MCID: ANS003
MIFTS: 40

Anisakiasis

Categories: Gastrointestinal diseases, Immune diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Anisakiasis

MalaCards integrated aliases for Anisakiasis:

Name: Anisakiasis 12 74 52 58 54 3 43 15 17 71 32
Infection by Anisakis Larva 12 71
Anisakis Infection 52 3
Pseudoterranova Infection 52

Characteristics:

Orphanet epidemiological data:

58
anisakiasis
Prevalence: 1-9/100000 (Japan),1-9/1000000 (Worldwide); Age of onset: Adolescent,Adult,Childhood,Elderly; Age of death: normal life expectancy;

Classifications:

Orphanet: 58  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:7033
ICD9CM 34 127.1
MeSH 43 D017129
NCIt 49 C128393
SNOMED-CT 67 442652006
ICD10 32 B81.0
MESH via Orphanet 44 D017129
ICD10 via Orphanet 33 B81.0
UMLS via Orphanet 72 C0162576 C2711591
Orphanet 58 ORPHA1070
UMLS 71 C0162576 C2711266

Summaries for Anisakiasis

Disease Ontology : 12 A parasitic helminthiasis infectious disease that results in infection located in intestinal mucosa with larvae of the nematodes transmitted by ingestion of raw or poorly cooked saltwater fish, has material basis in Anisakis simplex or has material basis in Pseudoterranova decipiens and has symptom abdominal pain, has symptom nausea and vomiting. Invasive anisakiasis results in the infection of omentum, pancreas, liver, and lung.

MalaCards based summary : Anisakiasis, also known as infection by anisakis larva, is related to urticaria and parasitic helminthiasis infectious disease, and has symptoms including abdominal pain and nausea. An important gene associated with Anisakiasis is RNASE3 (Ribonuclease A Family Member 3), and among its related pathways/superpathways are Primary immunodeficiency and Cardiac muscle contraction. The drugs Antibodies and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include intestinal mucosa, liver and colon.

CDC : 3 Anisakiasis, or herring worm disease, is a parasitic disease caused by nematodes (worms) that attach to the wall of the esophagus, stomach, or intestine. The best ways to prevent this disease is to avoid eating raw or undercooked fish or squid.

Wikipedia : 74 Anisakis is a genus of parasitic nematodes that have lifecycles involving fish and marine mammals. They... more...

Related Diseases for Anisakiasis

Diseases related to Anisakiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 147)
# Related Disease Score Top Affiliating Genes
1 urticaria 30.9 RNASE3 IGHE CD40LG
2 parasitic helminthiasis infectious disease 29.9 TES RNASE3 CD40LG
3 toxocariasis 29.9 TES RNASE3 IGHE CD40LG
4 intestinal obstruction 10.6
5 appendicitis 10.5
6 atopic keratoconjunctivitis 10.4 RNASE3 IGHE
7 exercise-induced anaphylaxis 10.4 IGHE CD79A
8 hypereosinophilic syndrome 10.4
9 vernal conjunctivitis 10.4 RNASE3 IGHE
10 cough variant asthma 10.4 RNASE3 IGHE
11 vernal keratoconjunctivitis 10.4 RNASE3 IGHE
12 intrinsic asthma 10.4 RNASE3 IGHE
13 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.4
14 ileitis 10.4
15 gastric ulcer 10.4
16 angioedema 10.4
17 ileus 10.4
18 clonorchiasis 10.4 IGHE CD79A
19 ocular cicatricial pemphigoid 10.4 RNASE3 CD79A
20 intussusception 10.4
21 peritonitis 10.4
22 kimura disease 10.4 RNASE3 IGHE
23 strongyloidiasis 10.4 IGHE CD79A
24 chronic conjunctivitis 10.4 RNASE3 IGHE
25 latex allergy 10.3 RNASE3 IGHE
26 urinary schistosomiasis 10.3 RNASE3 IGHE
27 episodic angioedema with eosinophilia 10.3 IGHE CD40LG
28 gastritis 10.2
29 hemorrhagic fever-renal syndrome 10.2 CD79A CD40LG
30 c1q nephropathy 10.2 CD79A CD40LG
31 hilar lung carcinoma 10.2 CD79A CD40LG
32 lung hilum cancer 10.2 CD79A CD40LG
33 milk allergy 10.2 RNASE3 IGHE CD79A
34 cryofibrinogenemia 10.2 CD79A CD40LG
35 monoclonal paraproteinemia 10.2 CD79A CD40LG
36 viral laryngitis 10.2 RNASE3 CD40LG
37 cerebral lymphoma 10.2 CD79A CD40LG
38 pollen allergy 10.2 RNASE3 IGHE
39 selective igg deficiency disease 10.2 CD79A CD40LG
40 alpha chain disease 10.2 CD79A CD40LG
41 maxillary sinusitis 10.2 RNASE3 CD40LG
42 congenital syphilis 10.2 CD79A CD40LG
43 secondary syphilis 10.2 CD79A CD40LG
44 heavy chain disease 10.2 CD79A CD40LG
45 vasomotor rhinitis 10.2 RNASE3 CD40LG
46 paragonimiasis 10.2 TES RNASE3 IGHE
47 immunoglobulin a deficiency 1 10.2 CD79A CD40LG
48 pustulosis palmaris et plantaris 10.2 CD79A CD40LG
49 parotitis 10.2 CD79A CD40LG
50 calciphylaxis 10.2 CD79A CD40LG

Graphical network of the top 20 diseases related to Anisakiasis:



Diseases related to Anisakiasis

Symptoms & Phenotypes for Anisakiasis

Symptoms:

12
  • abdominal pain
  • nausea

Drugs & Therapeutics for Anisakiasis

Drugs for Anisakiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antibodies
2 Immunologic Factors
3 Immunoglobulins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Protists and Nematodes Fish Parasites: From Their Circulation in Ecosystems to Their Impact on Human Health - Prevalence of Fish Allergy in Occupational Settings. Completed NCT02661074
2 Protists and Nematodes Fish Parasites: From Their Circulation in Ecosystems to Their Impact on Human Health - Role of Anisakidae and/or Fish Flesh Antigens in Fish Allergies. Completed NCT02666092

Search NIH Clinical Center for Anisakiasis

Cochrane evidence based reviews: anisakiasis

Genetic Tests for Anisakiasis

Anatomical Context for Anisakiasis

The Foundational Model of Anatomy Ontology organs/tissues related to Anisakiasis:

19
Intestinal Mucosa

MalaCards organs/tissues related to Anisakiasis:

40
Liver, Colon, Lung, Pancreas, Small Intestine, Testes, Lymph Node

Publications for Anisakiasis

Articles related to Anisakiasis:

(show top 50) (show all 629)
# Title Authors PMID Year
1
Novel sequences and epitopes of diagnostic value derived from the Anisakis simplex Ani s 7 major allergen. 61 54
18186812 2008
2
Measurement of serum levels of eosinophil cationic protein in the diagnosis of acute gastrointestinal anisakiasis. 54 61
12848764 2003
3
Specific IgE determination to Ani s 1, a major allergen from Anisakis simplex, is a useful tool for diagnosis. 61 54
12141725 2002
4
Serum CD23 is not altered in gastroallergic anisakiasis, but correlates with the production of specific IgE and the amount of polyclonal stimulation. 54 61
11576082 2001
5
Immunoblot analysis of serum IgG, IgA and IgE responses against larval excretory-secretory antigens of Anisakis simplex in patients with gastric anisakiasis. 61 54
2283472 1990
6
Effect of freezing on the metabolic status of L3 larvae of Anisakis simplex s. s. 61
32247867 2020
7
Anisakis and Hysterothylacium species in Mediterranean and North-East Atlantic fishes commonly consumed in Spain: Epidemiological, molecular and morphometric discriminant analysis. 61
32361053 2020
8
The Selection of Reliable Reference Genes for RT-qPCR Analysis of Anisakis simplex Sensu Stricto Gene Expression from Different Developmental Stages. 61
32488545 2020
9
First case of human anisakiasis in Poland. 61
32044432 2020
10
Anisakiasis: The Importance of Prevention and the Role of Diet Therapy in Allergic Patients. 61
32392567 2020
11
A Case of Anaphylaxis with Mild Abdominal Pain Due to Gastroallergic Anisakiasis. 61
32289306 2020
12
Comparison of risk factors between human intestinal and gastric Anisakiasis. 61
31730806 2020
13
[Investigation on the risk of of Anisakis infection among high - risk populations along the coastal areas of Jiangsu Province]. 61
32468791 2020
14
Posterior Mediastinitis Caused by Esophageal Anisakiasis. 61
32360812 2020
15
Gastric Anisakiasis. 61
32430110 2020
16
Comparative Transcriptomics Reveals Clues for Differences in Pathogenicity between Hysterothylacium aduncum, Anisakissimplex sensu stricto and Anisakis pegreffii. 61
32197414 2020
17
Usefulness of Ultrasound in the Diagnosis of Intestinal Anisakiasis. 61
32154595 2020
18
Asymptomatic Anisakiasis in a Patient with Crohn's Disease. 61
32142008 2020
19
Acute Anisakiasis: Pharmacological Evaluation of Various Drugs in an Animal Model. 61
32107679 2020
20
Recent increase of ulcerative lesions caused by Anisakis spp. in cetaceans from the north-east Atlantic. 61
32100663 2020
21
Anisakiasis in a Canadian patient with incarcerated epigastric hernia. 61
32140413 2020
22
Validation of a Commercial Loop-Mediated Isothermal Amplification (LAMP) Assay for the Rapid Detection of Anisakis spp. DNA in Processed Fish Products. 61
31963107 2020
23
Anisakis Sensitization in the Croatian fish processing workers: Behavioral instead of occupational risk factors? 61
31986138 2020
24
Occurrence of Anisakis and Hysterothylacium Nematodes in Atlantic Chub Mackerels from Libyan Coasts. 61
31708677 2019
25
Anisakid Larvae from Anchovies in the South Coast of Korea. 61
31914524 2019
26
A Case Report of Adhesional Small Bowel Obstruction Caused by Extraintestinal Anisakiasis. 61
31685366 2019
27
Differential Cleaving of Specific Substrates for Cathepsin-Like Activity Shows Cysteine and Serine Protease Activities and a Differential Profile Between Anisakis simplex s.s. and Anisakis pegreffii, Sibling Species Major Etiologic Agents of Anisakiasis. 61
31215796 2019
28
Functional Ultrastructure of the Excretory Gland Cell in Zoonotic Anisakids (Anisakidae, Nematoda). 61
31744245 2019
29
Genome-wide analysis of Anisakis simplex sensu lato: the role of carbohydrate metabolism genes in the parasite's development. 61
31560928 2019
30
Occurrence of Anisakis pegreffii (Nematoda: Anisakidae) Larvae in Imported John Dory (Zeus faber) from Senegalese Coast Sold in Turkish Supermarkets. 61
31172352 2019
31
Adult intussusception caused by colonic anisakis: A case report. 61
31559289 2019
32
Asymptomatic Gastric and Colonic Anisakiasis Detected Simultaneously. 61
30996191 2019
33
Clinical and Endoscopic Features of Colonic Anisakiasis in Korea. 61
31533408 2019
34
Anisakis Nematodes in Fish and Shellfish- from infection to allergies. 61
31338296 2019
35
Differential proteolytic activity in Anisakis simplex s.s. and Anisakis pegreffii, two sibling species from the complex Anisakis simplex s.l., major etiological agents of anisakiasis. 61
30995435 2019
36
Gastric anisakiasis presenting as a vanishing tumor. 61
31312584 2019
37
Gastro-allergic anisakiasis: The first case reported in Colombia and a literature review 61
31529811 2019
38
Easy Detection and Fast Removal of Gastric Anisakis during Narrow-Band Imaging Endoscopy with L-Menthol Administration. 61
31427913 2019
39
Interplay between proinflammatory cytokines, miRNA, and tissue lesions in Anisakis-infected Sprague-Dawley rats. 61
31091271 2019
40
'Tingling throat syndrome' as asymptomatic anisakiasis following conveyor belt sushi consumption in Tokyo. 61
30904673 2019
41
Multidisciplinary approach in study of the zoonotic Anisakis larval infection in the blue mackerel (Scomber australasicus) and the largehead hairtail (Trichiurus lepturus) in Northern Taiwan. 61
31182381 2019
42
Genes expression and in silico studies of functions of trehalases, a highly dispersed Anisakis simplex s. l. specific gene family. 61
30779983 2019
43
Occurrence of larval ascaridoid nematodes in the Argentinean short-finned squid Illex argentinus from the Southwest Atlantic Ocean (off Falkland Islands). 61
30870722 2019
44
Molecular Identification of Anisakis Larvae Extracted by Gastrointestinal Endoscopy from Health Check-up Patients in Korea. 61
31104416 2019
45
[Anisakiasis as differential diagnosis of acute abdominal pain at the emergencydepartment]. 61
31333235 2019
46
Gastric anisakiasis after eating raw salmon. 61
30482477 2019
47
Prevalence of anisakid parasites in fish collected from Apulia region (Italy) and quantification of nematode larvae in flesh. 61
30599456 2019
48
Anisakiasis in the Small Intestine with Excessive Bleeding That Was Difficult to Diagnose Endoscopically. 61
30146603 2019
49
Gastric anisakiasis: a rare cause of abdominal pain. 61
30680902 2019
50
Hepatic anisakiasis mimicking metastatic liver tumour. 61
31238201 2019

Variations for Anisakiasis

Expression for Anisakiasis

Search GEO for disease gene expression data for Anisakiasis.

Pathways for Anisakiasis

Pathways related to Anisakiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.74 CD79A CD40LG
2 10.74 TPM4 TPM2 MT-CO2
3 10.51 TPM4 TPM2

GO Terms for Anisakiasis

Cellular components related to Anisakiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle thin filament tropomyosin GO:0005862 8.62 TPM4 TPM2

Biological processes related to Anisakiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 8.96 TPM4 TPM2
2 B cell proliferation GO:0042100 8.62 CD79A CD40LG

Sources for Anisakiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....