MCID: ANG014
MIFTS: 27

Angiokeratoma of Fordyce

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Angiokeratoma of Fordyce

MalaCards integrated aliases for Angiokeratoma of Fordyce:

Name: Angiokeratoma of Fordyce 12 15 74
Fordyce-Type Angiokeratoma of Scrotum 12
Fordyce Angiokeratoma 12
Fordyce's Spot 12

Classifications:



External Ids:

Disease Ontology 12 DOID:664
NCIt 51 C7752
SNOMED-CT 69 6331000
UMLS 74 C0263639

Summaries for Angiokeratoma of Fordyce

MalaCards based summary : Angiokeratoma of Fordyce, also known as fordyce-type angiokeratoma of scrotum, is related to vulvar angiokeratoma and angiokeratoma. An important gene associated with Angiokeratoma of Fordyce is PROX1 (Prospero Homeobox 1), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Angiogenesis (CST). Affiliated tissues include skin, kidney and neutrophil, and related phenotypes are cardiovascular system and hematopoietic system

Related Diseases for Angiokeratoma of Fordyce

Diseases related to Angiokeratoma of Fordyce via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 vulvar angiokeratoma 11.4
2 angiokeratoma 10.8
3 varicocele 10.2
4 neutrophil migration 10.1
5 fabry disease 10.1
6 penile cancer 10.1
7 keratoacanthoma 10.1
8 papular xanthoma 10.1
9 end stage renal failure 9.9 ACE WT1
10 urinary system disease 9.8 ACE WT1
11 kaposiform hemangioendothelioma 9.8 PECAM1 PROX1
12 angiosarcoma 9.8 PECAM1 PROX1
13 membranous nephropathy 9.7 ACE PECAM1
14 chronic kidney failure 9.7 ACE WT1
15 hemangioma 9.7 PECAM1 PROX1
16 focal segmental glomerulosclerosis 9.6 ACE WT1

Graphical network of the top 20 diseases related to Angiokeratoma of Fordyce:



Diseases related to Angiokeratoma of Fordyce

Symptoms & Phenotypes for Angiokeratoma of Fordyce

MGI Mouse Phenotypes related to Angiokeratoma of Fordyce:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.71 ACE PECAM1 PROX1 WT1
2 hematopoietic system MP:0005397 9.67 ACE PECAM1 PROX1 WT1
3 immune system MP:0005387 9.62 ACE PECAM1 PROX1 WT1
4 liver/biliary system MP:0005370 9.56 ACE PECAM1 PROX1 WT1
5 muscle MP:0005369 9.33 PECAM1 PROX1 WT1
6 renal/urinary system MP:0005367 9.13 ACE PECAM1 WT1
7 respiratory system MP:0005388 8.8 PECAM1 PROX1 WT1

Drugs & Therapeutics for Angiokeratoma of Fordyce

Search Clinical Trials , NIH Clinical Center for Angiokeratoma of Fordyce

Genetic Tests for Angiokeratoma of Fordyce

Anatomical Context for Angiokeratoma of Fordyce

MalaCards organs/tissues related to Angiokeratoma of Fordyce:

42
Skin, Kidney, Neutrophil

Publications for Angiokeratoma of Fordyce

Articles related to Angiokeratoma of Fordyce:

(show all 24)
# Title Authors Year
1
Pulsed dye laser versus long pulsed Nd:YAG laser in the treatment of angiokeratoma of Fordyce: A randomized, comparative, observer-blinded study. ( 26371766 )
2016
2
Angiokeratoma of Fordyce response to long pulsed Nd:YAG laser treatment. ( 26531316 )
2016
3
Multiple giant angiokeratoma of Fordyce on the shaft of the penis masquerading as keratoacanthoma. ( 26312700 )
2015
4
Unilateral angiokeratoma of Fordyce. ( 22917529 )
2013
5
Giant angiokeratoma of Fordyce over the vulva in a middle-aged woman: case report and review of literature. ( 23723496 )
2013
6
A giant angiokeratoma of Fordyce: an uncommon cause of acute scrotum. ( 24051154 )
2013
7
Late-onset Fabry disease associated with angiokeratoma of Fordyce and multiple cherry angiomas. ( 21457158 )
2011
8
Angiokeratoma of Fordyce treated with 0.5% ethanolamine oleate or 0.25% sodium tetradecyl sulfate. ( 21053421 )
2010
9
Treatment of angiokeratoma of Fordyce with long-pulse neodymium-doped yttrium aluminium garnet laser. ( 19076189 )
2009
10
Report of two angiokeratoma of Fordyce cases treated with a 1064 nm long-pulsed Nd:YAG laser. ( 19439000 )
2009
11
Angiokeratoma of Fordyce simulating recurrent penile cancer. ( 17382178 )
2007
12
Naevus lipomatosus cutaneous superficialis of Hoffmann-Zurhelle with angiokeratoma of Fordyce. ( 16586009 )
2006
13
Treatment of angiokeratoma of Fordyce with pulsed dye laser. ( 16970695 )
2006
14
Rare case of recurrent angiokeratoma of Fordyce on penile shaft. ( 17070385 )
2006
15
Unilateral angiokeratoma of Fordyce. ( 17642671 )
2004
16
Papular xanthoma associated with angiokeratoma of Fordyce: considerations on the nosography of this rare non-Langerhans cell histiocytoxanthomatosis. ( 12592087 )
2003
17
Angiokeratoma of Fordyce as a cause of red scrotum. ( 11829180 )
2002
18
An exceptional localization of angiokeratoma of fordyce on the glans penis. ( 12218243 )
2002
19
Angiokeratoma of fordyce on unusual site. ( 20921672 )
1999
20
Congenital angiokeratoma of Fordyce. ( 9553928 )
1998
21
Angiokeratoma of Fordyce: a cause of scrotal bleeding. ( 8012789 )
1994
22
Angiokeratoma of Fordyce. ( 2407964 )
1990
23
Angiokeratoma of Fordyce: successful treatment with the argon laser. ( 6505104 )
1984
24
Hemangiomas of the scrotum (angiokeratoma of Fordyce?). ( 20262881 )
1947

Variations for Angiokeratoma of Fordyce

Expression for Angiokeratoma of Fordyce

Search GEO for disease gene expression data for Angiokeratoma of Fordyce.

Pathways for Angiokeratoma of Fordyce

Pathways related to Angiokeratoma of Fordyce according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.08 PROX1 WT1
2 10.57 PECAM1 PROX1

GO Terms for Angiokeratoma of Fordyce

Biological processes related to Angiokeratoma of Fordyce according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 kidney development GO:0001822 9.13 ACE PROX1 WT1
2 positive regulation of heart growth GO:0060421 8.62 PROX1 WT1

Molecular functions related to Angiokeratoma of Fordyce according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription regulatory region DNA binding GO:0044212 8.62 PROX1 WT1

Sources for Angiokeratoma of Fordyce

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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