Aliases & Classifications for Angiolipoma

MalaCards integrated aliases for Angiolipoma:

Name: Angiolipoma 12 77 45 15 17 74

Classifications:



External Ids:

Disease Ontology 12 DOID:3616
MeSH 45 D018206
NCIt 51 C3733
SNOMED-CT 69 73219006
UMLS 74 C0206632

Summaries for Angiolipoma

Disease Ontology : 12 A lipoma that is a painful subcutaneous nodule, having all other features of a typical lipoma.

MalaCards based summary : Angiolipoma is related to liposarcoma and abdominal chemodectomas with cutaneous angiolipomas. An important gene associated with Angiolipoma is ACTC1 (Actin Alpha Cardiac Muscle 1), and among its related pathways/superpathways are Cardiac conduction and Interleukin-4 and 13 signaling. The drugs Miconazole and Sirolimus have been mentioned in the context of this disorder. Affiliated tissues include breast, colon and spinal cord, and related phenotype is Reduced mammosphere formation.

Wikipedia : 77 Angiolipoma is a subcutaneous nodule with vascular structure, having all other features of a typical... more...

Related Diseases for Angiolipoma

Diseases related to Angiolipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 122)
# Related Disease Score Top Affiliating Genes
1 liposarcoma 30.3 DES VIM
2 abdominal chemodectomas with cutaneous angiolipomas 12.3
3 infiltrating angiolipoma 12.3
4 epidural spinal canal angiolipoma 12.1
5 chemodectoma, intraabdominal, with cutaneous angiolipomas 12.0
6 birt-hogg-dube syndrome 11.4
7 cobb syndrome 11.2
8 tendons, extensor, of fingers, anomalous insertion of 11.1
9 angiolipomatosis, familial 11.1
10 intussusception 10.2
11 lymphangiectasis 10.2 ACTC1 VIM
12 glomangiomyoma 10.2 ACTC1 VIM
13 lymphangioma 10.2 ACTC1 VIM
14 intravascular papillary endothelial hyperplasia 10.2 ACTC1 VIM
15 adenofibroma 10.2 ACTC1 VIM
16 chordoma 10.2 DES VIM
17 ovarian fibrothecoma 10.2 ACTC1 DES
18 angiocentric glioma 10.2 ACTC1 VIM
19 cutaneous leiomyosarcoma 10.2 ACTC1 DES
20 hemangioma 10.2
21 botryoid rhabdomyosarcoma 10.2 ACTC1 DES
22 glomangioma 10.2 ACTC1 DES
23 infantile digital fibromatosis 10.1 DES VIM
24 lymphangiomatosis 10.1 DES VIM
25 pulmonary vein stenosis 10.1 ACTC1 DES
26 primitive neuroectodermal tumor of the cervix uteri 10.1 DES VIM
27 dendritic cell tumor 10.1 ACTC1 VIM
28 epulis 10.1 DES VIM
29 ischemic fasciitis 10.1 ACTC1 DES
30 progressive nodular histiocytosis 10.1 ACTC1 F13A1
31 granulosa cell tumor of the ovary 10.1 ACTC1 VIM
32 biphasic synovial sarcoma 10.1 DES VIM
33 fasciitis 10.1 ACTC1 DES
34 polymorphous low-grade adenocarcinoma 10.1 ACTC1 VIM
35 syringoma 10.1 DES VIM
36 scleromyxedema 10.1 ACTC1 F13A1
37 chronic intestinal pseudoobstruction 10.1 ACTG2 DES
38 cystic nephroma 10.1 DES VIM
39 dedifferentiated liposarcoma 10.1 ACTC1 DES
40 pleomorphic liposarcoma 10.1 DES VIM
41 desmoplastic small round cell tumor 10.1 DES VIM
42 myoepithelioma 10.1 ACTC1 VIM
43 microcolon 10.1 ACTG2 DES
44 mesenchymal chondrosarcoma 10.1 DES VIM
45 extraskeletal ewing sarcoma 10.1 DES VIM
46 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.1
47 tuberous sclerosis 10.1
48 melanoma 10.1
49 intramuscular hemangioma 10.1
50 paraplegia 10.1

Graphical network of the top 20 diseases related to Angiolipoma:



Diseases related to Angiolipoma

Symptoms & Phenotypes for Angiolipoma

GenomeRNAi Phenotypes related to Angiolipoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 8.92 ACTG2 DES F13A1 VIM

Drugs & Therapeutics for Angiolipoma

Drugs for Angiolipoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Miconazole Approved, Investigational, Vet_approved Phase 1, Phase 2 22916-47-8 4189
2
Sirolimus Approved, Investigational Phase 1, Phase 2 53123-88-9 46835353 6436030 5284616
3
Everolimus Approved Phase 1, Phase 2 159351-69-6 6442177 70789204
4 Anti-Bacterial Agents Phase 1, Phase 2
5 Anti-Infective Agents Phase 1, Phase 2
6 Immunosuppressive Agents Phase 1, Phase 2
7 Immunologic Factors Phase 1, Phase 2
8 Antibiotics, Antitubercular Phase 1, Phase 2
9 Antifungal Agents Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis (TSC) and Sporadic Lymphangioleiomyomatosis (LAM) Completed NCT00792766 Phase 1, Phase 2 everolimus (RAD001)
2 Insight Into Subcutaneous Adipose Tissue Disorders Recruiting NCT02838277

Search NIH Clinical Center for Angiolipoma

Cochrane evidence based reviews: angiolipoma

Genetic Tests for Angiolipoma

Anatomical Context for Angiolipoma

MalaCards organs/tissues related to Angiolipoma:

42
Breast, Colon, Spinal Cord, Bone, Tongue, Skeletal Muscle, Thyroid

Publications for Angiolipoma

Articles related to Angiolipoma:

(show top 50) (show all 297)
# Title Authors Year
1
PET/CT and MR Features of Infiltrating Spinal Angiolipoma. ( 30516665 )
2019
2
Giant angiolipoma of the back complicated with ulceration and sepsis: unusual presentation of a rare benign tumour. ( 30602285 )
2019
3
Bronchial angiolipoma successfully treated by sleeve resection of the right bronchus intermedius: a case report. ( 30704440 )
2019
4
Solitary noninfiltrating angiolipoma on the finger, an unusual localization. ( 30865409 )
2019
5
Angiolipoma of the Orbit. ( 30908468 )
2019
6
Four cases of spinal epidural angiolipoma. ( 29133105 )
2018
7
Spinal angiolipoma mimicking a schwannoma: A case report. ( 29721357 )
2018
8
A Rare Case of Brain Angiolipoma Imitating Arteriovenous Malformation: Differential Diagnosis, Surgical Treatment, and Literature Review. ( 29614355 )
2018
9
Epidural angiolipoma: A rare cause of spinal cord compression. ( 29573600 )
2018
10
Consistent Involvement of Chromosome 13 in Angiolipoma. ( 29275363 )
2018
11
Sudden paraplegia due to spontaneous bleeding in a thoracic epidural angiolipoma and literature review. ( 29472020 )
2018
12
Infiltrating angiolipoma of the foot: magnetic resonance imaging features and review of the literature. ( 29322209 )
2018
13
Hemorrhagic Sudden Onset of Spinal Epidural Angiolipoma. ( 30057841 )
2018
14
Spinal extradural angiolipoma: a report of two cases and review of literature. ( 30069550 )
2018
15
68Ga-PSMA Uptake in Angiolipoma. ( 30153142 )
2018
16
Frequent low-level mutations of protein kinase D2 in angiolipoma. ( 28139834 )
2017
17
Spinal thoracic extradural angiolipoma manifesting as acute onset of paraparesis: Case report and review of literature. ( 28791193 )
2017
18
Massive noninfiltrating angiolipoma of the buccal mucosa: Report of an extremely rare case. ( 28479700 )
2017
19
Gastric Angiolipoma: A Rare Entity. ( 28557598 )
2017
20
A case report and review of thoracic spinal angiolipoma. ( 28680732 )
2017
21
Non-Infiltrating Angiolipoma of Floor of Mouth-A Rare Case Report and Literature Review. ( 28384985 )
2017
22
Angiolipoma: a rare esophageal submucosal tumor. ( 28237393 )
2017
23
Angiolipoma on the Lumbar Spine. ( 29017310 )
2017
24
Lumbar Spinal Angiolipoma with Expanding Left Neural Foramen Mimicking Lumbar Schwannoma; Case Report and Review of The Literature. ( 29151988 )
2017
25
Epidural spinal angiolipoma: a case series. ( 28320469 )
2017
26
Upper eyelid angiolipoma associated friction in the glide zone. ( 28580224 )
2017
27
Spinal angiolipoma: observations upon three cases. ( 28884558 )
2017
28
Management and Excision of a 15A cm Paratesticular Angiolipoma. ( 28856106 )
2017
29
Non Infiltrating Angiolipoma of the Palate in Geriatric Patient: A Case Report with Review of Literature. ( 27014643 )
2016
30
Infiltrating angiolipoma of the chest wall: a rare clinical entity. ( 26724328 )
2016
31
A giant infiltrating angiolipoma of the mediastinum: a case report. ( 27906066 )
2016
32
Cutaneous variant of intravascular large B-cell lymphoma in a Japanese patient: An occult lesion localized in a solitary angiolipoma. ( 27422850 )
2016
33
Giant angiolipoma of the arm in an elderly patient. ( 27241610 )
2016
34
Spinal extradural angiolipoma manifested after normal vaginal delivery. ( 26928853 )
2016
35
Percutaneous endoscopic removal of a lumbar epidural angiolipoma via interlaminar approach: a technical report. ( 27890757 )
2016
36
Angiolipoma of the Breast: Multi-modality Imaging Findings. ( 27509032 )
2016
37
Bronchoscopic resection of bronchial angiolipoma: A rare case report. ( 28101361 )
2016
38
Four cases of spinal epidural angiolipoma. ( 26778809 )
2016
39
Spinal epidural angiolipoma. ( 26944587 )
2016
40
Intraarticular Giant Size Angiolipoma of the Knee Causing Lateral Patellar Dislocation. ( 27994926 )
2016
41
Giant calvarial intraosseous angiolipoma: a case report and review of the literature. ( 27076621 )
2016
42
Intraosseous Angiolipoma of the Rib. ( 27011581 )
2015
43
Rare case of adult jejunojejunal intussusception secondary to angiolipoma. ( 25883255 )
2015
44
Preoperative Embolization of a Posterior Mediastinal Lipid-Poor Angiolipoma Mimicking a Paravertebral Nerve Sheath Tumor. ( 26234843 )
2015
45
Spinal cavernous extradural angiolipoma manifesting as a spontaneous spinal epidural hematoma in a child. ( 26065860 )
2015
46
Subcutaneous cavernous angiolipoma: a new soft-tissue entity. ( 26228827 )
2015
47
Spontaneous rectal passage of a colonic angiolipoma after colonoscopy with forceps biopsy. ( 25251570 )
2015
48
Management of infiltrating spinal epidural angiolipoma. ( 25864069 )
2015
49
Paratesticular liposarcoma and contralateral angiolipoma in a 60-year-old patient. ( 26438682 )
2015
50
Infiltrating angiolipoma of the lower lip: A case report and literature review. ( 25621058 )
2015

Variations for Angiolipoma

Expression for Angiolipoma

Search GEO for disease gene expression data for Angiolipoma.

Pathways for Angiolipoma

GO Terms for Angiolipoma

Cellular components related to Angiolipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell body GO:0044297 9.26 ACTC1 ACTG2
2 cytoskeleton GO:0005856 9.26 ACTC1 ACTG2 DES VIM
3 filopodium GO:0030175 9.16 ACTC1 ACTG2
4 blood microparticle GO:0072562 8.8 ACTC1 ACTG2 F13A1

Biological processes related to Angiolipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.43 ACTC1 ACTG2 VIM
2 muscle contraction GO:0006936 9.32 ACTG2 DES
3 intermediate filament organization GO:0045109 9.16 DES VIM
4 mesenchyme migration GO:0090131 8.96 ACTC1 ACTG2
5 muscle filament sliding GO:0030049 8.8 ACTC1 DES VIM

Molecular functions related to Angiolipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.62 DES VIM

Sources for Angiolipoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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