MCID: ANM002
MIFTS: 26

Animal Phobia

Categories: Mental diseases

Aliases & Classifications for Animal Phobia

MalaCards integrated aliases for Animal Phobia:

Name: Animal Phobia 12 15 17
Zoophobia 12 70
Fear of Animals 12

Classifications:



External Ids:

Disease Ontology 12 DOID:600
NCIt 50 C35273
SNOMED-CT 67 54307006
UMLS 70 C0233711

Summaries for Animal Phobia

Disease Ontology : 12 A specific phobia that involves a fear caused by the presence or thought of a specific animal that poses little or no danger at all.

MalaCards based summary : Animal Phobia, also known as zoophobia, is related to phobia, specific and separation anxiety disorder. An important gene associated with Animal Phobia is HEXA (Hexosaminidase Subunit Alpha). The drug Complement System Proteins has been mentioned in the context of this disorder. Affiliated tissues include eye and amygdala, and related phenotype is renal/urinary system.

Wikipedia : 73 Zoophobia or animal phobia is a class of specific phobias to particular animals, or an irrational fear... more...

Related Diseases for Animal Phobia

Diseases related to Animal Phobia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 39)
# Related Disease Score Top Affiliating Genes
1 phobia, specific 30.4 SLC6A4 OXT
2 separation anxiety disorder 30.0 SLC6A4 OXT
3 agoraphobia 29.6 SLC6A4 PTK7
4 social phobia 29.4 SLC6A4 PTK7 OXT
5 obsessive-compulsive disorder 29.3 SLC6A4 PTK7 OXT
6 inhibited male orgasm 10.1 SLC6A4 OXT
7 somatization disorder 10.1 SLC6A4 OXT
8 psychosexual disorder 10.1 SLC6A4 OXT
9 sexual disorder 10.1 SLC6A4 OXT
10 paraphilia disorder 10.1 SLC6A4 OXT
11 intermittent explosive disorder 10.1 SLC6A4 OXT
12 dissociative disorder 10.1 SLC6A4 OXT
13 neurotic disorder 10.1 SLC6A4 OXT
14 hypochondriasis 10.1 SLC6A4 OXT
15 adjustment disorder 10.1 SLC6A4 OXT
16 acute stress disorder 10.1 SLC6A4 OXT
17 premature ejaculation 10.1 SLC6A4 OXT
18 body dysmorphic disorder 10.1 SLC6A4 OXT
19 serotonin syndrome 10.1 SLC6A4 OXT
20 alexithymia 10.1 SLC6A4 OXT
21 oppositional defiant disorder 10.1 SLC6A4 OXT
22 antisocial personality disorder 10.0 SLC6A4 OXT
23 endogenous depression 10.0 SLC6A4 OXT
24 postpartum depression 10.0 SLC6A4 OXT
25 mental depression 10.0 SLC6A4 OXT
26 bulimia nervosa 10.0 SLC6A4 OXT
27 metachromatic leukodystrophy 10.0 SLC6A4 HEXA
28 myasthenic syndrome, congenital, 1a, slow-channel 10.0 TCF20 OXT
29 asperger syndrome 10.0 SLC6A4 OXT
30 kagami-ogata syndrome 9.9 SLC6A4 OXT
31 specific developmental disorder 9.9 SLC6A4 OXT
32 panic disorder 9.9
33 pervasive developmental disorder 9.8 SLC6A4 OXT
34 anorexia nervosa 9.7 SLC6A4 OXT
35 constipation 9.7 TCF20 SLC6A4 NALCN
36 phobic disorder 9.7 SLC6A4 PTK7 OXT
37 attention deficit-hyperactivity disorder 9.7 TCF20 SLC6A4 OXT
38 anxiety 9.6 SLC6A4 PTK7 OXT
39 disease of mental health 9.0 TCF20 SLC6A4 PTK7 OXT NALCN

Graphical network of the top 20 diseases related to Animal Phobia:



Diseases related to Animal Phobia

Symptoms & Phenotypes for Animal Phobia

MGI Mouse Phenotypes related to Animal Phobia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 8.92 HEXA NALCN OXT PTK7

Drugs & Therapeutics for Animal Phobia

Drugs for Animal Phobia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Complement System Proteins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 In Vivo Versus Augmented Reality Exposure for Small Animal Phobia Treatment: A Randomized Controlled Trial Completed NCT01361074
2 Bringing Exposure Therapy for Small Animal Phobias (Spiders and Snakes) to Real-Life Context With Augmented Reality Recruiting NCT03649347
3 Improving the Exposure Therapy Through Projection-based Augmented Reality for the Treatment of Cockroach Phobia: A Multiple-baseline Single Case Study Not yet recruiting NCT04553120
4 Enhancing Exposure Therapy for Spider Phobia With the Use of Threat-Relevant and Threat-Irrelevant Opposite Actions Terminated NCT02905279
5 EMDR (Eye Movement Desensitization and Reprocessing) in the Treatment of Specific Phobia. A Randomised Controlled Trial. Withdrawn NCT00184145

Search NIH Clinical Center for Animal Phobia

Genetic Tests for Animal Phobia

Anatomical Context for Animal Phobia

MalaCards organs/tissues related to Animal Phobia:

40
Eye, Amygdala

Publications for Animal Phobia

Articles related to Animal Phobia:

(show top 50) (show all 54)
# Title Authors PMID Year
1
Neuronal Correlates of Small Animal Phobia in Human Subjects through fMRI: The Role of the Number and Proximity of Stimuli. 61
33810230 2021
2
The Effect of Personality Traits on Cognitive Behavioral Therapy Outcomes in Student Pharmacists with Rat Phobia: A Randomized Clinical Trial. 61
33487789 2021
3
Assessing the role of the amygdala in fear of pain: Neural activation under threat of shock. 61
32791350 2020
4
Scary and nasty beasts: Self-reported fear and disgust of common phobic animals. 61
31183857 2020
5
Evaluation of the Effectiveness of One- and Multi-Session Exposure-Based Treatments in Reducing Biological and Psychological Responses to Rat Phobia Among Students. 61
32848483 2020
6
Virtual Reality, Augmented Reality, and In Vivo Exposure Therapy: A Preliminary Comparison of Treatment Efficacy in Small Animal Phobia. 61
30335525 2019
7
[Examination of shortened version of spider phobia and snake phobia questionnaire on Hungarian sample]. 61
31074419 2019
8
Screening for childhood anxiety: A meta-analysis of the screen for child anxiety related emotional disorders. 61
30081293 2018
9
Anxiety Disorders in Old Age: Psychiatric Comorbidities, Quality of Life, and Prevalence According to Age, Gender, and Country. 61
29031568 2018
10
Psychophysiological and self-reported reactivity associated with social anxiety and public speaking fear symptoms: Effects of fear versus distress. 61
28599192 2017
11
Measuring Anxiety in Children: The Importance of Separate Mother and Father Reports. 61
28989266 2017
12
Pure animal phobia is more specific than other specific phobias: epidemiological evidence from the Zurich Study, the ZInEP and the PsyCoLaus. 61
27001383 2016
13
In Vivo versus Augmented Reality Exposure in the Treatment of Small Animal Phobia: A Randomized Controlled Trial. 61
26886423 2016
14
Brain activity associated with illusory correlations in animal phobia. 61
25411452 2015
15
The structure of genetic and environmental risk factors for fears and phobias. 61
24384457 2014
16
Cortico-limbic responses to masked affective faces across ptsd, panic disorder, and specific phobia. 61
23861215 2014
17
Fear processing in dental phobia during crossmodal symptom provocation: an fMRI study. 61
24738049 2014
18
How technology influences the therapeutic process: evaluation of the patient-therapist relationship in augmented reality exposure therapy and in vivo exposure therapy. 61
23410820 2013
19
Decision making in the pathway from genes to psychiatric and substance use disorders. 61
23128152 2013
20
Specific fear modulates attentional selectivity during visual search: electrophysiological insights from the N2pc. 61
23252841 2013
21
Suicidal risk factors of recurrent major depression in Han Chinese women. 61
24312196 2013
22
Patterns of co-morbidity with anxiety disorders in Chinese women with recurrent major depression. 61
22126712 2012
23
The structure of genetic and environmental risk factors for phobias in women. 61
21211096 2011
24
How specific is specific phobia? Different neural response patterns in two subtypes of specific phobia. 61
21316468 2011
25
Late cortical positivity and cardiac responsitivity in female dental phobics when exposed to phobia-relevant pictures. 61
21238507 2011
26
Anxiety sensitivity correlates with two indices of right anterior insula structure in specific animal phobia. 61
21132846 2010
27
The prevalence of specific phobia and associated co-morbid features in children and adolescents. 61
20439148 2010
28
Functional MRI study of specific animal phobia using an event-related emotional counting stroop paradigm. 61
19434621 2009
29
Telepsychology and self-help: the treatment of phobias using the internet. 61
18991528 2008
30
Disgust sensitivity and psychopathological symptoms in non-clinical children. 61
17433251 2008
31
Attention bias in children of patients with panic disorder. 61
18337628 2008
32
Low extraversion and high neuroticism as indices of genetic and environmental risk for social phobia, agoraphobia, and animal phobia. 61
17974937 2007
33
A population-based twin study of the relationship between neuroticism and internalizing disorders. 61
16648327 2006
34
The structure of genetic and environmental risk factors for anxiety disorders in men and women. 61
15699295 2005
35
A magnetic resonance imaging study of cortical thickness in animal phobia. 61
15110739 2004
36
Functional magnetic resonance imaging evidence for a lack of striatal dysfunction during implicit sequence learning in individuals with animal phobia. 61
14702252 2004
37
Amygdala and insular responses to emotionally valenced human faces in small animal specific phobia. 61
14625149 2003
38
Priming panic interpretations in children of patients with panic disorder. 61
12405521 2002
39
Disgust sensitivity, trait anxiety and anxiety disorders symptoms in normal children. 61
10472712 1999
40
The structure of specific phobia symptoms among children and adolescents. 61
10458049 1999
41
Fears and phobias: reliability and heritability. 61
10405076 1999
42
Psychopathology in children of patients with panic disorder or animal phobia. 61
9561550 1998
43
Eye movement desensitisation and reprocessing versus exposure in vivo. A single-session crossover study of spider-phobic children. 61
9328502 1997
44
Parental history, aversive exposure and the development of snake and spider phobia in women. 61
9009040 1997
45
Gender and age differences in the prevalence of specific fears and phobias. 61
8561762 1996
46
Major depression and phobias: the genetic and environmental sources of comorbidity. 61
8332653 1993
47
Familial resemblances in disgust sensitivity and animal phobias. 61
8417727 1993
48
The genetic epidemiology of phobias in women. The interrelationship of agoraphobia, social phobia, situational phobia, and simple phobia. 61
1558461 1992
49
A test of a disease-avoidance model of animal phobias. 61
2012593 1991
50
Relaxation therapy, desensitization, and the treatment of anxiety-based disorders. 61
41849 1979

Variations for Animal Phobia

Expression for Animal Phobia

Search GEO for disease gene expression data for Animal Phobia.

Pathways for Animal Phobia

GO Terms for Animal Phobia

Biological processes related to Animal Phobia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane transport GO:0055085 9.58 SLC6A4 SLC35B2 NALCN
2 response to estradiol GO:0032355 9.37 SLC6A4 OXT
3 sodium ion transmembrane transport GO:0035725 9.32 SLC6A4 NALCN
4 memory GO:0007613 9.26 SLC6A4 OXT
5 cellular response to retinoic acid GO:0071300 9.16 SLC6A4 PTK7
6 social behavior GO:0035176 8.96 SLC6A4 OXT
7 sperm ejaculation GO:0042713 8.62 SLC6A4 OXT

Sources for Animal Phobia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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