Aliases & Classifications for Angiolipoma

MalaCards integrated aliases for Angiolipoma:

Name: Angiolipoma 12 74 43 15 17 71

Classifications:



External Ids:

Disease Ontology 12 DOID:3616
MeSH 43 D018206
NCIt 49 C3733
SNOMED-CT 67 73219006
UMLS 71 C0206632

Summaries for Angiolipoma

Disease Ontology : 12 A lipoma that is a painful subcutaneous nodule, having all other features of a typical lipoma.

MalaCards based summary : Angiolipoma is related to infiltrating angiolipoma and birt-hogg-dube syndrome. An important gene associated with Angiolipoma is ACTC1 (Actin Alpha Cardiac Muscle 1), and among its related pathways/superpathways is Striated Muscle Contraction. The drugs Sirolimus and Everolimus have been mentioned in the context of this disorder. Affiliated tissues include breast, bone and skin, and related phenotypes are Reduced mammosphere formation and cellular

Wikipedia : 74 Angiolipoma is a subcutaneous nodule with vascular structure, having all other features of a typical... more...

Related Diseases for Angiolipoma

Diseases related to Angiolipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 319)
# Related Disease Score Top Affiliating Genes
1 infiltrating angiolipoma 33.2 MLANA MDM2 CD34
2 birt-hogg-dube syndrome 32.0 FLCN FH CLEC2A
3 rare tumor 31.3 DES ACTC1
4 pleomorphic lipoma 31.0 MDM2 CD34
5 hemangioma 30.7 PECAM1 CD34 ACTC1
6 angiomyolipoma 30.3 VIM MLANA DES ACTC1
7 kidney angiomyolipoma 30.3 MLANA FLCN
8 lipomatosis, multiple 30.2 MLANA MDM2 DES CD34
9 tuberous sclerosis 30.2 VIM MLANA FLCN
10 mesenchymal cell neoplasm 30.2 PECAM1 MLANA CD34
11 neurilemmoma 30.1 VIM DES CD34 ACTC1
12 liposarcoma 29.9 VIM MDM2 DES CD34
13 intussusception 29.9 PECAM1 CD34
14 gastrointestinal stromal tumor 29.8 VIM DES CD34 ACTC1
15 dedifferentiated liposarcoma 29.7 MDM2 DES ACTC1
16 spindle cell lipoma 29.4 VIM MDM2 DES CD34 ACTC1
17 leiomyoma 29.4 VIM FH DES CD34 ACTC1
18 connective tissue benign neoplasm 29.1 PECAM1 MDM2 FLCN CD34
19 spindle cell sarcoma 29.0 VIM MDM2 DES CD34 ACTC1
20 fibroma 29.0 VIM PECAM1 F13A1 DES CD34 ACTC1
21 renal cell carcinoma, nonpapillary 28.9 VIM PECAM1 FLCN FH ACTC1
22 angiosarcoma 28.6 VIM PECAM1 MLANA MDM2 CD34
23 abdominal chemodectomas with cutaneous angiolipomas 12.5
24 chemodectoma, intraabdominal, with cutaneous angiolipomas 12.3
25 epidural spinal canal angiolipoma 12.3
26 angiolipomatosis, familial 11.6
27 cobb syndrome 11.4
28 cowden syndrome 1 11.2
29 tendons, extensor, of fingers, anomalous insertion of 11.2
30 ovarian fibrothecoma 10.5 DES ACTC1
31 progressive nodular histiocytosis 10.5 F13A1 ACTC1
32 scleromyxedema 10.5 F13A1 ACTC1
33 lymphangiectasis 10.5 VIM ACTC1
34 intravascular papillary endothelial hyperplasia 10.5 VIM ACTC1
35 infantile digital fibromatosis 10.5 VIM DES
36 primitive neuroectodermal tumor of the cervix uteri 10.4 VIM DES
37 lymphangiomatosis 10.4 VIM DES
38 syringocystadenoma papilliferum 10.4 DES ACTC1
39 tumor of meninges 10.4 VIM F13A1
40 botryoid rhabdomyosarcoma 10.4 DES ACTC1
41 ewing sarcoma of bone 10.4 VIM DES
42 congenital epulis 10.4 VIM DES
43 angiocentric glioma 10.4 VIM ACTC1
44 epulis 10.4 VIM DES
45 vulvar sarcoma 10.4 CD34 ACTC1
46 spindle cell thymoma 10.4 DES CD34
47 pyogenic granuloma 10.4 CD34 ACTC1
48 cervical polyp 10.4 DES CD34
49 paraplegia 10.4
50 multicentric reticulohistiocytosis 10.4 VIM F13A1

Graphical network of the top 20 diseases related to Angiolipoma:



Diseases related to Angiolipoma

Symptoms & Phenotypes for Angiolipoma

GenomeRNAi Phenotypes related to Angiolipoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.1 CD34 DES F13A1 FH MDM2 VIM

MGI Mouse Phenotypes related to Angiolipoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.56 ACTC1 CD34 DES FH FLCN MDM2
2 homeostasis/metabolism MP:0005376 9.32 ACTC1 CD34 DES F13A1 FH FLCN

Drugs & Therapeutics for Angiolipoma

Drugs for Angiolipoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sirolimus Approved, Investigational Phase 1, Phase 2 53123-88-9 5284616 6436030 46835353
2
Everolimus Approved Phase 1, Phase 2 159351-69-6 6442177 70789204
3
Miconazole Approved, Investigational, Vet_approved Phase 1, Phase 2 22916-47-8 4189
4 Immunologic Factors Phase 1, Phase 2
5 Anti-Infective Agents Phase 1, Phase 2
6 Antibiotics, Antitubercular Phase 1, Phase 2
7 Anti-Bacterial Agents Phase 1, Phase 2
8 Antifungal Agents Phase 1, Phase 2
9 Immunosuppressive Agents Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis Complex and Sporadic Lymphangioleiomyomatosis Completed NCT00792766 Phase 1, Phase 2 everolimus (RAD001)
2 Renal Tumors Classification, Biology, and Banking Study Suspended NCT00898365

Search NIH Clinical Center for Angiolipoma

Cochrane evidence based reviews: angiolipoma

Genetic Tests for Angiolipoma

Anatomical Context for Angiolipoma

MalaCards organs/tissues related to Angiolipoma:

40
Breast, Bone, Skin, Heart, Colon, Kidney, Spinal Cord

Publications for Angiolipoma

Articles related to Angiolipoma:

(show top 50) (show all 463)
# Title Authors PMID Year
1
Clinical and Molecular Investigation of Familial Multiple Lipomatosis: Variants in the HMGA2 Gene. 61
32021365 2020
2
String-like symptomatic angiolipoma of the esophagus. 61
31876060 2019
3
Upper gastrointestinal tract obstruction secondary to transpyloric prolapse of a gastric angiolipoma. 61
30955837 2019
4
Arthroscopic Excision of Angio-Fibro-Lipomatous Hamartoma of the Knee: A Rare Case Report. 61
31673174 2019
5
Exploring a Tumor Spectrum in a Patient with Familial Angiolipomatosis. 61
31497120 2019
6
Microsurgical treatment for spinal epidural angiolipomas. 61
31309454 2019
7
Spinal angiolipoma: Presentation of two cases and review of the literature for the years 2012-2017. 61
31186156 2019
8
Angiolipoma of the Orbit. 61
30908468 2019
9
Giant angiolipoma of the back complicated with ulceration and sepsis: unusual presentation of a rare benign tumour. 61
30602285 2019
10
PET/CT and MR Features of Infiltrating Spinal Angiolipoma. 61
30516665 2019
11
Spinal angiolipomas in pregnancy: Natural history and surgical treatment. 61
30684928 2019
12
Multiple gastric angiolipomas: A case report. 61
30968044 2019
13
Solitary noninfiltrating angiolipoma on the finger, an unusual localization. 61
30865409 2019
14
Spinal angiolipoma. 61
28884558 2019
15
Intratesticular Angiolipoma: A Rare Case of Adipose Tissue Presence in the Testis. 61
31934489 2019
16
A Paratesticular Angiolipoma: A Case Report of a Rare Benign Scrotal Mass and Review of Literature. 61
31321115 2019
17
Spindle cell lipoma: clinicopathologic characterization of 40 cases. 61
31934089 2019
18
Bronchial angiolipoma successfully treated by sleeve resection of the right bronchus intermedius: a case report. 61
30704440 2019
19
Management of Dumbbell and Paraspinal Tumors of the Thoracic Spine Using a Single-stage Posterolateral Approach: Case Series. 61
30406971 2018
20
68Ga-PSMA Uptake in Angiolipoma. 61
30153142 2018
21
Infiltrating angiolipoma of the foot: magnetic resonance imaging features and review of the literature. 61
29322209 2018
22
A Rare Case of Brain Angiolipoma Imitating Arteriovenous Malformation: Differential Diagnosis, Surgical Treatment, and Literature Review. 61
29614355 2018
23
Spinal extradural angiolipoma: a report of two cases and review of literature. 61
30069550 2018
24
Hyperechoic breast images: all that glitters is not gold! 61
29476429 2018
25
Sudden paraplegia due to spontaneous bleeding in a thoracic epidural angiolipoma and literature review. 61
29472020 2018
26
Four cases of spinal epidural angiolipoma. 61
29133105 2018
27
Hemorrhagic Sudden Onset of Spinal Epidural Angiolipoma. 61
30057841 2018
28
Consistent Involvement of Chromosome 13 in Angiolipoma. 61
29275363 2018
29
Spinal angiolipoma mimicking a schwannoma: A case report. 61
29721357 2018
30
Lipomas of cervical area - clinical and pathological considerations. 61
30173259 2018
31
An intraspinal extradural lipoma with spinal epidural lipomatosis: A case report and a review of literature. 61
30488010 2018
32
Epidural angiolipoma: A rare cause of spinal cord compression. 61
29573600 2018
33
Management and Excision of a 15 cm Paratesticular Angiolipoma. 61
28856106 2017
34
Rare cause of colonic intussusception in an adult. 61
28918406 2017
35
Angiolipoma on the Lumbar Spine. 61
29017310 2017
36
Angiolipoma: a rare esophageal submucosal tumor. 61
28237393 2017
37
Adrenal Mass: Unusual Presentation and Outcome. 61
29200669 2017
38
Gastric Angiolipoma: A Rare Entity. 61
28557598 2017
39
Spinal angiolipomas: A puzzling case and review of a rare entity. 61
28694590 2017
40
Frequent low-level mutations of protein kinase D2 in angiolipoma. 61
28139834 2017
41
Epidural spinal angiolipoma: a case series. 61
28320469 2017
42
Percutaneous Endoscopic Removal of a Lumbar Epidural Angiolipoma via Interlaminar Approach: A Technical Report. 61
27890757 2017
43
Cutaneous variant of intravascular large B-cell lymphoma in a Japanese patient: An occult lesion localized in a solitary angiolipoma. 61
27422850 2017
44
Non-Infiltrating Angiolipoma of Floor of Mouth-A Rare Case Report and Literature Review. 61
28384985 2017
45
Imaging review of lipomatous musculoskeletal lesions. 61
28474576 2017
46
Lumbar Spinal Angiolipoma with Expanding Left Neural Foramen Mimicking Lumbar Schwannoma; Case Report and Review of The Literature. 61
29151988 2017
47
Massive noninfiltrating angiolipoma of the buccal mucosa: Report of an extremely rare case. 61
28479700 2017
48
Spinal thoracic extradural angiolipoma manifesting as acute onset of paraparesis: Case report and review of literature. 61
28791193 2017
49
Upper eyelid angiolipoma associated friction in the glide zone. 61
28580224 2017
50
A case report and review of thoracic spinal angiolipoma. 61
28680732 2017

Variations for Angiolipoma

Expression for Angiolipoma

Search GEO for disease gene expression data for Angiolipoma.

Pathways for Angiolipoma

Pathways related to Angiolipoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.66 VIM DES ACTC1

GO Terms for Angiolipoma

Cellular components related to Angiolipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.65 VIM PRKD2 PECAM1 MDM2 FLCN FH
2 cell-cell contact zone GO:0044291 8.62 PECAM1 FLCN

Biological processes related to Angiolipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.56 VIM MDM2 CD34 ACTC1
2 intermediate filament organization GO:0045109 9.16 VIM DES
3 glomerular endothelium development GO:0072011 8.96 PECAM1 CD34
4 muscle filament sliding GO:0030049 8.8 VIM DES ACTC1

Sources for Angiolipoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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