MCID: ANG061
MIFTS: 32

Angular Cheilitis

Categories: Oral diseases

Aliases & Classifications for Angular Cheilitis

MalaCards integrated aliases for Angular Cheilitis:

Name: Angular Cheilitis 12 29 15 73
Cheilosis 12 73
Commissural Cheilitis 12
Angular Stomatitis 12
Angular Cheilosis 12
Cheilitis 44

Classifications:



External Ids:

Disease Ontology 12 DOID:0060312
ICD10 33 K13.0
MeSH 44 D002613
NCIt 50 C79545

Summaries for Angular Cheilitis

Disease Ontology : 12 A cheilitis characterized by inflammation of one or both of the corners of the mouth.

MalaCards based summary : Angular Cheilitis, also known as cheilosis, is related to cheilitis glandularis and actinic cheilitis. An important gene associated with Angular Cheilitis is TMEM79 (Transmembrane Protein 79), and among its related pathways/superpathways are Synthesis of substrates in N-glycan biosythesis and Glucose / Energy Metabolism. Affiliated tissues include skin, and related phenotype is growth/size/body region.

Wikipedia : 76 Angular cheilitis (AC) is inflammation of one or both corners of the mouth. Often the corners are red... more...

Related Diseases for Angular Cheilitis

Diseases related to Angular Cheilitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 21)
# Related Disease Score Top Affiliating Genes
1 cheilitis glandularis 12.4
2 actinic cheilitis 11.6
3 ichthyosis follicularis atrichia photophobia syndrome 11.2
4 plummer vinson syndrome 10.9
5 cheilitis 10.8
6 iron metabolism disease 10.1
7 macroglossia 10.1
8 cutaneous leishmaniasis 10.0
9 leishmaniasis 10.0
10 pemphigus vulgaris, familial 9.9
11 crohn's disease 9.9
12 pemphigus vulgaris 9.9
13 denture stomatitis 9.9
14 oral candidiasis 9.9
15 candidiasis 9.9
16 dermatitis 9.9
17 contact dermatitis 9.9
18 pemphigus 9.9
19 stomatitis 9.9
20 lipodystrophy, familial partial, type 2 9.2 GFPT1 GFPT2
21 pancreatic steatorrhea 9.0 GFPT1 GFPT2

Graphical network of the top 20 diseases related to Angular Cheilitis:



Diseases related to Angular Cheilitis

Symptoms & Phenotypes for Angular Cheilitis

MGI Mouse Phenotypes related to Angular Cheilitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.02 CDKN2C GFPT2 SAT1 TF TMEM79

Drugs & Therapeutics for Angular Cheilitis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Dental Hygienist Support Promotes Good Oral Health in Nursing Homes Completed NCT02676453 Not Applicable

Search NIH Clinical Center for Angular Cheilitis

Cochrane evidence based reviews: cheilitis

Genetic Tests for Angular Cheilitis

Genetic tests related to Angular Cheilitis:

# Genetic test Affiliating Genes
1 Angular Cheilitis 29

Anatomical Context for Angular Cheilitis

MalaCards organs/tissues related to Angular Cheilitis:

41
Skin

Publications for Angular Cheilitis

Articles related to Angular Cheilitis:

(show all 49)
# Title Authors Year
1
Hyaluronic acid dermal fillers in the management of recurrent angular cheilitis: A case report. ( 29733533 )
2018
2
Angular cheilitis: A clinical and microbial study. ( 29256466 )
2017
3
Recurrent angular cheilitis after secukinumab injections. ( 28620989 )
2017
4
Recurrent angular cheilitis in a patient with mucocutaneous pemphigus vulgaris. ( 25788140 )
2015
5
Comparative study on the microbiological features of angular cheilitis in HIV seropositive and HIV seronegative patients from South India. ( 24574650 )
2013
6
Fissures near mouth. Angular cheilitis (perlA"che). ( 24482867 )
2013
7
Angular cheilitis: a maligned condition. ( 24053003 )
2013
8
Soreness around mouth. Contact dermatitis and angular cheilitis (perlA"che). ( 24482868 )
2013
9
How do I manage a patient with angular cheilitis? ( 23763743 )
2013
10
Angular cheilitis after paroxetine treatment. ( 22217958 )
2012
11
Angular cheilitis, part 1: local etiologies. ( 21838086 )
2011
12
Angular cheilitis, part 2: nutritional, systemic, and drug-related causes and treatment. ( 21877503 )
2011
13
Organised angular cheilitis as the initial sign of Crohn's disease in two children. ( 21243320 )
2011
14
Oral candidiasis and angular cheilitis. ( 20597942 )
2010
15
The clinical features of angular cheilitis occurring during orthodontic treatment: a multi-centre observational study. ( 20567030 )
2010
16
Angular cheilitis occurring during orthodontic treatment: a case series. ( 19074360 )
2008
17
Prosthodontic management of angular cheilitis and persistent drooling: a case report. ( 18018392 )
2007
18
Dermacase. Angular cheilitis. ( 17882763 )
2007
19
Clinical inquiries. What is angular cheilitis and how is it treated? ( 15865910 )
2005
20
Nickel-induced angular cheilitis due to orthodontic braces. ( 12868984 )
2003
21
Mustache grooming associated with angular cheilitis. ( 11764118 )
2000
22
Angular cheilitis after tonsillectomy. ( 10472460 )
1999
23
Acquired linear anetoderma following angular cheilitis. ( 9666860 )
1998
24
Angular cheilitis in HIV-infected patients from Spain: a common Candida-associated oral lesion. ( 11507473 )
1997
25
Angular cheilitis: a case for the oral physician? ( 8941789 )
1995
26
Clinical, microbiological and ultrastructural features of angular cheilitis lesions in Southern Chinese. ( 7553380 )
1995
27
Case #5. Angular cheilitis. ( 1410625 )
1992
28
Angular cheilitis in a group of Sri Lankan adults: a clinical and microbiologic study. ( 2061855 )
1991
29
Oral medicine in practice: angular cheilitis. ( 2069827 )
1991
30
Oral medicine in practice: angular cheilitis. ( 2775569 )
1989
31
Phenotypic characterization of mononuclear cells and class II antigen expression in angular cheilitis infected by Candida albicans or Staphylococcus aureus. ( 2468179 )
1989
32
'Oral medicine in practice: angular cheilitis'. ( 2610751 )
1989
33
Treatment of angular cheilitis. The significance of microbial analysis, antimicrobial treatment, and interfering factors. ( 3063051 )
1988
34
Recurrence of angular cheilitis. ( 3166200 )
1988
35
Angular cheilitis: a clinical and microbial study. ( 3088236 )
1986
36
Recurrent angular cheilitis caused by dental flossing. ( 3722500 )
1986
37
Antibiotic sensitivity and phage typing of Staphylococcus aureus isolated from non-hospitalized patients with angular cheilitis. ( 6085101 )
1984
38
Angular cheilitis--a bacterial infection. ( 6955524 )
1982
39
Angular cheilitis. ( 6938926 )
1981
40
Iron deficiency: an overlooked predisposing factor in angular cheilitis. ( 292723 )
1979
41
Sensitivity to miconazole of micro-organisms associated with angular cheilitis. ( 346034 )
1978
42
Angular Cheilitis. ( 319959 )
1977
43
Management of patients with angular cheilitis. ( 271135 )
1977
44
The microbiology of angular cheilitis. ( 1067101 )
1976
45
A surgical treatment of angular cheilitis. ( 5568636 )
1971
46
Denture sore mouth and angular cheilitis--a case report and review of literature. ( 5268428 )
1970
47
Angular cheilitis and iron deficiency. ( 5264769 )
1969
48
Denture stomatitis and angular cheilitis in patients receiving long-term tetracycline therapy. ( 5239488 )
1968
49
Angular cheilitis caused by overclosure of the jaws. ( 5236394 )
1967

Variations for Angular Cheilitis

Expression for Angular Cheilitis

Search GEO for disease gene expression data for Angular Cheilitis.

Pathways for Angular Cheilitis

GO Terms for Angular Cheilitis

Biological processes related to Angular Cheilitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein N-linked glycosylation GO:0006487 9.43 GFPT1 GFPT2
2 glutamine metabolic process GO:0006541 9.4 GFPT1 GFPT2
3 energy reserve metabolic process GO:0006112 9.37 GFPT1 GFPT2
4 UDP-N-acetylglucosamine biosynthetic process GO:0006048 9.32 GFPT1 GFPT2
5 fructose 6-phosphate metabolic process GO:0006002 9.26 GFPT1 GFPT2
6 UDP-N-acetylglucosamine metabolic process GO:0006047 9.16 GFPT1 GFPT2
7 carbohydrate derivative metabolic process GO:1901135 8.96 GFPT1 GFPT2
8 carbohydrate derivative biosynthetic process GO:1901137 8.62 GFPT1 GFPT2

Molecular functions related to Angular Cheilitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transaminase activity GO:0008483 9.16 GFPT1 GFPT2
2 carbohydrate derivative binding GO:0097367 8.96 GFPT1 GFPT2
3 glutamine-fructose-6-phosphate transaminase (isomerizing) activity GO:0004360 8.62 GFPT1 GFPT2

Sources for Angular Cheilitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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