MCID: ANG009
MIFTS: 34

Angiomatous Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Angiomatous Meningioma

MalaCards integrated aliases for Angiomatous Meningioma:

Name: Angiomatous Meningioma 12 15 17 74

Classifications:



External Ids:

Disease Ontology 12 DOID:6548
MeSH 45 D008579
NCIt 51 C4332
SNOMED-CT 69 73918009
UMLS 74 C0334608

Summaries for Angiomatous Meningioma

MalaCards based summary : Angiomatous Meningioma is related to meningioma, familial and spinal meningioma. An important gene associated with Angiomatous Meningioma is MMP11 (Matrix Metallopeptidase 11), and among its related pathways/superpathways are Degradation of the extracellular matrix and Development VEGF signaling via VEGFR2 - generic cascades. Affiliated tissues include skin, brain and breast, and related phenotypes are cardiovascular system and cellular

Related Diseases for Angiomatous Meningioma

Diseases related to Angiomatous Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
# Related Disease Score Top Affiliating Genes
1 meningioma, familial 30.5 GFAP PGR UBE2D1 VEGFA
2 spinal meningioma 10.5
3 secretory meningioma 10.5
4 hemangiopericytoma, malignant 10.3
5 pancreatic serous cystadenoma 10.3 PGR VEGFA
6 preretinal fibrosis 10.3 GFAP VEGFA
7 clear cell meningioma 10.2 GFAP PGR
8 microcystic meningioma 10.2 GFAP VEGFA
9 angiokeratoma circumscriptum 10.2 KDR VEGFA
10 suprasellar meningioma 10.2 GFAP PGR
11 hemangioendothelioma 10.1 KDR PECAM1
12 kaposiform hemangioendothelioma 10.1 KDR PECAM1
13 skin hemangioma 10.1 KDR VEGFA
14 chronic myocardial ischemia 10.1 FGF2 VEGFA
15 lipodermatosclerosis 10.1 PLAUR VEGFA
16 cornea cancer 10.1 FGF2 GFAP
17 angiodysplasia 10.1 FGF2 VEGFA
18 exudative vitreoretinopathy 1 10.1 KDR NRP1 VEGFA
19 brachial plexus lesion 10.1 NRP1 SEMA3A WDFY2
20 pulmonary vein stenosis 10.1 KDR PECAM1
21 epithelioid hemangioendothelioma 10.1 KDR VEGFA
22 gastric signet ring cell adenocarcinoma 10.1 FGF2 PGR
23 breast carcinoma in situ 10.1 FGF2 PGR VEGFA
24 supratentorial cancer 10.0 GFAP KDR VEGFA
25 cerebrum cancer 10.0 GFAP KDR VEGFA
26 capillary hemangioma 10.0 KDR PECAM1 VEGFA
27 endometrial adenocarcinoma 10.0 FGF2 PGR VEGFA
28 poems syndrome 10.0 FGF2 VEGFA
29 vitreous disease 10.0 FGF2 GFAP VEGFA
30 papillary hidradenoma 10.0 GAPDH PGR WDFY2
31 angiosarcoma 10.0 KDR PECAM1 VEGFA
32 sturge-weber syndrome 10.0
33 hemangioblastoma 10.0
34 weber syndrome 10.0
35 hydrocele 10.0 PECAM1 VEGFA
36 microvascular complications of diabetes 1 10.0 FGF2 GFAP VEGFA
37 deep angioma 10.0 MEG8 PGR
38 vascular cancer 10.0 FGF2 KDR VEGFA
39 corneal neovascularization 10.0 FGF2 KDR VEGFA
40 limb ischemia 10.0 FGF2 KDR VEGFA
41 microvascular complications of diabetes 5 9.9 FGF2 KDR VEGFA
42 intramuscular hemangioma 9.9 MEG8 PGR
43 kaposi sarcoma 9.9 FGF2 KDR VEGFA
44 cavernous hemangioma 9.9 FGF2 KDR PECAM1
45 drug-induced lupus erythematosus 9.9 KDR VEGFA
46 juvenile nasopharyngeal angiofibroma 9.8 FGF2 PECAM1 PGR VEGFA
47 radiation proctitis 9.7 FGF2 KDR PECAM1 VEGFA
48 hemangioma 9.7 FGF2 KDR PECAM1 VEGFA
49 malaria 9.7 GAPDH PECAM1 PLAUR TFRC VEGFA
50 brain cancer 9.4 FGF2 GFAP KDR PLAUR TFRC VEGFA

Graphical network of the top 20 diseases related to Angiomatous Meningioma:



Diseases related to Angiomatous Meningioma

Symptoms & Phenotypes for Angiomatous Meningioma

MGI Mouse Phenotypes related to Angiomatous Meningioma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.06 FGF2 GFAP KDR MMP11 NRP1 PECAM1
2 cellular MP:0005384 9.96 FGF2 GFAP KDR NRP1 PECAM1 PGR
3 hematopoietic system MP:0005397 9.81 FGF2 KDR NRP1 PECAM1 PGR PLAUR
4 immune system MP:0005387 9.61 GFAP KDR NRP1 PECAM1 PGR PLAUR
5 muscle MP:0005369 9.23 FGF2 GFAP KDR NRP1 PECAM1 PGR

Drugs & Therapeutics for Angiomatous Meningioma

Search Clinical Trials , NIH Clinical Center for Angiomatous Meningioma

Genetic Tests for Angiomatous Meningioma

Anatomical Context for Angiomatous Meningioma

MalaCards organs/tissues related to Angiomatous Meningioma:

42
Skin, Brain, Breast

Publications for Angiomatous Meningioma

Articles related to Angiomatous Meningioma:

(show all 17)
# Title Authors Year
1
Whole-tumor histogram analysis of apparent diffusion coefficient in differentiating intracranial solitary fibrous tumor/hemangiopericytoma from angiomatous meningioma. ( 30777209 )
2019
2
Application of Dextroscope in a Rare Type of Angiomatous Meningioma Characterized With Coral-Like Vessels. ( 30946223 )
2019
3
Preoperative Prediction of Solitary Fibrous Tumor/Hemangiopericytoma and Angiomatous Meningioma Using Magnetic Resonance Imaging Texture Analysis. ( 30240864 )
2018
4
Intradural angiomatous meningioma arising from a thoracic nerve root. ( 28868199 )
2017
5
Epidural angiomatous meningioma of the thoracic spine: A case report. ( 26870233 )
2016
6
Angiomatous meningioma in Sturge-Weber syndrome. ( 25766367 )
2015
7
Preoperative radiologic characters to predict hemangiopericytoma from angiomatous meningioma. ( 26298537 )
2015
8
Intraparenchymal Angiomatous Meningioma: A Diagnostic Dilemma. ( 26557529 )
2015
9
Elevated numbers of mast cells in angiomatous meningioma. ( 25207622 )
2015
10
Angiomatous meningioma of orbit mimicking as malignant neoplasm: a case report and literature review. ( 21780930 )
2011
11
Cystic angiomatous meningioma in the cerebellopontine angle mimicking hemangioblastoma. ( 21358102 )
2010
12
Angiomatous meningioma: a diagnostic dilemma. ( 18417856 )
2008
13
Angiomatous meningioma: a clinicopathologic study of 38 cases. ( 15104303 )
2004
14
Primary orbital angiomatous meningioma. ( 12523900 )
2003
15
A case of cystic form of angiomatous meningioma with prominent microvascular pattern mimicking haemangioblastoma. ( 11680633 )
2001
16
Fine structure of intracranial hemangiopericytoma and angiomatous meningioma. ( 4417339 )
1974
17
Suprasellar angiomatous meningioma simulating a large carotid aneurysm; report of case. ( 13413420 )
1957

Variations for Angiomatous Meningioma

Expression for Angiomatous Meningioma

Search GEO for disease gene expression data for Angiomatous Meningioma.

Pathways for Angiomatous Meningioma

Pathways related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

(show all 17)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.52 FGF2 KDR MMP11 PECAM1
2
Show member pathways
12.09 KDR NRP1 PLAUR VEGFA
3
Show member pathways
12.02 FGF2 KDR NRP1 SEMA3A
4 11.97 FGF2 KDR PLAUR VEGFA
5 11.86 KDR PECAM1 VEGFA
6 11.82 FGF2 KDR VEGFA
7
Show member pathways
11.81 FGF2 KDR NRP1 VEGFA
8 11.67 GAPDH TFRC VEGFA
9
Show member pathways
11.62 KDR NRP1 VEGFA
10 11.58 FGF2 KDR PECAM1
11 11.51 FGF2 GFAP VEGFA
12 11.19 FGF2 KDR VEGFA
13 10.99 FGF2 KDR VEGFA
14 10.97 FGF2 VEGFA
15 10.87 FGF2 KDR VEGFA
16 10.77 FGF2 KDR VEGFA
17 10.18 FGF2 KDR VEGFA

GO Terms for Angiomatous Meningioma

Cellular components related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.86 FGF2 KDR MMP11 NRP1 PLAUR SEMA3A
2 early endosome GO:0005769 9.26 KDR NRP1 TFRC WDFY2
3 neurofilament GO:0005883 9.16 GFAP NRP1
4 sorting endosome GO:0097443 8.62 KDR NRP1

Biological processes related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

(show top 50) (show all 53)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of protein phosphorylation GO:0001934 9.92 KDR PLAUR VEGFA WDFY2
2 positive regulation of angiogenesis GO:0045766 9.87 FGF2 KDR NRP1 VEGFA
3 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.83 KDR NRP1 VEGFA
4 positive regulation of endothelial cell migration GO:0010595 9.8 KDR NRP1 VEGFA
5 positive regulation of blood vessel endothelial cell migration GO:0043536 9.79 FGF2 KDR VEGFA
6 positive chemotaxis GO:0050918 9.78 FGF2 NRP1 VEGFA
7 angiogenesis GO:0001525 9.77 FGF2 KDR NRP1 PECAM1 VEGFA
8 branching involved in blood vessel morphogenesis GO:0001569 9.71 NRP1 VEGFA
9 positive regulation of sprouting angiogenesis GO:1903672 9.71 FGF2 VEGFA
10 negative regulation of axon extension involved in axon guidance GO:0048843 9.71 NRP1 SEMA3A
11 artery morphogenesis GO:0048844 9.71 NRP1 VEGFA
12 motor neuron axon guidance GO:0008045 9.71 NRP1 SEMA3A
13 axonal fasciculation GO:0007413 9.7 NRP1 SEMA3A
14 negative regulation of axon extension GO:0030517 9.7 NRP1 SEMA3A
15 sympathetic nervous system development GO:0048485 9.7 NRP1 SEMA3A
16 nerve development GO:0021675 9.7 NRP1 SEMA3A
17 commissural neuron axon guidance GO:0071679 9.69 NRP1 VEGFA
18 positive regulation of positive chemotaxis GO:0050927 9.69 KDR VEGFA
19 semaphorin-plexin signaling pathway involved in axon guidance GO:1902287 9.68 NRP1 SEMA3A
20 coronary artery morphogenesis GO:0060982 9.68 NRP1 VEGFA
21 endothelial cell chemotaxis GO:0035767 9.68 NRP1 VEGFA
22 facial nerve structural organization GO:0021612 9.68 NRP1 SEMA3A
23 sympathetic ganglion development GO:0061549 9.67 NRP1 SEMA3A
24 axon extension involved in axon guidance GO:0048846 9.67 NRP1 SEMA3A
25 paracrine signaling GO:0038001 9.67 FGF2 PGR
26 cellular response to vascular endothelial growth factor stimulus GO:0035924 9.67 KDR NRP1 VEGFA
27 positive regulation of axon extension involved in axon guidance GO:0048842 9.66 NRP1 VEGFA
28 axonogenesis involved in innervation GO:0060385 9.65 NRP1 SEMA3A
29 branchiomotor neuron axon guidance GO:0021785 9.65 NRP1 SEMA3A
30 neural crest cell migration involved in autonomic nervous system development GO:1901166 9.65 NRP1 SEMA3A
31 extracellular matrix organization GO:0030198 9.65 FGF2 GFAP KDR MMP11 PECAM1
32 dichotomous subdivision of terminal units involved in salivary gland branching GO:0060666 9.64 NRP1 SEMA3A
33 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway GO:0038033 9.64 KDR VEGFA
34 trigeminal ganglion development GO:0061551 9.63 NRP1 SEMA3A
35 trigeminal nerve structural organization GO:0021637 9.63 NRP1 SEMA3A
36 semaphorin-plexin signaling pathway involved in neuron projection guidance GO:1902285 9.6 NRP1 SEMA3A
37 sympathetic neuron projection extension GO:0097490 9.59 NRP1 SEMA3A
38 sympathetic neuron projection guidance GO:0097491 9.58 NRP1 SEMA3A
39 ventral trunk neural crest cell migration GO:0036486 9.58 NRP1 SEMA3A
40 positive regulation of focal adhesion assembly GO:0051894 9.58 KDR NRP1 VEGFA
41 basal dendrite arborization GO:0150020 9.56 NRP1 SEMA3A
42 facioacoustic ganglion development GO:1903375 9.55 NRP1 SEMA3A
43 gonadotrophin-releasing hormone neuronal migration to the hypothalamus GO:0021828 9.54 NRP1 SEMA3A
44 regulation of axon extension involved in axon guidance GO:0048841 9.52 NRP1 SEMA3A
45 regulation of retinal ganglion cell axon guidance GO:0090259 9.51 NRP1 VEGFA
46 vascular endothelial growth factor signaling pathway GO:0038084 9.5 KDR NRP1 VEGFA
47 motor neuron migration GO:0097475 9.48 NRP1 VEGFA
48 positive regulation of retinal ganglion cell axon guidance GO:1902336 9.46 NRP1 VEGFA
49 positive regulation of endothelial cell proliferation GO:0001938 9.46 FGF2 KDR NRP1 VEGFA
50 VEGF-activated neuropilin signaling pathway GO:0038190 9.43 NRP1 VEGFA

Molecular functions related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.63 GAPDH GFAP KDR PGR TFRC VEGFA
2 heparin binding GO:0008201 9.5 FGF2 NRP1 VEGFA
3 integrin binding GO:0005178 9.26 FGF2 KDR
4 vascular endothelial growth factor-activated receptor activity GO:0005021 8.96 KDR NRP1
5 vascular endothelial growth factor binding GO:0038085 8.62 KDR NRP1

Sources for Angiomatous Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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