Aliases & Classifications for Anisometropia

MalaCards integrated aliases for Anisometropia:

Name: Anisometropia 12 44 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:12273
ICD9CM 34 367.31
MeSH 44 D015858
SNOMED-CT 67 3289004
ICD10 32 H52.31
UMLS 70 C0003081

Summaries for Anisometropia

MalaCards based summary : Anisometropia is related to suppression amblyopia and amblyopia, and has symptoms including aniseikonia An important gene associated with Anisometropia is CRYAA (Crystallin Alpha A). The drugs Atropine and Anti-Arrhythmia Agents have been mentioned in the context of this disorder. Affiliated tissues include eye, cortex and retina.

Wikipedia : 73 Anisometropia is when two eyes have unequal refractive power. Generally a difference in power of two... more...

Related Diseases for Anisometropia

Diseases related to Anisometropia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 99)
# Related Disease Score Top Affiliating Genes
1 suppression amblyopia 31.2 PHOX2A HNMT CHN1
2 amblyopia 31.1 PAX6 HNMT CRYAA CHN1
3 refractive error 30.9 ZNF644 SLC39A5 SCO2 CRYAA
4 cycloplegia 30.7 SFTA3 SCO2
5 strabismus 30.5 TSPAN10 SFTA3 PHOX2A PAX6 CRYAA CHN1
6 exotropia 30.2 PHOX2A PAX6 CRYAA CHN1
7 ametropic amblyopia 30.2 PHOX2A CHN1
8 esotropia 30.1 SFTA3 PHOX2A PAX6 CRYAA CHN1
9 myopia 30.0 ZNF644 SLC39A5 SCO2 PAX6 NDUFAF7 LUM
10 accommodative esotropia 29.8 TSPAN10 PHOX2A PDE6G CHN1
11 congenital ptosis 29.6 PHOX2A PAX6 CRYAA CHN1
12 degenerative myopia 29.4 ZNF644 SCO2 NDUFAF7 LUM
13 mechanical strabismus 10.7
14 astigmatism 10.7
15 aniseikonia 10.5
16 ocular dominance 10.3
17 monocular esotropia 10.3
18 cataract 10.3
19 farsightedness 10.3
20 congenital aphakia 10.3 PAX6 CRYAA
21 axenfeld-rieger syndrome, type 1 10.3 PAX6 CRYAA
22 sclerocornea 10.3 PAX6 CRYAA
23 orbital disease 10.2 PHOX2A CRYAA
24 ectropion 10.2 PAX6 CRYAA
25 vitreous disease 10.2 PAX6 CRYAA
26 alternating exotropia 10.2
27 abducens nerve disease 10.2 SFTA3 CHN1
28 papillorenal syndrome 10.2 PAX6 CRYAA
29 hypotropia 10.2 PHOX2A CHN1
30 paralytic squint 10.2 PHOX2A CHN1
31 hypertropia 10.2 PHOX2A CHN1
32 lens subluxation 10.2 PAX6 CRYAA
33 enophthalmos 10.2 PHOX2A CRYAA
34 partial third-nerve palsy 10.1 PHOX2A CHN1
35 eye degenerative disease 10.1 SFTA3 PAX6 CRYAA
36 achromatopsia 10.1 SFTA3 PAX6 CRYAA
37 lacrimal duct defect 10.1
38 retinal detachment 10.1
39 eyelid disease 10.1 PAX6 CRYAA
40 juvenile glaucoma 10.1 SCO2 PAX6 CRYAA
41 keratitis, hereditary 10.1 PHOX2A PAX6 CRYAA
42 exudative vitreoretinopathy 5 10.1 TSPAN10 PDE6G
43 iris disease 10.1 PAX6 CRYAA
44 duane-radial ray syndrome 10.1 PHOX2A CHN1
45 cornea plana 10.1 LUM CRYAA
46 congenital nystagmus 10.0 PAX6 CRYAA
47 exudative vitreoretinopathy 1 10.0
48 intraocular pressure quantitative trait locus 10.0
49 microvascular complications of diabetes 5 10.0
50 ptosis 10.0

Graphical network of the top 20 diseases related to Anisometropia:



Diseases related to Anisometropia

Symptoms & Phenotypes for Anisometropia

UMLS symptoms related to Anisometropia:


aniseikonia

Drugs & Therapeutics for Anisometropia

Drugs for Anisometropia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Atropine Approved, Vet_approved Phase 3 5908-99-6, 51-55-8 174174
2 Anti-Arrhythmia Agents Phase 3
3 Neurotransmitter Agents Phase 3
4 Respiratory System Agents Phase 3
5 Anesthetics Phase 3
6 Parasympatholytics Phase 3
7 Mydriatics Phase 3
8 Cholinergic Agents Phase 3
9 Muscarinic Antagonists Phase 3
10 Anti-Asthmatic Agents Phase 3
11 Bronchodilator Agents Phase 3
12 Cholinergic Antagonists Phase 3

Interventional clinical trials:

(show all 12)
# Name Status NCT ID Phase Drugs
1 Ten-year Follow-up of Laser in Situ Keratomileusis in Patients 8 to 15 Years Old Completed NCT00800774 Phase 4
2 Anisometropia Amblyopia Improved by Perceptual Learning and Patching Completed NCT00498641 Phase 3
3 Amblyopia Treatment Study Completed NCT00001864 Phase 3 Atropine
4 Dichoptic Virtual Reality Therapy for Amblyopia in Adults Terminated NCT02246556 Phase 1
5 Can we Measure Aniseikonia Tolerance in a Normal Population Unknown status NCT03832335
6 Ocular Response Analyzer Assessment of Intraocular Pressure and Corneal Biomechanical Properties in Myopic and Anisometropic Patients Under Atropine Treatment Unknown status NCT00658502
7 Vision Screening of the Four Year Old Children for the Detection of Amblyopia in The Town of Zagreb Completed NCT01430247
8 Performance of Two Photoscreeners With Enhanced Housing Completed NCT04068129
9 Neurovascular Coupling in Subjects With Amblyopia Recruiting NCT01746693
10 Photorefractive Keratectomy for Anisometropic and Isoametropic Amblyopia in Children Refractory to Conventional Treatment Active, not recruiting NCT03610997
11 Patching Versus Dichoptic Stimulation Using Virtual Reality in Anisometropic Amblyopia Not yet recruiting NCT04302701
12 The Effect of Light Deprivation on Visual Functions in Adult Amblyopes Withdrawn NCT02799836

Search NIH Clinical Center for Anisometropia

Cochrane evidence based reviews: anisometropia

Genetic Tests for Anisometropia

Anatomical Context for Anisometropia

MalaCards organs/tissues related to Anisometropia:

40
Eye, Cortex, Retina, Endothelial, Kidney

Publications for Anisometropia

Articles related to Anisometropia:

(show top 50) (show all 1629)
# Title Authors PMID Year
1
Increased Incidence of Ophthalmologic Findings in Children With Concurrent Isolated Nonsyndromic Metopic Suture Abnormalities and Deformational Cranial Vault Asymmetry. 61
32929979 2021
2
Associations between visual function and magnitude of refractive error for emmetropic to moderately hyperopic 4- and 5-year-old children in the Vision in Preschoolers - Hyperopia in Preschoolers Study. 61
33772848 2021
3
The development of and recovery from form-deprivation myopia in infant rhesus monkeys reared under reduced ambient lighting. 61
33799131 2021
4
Effect of induced anisometropia on stereopsis and surgical tasks in a simulated environment. 61
33595474 2021
5
Implementing ICHOM standard set for cataract surgery at IPO-Porto (Portugal): clinical outcomes, quality of life and costs. 61
33673817 2021
6
Referral outcomes from a vision screening program for school-aged children. 61
32771327 2021
7
Successes and shortfalls of community Plusoptix photoscreening: results from the iSee study in Southwestern Ontario. 61
32891567 2021
8
Refraction and its development in young adults born prematurely and screened for retinopathy of prematurity. 61
33528099 2021
9
Incidence of Clinically Significant Aniseikonia Following Encircling Scleral Buckle Surgery: An Evaluation of Refractive and Axial Length Changes Requiring Intervention. 61
33546116 2021
10
[Vision screening for children: Recommended practices from AFSOP]. 61
33388188 2021
11
Measuring aniseikonia tolerance range for stereoacuity - a tool for the refractive surgeon. 61
32558241 2021
12
Long-term follow-up of an amblyopia treatment study: change in visual acuity 15 years after occlusion therapy. 61
32657530 2021
13
Clarifying the effect of refractive errors and stereopsis on traumatic dental injuries in childhood. 61
32937007 2021
14
Topically instilled caffeine selectively alters emmetropizing responses in infant rhesus monkeys. 61
33428866 2021
15
Efficacy of part-time occlusion in amblyopia in Indian children. 61
33323591 2021
16
Co-existence of myopia and amblyopia in a guinea pig model with monocular form deprivation. 61
33569412 2021
17
The Effects of 0.01% Atropine on Adult Myopes' Contrast Sensitivity. 61
33679306 2021
18
Gender and age distribution of refractive errors in an optometric clinical population. 61
33487574 2021
19
Prevalence of Amblyopia and Associated Risk Factors in Tibetan Grade One Children. 61
33279900 2021
20
Prevalence and risk factor for refractive error in rural Chinese adults in Kailu, Inner Mongolia. 61
33104269 2021
21
A novel approach for scleral fixation using Carlevale lens. 61
33517768 2021
22
Technical Report: A New Device Attached to a Smartphone for Objective Vision Screening. 61
33394927 2021
23
Morning Glory Disc Anomaly with Contractile Peripapillary Staphyloma in an 18-Month-Old Girl. 61
33762786 2021
24
Impaired visual acuity caused by uncorrected refractive errors and amblyopia in a German paediatric cohort. 61
33104264 2021
25
Fixational eye movements abnormalities and rate of visual acuity and stereoacuity improvement with part time patching. 61
33441575 2021
26
The Success of Unilateral Surgery for Constant and Intermittent Exotropia and Factors Affecting It in a Large Scandinavian Case Series. 61
33495796 2021
27
Correction of pseudophakic presbyopia using Lasik with aspheric ablation profiles and a micro-monovision protocol. 61
32902784 2021
28
Visian Implantable Collamer Lens Behavior in Descemet Membrane Endothelial Keratoplasty Surgery. 61
32618853 2021
29
Choroidal vessel density in unilateral hyperopic amblyopia using en-face optical coherence tomography. 61
33267849 2020
30
Evaluation of Bruch's membrane opening-minimum rim width and retinal nerve fiber layer thickness in adults with anisometropic amblyopia. 61
32979546 2020
31
Does anisometropia affect the ciliary muscle thickness? An ultrasound biomicroscopy study. 61
33083933 2020
32
Using OCT Fixation Shift to Assess Eccentric Fixation in Children With Residual Amblyopia. 61
33262904 2020
33
Binocularity outcomes following treatment for retinopathy of prematurity. 61
33160917 2020
34
Comparison between distance and near visual acuity in amblyopes. 61
33181679 2020
35
Intraconal Orbital Hidrocystoma in an Infant. 61
33235165 2020
36
The return of phacoemulsification after emergency status related to COVID-19: the experience of a tertiary referral center. 61
33229967 2020
37
Strabismus prevalence and associated factors among pediatric patients in southern Ethiopia: a cross-sectional study. 61
33076734 2020
38
Characterization of Unique Lens Morphology in a Cohort of Children with Familial Exudative Vitreoretinopathy. 61
32141791 2020
39
Novel Cross-Linked Ocular Bandage Gel Improves Reepithelialization After Photorefractive Keratectomy: A Randomized, Masked Prospective Study. 61
32701012 2020
40
Short Term Presence of Subretinal Fluid in Central Serous Chorioretinopathy Affects Retinal Thickness and Function. 61
33114519 2020
41
Subjective Happiness and Satisfaction in Postoperative Anisometropic Patients after Refractive Surgery for Myopia. 61
33126654 2020
42
One-year results of 0.01% atropine with orthokeratology (AOK) study: a randomised clinical trial. 61
32776533 2020
43
Associations of Eye-Related Quality of Life With Vision, Visuomotor Function, and Self-Perception in Children With Strabismus and Anisometropia. 61
32926105 2020
44
Ophthalmologic outcome of premature infants with or without retinopathy of prematurity at 5-6 years of age. 61
33209767 2020
45
Binocular discrepancy in lateral rectus muscle attachment in intermittent exotropia with eye dominance. 61
32314031 2020
46
Prevalence of Strabismus and Its Impact on Vision-Related Quality of Life: Results from the German Population-Based Gutenberg Health Study. 61
32312635 2020
47
Ophthalmological outcomes of unilateral coronal synostosis in young children. 61
32753041 2020
48
Factors Associated with Impaired Motor Skills in Strabismic and Anisometropic Children. 61
32845292 2020
49
A comparative study of orthokeratology and low-dose atropine for the treatment of anisomyopia in children. 61
32843658 2020
50
What can anisometropia tell us about eye growth? 61
32855163 2020

Variations for Anisometropia

Expression for Anisometropia

Search GEO for disease gene expression data for Anisometropia.

Pathways for Anisometropia

GO Terms for Anisometropia

Biological processes related to Anisometropia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 visual perception GO:0007601 9.26 PDE6G PAX6 LUM CRYAA
2 eye development GO:0001654 8.8 SLC39A5 SCO2 PAX6

Sources for Anisometropia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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