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MCID: ANS004
MIFTS: 33

Anisometropia

Categories: Eye diseases
Genes Tissues Related diseases Publications Symptoms & Phenotypes Drugs
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Aliases & Classifications for Anisometropia

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MalaCards integrated aliases for Anisometropia:

Name: Anisometropia 12 43 15 71

Classifications:

MalaCards categories:
Anatomical: Eye diseases
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Disease Ontology 12 DOID:12273
ICD9CM 34 367.31
MeSH 43 D015858
SNOMED-CT 67 3289004
ICD10 32 H52.31
UMLS 71 C0003081
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Summaries for Anisometropia

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MalaCards based summary : Anisometropia is related to suppression amblyopia and aniseikonia, and has symptoms including aniseikonia An important gene associated with Anisometropia is DSE (Dermatan Sulfate Epimerase). The drugs Tropicamide and Atropine have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and cortex.

Wikipedia : 74 Anisometropia is the condition in which the two eyes have unequal refractive power. Each eye can be... more...

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Related Diseases for Anisometropia

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Diseases related to Anisometropia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 75)
# Related Disease Score Top Affiliating Genes
1 suppression amblyopia 31.4 TNFRSF10C PLAAT3 DSE DPT
2 aniseikonia 31.3 PLAAT3 DSE DPT
3 accommodative esotropia 30.8 TRARG1 PLAAT3
4 exotropia 30.7 PLAAT3 DPT CYLC1
5 ametropic amblyopia 30.5 DSE DPT CYLC1
6 astigmatism 30.4 TRARG1 IFITM2 DSE DPT CYLC1 CER1
7 presbyopia 30.2 TRARG1 IFITM2 CTSC
8 monofixation syndrome 30.2 TNFRSF10C PLAAT3
9 strabismus 30.1 TNFRSF10C SFTA3 PLAAT3 DSE DPT CYLC1
10 irregular astigmatism 30.1 TRARG1 IFITM2 CYLC1
11 esotropia 30.0 SFTA3 PLAAT3 DSE DPT CYLC1
12 regular astigmatism 29.7 TRARG1 DPT CYLC1 CER1
13 amblyopia 29.4 TNFRSF10C SFTA3 PLAAT3 IFITM2 GCNT2 DSE
14 cycloplegia 29.1 SFTA3 IFITM2 DSE DPT CYLC1 CTSC
15 refractive error 10.9
16 myopia 10.9
17 mechanical strabismus 10.8
18 farsightedness 10.5
19 ocular dominance 10.4
20 monocular esotropia 10.4
21 cataract 10.4
22 alternating exotropia 10.3
23 lacrimal duct defect 10.3
24 retinal detachment 10.3
25 accommodative spasm 10.3 IFITM2 CYLC1
26 choroid cancer 10.2 IFITM2 CYLC1
27 hypertropia 10.2 PLAAT3 DPT
28 exudative vitreoretinopathy 1 10.2
29 neurofibromatosis, type iv, of riccardi 10.2
30 intraocular pressure quantitative trait locus 10.2
31 microvascular complications of diabetes 5 10.2
32 ptosis 10.2
33 corneal ectasia 10.1 TRARG1 IFITM2 CYLC1
34 migraine with or without aura 1 10.1
35 polykaryocytosis inducer 10.1
36 eye disease 10.1
37 glioma 10.1
38 glial tumor 10.1
39 secondary corneal edema 10.0 SFTA3 CYLC1
40 abducens nerve disease 10.0 SFTA3 CYLC1
41 anisocoria 9.9
42 optic nerve hypoplasia, bilateral 9.9
43 myasthenia gravis 9.9
44 ocular motor apraxia 9.9
45 macular degeneration, age-related, 1 9.9
46 microvascular complications of diabetes 1 9.9
47 epilepsy, partial, with pericentral spikes 9.9
48 cataract 23, multiple types 9.9
49 microvascular complications of diabetes 2 9.9
50 exudative vitreoretinopathy 9.9

Graphical network of the top 20 diseases related to Anisometropia:



Diseases related to Anisometropia
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Symptoms & Phenotypes for Anisometropia

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UMLS symptoms related to Anisometropia:


aniseikonia
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Drugs & Therapeutics for Anisometropia

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Drugs for Anisometropia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 34)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tropicamide Approved, Investigational Phase 4 1508-75-4 5593
2
Atropine Approved, Vet_approved Phase 3 51-55-8, 5908-99-6 174174
3
Guaifenesin Approved, Investigational, Vet_approved Phase 3 93-14-1 3516
4
Acetaminophen Approved Phase 3 103-90-2 1983
5
Codeine Approved, Illicit Phase 3 76-57-3 5284371
6 Anti-Arrhythmia Agents Phase 3
7 Respiratory System Agents Phase 3
8 Adjuvants, Anesthesia Phase 3
9 Anesthetics Phase 3
10 Neurotransmitter Agents Phase 3
11 Anti-Asthmatic Agents Phase 3
12 Cholinergic Agents Phase 3
13 Bronchodilator Agents Phase 3
14 Autonomic Agents Phase 3
15 Muscarinic Antagonists Phase 3
16 Mydriatics Phase 3
17 Cholinergic Antagonists Phase 3
18 Parasympatholytics Phase 3
19 Analgesics, Non-Narcotic Phase 3
20 Antipyretics Phase 3
21 Narcotics Phase 3
22 Analgesics Phase 3
23 Analgesics, Opioid Phase 3
24 Chlorpheniramine, phenylpropanolamine drug combination Phase 3
25 Central Nervous System Depressants Phase 3
26 Antitussive Agents Phase 3
27
Timolol Approved Phase 1 26839-75-8 33624 5478
28
Maleic acid Experimental, Investigational Phase 1 110-17-8, 110-16-7 444972
29 Antihypertensive Agents Phase 1
30 Adrenergic Antagonists Phase 1
31 Adrenergic beta-Antagonists Phase 1
32 Pharmaceutical Solutions Phase 1
33 Adrenergic Agents Phase 1
34
Calcium carbonate Approved, Investigational 471-34-1

Interventional clinical trials:

(show all 27)
# Name Status NCT ID Phase Drugs
1 Pilot Study of Prevention Myopia in Children With Low Concentration of Atropine Unknown status NCT00541177 Phase 4 atropine;tropicamide
2 Ten-year Follow-up of Laser in Situ Keratomileusis in Patients 8 to 15 Years Old Completed NCT00800774 Phase 4
3 Anisometropia Amblyopia Improved by Perceptual Learning and Patching Completed NCT00498641 Phase 3
4 Amblyopia Treatment Study Completed NCT00001864 Phase 3 Atropine
5 A Randomized Study of Codeine Plus Paracetamol Versus Placebo for PRK Post-operative Pain Completed NCT02625753 Phase 3 Codeine;paracetamol;placebo
6 Amblyopia Treatment Study: Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia Completed NCT00000170 Phase 3 Atropine
7 Is Non-cycloplegic Photorefraction Applicable for Screening Refractive Risk Factors of Amblyopia? Completed NCT01308307 Phase 2
8 Investigation of Visual Plasticity by a Direct Current Stimulation of Occipital Cortex in Adult Amblyopia Completed NCT00097162 Phase 1
9 Dichoptic Virtual Reality Therapy for Amblyopia in Adults Terminated NCT02246556 Phase 1
10 Phase 1 Study of Topical Beta Blocker to Prevent the Proliferative Stage of Infantile Hemangioma Terminated NCT01434849 Phase 1 topical 0.5% Timolol maleate;Control (placebo) group
11 Ocular Response Analyzer Assessment of Intraocular Pressure and Corneal Biomechanical Properties in Myopic and Anisometropic Patients Under Atropine Treatment Unknown status NCT00658502
12 Prospective Evaluation of a Smartphone Application, GoCheckKidsâ„¢ as a Photo Screening Tool in a Pediatric Population Completed NCT03119675
13 Visual Performance of New Apodized Diffractive Multifocal IOL With Addition of Plus Three Completed NCT01027533
14 Vision Screening of the Four Year Old Children for the Detection of Amblyopia in The Town of Zagreb Completed NCT01430247
15 Performance of Two Photoscreeners With Enhanced Housing Completed NCT04068129
16 Wavefront Analysis and Contrast Sensitivity After Cataract Surgery With Akreos AO Intraocular Lens Implantation: Clinical Comparative Study Completed NCT00863759
17 Standard Amblyopia Therapy in Adult Amblyopes Completed NCT03341780
18 Photorefractive Keratectomy for Anisometropic and Isoametropic Amblyopia in Children Refractory to Conventional Treatment Recruiting NCT03610997
19 Evaluating the Ocular Function of Adults With Autism Spectrum Disorder: Interrelationship Between Blinking Reflex and Cornea Innervation. Recruiting NCT04010422
20 Neurovascular Coupling in Subjects With Amblyopia Recruiting NCT01746693
21 A Randomised Clinical Trial Objectively Comparing the Effect of Patching Therapy With Video Gaming for Amblyopia Recruiting NCT03767985
22 Can we Measure Aniseikonia Tolerance in a Normal Population Recruiting NCT03832335
23 Optimized Visual Recovery in Adult Human Amblyopia Through Binocular Deprivation Active, not recruiting NCT02685423
24 The Effect of Light Deprivation on Visual Functions in Adult Amblyopes Not yet recruiting NCT02799836
25 Macular and Retinal Changes in Unilateral Amblyopia Using Optical Coherence Tomography Not yet recruiting NCT04092361
26 Amblyopia and Neurovascular Coupling in the Retina of Humans Withdrawn NCT00312390
27 Myopia Progression in Children Wearing Near Center and Distance Center Multifocals - a Randomized Controlled Clinical Trial Withdrawn NCT03519490

Search NIH Clinical Center for Anisometropia

Cochrane evidence based reviews: anisometropia

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Genetic Tests for Anisometropia

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Anatomical Context for Anisometropia

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MalaCards organs/tissues related to Anisometropia:

40
Eye, Testes, Cortex, Retina, Brain, Kidney, Endothelial
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Publications for Anisometropia

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Articles related to Anisometropia:

(show top 50) (show all 1543)
# Title Authors PMID Year
1
The influence of orthokeratology compression factor on ocular higher-order aberrations. 61
31264269 2020
2
Correction of presbyopia: old problems with old (and new) solutions. 61
31734940 2020
3
Refractive outcome of intravitreal bevacizumab injection in comparison to spontaneous regression of retinopathy of prematurity (ROP). 61
31790628 2019
4
The impact of vision screening in preschool children on visual function in the Swedish adult population. 61
31127702 2019
5
Pattern of Axial Length Growth in Children Myopic Anisometropes with Orthokeratology Treatment. 61
31821058 2019
6
Can the Red Reflex Test Detect Unequal Refractive Error? 61
31378518 2019
7
Secondary 12-Month Ocular Outcomes of a Phase 1 Dosing Study of Bevacizumab for Retinopathy of Prematurity. 61
31697304 2019
8
Aniseikonia and anisometropia: implications for suppression and amblyopia. 61
30791133 2019
9
Changes in aniseikonia of an axial anisometrope at various stages of orthokeratology lens wear. 61
31732264 2019
10
The tolerance of anisometropia. 61
31773911 2019
11
Dome-shaped macula: a potential protective factor for visual acuity after cataract surgery in patients with high myopia. 61
30602448 2019
12
Distribution of Refractive Errors among Healthy Infants and Young Children between the Age of 6 to 36 Months in Kuala Lumpur, Malaysia-A Pilot Study. 61
31783494 2019
13
Determinants of subjective patient-reported quality of vision after small-incision lenticule extraction. 61
31585852 2019
14
Refractive Errors and Amblyopia Among Children Screened by the UCLA Preschool Vision Program in Los Angeles County. 61
31647932 2019
15
The Role of Binocularity in Anisometropic Amblyopia. 61
31486743 2019
16
Differential Experience-Dependent Plasticity of Form and Motion Mechanisms in Anisometropic Amblyopia. 61
31574139 2019
17
[Evaluation of Ophthalmic Follow-up Care of Former Pre-term and Full-term Infants Aged from 4 to 10 Years in Germany - Results of the Wiesbaden Prematurity Study (WPS)]. 61
29117610 2019
18
Intraocular Lens Implantation during Early Childhood: A Report by the American Academy of Ophthalmology. 61
31230794 2019
19
Smartphone photography for screening amblyogenic conditions in children. 61
31546480 2019
20
Anisometropia and isoametropia associated with microstrabismus: effectiveness of late anti-amblyopia treatment. 61
31612190 2019
21
Eye Conditions in Infants and Children: Vision Screening and Routine Eye Examinations. 61
31454212 2019
22
Two-Year Outcomes of Infants with Stage 2 or Higher Retinopathy of Prematurity: Results from a Large Multicenter Registry. 61
31480086 2019
23
Is the severity of refractive error dependent on the quantity and extent of retinal laser ablation for retinopathy of prematurity? 61
31554947 2019
24
Diagnostic accuracy and agreement between visual acuity charts for detecting significant refractive errors in preschoolers. 61
31566805 2019
25
Meeting the need for corrective spectacles in visually impaired Chinese school children: the potential of ready-made spectacles. 61
30279277 2019
26
Prevalence of anterior polar cataracts in children and risk factors for amblyopia. 61
30390373 2019
27
Morphologic changes in the visual cortex of patients with anisometropic amblyopia: a surface-based morphometry study. 61
31375091 2019
28
The effect of asymmetrical accommodation on anisometropic amblyopia treatment outcomes. 61
31301347 2019
29
A Randomized Noninferiority Trial of Wearing Adjustable Glasses versus Standard and Ready-made Spectacles among Chinese Schoolchildren: Wearability and Evaluation of Adjustable Refraction III. 61
31543351 2019
30
Analysis of the current preschool vision screening in Denmark. 61
30218489 2019
31
Impaired Fellow Eye Motion Perception and Abnormal Binocular Function. 61
31387113 2019
32
Foveal avascular zone and macular vessel density after correction for magnification error in unilateral amblyopia using optical coherence tomography angiography. 61
31382925 2019
33
Comparison of amblyopia in schoolchildren in Ireland and Northern Ireland: a population-based observational cross-sectional analysis of a treatable childhood visual deficit. 61
31401612 2019
34
Factors determining the outcome of paediatric exotropia surgery. 61
31424031 2019
35
Prevalence, Characteristics, and Risk Factors of Moderate or High Hyperopia among Multiethnic Children 6 to 72 Months of Age: A Pooled Analysis of Individual Participant Data. 61
30822446 2019
36
Comparative study of visual dysfunctions in 6-10-year-old very preterm- and full-term-born children. 61
29916121 2019
37
Elucidation of the more myopic eye in anisometropia: the interplay of laterality, ocular dominance, and anisometropic magnitude. 61
31270453 2019
38
Don't Miss This! Red Flags in the Pediatric Eye Examination: Abnormal Red Reflex. 61
31329054 2019
39
Surgical Timing for Congenital Ptosis Should Not Be Determined Solely by the Presence of Anisometropia. 61
30789542 2019
40
Oral fluoxetine in the management of amblyopic patients aged between 10 and 40 years old: a randomized clinical trial. 61
30783259 2019
41
Assessing the change of anisometropia in unilateral myopic children receiving monocular orthokeratology treatment. 61
30782426 2019
42
Prevalence and Associations of Myopic Anisometropia in Chinese Adults. 61
31211720 2019
43
Evaluation of the Spot Vision Screener for children with limited access to ocular health care. 61
31028870 2019
44
Factors influencing stereopsis in patients with both refractive accommodative esotropia and amblyopia. 61
29704131 2019
45
A Randomized Clinical Trial of Immediate versus Delayed Glasses for Moderate Hyperopia in 1- and 2-Year-Olds. 61
30615896 2019
46
Fixation instability during binocular viewing in anisometropic and strabismic children. 61
30006273 2019
47
Self-perception in Children Aged 3 to 7 Years With Amblyopia and Its Association With Deficits in Vision and Fine Motor Skills. 61
30763432 2019
48
Contralateral eye comparison of the long-term visual quality and stability between implantable collamer lens and laser refractive surgery for myopia. 61
30187653 2019
49
Flushing versus not flushing the interface during small-incision lenticule extraction. 61
30846349 2019
50
Binocular Visual Discomfort after First Eye Cataract Surgery: An Inattentive Burning Issue. 61
31086142 2019
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Variations for Anisometropia

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Expression for Anisometropia

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Search GEO for disease gene expression data for Anisometropia.
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Pathways for Anisometropia

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GO Terms for Anisometropia

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Biological processes related to Anisometropia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8.96 PILRB GREM1
2 determination of dorsal identity GO:0048263 8.62 GREM1 CER1

Molecular functions related to Anisometropia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 BMP binding GO:0036122 8.96 GREM1 CER1
2 morphogen activity GO:0016015 8.62 GREM1 CER1
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Sources for Anisometropia

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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