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MCID: ANS004
MIFTS: 33

Anisometropia

Categories: Eye diseases
Genes Tissues Related diseases Publications Symptoms & Phenotypes Drugs
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Aliases & Classifications for Anisometropia

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MalaCards integrated aliases for Anisometropia:

Name: Anisometropia 12 44 15 73

Classifications:

MalaCards categories:
Anatomical: Eye diseases
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External Ids:

Disease Ontology 12 DOID:12273
ICD10 33 H52.31
ICD9CM 35 367.31
MeSH 44 D015858
SNOMED-CT 68 3289004
UMLS 73 C0003081
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Summaries for Anisometropia

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MalaCards based summary : Anisometropia is related to amblyopia and astigmatism, and has symptoms including aniseikonia An important gene associated with Anisometropia is DPT (Dermatopontin). The drugs Triamcinolone and Atropine have been mentioned in the context of this disorder. Affiliated tissues include eye, cortex and testes.

Wikipedia : 76 Anisometropia is the condition in which the two eyes have unequal refractive power. Each eye can be... more...

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Related Diseases for Anisometropia

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Diseases related to Anisometropia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
# Related Disease Score Top Affiliating Genes
1 amblyopia 30.4 CHN1 DPT DSE OPTN
2 astigmatism 30.3 ADAMTSL4 DPT GREM1
3 accommodative esotropia 30.2 CHN1 COG8
4 esotropia 29.9 CHN1 COG8 OPTN
5 strabismus 10.5
6 myopia 10.4
7 aniseikonia 10.4
8 refractive error 10.3
9 lacrimal duct defect 10.2
10 ocular dominance 10.2
11 neurofibromatosis, type i 10.1
12 cataract 10.1
13 microvascular complications of diabetes 5 10.0
14 glioma 10.0
15 ametropic amblyopia 10.0 CHN1 DPT
16 disuse amblyopia 9.9 CHN1 DPT
17 retinal detachment 9.9
18 glaucoma 3, primary congenital, a 9.9
19 myasthenia gravis 9.9
20 glaucoma 3, primary infantile, b 9.9
21 craniosynostosis 9.9
22 hemangioma 9.9
23 exudative vitreoretinopathy 9.9
24 primary congenital glaucoma 9.9
25 ptosis 9.9
26 cycloplegia 9.9
27 suppression amblyopia 9.9
28 open-angle glaucoma 9.9
29 irregular astigmatism 9.9
30 optic nerve glioma 9.9
31 monofixation syndrome 9.9
32 myasthenia gravis congenital 9.9
33 depression 9.9
34 hypotropia 9.8 CHN1 OPTN
35 lens disease 9.6 ADAMTSL4 OPTN

Graphical network of the top 20 diseases related to Anisometropia:



Diseases related to Anisometropia
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Symptoms & Phenotypes for Anisometropia

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UMLS symptoms related to Anisometropia:


aniseikonia
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Drugs & Therapeutics for Anisometropia

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Drugs for Anisometropia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved Phase 3 124-94-7 31307
2
Atropine Approved, Vet_approved Phase 3 51-55-8, 5908-99-6 174174
3 triamcinolone acetonide Phase 3
4 Triamcinolone hexacetonide Phase 3
5 Triamcinolone diacetate Phase 3
6 Anti-Arrhythmia Agents Phase 3
7 Peripheral Nervous System Agents Phase 3
8 Anesthetics Phase 3
9 Cholinergic Antagonists Phase 3
10 Parasympatholytics Phase 3
11 Mydriatics Phase 3,Phase 2
12 Cholinergic Agents Phase 3
13 Muscarinic Antagonists Phase 3
14 Autonomic Agents Phase 3
15 Anti-Asthmatic Agents Phase 3
16 Neurotransmitter Agents Phase 3
17 Respiratory System Agents Phase 3
18 Bronchodilator Agents Phase 3
19 Adjuvants, Anesthesia Phase 3
20
Calcium Carbonate Approved, Investigational 471-34-1
21
Glucosamine Approved, Investigational Not Applicable 3416-24-8 439213
22 Hypolipidemic Agents Not Applicable
23 Glucuronyl glucosamine glycan sulfate Not Applicable
24 Hypoglycemic Agents Not Applicable
25 Antimetabolites Not Applicable
26 Anticoagulants Not Applicable
27 Fibrinolytic Agents Not Applicable
28 Lipid Regulating Agents Not Applicable

Interventional clinical trials:

(show all 24)
# Name Status NCT ID Phase Drugs
1 Ten-year Follow-up of Laser in Situ Keratomileusis in Patients 8 to 15 Years Old Completed NCT00800774 Phase 4
2 Surgical Management of Pseudophakic and Aphakic Retinal Detachment; a Randomized Clinical Trial Unknown status NCT00370279 Phase 3
3 Anisometropia Amblyopia Improved by Perceptual Learning and Patching Completed NCT00498641 Phase 3
4 Amblyopia (Lazy Eye) Treatment Study Completed NCT00001864 Phase 3 Atropine
5 Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia Completed NCT00000170 Phase 3 Atropine
6 Full-time Bangerter Filters Versus Part-time Daily Patching for Moderate Amblyopia in Children Completed NCT00525174 Phase 3
7 Is Non-cycloplegic Photorefraction Applicable for Screening Refractive Risk Factors of Amblyopia? Completed NCT01308307 Phase 2
8 Visual Cortex Stimulation in Patients With Amblyopia Completed NCT00097162 Phase 1
9 Dichoptic Virtual Reality Therapy for Amblyopia in Adults Terminated NCT02246556 Phase 1
10 Ocular Response Analyzer Assessment of Intraocular Pressure and Corneal Biomechanical Properties in Myopic and Anisometropic Patients Under Atropine Treatment Unknown status NCT00658502
11 Vision Screening for the Detection of Amblyopia Unknown status NCT01430247 Not Applicable
12 Standard Amblyopia Therapy in Adult Amblyopes Completed NCT03341780
13 Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner Completed NCT01832883
14 Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner Completed NCT01726842
15 Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner Completed NCT01706991
16 Evaluation of a Smartphone Application, GoCheckKids™ as a Photo Screening Tool in a Pediatric Population Completed NCT03119675 Not Applicable
17 Neurovascular Coupling in Subjects With Amblyopia Recruiting NCT01746693 Not Applicable
18 Photorefractive Keratectomy for Severe Anisometropia and Isoametropia Associated With Amblyopia Recruiting NCT03610997 Not Applicable
19 Patching or Gaming as Amblyopia Treatment? Recruiting NCT03767985 Not Applicable
20 Shanghai High Myopia Study Recruiting NCT03062085
21 Light-deprivation Utilized to Mitigate Amblyopia Active, not recruiting NCT02685423 Not Applicable
22 The Effect of Light Deprivation on Visual Functions in Adult Amblyopes Not yet recruiting NCT02799836 Not Applicable
23 Excimer Laser Surgery for Anisometropic Amblyopia Not yet recruiting NCT03342235 Not Applicable
24 Amblyopia and Neurovascular Coupling in the Retina of Humans Withdrawn NCT00312390 Not Applicable

Search NIH Clinical Center for Anisometropia

Cochrane evidence based reviews: anisometropia

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Genetic Tests for Anisometropia

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Anatomical Context for Anisometropia

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MalaCards organs/tissues related to Anisometropia:

41
Eye, Cortex, Testes, Retina
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Publications for Anisometropia

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Articles related to Anisometropia:

(show top 50) (show all 281)
# Title Authors Year
1
Anisometropia and Refractive Status in Children with Bilateral Congenital Nasolacrimal Duct Obstruction. ( 29544578 )
2018
2
Rapid neuroadaptation to surgically-induced aniseikonia in a 17-year-old patient with high preoperative anisometropia: A case report. ( 29577095 )
2018
3
Anisometropia and refractive status in children with unilateral congenital nasolacrimal duct obstruction. ( 29675347 )
2018
4
ASYMMETRIC DIABETIC RETINOPATHY PROGRESSION IN PATIENTS WITH AXIAL ANISOMETROPIA. ( 29547453 )
2018
5
Missense mutation in SLIT2 associated with congenital myopia, anisometropia, connective tissue abnormalities, and obesity. ( 30111362 )
2018
6
Mirror image hypermetropic anisometropia in a pair of monozygotic twins. ( 30458238 )
2018
7
Progressive anisometropia and orthokeratology: a case report. ( 28393402 )
2018
8
Contrast sensitivity of amblyopic eyes in children with myopic anisometropia. ( 30054940 )
2018
9
Progression of High Anisometropia in Children. ( 28510775 )
2017
10
Measurement of peripapillary retinal nerve fiber layer thickness and macular thickness in anisometropia using spectral domain optical coherence tomography: a prospective study. ( 28260856 )
2017
11
Prevalence and association of refractive anisometropia with near work habits among young schoolchildren: The evidence from a population-based study. ( 28273153 )
2017
12
A Prospective Study of Anterior Segment Ocular Parameters in Anisometropia. ( 28367046 )
2017
13
Observations on the relationship between anisometropia, amblyopia and strabismus. ( 28404522 )
2017
14
Exome sequencing identifies a novel UNC5D mutation in a severe myopic anisometropia family: A case report. ( 28614238 )
2017
15
Anisometropia at Age 5 Years After Unilateral Intraocular Lens Implantation During Infancy in the Infant Aphakia Treatment Study. ( 28526552 )
2017
16
Effect of artificial anisometropia in dominant and nondominant eyes on stereoacuity. ( 28576202 )
2017
17
Retina and Optic Disc Characteristics in Amblyopic and Non-amblyopic Eyes of Patients with Myopic or Hyperopic Anisometropia. ( 28182148 )
2017
18
Stereoacuity after Wavefront-guided Photorefractive Keratectomy in Anisometropia. ( 28791058 )
2017
19
Stereopsis and fusion in anisometropia according to the presence of amblyopia. ( 28889226 )
2017
20
Anisometropia of spherical equivalent and astigmatism among myopes: a 23-year follow-up study of prevalence and changes from childhood to adulthood. ( 28481050 )
2017
21
Comparison of perceptual eye positions among patients with different degrees of anisometropia. ( 28953639 )
2017
22
Longitudinal Development of Refractive Error in Children With Accommodative Esotropia: Onset, Amblyopia, and Anisometropia. ( 27116548 )
2016
23
Comparison of the Wave Amplitude of Visually Evoked Potential in Amblyopic Eyes between Patients with Esotropia and Anisometropia and a Normal Group. ( 26989279 )
2016
24
Ocular Myasthenia Gravis in Monozygotic Twins with Mirror-image Myopic Anisometropia. ( 27729761 )
2016
25
Anisometropia and Ptosis in Patients with Monocular Elevation Deficiency. ( 27806813 )
2016
26
HIGH MYOPIA AND DIABETIC RETINOPATHY: A Contralateral Eye Study in Diabetic Patients With High Myopic Anisometropia. ( 27749693 )
2016
27
Comparison of Anisometropia and Refractive Status in Children With Unilateral and Bilateral Congenital Nasolacrimal Duct Obstruction. ( 27224951 )
2016
28
Prevalence and Associations of Anisometropia in Children. ( 26962694 )
2016
29
Interocular Comparison of Anterior and Posterior Segment Findings and Laterality in Hyperopic Anisometropia. ( 27541970 )
2016
30
Evaluation of the anatomic and refractive differences in hyperopic anisometropia. ( 26887566 )
2016
31
Dominant Eye and Visual Evoked Potential of Patients with Myopic Anisometropia. ( 27340660 )
2016
32
Effect of myopic anisometropia on anterior and posterior ocular segment parameters. ( 27262559 )
2016
33
Anisometropia of ocular refractive and biometric measures among 66- to 79-year-old female twins. ( 27273930 )
2016
34
Effect of Anisometropia on the Predictability and Accuracy of Refractive Surgery. ( 27467042 )
2016
35
Correlation of axial length and corneal curvature with diopter in eyes of adults with anisometropia. ( 26550307 )
2015
36
Refractive Changes in Amblyopic Children with High Anisometropia. ( 26258279 )
2015
37
Myopic anisometropia: ocular characteristics and aetiological considerations. ( 24939167 )
2014
38
Anisometropia in children with neurofibromatosis type 1 and unilateral optic nerve glioma. ( 24924279 )
2014
39
Corneal refractive surgery and phakic intraocular lens for treatment of amblyopia caused by high myopia or anisometropia in children. ( 24890172 )
2014
40
Limited change in anisometropia and aniso-axial length over 13 years in myopic children enrolled in the Correction of Myopia Evaluation Trial. ( 24576881 )
2014
41
Timing of congenital dacryostenosis resolution and the development of anisometropia. ( 24682178 )
2014
42
Anisometropia in children with neurofibromatosis type 1 and unilateral optic glioma. ( 25438951 )
2014
43
Longitudinal increase in anisometropia in older adults. ( 24276578 )
2014
44
Comment on anisometropia magnitude and visual deficits in previously untreated anisometropic amblyopia. ( 25540769 )
2014
45
The amblyopic eye in subjects with anisometropia show increased saccadic latency in the delayed saccade task. ( 25352790 )
2014
46
Simulated hyperopic anisometropia and reading, visual information processing, and reading-related eye movement performance in children. ( 25414177 )
2014
47
Profile of anisometropia and aniso-astigmatism in children: prevalence and association with age, ocular biometric measures, and refractive status. ( 23233258 )
2013
48
Anisometropia magnitude and visual deficits in previously untreated anisometropic amblyopia. ( 24195034 )
2013
49
Calibration and validation of nine objective vision screeners with contact lens-induced anisometropia. ( 23565714 )
2013
50
The relationship between anisometropia and amblyopia. ( 23773832 )
2013
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Variations for Anisometropia

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Expression for Anisometropia

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Search GEO for disease gene expression data for Anisometropia.
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Pathways for Anisometropia

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GO Terms for Anisometropia

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Cellular components related to Anisometropia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Golgi membrane GO:0000139 8.8 COG8 DSE OPTN

Biological processes related to Anisometropia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 apoptotic process GO:0006915 9.13 ADAMTSL4 GREM1 UNC5D
2 collagen fibril organization GO:0030199 8.62 DPT GREM1
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Sources for Anisometropia

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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