Aliases & Classifications for Angiolipoma

MalaCards integrated aliases for Angiolipoma:

Name: Angiolipoma 12 74 44 15 17 71

Classifications:



External Ids:

Disease Ontology 12 DOID:3616
MeSH 44 D018206
NCIt 50 C3733
SNOMED-CT 67 404057003
UMLS 71 C0206632

Summaries for Angiolipoma

Disease Ontology : 12 A lipoma that is a painful subcutaneous nodule, having all other features of a typical lipoma.

MalaCards based summary : Angiolipoma is related to infiltrating angiolipoma and pleomorphic lipoma. An important gene associated with Angiolipoma is ACTC1 (Actin Alpha Cardiac Muscle 1), and among its related pathways/superpathways are Cytoskeletal Signaling and PI3K / Akt Signaling. The drugs Everolimus and Immunosuppressive Agents have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, colon and tongue, and related phenotypes are cardiovascular system and cellular

Wikipedia : 74 Angiolipoma is a subcutaneous nodule with vascular structure, having all other features of a typical... more...

Related Diseases for Angiolipoma

Diseases related to Angiolipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 304)
# Related Disease Score Top Affiliating Genes
1 infiltrating angiolipoma 31.5 MLANA MDM2 CD34 CALD1
2 pleomorphic lipoma 31.1 MDM2 CD34
3 rare tumor 30.9 DES ACTC1
4 intramuscular hemangioma 30.3 PECAM1 CD34
5 liposarcoma 30.1 VIM MDM2 DES CD34
6 neurilemmoma 29.9 VIM DES CD34 ACTC1
7 intussusception 29.9 PECAM1 CD34
8 hemangioma 29.8 TSC2 PECAM1 CD34 ACTC1
9 spindle cell lipoma 29.7 VIM MDM2 DES CD34 ACTC1
10 gastrointestinal stromal tumor 29.7 VIM DES CD34 ACTC1
11 kidney angiomyolipoma 29.6 TSC2 MLANA FLCN
12 lipomatosis, multiple 29.6 PECAM1 MLANA MDM2 DES CD34 CALD1
13 angiomyolipoma 29.6 VIM TSC2 MLANA DES ACTC1
14 tuberous sclerosis 29.6 VIM TSC2 MLANA FLCN
15 mesenchymal cell neoplasm 29.5 PECAM1 MLANA CD34 CALD1
16 congenital heart defects, hamartomas of tongue, and polysyndactyly 29.5 TSC2 FLCN
17 angiosarcoma 29.5 VIM PECAM1 MLANA CD34
18 capillary hemangioma 29.5 PECAM1 CD34
19 hepatic angiomyolipoma 29.4 TSC2 MLANA CD34
20 spindle cell sarcoma 29.1 VIM MDM2 DES CD34 CALD1 ACTC1
21 leiomyoma 29.0 VIM TSC2 DES CD34 ACTC1
22 fibroma 28.9 VIM PECAM1 F13A1 DES CD34 ACTC1
23 dedifferentiated liposarcoma 28.8 MDM2 F13A1 DES CD34 CALD1 ACTC1
24 connective tissue benign neoplasm 28.2 TSC2 PECAM1 MLANA MDM2 CD34 CALD1
25 epidural spinal canal angiolipoma 11.2
26 angiolipomatosis, familial 11.0
27 lymphangiectasis 10.4 VIM ACTC1
28 intravascular papillary endothelial hyperplasia 10.4 VIM ACTC1
29 ovarian fibrothecoma 10.4 DES ACTC1
30 infantile digital fibromatosis 10.3 VIM DES
31 progressive nodular histiocytosis 10.3 F13A1 ACTC1
32 primitive neuroectodermal tumor of the cervix uteri 10.3 VIM DES
33 scleromyxedema 10.3 F13A1 ACTC1
34 tumor of meninges 10.3 VIM F13A1
35 angiocentric glioma 10.3 VIM ACTC1
36 adult cystic nephroma 10.3 DES ACTC1
37 congenital epulis 10.3 VIM DES
38 epulis 10.3 VIM DES
39 botryoid rhabdomyosarcoma 10.3 DES ACTC1
40 syringocystadenoma papilliferum 10.3 DES ACTC1
41 multicentric reticulohistiocytosis 10.3 VIM F13A1
42 liver fibroma 10.3 VIM CD34
43 paraplegia 10.3
44 polymorphous low-grade adenocarcinoma 10.3 VIM ACTC1
45 granuloma annulare 10.3 VIM F13A1
46 granulosa cell tumor of the ovary 10.3 VIM ACTC1
47 dendritic cell tumor 10.3 VIM ACTC1
48 spiradenoma 10.3 VIM ACTC1
49 biphasic synovial sarcoma 10.3 VIM DES
50 benign breast phyllodes tumor 10.3 VIM CD34

Graphical network of the top 20 diseases related to Angiolipoma:



Diseases related to Angiolipoma

Symptoms & Phenotypes for Angiolipoma

MGI Mouse Phenotypes related to Angiolipoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.86 ACTC1 DES F13A1 FLCN MDM2 PECAM1
2 cellular MP:0005384 9.76 ACTC1 CD34 DES FLCN MDM2 PECAM1
3 hematopoietic system MP:0005397 9.61 ACTC1 CD34 F13A1 FLCN MDM2 PECAM1
4 homeostasis/metabolism MP:0005376 9.32 ACTC1 CD34 DES F13A1 FLCN MDM2

Drugs & Therapeutics for Angiolipoma

Drugs for Angiolipoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Everolimus Approved Phase 1, Phase 2 159351-69-6 6442177 70789204
2 Immunosuppressive Agents Phase 1, Phase 2
3 Immunologic Factors Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis Complex and Sporadic Lymphangioleiomyomatosis Completed NCT00792766 Phase 1, Phase 2 everolimus (RAD001)
2 Renal Tumors Classification, Biology, and Banking Study Recruiting NCT00898365

Search NIH Clinical Center for Angiolipoma

Cochrane evidence based reviews: angiolipoma

Genetic Tests for Angiolipoma

Anatomical Context for Angiolipoma

MalaCards organs/tissues related to Angiolipoma:

40
Spinal Cord, Colon, Tongue, Skeletal Muscle, Kidney, Salivary Gland, Skin

Publications for Angiolipoma

Articles related to Angiolipoma:

(show top 50) (show all 482)
# Title Authors PMID Year
1
Frequent activating PIK3CA mutations in sporadic angiolipoma. 61
32662895 2021
2
Esophageal Lipoma and Liposarcoma: A Systematic Review. 61
33026474 2021
3
Telocytes/CD34+ Stromal Cells in Pathologically Affected White Adipose Tissue. 61
33353193 2020
4
Lumbar Extradural Angiolipoma: Clinical Presentation and Management. 61
33527059 2020
5
Recurrent Intramuscular Hemangioma (Infiltrating Angiolipoma) of the Lower Lip: A Case Report and Review of the Literature. 61
32921186 2020
6
Rare localization of angiolipoma in the gastrointestinal tract: a case series. 61
32972286 2020
7
Prostate-specific membrane antigen expressing angiolipoma. 61
32956558 2020
8
A rare case of scrotal angiolipoma and the literature review. 61
32382509 2020
9
Spinal angiolipoma: a report of two cases and review of the literature. 61
32972280 2020
10
Intraosseous angiolipoma of the mandible: An unexpected diagnosis. 61
32205303 2020
11
Cranial intraosseous angiolipoma: case report and literature review. 61
32844077 2020
12
Sacral Extradural Angiolipoma Associated with Tight Filum Terminale and Spina Bifida Coexisting with Spinal Arteriovenous Fistula. 61
32407913 2020
13
Epidural angiolipoma with concomitant intradural extramedullary capillary hemangioma at the same spinal level: A case report. 61
32565948 2020
14
Spinal angiolipoma-a rare but reversible cause of paraplegia in a child. 61
32052158 2020
15
Angiolipoma in the Head and Neck: Imaging, Diagnosis and Management. 61
32532063 2020
16
A scoring system based on clinical features for the prediction of sporadic renal angiomyolipoma rupture and hemorrhage. 61
32443333 2020
17
Esophageal Angiolipoma: A Tongue-Like Mucosal Mass. 61
32200089 2020
18
Spinal angiolipoma: Presentation of two cases and review of the literature for the years 2012-2017. 61
31186156 2020
19
String-like symptomatic angiolipoma of the esophagus. 61
31876060 2020
20
Foreign Body (Solder) and Reaction to the Foreign Body Presenting As a Cutaneous Tender Tumor: Case Report and a New Acronym to Aid in Recalling the Differential Diagnosis of Painful Skin Lesions. 61
32190505 2020
21
Clinical and Molecular Investigation of Familial Multiple Lipomatosis: Variants in the HMGA2 Gene. 61
32021365 2020
22
Endoscopic Submucosal Dissection of the Angiolipoma at Hypopharynx-Esophageal Introitus. 61
32148476 2020
23
Medical and Legal Implications of MRI Scout Imaging in a Surgical Patient with Case Presentation. 61
32181076 2020
24
Upper gastrointestinal tract obstruction secondary to transpyloric prolapse of a gastric angiolipoma. 61
30955837 2019
25
Arthroscopic Excision of Angio-Fibro-Lipomatous Hamartoma of the Knee: A Rare Case Report. 61
31673174 2019
26
Exploring a Tumor Spectrum in a Patient with Familial Angiolipomatosis. 61
31497120 2019
27
Microsurgical treatment for spinal epidural angiolipomas. 61
31309454 2019
28
Angiolipoma of the Orbit. 61
30908468 2019
29
Spinal angiolipomas in pregnancy: Natural history and surgical treatment. 61
30684928 2019
30
Multiple gastric angiolipomas: A case report. 61
30968044 2019
31
PET/CT and MR Features of Infiltrating Spinal Angiolipoma. 61
30516665 2019
32
Giant angiolipoma of the back complicated with ulceration and sepsis: unusual presentation of a rare benign tumour. 61
30602285 2019
33
Solitary noninfiltrating angiolipoma on the finger, an unusual localization. 61
30865409 2019
34
Spinal angiolipoma. 61
28884558 2019
35
A Paratesticular Angiolipoma: A Case Report of a Rare Benign Scrotal Mass and Review of Literature. 61
31321115 2019
36
Intratesticular Angiolipoma: A Rare Case of Adipose Tissue Presence in the Testis. 61
31934489 2019
37
Bronchial angiolipoma successfully treated by sleeve resection of the right bronchus intermedius: a case report. 61
30704440 2019
38
Spindle cell lipoma: clinicopathologic characterization of 40 cases. 61
31934089 2019
39
Management of Dumbbell and Paraspinal Tumors of the Thoracic Spine Using a Single-stage Posterolateral Approach: Case Series. 61
30406971 2018
40
68Ga-PSMA Uptake in Angiolipoma. 61
30153142 2018
41
Spinal extradural angiolipoma: a report of two cases and review of literature. 61
30069550 2018
42
A Rare Case of Brain Angiolipoma Imitating Arteriovenous Malformation: Differential Diagnosis, Surgical Treatment, and Literature Review. 61
29614355 2018
43
Infiltrating angiolipoma of the foot: magnetic resonance imaging features and review of the literature. 61
29322209 2018
44
Hyperechoic breast images: all that glitters is not gold! 61
29476429 2018
45
Sudden paraplegia due to spontaneous bleeding in a thoracic epidural angiolipoma and literature review. 61
29472020 2018
46
Four cases of spinal epidural angiolipoma. 61
29133105 2018
47
Spinal angiolipoma mimicking a schwannoma: A case report. 61
29721357 2018
48
Hemorrhagic Sudden Onset of Spinal Epidural Angiolipoma. 61
30057841 2018
49
Epidural angiolipoma: A rare cause of spinal cord compression. 61
29573600 2018
50
Consistent Involvement of Chromosome 13 in Angiolipoma. 61
29275363 2018

Variations for Angiolipoma

Expression for Angiolipoma

Search GEO for disease gene expression data for Angiolipoma.

Pathways for Angiolipoma

Pathways related to Angiolipoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.75 VIM DES CALD1 ACTC1
2 11.3 TSC2 PRKD2 MDM2
3 10.66 VIM DES ACTC1

GO Terms for Angiolipoma

Cellular components related to Angiolipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.32 VIM TSC2 PRKD2 MDM2 FLCN F13A1

Biological processes related to Angiolipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.56 VIM MDM2 CD34 ACTC1
2 negative regulation of TOR signaling GO:0032007 9.32 TSC2 FLCN
3 intermediate filament organization GO:0045109 9.16 VIM DES
4 glomerular endothelium development GO:0072011 8.96 PECAM1 CD34
5 muscle filament sliding GO:0030049 8.8 VIM DES ACTC1

Molecular functions related to Angiolipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 myosin binding GO:0017022 8.62 CALD1 ACTC1

Sources for Angiolipoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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