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MCID: ANS004
MIFTS: 32

Anisometropia

Categories: Eye diseases
Genes Tissues Related diseases Publications Symptoms & Phenotypes Drugs
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Aliases & Classifications for Anisometropia

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MalaCards integrated aliases for Anisometropia:

Name: Anisometropia 12 45 15 74

Classifications:

MalaCards categories:
Anatomical: Eye diseases
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External Ids:

Disease Ontology 12 DOID:12273
ICD9CM 36 367.31
MeSH 45 D015858
SNOMED-CT 69 3289004
ICD10 34 H52.31
UMLS 74 C0003081
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Summaries for Anisometropia

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MalaCards based summary : Anisometropia is related to amblyopia and suppression amblyopia, and has symptoms including aniseikonia An important gene associated with Anisometropia is DPT (Dermatopontin). The drugs Triamcinolone and Atropine have been mentioned in the context of this disorder. Affiliated tissues include eye, cortex and retina, and related phenotype is Increased G1 length, increased G2 length.

Wikipedia : 77 Anisometropia is the condition in which the two eyes have unequal refractive power. Each eye can be... more...

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Related Diseases for Anisometropia

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Diseases related to Anisometropia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
# Related Disease Score Top Affiliating Genes
1 amblyopia 30.9 DPT DSE
2 suppression amblyopia 10.7
3 strabismus 10.5
4 mechanical strabismus 10.5
5 myopia 10.4
6 aniseikonia 10.4
7 astigmatism 10.4
8 monocular esotropia 10.3
9 refractive error 10.3
10 esotropia 10.3
11 lacrimal duct defect 10.2
12 ocular dominance 10.2
13 accommodative esotropia 10.2
14 neurofibromatosis, type i 10.1
15 neurofibromatosis, type iv, of riccardi 10.1
16 cataract 10.1
17 ptosis 10.1
18 retinal detachment 10.0
19 microvascular complications of diabetes 5 10.0
20 glioma 10.0
21 glaucoma 3, primary congenital, a 9.9
22 myasthenia gravis 9.9
23 glaucoma 3, primary infantile, b 9.9
24 craniosynostosis 9.9
25 hemangioma 9.9
26 exudative vitreoretinopathy 9.9
27 primary congenital glaucoma 9.9
28 congenital ptosis 9.9
29 cycloplegia 9.9
30 open-angle glaucoma 9.9
31 irregular astigmatism 9.9
32 optic nerve glioma 9.9
33 monofixation syndrome 9.9
34 myasthenia gravis congenital 9.9
35 depression 9.9

Graphical network of the top 20 diseases related to Anisometropia:



Diseases related to Anisometropia
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Symptoms & Phenotypes for Anisometropia

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UMLS symptoms related to Anisometropia:


aniseikonia

GenomeRNAi Phenotypes related to Anisometropia according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased G1 length, increased G2 length GR00237-A 8.62 EED LRPPRC
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Drugs & Therapeutics for Anisometropia

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Drugs for Anisometropia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved Phase 3 124-94-7 31307
2
Atropine Approved, Vet_approved Phase 3 5908-99-6, 51-55-8 174174
3 Triamcinolone hexacetonide Phase 3
4 triamcinolone acetonide Phase 3
5 Triamcinolone diacetate Phase 3
6 Autonomic Agents Phase 3,Not Applicable
7 Parasympatholytics Phase 3
8 Anesthetics Phase 3
9 Cholinergic Antagonists Phase 3
10 Respiratory System Agents Phase 3
11 Anti-Arrhythmia Agents Phase 3
12 Adjuvants, Anesthesia Phase 3
13 Muscarinic Antagonists Phase 3
14 Peripheral Nervous System Agents Phase 3,Not Applicable
15 Bronchodilator Agents Phase 3
16 Mydriatics Phase 3,Phase 2
17 Neurotransmitter Agents Phase 3,Not Applicable
18 Anti-Asthmatic Agents Phase 3
19 Cholinergic Agents Phase 3
20
Calcium Carbonate Approved, Investigational 471-34-1
21
Methamphetamine Approved, Illicit Not Applicable 537-46-2 10836
22
Dopamine Approved Not Applicable 62-31-7, 51-61-6 681
23 Dopamine Uptake Inhibitors Not Applicable
24 Adrenergic Agents Not Applicable
25 Central Nervous System Stimulants Not Applicable
26 Neurotransmitter Uptake Inhibitors Not Applicable
27 Sympathomimetics Not Applicable
28 Dopamine Agents Not Applicable

Interventional clinical trials:

(show all 26)
# Name Status NCT ID Phase Drugs
1 Ten-year Follow-up of Laser in Situ Keratomileusis in Patients 8 to 15 Years Old Completed NCT00800774 Phase 4
2 Surgical Management of Pseudophakic and Aphakic Retinal Detachment; a Randomized Clinical Trial Unknown status NCT00370279 Phase 3
3 Anisometropia Amblyopia Improved by Perceptual Learning and Patching Completed NCT00498641 Phase 3
4 Amblyopia (Lazy Eye) Treatment Study Completed NCT00001864 Phase 3 Atropine
5 Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia Completed NCT00000170 Phase 3 Atropine
6 Full-time Bangerter Filters Versus Part-time Daily Patching for Moderate Amblyopia in Children Completed NCT00525174 Phase 3
7 Is Non-cycloplegic Photorefraction Applicable for Screening Refractive Risk Factors of Amblyopia? Completed NCT01308307 Phase 2
8 Visual Cortex Stimulation in Patients With Amblyopia Completed NCT00097162 Phase 1
9 Dichoptic Virtual Reality Therapy for Amblyopia in Adults Terminated NCT02246556 Phase 1
10 Ocular Response Analyzer Assessment of Intraocular Pressure and Corneal Biomechanical Properties in Myopic and Anisometropic Patients Under Atropine Treatment Unknown status NCT00658502
11 Vision Screening for the Detection of Amblyopia Unknown status NCT01430247 Not Applicable
12 Light-deprivation Utilized to Mitigate Amblyopia Unknown status NCT02685423 Not Applicable
13 Standard Amblyopia Therapy in Adult Amblyopes Completed NCT03341780
14 Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner Completed NCT01832883
15 Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner Completed NCT01726842
16 Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner Completed NCT01706991
17 Evaluation of a Smartphone Application, GoCheckKids™ as a Photo Screening Tool in a Pediatric Population Completed NCT03119675 Not Applicable
18 Hyperopia Treatment Study 1 (HTS1) - Glasses vs Observation Completed NCT01515475 Not Applicable
19 Neurovascular Coupling in Subjects With Amblyopia Recruiting NCT01746693 Not Applicable
20 Photorefractive Keratectomy for Severe Anisometropia and Isoametropia Associated With Amblyopia Recruiting NCT03610997 Not Applicable
21 A New Measurement of Anseikonia Tolerance Recruiting NCT03832335
22 Patching or Gaming as Amblyopia Treatment? Recruiting NCT03767985 Not Applicable
23 Shanghai High Myopia Study Recruiting NCT03062085
24 The Effect of Light Deprivation on Visual Functions in Adult Amblyopes Not yet recruiting NCT02799836 Not Applicable
25 Excimer Laser Surgery for Anisometropic Amblyopia Not yet recruiting NCT03342235 Not Applicable
26 Amblyopia and Neurovascular Coupling in the Retina of Humans Withdrawn NCT00312390 Not Applicable

Search NIH Clinical Center for Anisometropia

Cochrane evidence based reviews: anisometropia

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Genetic Tests for Anisometropia

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Anatomical Context for Anisometropia

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MalaCards organs/tissues related to Anisometropia:

42
Eye, Cortex, Retina, Testes
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Publications for Anisometropia

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Articles related to Anisometropia:

(show top 50) (show all 286)
# Title Authors Year
1
Aniseikonia and anisometropia: implications for suppression and amblyopia. ( 30791133 )
2019
2
Contrast sensitivity of amblyopic eyes in children with myopic anisometropia. ( 30054940 )
2019
3
Assessing the change of anisometropia in unilateral myopic children receiving monocular orthokeratology treatment. ( 30782426 )
2019
4
Surgical Timing for Congenital Ptosis Should Not Be Determined Solely by the Presence of Anisometropia. ( 30789542 )
2019
5
Comparison of the Effect of Different Types of Experimental Anisometropia on Stereopsis Measured with Titmus, Randot and TNO Stereotests. ( 30820287 )
2019
6
Interocular Comparison of Anterior and Posterior Segment Findings and Laterality in Hyperopic Anisometropia. ( 27541970 )
2018
7
Progressive anisometropia and orthokeratology: a case report. ( 28393402 )
2018
8
Anisometropia and Refractive Status in Children with Bilateral Congenital Nasolacrimal Duct Obstruction. ( 29544578 )
2018
9
ASYMMETRIC DIABETIC RETINOPATHY PROGRESSION IN PATIENTS WITH AXIAL ANISOMETROPIA. ( 29547453 )
2018
10
Anisometropia and refractive status in children with unilateral congenital nasolacrimal duct obstruction. ( 29675347 )
2018
11
Rapid neuroadaptation to surgically-induced aniseikonia in a 17-year-old patient with high preoperative anisometropia: A case report. ( 29577095 )
2018
12
Missense mutation in SLIT2 associated with congenital myopia, anisometropia, connective tissue abnormalities, and obesity. ( 30111362 )
2018
13
Mirror image hypermetropic anisometropia in a pair of monozygotic twins. ( 30458238 )
2018
14
Observations on the relationship between anisometropia, amblyopia and strabismus. ( 28404522 )
2017
15
Stereopsis and fusion in anisometropia according to the presence of amblyopia. ( 28889226 )
2017
16
Effect of myopic anisometropia on anterior and posterior ocular segment parameters. ( 27262559 )
2017
17
HIGH MYOPIA AND DIABETIC RETINOPATHY: A Contralateral Eye Study in Diabetic Patients With High Myopic Anisometropia. ( 27749693 )
2017
18
Retina and Optic Disc Characteristics in Amblyopic and Non-amblyopic Eyes of Patients with Myopic or Hyperopic Anisometropia. ( 28182148 )
2017
19
Measurement of peripapillary retinal nerve fiber layer thickness and macular thickness in anisometropia using spectral domain optical coherence tomography: a prospective study. ( 28260856 )
2017
20
Prevalence and association of refractive anisometropia with near work habits among young schoolchildren: The evidence from a population-based study. ( 28273153 )
2017
21
A Prospective Study of Anterior Segment Ocular Parameters in Anisometropia. ( 28367046 )
2017
22
Anisometropia of spherical equivalent and astigmatism among myopes: a 23-year follow-up study of prevalence and changes from childhood to adulthood. ( 28481050 )
2017
23
Progression of High Anisometropia in Children. ( 28510775 )
2017
24
Anisometropia at Age 5 Years After Unilateral Intraocular Lens Implantation During Infancy in the Infant Aphakia Treatment Study. ( 28526552 )
2017
25
Effect of artificial anisometropia in dominant and nondominant eyes on stereoacuity. ( 28576202 )
2017
26
Exome sequencing identifies a novel UNC5D mutation in a severe myopic anisometropia family: A case report. ( 28614238 )
2017
27
Stereoacuity after Wavefront-guided Photorefractive Keratectomy in Anisometropia. ( 28791058 )
2017
28
Comparison of perceptual eye positions among patients with different degrees of anisometropia. ( 28953639 )
2017
29
Longitudinal Development of Refractive Error in Children With Accommodative Esotropia: Onset, Amblyopia, and Anisometropia. ( 27116548 )
2016
30
Evaluation of the anatomic and refractive differences in hyperopic anisometropia. ( 26887566 )
2016
31
Prevalence and Associations of Anisometropia in Children. ( 26962694 )
2016
32
Comparison of the Wave Amplitude of Visually Evoked Potential in Amblyopic Eyes between Patients with Esotropia and Anisometropia and a Normal Group. ( 26989279 )
2016
33
Comparison of Anisometropia and Refractive Status in Children With Unilateral and Bilateral Congenital Nasolacrimal Duct Obstruction. ( 27224951 )
2016
34
Anisometropia of ocular refractive and biometric measures among 66- to 79-year-old female twins. ( 27273930 )
2016
35
Dominant Eye and Visual Evoked Potential of Patients with Myopic Anisometropia. ( 27340660 )
2016
36
Effect of Anisometropia on the Predictability and Accuracy of Refractive Surgery. ( 27467042 )
2016
37
Ocular Myasthenia Gravis in Monozygotic Twins with Mirror-image Myopic Anisometropia. ( 27729761 )
2016
38
Anisometropia and Ptosis in Patients with Monocular Elevation Deficiency. ( 27806813 )
2016
39
Refractive Changes in Amblyopic Children with High Anisometropia. ( 26258279 )
2015
40
Correlation of axial length and corneal curvature with diopter in eyes of adults with anisometropia. ( 26550307 )
2015
41
Comment on anisometropia magnitude and visual deficits in previously untreated anisometropic amblyopia. ( 25540769 )
2014
42
Corneal refractive surgery and phakic intraocular lens for treatment of amblyopia caused by high myopia or anisometropia in children. ( 24890172 )
2014
43
Simulated hyperopic anisometropia and reading, visual information processing, and reading-related eye movement performance in children. ( 25414177 )
2014
44
Anisometropia in children with neurofibromatosis type 1 and unilateral optic glioma. ( 25438951 )
2014
45
Longitudinal increase in anisometropia in older adults. ( 24276578 )
2014
46
Limited change in anisometropia and aniso-axial length over 13 years in myopic children enrolled in the Correction of Myopia Evaluation Trial. ( 24576881 )
2014
47
Timing of congenital dacryostenosis resolution and the development of anisometropia. ( 24682178 )
2014
48
Anisometropia in children with neurofibromatosis type 1 and unilateral optic nerve glioma. ( 24924279 )
2014
49
Myopic anisometropia: ocular characteristics and aetiological considerations. ( 24939167 )
2014
50
The amblyopic eye in subjects with anisometropia show increased saccadic latency in the delayed saccade task. ( 25352790 )
2014
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Variations for Anisometropia

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Expression for Anisometropia

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Search GEO for disease gene expression data for Anisometropia.
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Pathways for Anisometropia

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GO Terms for Anisometropia

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Cellular components related to Anisometropia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Golgi membrane GO:0000139 8.8 COG8 DSE GCNT2
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Sources for Anisometropia

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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