MCID: ANS003
MIFTS: 39

Anisakiasis

Categories: Gastrointestinal diseases, Immune diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Anisakiasis

MalaCards integrated aliases for Anisakiasis:

Name: Anisakiasis 12 74 52 58 54 3 43 15 17 71 32
Infection by Anisakis Larva 12 71
Anisakis Infection 52 3
Pseudoterranova Infection 52

Characteristics:

Orphanet epidemiological data:

58
anisakiasis
Prevalence: 1-9/100000 (Japan),1-9/1000000 (Worldwide); Age of onset: Adolescent,Adult,Childhood,Elderly; Age of death: normal life expectancy;

Classifications:

Orphanet: 58  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:7033
ICD9CM 34 127.1
MeSH 43 D017129
NCIt 49 C128393
SNOMED-CT 67 32183007
ICD10 32 B81.0
MESH via Orphanet 44 D017129
ICD10 via Orphanet 33 B81.0
UMLS via Orphanet 72 C0162576 C2711591
Orphanet 58 ORPHA1070
UMLS 71 C0162576 C2711266

Summaries for Anisakiasis

Disease Ontology : 12 A parasitic helminthiasis infectious disease that results in infection located in intestinal mucosa with larvae of the nematodes transmitted by ingestion of raw or poorly cooked saltwater fish, has material basis in Anisakis simplex or has material basis in Pseudoterranova decipiens and has symptom abdominal pain, has symptom nausea and vomiting. Invasive anisakiasis results in the infection of omentum, pancreas, liver, and lung.

MalaCards based summary : Anisakiasis, also known as infection by anisakis larva, is related to allergic hypersensitivity disease and toxocariasis, and has symptoms including abdominal pain and nausea. An important gene associated with Anisakiasis is RNASE3 (Ribonuclease A Family Member 3), and among its related pathways/superpathways are Cardiac muscle contraction and Smooth Muscle Contraction. The drugs Immunologic Factors and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include intestinal mucosa, liver and colon.

CDC : 3 Anisakiasis, or herring worm disease, is a parasitic disease caused by nematodes (worms) that attach to the wall of the esophagus, stomach, or intestine. The best ways to prevent this disease is to avoid eating raw or undercooked fish or squid.

Wikipedia : 74 Anisakis is a genus of parasitic nematodes that have lifecycles involving fish and marine mammals. They... more...

Related Diseases for Anisakiasis

Diseases related to Anisakiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)
# Related Disease Score Top Affiliating Genes
1 allergic hypersensitivity disease 30.4 RNASE3 IGHE CD79A
2 toxocariasis 30.3 TES RNASE3 IGHE
3 intestinal obstruction 10.6
4 urticaria 10.6
5 appendicitis 10.5
6 hypereosinophilic syndrome 10.4
7 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.4
8 ileitis 10.4
9 gastric ulcer 10.4
10 angioedema 10.4
11 ileus 10.4
12 immunoglobulin g deficiency 10.4 IGHE CD79A
13 exercise-induced anaphylaxis 10.4 IGHE CD79A
14 atopic keratoconjunctivitis 10.4 RNASE3 IGHE
15 ocular toxoplasmosis 10.4 IGHE CD79A
16 vernal conjunctivitis 10.4 RNASE3 IGHE
17 cough variant asthma 10.4 RNASE3 IGHE
18 intussusception 10.4
19 peritonitis 10.4
20 vernal keratoconjunctivitis 10.3 RNASE3 IGHE
21 immunodeficiency with hyper-igm, type 1 10.3 IGHE CD79A
22 intrinsic asthma 10.3 RNASE3 IGHE
23 hydrops, lactic acidosis, and sideroblastic anemia 10.3
24 clonorchiasis 10.3 IGHE CD79A
25 chronic conjunctivitis 10.3 RNASE3 IGHE
26 ocular cicatricial pemphigoid 10.3 RNASE3 CD79A
27 kimura disease 10.3 RNASE3 IGHE
28 strongyloidiasis 10.3 IGHE CD79A
29 urinary schistosomiasis 10.3 RNASE3 IGHE
30 latex allergy 10.2 RNASE3 IGHE
31 henoch-schoenlein purpura 10.2 RNASE3 CD79A
32 gastritis 10.2
33 echinococcosis 10.2 RNASE3 IGHE CD79A
34 milk allergy 10.2 RNASE3 IGHE CD79A
35 ige responsiveness, atopic 10.2 RNASE3 IGHE
36 exanthem 10.2
37 gastroenteritis 10.2
38 food allergy 10.2
39 otitis media 10.2 RNASE3 IGHE CD79A
40 onchocerciasis 10.1 RNASE3 IGHE
41 paragonimiasis 10.1 TES RNASE3 IGHE
42 gastroesophageal reflux 10.1
43 colorectal cancer 10.1
44 neuronal intranuclear inclusion disease 10.1
45 endometrial cancer 10.1
46 peripheral t-cell lymphoma 10.1
47 arthus reaction 10.1
48 duodenal ulcer 10.1
49 endometrial stromal sarcoma 10.1
50 gastrointestinal system disease 10.1

Graphical network of the top 20 diseases related to Anisakiasis:



Diseases related to Anisakiasis

Symptoms & Phenotypes for Anisakiasis

Symptoms:

12
  • abdominal pain
  • nausea

Drugs & Therapeutics for Anisakiasis

Drugs for Anisakiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Immunologic Factors
2 Antibodies
3 Immunoglobulins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Protists and Nematodes Fish Parasites: From Their Circulation in Ecosystems to Their Impact on Human Health - Prevalence of Fish Allergy in Occupational Settings. Completed NCT02661074
2 Protists and Nematodes Fish Parasites: From Their Circulation in Ecosystems to Their Impact on Human Health - Role of Anisakidae and/or Fish Flesh Antigens in Fish Allergies. Completed NCT02666092

Search NIH Clinical Center for Anisakiasis

Cochrane evidence based reviews: anisakiasis

Genetic Tests for Anisakiasis

Anatomical Context for Anisakiasis

The Foundational Model of Anatomy Ontology organs/tissues related to Anisakiasis:

19
Intestinal Mucosa

MalaCards organs/tissues related to Anisakiasis:

40
Liver, Colon, Lung, Pancreas, Small Intestine, Testes, Lymph Node

Publications for Anisakiasis

Articles related to Anisakiasis:

(show top 50) (show all 614)
# Title Authors PMID Year
1
Novel sequences and epitopes of diagnostic value derived from the Anisakis simplex Ani s 7 major allergen. 54 61
18186812 2008
2
Measurement of serum levels of eosinophil cationic protein in the diagnosis of acute gastrointestinal anisakiasis. 54 61
12848764 2003
3
Specific IgE determination to Ani s 1, a major allergen from Anisakis simplex, is a useful tool for diagnosis. 54 61
12141725 2002
4
Serum CD23 is not altered in gastroallergic anisakiasis, but correlates with the production of specific IgE and the amount of polyclonal stimulation. 54 61
11576082 2001
5
Immunoblot analysis of serum IgG, IgA and IgE responses against larval excretory-secretory antigens of Anisakis simplex in patients with gastric anisakiasis. 54 61
2283472 1990
6
Anisakis Sensitization in the Croatian fish processing workers: Behavioral instead of occupational risk factors? 61
31986138 2020
7
Validation of a Commercial Loop-Mediated Isothermal Amplification (LAMP) Assay for the Rapid Detection of Anisakis spp. DNA in Processed Fish Products. 61
31963107 2020
8
Anisakid Larvae from Anchovies in the South Coast of Korea. 61
31914524 2019
9
Occurrence of Anisakis and Hysterothylacium Nematodes in Atlantic Chub Mackerels from Libyan Coasts. 61
31708677 2019
10
A Case Report of Adhesional Small Bowel Obstruction Caused by Extraintestinal Anisakiasis. 61
31685366 2019
11
Comparison of risk factors between human intestinal and gastric Anisakiasis. 61
31730806 2019
12
Differential Cleaving of Specific Substrates for Cathepsin-Like Activity Shows Cysteine and Serine Protease Activities and a Differential Profile Between Anisakis simplex s.s. and Anisakis pegreffii, Sibling Species Major Etiologic Agents of Anisakiasis. 61
31215796 2019
13
Genome-wide analysis of Anisakis simplex sensu lato: the role of carbohydrate metabolism genes in the parasite's development. 61
31560928 2019
14
Functional Ultrastructure of the Excretory Gland Cell in Zoonotic Anisakids (Anisakidae, Nematoda). 61
31744245 2019
15
Occurrence of Anisakis pegreffii (Nematoda: Anisakidae) Larvae in Imported John Dory (Zeus faber) from Senegalese Coast Sold in Turkish Supermarkets. 61
31172352 2019
16
Adult intussusception caused by colonic anisakis: A case report. 61
31559289 2019
17
Asymptomatic Gastric and Colonic Anisakiasis Detected Simultaneously. 61
30996191 2019
18
Anisakis Nematodes in Fish and Shellfish- from infection to allergies. 61
31338296 2019
19
Clinical and Endoscopic Features of Colonic Anisakiasis in Korea. 61
31533408 2019
20
Differential proteolytic activity in Anisakis simplex s.s. and Anisakis pegreffii, two sibling species from the complex Anisakis simplex s.l., major etiological agents of anisakiasis. 61
30995435 2019
21
Gastric anisakiasis presenting as a vanishing tumor. 61
31312584 2019
22
Gastro-allergic anisakiasis: The first case reported in Colombia and a literature review 61
31529811 2019
23
Easy Detection and Fast Removal of Gastric Anisakis during Narrow-Band Imaging Endoscopy with L-Menthol Administration. 61
31427913 2019
24
Interplay between proinflammatory cytokines, miRNA, and tissue lesions in Anisakis-infected Sprague-Dawley rats. 61
31091271 2019
25
Multidisciplinary approach in study of the zoonotic Anisakis larval infection in the blue mackerel (Scomber australasicus) and the largehead hairtail (Trichiurus lepturus) in Northern Taiwan. 61
31182381 2019
26
Genes expression and in silico studies of functions of trehalases, a highly dispersed Anisakis simplex s. l. specific gene family. 61
30779983 2019
27
'Tingling throat syndrome' as asymptomatic anisakiasis following conveyor belt sushi consumption in Tokyo. 61
30904673 2019
28
Occurrence of larval ascaridoid nematodes in the Argentinean short-finned squid Illex argentinus from the Southwest Atlantic Ocean (off Falkland Islands). 61
30870722 2019
29
Molecular Identification of Anisakis Larvae Extracted by Gastrointestinal Endoscopy from Health Check-up Patients in Korea. 61
31104416 2019
30
[Anisakiasis as differential diagnosis of acute abdominal pain at the emergencydepartment]. 61
31333235 2019
31
Gastric anisakiasis after eating raw salmon. 61
30482477 2019
32
Prevalence of anisakid parasites in fish collected from Apulia region (Italy) and quantification of nematode larvae in flesh. 61
30599456 2019
33
Anisakiasis in the Small Intestine with Excessive Bleeding That Was Difficult to Diagnose Endoscopically. 61
30146603 2019
34
Gastric anisakiasis: a rare cause of abdominal pain. 61
30680902 2019
35
Hepatic anisakiasis mimicking metastatic liver tumour. 61
31238201 2019
36
Parasitic infections and medical expenses according to Health Insurance Review Assessment claims data in South Korea, 2011-2018. 61
31770393 2019
37
Gene expression profiles of antigenic proteins of third stage larvae of the zoonotic nematode Anisakis pegreffii in response to temperature conditions. 61
31441776 2019
38
A case of hepatic anisakiasis caused by Pseudoterranova decipiens mimicking metastatic liver cancer. 61
30514220 2018
39
Anisakiasis: The risks of seafood consumption. 61
30417849 2018
40
Gastric anisakiasis. 61
29908176 2018
41
Woe sushi: gastric anisakiasis. 61
30322583 2018
42
Exploring tumourigenic potential of the parasite Anisakis: a pilot study. 61
30006808 2018
43
Efficiency of Target Larvicides Is Conditioned by ABC-Mediated Transport in the Zoonotic Nematode Anisakis pegreffii. 61
29987147 2018
44
Parasite allergens. 61
29588070 2018
45
Functional insights into the infective larval stage of Anisakis simplex s.s., Anisakis pegreffii and their hybrids based on gene expression patterns. 61
30086708 2018
46
Imaging in gastric anisakiasis. 61
29738996 2018
47
[Anisakiasis Induced Segmental Jejunum Obstruction]. 61
30049176 2018
48
An Overview of Fish-borne Nematodiases among Returned Travelers for Recent 25 Years- Unexpected Diseases Sometimes Far Away from the Origin. 61
29996625 2018
49
Mimicking Small Intestinal Anisakiasis. 61
28823859 2018
50
Colonic Anisakiasis. 61
29229469 2018

Variations for Anisakiasis

Expression for Anisakiasis

Search GEO for disease gene expression data for Anisakiasis.

Pathways for Anisakiasis

Pathways related to Anisakiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.73 TPM4 TPM2 MT-CO2
2 10.51 TPM4 TPM2

GO Terms for Anisakiasis

Cellular components related to Anisakiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Flemming body GO:0090543 8.96 RALA AGAP2
2 muscle thin filament tropomyosin GO:0005862 8.62 TPM4 TPM2

Biological processes related to Anisakiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 8.62 TPM4 TPM2

Molecular functions related to Anisakiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of muscle GO:0008307 8.62 TPM4 TPM2

Sources for Anisakiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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