MCID: ANG025
MIFTS: 30

Angioimmunoblastic Lymphadenopathy with Dysproteinemia

Categories: Immune diseases, Rare diseases

Aliases & Classifications for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

MalaCards integrated aliases for Angioimmunoblastic Lymphadenopathy with Dysproteinemia:

Name: Angioimmunoblastic Lymphadenopathy with Dysproteinemia 20 37
Angioimmunoblastic with Dysproteinemia Lymphadenopathy 20

Classifications:



Summaries for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

MalaCards based summary : Angioimmunoblastic Lymphadenopathy with Dysproteinemia, also known as angioimmunoblastic with dysproteinemia lymphadenopathy, is related to cytokine deficiency and food allergy. An important gene associated with Angioimmunoblastic Lymphadenopathy with Dysproteinemia is IL13 (Interleukin 13), and among its related pathways/superpathways are Allograft rejection and Th17 cell differentiation. Affiliated tissues include bone, lung and skin.

Related Diseases for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

Diseases related to Angioimmunoblastic Lymphadenopathy with Dysproteinemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 364)
# Related Disease Score Top Affiliating Genes
1 cytokine deficiency 30.7 IL5 IL13
2 food allergy 30.2 TNF IL5 IL13
3 rubella 30.2 TNF IL6 IL5
4 toxoplasmosis 30.2 TNF IL6 IL5
5 bronchitis 29.9 TNF IL6 IL5 IL13
6 angioimmunoblastic t-cell lymphoma 11.4
7 polyclonal hypergammaglobulinemia 10.6
8 hemolytic anemia 10.6
9 peripheral t-cell lymphoma 10.5
10 anemia, autoimmune hemolytic 10.4
11 exanthem 10.4
12 lymphoproliferative syndrome 10.4
13 pure red-cell aplasia 10.4
14 chromosomal triplication 10.4
15 kaposi sarcoma 10.3
16 human cytomegalovirus infection 10.3
17 b-cell lymphoma 10.3
18 splenomegaly 10.3
19 aztreonam allergy 10.3 IL5 IL13
20 cefaclor allergy 10.3 IL5 IL13
21 cefuroxime allergy 10.3 IL5 IL13
22 chromium allergic contact dermatitis 10.3 IL5 IL13
23 ceftriaxone allergy 10.3 IL5 IL13
24 respiratory syncytial virus infectious disease 10.3 IL5 IL13
25 loeffler syndrome 10.3 IL5 IL13
26 chronic asthma 10.3 IL5 IL13
27 orange allergy 10.3 IL5 IL13
28 loiasis 10.3 IL5 IL13
29 mikulicz disease 10.3 IL5 IL13
30 eosinophilic gastritis 10.3 IL5 IL13
31 nut allergy 10.3 IL5 IL13
32 trichinosis 10.3 IL5 IL13
33 kimura disease 10.2 IL5 IL13
34 timothy grass allergy 10.2 IL5 IL13
35 nickel allergic contact dermatitis 10.2 IL5 IL13
36 vernal keratoconjunctivitis 10.2 IL5 IL13
37 toxocariasis 10.2 IL5 IL13
38 mite infestation 10.2 IL5 IL13
39 paragonimiasis 10.2 IL5 IL13
40 intrinsic asthma 10.2 IL5 IL13
41 vasomotor rhinitis 10.2 IL5 IL13
42 chronic meningitis 10.2 IL5 IL13
43 angiostrongyliasis 10.2 IL5 IL13
44 elephantiasis 10.2 IL5 IL13
45 egg allergy 10.2 IL5 IL13
46 filarial elephantiasis 10.2 IL5 IL13
47 strongyloidiasis 10.2 IL5 IL13
48 legume allergy 10.2 IL5 IL13
49 fruit allergy 10.2 IL5 IL13
50 chronic rhinitis 10.2 IL5 IL13

Graphical network of the top 20 diseases related to Angioimmunoblastic Lymphadenopathy with Dysproteinemia:



Diseases related to Angioimmunoblastic Lymphadenopathy with Dysproteinemia

Symptoms & Phenotypes for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

Drugs & Therapeutics for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

Search Clinical Trials , NIH Clinical Center for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Stem-cell-based therapeutic approaches for Angioimmunoblastic Lymphadenopathy with Dysproteinemia:
Hematopoietic stem cells for treatment of hematologic malignancies
Embryonic/Adult Cultured Cells Related to Angioimmunoblastic Lymphadenopathy with Dysproteinemia:
Bone marrow-derived hematopoietic stem cells

Genetic Tests for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

Anatomical Context for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

MalaCards organs/tissues related to Angioimmunoblastic Lymphadenopathy with Dysproteinemia:

40
Bone, Lung, Skin, Bone Marrow, Lymph Node, B Cells, Eye

Publications for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

Articles related to Angioimmunoblastic Lymphadenopathy with Dysproteinemia:

(show top 50) (show all 134)
# Title Authors PMID Year
1
Angioimmunoblastic T-cell lymphoma with autoimmune thrombocytopenia: a report of two cases. 61
19442454 2010
2
Angioimmunoblastic lymphadenopathy with dysproteinemia: thoracic involvement. 61
15072329 2004
3
Clinical mimics of lymphoma. 61
15266094 2004
4
Angioimmunoblastic lymphadenopathy with dysproteinemia following doxycycline administration. 61
12729371 2003
5
Treatment of angioimmunoblastic lymphadenopathy with dysproteinemia-type T-cell lymphoma with fludarabine. 61
12624498 2003
6
The World Health Organization classification of malignant lymphoma: incidence and clinical prognosis in HTLV-1-endemic area of Fukuoka. 61
11940200 2002
7
Survival and clonal expansion of mutating "forbidden" (immunoglobulin receptor-deficient) epstein-barr virus-infected b cells in angioimmunoblastic t cell lymphoma. 61
11581315 2001
8
Cutaneous involvement by angioimmunoblastic T-cell lymphoma with remarkable heterogeneous Epstein-Barr virus expression. 61
11493382 2001
9
Analysis of T-cell subpopulations in T-cell non-Hodgkin's lymphoma of angioimmunoblastic lymphadenopathy with dysproteinemia type by single target gene amplification of T cell receptor- beta gene rearrangements. 61
11337383 2001
10
High-dose chemotherapy and APSCT as a potential cure for relapsing hemolysing AILD. 61
11226525 2001
11
Successful treatment of angioimmunoblastic lymphadenopathy with dysproteinemia-type T-cell lymphoma with fludarabine. 61
11408715 2001
12
Autoimmune hemolytic anemia in patients with non-Hodgkin's lymphoma: characteristics and significance. 61
11205465 2000
13
Cytoplasmic cytokines in lymphoproliferative disorders: multiple cytokine production in angioimmunoblastic lymphadenopathy with dysproteinemia. 61
10953975 2000
14
Successful treatment of angioimmunoblastic lymphadenopathy with dysproteinemia-type T-cell lymphoma by combined methotrexate and prednisone. 61
10942945 2000
15
Cutaneous involvement in patients with angioimmunoblastic lymphadenopathy with dysproteinemia: a clinical, immunohistological, and molecular analysis. 61
10890990 2000
16
Seropositive rheumatoid arthritis with dermatomyositis sine myositis, angioimmunoblastic lymphadenopathy with dysproteinemia-type T cell lymphoma, and B cell lymphoma of the oropharynx. 61
10782842 2000
17
A case of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) together with total atelectasis of a lung caused by lymphadenopathy and pleural effusion. 61
10736820 2000
18
Angioimmunoblastic T-cell lymphoma (AIL-TCL) following macrolide administration. 61
10800250 2000
19
Successful treatment of immunoblastic lymphadenopathy-like T-cell lymphoma with cyclosporin A. 61
10706464 1999
20
Successful treatment with fludarabine in two cases of angioimmunoblastic lymphadenopathy with dysproteinemia. 61
10492085 1999
21
The role of 2-chlorodeoxyadenosine in the treatment of patients with refractory angioimmunoblastic lymphadenopathy with dysproteinemia. 61
10027729 1999
22
Successful treatment of angioimmunoblastic lymphadenopathy with dysproteinemia by local irradiation. 61
9646314 1998
23
Development of Epstein-Barr virus-associated B cell lymphoma after intensive treatment of patients with angioimmunoblastic lymphadenopathy with dysproteinemia. 61
9650454 1998
24
Angioimmunoblastic lymphadenopathy with dysproteinemia: emphasis on pathogenesis and treatment. 61
9554450 1998
25
Systemic lupus erythematosus-associated lymphoproliferative disorder: report of a case and discussion in light of the literature. 61
9269836 1997
26
Angioimmunoblastic lymphadenopathy with disseminated human herpesvirus 6 infection in a patient with acute myeloblastic leukemia. 61
9177444 1997
27
Angioimmunoblastic lymphadenopathy with dysproteinemia--lack of a prognostic value of clear cell morphology. 61
9143398 1997
28
Characteristics of malignant lymphoma in eastern Taiwan: comparison between aborigines and nonaborigines. 61
9080755 1997
29
Lymph node pathology in patients with a clinical diagnosis of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD): an analysis of 37 cases. 61
9251843 1997
30
Cutaneous involvement in prelymphomatous angioimmunoblastic lymphadenopathy. 61
9039203 1997
31
Clonal identification of trisomies 3, 5 and X in angioimmunoblastic lymphadenopathy with dysproteinemia by fluorescence in situ hybridization. 61
9086442 1997
32
[Malignant lymphoma with epithelioid cells]. 61
9221215 1997
33
Treatment of angioimmunoblastic lymphadenopathy with dysproteinemia using 2-chlorodeoxyadenosine. 61
9003160 1996
34
Hematologic disorders associated with deletions of chromosome 20q: a clinicopathologic study of 107 patients. 61
8929482 1996
35
Successful treatment of angioimmunoblastic lymphadenopathy with dysproteinemia with fludarabine. 61
8822958 1996
36
CNS complications in a girl with angioimmunoblastic lymphadenopathy with dysproteinemia (AILD). 61
8892375 1996
37
AILD-like dysplasia transformed in AILD-type T cell lymphoma in an HTLV-1 carrier: usefulness of interferon-alpha. 61
8701708 1996
38
Angioimmunoblastic T-cell lymphoma (angioimmunoblastic lymphadenopathy with dysproteinemia [AILD]-type T-cell lymphoma) followed by Hodgkin's disease associated with Epstein-Barr virus. 61
8808302 1995
39
[Detection of trisomy 3 in angioimmunoblastic lymphadenopathy with dysproteinemia by fluorescence in situ hybridization]. 61
8706171 1995
40
Heterogeneity of Epstein-Barr virus infection in angioimmunoblastic lymphadenopathy type T-cell lymphoma. 61
7698734 1994
41
Detection of aberrant clones in nearly all cases of angioimmunoblastic lymphadenopathy with dysproteinemia-type T-cell lymphoma by combined interphase and metaphase cytogenetics. 61
7919378 1994
42
Angioimmunoblastic lymphadenopathy with dysproteinemia and dermal T-cell lymphoma. 61
8082083 1994
43
Lymphoproliferative disorders of the lung: histopathology, clinical manifestations, and imaging features. 61
8037014 1994
44
Pure red cell aplasia associated with angioimmunoblastic lymphadenopathy with dysproteinemia. 61
8172198 1994
45
Epstein-Barr-encoded RNA in situ hybridization: diagnostic applications. 61
8013952 1994
46
[Angioimmunoblastic lymphadenopathy with dysproteinemia and hypothyreosis]. 61
17972823 1994
47
[Angioimmunoblastic lymphadenopathy with dysproteinemia and sclerosing cholangitis]. 61
8125036 1994
48
Cytogenetic findings in peripheral T-cell lymphomas as a basis for distinguishing low-grade and high-grade lymphomas. 61
8286748 1994
49
Angioimmunoblastic lymphadenopathy with dysproteinemia. 61
8296199 1993
50
Detection of Epstein-Barr virus DNA and EBV-determined nuclear antigen in angioimmunoblastic lymphadenopathy with dysproteinemia type T cell lymphoma. 61
8183733 1993

Variations for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

Expression for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

Search GEO for disease gene expression data for Angioimmunoblastic Lymphadenopathy with Dysproteinemia.

Pathways for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

Pathways related to Angioimmunoblastic Lymphadenopathy with Dysproteinemia according to GeneCards Suite gene sharing:

(show all 25)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.59 TNF IL6 IL5 IL13
2
Show member pathways
12.32 TNF IL6 IL5 IL13
3
Show member pathways
12.17 IL6 IL5 IL13
4
Show member pathways
11.96 TNF IL6 IL5 IL13
5 11.95 TNF IL6 IL13
6
Show member pathways
11.94 TNF IL6 IL5 IL13
7 11.78 TNF IL6 IL5
8 11.76 TNF IL6 IL13
9 11.68 TNF IL6 IL5
10 11.58 IL6 IL5 IL13
11 11.54 TNF IL5 IL13
12 11.4 TNF IL6 IL5
13 11.28 TNF IL6
14 11.26 TNF IL6 IL5 IL13
15 11.23 TNF IL6 IL13
16 11.19 TNF IL6
17 11.16 TNF IL6
18 11.1 TNF IL6
19 11.01 IL5 IL13
20 10.93 TNF IL6
21 10.85 TNF IL6
22 10.76 TNF IL6 IL5 IL13
23 10.76 TNF IL6 IL5 IL13
24 10.51 IL6 IL5 IL13
25 10.39 TNF IL6 IL5 IL13

GO Terms for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

Biological processes related to Angioimmunoblastic Lymphadenopathy with Dysproteinemia according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.81 TNF IL6 IL5 IL13
2 inflammatory response GO:0006954 9.71 TNF IL6 IL5 IL13
3 positive regulation of DNA-binding transcription factor activity GO:0051091 9.63 TNF IL6 IL5
4 positive regulation of B cell proliferation GO:0030890 9.59 IL5 IL13
5 positive regulation of chemokine production GO:0032722 9.58 TNF IL6
6 positive regulation of interleukin-10 production GO:0032733 9.58 IL6 IL13
7 microglial cell activation GO:0001774 9.57 TNF IL13
8 negative regulation of neurogenesis GO:0050768 9.56 TNF IL6
9 cytokine-mediated signaling pathway GO:0019221 9.56 TNF IL6 IL5 IL13
10 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.55 TNF IL6
11 positive regulation of glial cell proliferation GO:0060252 9.54 TNF IL6
12 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.52 TNF IL6
13 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.5 TNF IL6 IL13
14 positive regulation of neuroinflammatory response GO:0150078 9.49 TNF IL6
15 positive regulation of podosome assembly GO:0071803 9.48 TNF IL5
16 negative regulation of lipid storage GO:0010888 9.43 TNF IL6
17 vascular endothelial growth factor production GO:0010573 9.37 TNF IL6
18 positive regulation of smooth muscle cell proliferation GO:0048661 9.33 TNF IL6 IL13
19 positive regulation of JAK-STAT cascade GO:0046427 9.13 TNF IL6 IL5
20 positive regulation of immunoglobulin production GO:0002639 8.8 IL6 IL5 IL13

Molecular functions related to Angioimmunoblastic Lymphadenopathy with Dysproteinemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.92 TNF IL6 IL5 IL13

Sources for Angioimmunoblastic Lymphadenopathy with Dysproteinemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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