THC2
MCID: ANK019
MIFTS: 18

Ankrd26-Related Thrombocytopenia (THC2)

Categories: Blood diseases, Bone diseases, Genetic diseases, Immune diseases, Rare diseases

Aliases & Classifications for Ankrd26-Related Thrombocytopenia

MalaCards integrated aliases for Ankrd26-Related Thrombocytopenia:

Name: Ankrd26-Related Thrombocytopenia 24
Thrombocytopenia 2 24
Thc2 24

Characteristics:

GeneReviews:

24
Penetrance Penetrance for thrombocytopenia is complete in individuals with an ankrd26 pathogenic variant. the risk of transformation to a myeloid malignancy is variable [noris et al 2013]...

Classifications:



Summaries for Ankrd26-Related Thrombocytopenia

MalaCards based summary : Ankrd26-Related Thrombocytopenia, also known as thrombocytopenia 2, is related to thrombocytopenia 2 and radioulnar synostosis with amegakaryocytic thrombocytopenia 2. An important gene associated with Ankrd26-Related Thrombocytopenia is ANKRD26 (Ankyrin Repeat Domain 26). Affiliated tissues include myeloid, bone and testes.

GeneReviews: NBK507664

Related Diseases for Ankrd26-Related Thrombocytopenia

Diseases in the Thrombocytopenia family:

Thrombocytopenia 2 Thrombocytopenia 3
Thrombocytopenia 1 Thrombocytopenia 4
Thrombocytopenia 5 Thrombocytopenia 6
Acquired Thrombocytopenia Thrombocytopenia Due to Platelet Alloimmunization
Primary Thrombocytopenia Ankrd26-Related Thrombocytopenia
Myh9 Related Thrombocytopenia

Diseases related to Ankrd26-Related Thrombocytopenia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 thrombocytopenia 2 12.4
2 radioulnar synostosis with amegakaryocytic thrombocytopenia 2 12.4
3 thrombocytopenia 10.4
4 gray platelet syndrome 10.1

Symptoms & Phenotypes for Ankrd26-Related Thrombocytopenia

Drugs & Therapeutics for Ankrd26-Related Thrombocytopenia

Search Clinical Trials , NIH Clinical Center for Ankrd26-Related Thrombocytopenia

Genetic Tests for Ankrd26-Related Thrombocytopenia

Anatomical Context for Ankrd26-Related Thrombocytopenia

MalaCards organs/tissues related to Ankrd26-Related Thrombocytopenia:

41
Myeloid, Bone, Testes

Publications for Ankrd26-Related Thrombocytopenia

Articles related to Ankrd26-Related Thrombocytopenia:

# Title Authors Year
1
Clinic, pathogenic mechanisms and drug testing of two inherited thrombocytopenias, ANKRD26-related Thrombocytopenia and MYH9-related diseases. ( 29545013 )
2018
2
Successful use of eltrombopag for surgical preparation in a patient with ANKRD26-related thrombocytopenia. ( 27276516 )
2016
3
ANKRD26-related thrombocytopenia and myeloid malignancies. ( 24030261 )
2013

Variations for Ankrd26-Related Thrombocytopenia

Expression for Ankrd26-Related Thrombocytopenia

Search GEO for disease gene expression data for Ankrd26-Related Thrombocytopenia.

Pathways for Ankrd26-Related Thrombocytopenia

GO Terms for Ankrd26-Related Thrombocytopenia

Sources for Ankrd26-Related Thrombocytopenia

3 CDC
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9 Cosmic
10 dbSNP
11 DGIdb
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28 GO
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34 ICD10 via Orphanet
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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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