Aliases & Classifications for Angiolipoma

MalaCards integrated aliases for Angiolipoma:

Name: Angiolipoma 12 75 44 15 17 72

Classifications:



External Ids:

Disease Ontology 12 DOID:3616
MeSH 44 D018206
NCIt 50 C3733
SNOMED-CT 68 73219006
UMLS 72 C0206632

Summaries for Angiolipoma

Disease Ontology : 12 A lipoma that is a painful subcutaneous nodule, having all other features of a typical lipoma.

MalaCards based summary : Angiolipoma is related to angiomyolipoma and liposarcoma. An important gene associated with Angiolipoma is ACTC1 (Actin Alpha Cardiac Muscle 1), and among its related pathways/superpathways are Cardiac conduction and Interleukin-4 and 13 signaling. The drugs Sirolimus and Everolimus have been mentioned in the context of this disorder. Affiliated tissues include breast, colon and spinal cord, and related phenotype is Reduced mammosphere formation.

Wikipedia : 75 Angiolipoma is a subcutaneous nodule with vascular structure, having all other features of a typical... more...

Related Diseases for Angiolipoma

Diseases related to Angiolipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 188)
# Related Disease Score Top Affiliating Genes
1 angiomyolipoma 30.8 DES ACTC1
2 liposarcoma 30.6 VIM DES
3 dedifferentiated liposarcoma 30.2 DES ACTC1
4 spindle cell lipoma 30.0 VIM DES ACTC1
5 neurilemmoma 30.0 VIM DES
6 leiomyoma 29.6 VIM DES ACTC1
7 spindle cell sarcoma 29.5 VIM DES ACTC1
8 gastrointestinal stromal tumor 29.5 VIM DES ACTC1
9 abdominal chemodectomas with cutaneous angiolipomas 12.5
10 infiltrating angiolipoma 12.5
11 chemodectoma, intraabdominal, with cutaneous angiolipomas 12.3
12 epidural spinal canal angiolipoma 12.3
13 angiolipomatosis, familial 11.6
14 birt-hogg-dube syndrome 11.5
15 cobb syndrome 11.4
16 cowden syndrome 1 11.2
17 tendons, extensor, of fingers, anomalous insertion of 11.2
18 lipomatosis, multiple 10.7
19 pleomorphic lipoma 10.7
20 rare tumor 10.4
21 hemangioma 10.4
22 paraplegia 10.4
23 tuberous sclerosis 10.4
24 back pain 10.4
25 ovarian fibrothecoma 10.3 DES ACTC1
26 cutaneous leiomyosarcoma 10.3 DES ACTC1
27 botryoid rhabdomyosarcoma 10.3 DES ACTC1
28 glomangioma 10.3 DES ACTC1
29 intussusception 10.3
30 progressive nodular histiocytosis 10.3 F13A1 ACTC1
31 pulmonary vein stenosis 10.3 DES ACTC1
32 scleromyxedema 10.3 F13A1 ACTC1
33 mesenchymal cell neoplasm 10.3
34 myofibroma 10.3 F13A1 DES
35 ischemic fasciitis 10.3 DES ACTC1
36 fasciitis 10.3 DES ACTC1
37 chronic intestinal pseudoobstruction 10.2 DES ACTG2
38 spastic paraparesis 10.2
39 microcolon 10.2 DES ACTG2
40 lymphangiectasis 10.2 VIM ACTC1
41 chordoma 10.2 VIM DES
42 lymphangioma 10.2 VIM ACTC1
43 glomangiomyoma 10.2 VIM ACTC1
44 intravascular papillary endothelial hyperplasia 10.2 VIM ACTC1
45 infantile digital fibromatosis 10.2 VIM DES
46 kaposi sarcoma 10.2
47 neurofibromatosis, type iv, of riccardi 10.2
48 arteriovenous malformation 10.2
49 lipomatosis 10.2
50 intramuscular hemangioma 10.2

Graphical network of the top 20 diseases related to Angiolipoma:



Diseases related to Angiolipoma

Symptoms & Phenotypes for Angiolipoma

GenomeRNAi Phenotypes related to Angiolipoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 8.92 ACTG2 DES F13A1 VIM

Drugs & Therapeutics for Angiolipoma

Drugs for Angiolipoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sirolimus Approved, Investigational Phase 1, Phase 2 53123-88-9 6436030 5284616 46835353
2
Everolimus Approved Phase 1, Phase 2 159351-69-6 6442177 70789204
3
Miconazole Approved, Investigational, Vet_approved Phase 1, Phase 2 22916-47-8 4189
4 Antifungal Agents Phase 1, Phase 2
5 Anti-Bacterial Agents Phase 1, Phase 2
6 Antibiotics, Antitubercular Phase 1, Phase 2
7 Anti-Infective Agents Phase 1, Phase 2
8 Immunosuppressive Agents Phase 1, Phase 2
9 Immunologic Factors Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis Complex and Sporadic Lymphangioleiomyomatosis Completed NCT00792766 Phase 1, Phase 2 everolimus (RAD001)
2 Renal Tumors Classification, Biology, and Banking Study Suspended NCT00898365

Search NIH Clinical Center for Angiolipoma

Cochrane evidence based reviews: angiolipoma

Genetic Tests for Angiolipoma

Anatomical Context for Angiolipoma

MalaCards organs/tissues related to Angiolipoma:

41
Breast, Colon, Spinal Cord, Bone, Kidney, Salivary Gland, Skeletal Muscle

Publications for Angiolipoma

Articles related to Angiolipoma:

(show top 50) (show all 457)
# Title Authors PMID Year
1
Microsurgical treatment for spinal epidural angiolipomas. 38
31309454 2019
2
Spinal angiolipoma: Presentation of two cases and review of the literature for the years 2012-2017. 38
31186156 2019
3
Upper gastrointestinal tract obstruction secondary to transpyloric prolapse of a gastric angiolipoma. 38
30955837 2019
4
PET/CT and MR Features of Infiltrating Spinal Angiolipoma. 38
30516665 2019
5
Spinal angiolipomas in pregnancy: Natural history and surgical treatment. 38
30684928 2019
6
Multiple gastric angiolipomas: A case report. 38
30968044 2019
7
Giant angiolipoma of the back complicated with ulceration and sepsis: unusual presentation of a rare benign tumour. 38
30602285 2019
8
Angiolipoma of the Orbit. 38
30908468 2019
9
Spinal angiolipoma. 38
28884558 2019
10
Solitary noninfiltrating angiolipoma on the finger, an unusual localization. 38
30865409 2019
11
A Paratesticular Angiolipoma: A Case Report of a Rare Benign Scrotal Mass and Review of Literature. 38
31321115 2019
12
Bronchial angiolipoma successfully treated by sleeve resection of the right bronchus intermedius: a case report. 38
30704440 2019
13
Management of Dumbbell and Paraspinal Tumors of the Thoracic Spine Using a Single-stage Posterolateral Approach: Case Series. 38
30406971 2018
14
68Ga-PSMA Uptake in Angiolipoma. 38
30153142 2018
15
Infiltrating angiolipoma of the foot: magnetic resonance imaging features and review of the literature. 38
29322209 2018
16
A Rare Case of Brain Angiolipoma Imitating Arteriovenous Malformation: Differential Diagnosis, Surgical Treatment, and Literature Review. 38
29614355 2018
17
Spinal extradural angiolipoma: a report of two cases and review of literature. 38
30069550 2018
18
Hyperechoic breast images: all that glitters is not gold! 38
29476429 2018
19
Sudden paraplegia due to spontaneous bleeding in a thoracic epidural angiolipoma and literature review. 38
29472020 2018
20
Four cases of spinal epidural angiolipoma. 38
29133105 2018
21
Consistent Involvement of Chromosome 13 in Angiolipoma. 38
29275363 2018
22
Spinal angiolipoma mimicking a schwannoma: A case report. 38
29721357 2018
23
Lipomas of cervical area - clinical and pathological considerations. 38
30173259 2018
24
An intraspinal extradural lipoma with spinal epidural lipomatosis: A case report and a review of literature. 38
30488010 2018
25
Epidural angiolipoma: A rare cause of spinal cord compression. 38
29573600 2018
26
Hemorrhagic Sudden Onset of Spinal Epidural Angiolipoma. 38
30057841 2018
27
Management and Excision of a 15 cm Paratesticular Angiolipoma. 38
28856106 2017
28
Rare cause of colonic intussusception in an adult. 38
28918406 2017
29
Angiolipoma on the Lumbar Spine. 38
29017310 2017
30
Angiolipoma: a rare esophageal submucosal tumor. 38
28237393 2017
31
Adrenal Mass: Unusual Presentation and Outcome. 38
29200669 2017
32
Gastric Angiolipoma: A Rare Entity. 38
28557598 2017
33
Spinal angiolipomas: A puzzling case and review of a rare entity. 38
28694590 2017
34
Frequent low-level mutations of protein kinase D2 in angiolipoma. 38
28139834 2017
35
Epidural spinal angiolipoma: a case series. 38
28320469 2017
36
Percutaneous Endoscopic Removal of a Lumbar Epidural Angiolipoma via Interlaminar Approach: A Technical Report. 38
27890757 2017
37
Cutaneous variant of intravascular large B-cell lymphoma in a Japanese patient: An occult lesion localized in a solitary angiolipoma. 38
27422850 2017
38
Non-Infiltrating Angiolipoma of Floor of Mouth-A Rare Case Report and Literature Review. 38
28384985 2017
39
Imaging review of lipomatous musculoskeletal lesions. 38
28474576 2017
40
Lumbar Spinal Angiolipoma with Expanding Left Neural Foramen Mimicking Lumbar Schwannoma; Case Report and Review of The Literature. 38
29151988 2017
41
Massive noninfiltrating angiolipoma of the buccal mucosa: Report of an extremely rare case. 38
28479700 2017
42
Spinal thoracic extradural angiolipoma manifesting as acute onset of paraparesis: Case report and review of literature. 38
28791193 2017
43
[Spinal epidural angiolipoma: a rare etiology of medullary compression]. 38
28533832 2017
44
Upper eyelid angiolipoma associated friction in the glide zone. 38
28580224 2017
45
A case report and review of thoracic spinal angiolipoma. 38
28680732 2017
46
Bronchoscopic resection of bronchial angiolipoma: A rare case report. 38
28101361 2016
47
A giant infiltrating angiolipoma of the mediastinum: a case report. 38
27906066 2016
48
Fat-containing soft-tissue masses in children. 38
27866258 2016
49
[Klippel-Feil syndrome with tracheoesophageal fistula, bifid thumb and cerebral angiolipoma.] 38
27869419 2016
50
Intraarticular Giant Size Angiolipoma of the Knee Causing Lateral Patellar Dislocation. 38
27994926 2016

Variations for Angiolipoma

Expression for Angiolipoma

Search GEO for disease gene expression data for Angiolipoma.

Pathways for Angiolipoma

GO Terms for Angiolipoma

Cellular components related to Angiolipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell body GO:0044297 9.26 ACTG2 ACTC1
2 cytoskeleton GO:0005856 9.26 VIM DES ACTG2 ACTC1
3 filopodium GO:0030175 9.16 ACTG2 ACTC1
4 blood microparticle GO:0072562 8.8 F13A1 ACTG2 ACTC1

Biological processes related to Angiolipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.43 VIM ACTG2 ACTC1
2 muscle contraction GO:0006936 9.32 DES ACTG2
3 intermediate filament organization GO:0045109 9.16 VIM DES
4 mesenchyme migration GO:0090131 8.96 ACTG2 ACTC1
5 muscle filament sliding GO:0030049 8.8 VIM DES ACTC1

Molecular functions related to Angiolipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.62 VIM DES

Sources for Angiolipoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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