1A2
4
Show member pathways
11.67 CYP3A4 CYP2C9
5
Show member pathways
11.66 CYP3A4 CYP2C9 CYP1A2
6
Show member pathways
11.57 CYP3A4 CYP1A2
7
Show member pathways
11.51 CYP3A4 CYP2C9 CYP1A2
8
Show member pathways
11.5 CYP3A4 CYP1A2
9
Show member pathways
11.42 CYP3A4 CYP2C9 CYP1A2
10
Show member pathways
11.4 CYP3A4 CYP1A2
11
Show member pathways
11.31 CYP3A4 CYP2C9 CYP1A2
12
Show member pathways
11.29 CYP3A4 CYP2C9
13 11.25 CYP3A4 CYP2C9 CYP1A2
14
Show member pathways
11.1 CYP3A4 CYP1A2
15
Show member pathways
11.09 CYP3A4 CYP2C9 CYP1A2
16 11.06 CYP3A4 CYP2C9
17 10.98 CYP3A4 CYP2C9 CYP1A2
18
Show member pathways
10.95 CYP3A4 CYP1A2
19 10.9 CYP3A4 CYP1A2
20
Show member pathways
10.88 CYP3A4 CYP2C9 CYP1A2
21 10.83 CYP3A4 CYP2C9
22
Show member pathways
10.71 CYP3A4 CYP1A2
23
Show member pathways
10.66 CYP3A4 CYP2C9 CYP1A2
24 10.18 CYP3A4 CYP2C9 CYP1A2

GO Terms for Angiodysplasia of Intestine

Cellular components related to Angiodysplasia of Intestine according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 organelle membrane GO:0031090 8.8 CYP3A4 CYP2C9 CYP1A2

Biological processes related to Angiodysplasia of Intestine according to GeneCards Suite gene sharing:

(show all 23)
# Name GO ID Score Top Affiliating Genes
1 lipid metabolic process GO:0006629 9.79 CYP1A2 CYP2C9 CYP3A4
2 steroid metabolic process GO:0008202 9.7 CYP1A2 CYP2C9 CYP3A4
3 cholesterol metabolic process GO:0008203 9.67 CYP3A4 CYP2C9 CYP1A2
4 xenobiotic metabolic process GO:0006805 9.65 CYP3A4 CYP2C9 CYP1A2
5 retinol metabolic process GO:0042572 9.61 CYP1A2 CYP3A4
6 potassium ion import across plasma membrane GO:1990573 9.6 ATP12A ATP4A
7 arachidonic acid metabolic process GO:0019369 9.59 CYP1A2 CYP2C9
8 epoxygenase P450 pathway GO:0019373 9.58 CYP1A2 CYP2C9
9 cellular sodium ion homeostasis GO:0006883 9.58 ATP12A ATP4A
10 exogenous drug catabolic process GO:0042738 9.58 CYP3A4 CYP2C9 CYP1A2
11 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.57 ATP12A ATP4A
12 cellular potassium ion homeostasis GO:0030007 9.56 ATP12A ATP4A
13 sodium ion export across plasma membrane GO:0036376 9.55 ATP12A ATP4A
14 omega-hydroxylase P450 pathway GO:0097267 9.54 CYP1A2 CYP2C9
15 drug metabolic process GO:0017144 9.54 CYP3A4 CYP2C9 CYP1A2
16 heterocycle metabolic process GO:0046483 9.51 CYP1A2 CYP3A4
17 long-chain fatty acid biosynthetic process GO:0042759 9.5 CYP3A4 CYP2C9 CYP1A2
18 steroid catabolic process GO:0006706 9.46 CYP3A4 CYP1A2
19 monocarboxylic acid metabolic process GO:0032787 9.43 CYP2C9 CYP1A2
20 estrogen metabolic process GO:0008210 9.43 CYP3A4 CYP2C9 CYP1A2
21 oxidative demethylation GO:0070989 9.33 CYP3A4 CYP2C9 CYP1A2
22 drug catabolic process GO:0042737 9.13 CYP3A4 CYP2C9 CYP1A2
23 monoterpenoid metabolic process GO:0016098 8.8 CYP3A4 CYP2C9 CYP1A2

Molecular functions related to Angiodysplasia of Intestine according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 metal ion binding GO:0046872 9.93 CYP3A4 CYP2C9 CYP1A2 ATP4A ATP12A
2 oxidoreductase activity GO:0016491 9.72 CYP3A4 CYP2C9 CYP1A2
3 heme binding GO:0020037 9.67 CYP3A4 CYP2C9 CYP1A2
4 iron ion binding GO:0005506 9.65 CYP3A4 CYP2C9 CYP1A2
5 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.58 CYP3A4 CYP2C9 CYP1A2
6 steroid hydroxylase activity GO:0008395 9.52 CYP3A4 CYP2C9
7 sodium:potassium-exchanging ATPase activity GO:0005391 9.51 ATP4A ATP12A
8 estrogen 16-alpha-hydroxylase activity GO:0101020 9.46 CYP3A4 CYP1A2
9 potassium-transporting ATPase activity GO:0008556 9.43 ATP4A ATP12A
10 monooxygenase activity GO:0004497 9.43 CYP3A4 CYP2C9 CYP1A2
11 estrogen 2-hydroxylase activity GO:0101021 9.37 CYP3A4 CYP1A2
12 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 9.33 CYP3A4 CYP2C9 CYP1A2
13 potassium:proton exchanging ATPase activity GO:0008900 9.32 ATP4A ATP12A
14 aromatase activity GO:0070330 9.13 CYP3A4 CYP2C9 CYP1A2
15 caffeine oxidase activity GO:0034875 8.8 CYP3A4 CYP2C9 CYP1A2

Sources for Angiodysplasia of Intestine

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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