MCID: ANG009
MIFTS: 34

Angiomatous Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Angiomatous Meningioma

MalaCards integrated aliases for Angiomatous Meningioma:

Name: Angiomatous Meningioma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:6548
MeSH 44 D008579
NCIt 50 C4332
SNOMED-CT 68 73918009
UMLS 73 C0334608

Summaries for Angiomatous Meningioma

MalaCards based summary : Angiomatous Meningioma is related to meningioma, familial and pancreatic serous cystadenoma. An important gene associated with Angiomatous Meningioma is SEMA3A (Semaphorin 3A), and among its related pathways/superpathways are Development VEGF signaling via VEGFR2 - generic cascades and Immune response IFN alpha/beta signaling pathway. Affiliated tissues include skin, brain and breast, and related phenotypes are cardiovascular system and cellular

Related Diseases for Angiomatous Meningioma

Diseases related to Angiomatous Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 meningioma, familial 30.1 GFAP PGR VEGFA
2 pancreatic serous cystadenoma 10.2 PGR VEGFA
3 preretinal fibrosis 10.2 GFAP VEGFA
4 pediatric angiosarcoma 10.2 HBA1 VEGFA
5 hypoglycemic coma 10.2 HBA1 VEGFA
6 glomeruloid hemangioma 10.2 HBA1 VEGFA
7 angiokeratoma circumscriptum 10.1 KDR VEGFA
8 clear cell meningioma 10.1 GFAP PGR
9 suprasellar meningioma 10.1 GFAP PGR
10 microcystic meningioma 10.1 GFAP VEGFA
11 folic acid deficiency anemia 10.1 TF TFRC
12 brachial plexus lesion 10.1 NRP1 SEMA3A WDFY2
13 exudative vitreoretinopathy 1 10.1 KDR NRP1 VEGFA
14 breast carcinoma in situ 10.1 KDR PGR VEGFA
15 lipodermatosclerosis 10.0 PLAUR VEGFA
16 skin hemangioma 10.0 HBA1 KDR VEGFA
17 capillary hemangioma 10.0 HBA1 KDR VEGFA
18 supratentorial cancer 10.0 GFAP KDR VEGFA
19 cerebrum cancer 10.0 GFAP KDR VEGFA
20 drug-induced lupus erythematosus 10.0 HBA1 KDR VEGFA
21 cornea cancer 10.0 FGF2 GFAP
22 lymphangioma 10.0 HBA1 KDR VEGFA
23 chronic myocardial ischemia 10.0 FGF2 VEGFA
24 epithelioid hemangioendothelioma 10.0 KDR VEGFA
25 papillary hidradenoma 10.0 GAPDH PGR WDFY2
26 retinal vascular disease 10.0 HBA1 KDR VEGFA
27 juvenile nasopharyngeal angiofibroma 10.0 FGF2 PGR VEGFA
28 sturge-weber syndrome 10.0
29 hemangiopericytoma, malignant 10.0
30 spinal meningioma 10.0
31 secretory meningioma 10.0
32 hemangioblastoma 10.0
33 weber syndrome 10.0
34 angiodysplasia 10.0 FGF2 VEGFA
35 endometrial adenocarcinoma 10.0 FGF2 PGR VEGFA
36 vitreous disease 10.0 FGF2 GFAP VEGFA
37 hemoglobin h disease 10.0 HBA1 TF TFRC
38 gastric signet ring cell adenocarcinoma 10.0 FGF2 PGR
39 microcytic anemia 10.0 HBA1 TF TFRC
40 deep angioma 10.0 MEG8 PGR
41 connective tissue cancer 10.0 FGF2 HBA1 VEGFA
42 thalassemia 10.0 HBA1 TF TFRC
43 hemangioma 10.0 FGF2 KDR VEGFA
44 microvascular complications of diabetes 1 10.0 FGF2 GFAP VEGFA
45 beta-thalassemia 9.9 HBA1 TF TFRC
46 corneal neovascularization 9.9 FGF2 KDR VEGFA
47 senile angioma 9.9 HBA1 KDR TF
48 limb ischemia 9.9 FGF2 KDR VEGFA
49 microvascular complications of diabetes 5 9.9 FGF2 KDR VEGFA
50 intramuscular hemangioma 9.9 MEG8 PGR

Graphical network of the top 20 diseases related to Angiomatous Meningioma:



Diseases related to Angiomatous Meningioma

Symptoms & Phenotypes for Angiomatous Meningioma

MGI Mouse Phenotypes related to Angiomatous Meningioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.96 FGF2 GFAP KDR MMP11 NRP1 PGR
2 cellular MP:0005384 9.81 FGF2 GFAP KDR NRP1 PGR PLAUR
3 hematopoietic system MP:0005397 9.61 FGF2 KDR NRP1 PGR PLAUR SEMA3A
4 muscle MP:0005369 9.17 FGF2 GFAP KDR NRP1 PGR PLAUR

Drugs & Therapeutics for Angiomatous Meningioma

Search Clinical Trials , NIH Clinical Center for Angiomatous Meningioma

Genetic Tests for Angiomatous Meningioma

Anatomical Context for Angiomatous Meningioma

MalaCards organs/tissues related to Angiomatous Meningioma:

41
Skin, Brain, Breast, Ovary

Publications for Angiomatous Meningioma

Articles related to Angiomatous Meningioma:

(show all 16)
# Title Authors Year
1
Preoperative Prediction of Solitary Fibrous Tumor/Hemangiopericytoma and Angiomatous Meningioma Using Magnetic Resonance Imaging Texture Analysis. ( 30240864 )
2018
2
Intradural angiomatous meningioma arising from a thoracic nerve root. ( 28868199 )
2017
3
Angiomatous meningioma have a very benign outcome despite frequent peritumoral edema at onset. ( 28844928 )
2017
4
Epidural angiomatous meningioma of the thoracic spine: A case report. ( 26870233 )
2016
5
Intraparenchymal Angiomatous Meningioma: A Diagnostic Dilemma. ( 26557529 )
2015
6
Preoperative radiologic characters to predict hemangiopericytoma from angiomatous meningioma. ( 26298537 )
2015
7
Angiomatous meningioma in Sturge-Weber syndrome. ( 25766367 )
2015
8
Elevated numbers of mast cells in angiomatous meningioma. ( 25207622 )
2014
9
Angiomatous meningioma of orbit mimicking as malignant neoplasm: a case report and literature review. ( 21780930 )
2011
10
Cystic angiomatous meningioma in the cerebellopontine angle mimicking hemangioblastoma. ( 21358102 )
2010
11
Angiomatous meningioma: a diagnostic dilemma. ( 18417856 )
2008
12
Angiomatous meningioma: a clinicopathologic study of 38 cases. ( 15104303 )
2004
13
Primary orbital angiomatous meningioma. ( 12523900 )
2003
14
A case of cystic form of angiomatous meningioma with prominent microvascular pattern mimicking haemangioblastoma. ( 11680633 )
2001
15
Fine structure of intracranial hemangiopericytoma and angiomatous meningioma. ( 4417339 )
1974
16
Suprasellar angiomatous meningioma simulating a large carotid aneurysm; report of case. ( 13413420 )
1957

Variations for Angiomatous Meningioma

Expression for Angiomatous Meningioma

Search GEO for disease gene expression data for Angiomatous Meningioma.

Pathways for Angiomatous Meningioma

Pathways related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

(show all 19)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.17 KDR NRP1 PLAUR VEGFA
2
Show member pathways
12.05 FGF2 KDR NRP1 SEMA3A
3 12.04 FGF2 KDR PLAUR VEGFA
4 11.97 GAPDH TF VEGFA
5 11.86 FGF2 KDR VEGFA
6
Show member pathways
11.81 FGF2 KDR NRP1 VEGFA
7
Show member pathways
11.65 KDR NRP1 VEGFA
8 11.57 FGF2 GFAP VEGFA
9 11.45 TF TFRC VEGFA
10 11.27 FGF2 KDR VEGFA
11 11.23 FGF2 TF VEGFA
12 11.16 FGF2 KDR VEGFA
13 10.99 FGF2 VEGFA
14 10.96 FGF2 KDR VEGFA
15 10.92 GAPDH TF TFRC VEGFA
16 10.89 FGF2 KDR VEGFA
17
Show member pathways
10.75 KDR VEGFA
18 10.6 TF TFRC
19 10.51 FGF2 KDR VEGFA

GO Terms for Angiomatous Meningioma

Cellular components related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.95 FGF2 HBA1 NRP1 SEMA3A TF TFRC
2 cell surface GO:0009986 9.77 NRP1 PLAUR TF TFRC VEGFA
3 vesicle GO:0031982 9.63 GAPDH TF WDFY2
4 blood microparticle GO:0072562 9.61 HBA1 TF TFRC
5 early endosome GO:0005769 9.35 KDR NRP1 TF TFRC WDFY2
6 neurofilament GO:0005883 9.32 GFAP NRP1
7 extracellular region GO:0005576 9.32 FGF2 HBA1 KDR MMP11 NRP1 PLAUR
8 HFE-transferrin receptor complex GO:1990712 9.26 TF TFRC
9 sorting endosome GO:0097443 9.16 KDR NRP1

Biological processes related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

(show top 50) (show all 51)
# Name GO ID Score Top Affiliating Genes
1 angiogenesis GO:0001525 9.97 FGF2 KDR NRP1 VEGFA
2 extracellular matrix organization GO:0030198 9.94 FGF2 GFAP KDR MMP11
3 positive regulation of protein phosphorylation GO:0001934 9.91 KDR PLAUR VEGFA WDFY2
4 positive regulation of angiogenesis GO:0045766 9.85 FGF2 KDR NRP1 VEGFA
5 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.83 KDR NRP1 VEGFA
6 positive regulation of endothelial cell migration GO:0010595 9.79 KDR NRP1 VEGFA
7 positive regulation of blood vessel endothelial cell migration GO:0043536 9.77 FGF2 KDR VEGFA
8 positive chemotaxis GO:0050918 9.77 FGF2 NRP1 VEGFA
9 negative regulation of axon extension involved in axon guidance GO:0048843 9.71 NRP1 SEMA3A
10 artery morphogenesis GO:0048844 9.71 NRP1 VEGFA
11 motor neuron axon guidance GO:0008045 9.71 NRP1 SEMA3A
12 axonal fasciculation GO:0007413 9.7 NRP1 SEMA3A
13 negative regulation of axon extension GO:0030517 9.7 NRP1 SEMA3A
14 sympathetic nervous system development GO:0048485 9.7 NRP1 SEMA3A
15 nerve development GO:0021675 9.7 NRP1 SEMA3A
16 commissural neuron axon guidance GO:0071679 9.69 NRP1 VEGFA
17 positive regulation of positive chemotaxis GO:0050927 9.69 KDR VEGFA
18 semaphorin-plexin signaling pathway involved in axon guidance GO:1902287 9.68 NRP1 SEMA3A
19 coronary artery morphogenesis GO:0060982 9.68 NRP1 VEGFA
20 endothelial cell chemotaxis GO:0035767 9.68 NRP1 VEGFA
21 facial nerve structural organization GO:0021612 9.68 NRP1 SEMA3A
22 sympathetic ganglion development GO:0061549 9.67 NRP1 SEMA3A
23 axon extension involved in axon guidance GO:0048846 9.67 NRP1 SEMA3A
24 paracrine signaling GO:0038001 9.66 FGF2 PGR
25 positive regulation of axon extension involved in axon guidance GO:0048842 9.66 NRP1 VEGFA
26 axonogenesis involved in innervation GO:0060385 9.65 NRP1 SEMA3A
27 branchiomotor neuron axon guidance GO:0021785 9.65 NRP1 SEMA3A
28 neural crest cell migration involved in autonomic nervous system development GO:1901166 9.64 NRP1 SEMA3A
29 dichotomous subdivision of terminal units involved in salivary gland branching GO:0060666 9.63 NRP1 SEMA3A
30 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway GO:0038033 9.63 KDR VEGFA
31 cellular response to vascular endothelial growth factor stimulus GO:0035924 9.63 KDR NRP1 VEGFA
32 trigeminal ganglion development GO:0061551 9.62 NRP1 SEMA3A
33 trigeminal nerve structural organization GO:0021637 9.62 NRP1 SEMA3A
34 semaphorin-plexin signaling pathway involved in neuron projection guidance GO:1902285 9.58 NRP1 SEMA3A
35 sympathetic neuron projection extension GO:0097490 9.58 NRP1 SEMA3A
36 sympathetic neuron projection guidance GO:0097491 9.57 NRP1 SEMA3A
37 ventral trunk neural crest cell migration GO:0036486 9.56 NRP1 SEMA3A
38 basal dendrite arborization GO:0150020 9.54 NRP1 SEMA3A
39 facioacoustic ganglion development GO:1903375 9.52 NRP1 SEMA3A
40 gonadotrophin-releasing hormone neuronal migration to the hypothalamus GO:0021828 9.51 NRP1 SEMA3A
41 positive regulation of focal adhesion assembly GO:0051894 9.5 KDR NRP1 VEGFA
42 regulation of axon extension involved in axon guidance GO:0048841 9.49 NRP1 SEMA3A
43 regulation of retinal ganglion cell axon guidance GO:0090259 9.48 NRP1 VEGFA
44 positive regulation of endothelial cell proliferation GO:0001938 9.46 FGF2 KDR NRP1 VEGFA
45 motor neuron migration GO:0097475 9.43 NRP1 VEGFA
46 vascular endothelial growth factor signaling pathway GO:0038084 9.43 KDR NRP1 VEGFA
47 positive regulation of retinal ganglion cell axon guidance GO:1902336 9.4 NRP1 VEGFA
48 VEGF-activated neuropilin signaling pathway GO:0038190 9.37 NRP1 VEGFA
49 positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 9.26 FGF2 KDR NRP1 VEGFA
50 cell migration involved in sprouting angiogenesis GO:0002042 8.92 FGF2 KDR NRP1 VEGFA

Molecular functions related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.63 GAPDH GFAP KDR PGR TFRC VEGFA
2 heparin binding GO:0008201 9.5 FGF2 NRP1 VEGFA
3 integrin binding GO:0005178 9.43 FGF2 GFAP KDR
4 vascular endothelial growth factor-activated receptor activity GO:0005021 8.96 KDR NRP1
5 vascular endothelial growth factor binding GO:0038085 8.62 KDR NRP1

Sources for Angiomatous Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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